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1 luminometer format, mixtures containing 1.0 fmol total luciferase were quantified from measurements
2 is 0.5 fmol/100 mug DNA, and the LOQ is 1.0 fmol/100 mug DNA, making it possible to quantify bis-N7G
3 umor lysates with a linear range of 0.05-2.0 fmol/mug of total lysate protein and with coefficients o
6 ease of NE in CMA at 16 Hz from 27.8 +/- 6.0 fmol/mg of tissue to 15.5 +/- 5.0, 12 +/- 3.0, and 10.0
7 urinary bladder (1.8 +/- 0.5 and 9.0 +/- 6.0 fmol/mg of tissue, respectively), and murine urinary bla
8 Detection limits (3SD) of 1.6, 3.2, and 7.0 fmol estimated from three procedure blanks were obtained
11 earity of the fifth isotopologue (i.e., 0.05 fmol on column) was dependent on the peptide and instrum
13 run time (4 min), limit of detection (0.055 fmol on column, 18.75 fmol/ml plasma), precision (relati
15 etection of melamine and Sudan I down to 0.1 fmol in water and toluene, respectively, using just 1 mu
18 n, achieving a detection limit of 55 pM (1.1 fmol), and the combined competitive-amplification latera
19 3.3 nM (+/-0.58), and receptor density, 10.1 fmol/mg (+/-0.64), was obtained with a saturation bindin
20 case, the sensitivity of the MS was about 1 fmol, which allowed us to achieve a spatial resolution o
21 s with concentrations down to 1 microM and 1 fmol of protein nondestructively probed within the excit
25 hat promotes cowpea ethylene production at 1 fmol leaf(-1) and triggers increases in the defense-rela
26 er assay (1 nM) and dynamic ranges between 1 fmol and at least 750 fmol (1-750 nM) were obtained.
35 tings allows rapid enrichment from 5 mL of 1 fmol/muL phosphoprotein digests and concentration into s
39 hophora cells at rates between 0.02 and 0.10 fmol h(-1) cell(-1) and down to extracellular concentrat
41 This assay can reach a detection limit of 10 fmol and an isolation rate of 90% for the antigen CFP-10
42 rm also displayed a limit of detection of 10 fmol for thrombin in five different human serum samples
44 ents had AGT activity levels of less than 10 fmol/mg protein with a continuous-infusion O6-BG dose of
45 for concentrations of peptides lower than 10 fmol/microL, is to wash matrix/sample spots after peptid
47 The limit of detection for thrombin was 10 fmol in buffer using the aptamer/ISET-MALDI-MS configura
51 a high density of AT(1) binding (1207+/-100 fmol/g), which peaked at 0.4 mm rostral to the calamus s
52 allows a detection limit between 30 and 100 fmol DNA with a macroscopic gold disc electrode of 1 mm
53 y high loading capacities, approximately 100 fmol for angiotensin I and approximately 50 fmol for ins
54 nts resulted in sensitivities as high as 100 fmol of glycoprotein and 0.1 muL of human blood serum.
56 f spiked melamine in liquid milk down to 100 fmol also highlights the suitability of our SHP-OP SERS
57 of RNase B was fully characterized using 100 fmol of tryptic digest on a three-dimensional ion trap m
59 er incubation and that levels as low as 0.11 fmol of TPP per cell could be detected, suggesting the h
61 5)I-labeled NmU (K(D) 364 pM and B(max) 1114 fmol/mg protein) was identified, and mRNA encoding NmU-1
63 increases in basal ECF ACh (from 105 to 118 fmol/min) and in the increase produced by atropine (from
65 ion per zone loaded for fluorescence was 125 fmol for fluorescein isothiocyanate-labeled bovine serum
67 cal hyperinsulinemia (15 +/- 3 and 87 +/- 13 fmol x min(-1) x 100 ml(-1) basal vs. last 40 min of cla
73 inear over a wide range (r > 0.99, 0.01-1384 fmol/muL), and sensitive (LLOD and LLOQ <1 fmol/muL).
