ライフサイエンスコーパス: flagellum

1 lecules consumed per beat of a demembranated flagellum.

2 nsing, which involves the rotating bacterial flagellum.

3 s, which generates propulsive bending of the flagellum.

4 ticipate in the function of its single polar flagellum.

5 e-unit genome is physically connected to the flagellum.

6 l positions in addition to the primary polar flagellum.

7 alcium channel is activated in the mammalian flagellum.

8 usly detecting the rotational states of each flagellum.

9 e mitochondrial DNA to the basal body of the flagellum.

10 sion of flagellar genes with assembly of the flagellum.

11 anterior kinetoplast was associated with the flagellum.

12 model into oval amastigotes with no external flagellum.

13 t it can extend without impinging on the old flagellum.

14 d tmAC in the head and Adcy10 and PKA in the flagellum.

15 ng to detachment and release of the parasite flagellum.

16 e by an export machinery at the base of each flagellum.

17 s in terms of number and localization as the flagellum.

18 energy source in the channel of the external flagellum.

19 ting a GFP-fusion protein to the trypanosome flagellum.

20 les that help position the parasite's single flagellum.

21 rium or nanobot driven by a rotating helical flagellum.

22 hey equilibrate after amputation of a single flagellum.

23 es in different regions of the Chlamydomonas flagellum.

24 nteractions in the assembly of the bacterial flagellum.

25 e radial and longitudinal differences in the flagellum.

26 e origin, the chemotactic machinery, and the flagellum.

27 ial surface need not always be pushed by its flagellum.

28 ed the intrinsic beat frequency of the trans flagellum.

29 body, as well as detailed kinematics of the flagellum.

30 the filament, thereby extending the growing flagellum.

31 mouse sperm head and to the midpiece of the flagellum.

32 single-celled eukaryote with a single cilium/flagellum.

33 FliG in the cytoplasmic C ring rotor of the flagellum.

34 tokinesis by activating motility of the male flagellum.

35 is disrupted at 0.8 mum intervals along the flagellum.

36 us load experienced by the motor through the flagellum.

37 e junction to the microtubules in the mature flagellum.

38 forces that deform the cross-section of the flagellum.

39 ed in components of the cytoskeleton and the flagellum.

40 resulting from a buckling instability of the flagellum.

41 positioned close to the base of the swimming flagellum [4, 5], demonstrating this is a photoreceptive

42 For self-assembly of the bacterial flagellum, a specific protein export apparatus utilizes

43 Inhibition of the flagellum activates the DegS-DegU circuit to turn on bio

44 cialized cytoskeletal structure required for flagellum adhesion and cell morphogenesis.

45 gellum attachment zone filament assembly for flagellum adhesion and cytokinesis initiation.

46 The gp72 glycoprotein is associated with the flagellum adhesion zone on the parasite surface, and its

47 w abundance glycoprotein associated with the flagellum adhesion zone, called gp72.

48 is a cytoskeletal protein located within the flagellum along the flagellar attachment zone (FAZ).

49 d control of the rotational direction of the flagellum, anchored to the central transmembrane ring on

50 structures and led to detachment of the new flagellum and a small portion of the cytoplasm.

51 P1 by co-localization with antibodies to the flagellum and acidocalcisomes, respectively.

52 o key fungal characters in Opisthokonta, the flagellum and chitin synthases.

53 iation of IFT-A and IFT-B at the base of the flagellum and flagellar import of IFT-A.

54 hat of the functionally equivalent bacterial flagellum and flagellar motor.

55 PA2982 led to non-polar localization of the flagellum and FlhF, which was thought to sit at the top

56 carrying cargoes from the cell body into the flagellum and from the flagellum back to the cell body.

57 Although the flagellum and injectisome serve different purposes, they

58 is located in the sperm head rather than the flagellum and is controlled by intracellular pH, but not

59 We show that Slo1 is localized to the sperm flagellum and is inhibited by progesterone.

60 his article, the equations of motion for the flagellum and its doublets are derived from mechanical e

61 flagellum prevented entry of IFT-A into the flagellum and led to severely decreased IFT injection fr

62 itochondrial genome to the basal body of the flagellum and mediates the segregation of the replicated

63 retory and endocytic organelles but also the flagellum and nucleus.

