ライフサイエンスコーパス: flap

1 membrane-embedded 5-LOX-activating protein (FLAP).

2 ase (5-LO) aided by 5-LO-activating protein (FLAP).

3 venous network is used to revascularize the flap.

4 reverse the speciation observed in wild type FLAP.

5 HEK293 cells in the absence and presence of FLAP.

6 across rodent FLAP, as well as human and dog FLAP.

7 pletely inactive in assays with mouse or rat FLAP.

8 that generated for wild type human and mouse FLAP.

9 -binding fold fused to a three-stranded beta-flap.

10 ICL and, therefore, failed to release the 5' flap.

11 0001), reflecting the effect of the lamellar flap.

12 used to cover the macular hole with the ILM flap.

13 nce the changes in keratocyte density in the flap.

14 alloon fenestration of the aortic dissection flap.

15 nes were treated with a laterally positioned flap.

16 eflection of a full-thickness mucoperiosteal flap.

17 he macular hole was not covered with the ILM flap.

18 parating the strands of duplex DNA, creating flaps.

19 of clinical use of arterialized venous bone flaps.

20 is protein functions at DNA ends to generate flaps.

21 ctivate MutLalpha endonuclease to remove the flaps.

22 the removal of 1-nucleotide Okazaki fragment flaps.

23 al blades attached at the base of the dorsal flaps.

24 proteins recognize 1-nucleotide DNA and RNA flaps.

25 evious laser-assisted in situ keratomileusis flaps.

26 eaved, unthreaded, and partially threaded 5' flaps.

27 nt conformation occurred independently of 5'-flap accommodation and did not require active site metal

28 Comparison of rodent and human FLAP amino acid sequences together with an analysis of a

29 e therefore relatively immune to the shallow flapping amplitude.

30 econstruction with a vascularized myofascial flap and 2-year follow-up was in good health with no res

31 The hydrophobic interactions between flap and 80 s (80's) loop residues (mainly I50-I84' and

32 y treated with a modified coronally advanced flap and chorion membrane for root coverage.

33 y treated with a modified coronally advanced flap and Chorion membrane for root coverage.

34 ilizing the structural integrity between the flap and hinge regions.

35 s, flap endonuclease 1 (FEN1) removes the 5'-flap and maintains genomic stability.

36 from binding of Replication Protein A to the flap and sequestering it.

37 Host DNA repair restores the resulting 5'-Flap and single-stranded DNA (ssDNA) gap.

38 the boundary between the single-stranded 5' flap and the duplex, whereas FAN1 incised it three to fo

39 ere compared between methods of creating the flap and to the same variable before treatment using pai

40 d transient binding interactions between the flap and unprocessed DNA strand.

41 The focused question was, "Does flapped and flapless surgical technique influence CBL ar

42 dental implants placed in healed sites using flapped and flapless surgical techniques.

43 dental implants placed in healed sites using flapped and flapless techniques is comparable.

44 en energy harvester, which is different from flapping and vortex-induced-vibration (VIV).

45 uarthropod biramous limb, whereas the dorsal flaps and associated setal blades are homologous with th

46 the Ordovician exposes a second set of body flaps and reopens the question of how the two branches o

47 al bone loss"; "dental implant"; "surgery"; "flap"; and "flapless." Unpublished data, experimental st

48 ted with such animal models as walking, wing-flapping, and bird song.

49 further stabilize the closed conformation of flaps, and the hydrogen bonding interactions are mainly

50 luding the hinge and tip of the glycine-rich flaps, and the rest of the protein.

51 aft (CTG) when combined with a buccal single flap approach (SFA) in the regenerative treatment of int

52 odontal intraosseous defects with the single flap approach (SFA).

53 hropods indicate that anomalocaridid ventral flaps are homologous with lobopodous walking limbs and t

54 We find that the cleavage rates for 5 flaps are significantly higher than those for HJs for bo

55 When present, 5'-flaps are thought to thread under the helical cap, limit

56 n mechanism where junctions are bound and 5'-flaps are threaded (when present), and finally the subst

57 zes the essential removal of single-stranded flaps arising at DNA junctions during replication and re

58 The other series was active across rodent FLAP, as well as human and dog FLAP.

59 l wing kinematics; their long, slender wings flap at remarkably high frequencies for their size (>800

60 corneal inlay was implanted under a corneal flap at the center of the light-constricted pupil create

61 We hypothesize that the creation of a flap at the site of a leading strand discontinuity could

62 In arterialized venous flaps (AVFs) the venous network is used to revascularize

63 l primary procedure types (implant based and flap based) were eligible.