74 mits of detection were determined to be 0.14 fmol for phenanthrene and 4 amol for caffeine and to a p
78 to over 3 mM (0.15 pmol) and 500 microM (15 fmol) for fluorescein and TRITC-tagged albumin solutions
82 t of 2 nM and maximum binding capacity of 18 fmol/10(6) cells, and (18)F-FES had a dissociation const
86 itive with a limit of detection (LOD) of 0.2 fmol and a quantification linearity range from 1 fmol to
88 loped a simple, sensitive (approximately 0.2 fmol on column) and specific GC-MS assay for the detecti
89 crol of liquid is required, as little as 1.2 fmol of trypsin can be detected by using the on-chip ass
93 wells, the limit of detection (LOD) was 7.2 fmol of DNA target, corresponding to a final concentrati
94 peptidases (degradation rate of 100 +/- 8.2 fmol min(-1) mg(-1)) but an excellent substrate for phos
95 ction for phosphopeptides is approximately 2 fmol, based on using matrix-assisted laser desorption/io
98 des were detected in a mixture containing 20 fmol of human growth hormone tryptic digest mixed with t
100 rays, a 2-D DNA array is used to detect a 20-fmol sample of in vitro transcribed RNA from the uidA ge
103 ulted in an increased dynamic range (15-2000 fmol on plate) and improved linearity (r(2) = 0.99).
104 ressed at similar levels (approximately 2000 fmol/mg) and bound the radioligand [(3)H]R(+)-7-chloro-8
106 issue)(-1)) relative to controls (234 +/- 21 fmol (mg tissue)(-1)), and sepiapterin elevated flow-med
108 n control animals, NET B(max) was 388 +/- 23 fmol/mg protein and HED heart uptake (HU) at 30 min was
109 uL) from the commercial TIV and 93.6% (57.23 fmol/muL) of the total H3 HA (61.14 fmol/muL) in purifie
111 hput assay for ACK1 capable of detecting 240 fmol per well of the kinase reaction product employing a
114 ic small RNA was detected in amounts of 0.25 fmol (i.e. concentration of 10 pM in a 25 microl reactio
116 o 66 kDa) with a detection limit of 8 and 25 fmol for verapamil and reserpine, respectively, and quan
121 to 250 pmol, with a limit of detection of 25 fmol on column for all analytes except 2-AG, noladin eth
122 Linearity was proven over the range of 25 fmol to 250 pmol, with a limit of detection of 25 fmol o
125 accumulation at a rate of approximately 250 fmol/min/cm2, reflecting the basal ATP release rate.
126 he method is able to detect as little as 250 fmol of target without using PCR and exhibits single nuc
128 ep with purified H3 HA captured 82.9% (55.26 fmol/muL) of the total H3 HA (66.69 fmol/muL) from the c
132 ted BK 1-5 (160 +/- 75 fmol/mL, vs 44 +/- 29 fmol/mL in controls) and angiotensin II (182 +/- 41 pg/m
133 e units or 500 nM bromophenol blue (BPB) (29 fmol) was achieved using only an optical microscope and
135 ass IV patients as determined by POCTs (>290 fmol/ml) nano-LC-electrospray ionization-FT-ICR-MS data
139 se-derived sphingosine-NDA were 9.6 and 12.3 fmol, respectively, and the limits of quantification wer
141 e as evidenced by the detection of 100 pg (3 fmol) of a test protein spiked into 1 microg of a comple
142 endogenous beta(2)AR in HEK293 cells (20-30 fmol/mg) caused a rapid and transient activation of ERK1
143 approximately 300 pM of DNA target, i.e. 30 fmol in a 100 muL sample) and excellent selectivity, all
144 n caused renal VDR levels to decrease to <30 fmol/mg protein in vitamin D-deficient mice and to appro
146 scope detection platform offered a LOD of 30 fmol and a dynamic range spanning 3 orders of magnitude.