64 s two types of motility structures, a single flagellum and one or two clusters of type IV pili, to th

65 te the holdfast synthesis machinery with the flagellum and pili.

66 rter FAZ associated with a longer unattached flagellum and repositioned kinetoplast and basal body, r

67 tomonad can either remain attached or grow a flagellum and resume swimming.

68 , a freshwater bacterium, has a single polar flagellum and stalk.

69 Cb13 and CbK actively interact with the flagellum and subsequently attach to receptors on the ce

70 roteins sufficient to assemble a half-length flagellum and that assembly of full-length flagella requ

71 clude that there are multiple ways to form a flagellum and that species-specific structural knowledge

72 nts including the basal bodies that seed the flagellum and the flagellar pocket collar that is critic

73 a demonstrate that surface attachment by the flagellum and the flagellar pocket, a Leishmania-like fl

74 ternal cellular projections: the hook of the flagellum and the injectisome needle.

75 more detailed model incorporating a helical flagellum and the rotational degrees of freedom of the c

76 embly of multiprotein complexes, such as the flagellum and the stalk and the correct positioning of r

77 ctor at the tip of an assembling trypanosome flagellum and three constituents of the axonemal capping

78 he GDP-locked version is unable to enter the flagellum and to interact with other IFT-B proteins and

79 ellum distinguish it from both the bacterial flagellum and type IV pili.

80 ed in the cytoplasm, reaches the base of the flagellum, and associates with the IFT machinery in a ma

81 motors generate sliding forces that bend the flagellum, and bending leads to deformations and stresse

82 m attachment zone filament, detached the new flagellum, and caused defective cytokinesis.

83 had a short, wide body, a very long anterior flagellum, and either one or two kinetoplasts, but only

84 g forces, regulation by the curvature of the flagellum, and regulation by the normal forces that defo

85 the machinery used to assemble the bacterial flagellum, and the needle complex many Gram-negative pat

86 onal degrees of freedom of the cell body and flagellum, and we use numerical simulations to map out t

87 s in the midpiece and principal piece of the flagellum are distinctively different.

88 anism of this remodeling and the fate of the flagellum are obscure.

89 3 secretion system (T3SS) and the bacterial flagellum are related pathogenicity-associated appendage

90 Here we identify the B. subtilis flagellum as a mechanosensor that activates the DegS-Deg

91 nsight into the versatility of the bacterial flagellum as a secretory machine that can export protein

92 Vibrio, Proteus and Caulobacter that use the flagellum as a surface sensor.

93 ral processing role for TbRP2 in trypanosome flagellum assembly and challenge the notion that TbRP2 f

94 lar processes, including envelope integrity, flagellum assembly and protein quality control.

95 nemes, or general vesicular trafficking in a flagellum assembly context.

96 arasites have no apparent defects in growth, flagellum assembly, motility or differentiation in vitro

97 on apparatus may be derived from flagella or flagellum associated structures.

98 retion proteins (PopD, PcrV, and ExoS) and a flagellum-associated protein (FliD).

99 ms along magnetic field lines using a single flagellum at each cell pole.

100 Marine bacteria often swim with a single flagellum at high speeds, alternating "runs" with either

101 transitions by regulating the length of the flagellum attachment zone (FAZ) filament, a specialized

102 rectionally from the anterior tip of the new flagellum attachment zone (FAZ) toward the posterior end

103 olecule entry into the FP and nucleating the flagellum attachment zone (FAZ), which adheres the flage

104 flagellum to the cell body, mediated by the flagellum attachment zone (FAZ).

105 role in promoting basal body segregation and flagellum attachment zone filament assembly for flagellu

106 ed basal body segregation, disrupted the new flagellum attachment zone filament, detached the new fla

107 and the flagellar pocket, a Leishmania-like flagellum attachment zone, and a Trypanosoma cruzi-like

108 orphology, including the flagella connector, flagellum attachment zone, and bilobe structure.

