1 the NMR crystallography approach, rendering
firstly (
1)H assignment straightforward, and being secon
2 Firstly,
10 patients and 12 healthy control subjects wer
3 Firstly,
62 isolates from 29 timepoints from three in vi
4 e origin of HAAs in milk and dairy products,
firstly a chromatographic method was developed for their
5 Therefore, this study proposes
firstly a new fitting approach describing oxygen consumi
6 We compare two distinct geometries:
firstly,
a bilayer structure comprised of arrays of meta
7 Firstly,
a collection of 'morphs' of solved structures r
8 Firstly,
a common OTA extraction solvent and a labeling
9 Firstly,
a comparative study of diabetic patients with d
10 Firstly,
a comparative study was made of eight methods f
11 Firstly,
a Focus Group study was performed to identify s
12 Firstly,
a hierarchical set of filtering calculations ha
13 Firstly,
a multilevel structural equation modelling appr
14 Firstly,
a pooled RNAi screen identified TRIM14 to effec
15 We focused on two hypotheses:
firstly,
a previous deterministic model has suggested th
16 Firstly,
a set of reference transcripts was defined that
17 Firstly,
a simple approach based on fluorescence has bee
18 Firstly,
a single inductive coil is placed on the top of
19 We
firstly adjust to 1 the initial robustness of a network.
20 nation differed from those reported earlier:
firstly,
aerially borne conidia were harvested, and then
21 Validation studies, carried out
firstly against Uniprot entries with expert binding-site
22 consequences: an increased tendency towards,
firstly,
aggregation in vivo, and, secondly, aberrant in
23 Here we modify this scheme by
firstly allowing for a richer structure and secondly by
24 Porcine DNA was
firstly amplified using loop-mediated isothermal amplifi
25 Firstly,
an effective acetylcholinesterase immobilized e
26 Firstly,
an efficient bioadsorbent, i.e, microwave-activ
27 nity based biosensors, are described herein;
firstly,
an immunosensor based on SPR transduction was r
28 Firstly,
analysis of the transheterozygote gnom(B4049/em
29 e area and depth of the core region increase
firstly,
and then stay stable over the laser fluence of
30 equencing of the bacterial 16S rRNA gene was
firstly applied to investigate the rhizospheric bacteria
31 the present work, MCR-ALS and U-PCA/RBL were
firstly applied to remove the contribution of unexpected
32 from the I-band in three different contexts;
firstly as isolated domains with the boundaries defined
33 ual role in type III endonuclease reactions:
Firstly,
as an allosteric activator, promoting DNA assoc
34 We
firstly assess Deltaleaf variation at the leaf and stand
35 ay be first guided by ED and then the flavor
firstly associated with ED, whereas the partial caloric
36 e to expand antiretroviral therapy coverage,
firstly at CD4 cell count lower than 350 cells per muL,
37 ylose contained in the continuous matrix was
firstly attacked by calcium ions at low lime levels (<0.
38 Firstly,
axenic amastigotes showed higher infectivity an
39 differ from conventional B cells (B-2 cells)
firstly because they are thought to require contact with
40 d in which the pairs of unlabeled DNA probes
firstly bind to HPV16 E6 and E7 RNAs to form the DNA-RNA
41 Firstly,
both MT-II and iodo-MT-II were effective at sup
42 Firstly,
Br-cGMP induced a concentration-dependent incre
43 This was shown
firstly by anti-CTLA-4 reversal of the anti-CD3 stop-sig
44 ed and carbonyl-phenol adducts were produced
firstly by epoxide-ring opening initiated by the attack
45 l-to-cell spread mechanisms are exemplified:
firstly by human retroviruses, which rely upon transient
46 uctive approaches to mimic the human enzyme:
firstly by mutating RadA to increase sequence identity w
47 Firstly by the introduction of an accurate method of ass
48 data were analyzed in two independent ways:
firstly,
by rigid-body modeling of the scattering data u
49 We conclude that,
firstly,
calcium dynamics can be accurately modeled usin
50 ture and partial density of states have been
firstly calculated to study the luminescent and heteroep
51 Firstly,
can markers of the microbial community be ident
52 in, the strain induced by silicon nitride is
firstly characterized through the changes in photolumine
53 Firstly,
co-expression network analysis is applied to ex
54 Firstly,
co-staining for K8 and K14 demonstrates that so
55 temperature (HPHT) data with high precision
firstly complement and close the gap between the resisti
56 Firstly,
computer simulations confirmed that the method
57 This confirmed two long-held hypotheses,
firstly concerning the interactive role of population de
58 genes involved in stomach carcinogenesis, we
firstly constructed a carcinogen-induced mouse gastric t
59 The DNA-array is
firstly converted into antibody-array using antibody-DNA
60 explained by dual actions of nimodipine in,
firstly,
decreasing the form of tolerance to ethanol tha
61 Firstly,
delta(18)O fruit water and corresponding source
62 Interestingly, we
firstly demonstrated a successful transduction of MDC1C
63 We
firstly demonstrated that homology profiling of the 5'-U
64 In conclusions,our study
firstly demonstrated that salivary total alpha-synuclein
65 ferrocene (AFC), as electroactive probes was
firstly demonstrated, where the probes could be directly
66 n vacancies for charge compensation has been
firstly demonstrated.
