ライフサイエンスコーパス: first-order rate constant

1 yl carbonates 9 and 10, respectively, with a first-order rate constant (2-Bu(4)N: k = 18.5 +/- 0.1 x

2 e aquated (G/H(2)O) intermediate (4) (pseudo-first-order rate constant = (3.62 +/- 0.04) x 10(-5) s(-

3 howed a linear dependence between the pseudo-first-order rate constant and the pKa of the leaving gro

4 We measured pseudo-first-order rate constants and uptake coefficients based

5 nd Finfinity are the amplitude, the apparent first-order rate constant, and the fluorescence end poin

6 overall ChOOH and PLOOH to LDL with apparent first-order rate constants approximately 60 and approxim

7 The limiting first order rate constants are 160 and 4 s(-1).

8 The pseudo-first-order rate constants are not linearly related to t

9 The first-order rate constants are obtained from the literat

10 First-order rate constants at 293 K for exchange of the

11 es (I(2), RP(o)) are single-exponential with first order rate constant beta(CR).

12 The rate of appearance (with a pseudo-first-order rate constant ca. 10(-6) s-1) of tandem doub

13 f the beta-cyclodextrin concentration with a first-order rate constant, common to both RNA and DNA, o

14 The pseudo-first-order rate constant describing fluorescence decay

15 First-order rate constants describing distribution and e

16 could be resolved and occurred with a pseudo-first-order rate constant determined at 4 microM [125I]T

17 Second, the first order rate constant for ATP hydrolysis remains rel

18 The first order rate constant for ATPase activity exhibits a

19 The first order rate constant for conversion of the initial

20 The increase in the observed pseudo-first order rate constant for formation of the trimer, k

21 The estimated pseudo-first order rate constant for macroscopic blockade was 4

22 The first order rate constant for phosphorylation increases

23 The first order rate constant for splicing of this intein, w

24 Doxorubicin leakage can be described by first order rate constant for transport across the lipid

25 The first order rate constant for unwinding was reduced only

26 Subunit exchange experiments yield first order rate constants for dimer dissociation that r

27 First order rate constants for formation of MzII(a) and

28 The first order rate constants for inactivation (k2) of the

29 ents was evaluated by determining the pseudo first order rate constants for inhibition of CTP functio

30 The first order rate constants for mitochondrial depolarizat

31 The first order rate constants for the dissociation, k(off),

32 equilibrium dissociation constants (KD) and first- order rate constants for the mutant proteins.

33 p is the neutrophil concentration, g is the first-order rate constant for bacterial growth, and t is

34 The value of the first-order rate constant for conversion of the enzyme-s

35 In model studies it is shown that the first-order rate constant for decarboxylation can indeed

36 The pH dependence of the first-order rate constant for decay of the alpha-aminoac

37 tuent results in a 3400-fold increase in the first-order rate constant for deuterium exchange.

38 lf-reaction, the pH dependence of the pseudo-first-order rate constant for disappearance of the alpha

39 e for greater than 33 days, the value of the first-order rate constant for dissociation of E.[(3)H]GW

40 An inverse dependence of the first-order rate constant for effusion out of the protei

41 The pseudo-first-order rate constant for factor Xa inhibition by an

42 Mutation of Arg98 to lysine decreases the first-order rate constant for flavin reduction by 180-fo

43 ine as the amine substrate, the value of the first-order rate constant for flavin reduction decreases

44 The apparent first-order rate constant for free sulfhydryl loss (0.08

45 +/- 0.005 min-1) is similar to the apparent first-order rate constant for inactivation (0.067 +/- 0.

46 and 12.9 +/- 3.8 mM were determined for the first-order rate constant for inactivation and the disso

47 The pseudo-first-order rate constant for inactivation varied with p

48 P by Sp-NONOate, or Ki, was 0.47 mM, and the first-order rate constant for irreversible inhibition of

49 nstant for its reaction with N(3)(-) and the first-order rate constant for its reaction with the aque

50 tant of 1.1 x 10(4) M-1.s-1, compared to the first-order rate constant for LiPII reduction by VA.

