ライフサイエンスコーパス: fly

1 redicted to be substrates for ICMT (ste14 in flies).

2 flies was surprisingly low (mean, 24% of fed flies).

3 three eukaryotic species: human, yeast, and fly.

4 ing surrogate models that are trained on the fly.

5 k that can classify cell cycle status on-the-fly.

6 undergoes a complex life cycle in the tsetse fly.

7 g to extend survival of V. cholerae-infected flies.

8 el algorithm for tuning fixation saccades in flies.

9 n yeast and organismal lifespan in worms and flies.

10 e patches that govern infectiousness to sand flies.

11 shaping the gut community structure of these flies.

12 espiratory function and proteostasis in aged flies.

13 to increased pathogen susceptibility in aged flies.

14 od-feeding female Lutzomyia longipalpis sand flies.

15 ave been implicated in lifespan extension in flies.

16 partially resembling that seen in the Bully flies.

17 er they underlie moist-seeking by dehydrated flies.

18 high-frequency response also in dark-adapted flies.

19 t not slow-moving, visual stimuli in walking flies.

20 n early life, extends the health and life of flies.

21 nted on a high-protein diet and in FoxO-null flies.

22 and p62 was notably reduced in draper mutant flies.

23 s to low frequencies typical of dark-adapted flies.

24 ed pheromone release, which attracts healthy flies.

25 ut unbiased screens to map reward neurons in flies.

26 HTTex1 aggregation both in larvae and adult flies.

27 some cases firing profiles in wake-behaving flies.

28 the escape response neural circuit of adult flies.

29 s exhibited checkerboard distributions among flies.

30 egulate expression of X-linked genes in male flies.

31 All patients infected sand flies.

32 water (77%), child hands (43%), food (58%), flies (50%), ponds (97%), and soil (95%).

33 A recent study reveals how flies achieve their remarkable aerodynamic agility with

34 ribution reduces the expected number of sand flies acquiring parasites, it increases the infection lo

35 on the northern Gulf of Mexico coast before flying across the Gulf.

36 TCT, and plays a crucial role in protecting flies against systemic Escherichia coli infection.

37 Visual motion sensing neurons in the fly also encode a range of behavior-related signals.

38 based predictions are fast enough for on-the-fly analysis in an imaging flow cytometer.The interpreta

39 ophila melanogaster S2 cells and adult fruit flies and results in increased SG formation.

40 behavioral phase resetting in cry(03) mutant flies and sensitively reports GFP-CRY expression.

41 More specifically, infected flies and their frass emit dramatically increased amount

42 ach is important for dry-seeking by hydrated flies and together they underlie moist-seeking by dehydr

43 veral types of axons for the lifespan of the fly and block the pro-degenerative effects of activated

44 ethods to predict protein function on yeast, fly and human protein datasets, and compare with four pr

45 uli, SCs in the intestinal epithelium of the fly and in the tracheal epithelium of mice exhibit trans

46 findings based on studies in tunicate, worm, fly and vertebrate cells have revealed that the mechanis

47 mon organizational principles with the adult fly and vertebrate visual systems.

48 ally distant blood-seeking predators, Stable fly and Wolf, while evoking avoidance responses in the p

49 Stopovers demand more time than flying and are used by individuals to refuel during migr

50 resolution in Drosophila melanogaster (fruit fly) and Danio rerio (zebrafish) to quantify signaling c

51 in-2 suppresses TDP-43 toxicity in yeast and flies, and intermediate-length polyglutamine expansions

52 (IIS) can extend healthy lifespan in worms, flies, and mice, but it can also have adverse effects (t

53 elevated IIS in cultured human cells and in flies, and to rescue age-related loss of GJs and of GFS

54 ng the coordinate space into regions, on-the-fly, and balancing computational effort between regions

55 he human brain updates specific goals on the fly, and translates those updates into choices, have rem

56 We found that human, fly, and yeast profilin homologs all directly enhance mi

57 Flying animals of different masses vary widely in body p

58 Heme deprivation in the tsetse fly anterior midgut might represent an environmental sti

59 otion is critical for animal navigation, and flies are a prominent model system for exploring this ne

60 Flies are expert at navigating cluttered environments, a

61 Phlebotomine sand flies are hematophagous insects that harbor bacterial, v

62 These diving flies are protected by an air bubble that forms around t

63 vior, but examples of such behavior in fruit flies are rare.