109 rement for the assembly and extension of the flagellum attachment zone, which adheres the flagellum t

110 ys multiple roles in basal body segregation, flagellum attachment, and cytokinesis.

111 he cell body into the flagellum and from the flagellum back to the cell body.

112 y a type III export machinery located at the flagellum base, after which subunits transit through a n

113 P) can be markedly more complex than related flagellum-based chemotaxis systems.

114 tics during the early stage of recovery; (2) flagellum-based motility in the mid to late stage of rec

115 Flagellum-based motility is considered to be critical fo

116 We confirm that flagellum-based motility is involved in, but is not abso

117 We report that flagellum-based motility similarly contributes to pellic

118 s work, we characterize the contributions of flagellum-based motility, chemotaxis and oxygen sensing

119 Further, we show that flagellum-based motility, chemotaxis and oxygen sensing

120 ium to Sal4 results in the immediate loss of flagellum-based motility, in alterations to the outer me

121 agellar rotation, accompanied by a decreased flagellum-based motility.

122 true for reductions in the wavenumber of the flagellum beat, but not universally so, emphasising the

123 ece, middle piece and principal piece of the flagellum between testicular and epididymal spermatozoa.

124 phodiesterase (EAL) domain to nucleate polar flagellum biogenesis.

125 ng the axoneme central pair apparatus and in flagellum biogenesis.

126 expression, encoding the master regulator of flagellum biosynthesis and chemotaxis, by stabilizing th

127 Mutants defective in the polar flagellum biosynthesis FliAP sigma factor also outcompet

128 erkinsela sp. has lost the ability to make a flagellum but retains hallmark features of kinetoplastid

129 egulates the length of both the T3SS and the flagellum, but the molecular basis for this length contr

130 of extending microtubules of the assembling flagellum by a kinesin-15 family member.

131 ivery of flagellin, the major subunit of the flagellum, by bacterial secretion systems.

132 ue to the rotation of the trailing (leading) flagellum can account for these observations.

133 tivation of multiple genes, including in the flagellum-chemotaxis pathway.

134 ctions in motility and the expression of the flagellum-chemotaxis regulon between these clinically re

135 While all sterols are enriched in the flagellum, cholesterol is especially enriched.

136 The distal end of the eukaryotic flagellum/cilium is important for axonemal growth and si

137 Each flagellum consists of a basal body, a hook, and a filame

138 The bacterial flagellum contains a specialized secretion apparatus in

139 Calcium in the flagellum controls sperm navigation.

140 We discovered that flagellum de- and repolarization in the model prokaryote

141 stablish a relationship between P. mirabilis flagellum density and cell motility in viscous environme

142 To test the relationship between flagellum density and velocity, we overexpressed FlhD(4)

143 lls of P. mirabilis and found that increased flagellum density produced an increase in cell velocity.

144 uring swarming--increases in cell length and flagellum density--and discovered that an increase in th

145 imorphic motile bacterium well known for its flagellum-dependent swarming motility over surfaces.

146 or its ability to move over agar surfaces by flagellum-dependent swarming motility.

147 heavy chains and of DLI1 at the base of the flagellum depends on the intermediate dynein chain DIC5

148 oxylipins derived from this activity inhibit flagellum-driven motility and upregulate type IV pilus-d

149 P. aeruginosa GcbA was found to regulate flagellum-driven motility by suppressing flagellar rever

150 regulation of initial surface attachment and flagellum-driven motility, GcbA and the phosphodiesteras

151 synthesis, including pili and holdfast, and flagellum ejection, is mediated in part by the scaffoldi

152 The bacterial flagellum exemplifies a system where even small deviatio

153 The Campylobacter jejuni flagellum exports both proteins that form the flagellar

154 portance of ECA for cell envelope integrity, flagellum expression, and resistance of enteric bacteria

155 into the structures occurs very early during flagellum extension.

