ライフサイエンスコーパス: flexibility

1 t form of iC3b that features high structural flexibility.

2 at captured reward sensitivity and cognitive flexibility.

3 ntingencies change is critical to behavioral flexibility.

4 for BG1 recognition of V1V2 involving glycan flexibility.

5 iors, including working memory and cognitive flexibility.

6 we opt for model-based learning and adaptive flexibility.

7 sponse strategy at the service of behavioral flexibility.

8 , compared to its limited role in perceptual flexibility.

9 ct to analytical performance and operational flexibility.

10 with large heart-shaped cages and framework flexibility.

11 onding Ala266 of AP-1 Jun protein lacks such flexibility.

12 obility, optical transparency and mechanical flexibility.

13 nd searching and allows for data downloading flexibility.

14 l interconnectivity, high-device density, or flexibility.

15 een model hydrophobic materials with tunable flexibility.

16 als' selectivity can actually be improved by flexibility.

17 evels are a primary determinant of metabolic flexibility.

18 complex exhibits considerable conformational flexibility.

19 late with differences in backbone structural flexibility.

20 er) to uncover their catabolic diversity and flexibility.

21 variability (HRV), a marker of physiological flexibility.

22 pecialized to specific tasks while retaining flexibility.

23 adsorption and selectivity as a function of flexibility.

24 during a reversal task requiring behavioral flexibility.

25 , while Ca(2+) uptake reduces conformational flexibility.

26 at are stable and maintaining conformational flexibility.

27 the two linkers together and reducing their flexibility.

28 uning of emotional responding and behavioral flexibility.

29 by both solvent accessibility and structural flexibility.

30 charge-discharge measurements with excellent flexibility ( 100% retention in charge storage capacity

31 mediated pattern separation leads to "memory flexibility"-a selective improvement in the ability to o

32 roaches to studying the concept of metabolic flexibility across a range of activity and inactivity.

33 This genomic flexibility after only one passage indicates that influe

34 Its flexibility allows a suitable visualization for both sma

35 This circuit flexibility allows animals to modify their behavioral re

36 vide strong evidence that the conformational flexibility also plays an important role in regulating p

37 However, the key determinants of metabolic flexibility among relevant clinical populations remain u

38 h chemistry including fascinating structural flexibility and a wide range of compositions and physica

39 ion of temperature-dependent polyester chain flexibility and accessibility of the enzyme active site.

40 Mechanical flexibility and advanced light management have gained gr

41 y switch is entirely dependent on the unique flexibility and binding properties of these intrinsicall

42 ng of an as-yet unknown relationship between flexibility and brain state.

43 alphaI and betaI is attributed to the alphaI flexibility and could accommodate the alphaLbeta2-mediat

44 se systems are costly and often restrict the flexibility and customization of experimental protocols.

45 earable applications which require excellent flexibility and durability.

46 e population to code stimulus intensity with flexibility and efficiency.

47 corroborate proposed mechanisms of spectrin flexibility and elasticity.

48 w, 4 kcal/mol to 5 kcal/mol, consistent with flexibility and facile reversible unfolding.

49 ioesterase (TE) domain has limited substrate flexibility and functions as a gatekeeper in the process

50 Metabolic flexibility and glucose flux were examined in ZDF rats d

51 ular photodetector with excellent mechanical flexibility and high sensitivity demonstrates the applic

52 /analysis tools (e.g., normal mode analysis, flexibility and hotspot analysis, cryo-EM flexible fitti

53 at feeding impairs skeletal muscle metabolic flexibility and induces insulin resistance, whereas exer

54 propriately for a specific function, implies flexibility and is usually thought to be incompatible wi

55 tructural analysis because of their inherent flexibility and lack of predictable structure.

56 morphous InGaZnO (a-IGZO) possess mechanical flexibility and outstanding electrical properties, and h

57 We demonstrate the flexibility and power of C-DSLM by quantifying fluoresce

58 We show that mutation to serine permits loop flexibility and recovers MAb PL-2 binding.

59 y behaviours as therapy to improve metabolic flexibility and reduce weight gain risk.