67 Here we
firstly describe a case of an adult 33-year-old Caucasia
68 We
firstly designed an electrochemical system for dealloyin
69 Herein, we
firstly determined the role of CpG methylation in the re
70 The AuNP-GSH-FITC fluorescent probe was
firstly developed and used for bisulfide detection in bu
71 s, the comprehensive similarity measures are
firstly developed to calculate similarity for drugs and
72 , enniatins, beauvericin and zearalenone was
firstly developed.
73 This approach is powerful because,
firstly,
differences between in vitro and in vivo effect
74 We sought to answer two questions:
Firstly,
do dogs display specific discriminatory facial
75 (RR) of Rh flux to N fertilization decreased
firstly during growing season, increased in nongrowing s
76 that particle exchange occurs by two routes:
firstly,
during a period of unbridging and rebridging wh
77 al production but their prudent use requires
firstly eliminating any fertilizer mismanagement plus th
78 porous Au@Pd core-shell nanostructures were
firstly employed as the nanocarrier for the immobilizati
79 scle samples from Spanish dry-cured ham were
firstly evaluated for various physicochemical parameters
80 Firstly,
even with a perfectly known phylogeny, ancestra
81 The sensor performance was
firstly examined with tap water at varying DO levels.
82 tumor necrosis factor alpha (TNF-alpha) was
firstly experimentally validated in molecular and cellul
83 M), an electrochemical machining method, was
firstly exploited in constructing dimples with various p
84 Serum metabolic profiles were
firstly explored between 30 AIS patients and 31 healthy
85 rid organic-inorganic formed films here were
firstly exposed to atmospheres containing methylamine va
86 Firstly,
exposure to dim nocturnal illumination (<0.1 lu
87 f K562 cells to etoposide-induced apoptosis;
firstly failure of Bax targeting to mitochondria and, se
88 Firstly FastNCA is compared to NCA and NCA-r using synth
89 Firstly,
Fel d 1 on VLPs showed a strongly impaired abil
90 Firstly,
fixed-abrasive lapping is used to machine the M
91 ball of high temperature and pressure occurs
firstly,
followed by the micro-explosions on the (210) s
92 Firstly,
four methods (CADD, PolyPhen-2, SIFT, and SNAP2
93 Firstly,
gas chromatography was employed to analyze fatt
94 Firstly,
genome analysis has revealed the great diversit
95 Firstly,
glia are required for growth cone guidance, alt
96 Firstly,
glucose and macronutrient intake causes oxidati
97 Firstly,
glutamate substitution at Kir6.2 residue F168 g
98 One can now ask,
firstly,
how a host cell or organism 'sees' a microbial
99 Firstly,
how best should the [Formula: see text] be mode
100 Firstly,
Hpo promotes DIAP1 phosphorylation, likely decr
101 Firstly,
human umbilical endothelial cells (HUVECs) and
102 Firstly, (
i) chick mass was negatively associated with e
103 ratrol with higher antioxidant activity, was
firstly identified and quantified in GPE of the cv. Malb
104 MusaPIP2;6 was
firstly identified based on comparative analysis of stre
105 Here we
firstly identify the numbers of HSCs in various organs a
106 Firstly,
if a vernier stimulus is flashed for a short ti
107 to-terminated peptide nucleic acid (PNA) was
firstly immobilized onto gold electrode and used as the
108 lated peptide nucleic acid (PNA) probes were
firstly immobilized onto gold electrode through the form
109 e 221-residue IkappaB* protein were assigned
firstly in a smaller construct consisting of ankyrin rep
110 second phase at neurula and tailbud stages,
firstly in two symmetric patches near the posterior end
111 reover, considerable progress has been made,
firstly,
in disabling HSV vectors so as to prevent the d
112 Firstly,
in striking similarity to the common BRAF fusio
113 ng angles of water droplets on those dimples
firstly increased and then stabilized at a certain value
114 The increase of incubation temperature
firstly increased the lipid oxidation in krill oil and s
115 Firstly,
inhibition of neurons in the PeH abolished the
116 Firstly,
interference due to thickness-shear vibration m
117 The present study
firstly introduces the new conception of utilizing safe
118 This qualitative approach
firstly involves an ideas gathering survey that, once di
119 borne encephalitis virus (TBEV) complex, was
firstly isolated from Ixodes granulatus ticks in Malaysi
120 Firstly it contains two sizeable insertions compared to
121 Firstly,
it discusses and argues why visual based interv
