ライフサイエンスコーパス: flaw

1 were excluded from review for an identified flaw.

2 tical phylogenetic tests plagued by profound flaws.

3 We propose changes to address these flaws.

4 and often demonstrate extreme sensitivity to flaws.

5 ethod comparison due to a number of inherent flaws.

6 ves all of these studies have methodological flaws.

7 fety seat legislation and had methodological flaws.

8 esults are inflated by recall bias and other flaws.

9 ffered evidence for this hypothesis has many flaws.

10 l interactions or the result of experimental flaws.

11 terventions evaluated were the most frequent flaws.

12 e coming from trials with significant design flaws.

13 selecting similar regions may have potential flaws.

14 l hernia and to evaluate their strengths and flaws.

15 or HLA Abs, is theoretically devoid of these flaws.

16 d with reviewer ability to report manuscript flaws.

17 patients is further limited by methodologic flaws.

18 e sample-size scaling of the distribution of flaws.

19 ue to reliance on a single primer with known flaws.

20 es are limited by significant methodological flaws.

21 ause of their brittleness and sensitivity to flaws.

22 nd management of chest pain (CP) has several flaws.

23 sensitivity with respect to cracks and other flaws.

24 completeness, or simply because of avoidable flaws.

25 whereas SHIP1 inhibition worsened migratory flaws.

26 but the study was limited by methodological flaws.

27 size fits all" paradigm for drug delivery is flawed.

28 f agents to use in adjuvant trials is deeply flawed.

29 dwich configuration of the benzene dimer are flawed.

30 to assess whether the original analyses were flawed.

31 studies have been small and methodologically flawed.

32 pt, relating to the shape of sample SADs, is flawed.

33 irective concept itself may be fundamentally flawed.

34 logy of fluctuating asymmetry studies may be flawed.

35 al level analysis or director opinion may be flawed.

36 dology used to develop these models is often flawed.

37 past GeneChip analyses may be significantly flawed.

38 t or (2) measurements of sugar transport are flawed.

39 the internal initiation hypothesis is often flawed.

40 For some GLs, the "Scientific rigor" domain flawed.

41 ich the data analysis and interpretation are flawed.

42 that data from these studies are potentially flawed.

43 ignore variability within the genome may be flawed.

44 e argue that the courts' reasoning is deeply flawed.

45 that mechanisms for tolerance to insulin are flawed.

46 hypothetical deployment scenarios) would be flawed.

47 rticles, we show that this assumption may be flawed.

48 an, however, that the current procedures are flawed.

49 ers cited to point out their merits or their flaws?

50 he 'epidemiological studies are sufficiently flawed'; (2) 'the biological evidence is of moderate str

51 nferred by statistically and chronologically flawed age-depth interpolations, and in several the ages

52 rmality in behavioral force-matching and the flawed agency judgments characteristic of positive sympt

53 agome geometry that contained pre-fabricated flaws always failed at the same load as the pristine spe

54 sed conferences and risk assessment studies, flawed analyses (including a recent tome from the OECD),

55 ys in which mental health systems may become flawed and compare philosophical arguments that deal wit

56 o being, how it is calculated, and how it is flawed and contributing to decreasing physician payments

57 In later coverage it became a flawed and damaging product.

58 d in academic settings, and methodologically flawed and did not measure clinically meaningful outcome

59 was that the SP evidence base was seriously flawed and did not warrant the introduction of SP.

60 ultiplicative rating scale of the MacDQoL is flawed and does not provide scientific measurement of VR

61 off-the-shelf technologies are fundamentally flawed and inaccurate for the operating conditions descr

62 reliance on metrics that are mathematically flawed and insufficiently diverse to account for the var

63 suggest that this estimate is statistically flawed and misleading and says nothing about the impacts

64 g of such processes are established based on flawed and non-representative models.

65 n that show an effect on cardiac disease are flawed and offer no insight into normal human physiology

66 data matrices indicate that this approach is flawed and should be avoided, and that within the marine

67 Methods of lethal injection anaesthesia are flawed and some inmates might experience awareness and s

68 y grizzly bears post-wolf reintroduction are flawed and tenuous at best.

69 hemical investigations have been technically flawed and that NAA may not be associated with brain ene

70 ysis of Australopithecus sediba mandibles is flawed and that specimen LD 350-1 cannot be distinguishe

71 ts have been discredited, the methodology is flawed and the causal inference drawn from the results p

72 ve led to the claim that this explanation is flawed and therefore that Fisher's hypothesis can and sh

73 Their conclusions are based on flawed and untested assumptions.

74 in septic patients, the experimental design flaws and biases of recent low-dose (physiologic) steroi

75 ganisms should be relatively free of initial flaws and defects.