60 promotes the synergistic balance between the flexibility and rigidity, and the unique molecular recog

61 , which support memory, attention, cognitive flexibility and sensory responses.

62 rization interface (helix H6) as well as the flexibility and solvent exposure of helix H11.

63 s that accounted for both the conformational flexibility and the energetic factor of binding, we succ

64 Together with their conformational flexibility and the transient nature of their interactio

65 Examining flexibility and variation in caregiver socialization and

66 existing genomic modification tools, adding flexibility and versatility to vector genome targeting.

67 er substrate that shows excellent mechanical flexibility and visible transparency while maintaining n

68 We propose that the software's reliability, flexibility, and ability to identify novel lipid molecul

69 re DLPFC/TPJ activity recruited during moral flexibility, and examined its effect on other domains of

70 h as no-washing steps, rapid detection, high flexibility, and high sensitivity.

71 cnR orders its N terminus, decreases helix 1 flexibility, and induces conformational changes that res

72 nctions, including working memory, cognitive flexibility, and inhibition, are impaired in schizophren

73 ay reliable conductivity, enhanced porosity, flexibility, and stability to washing.

74 erotonin neurons support a role in cognitive flexibility, and suggest a revised model of dopamine-ser

75 y; however, the factors that control lineage flexibility are mostly unknown.

76 however, the neural circuits underlying such flexibility are unclear.

77 nd highlights the need for legal clarity and flexibility as donation and transplantation systems cont

78 ty increased with increasing polyester-chain flexibility as evidenced from differences in the hydroly

79 ses upon UVPD, signaling an increase in loop flexibility as the metal cation disrupts the loop intera

80 ontextual control over LHb-mediated response flexibility as vertebrate brains became more complex.

81 nd growth), while allowing a large degree of flexibility at most individual metabolic steps.

82 ion leads to a significant reduction in loop flexibility at the binding interface, but in a number of

83 s imply that the linker regions confer great flexibility between domains, which suggests that VSGs ca

84 counts for the differences in conformational flexibility between LEN and SMA.

85 lained in terms of redundancy and regulatory flexibility, but it has remained unclear what signal-pro

86 hose perturbations and (ii) optimizing those flexibilities can be a possible design strategy to obtai

87 d computational evidence that conformational flexibility can assist the emergence and subsequent evol

88 and differences in longevity and behavioural flexibility can help reconcile apparently contrasting re

89 such function may be critical for cognitive flexibility, clarifying its mechanisms will likely expan

90 traint with subsequent deficits in cognitive flexibility compared with male rats.

91 ether TPJ plays a role in different types of flexibility, compared to its limited role in perceptual

92 rocessing properties and inherent mechanical flexibility, conjugated polymer field-effect transistors

93 s either improved or reduced with increasing flexibility, depending on the material's pore size chara

94 improve fish productivity and offer greater flexibility during aquafeed production.

95 g robustness in the developmental stages and flexibility during the cell cycle.

96 od, to quantitatively measure changes in RNA flexibility during the nucleolar stages of 60S assembly

97 e hydration is fundamental to its structure, flexibility, dynamics, and function, but it has been cha

98 and examined its effect on other domains of flexibility (economic/perceptual).

99 Our maps of nucleotide flexibility enable making predictions about the establis

100 e (PikAIII-TE) to impart increased substrate flexibility, enabling the production of diastereomeric m

101 ogether with its solution processability and flexibility, endow it with the capability of driving a n

102 al pore size/chemistry and minimal intrinsic flexibility even though other nonoptimal materials' sele

103 Due to this flexibility, flexible CCS generators provide system bene

104 The qudit system may offer great flexibilities for quantum information processing.

105 A shorter lead time would provide valuable flexibility for decisions about when to stop use of OPV

106 s lead to reduced turnaround time and retain flexibility for integrating different specimen types.