64 ng development, with the phenotype lost when flies are reared at 19 degrees C.

65 We demonstrate that adult Drosophila flies are susceptible to C. burnetii NMII infection and

66 Barnacles and fruit flies are two prominent model marine and terrestrial rep

67 demonstrate that gut microbes from the sand fly are egested into host skin alongside Leishmania para

68 lori, thereby demonstrating the potential of flies as proxies for environmental and public health sur

69 ical material and difficulties of the tsetse fly as an experimental system, very limited information

70 -conophthorin produced by the goldenrod gall fly as the specific chemical component that elicits this

71 vertical motion of the air in which they are flying, as a succession of fair-weather convective cells

72 Coal fly ash (CFA) is a by-product of coal combustion that ca

73 Coal fly ash (CFA) is a byproduct of coal combustion and is a

74 Analysis of some waste incinerator fly ashes revealed a significant difference between thei

75 To analyze these phenomena, surrogate fly ashes were synthesized to mimic the presence of thei

76 he TbHrg KO developed normally in the tsetse flies at rates comparable with wild-type cells.

77 ly more attractive to 50% of the female sand flies at the end of infection compared to before infecti

78 ly more attractive to 75% of the female sand flies at the end of infection.

79 Indeed, flies avoided dry heat more robustly than humid heat, an

80 ids the sudden changes in the beam location (fly-back distortion) present in conventional raster scan

81 new study recording from the hippocampus of flying bats has revealed populations of neurons tuned to

82 an immune response and in neurons to control fly behavior following infection.

83 ino acid oxidase (LAO) for selective "on the fly" biodetection of D and L-amino acids (AAs), respecti

84 o spectroscopically analyze brains from free-flying birds and link the results to OC exposure and con

85 ntroduced into mammalian skin through a sand fly bite, but different species cause distinct clinical

86 the possible effect of multiple exposures to fly bites on transmissibility has not been addressed.

87 ve proven to be effective in preventing sand fly bites, and subsequently infection.

88 In contrast to wild-type flies, both Arf6 and Efa6 mutants preferred alcohol-cont

89 We report that in the adult fly brain the mRNA encoding Orb2A protein exists in an u

90 An anatomical atlas of the central adult fly brain was recently described [12]; however, combinin

91 llipsoid body, a doughnut-shaped part of the fly brain, is essential for visual working memory.

92 e control of rapid steering maneuvers in the fly brain.

93 t virus, and was found at high titers in bat flies but not in blood or on mucosal surfaces of host ba

94 ers, were also rhythmically induced in young flies by constant exposure to exogenous oxidative stress

95 ses to fatty acids in IR25a and IR76b mutant flies can be completely rescued by expression of respect

96 OX3097D-Bol olive fly carries a fluorescent marker (DsRed2) for identifica

97 the APOL1 G0 or G1 transgene in nephrocytes, fly cells homologous to mammalian podocytes, induced inc

98 representing 1,042 genes in the drosophilid fly, Chymomyza costata Fully grown, third-instar larvae

99 The fly circuit assigns similar neural activity patterns to

100 In flies, compensation involves recruitment of the male-spe

101 vsRNAs, purified from haemolymph of infected flies, confer passive protection against virus challenge

102 erbirds of Australian desert ecosystems that fly considerable distances to find temporary water bodie

103 Flies continued to search around the original location,

104 gated whether blood meals from hematophagous flies could be used to identify the infectious agents ci

105 elop a simpler experimental approach wherein flies could implement behavior that induces self-stimula

106 Sexual arousal in flies counteracts the effects of sleep deprivation.

107 Like the fly counterpart, human p53 transcriptionally activated a

108 hough secondary ocular blast injuries due to flying debris are more common, primary ocular blast expo

109 of sample, a simultaneous and rapid "on-the-fly" detection (2 min) with high sensitivity (limits of

110 te for the D. melanogaster CTD in supporting fly development to adulthood.

