ライフサイエンスコーパス: flagella

1 surfaces by rotating long appendages called flagella.

2 orylation-related assembly of RSs and entire flagella.

3 the predominant protein transport system in flagella.

4 f swimming microorganisms with front-mounted flagella.

5 r-prone Escherichia coli strain lacks mature flagella.

6 complex in unicellular organisms bearing few flagella.

7 significantly reduced or elevated in d1blic flagella.

8 major structural distinctions from bacterial flagella.

9 ing sperm completely lack or have very short flagella.

10 promoted slow assembly of nearly full-length flagella.

11 ve despite many cryo-ET studies of cilia and flagella.

12 f the pellicle but only in strains that have flagella.

13 ent did not occur with G7 bacteria devoid of flagella.

14 hat is nonmotile but retains its periplasmic flagella.

15 but is not required for, tubulin entry into flagella.

16 transport (IFT) system for assembly of their flagella.

17 onal structure of the N-DRC in Chlamydomonas flagella.

18 cargos, such as SPAG16L, to build the sperm flagella.

19 ns in filamentous microtubules and bacterial flagella.

20 otile cilia as compared to primary cilia and flagella.

21 ting spermatid that directs formation of the flagella.

22 almitoylation, targets proteins to cilia and flagella.

23 sulted in aggregates of stalled IFT-B in the flagella.

24 n but not the maintenance of mammalian sperm flagella.

25 tive assembly, structure, or function of the flagella.

26 re 1.5- to 2.0-mum swimmer cells with 4 to 6 flagella.

27 generated by the nanometers-thick bacterial flagella.

28 s that organize signaling proteins along the flagella.

29 nalogously to swarmer cells in bacteria with flagella.

30 rray that is essential to template cilia and flagella.

31 ct the reciprocal expression of adhesins and flagella.

32 e number and average rotational state of its flagella.

33 ired for elongation and maintenance of sperm flagella.

34 (T3SS) and overexpression of non-functional flagella.

35 havior is only weakly dependent on number of flagella.

36 ole in coordinating the beating of cilia and flagella.

37 s from IFT trains at the tip and diffuses in flagella.

38 pecies swim by rotating single polar helical flagella.

39 re at the tips of both assembling and mature flagella.

40 mutant strains of Bacillus subtilis lacking flagella.

41 ingle IFT trains and motors in Chlamydomonas flagella.

42 ate, where faster growing cells produce more flagella.

43 tion and maintenance of eukaryotic cilia and flagella.

44 t support transport of outer arm dynein into flagella.

45 ion negatively correlates with the length of flagella.

46 FT-B proteins, and assembles only very short flagella.

47 lar trafficking, and templating of cilia and flagella.

48 functions, including signaling in cilia and flagella.

49 with the bending waveforms of Chlamydomonas flagella.

50 esistance in these immobilized Chlamydomonas flagella.

51 er with a description of the movement of the flagella.

52 oves cargo from the basal body to the tip of flagella [1].

53 d morpholino depletion of axonemal Paralyzed Flagella 16 indicated that flagella-based forces initiat

54 creased recruitment in rapidly growing short flagella [2].

55 dy and the inner dynein arm complexes within flagella [3, 4].

56 At the base of the bacterial flagella, a cytoplasmic rotor (the C-ring) generates tor

57 our knowledge, into the beating mechanism of flagella and a powerful tool for future studies.

58 astigote forms produces cells with long free flagella and a shorter FAZ, accompanied by repositioning

59 eruginosa aggregates that required bacterial flagella and a type III secretion system apparatus.

60 his pathway is employed for glycosylation of flagella and autotransporters.

61 r data sets related to the cell cycle and to flagella and basal bodies and to assign isoforms of dupl

62 and processes, including cell cycle control, flagella and basal bodies, ribosome biogenesis, and ener

63 s photosynthesis and chloroplast biogenesis, flagella and basal body structure/function, cell growth

64 The motion of flagella and cilia arises from the coordinated activity

65 eramide-mediated translocation of pYGSK into flagella and cilia is an evolutionarily conserved mechan

66 led to GSK3 dephosphorylation and defective flagella and cilia.