107 orted functionalization approach opens great flexibility for the targeted synthesis of multifunctiona

108 in terms of buffer compatibility and ensued flexibility for various applications.

109 We found that cognate metal binding altered flexibility from the N terminus through helix 1 and modu

110 Enhanced flexibility has been inferred from improved working memo

111 Trophic flexibility has been proposed as a mechanism facilitatin

112 in that they do not change side-chain size, flexibility, hydropathy, charge, or polarizability.

113 Specifically, it provides the flexibility (i.e. the indexing) needed to support the wi

114 phonemic fluency, working memory, cognitive flexibility, immediate and delayed recall, verbal learni

115 To obtain systematic insight into how the flexibility impacts this type of separation, we develop

116 es not only are beneficial to the mechanical flexibility improvement but also contribute to sunlight

117 loops but even with this location additional flexibilities in the molecule can mask the contribution.

118 We explored bees' behavioral flexibility in a task that required transporting a small

119 icolimbic activity associated with cognitive flexibility in abstinent smokers was restored to the lev

120 system levels surveyed indicates a need for flexibility in budgeting for globally synchronized publi

121 e growth method developed here should enable flexibility in design of more sophisticated devices base

122 of WS2 layers could empower a great deal of flexibility in designing atomically thin optoelectronic

123 Such flexibility in dispersal patterns can allow individuals

124 umber of cases it can also trigger increased flexibility in distal loops in response to allosteric co

125 Flexibility in escape behavior may also add an element o

126 enter, whereas locking the SD3-SD4 interface flexibility in favor of an extended conformer increased

127 nt individual differences, birds also showed flexibility in foraging patterns, binge-eating less and

128 For flexibility in genotyping applications, SNPs polymorphic

129 atible DNA end configurations coupled with a flexibility in loading order, resulting in many possible

130 lapping binding sites and the conformational flexibility in multi-specific ligand assemblies have not

131 in vivo and highlights the importance of MT flexibility in N-C coupling and neuronal-branching regul

132 dielectric substrate, thereby enabling more flexibility in polarization manipulation.

133 cts often require considerable ingenuity and flexibility in seeking behavior, which, by definition, p

134 This greatly extends the flexibility in selecting the conjugation site in express

135 in design algorithms, which model continuous flexibility in sidechain dihedrals, to model continuous,

136 of the linker allowed caspase-6 to gain more flexibility in the 130s region and in the L2 region conv

137 to model continuous, appropriately localized flexibility in the backbone dihedrals varphi and psi as

138 erved in other A2AR structures, highlighting flexibility in the binding pocket that may facilitate th

139 These results highlight the role of flexibility in the biology of real organisms and the eng

140 ss the role of OS-induced changes in protein flexibility in the context of changes in the mechanism o

141 f the Cre tetramer and that this, along with flexibility in the DNA, enable the engineered enzyme and

142 network model) highlights the importance of flexibility in the entrance region.

143 open transition is foreshadowed by segmental flexibility in the native state as probed by heteronucle

144 prediction tool, but also gives researchers flexibility in the number of genes analyzed at a time, w

145 at the foraging locus creates diversity and flexibility in the regulation of gene expression, and ul

146 ing, difficulties in refocusing, and lack of flexibility in the selection of column dimensions and fl

147 Notable flexibility in the substitution patterns, readily availa

148 the degree of freedom which can provide more flexibility in tuning the bandgap and also reduces the g

149 The use of large M12 L24 MOCs enables great flexibility in tuning this ratio, which provides access

150 The flexibility in using different energy pathways may indic

151 or as reward contingencies change (cognitive flexibility) in a probabilistic reversal learning task.

152 xidative reactions, respectively; the supply flexibility index quantifies overall flexibility of ATP

153 terminal portion of gp7 shows conformational flexibility, indicating an induced fit on binding to the

154 nics and electrostatics, that the changes in flexibility induced by ligand binding play an important

155 rovements provide a framework engineered for flexibility, intended to support these requirements as w

156 ly arranged glycine residues suggesting that flexibility is a key feature for pump activity.