64 ting stress on interactions between the beta flap, beta' clamp, and sigma3.2.

65 ovided compounds that demonstrated excellent FLAP binding potency (IC50 < 10 nM) and potent inhibitio

66 ce of hospital variation for autologous free flap breast reconstruction is unknown.

67 The mean cost for autologous free flap breast reconstruction was $22677 (interquartile ran

68 influence cost variation for autologous free flap breast reconstruction.

69 on among patients undergoing autologous free flap breast reconstruction.

70 breast cancer and underwent autologous free flap breast reconstruction.

71 ries demonstrated strong inhibition of human FLAP but differential pharmacology across species and wa

72 PolB formed a ribonucleotide-containing flap by strand displacement synthesis that was cleaved b

73 uate the effectiveness of coronally advanced flap (CAF) + connective tissue graft (CTG) + PRF in Mill

74 MD) in conjunction with a coronally advanced flap (CAF) can serve as alternatives to autogenous donor

75 gival recession (GR) by a coronally advanced flap (CAF) combined with CM and/or EMD.

76 MD) in combination with a coronally advanced flap (CAF) on CDH, esthetics, and oral health-related qu

77 on defects treated with a coronally advanced flap (CAF) procedure.

78 for root coverage (RC) by coronally advanced flap (CAF) procedures in localized gingival recessions.

79 created: AVF (n = 6), conventional arterial flap (cAF, n = 6) and bone graft (BG, n = 6).

80 tissue grafts (CTGs) and coronally advanced flaps (CAFs) do not regenerate periodontal attachment ap

81 Factor C (yRFC) can load yPCNA onto 5'-ssDNA flaps, (CAG)13 triplet repeats, and homoduplex DNA.

82 ubsequently be applied to the defect and the flap can be repositioned and secured back in place.

83 The inhibitory effect of a long 5'-flap can be suppressed by its interaction with single-st

84 Immobilized DNA nanorobots with a switchable flap can then be actuated by a specific target DNA prese

85 Like the smart human sweating pores, the flaps can close automatically after the perspiration to

86 regulate sequential strand displacement and flap cleavage at other genomic sites.

87 ranslocation of Dna2 on ssDNA facilitates 5' flap cleavage near a single-strand-double strand junctio

88 Flap closure traps the Gag cleavage sites within the cat

89 f EMD alone may not be sufficient to prevent flap collapse or provide sufficient stability of the blo

90 was significantly (P <0.05) greater in open-flap compared with flapless surgery.

91 erences by impeding the LT-biosynthetic 5-LO/FLAP complex assembly.

92 human blood from females, and bioactive 5-LO/FLAP complexes were formed in female, but not male, huma

93 rativity of unfolding by trapping the closed flap conformation in a deep energy minimum.

94 -aminoquinazolin-4(3H)-ones bind to the open flap conformation of the enzyme and provided clues to ta

95 The striking reduction in flap conformational entropy is catalyzed, in part, by ar

96 rconversion between closed and open protease flap conformations facilitates the formation of a transi

97 ature of the procedure; a free microsurgical flap containing lymph nodes for the purpose of relieving

98 In particular, FEN1 removes flaps containing TNR sequences at a rate slower than mix

99 Of particular interest are flaps containing trinucleotide repeats (TNR), which have

100 cleaving a variety of branched, bulged, and flap-containing substrates.

101 atient was randomized by ocular dominance to flap creation with a femtosecond laser and the other eye

102 ith a femtosecond laser and the other eye to flap creation with a mechanical microkeratome.

103 ective tissue grafts with coronally advanced flaps (CTG + CAF) have been deemed the gold standard for

104 y selectively retracting one wing during the flapping cycle.

105 Control group (n= 10) received open flap debridement (OFD) and Demineralized Freeze Dried bo

106 is designed to evaluate the efficacy of open-flap debridement (OFD) combined with PRF, 1% MF gel, and

107 telet concentrates (PCs) in addition to open flap debridement (OFD) has been investigated.