148 f detection of the assay was found to be 300 fmol with the upper limit of the dynamic range at 5 pmol
150 n full scan mode, detection limits of 0.1-33 fmol were achieved for glycoloytic and tricarboxylic aci
151 ent Michaelis-Menten parameters of Vm = 0.34 fmol/s and kcat/Km on the order of 104 s-1 M-1, in agree
152 the limit of detection of the method was 34 fmol, which is a significant improvement in comparison t
155 direct measurement of sulfur with ICPMS (358 fmol) and protein (ranging from 7 to 15 fmol depending o
156 The results provide a detection limit of 36 fmol for step-scan SIR measurements of ferrocyanide.
158 lume of 50 microL, corresponding to only 380 fmol (3.97 ng) of the rK5 analyte being injected onto th
159 increased ACh concentrations from 81 to 386 fmol/min in control rats and from 137 to 680 fmol/min in
162 amounts of total labile iron (1.6-1.8 x 10-4 fmol/cell) or hemoglobin iron (18 000-19 000 x 10-4 fmol
164 AA cells (0.0016 x 10-4 versus 0.0004 x 10-4 fmol/cell; P =.01), but much lower than the mean amounts
166 asma brain natriuretic peptide levels (-19.4 fmol x ml(-1); 95% CI, -5, -34; p = 0.014) and improveme
168 1.6 +/- 27.4 versus LP n = 7, 445.7 +/- 27.4 fmol (mg glomerular protein)(-1), P < 0.01), but affinit
169 fication of FodU at a detection limit of 3-4 fmol, which is approximately 20-fold better than that fo
171 lso improved dramatically using SPE (8 and 4 fmol/ml) compared with organic extraction (25 and 18.75
174 The molecular weight determination of 40 fmol/microL apomyoglobin was determined in 3 s using a r
179 EAS-2B cells occurred at a median rate of 43 fmol min(-1) mg(-1) resulting in a mean half-life of 20
182 OD of the assay in a sandwich format was 450 fmol with a dynamic range spanning 2 orders of magnitude
185 ion limit was determined to be as low as 0.5 fmol in 80 microg DNA, corresponding to 9 adducts/10(9)
187 pable of reliably detecting as little as 0.5 fmol of protein, and protein differences down to +/- 15%
188 gnitude across the gradient (500 fmol to 0.5 fmol on column) and no systematic trend was observed for
191 race peptides at levels of approximately 0.5 fmol/microL in complex peptide mixtures with a wide dyna
192 tained in 10 mug of DNA hydrolysates was 1.5 fmol, which corresponded to 50 adducts/10(9) normal nucl
194 easurement of high quality IR spectra of 2.5 fmol of molecules confined to a 125 mum(2) beam spot.
196 for SMN1 and uidA target were 54.3 and 30.5 fmol, and when the probe ratio was 4:1, the LOD for the
199 imits of detection of 3.6, 1.6, 5.8, and 8.5 fmol for estradiol, androstendione, testoterone, and pro
200 observed with TM-AFM and CV coincide (2-8.5 fmol.cm(-)(2)), indicating that most-if not all-cbo(3) o
208 -8) M, consumes very little sample (< or = 5 fmol), and offers capillary interfaces with various sepa
210 cases (mean [SD], 16.2 [2.0] vs 29.6 [16.5] fmol/mg, respectively; P = .04) or with male and female
211 fmol for angiotensin I and approximately 50 fmol for insulin, were obtained with a 4.2 m x 10-microm
212 ected with a lower limit of approximately 50 fmol of complement and was sufficiently selective to dif
216 However, it was found that with less than 50 fmol of biotin-labeled nucleic acid, which corresponds t
217 apable of reliable detection of less than 50 fmol of the derivatives of S1P and DHS1P without signifi
218 ut a measurement is very small, less than 50 fmol, which would be a useful attribute for drug screeni
220 greater than 20,000 pg/mg creatinine (12,500 fmol/mg) between postnatal days 1-4 occurred among 54% o
221 of detection of the setup (approximately 500 fmol limit of detection for citric acid), improvements i
223 orders of magnitude across the gradient (500 fmol to 0.5 fmol on column) and no systematic trend was
224 for the total ion current peak areas of 500 fmol of angiotensin I were improved by a factor of 2.6 w
225 Bilateral NTS microinjection of SP (500 fmol) produced a similar selective attenuation of the ca
226 ng platform allowed for detection down to 53 fmol of Streptococcus pneumoniae tmRNA, equivalent to ap
227 ch prostaglandin was 20 pg/ml (0.20 pg, 0.55 fmol on-column), and the interday and intraday coefficie
230 (9.3 +/- 0.6, 10.1 +/- 0.5 and 10.3 +/- 0.6 fmol mg(-1) protein, respectively), but there were no so
231 vs. anxA4a(-/-): 5.1 +/- 0.3 vs. 6.7 +/- 0.6 fmol/microg protein) or FSK (anxA4a(+/+) vs. anxA4a(-/-)
244 43; NF LV, 32.89+/-5.38; NF RV 40.49+/-10.66 fmol/min per milligram (P<0.05 PPH RV versus PPH LV; P<0
245 found that human lung macrophages contain 66 fmol of this protein per 100 microg of cell protein.