157 Metabolic flexibility is defined as the ability to adapt substrate

158 rts the idea that active site conformational flexibility is essential to the acquisition of broader s

159 In the destabilizing P405M mutant, increased flexibility is evident throughout the first subdomain, s

160 a new framework to understand how behavioral flexibility is grounded in the appropriate balancing of

161 This and FRET confirm that flexibility is interrogated early during the interaction

162 Previous studies suggest that flexibility is mainly subserved by the dorsolateral pref

163 s (MOFs) such as gas storage and separation, flexibility is often seen as a parameter that can tune m

164 An important consequence of this flexibility is that the same enzyme reaction can occur v

165 uffer a characteristic deficit in "cognitive flexibility." It has been suggested that neurodegenerati

166 Their flexibility limits both the number of high-resolution st

167 tal mechanisms for cognitive and behavioural flexibility make a causal functional contribution to the

168 sional rigidities and intersubunit torsional flexibility measured experimentally with purified protei

169 an attractive way to improve the quality of flexibility modeling.

170 Our study reveals that IFNAR1 flexibility modulates ligand-binding affinity, which, in

171 n biological experiments while retaining the flexibility needed for experimental settings.

172 agellar geometry that minimizes the critical flexibility number at which buckling occurs.

173 A key dimensionless group called the flexibility number measures the hook flexibility relativ

174 In the WT domain, dynamic flexibility occurs at the N-terminus and the first alpha

175 The innate flexibility of a DNA sequence is quantified by the Jacob

176 ol to probe the impact of the conformational flexibility of Ar-Au-Ar intermediates, via systematic mo

177 These simulations revealed how the flexibility of ATAD2A's major loop, the so-called ZA loo

178 supply flexibility index quantifies overall flexibility of ATP supply; and the bioenergetic capacity

179 These structures illustrate the flexibility of binding to sequences outside of-but adjac

180 The structural dynamics and flexibility of cell membranes play fundamental roles in

181 Here we combine the flexibility of chemical synthesis with the specificity o

182 A reminder can temporarily renew flexibility of consolidated memories, referred to as rec

183 We conclude that the flexibility of decision-making implies that the strategi

184 nal organization, a process that enables the flexibility of declarative memories, are both hippocampu

185 Using the functional flexibility of DNA origami in conjunction with the struc

186 Mechanical flexibility of electronic devices has attracted much att

187 We focus on the fact that the flexibility of emotional responses and the nature of app

188 nctionals sacrificing physical rigor for the flexibility of empirical fitting.

189 execution (no reagents need to be added) and flexibility of fabrication of the device, together with

190 rials has proven an effective way to achieve flexibility of functional electronic devices.

191 Our results further illustrate the enormous flexibility of HIV-1 in counteracting human defense mech

192 critical for Lys-155 because of the inherent flexibility of its side chain.

193 Furthermore, individual differences in flexibility of local efficiency of R dACC/MFG significan

194 We discuss also the coordination flexibility of native CDs to metal ions in CD-based meta

195 It appears that reducing the flexibility of native Tm coiled-coil structure decreases

196 However, little is known about the flexibility of NB-LRR R genes to switch resistance speci

197 The flexibility of ncRNA provides a challenge for probing th

198 We demonstrate the flexibility of our approach by applying it to a problem

199 For confirmation, we exploited the flexibility of our system, enabling tamoxifen inducible

200 Given the distance requirements of HA, the flexibility of PEG scaffolds is too high to raise the ef

201 This review underscores the conformational flexibility of porphyrinoids, a unique class of function

202 map the local changes in the conformational flexibility of procaspase-6 at the discrete states that

203 ation were attributed to solubility, and the flexibility of proteins secondary structure at the pH st

204 ith an arc-shaped aperture for enhancing the flexibility of quick DNA and PCR detection.