122 a significant impact on cellular senescence:
Firstly,
it has been established that telomere shortenin
123 Firstly,
it has facilitated the detection of endogenous
124 Firstly,
it interacts with the RNAP and induces the open
125 Firstly,
it is responsible for the creation of genetic v
126 Firstly,
it presents a complete toolbox for simultaneous
127 Firstly,
it prevented the irreversible light-induced clo
128 With DOMs concentrations increasing, alpha
firstly kept constant, then sharply declined, and finall
129 Firstly,
manipulation of Rab5 expression results in co-o
130 To investigate this possibility, we
firstly mapped, in vitro, the sequence-dependent positio
131 cells (trophoblasts) in the human placenta:
firstly,
maternal immune and endothelial cells juxtapose
132 To do so, melatonin levels were
firstly measured in eyecups and plasma to determine circ
133 Firstly,
metal ion A may assist nucleophilic attack by m
134 Firstly ModFOLD, which is a fast Model Quality Assessmen
135 e have identified two subgroups of patients;
firstly,
MP with stable and characteristic radiologic ch
136 Firstly,
multiplex PCR analysis indicated that the novel
137 Firstly,
MutY possesses an exo-site that serves as a dec
138 Firstly,
negative holding potentials reduced inward curr
139 Firstly,
NiO-FET was tested for NADH detection showing a
140 n, we propose a term alignment method, which
firstly obtains translation candidates for each componen
141 eptors can potentially enhance cognition by,
firstly,
offsetting losses of glutamatergic synapses; se
142 Firstly,
oil stability was optimised by comparing the ac
143 egies to combat bacterial biofilms, focusing
firstly on small molecule interference with bacterial co
144 Firstly,
operational criteria now exist for prodromal or
145 Firstly,
over-expression of xRXR beta with xRAR alpha re
146 Firstly,
PAR-2 is expressed in the outer nucleated layer
147 Firstly,
PAR-immunized Ab-deficient (muMT) strain mice s
148 Firstly,
parental nucleosomes segregate to replicated DN
149 Firstly,
patient fibroblasts displayed a significant red
150 We
firstly performed in vitro analysis showing the expressi
151 We conclude that
firstly,
Pgp is not a swelling-activated Cl- channel; se
152 Firstly,
platelets were isolated from systemic venous bl
153 ocotrienol microcapsules (TM) were formed by
firstly preparing Pickering emulsion containing tocotrie
154 Firstly,
principal component analysis was carried out in
155 endent roles during pituitary morphogenesis;
firstly,
promotion of progenitor proliferation, and subs
156 In this study, we
firstly proposed network analysis by integrating data fr
157 opy (HRTEM) observations, this investigation
firstly provides the direct experimental evidence for th
158 rimental observation of triplet synchrony is
firstly realized in three coupled nonidentical mechanica
159 a strategy by which sites of latent HCMV can
firstly recruit CD4(+) T cells and then inhibit their an
160 ypes of regions by machine-learning methods:
firstly,
regions with active or inactive binding; second
161 The trial data were analysed in two ways:
firstly replicating the trial reported cohort analysis a
162 Here, we thoroughly analyze and
firstly report the flexoelectric effect in in-plane swit
163 ween localized and continuum states that was
firstly reported for atomic physics and solid-state quan
164 rial prey, a process previously suggested to
firstly require flagellar motility and then flagellar sh
165 n H7N9 infected patients is dramatic and was
firstly revealed in species level due to deep sequencing
166 s applied in cancer theranostic systems were
firstly reviewed, followed by analyzing pros and cons of
167 Firstly,
RNA-seq data from five tissues and seven develo
168 Conformations are
firstly sampled at glob level where each glob represents
169 The core samples are
firstly scanned to produce grayscale slices, and the cor
170 Firstly,
selective activation of EPAC in human umbilical
171 Thiolated PNA molecules are
firstly self-assembled onto gold electrode surface for t
172 Firstly,
separate introduction of a p53 defect into A278
173 The novelty of our analysis is that,
firstly,
sequence comparisons to/between both annotated
174 Firstly,
SeqUnwinder is able to unravel sequence feature
175 Firstly,
showing that stem cells can become tumours rais
176 Firstly,
SHP-1 binds to and negatively regulates signall
177 Firstly,
smn germline clones phenocopy mutations for two
178 Firstly,