108 d efficacy of PRF and 1.2% ATV gel with open flap debridement (OFD) in treatment of intrabony defects

109 treated either with autologous PRF with open flap debridement (OFD) or OFD alone.

110 is to evaluate and compare efficacy of open flap debridement (OFD) with or without PRF or PRF + 1.2%

111 s were treated with autologous PRF with open-flap debridement (OFD), PRF + HA with OFD, or OFD (contr

112 gous PRF and HA bone graft placed after open-flap debridement (OFD).

113 of intrabony defects in comparison with open flap debridement (OFD).

114 treated either with autologous PRF with open flap debridement (OFD+PRF) or OFD alone.

115 alized Freeze Dried bone Allograft with Open flap debridement and Demineralized Freeze Dried bone All

116 bone allograft and GTR and superior to open flap debridement procedures in improving clinical parame

117 ological outcomes of the combination of Open flap debridement, Amniotic membrane and Demineralized Fr

118 Keratocyte density in the flap decreased by 20% during the first year after LASIK

119 rrection, the creation of the lamellar LASIK flap decreased measured IOP by 0.94 mmHg.

120 generative/grafting procedures (10 RCTs); 2) flap design (three RCTs); 3) type of suturing (one RCT);

121 of surgical M3M removal techniques based on flap design, type of suturing, and periodontal care of M

122 surgery time were reduced markedly, as were flap dislocation and pterygium recurrence with Tisseel f

123 There were 2 cases of flap dislocation from the rhinostomy site 1 week post-op

124 eviates the inhibitory effect of RAD51 on 3'-flap DNA cleavage by MUS81-EME1 through its RAD51 filame

125 The method of creating a LASIK flap does not influence the changes in keratocyte densit

126 ery entailed sulcular incisions with minimal flap elevation and repositioning without advancement.

127 e that the exonuclease activity of mammalian flap endonuclease (FEN1) excises Pol alpha replication e

128 combined activities of polymerase B (PolB), flap endonuclease (Fen1), and DNA ligase are required to

129 replication proteins, including the enzymes flap endonuclease 1 (FEN-1) and DNA ligase I that comple

130 approach has been demonstrated that utilizes flap endonuclease 1 (FEN-1) fused to the Fok1 endonuclea

131 Human flap endonuclease 1 (FEN1) and related structure-specifi

132 This flap structure was cleaved by flap endonuclease 1 (Fen1) and the resultant nick was li

133 AMP-dRP group through its lyase activity and flap endonuclease 1 (FEN1) excises the 5'-AMP-dRP group

134 Flap endonuclease 1 (FEN1) is a structure-specific nucle

135 We identify that the flap endonuclease 1 (FEN1) is one of the interacting pro

136 DNA replication and repair enzyme Flap Endonuclease 1 (FEN1) is vital for genome integrity

137 Flap endonuclease 1 (FEN1) phosphorylation is proposed t

138 Flap endonuclease 1 (FEN1) plays a crucial role in both

139 nuclease 1 (FAN1), exonuclease 1 (EXO1), and flap endonuclease 1 (FEN1) process a substrate reminisce

140 nent in the maturation of Okazaki fragments, flap endonuclease 1 (FEN1) removes the 5'-flap and maint

141 Here, we demonstrate that flap endonuclease 1 (FEN1), a canonical lagging strand D

142 Polymorphisms and somatic mutations in Flap Endonuclease 1 (FEN1), an essential enzyme involved

143 Coordinating with flap endonuclease 1, the APE1 3'-5' exonuclease activity

144 rocessive 5'-3' exonuclease and secondary 5'-flap endonuclease activities participate in various DNA

145 Furthermore, although the flap endonuclease activity of FEN1 E359K was unaffected,

146 SAV6 is an FEN1 homologue that shows double-flap endonuclease and gap-dependent endonuclease activit

147 Next, DNA repair activities of DNA ligase, flap endonuclease and RNase H2 were monitored.

148 ol delta depended on RAD1, which encodes the flap endonuclease needed to cleave MMEJ intermediates be

149 haromyces cerevisiae, the MMR system and the flap endonuclease Rad27 act in overlapping pathways that

150 ase 1 (Exo1) is a 5'-->3' exonuclease and 5'-flap endonuclease that plays a critical role in multiple

151 Dna2, a flap endonuclease with 5'-3' helicase activity, is invol

152 Flap endonuclease-1 (FEN1) belongs to the Rad2 family of

153 Flap endonuclease-1 (FEN1) is a multifunctional, structu

154 Human flap endonuclease-1 (hFEN1) catalyzes the essential remo

155 EN1 is a member of the XPG/Rad2 family of 5'-flap endonucleases.

156 ogous with those in ancestral arthropod gill flaps/epipods, to migrate dorsally and fuse with the dor

157 The flaps failed in the DIEP group due to venous congestion.

158 ign, cement-/screw-retained restoration, and flapped/flapless surgical techniques.