205 However, the inherent flexibility of the "elbow" regions, which link the const

206 The flexibility of the 3-fold screw conformation of xylan in

207 bservations, together with the global higher flexibility of the AHR PAS-A and its loosely packed stru

208 fers a distinct advantage in sensitivity and flexibility of the application.

209 Flexibility of the approach is further validated by addi

210 Benefits included the flexibility of the approach, the high levels of engageme

211 hypothesize that some mutations increase the flexibility of the Cre tetramer and that this, along wit

212 nsures the high mechanical strength and good flexibility of the developed aerogel.

213 est that oligomer dissociation and increased flexibility of the dimer contribute to the enhanced chap

214 helicase-loading intermediates increase the flexibility of the DNA sequence requirements for origin

215 ed on a foil exploited the transmittance and flexibility of the gold foil.

216 Our analysis revealed that the flexibility of the helix 3, 7, and 11 regions represents

217 ns that may arise from the interplay between flexibility of the interacting blocks and entropic effec

218 hilst also retaining extensibility to ensure flexibility of the keratin filament network in the diffe

219 The stability and flexibility of the method are demonstrated with stochast

220 ly structured RNAs suggest that reducing the flexibility of the minimally structured RNA leads to red

221 lecular rotation at low temperatures and the flexibility of the molecular axle made of conjugated p-(

222 his interaction is lost, and leads to higher flexibility of the protein and potentially to the dimer-

223 Flexibility of the substrate-kinase interaction enabled

224 ely abolished transport and reduced backbone flexibility of the switch loop, which adopted a conforma

225 Enhancing the flexibility of the target DNA or prebending it increases

226 hed amino acid valine impairs the structural flexibility of the TMD in terms of alpha-helix/beta-shee

227 The intrinsic flexibility of the TRXL domains of UGGT may therefore en

228 A cryo-EM reconstruction reveals interdomain flexibility of the TRXL domains.

229 ealed a significant difference in the global flexibility of the two variants.

230 rsisted on earth perhaps 3Ga, leveraging the flexibility of their distinctive lifestyle to adapt to a

231 entated coparental bond; and demonstrate the flexibility of this bond across family constellations an

232 for tumour cells highlighting the metabolic flexibility of this cancer.

233 the PtdCho ligand is accompanied by loss of flexibility of two helix/loop regions, as well as of the

234 nto regulatory mechanisms and conformational flexibility of uPA and trypsin-like serine proteases in

235 ing into account the effect of subtle ligand flexibility on the electronic structure.

236 vely, conferring the rigidity on the rod and flexibility on the hook.

237 ry and displays switching dynamics and areal flexibility over timescales relevant for task performanc

238 d SERS substrates exhibit excellent SERS and flexibility performance.

239 Moreover, when the task environment requires flexibility, performance under SD suffers dramatically.

240 nd surprise are both associated with network flexibility - positive mood portends a more flexible bra

241 ut platform while retaining a high degree of flexibility, potentially also for other high-throughput

242 ique balance between cognitive stability and flexibility present in each individual.

243 TPJ: a combined DLPFC/TPJ activity predicted flexibility, regardless of domain.

244 he human EC represent space with an enhanced flexibility relative to neurons in rodents because they

245 led the flexibility number measures the hook flexibility relative to the thrust exerted by the flagel

246 With its high flexibility, reliability, and portability, the developed

247 diseases characterized by declined cognitive flexibility.SIGNIFICANCE STATEMENT Activation of the hum

248 als that a subtle interplay between backbone flexibility, steric factors, and ability to hydrogen bon

249 e the later deletion even improved cognitive flexibility, strengthened synaptic plasticity and induce

250 Using a cognitive flexibility task, we show that a set of brain regions co

251 effects of aneuploidy confer an evolutionary flexibility that may contribute to the aggressive growth

252 he envelope (E) protein exhibited particular flexibility, the highly conserved envelope domain II (ED

253 Due to its efficiency, scope, and flexibility, the newly developed SNP array will be very

254 e PON1's active site shape, volume, and loop flexibility, their largest effect is in altering the sol