76 and interpretation are sometimes subject to flaws and errors.

77 donation, the Iranian Model now has serious flaws and is potentially inhibiting substantial growth i

78 linical development, including due to design flaws and reporting bias.

79 g by shear-band sliding in the presence of a flaw, and thus exhibit toughness-strength relationships

80 ecause the methods of most studies have been flawed, and AVMs tend to be treated once they are discov

81 s as merely non-specific rigid inclusions is flawed, and each protein has a unique mechanical signatu

82 valuating CAM therapies are methodologically flawed, and often times there are inconsistencies across

83 266-269, ) suggests that these studies are flawed, and posits that such methodologies cannot be use

84 ssume a definitive prognosis--are clinically flawed, and procedural barriers may further limit their

85 se if the methods used to conduct the SR are flawed, and reporting of the SR is incomplete.

86 ocks at the onset of Cenozoic orogenesis are flawed, and that some metamorphism of Greater Himalayan

87 gest that older detection methodologies were flawed, and the limitations of these methods could accou

88 onstrating the validity of this assertion is flawed, and the residual intrinsic variability so define

89 We address their inconsistencies and flaws, and present scientific facts and our perspectives

90 show that this "contradiction" is based on a flawed approach to calculating the wavelength in models.

91 hat sexual selection theory is fundamentally flawed are simply wrong and ignore an enormous body of e

92 No flaws are observed within the frustule material down to

93 Lower barriers to publication of flawed articles are seen in the increase in number and p

94 articles or an increase in the rate at which flawed articles are withdrawn.

95 Retraction of flawed articles is an important mechanism for correction

96 this reflects an increase in publication of flawed articles or an increase in the rate at which flaw

97 initial cell cluster size, and are therefore flawed as universal measures of plasmid transfer efficie

98 ighly rated reviewers reported twice as many flaws as poorly rated reviewers.

99 Essential assumptions about this process are flawed, as shown by results with the preclinical, nonhum

100 ion is based on the artefactual results of a flawed assay; in addition, the authors misinterpret a ke

101 We show here that this is a flawed assumption because regional climates have changed

102 ed brainstem structures in birds is based on flawed assumptions of homology to mammals.

103 standing of the importance that pre-existing flaws at the intaglio surface have on fatigue failures.

104 and other environmental factors, providing a flawed basis for beach closure decisions.

105 0 and 1,000 million years ago is shown to be flawed because it extrapolates from slow-evolving verteb

106 The epidemiological studies were considered flawed because it was not possible to distinguish reliab

107 monitoring resistant mutants are potentially flawed because no tissue culture system adequately refle

108 e (mocap) technology and the spectrograph is flawed because only vocal articulators are hidden.

109 However, many existing approaches are flawed because the assumptions of what cause excessive l

110 However, this approach is flawed because the density of T-tubules as well as non-T

111 archetypal natural kind-may be fundamentally flawed because the very concept of "the gene" as a discr

112 obal biogeochemical cycling, are potentially flawed because they do not consider this land use in the

113 ent biological classifications are seriously flawed because they fail to (i) standardize criteria for

114 alternative cover stories are fundamentally flawed because they introduce new forms of demand.

115 f effect cannot be attributed to a technical flaw, because identical doses of zVAD were able to rescu

116 ual progression of "isolating mechanisms" is flawed, because intra-group random mating is assumed.

117 Pak2 leads to early embryo lethality due to flawed blood vessel formation in the embryo body and yol

118 rchers as attested to by the substantial, if flawed body of literature on the topic.

119 Both are flawed by distorting the structure of the symmetric junc

120 the ITT analysis for all lesions, which was flawed by major protocol deviations in 8.5% of the patie

121 t, compared to a 3D observation, 2D data are flawed by over-reporting and under-reporting of locomoto

122 in the lateral geniculate nucleus have been flawed by potential sampling biases favoring larger syna

123 Both of these studies, however, were flawed by the lack of suitable controls for assessing vi

124 Preclinical studies have been flawed by use of models of transient not permanent brain

125 f proteins and detect backbone or side-chain flaws by taking into account an ensemble average of chem

126 ing US biomedical research from its systemic flaws" by Alberts and colleagues in the Proceedings of t

127 These methodologic flaws can lead to false claims, inconsistencies, and har

128 rge sequences and corrects a number of minor flaws causing misreporting of hits in exceptional cases.