111 sures that germline stem cells in male fruit flies divide to produce two sibling cells that are equal

112 Canopy RTMs (PROSAIL and FLiES), driven by these three factors combined, simulate

113 ting field abundance of the rainforest fruit fly Drosophila birchii to ecological change across gradi

114 substrates of reward perception in the fruit fly Drosophila melanogaster prompted us to develop a sim

115 we demonstrate that mate choice in the fruit fly Drosophila melanogaster results in the linear sortin

116 A study in the fruit fly Drosophila melanogaster shows that satellite DNA, an

117 haviour in many species, including the fruit fly Drosophila melanogaster.

118 These turns can be measured in tethered flying Drosophila [3, 4, 9], which facilitates the study

119 electrophysiological recordings in tethered flying Drosophila, we have identified a descending neuro

120 e contact insecticidal activity toward fruit flies (Drosophila melanogaster) indicates that Form II i

121 ility of bacterial colonization in the fruit fly (Drosophila melanogaster) gut.

122 m is highly reminiscent of that of the fruit fly, Drosophila melanogaster Altogether, our work unveil

123 In the fruit fly, Drosophila melanogaster, aversive olfactory learnin

124 Research using the fruit fly, Drosophila melanogaster, has helped us understand t

125 with perturbations that are computed on-the-fly during experimentation.

126 he method makes feasible the generation of a fly egg chemical profile database against which the DART

127 Here, we measured signals from free-flying Egyptian fruit bats and discovered a systematic a

128 cation of PRC1-Br140 "bivalent complexes" in fly embryos supports and extends the bivalency model pos

129 PRC1-Br140 bind developmental genes in fly embryos, with analogous co-occupancy of PRC1 and a B

130 The remarkable alkali fly, Ephydra hians, deliberately crawls into the alkalin

131 Fruit flies evolved in tropical regions under stable light-dar

132 ter discovering a small drop of food, hungry flies exhibit a peculiar behavior in which they repeated

133 ily homolog in Drosophila, Coxiella-infected flies exhibit reduced mortality from infection.

134 In the fly eye, the random mosaic of color-detecting R7 photore

135 e coordinated to drive dve expression in the fly eye.

136 ecies included representatives from the blow fly family (Calliphoridae), specifically Calliphora vici

137 The bites of uninfected sand flies favor the transmissibility of L. donovani by infec

138 Flies feed on liquid food from a microcapillary, and con

139 Interestingly, providing on-the-fly feedback of the root mean square deviation with resp

140 es, it increases the infection load for sand flies feeding on a patch, increasing their potential for

141 During spring 2015, we flew fixed-wing UAS equipped with thermal sensors, imagi

142 ensemble of wing control muscles in intact, flying flies.

143 In contrast, male-female pairs of flies follow a distinct pattern, most notably characteri

144 in humans, is highly IFN inducible in black flying fox cells and contributes to cell-intrinsic contr

145 ozens of differentially edited sites between flies from each slope, correlate these changes with gene

146 fates shifts the innate color preference of flies from green to blue.

147 ent finding in patients and in the mouse and fly FXS models.

148 y visually active animals, including humans, flies generate both smooth and rapid saccadic movements

149 that combines Drosophila melanogaster (fruit fly) genetics with transcriptome analyses it was found t

150 s upon previously developed STARR-seq in the fly genome and CapSTARR-seq techniques in targeted human

151 However, the fruit fly has been exploited to recapitulate PD gene related d

152 The house fly has sex chromosomes that resemble the ancestral fly

153 We show that autophagy-deficient flies have a systemic innate immune response that promot

154 Here, the authors report that middle-aged flies have more elongated, or 'hyper-fused' mitochondria

155 tsh induces a homeotic transformation of the fly head into thoracic structures.