51 ics, and that the dependence of the observed first-order rate constant for persulfide cleavage by DTT

52 account discrimination in binding and in the first-order rate constant for phosphodiester bond scissi

53 studies showed that T201A T4moH had a faster first-order rate constant for product formation than T20

54 ne results in a decrease in the value of the first-order rate constant for reduction of 35-fold and a

55 were used, k(exch) was equal to k(-)(2), the first-order rate constant for reversal of the acyl-enzym

56 (3) The first-order rate constant for the approach to steady-sta

57 nstant and a value of 221+/-36 s(-1) for the first-order rate constant for the associated conformatio

58 The first-order rate constant for the ATPgammaS-mediated iso

59 carboxylation kinetics, and the activity and first-order rate constant for the CA hydration reaction

60 The first-order rate constant for the change from K+ to Na+

61 The logarithm of the first-order rate constant for the change from Na+ to K+

62 The observed first-order rate constant for the change in energy trans

63 %, CK enzyme activity by 34%, and the pseudo first-order rate constant for the CK reaction by 50%.

64 show as much as an 18-fold variation in the first-order rate constant for the conformational change,

65 The first-order rate constant for the conversion of the init

66 The first-order rate constant for the conversion of the init

67 The first-order rate constant for the folding of the alpha s

68 Kinetic analyses show that the apparent first-order rate constant for the inactivation of CVB3 b

69 The first-order rate constant for the inactivation of the ty

70 The first-order rate constant for the reaction of 1 and 2 in

71 The D242S and D242E mutations reduced the first-order rate constant for the reaction of MnP compou

72 The F190V mutation increased the first-order rate constant for the reduction of compound

73 (PCP), we found it was clear that the pseudo-first-order rate constant for the reduction of resazurin

74 0) concentration of 300 microM, the apparent first-order rate constant for this process is approximat

75 a function of GdnHCl concentration yields a first-order rate constant for unfolding of (9.0 +/- 7.5)

76 At 4 degreesC, the first-order rate constant for uridylylation by UDP-gluco

77 ime (tau(i)), where tau(i)(-1) is the pseudo-first-order rate constant for water efflux.

78 based on goodness-of-fit criteria, included first-order rate constants for all disposition processes

79 concentrations and transfer processes using first-order rate constants for all processes known to be

80 Pseudo-first-order rate constants for amidine nitrosation in aq

81 the MuA-DNA complexes are preassembled, the first-order rate constants for both DNA cleavage and DNA

82 275 degrees C in the gas phase have provided first-order rate constants for cis,trans interconversion

83 s diastereomer in one DNA strand affects the first-order rate constants for cleavage in the unmodifie

84 The pseudo-first-order rate constants for cleavage of the thio anal

85 compound I reduction (k2app), and decreased first-order rate constants for compound II reduction (k3

86 First-order rate constants for deprotonation of the alph

87 Here, we have measured first-order rate constants for each key step in the reac

88 ndividual subunits were combined into single first-order rate constants for each subunit which were c

89 of 1,600 M(-)(1) x cm(-)(1)), with apparent first-order rate constants for formation and decay of ap

90 tibiotics were identified in terms of pseudo-first-order rate constants for formation of reactive spe

91 Apparent first-order rate constants for GSH/PHGPX-induced peroxid

92 The first-order rate constants for intramolecular associatio

93 (+)( )()from theoretical computations of the first-order rate constants for intramolecular electron t

94 In contrast, the first-order rate constants for MnPII reduction by Mn(II)

95 The apparent first-order rate constants for NADP(+) release and NADPH

96 in situ infrared spectroscopy provide pseudo-first-order rate constants for reactions with a variety

97 The pseudo-first-order rate constants for rebinding to the alpha an

98 The pseudo first-order rate constants for the aquation of 1 to 2 in

99 Pseudo-first-order rate constants for the demetalation (kobs) a

100 First-order rate constants for the enantiomerization of

101 We measured pseudo-first-order rate constants for the first nucleotide addi

102 The pseudo-first-order rate constants for the H5-catalyzed AT inhib

103 Pseudo-first-order rate constants for the insertion into 1-DMSO

104 The observed first-order rate constants for the monoexponential (k(ob

105 rate in the Compound I species (K(bind)) and first-order rate constants for the oxidation reactions (

106 f high salt concentration (1 M NaCl), pseudo-first-order rate constants for the reaction of moenomyci

107 First-order rate constants for the reactions of ions wer

108 yst for the oxidation of NaBr with H(2)O(2), first-order rate constants for the selenoxide eliminatio

109 The first-order rate constants for the single and double mut

110 The first-order rate constants for the thermally induced tra

111 The pseudo-first-order rate constants for these systems were determ

112 molar absorptivity and fluence-based pseudo-first-order rate constants for transformation of the six

113 Moreover, although the apparent first-order rate constants for transmembrane ion flux in

114 The surface area-normalized pseudo-first-order rate constant, for example, associated with

115 The first-order rate constant increases with increasing [ATP

116 The pH-rate profile for the observed first-order rate constant is bell-shaped with two ioniza

117 y chromatography column by 10% if the pseudo-first-order rate constant is larger than 0.1 s(-1).