129 r of the NQMI have been invalidated by major flaws, chief among them the comparison of undifferentiat

130 en due to inadequate preclinical testing and flawed clinical development programs.

131 nd the dual-reporter method may thus produce flawed conclusions about the properties of the system, p

132 ntervention and control groups, major design flaws, contradiction by subsequent larger higher quality

133 Instead of the usual, conceptually flawed control, we used a series of novel transfer tasks

134 previous studies, in which methodologically flawed cue-target tasks were used.

135 To avoid training on possibly flawed data, the development of polyadq began with a de

136 can stable multitasking emerge despite this flawed decision-making?

137 species, by taking into account the initial flaws (defects) in newly formed systems.

138 e horizons), and definition of outcomes (eg, flawed definition and grouping together of adverse effec

139 ogram's difficulties stemmed directly from a flawed design that spread funds previously earmarked for

140 Estimates of material surface flaw distributions and fatigue parameters for 3 reinforc

141 icates that methods associated with PISO are flawed due to non-synchronization of lattice temperature

142 us errors (e.g. failure to identify and stop flawed efforts, rejection of effective vaccine strategie

143 Unfortunately, many of these studies are flawed, either through questionable experimental design

144 insensitivity of failure to the presence of flaws even when made entirely of intrinsically brittle m

145 ence-based knowledge suggest that systematic flaws exist in the production of scientific evidence, in

146 nularity and coding inaccuracies may lead to flawed findings.

147 s low as reasonably achievable), are fatally flawed, focusing only on molecular damage while ignoring

148 ation, but these data are disproportionately flawed for AIAN because of racial misclassification.

149 ties that provide a crack-arrest barrier for flaws formed in the brittle enamel1.

150 lysis are increasingly cited as conceptually flawed, given the extreme variation within traditionally

151 ion in a way that is not dependent on either flawed gold standards or the input data itself.

152 While methodologic flaws hamper drawing strong conclusions from this litera

153 Methodological flaws have been indicated as a possible explanation for

154 rs intrinsically inefficient, and scientific flaws have been noted by many authors.

155 epair is not unique to MRL-Fas(lpr) mice, as flawed healing is a feature of other lupus-susceptible m

156 included in this review have methodological flaws however.

157 These studies are flawed if the DNA is isolated from misidentified modern

158 science, research experiences may reinforce flawed images especially of research practices and conce

159 A critical flaw in Branigan & Pickering's (B&P's) advocacy of struc

160 n perception and judgment is therefore not a flaw in investigating top-down effects of cognition on p

161 which has long been considered as a critical flaw in lithium-sulfur batteries.

162 We address a conceptual flaw in the backward-time approach to population genetic

163 We have analyzed a systematic flaw in the current system of gene identification: the o

164 y tri-n-butylstannane (SnH) reveal a serious flaw in the current view of the kinetic radical chain: t

165 Finally, we report a flaw in the Egfr-null mosaic Minute+ clone approach.

166 Due to a flaw in the International Classification of Diseases, Ni

167 ive temperature, suggesting that there was a flaw in their assembly.

168 Our data suggest that PLE patients have a flaw in their immunoregulatory response to ultraviolet-r

169 ard et al. (2014) identifies an experimental flaw in these previous studies suggesting that astrocyte

170 The flaw in this approach is that distributions of species a

171 A critical flaw in this picture has long been that the reported lip

172 oblems in other strains of mice suggesting a flaw in this theory.

173 ngiogenesis in skeletal muscle is profoundly flawed in both structure and function, with no evidence

174 These studies, although often flawed in design and generally of inadequate statistical

175 ith all experimental animal models, they are flawed in one way or another by virtue of the means by w

176 e, which have been shown to be significantly flawed in recent investigations.

177 ival from earlier initiation of dialysis are flawed in that they have measured survival from start of

178 vement in understanding (all P<.05) but were flawed in that they may have mistaken rote memorization

179 not been effective, but the study design was flawed in that trial.

180 ations of social psychology as fundamentally flawed in understanding stereotype accuracy and the effe

181 quality or the reviewer's ability to detect flaws in a fictitious manuscript.

182 onsistent evidence of serious methodological flaws in a significant number of economic evaluations.

183 ies, ranging from disease-specific intrinsic flaws in blood supply, angiogenesis, and matrix turnover

184 d with St John's wort, most have significant flaws in design and do not enable meaningful interpretat

185 The review revealed major methodologic flaws in design, reporting and results of the studies, i

186 to frequent reliance on claims data with its flaws in determining quality, fragmentation of measureme

187 ome of the discrepancies can be explained by flaws in experimental design and methodology.