159 at the forest floor level, and one utilizes flapping flight above the forest floor.

160 ntrast, Montagu's harriers predominantly use flapping flight during their migrations; this adult male

161 ternative, we used a vascularized myofascial flap for tracheal reconstruction.

162 pecific nuclease responsible for removing 5'-flaps formed during Okazaki fragment maturation and long

163 C4 Studies with small molecule inhibitors of FLAP have led to the discovery of a drug binding pocket

164 e presence of divalent metal ions, a free 5'-flap (if present), a Watson-Crick base pair at the termi

165 aled persistent traction on the retinal tear flap in 19 and 15 eyes, respectively.

166 Strikingly, coexpression of FLAP in A23187-activated HEK293 cells effectively restor

167 nd discovered that it is regulated by the 5'-flaps in the DNA strand to be displaced.

168 y co-opted to suppress growth of some dorsal flaps in the thorax and abdomen.

169 ess of fornix- and limbal-based conjunctival flaps in trabeculectomy surgery.

170 -double strand junction while attenuating 3' flap incision.

171 l was observed in both types of conjunctival flap incisions.

172 The flaps included a vertical rectus abdominis myocutaneous

173 However, this relief of flap-inhibition does not simply originate from binding o

174 Lower doses of the FLAP inhibitor MK886 were required to reduce LTB4 levels

175 asymmetric synthesis of a chiral quaternary FLAP inhibitor.

176 ll-carbon quaternary stereogenic center of a FLAP inhibitor.

177 FLAP inhibitors and the novel-type 5-LO inhibitors licof

178 ontaining 5-lipoxygenase-activating protein (FLAP) inhibitors are described.

179 of novel 5-lipoxygenase activating protein (FLAP) inhibitors focused on driving a reduction in lipop

180 es the annealed upstream 3'-flap of a double-flap intermediate resulting from 5'-incision of an abasi

181 ulated DNA ligase I to resolve a long double-flap intermediate, thereby promoting hairpin removal and

182 omere fragility by processing RNA:DNA hybrid/flap intermediates that arise from co-directional collis

183 ombination with EMD to avoid collapse of the flap into the bony defect during healing time.

184 ane covered by a modified coronally advanced flap is a new approach that has shown promising results

185 perfamily NAD(+)-binding domain, whereas the flap is strikingly similar to the ALDH superfamily dimer

186 ane covered by a modified coronally advanced flap, is a new approach that has shown promising results

187 e and its two multi-drug-resistant variants (Flap + (L10I/G48V/I54V/V82A) and Act (V82T/I84V)) as wel

188 (VA), IOP, number of sutures in the scleral flap, laser suture lysis, surgeon, and laterality of sur

189 inetically discriminates substrates based on flap length and flap sequence.

190 ining step of FEN1 switches as a function of flap length from product release to chemistry (or a step

191 However, for flaps longer than 30 nucleotides, FEN1 kinetically discr

192 There were no flap losses and all patients gained improvements in faci

193 gin (stage 1), an inward detached crescentic flap lying on the anterior lens (stage 2), a floating an

194 Y cork impacts membrane association and that FLAP may help shield an uncapped active site.

195 The concept of AVFs in osseous flaps may be feasible for revascularization of free flap

196 This study demonstrates that osseous free flaps may be supported and survive using the technique o

197 nteraction of Pol delta with PCNA eliminates flap-mediated inhibition of strand displacement synthesi

198 A flap, mimicking a D-loop or a hairpin structure, on the

199 For identical flapping motions, slow and fast modes coexist and corres

200 nds for binding to human G24A and mouse A24G FLAP mutant variants and compared the data to that gener

201 ling and root planing (SRP), modified Widman flap (MWF), and osseous surgery (OS) resulted in 23.2%,

202 vaginal (n = 49, 17%) or rectal advancement flap (n = 46; 16%), diverting stoma only (n = 27; 9%), p

203 ctions (ADRs), of which 2 cases demonstrated flap necrosis.