156 ligase Nedd4 Analysis of embryonic and adult fly heart revealed that the Nedd4 protein regulates hear

157 lates heart development in Drosophila Larval fly hearts overexpressing miR-1 have profound defects in

158 ow that the aerial attack of the tiny robber fly Holcocephala fusca is consistent with the CBA model.

159 ion in more detail, we focused on Cindr, the fly homolog of the human NS gene CD2AP.

160 Free-flying honeybees exhibit remarkable cognitive capacities

161 Both fly host species segregate based on principal coordinate

162 the new possibility of a continuous, on-the-fly, IFE target fabrication process, employing sequentia

163 The development of the tsetse fly immune system relies on a cue from an endosymbiotic

164 To determine if fruit flies implement filtering driven by background optic flo

165 When bats flew in pairs, each bat responded to the presence of the

166 to deliver behaviorally triggered stimuli to flies in a feedback-loop mode, and are highly customizab

167 Bat flies, in particular, are highly specialized obligate he

168 cient Indian tradition is postulated to have flown independently of the Indus River into the Arabian

169 idae, genus Ledantevirus) in nycteribiid bat flies infesting pteropodid bats in western Uganda.

170 eloped Lagrangian stochastic model of weakly-flying insect movements in the convective boundary layer

171 ortant pesticides that are strongly toxic to flying insects but not to most vertebrates.

172 It is known that flying insects create "white" in extremely thin layers.

173 For example, flying insects typically increase equatorial curvature b

174 ngs of these capacities cannot be studied in flying insects.

175 irection are likely to be shared with other, flying, insects.

176 vity of Pol III in the gut of adult worms or flies is sufficient to extend lifespan; in flies, longev

177 ely 100 million yr ago; therefore, the house fly is expected to have X and Y Chromosomes with differe

178 When the fly is presented with a simulation of flying past an ele

179 st flight, but limiting acuity loss when the fly is still.

180 sex chromosomes that resemble the ancestral fly karyotype that originated approximately 100 million

181 In the fly larval brain, earmuff (erm) uniquely functions to re

182 (brown kiwi, crab-eating macaque and Malayan flying lemur); eight updated genome assemblies; extended

183 1 in vivo We generated transgenic Drosophila fly lines expressing the human APOL1 wild type allele (G

184 developed a versatile set of LexAop-KZip(+) fly lines that can be used directly with the large numbe

185 r flies is sufficient to extend lifespan; in flies, longevity can be achieved by Pol III inhibition s

186 icable differences in the gut microbiomes of flies maintained on different diets, we found no evidenc

187 Although human disease modeling in flies may still be rather novel, recent advances in gene

188 essed at normal, endogenous levels, bound to fly microtubules and were post-translationally modified,

189 syndromes, can be effectively studied in the fly model system.

190 ial for DNA binding and are deleterious in a fly model.

191 n multiple models of HD, including mouse and fly models, neurons transfected with mHTT, HD iPSC-deriv

192 sses toxicity induced by PINK1 deficiency in flies, mouse cells, patient-derived fibroblasts, and ind

193 prises approximately 50 described species of flies, nearly all of which are obligate parasites of nes

194 non-cell-death (non-apoptotic) functions in flies, nematodes, and mammals.

195 tment but do not impair synaptic function in fly neurons.

196 eurodegeneration induced by loss of the sole fly Nmnat ortholog is also fully blocked by axed, but no

197 s optogenetic activation of neurons when the fly occupies a specific area of a behavioral chamber, an

198 frass emit dramatically increased amounts of fly odors, including the aggregation pheromones methyl l

199 An average of 8.5% of murres flew off in response to the UAV, but >99% of those birds

200 Most gulls flew off in response to the UAV, but returned to the nes

201 type-specific gene disruption techniques in flies often reduce gene activity incompletely or rely on

202 We discovered that the fruit fly olfactory circuit solves this problem with a variant

203 of genetically engineered OX3097D-Bol olive fly on three non-target organisms that either predate or