188 ly determined but recent data indicates that flaws in innate immune responses, involving the interfer

189 by piezoelectric crystals was used to detect flaws in metals.

190 ion are discussed, which highlight the major flaws in parametrization of existing models.

191 Commonly identified flaws in RCTs were as follows: insufficient data provide

192 od either reaches atomic accuracy or exposes flaws in Rosetta's all-atom energy function, indicating

193 on system, and points to potentially serious flaws in simplified mathematical relationships often use

194 In addition, we use these results to expose flaws in some of Michael Behe's arguments concerning mat

195 s, but some of those studies were plagued by flaws in study design or analysis.

196 In research, lack of coordinated effort, flaws in study design, changes in simulator-validation c

197 from consideration unless there were serious flaws in study design.

198 There are 2 inherent flaws in such an approach.

199 strategy for identifying unpredicted design flaws in synthetic genomes and for elucidating rules gov

200 These two findings highlight the serious flaws in the assumptions of the conventional mobile-immo

201 We discuss fundamental flaws in the CP, including the lack of consistency of vi

202 However, we find serious flaws in the data, methods, and interpretations of this

203 Many flaws in the design and interpretation of new experiment

204 rd work is required to prepare reagents, but flaws in the design of many binding experiments limit th

205 mplex interventions in health care research, flaws in the development process immediately impact the

206 ttributing the differences to methodological flaws in the earlier article.

207 l composition, can be directly attributed to flaws in the force field's ability to properly account f

208 This process, which can lead to undesirable flaws in the form of bubbles, blemishes or voids, limits

209 ifferent statistical methods, or fundamental flaws in the hypothesized association between hospital-w

210 Here, I argue that emerging flaws in the integrity of the peer review system are lar

211 ions of genomic sequences reveal fundamental flaws in the Linnaean paradigm that necessitate a new vi

212 Despite some methodologic flaws in the literature, psychological interventions may

213 so many HIV patients has led to fundamental flaws in the management of advanced HIV infection.

214 ese guidelines are based reveals significant flaws in the methodology and conduct of the relevant met

215 Although flaws in the methodology have been acknowledged, one gro

216 We identified substantial flaws in the original and updated GFT models at all thre

217 After revealing flaws in the psychological approach, we introduce a psyc

218 This paper will outline some of the flaws in the studies thus far, and problems for the futu

219 rch-can go a long way to remedying remaining flaws in the system.

220 t al.'s central argument, there are numerous flaws in the way people use causal models.

221 some important conceptual and methodological flaws in their argument, we report the results of a seri

222 y is a new, unifying synthesis that draws on flaws in three leading theories of ageing.

223 ental sequence of human language learning is flawed: in fact, infants already know the meanings of se

224 ryos and fetuses) to pervasive architectural flaws (including pseudogenes, parasitic mobile elements,

225 Methodological flaws, including survival bias, and heterogeneity betwee

226 However, this flaw is less relevant as a source of bias in direct comp

227 This flaw is termed lead-time bias.

228 hese have well understood caveats; a notable flaw is the ad-hoc treatment of multi-loops, also called

229 ing notion of local similarity has a serious flaw: it does not discard poorly conserved intermediate

230 Concern over the impact of flawed measurement continues to nag epidemiology.

231 Many previous analyses have used flawed metrics to evaluate herbicide intensity and toxic

232 The test, however, is based on a flawed model of causality, and the ecological groups are

233 o produce a valid topology from an otherwise flawed model.

234 f possible bi-site mechanisms reveal serious flaws, not previously recognized.

235 uctural valve deterioration (SVD) is a major flaw of bioprostheses.

236 Burnt tuna (BT), or yake-niku, is a quality flaw of the muscle characterised by a pale colour and gr

237 Strategies to ameliorate the flaws of current chemotherapeutic agents, while maintain

238 the field can be attributed to the inherent flaws of layer-by-layer printing and, in particular, ani

239 Emerging evidence suggests that design flaws of randomized controlled trials can result in over

240 data in delineating truths and illuminating flaws of retrospective data on a controversial topic.

241 ime of colonoscopy may aid in overcoming the flaws of surveillance.

242 We first describe the flaws of the traditional (chi-squared) tests for both al

243 echnological considerations and the inherent flaws of these methods, which may have an impact on the

244 he glomeruli, it represents a feature, not a flaw, of the olfactory bulb.