204 Conversely, the 3'-flap nuclease Rad1-Rad10 and enzymes known to disrupt re

205 Here we investigated how the 5' flap nucleases FANCD2-associated nuclease 1 (FAN1), exon

206 se activity cleaves the annealed upstream 3'-flap of a double-flap intermediate resulting from 5'-inc

207 onths, stretching by this pressure creates a flap of extra tissue that can be used to cover a defect

208 ydrogen bond interactions with Gly 48 in the flap of the enzyme.

209 rt that FEN1 processes substrates containing flaps of 30 nucleotides or fewer at comparable single-tu

210 ociated setal blades are homologous with the flaps of gilled lobopodians (for example, Kerygmachela k

211 that the conformational dynamics within the flaps of HIV-1 protease that form the lid over the catal

212 hydrogen bond interactions with the flexible flaps of the PR by incorporating gem-difluorines and alk

213 quences at a rate slower than mixed sequence flaps of the same length.

214 s), that produces heat through the constant "flapping" of wing-like pectoral fins and minimizes heat

215 ce, resulting in the unclamping and violent 'flapping' of the hanging-wall wedge.

216 N1 precisely cleaves single-stranded (ss) 5'-flaps one nucleotide into duplex (ds) DNA.

217 cs the pores in human skin, in which pre-cut flaps open to produce pores in Nafion sheets when humidi

218 otease and the substrate, resulting in rapid flap opening and substrate release, thereby allowing pro

219 Modulation of flap opening through protease-Gag interactions fine-tune

220 en cases required reconstruction with a free flap or graft.

221 -derived xenograft blocks without a surgical flap or membrane.

222 placement synthesis, the presence of long 5'-flaps or addition in trans of ssDNA suppress this activi

223 Coexpression of FLAP partially restored LTA4 hydrolysis product formatio

224 time, number of fenestrations of the intimal flap per patient, necessity of additional aortic stent-g

225 al mammary artery osteomyocutaneous chimeric flap (PIMOC) for salvage head and neck reconstruction.

226 5-Lipoxygenase activating protein (FLAP) plays a critical role in the metabolism of arachid

227 (CT)-based procedures and coronally advanced flap plus acellular dermal matrix grafts, enamel matrix

228 By use of SBDD, the flap pocket of Plm II has been discovered and constitute

229 electivity versus CatD, although varying the flap pocket substituent led to one Plm IV selective inhi

230 on of hydrophobic substituents occupying the flap pocket.

231 the enzyme and provided clues to target the flap pocket.

232 e repeats but also enhances formation of the flap precursor for expansion.

233 n acute wound healing after a full-thickness flap procedure in an incisional rat model.

234 Flap procedures performed in the West were the most expe

235 A model for the flap rate in cruising flight is applied to the Pileated

236 t just after taking off, the wing motion and flap rate of a large woodpecker may not be the same as i

237 Advances in microvascular free-flap reconstruction have extended the limits of resectio

238 utologous transverse rectus abdominis muscle flap reconstruction with an implant based reconstruction

239 Flap reconstructions performed at high-volume hospitals

240 te, as well as structural flexibility in the flap region.

241 lt bridge interactions between the hinge and flap regions are associated with changes in structure, m

242 rs are associated with peptide flips in the "flap" regions adjacent to the inhibitor binding site.

243 h flow techniques to examine the rates of 5'-flap removal on DNA substrates of varying length and seq

244 se mutants of MutLalpha are defective in the flap removal.

245 elucidate the nature of anomalocaridid trunk flaps, resolving their homology with arthropod trunk lim

246 ery involved 360 degree retinotomy, anterior flap retinectomy, and radial retinotomy for the manageme

247 f peripheral 360 degree retinotomy, anterior flap retinectomy, and radial retinotomy is to obtain ret

248 iminates substrates based on flap length and flap sequence.

249 sa and for CTGs virtually harvested by split-flap (SF) preparation minimum 1 mm deep or after deepith

250 rimentally removed, results in an ectopic T1 flap similar to prothoracic winglets present in fossil h

251 periodontal healing in terms of conventional flap sites.