67 key determinant of normal orientation of the flagella and collar assembly.

68 rform micromanipulation on configurations of flagella and conclude that a mechanism, internal to the

69 ines are evolutionarily related to bacterial flagella and consist of a large cytoplasmic complex, a t

70 is unknown how cells recognize the length of flagella and control IFT.

71 specific PRMTs and their target proteins in flagella and demonstrate that PRMTs are cargo for transl

72 assembly and function of mammalian cilia and flagella and establishes the gene-trapped allele as a ne

73 ization, requiring adherence factors such as flagella and fimbriae.

74 These PRMTs localize to the tip of flagella and in a punctate pattern along the length, ver

75 c interaction between E. coli H7, H6 and H48 flagella and ionic lipids in plant plasma membranes.

76 e, the causative agent of cholera, use their flagella and mannose-sensitive hemagglutinin (MSHA) type

77 pYGSK3) at the base and tip of Chlamydomonas flagella and motile cilia in ependymal cells.

78 nce of filaments, significantly thinner than flagella and often bundled, associated with cell surface

79 cally mediated by surface structures such as flagella and pili, followed by a permanent adhesion stag

80 or the biogenesis and stability of cilia and flagella and play important roles in metazoan developmen

81 hypothesis to explain dynein coordination in flagella and provide a mathematical foundation for compa

82 in Chlamydomonas by myriocin led to loss of flagella and reduced tubulin acetylation, which was prev

83 We speculate that a large number of flagella and the absence of a periplasm make B. subtilis

84 transcriptionally modulates biosynthesis of flagella and the iron chelator ICDH-Coumarin whose produ

85 an animal model of CDI, a synergic effect of flagella and toxins in eliciting an inflammatory mucosal

86 ted by its motility, and appendages known as flagella and type IV pili (TFP) are known to confer such

87 ls that interacted with each other via their flagella and underwent fusion, as visualized by the mixi

88 subtilis (wild-type and a mutant with fewer flagella), and a motile Streptococcus (now Enterococcus)

89 hogen-associated molecular patterns, such as flagella, and increasing resistance to host immune molec

90 the physiological events occurring in cilia, flagella, and microvilli are of fundamental importance f

91 II (DNA binding and bending) proteins, pili, flagella, and outer membrane vesicles.

92 acterial virulence such as toxins, adhesins, flagella, and pili, among others.

93 --which define the shape of axons, cilia and flagella, and provide tracks for intracellular transport

94 are also highly enriched at the base of the flagella, and the basal localization of these PRMTs chan

95 ues are also enriched at the tip and base of flagella, and their localization also changes during fla

96 swimming and swarming motilities powered by flagella, and twitching motility powered by Type IV pili

97 Some bacterial functions (for example, flagella- and chemotaxis-associated) were systematically

98 d the odds of seroconversion of IgG S. Typhi flagella antibody (adjusted OR 6.4, 95% CI, 1.3-31.4; P

99 with circulating strains expressing diverse flagella antigens including Hj, Hd and Hz66.

100 S. Typhi strains expressing the Hj, Hd, Hz66 flagella antigens.

101 Cilia and flagella are assembled and maintained by the motor-drive

102 Cilia/flagella are assembled and maintained by the process of

103 Cilia and flagella are assembled by intraflagellar transport (IFT)

104 Cilia and flagella are conserved, motile, and sensory cell organel

105 Flagella are crucial for bacterial motility and pathogen

106 Flows generated by ensembles of flagella are crucial to development, motility and sensin

107 Flagella are extracellular organelles that propel bacter

108 Cilia and flagella are microtubule-based organelles that protrude

109 Cilia and flagella are model systems for studying how mechanical f

110 Flagella are multiprotein complexes necessary for swimmi

111 In the absence of FliD, flagella are not formed, resulting in impaired motility

112 Bacillus subtilis flagella are not only required for locomotion but also a

113 ATEMENT How processes occurring in cilia and flagella are powered is a matter of general interest.

114 Flagella are required for biofilm formation, as well as

115 Cilia and flagella are simple organelles in which a single measure

116 Motile cilia and flagella are whiplike cellular organelles that bend acti

117 Cilia (eukaryotic flagella) are present in diverse eukaryotic lineages and

118 For thin flagella, as the channel radius decreases, forward veloc

119 on systems (T2SS), type 4 pili, and archaeal flagella assemble fibres from initially membrane-embedde