specific inserts and extension added to the cor
179 Firstly,
spectral and quality parameters matrices were p
180 Firstly,
SpOrc1, SpOrc4 and SpOrc5, like those from othe
181 Our study leads to three conclusions:
Firstly,
support vector machines successfully separate p
182 nolin-5-yl) diazenyl] benzoic acid (QAN) was
firstly synthesized and characterized as a new chelating
183 This study
firstly tackles the direct measurement of the tensile pr
184 In this review, we
firstly take a look at techniques developed to 'wire-up'
185 abs play a dual role in regulation of OCRL1,
firstly targeting it to the Golgi apparatus and endosome
186 e lead SNPs from these 16 loci reported, and
firstly tested their associations in 1,248 patients with
187 Here, we show
firstly that ADCY5 mRNA expression in islets is lowered
188 These data suggest
firstly that caution should be used in interpretation of
189 Our data show
firstly that charge-neutralising mutations in S4 alter t
190 rpesvirus 6 (HHV-6) encephalitis recognizing
firstly that HHV-6A and HHV-6B are separate species with
191 n of Ag43 expression is therefore unusual in
firstly that OxyR binding at agn43 is dependent on the m
192 We show
firstly that the magnitude of the complex shear modulus
193 Our results indicate
firstly that while TnC has only small effects on the glo
194 vity selection using the comparative method:
firstly,
that a reduction of extrinsic mortality in soci
195 We found,
firstly,
that laminar flow fails to overcome the inflamm
196 Our principal findings are twofold:
firstly,
that oligomers of RANTES can cross-link envelop
197 ng a variety of labelling procedures we show
firstly,
that radial intercalation occurs in the gut tra
198 We conclude,
firstly,
that somatosensory driven precision grip respon
199 Firstly,
that spatial signaling via astrocytes can relay
200 Functional studies indicate,
firstly,
that the susceptible and protective HLA class I
201 Our results show,
firstly,
that while the leucine-zipper motif at the N te
202 into its intermediate phenotypes, which are
firstly the immune-mediated resistance and secondly the
203 udied on a dataset of 668 fish and shellfish
firstly the impact on their FA and TL content per 100g E
204 s, which is broken down into two key stages;
firstly the interaction between the host and the parasit
205 ole in susceptibility to systemic sclerosis;
firstly the maintenance of immune tolerance via genes on
206 Firstly,
the ability of sessile cells to actively mediat
207 Firstly,
the analysis of contiguous genome segments acro
208 Firstly,
the antiproliferative effects of celecoxib were
209 Firstly,
the brain or any sensorimotor system has time-d
210 Firstly,
the cell needs to specify a location at which t
211 Firstly,
the effect of the type of CD on the encapsulati
212 Firstly,
the effects of mixtures composed of up to 17 es
213 Firstly,
the effects on historical crop yields of improv
214 Firstly,
the first genome-wide association study in epil
215 Firstly,
the gold surface of SPR chip was modified with
216 Firstly,
the immediate inactivation of Listeria, Salmone
217 Firstly,
the inhibitory effect of NO3(-) is significantl
218 Firstly,
the periportal zonation of both glycogen syntha
219 Firstly,
the phase diagram of the system was established
220 ate the study of selection in viral genomes:
Firstly,
the presence of genes in overlapping reading fr
221 Firstly,
the procerebrum directly participates in distri
222 Firstly,
the questionnaire design and development phase
223 Firstly,
the RGO-AuNPs modified screen printed electrode
224 Recent studies emphasize
firstly,
the role of inflammatory cytokines, such as IL-
225 The findings suggest that,
firstly,
the subthalamic nucleus is involved in the prep
226 Firstly,
the switches are activated by a nucleic acid-cl
227 Firstly,
the t-force acting on the doublets near the swi
228 Firstly,
the target input must be differentiated from di
229 Firstly,
the time required for significant increases in
230 tion and treatment using bNAbs are reviewed:
firstly,
the use of sequential immunogens to activate B
231 Firstly they are important pigments influencing customer
232 Firstly,
they constitute separately unconventional appro
233 Firstly,
this article reviews and addresses the extracti
234 Firstly,
this is achieved by mediating B-cell tethering,
235 Firstly,
this is because funders require evidence of ret
236 Firstly,
this paper proposes a non-uniform evolving hype
237 Firstly,