156 tron microscopy showed that 2D6 IgA promoted flagellum-flagellum cross-linking, as well as flagellar

157 , like S. Typhimurium, requires a functional flagellum for epithelial cell invasion and macrophage up

158 ization and virulence factors to exploit the flagellum for their own secretion.

159 -B proteins and its sole expression prevents flagellum formation.

160 in flagella, SAS6L was absent during gamete flagellum formation.

161 ding relationships within the deeply derived flagellum-forming fungi (i.e., the chytrids).

162 The periodic beating of an isolated flagellum from Chlamydomonas reinhardtii exhibits probab

163 er the flagellar membrane, detachment of the flagellum from the cell body, and disruption of mitotic

164 important biophysical questions of sheathed-flagellum function.

165 rns et al. report that the Bacillus subtilis flagellum functions in surface-sensing.

166 vestigated the consequences of TviA-mediated flagellum gene regulation on flagellin-specific CD4 T ce

167 In many species, Ca(2+) bursts in the flagellum govern navigation to the egg.

168 As the flagellum grows longer, diffusion delays return of kines

169 life cycle forms of this parasite during new flagellum growth and cytokinesis.

170 llum lengthens outside the cell, the rate of flagellum growth does not change.

171 evidence for a simple physical mechanism for flagellum growth that harnesses the entropic force of th

172 nd unanticipated mechanism for constant rate flagellum growth.

173 The current known structure of the flagellum has not yet been fully correlated with the com

174 emonstrate that the rotation of the sheathed flagellum in both the mutualist Vibrio fischeri and the

175 ing of micro organisms with a single helical flagellum in circular channels.

176 As an application of GLLM, swimming of flagellum in fluid is simulated and propulsive force as

177 n rat and the centrosome of the spermatozoon flagellum in humans, suggesting a common mechanism of ac

178 ryoelectron tomography, the structure of the flagellum in three bending states.

179 his system has no homology to the eukaryotic flagellum, in which the filament alone, composed of a mi

180 In this study, we show how flagellum-independent migration is driven by the divisio

181 uction of curvature in one part of a passive flagellum induces a compensatory countercurvature elsewh

182 This disruption renders the proximal flagellum inflexible and alters the 3D flagellar envelop

183 d subsequent downstream events necessary for flagellum inheritance.

184 dividual sea urchin sperm with demembranated flagellum inside water-in-oil emulsion droplets and meas

185 s to adherence is unknown beyond ionic lipid-flagellum interactions in plant cell membranes.

186 mammalian host, Trypanosma cruzi discards it flagellum into the cytoplasm of the host cell.

187 The flagellum is a complex bacterial nanomachine that requir

188 The bacterial flagellum is a complex molecular machine that is assembl

189 The flagellum is a major virulence factor of motile pathogen

190 The bacterial flagellum is a motile organelle driven by a rotary motor

191 In Salmonella, the rod substructure of the flagellum is a periplasmic driveshaft that couples the t

192 The flagellum is a rotary motor that enables bacteria to swi

193 We explored how the C. jejuni flagellum is a versatile secretory organelle by examinin

194 rcuit to turn on biofilm formation, i.e. the flagellum is acting as a mechanosensor of surfaces.

195 The elastic flagellum is actuated by a preferred curvature model tha

196 The function of the L-ring in the mature flagellum is also thought to act as a bushing for the ro

197 The bacterial flagellum is an organelle that self-assembles outside th

198 The bacterial flagellum is assembled by a multicomponent transport app

199 The bacterial flagellum is assembled from over 20 structural component

200 the central transmembrane ring on which the flagellum is assembled.

201 erstanding the molecular architecture of the flagellum is crucial to elucidate the bending mechanism

202 secretion of proteins that assemble into the flagellum is driven by the proton motive force.