245 takes into consideration prevalent security flaws on these routers.

246 Finally, defects and flaws on TiO2 film were easily recognized via surface pr

247 chemical shifts for approximately 94% of the flaws, on average, without introducing a significantly l

248 We reject those notions as either logically flawed or at best insufficient in the absence of natural

249 when the available transcript annotation is flawed or incomplete.

250 Their analysis is fundamentally flawed, owing to the use of model ensembles with too few

251 Our findings challenge the existing flawed paradigm of maximum dose treatment, a strategy th

252 is by another Y-family DNA polymerase and/or flawed participation of an accessory protein is a more l

253 ing respiratory mucosal sampling methods are flawed, particularly in a pediatric bronchiolitis settin

254 umerous phase II studies and underpowered or flawed phase III studies.

255 This flawed process results in billions of dollars worth of v

256 nd continues to be misinterpreted, producing flawed projections and misdirected health goals.

257 This aberrant UVB response represents flawed protection from UVB damage potentially resulting

258 vement created and perpetuates the seriously flawed protocol of lethal injection.

259 uilibrium for PAHs and SOA are fundamentally flawed, providing an explanation for the persistent disc

260 be necessary to avoid false conclusions from flawed Q-PCR assays for which sequence variation among i

261 40 years that these inferences are based on flawed reasoning and obscured by model mimicry.

262 owever, normative databases can sometimes be flawed relative to atypical ONH or RNFL morphologies and

263 t or a 2-way ANOVA, in these situations give flawed results and should not be used.

264 ntially drive false associations and lead to flawed results.

265 hough perhaps well-intentioned, was based on flawed scientific interpretation of trial results that c

266 ), fails to form in this agglomerate causing flawed segmentation.

267 the accompanying plasticity helps to reduce flaw sensitivity in the glass, thereby promoting structu

268 dy to CA19.9 (a highly visible but partially flawed serum biomarker for several cancers) was radiolab

269 sory superiority depends on methodologically flawed studies and biased clinical evaluations.

270 Meta-analyses based on flawed studies or studies that lack demonstrated assay s

271 laparoscopy is mostly from the research with flawed study designs.

272 tation of this phenomenon in the article was flawed, subsequent simulations show that the effect comp

273 produce multiple missing values (MVs) due to flaws such as dust, scratches, insufficient resolution o

274 by which the 'barrier function' might become flawed, such as mossy fiber sprouting, are discussed.

275 city' are poorly defined terms that serve as flawed surrogates for multiple environmental and genetic

276 blems, such as lack of access, inequity, and flawed system designs.

277 Since flawed systems undermine fidelity, threatening the patie

278 of fidelity to the patient is compromised in flawed systems, thus threatening professional integrity.

279 pothesis that RCTs have fewer methodological flaws than non-RCTs, limitations of 17,591 RCTs and 39,0

280 only used amino acid encoding method has the flaw that leads to large computational cost and recognit

281 In this article, we describe flaws that affected that study's conclusions and present

282 However, several key methodological flaws that are hindering progress in the study of insect

283 Critical examination of the evidence reveals flaws that leave room for alternative interpretations, s

284 Many of these studies have methodological flaws that preclude an accurate estimate of the long-ter

285 Although not without flaws, the model provides an explanation for why primary

286 r was modestly correlated with the number of flaws they reported (R=0.53).

287 We also show that, while flawed, this data set is still a useful tool for method

288 ent in toughness and strength with very high flaw tolerance of zirconia/Ta composites.

289 toughening strategy in nacre's hierarchical flaw-tolerance design.

290 , has already been used to shed light on our flawed understanding of natural levels of Pb in Earth's

291 rs <Sn> to average methylenic travel <Dn> is flawed when compared to molecular dynamics simulations o

292 n, we show how community state-clustering is flawed when it comes to characterizing within-host dynam

293 Conventional systems are potentially flawed when PY is used as the control signal because the

294 But, this technique becomes fundamentally flawed when there are unaccounted sources of variability

295 ically that it can introduce a more sinister flaw: when there is complete linkage between loci affect

296 edian cracks in samples with no pre-existing flaws, while indenters with larger indenter angles canno

297 A critical flaw with detergent approaches is the removal of the pro

298 s that records/recalls are likely to be also flawed with systematic person-specific biases, so that f

299 al research has an identified methodological flaw, with RCTs having as many limitations as non-RCTs.

300 and a decrease in the time-to-retraction of flawed work.