252 unappreciated FEN1 function that enforces 5'-flap specificity and catalysis, preventing genomic insta

253 Gen, like HsGEN1, efficiently cleaves HJs, 5 flaps, splayed arms, and replication fork structures.

254 ctivates MUS81-EME1 for replication fork and flap structure cleavage by relaxing substrate specificit

255 This flap structure was cleaved by flap endonuclease 1 (Fen1)

256 compounds generate a substantially different flap structure, in which a key tryptophan residue is dis

257 the downstream Okazaki fragment to create a flap structure.

258 ive site processes both recessed ends and 5'-flap substrates.

259 Regarding the secondary outcomes, in the flap surgery group, the WMD of CAL gain was 1.34 mm, and

260 Periodontal flap surgery is frequently used to remove subgingival de

261 rich fibrin (PRF) combined with conventional flap surgery on growth factor levels in gingival crevicu

262 Flap surgery was performed with EDTA conditioning of the

263 s in less MBL compared with traditional open-flap surgery.

264 c review of articles relevant to periodontal flap surgical procedures in smokers was conducted from 1

265 smokers could be candidates for periodontal flap surgical procedures.

266 g on clinical outcomes following periodontal flap surgical procedures.

267 In this study we aim to assess the flap survival of osseous AVFs in a pig model.

268 odified preserved nasal and lacrimal mucosal flap technique in EES-DCR for treating PANDO is simple a

269 odified preserved nasal and lacrimal mucosal flap technique in EES-DCR was applied in all 27 eyes of

270 odified preserved nasal and lacrimal mucosal flap technique in endonasal endoscopic dacryocystorhinos

271 The inverted ILM flap technique was adopted, except that no extra surgica

272 to beyond 1 year following the inverted ILM flap technique, especially if the macular hole was not c

273 rongly reflexed cupule stalk and two lateral flaps that partially enclose an erect seed.

274 e flight system because smaller insects must flap their wings at higher frequencies to generate suffi

275 More accurate flap thickness is achieved with Visumax femtolasik.

276 an) was used for preoperative pachymetry and flap thickness measurement.

277 ety, predictability, ocular aberrations, and flap thickness predictability of Visumax femtosecond las

278 In group I, the mean postoperative actual flap thickness was 100.12 +/- 16.1 mum (81 to 122 mum),

279 sidues energetically steer an inverted ss 5'-flap through a gateway over FEN1's active site and shift

280 nds recessed ends at its base and threads 5' flaps through a narrow aperture within its interior.

281 repositioning of the conjunctival autograft (flap time) was significantly shorter in the fibrin glue

282 to migrate dorsally and fuse with the dorsal flap tissue thereby bringing new functional gene network

283 T2/T3 wings suggest that the transition from flaps to wings required ventrally originating cells, hom

284 The number of surgical debridements, flap use, or duration of antibiotic therapy was not asso

285 ement during lunge feeding: the flippers are flapped using a complex, hydrodynamically active stroke

286 latory or inhibitory effects of WH on FEN1's flap versus gap endonuclease activities are consistent w

287 f the surface of the transplanted myofascial flap was analyzed in the airway environment.

288 Thirty eyes in group (I) in which the flap was created with Visumax FSL, while in group II (30

289 N1 selects for but does not incise the ss 5'-flap was enigmatic.

290 ation and persistent traction on the retinal flap was evaluated with B-scan ultrasonography and OCT.

291 n four patients, fenestration of the intimal flap was performed twice.

292 The flap was then utilized in a series of patients with vess

293 Medial femoral condyle flaps were elevated in 18 pigs.

294 Full-thickness flaps were raised, and, after suturing, EMD was injected

295 notypes: extensive necrosis of ischemic skin flaps, which was reversed by adenoviral expression of AN

296 ugh experiments and simulations of arrays of flapping wings that propel within a collective wake, we

297 cession were treated by a coronally advanced flap with CT graft resulting from the de-epithelializati

298 ay be feasible for revascularization of free flaps with an inadequate artery but well developed veins

299 under the helical cap, limiting reaction to flaps with free 5'-terminiin vivo Here we monitored DNA

300 ve techniques using free vascularised tissue flaps with penile implants are undesirable in this often

301 bears a separate dorsal and ventral pair of flaps, with a series of setal blades attached at the bas