120 is, ATP-binding cassette (ABC) transporters, flagella assembly and bacterial chemotaxis, as well as f

121 lack of IFT74 destabilized IFT-B, leading to flagella assembly failure.

122 ium, therefore, suggested a possible role in flagella assembly in male gametes, the only flagellated

123 ent necessary for motile cilium function and flagella assembly.

124 -glycosylation of flagellins is required for flagella assembly.

125 evolutionarily conserved protein, cilia- and flagella-associated protein 69 (CFAP69), in mice that re

126 assembly of dynein arm motors into cilia and flagella axonemes.

127 The number and location of flagella, bacterial organelles of locomotion, are specie

128 xonemal Paralyzed Flagella 16 indicated that flagella-based forces initiated daughter cell separation

129 These spirochaetes employ an unusual form of flagella-based motility necessary for pathogenicity; ind

130 and other odorant ligands robustly activate flagella beating in an Orco-dependent process.

131 Fluid forces are sufficient to keep flagella beating in synchrony.

132 reported here, which include measurements of flagella bundle orientation and cell tracking in the sel

133 No known cyanobacterium is equipped with flagella, but a diverse range of species is able to 'gli

134 e study of bacterial pathogens with sheathed flagella, but also raises important biophysical question

135 Deletion of polar flagella, but not the lateral flagella, can dramatically

136 ed IFT-B levels and enabled growth of longer flagella, but the flagella lacked outer dynein arms.

137 hat PRMTs are cargo for translocation within flagella by the process of IFT.

138 Although they lack flagella, C. perfringens bacteria can still migrate acro

139 pport for 25 came from the observation that flagella can assemble and rotate when FliG is geneticall

140 lower viscosity than the cell body, so that flagella can be seen as nano-rheometers for probing the

141 effect of the active thrust generated by the flagella can be singled out.

142 Indeed, by activating the TLR5, flagella can elicit activation of the MAPK and NF-kappaB

143 Vibrio parahaemolyticus, we found that polar flagella can reduce the phage infectivity.

144 etion of polar flagella, but not the lateral flagella, can dramatically promote the adsorption of pha

145 Bacterial flagella change their helical form in response to enviro

146 enes and class II and III (but not I) of the flagella-chemotaxis regulon.

147 the axoneme central apparatus, and regulates flagella/cilia motility.

148 This finding suggests a model in which flagella compete with cytoplasmic microtubules for a fix

149 oaches to identify seven constituents of the flagella connector at the tip of an assembling trypanoso

150 ation and functional studies reveal that the flagella connector membrane junction is attached to the

151 establishing cell morphology, including the flagella connector, flagellum attachment zone, and bilob

152 is revealed pseudaminic acid residues on the flagella contributed to DC IL-10 expression.

153 cally, how the rotational states of a cell's flagella cooperatively determine whether the cell 'runs'

154 Contrary to flagella-dependent migration modes like swarming, we sho

155 6) also play an important role in regulating flagella-dependent motility, which allows cells to rapid

156 Efficient motile function of cilia and flagella depends on coordinated interactions between act

157 The construction of cilia and flagella depends on intraflagellar transport (IFT), the

158 The assembly of cilia and flagella depends on the activity of two microtubule moto

159 tal morphology and motility, the periplasmic flagella display no additional properties related to imm

160 In this model, the absence of flagella dramatically decreases the degree of mucosal in

161 Swarming motility is a flagella-driven multicellular behaviour that allows bact

162 bacterium Pseudomonas fluorescens that lack flagella due to deletion of the regulatory gene fleQ.