255 r increases design freedom and manufacturing flexibility, thereby enabling complex geometries, increa

256 relations between light-chain conformational flexibility, thermodynamic stability and amyloidogenicit

257 radrenaline is believed to support cognitive flexibility through the alpha 2A noradrenergic receptor

258 S indicate an overall reduction in molecular flexibility throughout the protein, with significant str

259 dye conjugate with superior sensitivity and flexibility to any of the previously commercially availa

260 This application has the power and flexibility to be resident on a local computer or serve

261 bound conformations, and use this structural flexibility to bind specifically to multiple partners.

262 intain high processivity and yet possess the flexibility to bypass obstructions in template DNA.

263 integrated relational design that allows the flexibility to capture any type of electronic data (to d

264 e opinion for some time without losing their flexibility to change it in the long run.

265 Theory predicts that flexibility to changes in both reward values and transit

266 We demonstrate that flexibility to contingency changes can distinguish MB an

267 ances in nanotechnology provide unparalleled flexibility to control the composition, size, shape, sur

268 e aging physician while leaving institutions flexibility to customize the approach.

269 gines, and transmission expansion to provide flexibility to enable up to 50% of wind power penetratio

270 However, modulating network flexibility to enhance learning requires an understandin

271 rallel execution on clusters, and restricted flexibility to extend the underlying logic program.

272 DLM produced unbiased estimates and added flexibility to identify windows.

273 This phenomenon may provide flexibility to manipulate the electrical output from lig

274 4 is required for regulating guard cell wall flexibility to mediate the heat response in Arabidopsis.

275 cytoskeleton proposed to confer strength and flexibility to neurons and to participate in ion channel

276 erent nutrient sources, cells gain metabolic flexibility to survive periods of starvation.

277 h levels of CGC inhibition providing further flexibility to the MF --> CGC pathway.

278 etrical parameters of the SRR which provided flexibility to tune the SRR probe.

279 ures of goal-directed planning and cognitive flexibility to underlying resting-state functional conne

280 ortin alpha3 uses its greater conformational flexibility to wedge the RCC1 beta-propeller flanking th

281 ning the structure with different amounts of flexibility, transforming a protein into membrane coordi

282 nd general mechanism for conferring temporal flexibility upon sensorimotor and cognitive functions.

283 ed restraint stress and subsequent cognitive flexibility was examined in adult male and female rats.

284 priority triage with enhanced operating room flexibility was instituted to reduce scheduling wait tim

285 Finally, modification of intramolecular flexibility was shown to play a role in optimizing the b

286 To understand the neural basis of such flexibility, we recorded from the medial frontal cortex

287 Cas9/TRBO-sgRNA platform demonstrated sgRNA flexibility, we targeted the N. benthamiana NbAGO1 paral

288 out higher prediction quality of the residue flexibility when compared with the classical GNM and the

289 le circadian oscillators may provide greater flexibility when faced with conflicting environmental si

290 es to bridge the gap between scalability and flexibility, where 32 to 128 channels per probe were imp

291 ce of selectivity on a framework's intrinsic flexibility whereby performance is either improved or re

292 reduction of TTF moieties changes the linker flexibility, which in turn switches the breathing behavi

293 ecificity has been hampered by its intrinsic flexibility, which is facilitated by a 75-residue linker

294 ation could provide neurogenic programs with flexibility, while allowing for synchronous neuronal dev

295 evels of physical activity predict metabolic flexibility, while physical inactivity and sedentary beh

296 glucose and insulin, and a loss of metabolic flexibility with decreased lipid oxidation.

297 ng glucotoxicity, which reinstates metabolic flexibility with restored preprandial lipid oxidation an

298 sited epitaxially on a gold foil also showed flexibility, with the nanowires intact up to 500 bending

299 reative management, and, above all, personal flexibility-with not too much long-term planning.

300 meet demands for cryptographic usability and flexibility without sacrificing confidence.