204 isms that either predate or parasitize olive flies, one from the guild of parasitoids (Psyttalia conc

205 We show that in male fruit flies, onset of the daytime siesta is delayed by ambient

206 In the fruit fly optic lobe, T4 and T5 cells represent the first dire

207 aters, we demonstrate that entanglement with flying optical qubits can be stored into any neighboring

208 Illumination of whole flies or specific tissues containing Caspase-LOV-induced

209 When flying or swimming, animals must adjust their own moveme

210 A screen identified pasilla, the fly ortholog of mammalian Nova-1/2, as a mediator of Orb

211 In flies overexpressing mutant Ras(Val12) and S100A4, there

212 We engineered strains that replace the fly p53 gene with human alleles, producing a collection

213 re is an additional light-sensing pathway in fly pacemaker neurons.

214 o quantify the probing behavior of the fruit-fly parasitoid Diachasmimorpha longicaudata (Braconidae)

215 en the fly is presented with a simulation of flying past an elevated object, the spike burst activity

216 an insightful constructionist viewpoint of a fly photoreceptor being an 'imperfect' photon counting m

217 A fly photoreceptor has achieved such a large dynamic rang

218 A computational fly photoreceptor model, which mimics the real phototran

219 Specifically, in a fly photoreceptor, this limit is set by the number of it

220 light-induced current of the Opn4-expressing fly photoreceptors was approximately 40-fold faster than

221 ipRGC photosensitivity are characteristic of fly photoreceptors.

222 t prior exposure to bites of uninfected sand flies potentiates their ability to transmit infection to

223 ecific area of a behavioral chamber, and the flies' preferential occupation of this area reflects the

224 from one-day post-eclosion to thirty-day-old flies, proving their ability to prevent the toxicity of

225 ood or skin as a source of infection to sand flies remains unclear, and the possible effect of multip

226 Reducing SERCA activity in THADA mutant flies rescues their obesity, pinpointing SERCA as a key

227 In aged flies, respiratory activity is compromised and the produ

228 new layer of miRNA complexity regulating the fly response to systemic fungal infection.

229 ponse between dark-adapted and light-adapted flies, resulting in high-frequency response also in dark

230 A new study in flies reveals novel neurons capable of multiplexing info

231 Studies of cultured mammalian cells, worms, flies, rodents, simians, apes, and even humans, all indi

232 icient version of the algorithm, "Read-Split-Fly" (RSF), which can detect non-canonical spliced regio

233 rough the different microenvironments of the fly s interior organs, the incessantly swimming trypanos

234 d targeted knockdown of hearing genes in the fly's auditory organ elicit abnormal aggression.

235 clock cells appear to be responsible for the fly's circadian neurons becoming active at different tim

236 Whereas the fly's escape jump has been well studied [8, 9, 13-18], t

237 e how visual references are selected for the fly's internal compass.

238 umption in neurons of the mushroom body, the fly's major memory centre.

239 sual navigation of clutter and to encode the fly's movements along near cardinal axes of thrust, lift

240 ional genomics approach to identify the sand fly salivary components that are responsible for the act

241 collected water, hand rinse, food, soil, and fly samples from 608 households.

242 Light-adapted rdgC mutant flies showed relatively high S936-TRP phosphorylation le

243 nalysis of feeding behavior in freely moving flies shows that IR60b limits the duration of individual

244 independently accounted for 1, 33 and 66% of FLiES-simulated EVI seasonality, respectively.

245 sleep and sex drives determines whether male flies sleep or court, and identify a subset of octopamin

246 h orthologous sequences from other divergent fly species.

247 ts parallel features of the respective donor fly species.

248 ne-content evolution of Y-chromosomes across fly species.While X-chromosome gene content tends to be

249 sequencing now confer huge advantages in the fly system when modeling human disease.