163 ed for sufficient entry of IFT material into flagella during assembly.

164 CD6) was enriched in ectosomes released from flagella during gamete activation.

165 ystem that transports proteins to the tip of flagella during growth.

166 Our comprehensive screens showed which flagella elements are essential for growth and which are

167 tein EB1 is present at the tips of cilia and flagella; end-binding protein 1 (EB1) remains at the tip

168 ively transported flagellar proteins to grow flagella even with extremely infrequent or no ATP hydrol

169 Eukaryotic cilia/flagella exhibit two characteristic ultrastructures refl

170 Flagella exist in all eukaryotic phyla, but neither the

171 The flagella export AAA+ ATPase FliI was identified as a res

172 at cytoplasmic microtubules can compete with flagella for a limited tubulin pool, showing that altera

173 cking the rotary motion of helical bacterial flagella for propulsion, and are often composed of monol

174 an exchange with unbleached EB1 entering the flagella from the cell body.

175 Primary and motile cilia/flagella function as cellular antennae, receiving signal

176 ae, a rod-shaped bacterium devoid of pili or flagella, glide over glass at speeds of 2-4 mum/s [1].

177 body fluids and molecules, motile cilia and flagella govern respiratory mucociliary clearance, later

178 ic phyla, but neither the mechanism by which flagella grow nor the conservation of this process in ev

179 Defects in flagella growth are related to a number of human disease

180 Ectosomes released from flagella have a unique protein composition, being enrich

181 In particular, the roles of flagella have been studied in multiple solid-surface bio

182 n mutant of B. dolosa to examine the role of flagella in B. dolosa lung colonization.

183 h has also elucidated a more complex role of flagella in C. difficile virulence pertaining to the reg

184 The flagella in Chlamydomonas ndk5 mutant were paralyzed, al

185 CrSEPT was detected at the base of the flagella in Chlamydomonas, suggesting that CrSEPT is inv

186 eased research into the role of C. difficile flagella in colonisation and adherence.

187 ights into the specific role of C. difficile flagella in colonisation and toxin gene expression.

188 highlight the important role of C. difficile flagella in eliciting mucosal lesions as long as the tox

189 essential for the correct function of sperm flagella in mice and play a role in polyglutamylation of

190 unlike that of well-studied motile cilia and flagella in protists, such as Paramecia and Chlamydomona

191 mics of Ca(2+) elevations in the cytosol and flagella in response to salinity and osmotic stress.

192 m dynein, also fails to be imported into the flagella in the absence of the IFT46 N-terminus.

193 Here we report a role for flagella in the regulation of the K-state, which enables

194 t shear stiffness of wild-type Chlamydomonas flagella in vivo, rendered immotile by vanadate, to be E

195 lmonella can move on 0.3% agarose media in a flagella-independent manner when experiencing the PhoP/P

196 o flat curves, and have 10 to 14 periplasmic flagella inserted at each cell end.

197 TLR5 driven pro-inflammatory axis, C. jejuni flagella instead promote an anti-inflammatory axis via g

198 Escherichia coli H7 flagella interacted with a sulphated carbohydrate (carra

199 nd to Arabidopsis thaliana, was dependent on flagella interactions with phospholipids and sulpholipid

200 transition zone (TZ) of eukaryotic cilia and flagella is a structural intermediate between the basal

201 The bending of cilia and flagella is driven by forces generated by dynein motor p

202 The motility of cilia and flagella is driven by thousands of dynein motors that hy

203 nonmotile flaB mutant that lacks periplasmic flagella is rod shaped and unable to infect mice by need

204 The periodic bending motion of cilia and flagella is thought to arise from mechanical feedback: d

205 tility, which is provided by its periplasmic flagella, is critical for every part of the spirochete's

206 he dynamics of physically separated pairs of flagella isolated from the multicellular alga Volvox has

207 Archaea use flagella known as archaella-distinct both in protein com

208 d enabled growth of longer flagella, but the flagella lacked outer dynein arms.