118 ht complex in the absence of MgATP (apparent first-order rate constant k = 0.007 s-1) and that MgATP

119 H/D KIE on the first-order rate constant k(cat) ((D)k = 3.72) has been

120 h ferrozine concentrations, and an effective first-order rate constant k(Fz) for the disappearance of

121 nd (3) a larger 320 000-fold decrease in the first-order rate constant k(s) for hydrolysis of this co

122 The observed first-order rate constants k(1)(25 degrees C) were found

123 , yield activation barriers DeltaG(ET)() and first-order rate constants k(ET) for electron-transfer b

124 A comparison of the first-order rate constants k(HO)[HO(-)] = 4.5 x 10(-11)

125 erature in high yield, and the corresponding first-order rate constants k(OH), k(Cl), and k(Br) are o

126 The first-order rate constant (k(2)) for formation of the ac

127 ng a normal 3',5'-linkage was cleaved with a first-order rate constant (k(2)) of 0.91 min(-)(1).

128 f selection show a >400-fold increase in the first-order rate constant (k(cat)) on a DNA substrate, r

129 (based on [(14)C]Ch transfer) increasing the first-order rate constant (k) approximately 7-fold.

130 First-order rate constants (k = 1.91-14.2 x 10(-5) s(-1)

131 Observed pseudo-first-order rate constants (k(obs)) of the hydride-trans

132 The first-order rate constant, k(1)((ISP-f)), predicted from

133 The pseudo-first-order rate constants, k(obsd), are pH independent

134 eaction with a substrate in solution (pseudo-first-order rate constant, k1(f)), accounts for the impo

135 d intermediates autodecomposed slowly with a first order rate constant k2 = 0.003 min(-1); when a red

136 dissociation constant Kd of 13.3 mM and the first-order rate constant k2 of 0.22 s-1.

137 The apparent first-order rate constants (ka) of PBP2a acylation by be

138 diffusion constant corresponds to an average first-order rate constant kHOP of 2(+/-1) x 10(6) s(-1)

139 Observed pseudo-first-order rate constants (kobs) ranged from 3.8 x 10(-

140 resented in terms of the net observed pseudo-first-order rate constant, kobs, rather than in terms of

141 First-order rate constants kOP were 1,600 +/- 300 min-1

142 ific light attenuation is corrected for, the first-order rate constants kpdPAR, kpdUVA, and kpdUVB wi

143 Using PhoB in excess of P-VanS, a pseudo-first-order rate constant (kxfer) of 0.2 min-1 for phosp

144 n flux, with over 10-fold differences in the first-order rate constant manifested in molecular specie

145 ce of the substituent, as pointed out by the first-order rate constants measured at 25 degrees C.

146 Extrapolation of first-order rate constants measured at elevated temperat

147 Pseudo-first-order rate constant measurements were made for con

148 was informed by the development of a pseudo first-order rate constant model, and tested in a paper-b

149 360 nm decays in a biphasic manner with two first-order rate constants, neither of which are affecte

150 Pseudo-first-order rate constants obtained at -50 degrees C wit

151 the enzyme-TIMP-1 complex dissociates with a first order rate constant of 0.00026 s-1.

152 requiring MgATP hydrolysis, with an apparent first order rate constant of 0.02 s-1 compared with 140

153 oxorubicin dissolution can be described by a first order rate constant of 1.0x10(-9)cms(-1) at 37 deg

154 kyrin in resealed cells with a half-time and first order rate constant of 12 +/- 3.6 min and 0.060 +/

155 reduced by substrate and exhibits a limiting first order rate constant of 230 s(-1) at pH 7.5 and 30

156 19 decomposed back to the ferric form with a first order rate constant of 29.4 +/- 3.4 s(-1), which i

157 enous ankyrin from IOVs with a half-time and first order rate constant of 42 +/- 14 min and 0.017 +/-

158 The first order rate constant of C-terminal cleavage is 1.2

159 The pseudo first order rate constant of dithiothreitol-dependent N-

160 quation of 1 to yield 2 occurs with a pseudo-first-order rate constant of (4.15 +/- 0.04) x 10(-5) s(

161 8 nM and reacts to the tight complex with a first-order rate constant of 0.003 s-1.