247 % (55.26 fmol/muL) of the total H3 HA (66.69 fmol/muL) from the commercial TIV and 93.6% (57.23 fmol/
251 h a high degree of anti-HIV protection (>700 fmol/punch) were found in 42 (54%), 37 (47%), 38 (49%),
253 R(-/-) mice have elevated BK 1-5 (160 +/- 75 fmol/mL, vs 44 +/- 29 fmol/mL in controls) and angiotens
254 it of detection (0.055 fmol on column, 18.75 fmol/ml plasma), precision (relative standard deviations
259 12.9 +/- 0.9, 13.5 +/- 0.9 and 13.6 +/- 0.8 fmol mg(-1) protein, respectively) and Arg16+Gln27 havin
260 ring EFS of CMA (2.5 +/- 0.9 and 5.8 +/- 0.8 fmol/mg of tissue, respectively), canine urinary bladder
261 highest in the amygdala (B(max)=149.9+/-13.8 fmol/mg protein), thalamic, and hypothalamic nuclei.
264 numbers in both the stimulated (35.2 +/- 4.8 fmol acetylcholine receptor/mg protein) and nonstimulate
265 lower in arterioles from old rats (94 +/- 8 fmol (mg tissue)(-1)) relative to controls (234 +/- 21 f
268 tection of LD/LI/ToF-MS as low as [0.2, 2.8] fmol per laser pulse and we make quantitative prediction
269 ) = 7.62 +/- 1.18 nM, B(max) = 31.6 +/- 1.80 fmol/mg protein) that is distinct from fatty acid amide
271 al release of UDP-glucose and ATP (72 and 81 fmol/min/10(6) cells) combined with a rate of UDP-glucos
272 tly showed high TFV-DP levels (median, 1,810 fmol/10(6) cells) between 4 and 24 h that exceed the 95%
275 ates can be measured as low as 3.55 +/- 1.84 fmols(-1) in a 96-well plate format, and the assay has b
277 e concentration(50) values of 68, 45, and 87 fmol leaf(-1) for Vu-In, Vu-(E+)In, and Vu-(GE+)In, resp
278 initial reaction rates averaged 3.9 +/- 2.9 fmol AngII/min/ micro g protein with a mean maximal conv
279 4.7, and 1.93 ng/mg HSA (1010, 220, and 28.9 fmol BPDE equiv/mg HSA)--were significantly different (P
280 endothelin-1 (80 +/- 15.7 versus 29 +/- 3.9 fmol/kg body wt per d; P < 0.02) and of the NO metabolit
281 the series (intrathecal ED50 approximately 9 fmol per mouse), whereas in untreated mice its ED50 was
283 r format provided a limit of detection of 90 fmol and an upper limit of dynamic range of 3.5 pmol.
284 ut still significant increase (from 75 to 92 fmol/min, P<0.05), and elevated striatal ACh content (by
286 l-D-glucose uptake into erythrocytes was 996 fmol/10(6) red blood cells per second, significantly les
287 ective detection of the peptide biosensor at fmol levels from aliquots of cell lysate equivalent to ~
288 oteinase inhibitor proteins when supplied at fmol levels to young tomato plants through their cut ste
290 f unique, long oligonucleotides (150mers) in fmol amounts using parallel synthesis of DNA on microarr
292 marked increase in analytic sensitivity (low fmol/muL) and the identification of double bond position
294 aterial and has a detection limit in the low fmol range, and is thus the most sensitive method for di
295 ompounds with limit of detection down to low fmol levels, capability of analyzing small and large mol
296 ibody bead, (ii). detecting peptides at low (fmol) levels, (iii). producing MS/MS data of suitable qu
300 trochemical stripping transduction (to yield fmol detection limits) and with an efficient magnetic se
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