209 uno-electron microscopy reveal that ODA10 in flagella localizes strictly to a proximal region of doub

210 Bacterial flagella mediate host-microbe interactions through tissu

211 escribe the molecular mechanism underpinning flagella-mediated adherence to plant tissue for the food

212 In Salmonella enterica serovar Typhimurium, flagella-mediated motility is repressed by the PhoP/PhoQ

213 However, flagella might remain in OMV pellets following OMV purif

214 We show that flagella motility, Rab11, and actin coordination are nec

215 Before their import into cilia and flagella, multi-subunit axonemal dynein arms are thought

216 In the case of cilia and flagella, multiple cell biological studies show that mic

217 While mutant cells with only polar flagella navigate by a "run-reverse-flick" mechanism res

218 d that the carbonic anhydrase CAH6 is in the flagella, not in the stroma that surrounds the pyrenoid

219 e OR coreceptor, AgOrco, is localized to the flagella of A. gambiae spermatozoa where Orco-specific a

220 We show that flagella of Chlamydomonas mutants deficient in filamenta

221 PRMTs are lost from the flagella of fla10-1 cells, which carry a temperature-sen

222 Motility and the number of flagella of H. pylori P12 wild-type were significantly h

223 Adherence of E. coli O157 : H-expressing flagella of serotype H7, H6 or H48 to plants associated

224 Cilia and flagella often exhibit synchronized behavior; this inclu

225 -flight" model, which measures the length of flagella on the basis of the travel time of IFT protein

226 lower expression of the fliC gene and lacked flagella on the cell surface.

227 cells, and this effect was dependent on the flagella only when bacteria were dead.

228 ltaneously feed is due to constantly beating flagella or appendages that are positioned either anteri

229 motilities that do not depend on traditional flagella or pili, but are powered by mechanisms that are

230 urfaces in the absence of appendages such as flagella or pili.

231 re capable of movement over surfaces without flagella or pili; they glide.

232 ive arrangement of axonemal microtubules and flagella outer dense fibers.

233 Even though DeltamotB bacteria assembled flagella, part of the mutant cell is rod shaped.

234 The conoid has been suggested to derive from flagella parts, but is thought to have been lost from so

235 ssary for pathogenicity; indeed, spirochaete flagella (periplasmic flagella) reside and rotate within

236 -shaped ends and the presence of periplasmic flagella (PF) with pronounced spontaneous supercoiling.

237 the role played by T. denticola periplasmic flagella (PF), unique motility organelles of spirochetes

238 cial film formation occurs in the absence of flagella, pili, or certain polysaccharides.

239 glide mysteriously on surfaces without using flagella, pili, or other external appendages.

240 These results support an emerging view that flagella play a central role in cell division among prot

241 is poorly understood, it has been shown that flagella play an important role in surface sensing by tr

242 o V. parahaemolyticus, indicating that polar flagella play an inhibitory role in the phage infection.

243 Motile cilia and flagella play critical roles in fluid clearance and cell

244 Hypothesizing that S. Typhi flagella plays a key role during infection, we construct

245 bacteria Vibrio fischeri when it rotates its flagella prompts its host, the Hawaiian bobtail squid, t

246 Flagella propel bacteria during both swimming and swarmi

247 to contribute to disease development, e.g., flagella, prophages, and salicylic acid hydroxylase.

248 The short flagella rarely have axonemes but assemble ectopic micro

249 Assembly of cilia and flagella requires intraflagellar transport (IFT), a high

250 xoneme, the structural scaffold of cilia and flagella, requires translocation of a vast quantity of t

251 y; indeed, spirochaete flagella (periplasmic flagella) reside and rotate within the periplasmic space

252 esion and motility, mediated by fimbriae and flagella, respectively, is essential for disease progres

253 Decreased IFT-A in these short flagella resulted in aggregates of stalled IFT-B in the

254 MotI-inhibited flagella rotated freely by Brownian motion, and suppress

255 These results indicated that polar flagella rotation is a previously unidentified mechanism

256 HAMP mutational phenotypes: those that cause flagella rotation that is counterclockwise (CCW) A and k

257 te's PF sheath, and a key determinant of the flagella's coiled structure.