162 the 5'-deazaFAD reductase autoxidizes with a first-order rate constant of 0.007 s(-)(1).

163 followed single exponential kinetics, with a first-order rate constant of 0.2-0.5 s-1 at 24 degrees C

164 severs phalloidin-stabilized F-actin with a first-order rate constant of 0.25 s-1.

165 xhibited saturation behavior with a limiting first-order rate constant of 0.8 s(-1) and a K(d) of < o

166 and free Mn protoporphyrin IX occurs with a first-order rate constant of 1.2 x 10(-2) s(-1) at 20 de

167 urs 3 orders of magnitude more slowly with a first-order rate constant of 1.67 x 10(-5) s(-1).

168 the absence of NADPH-P450 reductase, with a first-order rate constant of 14 min(-1) at 25 degrees C.

169 h model phosphatidylcholine vesicles, with a first-order rate constant of 5.3 s-1 (t(1)/(2) = 130 ms)

170 enzyme-TPPS] complex of 1.3 10(4)mol/L and a first-order rate constant of 6.6 10(-1)s(-1) for dissoci

171 tterns for the pH dependence of k(bkdn), the first-order rate constant of breakdown, were found.

172 Tumor perfusion, as measured by the first-order rate constant of gadolinium plasma to tissue

173 nificantly increased values for the apparent first-order rate constant of inactivation.

174 which reacts with acetonitrile with a pseudo-first-order rate constant of k = 1 x 10(6) s(-1) and is

175 (4-) decayed to ground state products with a first-order rate constant of k = 2 x 10(3) s(-1).

176 s that lead to product as well as the pseudo-first-order rate constant of the reaction.

177 The first-order rate constant of the redox reaction between

178 presence and absence of heparin, the pseudo-first-order rate constant of thrombin inhibition (kobs)

179 1.2 +/- 0.4 and 8.2 +/- 0.05 and displaying first-order rate constants of <0.7 x 10(-6) s(-1) at pH

180 s of approximately 0.86 and 8.0 +/- 0.1 with first-order rate constants of <7 x 10(-6) s(-1) at pH va

181 Pseudo-first-order rate constants of 2-MeImpG and ImpG hydrolys

182 Q168R with UDP-glucose proceed with maximum first-order rate constants of 2.2 x 10(-)4 s-1 and 4.2 x

183 nzyme undergoes deuridylylation with maximum first-order rate constants of 4.8 x 10(-)4 s-1 and 1.68

184 parable, both being associated with apparent first-order rate constants of approximately 1 x 10(-)(4)

185 We report experimentally determined first-order rate constants of MeHg photolysis in three w

186 k(1) and k(-4) are the first-order rate constants of the transition induced by

187 of the hyperbolic dependence of the observed first-order rate constant on alpha,beta-methyleneadenosi

188 The saturable dependence of the observed first-order rate constants on the concentrations of AT i

189 An adjustable kinetic model that reduces the first-order rate constants proportional to neighboring g

190 B. thetaiotaomicron had larger first order rate constants than all other organisms unde

191 n initial lag phase and gave apparent pseudo-first order rate constants that increased with protein c

192 narrow range of values was observed for the first-order rate constant that describes lactate efflux,

193 of the core polymerase resulted in a set of first-order rate constants that varied in a hyperbolic m

194 biaryl compounds in quantitative yields with first-order rate constants that were independent of the

195 The pseudo first-order rate constant to regenerate the di-cobalt be

196 uilibration is known to be modulated by four first-order rate constants: two (T1a(-1) and T1b(-1)) fo

197 nce of distinguishable events and the pseudo-first-order rate constants under "standard" conditions (

198 rst-order kinetic model, resulting in pseudo-first-order rate constant values of 0.10, 0.12, 0.20, an

199 adenovirus receptor showed that the observed first-order rate constant varies with receptor concentra

200 Plots of the log of the observed first-order rate constant versus denaturant concentratio

201 Examination of the first-order rate constant versus enzyme concentration su

202 ned as the slopes of the plots of the pseudo-first-order rate constants versus the concentrations of

203 tive intermediates in CsX because the pseudo-first-order rate constant was nearly same for the two ma

204 , n = 10); however, the myocardial CK pseudo first-order rate constant was normal in LVH (0.36 +/- 0.

205 aturation behaviour when the observed pseudo first-order rate constants were plotted against NO2(-) c

206 re fitted to a first-order equation, and the first-order rate constants were plotted against the dNTP

207 le second-order mechanism and initial pseudo first-order rate constants which differ significantly fr