250 train with hTau inserted into the endogenous fly tau locus and expressed under the control of the end

251 xpressed under the control of the endogenous fly tau promoter, thus avoiding potential toxicity due t

252 Since fly telomere integrity is guaranteed by a different mech

253 Fly telomeres are protected by the terminin complex that

254 e more relevant behavioural parameters for a fly than abstract pattern properties.

255 In about 50% of mitochondria from old flies, the inner membrane organization breaks down.

256 consent from the readers, 12 CT colonography fly-through examinations that depicted eight polyps were

257 Sleep in flies thus appears to involve at least two distinct stag

258 le maximizing energy conservation during non-flying times.

259 up of core proteins identified originally in flies to coordinate epithelial planar cell polarity (PCP

260 is process we measured the work required for flies to enter and leave various aqueous solutions.

261 ments show that it is more difficult for the flies to escape from Mono Lake water than from fresh wat

262 appetitive behavioral responses of wild type flies to hexanoic acid reach a plateau at 1%, but decre

263 plays a central role in immunity from fruit flies to humans, and NF-kappaB activity is altered in ma

264 Many animals, ranging from vinegar flies to humans, discriminate a wide range of tastants,

265 self-association mechanism is conserved from flies to humans.

266 play conserved roles in renal function from flies to humans.

267 and electrophysiology in head-fixed walking flies to identify a different neural population that con

268 set the frequency response of light-adapted flies to low frequencies typical of dark-adapted flies.

269 We find a conserved role, from fruit flies to mammals, for L-type calcium channels in augment

270 Vaccination teams and frozen vaccine were flown to the outbreak settings.

271 is an error-prone process that opens up the fly to developmental defects and the potential of tumor

272 Moreover, exposure of a fly to novel odors evokes an alerting response that can

273 c choriomeningitis virus (LCMV), or the sand fly-transmitted arbovirus Toscana virus (TOSV).

274 el stimulus that initially interests a fruit fly turns into a familiar one.

275 Mutant flies unable to regulate Orco function through phosphory

276 ISCs coupled with tissue demand and in aging flies, underscoring the generality of this mechanism.

277 th learned associations to produce an on-the-fly updating of motivated behavior.

278 d by a form of path integration in which the flies use idiothetic cues to search near the location of

279 the infectiousness of patients for the sand fly vector of visceral leishmaniasis is linked to parasi

280 the availability of nutrients in the tsetse fly vector.

281 h as the height and velocity at which drones fly, viewing distance, unfavourable vantage points, and

282 mission of L. donovani from sick hamsters to flies was surprisingly low (mean, 24% of fed flies).

283 In Notum null flies, we find upregulated extracellular Wg ligand and n

284 By modifying candidate SNPs in transgenic flies, we show that the largest effect is caused by an a

285 on in colonization when individual germ-free flies were fed their own natural commensals (including t

286 Communities within flies were not random assemblages drawn from a common po

287 Bomblyiid flies were the most effective non-bee flower visitors.

288 te, and methyl palmitate, attracting healthy flies, which in turn become infected and further enhance

289 tput genes remained robustly rhythmic in old flies, while others lost rhythmicity with age, resulting

290 Microbiome profiling of wild-caught sand flies will be of great help in the investigating of poss

291 morphogenetic protein Dpp in the developing fly wing and that this is necessary for developmental si

292 we show that overexpression of miR-1 in the fly wing can paradoxically increase Notch activity indep

293 use precise data on over 50,000 Drosophilid fly wings to demonstrate unexpectedly strong positive re

294 In contrast, flies with a constitutively active immune system had mic

295 ole in the structure of the microbiota where flies with constitutive immunity defined the gut microbi

296 As transgenic flies with either allele aged, nephrocyte function decli

297 attern was accelerated in immune-compromised flies with higher bacterial load and gut cell death.

298 shells were photo-cured individually, on-the-fly, with precisely-actuated, millisecond-length (70 ms)

299 ts of 585 TFs in five species (human, mouse, fly, worm and yeast).

300 NA, yet the nature of the gene repertoire of fly Y-chromosomes is largely unknown.