this procedure provides a means to clarify the
238 We show that,
firstly,
this protein influences hindlimb outgrowth by r
239 propose that cGMP increases CBF in two ways:
firstly through a Ca2+-independent mechanism involving P
240 ichiometries like RuN3 and RuN4 are proposed
firstly to be thermodynamically stable, and the dynamica
241 The objective of this study was
firstly to describe the frequency of detection of allerg
242 te ethical assessment procedure is in place,
firstly to ensure patient safety and secondly to prevent
243 The aim of this study was
firstly to evaluate the effect on bioaccessibility of th
244 Firstly,
to assess the effect of N(2)O on the induction
245 The aims of this study were
firstly,
to compare perceived food intolerance in a grou
246 Firstly,
to delay treatment sentences the patient to pro
247 Firstly,
to examine the effects of CART peptide on hypot
248 Firstly,
two sessions of restraint were introduced, 20 m
249 This allowed,
firstly,
unravelling of the network of active central pa
250 Firstly,
urine specimens from 300 female military recrui
251 We
firstly use comparisons of experiments with heterologous
252 ty as ion-exchangers to the hybrid material,
firstly used for the in situ synthesis of the highly dis
253 re, a non-organic spray drying technique was
firstly used to prepare nanoporous mannitol with small a
254 proach to make vGWAS applicable to diseases:
firstly using a mixed model approach to partition dichot
255 Firstly,
using a genetic approach, we find no evidence t
256 Firstly,
using synthetic data, we identified experimenta
257 Firstly,
validation of the approach was performed by cor
258 Firstly,
various methods for printing graphene-based flu
259 Firstly,
VDR outcompetes NFAT1 for binding to the compos
260 sentation and to compare mean visual loss of
firstly versus secondly affected eyes.
261 gest a set of principles: evolution proceeds
firstly via pathways subject to negative regulation, the
262 y, we used immunohistochemical techniques to
firstly,
visualize and quantify the STN neurochemical or
263 Firstly,
vocabularies are shown to evolve on a cultural
264 Firstly,
wavelets are used to smooth G+C profiles to loc
265 Firstly we demonstrate that spatial variations in spore
266 Firstly we show that the constitutive hdm2-P1 promoter i
267 This procedure involves two steps;
firstly,
we assign the binding of particular ligands to
268 Firstly,
we characterised 136 Vlambda rearrangements (59
269 Firstly,
we characterize ATR-Seckel cells for their resp
270 Firstly,
we characterized and optimized the endogenous t
271 Firstly,
we characterized the murine cKit(+) cells prese
272 Firstly,
we confirm that Sls-GFP can be used in the hete
273 Firstly,
we confirmed that the transgenic technique resu
274 Firstly,
we created viable mutant alleles of NBP35 in Ar
275 Firstly,
we demonstrate that alterations in digit develo
276 Firstly,
we demonstrate that the disruption of KLB entir
277 Firstly,
we derive constraints under which classes of sp
278 Firstly,
we established an acute treatment protocol and
279 Firstly,
we estimated in mice with acute fibrogenesis in
280 Firstly,
we estimated the causal effect of maternal vita
281 Firstly,
we fitted an age-structured susceptible-infecti
282 Firstly,
we found that the likelihood of scratching was
283 Firstly,
we found that there is an mGlu2 component to th
284 Firstly,
we have found that the previously identified he
285 Firstly,
we identify endogenous retroviral fossils in ma
286 Firstly,
we investigate the performance of a widely used
287 Firstly,
we investigate the plasticity of a class II maj
288 Firstly,
we investigate the sensor response to target DN
289 Firstly,
we made a systematic comparison of the expressi
290 Firstly,
we observed a reduction in ubiquitinated protei
291 Firstly,
we performed meta-analysis on a gene expression
292 Firstly,
we provided putative cofactors/collaborators an
293 Firstly,
we show that in breast cancer patients the pro-
294 Firstly,
we show that on the liability scale, common var
295 Firstly,
we show that periodic calcium waves in ASMC, as
296 Firstly,
we study the intensity dependence of LIAD by fi
297 Firstly,
we tested for an interaction effect on growth r
298 Firstly,
we used regulatory interactions manually curate
299 We validate PFClust
firstly with reference to a number of synthetic datasets
300 ntibody anti-E. coli serotype O55 and tested
firstly with saline and then with bacterial concentratio