203 The assembly of the bacterial flagellum is exquisitely controlled.

204 mimetic nanobot driven by a rotating helical flagellum is often interpreted using the resistive force

205 The structure of the Gram-positive flagellum is poorly understood, and Bacillus subtilis en

206 Rotation of the bacterial flagellum is powered by a proton influx through the pept

207 more than an order of magnitude; the beating flagellum is simply unable to draw enough water through

208 The bacterial flagellum is the principal organelle of motility in bact

209 The sole cAMP source in the flagellum is the soluble adenylate cyclase (SACY).

210 ds, which are propelled by a single anterior flagellum, is characterized by a generalized helical mot

211 Here we analyse flagellum length, structure and molecular composition ch

212 As the flagellum lengthens outside the cell, the rate of flagel

213 a swimming motility screen to identify polar flagellum localization factors and discovered three gene

214 ly over the increasing length of the growing flagellum, maintaining a constant rate of subunit delive

215 xhibit spermiogenic arrest with acrosome and flagellum malformation.

216 a simultaneous estimation of multiple sperm flagellum material parameters, namely the cross-linking

217 ssociated with the lateral attachment of the flagellum) may be an adaptation associated with the bloo

218 ated behaviors, including biofilm formation, flagellum-mediated swarming motility, and type IV pilus-

219 We consider some ideas for how the flagellum might help attract water to the agar surface,

220 Flagellum monomers are pumped into the filament at the b

221 rotein, thereby establishing a checkpoint in flagellum morphogenesis.

222 proteins may co-ordinate both the pilus and flagellum motility systems.

223 The flagellum/motor thus participates in two functions criti

224 ariation in cell body helical parameters and flagellum number among H. pylori strains leading to dist

225 corporating variation of both cell shape and flagellum number predicts qualitative speed differences

226 Mutational perturbation of flagellum number revealed a 19% increase in speed with 4

227 19% increase in speed with 4 versus 3 median flagellum number.

228 , we identify CatSper Ca(2+) channels in the flagellum of A. punctulata sperm.

229 The flagellum of Campylobacter jejuni provides motility esse

230 gulated entry of a membrane protein into the flagellum of Chlamydomonas, we show that cells use an IF

231 per, and we identify the Slo3 protein in the flagellum of human sperm.

232 Although LmjAQP1 is localized to the flagellum of promastigotes, upon phosphorylation, it is

233 e transporter is selectively targeted to the flagellum of the kinetoplastid parasite Leishmania mexic

234 olutely dependent on the presence within the flagellum of the outer arm dynein alpha heavy chain/ligh

235 rolling the expression of genes required for flagellum or biofilm formation.

236 tional modules (e.g., biosynthesis of stalk, flagellum, or chemotaxis machinery) have consistent but

237 ng UV light and white light drives the robot flagellum periodically to swing to eventually push forwa

238 he hook protein connecting the cell body and flagellum play a role in locomotion.

239 the rotary motor that rotates each bacterial flagellum, powering the swimming and swarming of many mo

240 teraction within the pool at the base of the flagellum prevented entry of IFT-A into the flagellum an

241 uorescens SBW25 that was revealed only after flagellum production was eliminated by deletion of the m

242 mutants, defective in exopolysaccharides and flagellum production, respectively, did not protect mice

243 n SAS6, has been characterised recently as a flagellum protein in trypanosomatids, but associated wit

244 During assembly of the bacterial flagellum, protein subunits that form the exterior struc

245 mRNAs including those encoding acrosome and flagellum proteins.

246 In the reverse mode, when the flagellum pulls the cell, the precession is smaller and

247 In the forward mode, when the flagellum pushes the cell, the cell body is tilted with

248 avenumber and frequency propagating down the flagellum resulting in highly curved trajectories.

249 tecting antibodies against Salmonella LPS or flagellum, resulting in a high false-positive rate.

250 tes shows that defensin alpha-1 binds to the flagellum, resulting in flagellar membrane and axoneme a

251 rongly reclival, and antenna with homonomous flagellum, revealing new and important details in antenn

252 esults in the rapid pili-dependent arrest of flagellum rotation and concurrent stimulation of polar h

253 ts suggest B. subtilis senses restriction of flagellum rotation as the cell nears a surface.