258 Contrary to a hypothesised role in flagella, SAS6L was absent during gamete flagellum forma

259 uggest that this is due to the fast-rotating flagella seeing a lower viscosity than the cell body, so

260 psilon is quadrilaterally arranged along the flagella, similar to the CatSper complex in mouse sperm.

261 ellar correlations, an 'effective number' of flagella-smaller than the actual number-enters into this

262 lues in the range expected for Chlamydomonas flagella, solutions to the fully nonlinear equations clo

263 motility in Myxococcus xanthus is powered by flagella stator homologs that move in helical trajectori

264 d to abnormal cell morphologies and detached flagella, suggesting that eIF5A is important for transla

265 ule formation, LPS biosynthesis, chemotaxis, flagella synthesis and flagellin (-like) secretion, type

266 otation, not the physical presence, of polar flagella that inhibits the phage infection of V. parahae

267 timuli also induced Ca(2+) elevations in the flagella that occurred independently from those in the c

268 In bacterial flagella, the filament and the hook have distinct functi

269 Flagella, the helical propellers that extend from the ba

270 wimmer decreases as well; however, for thick flagella, there is an optimal radius of the channel that

271 opose that unlike the Salmonella Typhimurium flagella-TLR5 driven pro-inflammatory axis, C. jejuni fl

272 Adherence of purified H7 and H48 flagella to carrageenan was reduced at higher concentrat

273 rate time-irreversible deformations of their flagella to produce thrust.

274 EtpA interacts with the tips of ETEC flagella to promote bacterial adhesion, toxin delivery,

275 ms, it uses the breaststroke beat of its two flagella to pull itself forward [1].

276 of bacteria, oscillate or twist a hair-like flagella to swim.

277 s, supporting the functional contribution of flagella to the evolution of invasion machinery.

278 ein composition and structure from bacterial flagella-to drive cell motility, but the structural basi

279 ation of chemotaxis clusters adjacent to the flagella--to which the chemotactic signal is transmitted

280 Orientation of the flagella toward the cell body is critical for determinat

281 mechanisms, Jeffrey Orbit and shear-induced flagella unbundling, are responsible for the enhancement

282 sembly and speed were normal in dyf13 mutant flagella, unlike in other IFT complex B mutants.

283 nts of Ribbon proteins from sea urchin sperm flagella, using quantitative immunobiochemistry, proteom

284 ces in the phenotypic properties of S. Typhi flagella variation and how they impact on the pathogenes

285 that T. cruzi trypomastigotes discard their flagella via an asymmetric cellular division.

286 or merely the possession of the periplasmic flagella was crucial for cellular morphology and host pe

287 inst S. Typhi lipopolysaccharide (LPS) O and flagella was measured before and 28 days following immun

288 mice and the sole presence of toxins without flagella was not enough to elicit epithelial lesions.

289 ally occurring species with 4, 8, or even 16 flagella, we find diverse symmetries of basal body posit

290 Because HMW is absent from mature flagella, we propose that HMW is not a structural compon

291 lence of V. parahaemolyticus only when polar flagella were absent both in vitro and in vivo.

292 Intriguingly, ndk5's flagella were also short, resembling those of an allelic

293 In contrast, flagella were found to be dispensable for host cell adhe

294 Purified H7 flagella were observed to physically interact with plasm

295 so far been mostly found on motile cilia and flagella, where it is involved in the stabilization of t

296 The C. difficile flagella, which confer motility and chemotaxis for succe

297 ss of spermiogenesis is the formation of the flagella, which enables sperm to reach eggs for fertiliz

298 in wild-type cells, causing paralyzed short flagella with hypophosphorylated, less abundant, but int

299 tility, these bacteria consistently regained flagella within 96 hours via a two-step evolutionary pat

300 ion in which ejaculate contains mostly sperm flagella without heads.