254 we show that the interplay between pili and flagellum rotation stimulates the rapid transition betwe

255 is a process that often uses obstruction of flagellum rotation to trigger behaviors such as adhesion

256 tivity and degU transcription increased when flagellum rotation was prevented, and were dependent on

257 Using mutants of B. subtilis that prevent flagellum rotation, they measured the expression and act

258 d into a thin attachment pad associated with flagellum shortening.

259 lex cytoskeletal structure that connects the flagellum skeleton through two membranes to the cytoskel

260 icated basal bodies, which positions the new flagellum so that it can extend without impinging on the

261 le of FlgM is to inhibit FliA (sigma(28)), a flagellum-specific RNA polymerase responsible for flagel

262 Phenotyping revealed differences in flagellum structure, strain motility and immunogenicity,

263 oglycan (PG)-binding stator protein from the flagellum, suggesting it might serve a similar role in T

264 ) captured bacteria with a collar complex, a flagellum surrounded by a microvillar collar.

265 nvolved in citrate transport and metabolism, flagellum synthesis, and chemotaxis.

266 interaction of the phage with the bacterial flagellum takes place through a filament on the phage he

267 mpartment: TbAK1 is exclusively found in the flagellum, TbAK2 in the glycosome, and TbAK3 in the cyto

268 self-assembling nanomachines: the bacterial flagellum that enables cells to propel themselves throug

269 site is highly polarized, including a single flagellum that is nucleated at the posterior of the cell

270 Coluber constrictor) and coachwhips (Coluber flagellum) that indicated the probability of competitive

271 n linear quadrilateral nanodomains along the flagellum, the complex lacking CatSperzeta is disrupted

272 bility relative to the thrust exerted by the flagellum; this parameter and the geometric parameters o

273 Specific flagellum tip structures exist, yet their composition, d

274 subunits into and through the channel to the flagellum tip, and by isolating filaments growing on bac

275 by rounds of subunit crystallization at the flagellum tip, and polymer theory predicts that as the N

276 rse the hollow filament and exit the growing flagellum tip.

277 bility of both viable C. jejuni and purified flagellum to bind to Siglec-10, an immune-modulatory rec

278 through a narrow channel at the core of the flagellum to reach the assembly site at the tip of the n

279 a complex that assembles at the base of the flagellum to regulate protein composition and cilium fun

280 ncreases enhance the tendency for a tethered flagellum to start tugging on its binding.

281 cell shape is the lateral attachment of the flagellum to the cell body, mediated by the flagellum at

282 he flexibility of the hook that connects the flagellum to the cell body.

283 flagellum attachment zone, which adheres the flagellum to the cell surface, and for the rotation of t

284 lum attachment zone (FAZ), which adheres the flagellum to the cell surface.

285 tial organelles that position and adhere the flagellum to the cell surface.

286 g piece essential for linking the developing flagellum to the head during late spermiogenesis.

287 a narrow channel at the core of the growing flagellum to the tip, where they crystallize into the na

288 coat and interact with their receptor in the flagellum, triggering several physiological responses: c

289 n mode is triggered by an instability of the flagellum under reversal of the rotation and the applied

290 rs, but she also posited that the eukaryotic flagellum (undulipodium in her usage) and mitotic appara

291 The assembly of a flagellum uses a significant proportion of the biosynthe

292 The FP neck is tightly associated with the flagellum via a series of cytoskeletal structures that i

293 In the mutants, formation of the flagellum was inhibited at its earliest stage.

294 To measure cAMP dynamics in the sperm flagellum, we generated transgenic mice and reveal that

295 surface via a large bulge at the base of the flagellum, which is then remodeled into a thin attachmen

296 the stability of an inner-arm dynein in the flagellum, which may be shared by all the centrin-contai

297 t creates the pore through which the growing flagellum will elongate from the cell body.

298 nvolves symmetric waves propagating down the flagellum with a net linear propulsion of the sperm cell

299 This bacterium possesses a single flagellum with one rotor and two sets of stators, only o

300 ealed that KH1 is located at the base of the flagellum, within the flagellar pocket, where it associa