ライフサイエンスコーパス: focal

1 with these doses caused lethal GI syndrome, focal (5 mm) radiation of the intestine did not cause an

2 significantly less radiofrequency time than focal ablation (56+/-11 versus 497+/-110 seconds; P<0.00

3 ons, SAHA and cisplatin cotreatment promoted focal accumulation of the low-fidelity polymerase Poleta

4 The loss of podocytes triggers a focal activation of parietal epithelial cells, which sub

5 o predict the AF origins in association with focal activities.

6 ory conduction of multiple wavelets or rapid focal activity.

7 Focal adhesion <1500 mum was present in 87%.

8 e discovery rate (FDR) < 0.05], such as KEGG FOCAL ADHESION and KEGG AXON GUIDANCE, which had been de

9 ted by changes in mitochondrial positioning; focal adhesion assembly and stability was decreased in M

10 inner nuclear membrane protein Sun2 promote focal adhesion assembly by activating the small GTPase R

11 C complexes and inhibits RhoA activation and focal adhesion assembly.

12 n force to promote actin retrograde flow and focal adhesion assembly.

13 6 contributes to the integration of NCAM1 in focal adhesion complexes but, unlike cells lacking PrP,

14 roundings through modulating the activity of focal adhesion complexes.

15 d sensitivity to Mg(2+)- and Ca(2+)-mediated focal adhesion disassembly in metastatic cells, rather t

16 In turn, focal adhesion formation and FAK/SRC signaling is activa

17 robed in vitro and significant modulation of focal adhesion formation and osteochondral lineage commi

18 that plays critical roles in cell migration, focal adhesion formation, and is an important component

19 The lifecycle of a focal adhesion is a highly coordinated process involving

20 Specifically, the disruption of focal adhesion kinase (FAK) and paxillin interactions us

21 by a decrease in the phosphorylation of both focal adhesion kinase (Fak) and protein kinase B (Akt).

22 Focal adhesion kinase (FAK) and Src family kinases (SFK)

23 We identified focal adhesion kinase (FAK) as a VHR-interacting molecul

24 We previously identified focal adhesion kinase (FAK) as an important regulator of

25 we identify the adhesion proteins talin and focal adhesion kinase (FAK) as proteolytic targets of ca

26 n and a ligand resulted in the activation of focal adhesion kinase (FAK) in a protein kinase C depend

27 Focal adhesion kinase (FAK) is a nonreceptor tyrosine ki

28 suppresses autophagy and that activation of focal adhesion kinase (FAK) is necessary for PE-stimulat

29 Both Pyk2 and the closely related focal adhesion kinase (FAK) regulate tumor cell invasion

30 Inhibition of focal adhesion kinase (FAK) rescued SERT function in syn

31 ced phosphorylation of occludin Ser(490) and focal adhesion kinase (FAK) Ser(722) and Tyr(576).

32 we report that Src family kinases (SFK) and focal adhesion kinase (FAK) sustain AKT and MAPK pathway

33 this residue blocks PKD2's interaction with Focal Adhesion Kinase (FAK).

34 es several oncogenic pathways, such as early focal adhesion kinase activation upstream of PI3K-mTOR,

35 beta3 and the concomitant phosphorylation of focal adhesion kinase and AKT in podocytes.

36 ion of integrin-beta3 and phosphorylation of focal adhesion kinase and AKT, known mediators of integr

37 A induced cytoskeletal changes and activated focal adhesion kinase and ERKs 1/2, and decreased Src ki

38 We have found that focal adhesion kinase expression is downregulated under

39 Focal adhesion kinase is an intracellular protein kinase

40 sin light chain kinase or phosphorylation of focal adhesion kinase was ineffective.

41 ain of IGFBP-1, through integrin engagement, focal adhesion kinase, and integrin-linked kinase, enhan

42 mpaired by inhibitors of NADPH oxidase, Syk, focal adhesion kinase, and proline-rich tyrosine kinase

43 eral application, here we apply the model to focal adhesion kinase, which initiates the chemical sign

44 previously reported in separate studies that focal adhesion kinase-1 (FAK) and the chemokine receptor

45 cell motility itself, which instead utilizes focal adhesion kinase-fibronectin signalling.

46 Bis-T-23 promoted stress fiber formation and focal adhesion maturation in a dynamin-dependent manner.

47 f the essential and autonomous regulators of focal adhesion maturation suggests a molecular mechanism

48 k between the LRP4-MuSK pathway and integrin-focal adhesion pathway.

49 and alpha5beta1-specific blockade inhibited focal adhesion phosphorylation and IL-13-enhanced contra

50 ctin, inhibited ASM adhesion, and attenuated focal adhesion phosphorylation.

51 ather than changes in integrin expression or focal adhesion phosphorylation.

52 ation of extracellular matrix remodeling and focal adhesion processes in tumors with high TF, support

53 indlin-2, which is primarily recognized as a focal adhesion protein in EC, was not anticipated to hav

54 class of small molecules aimed at targeting focal adhesion protein interactions that are essential f

55 t that using small molecules to modulate the focal adhesion protein paxillin is an effective strategy

56 Src kinase-dependent pY14Cav1 regulation of focal adhesion protein stabilization, focal adhesion ten

57 lay a key role in regulating the activity of focal adhesion proteins.

58 in-mediated cell adhesion via the control of focal adhesion remodeling, and discuss how these emergin

59 Hic-5, a focal adhesion scaffold protein, has previously been imp

60 n cytoskeletal architecture and reduction of focal adhesion size and number, all of which were rescue

61 ion of focal adhesion protein stabilization, focal adhesion tension, and cancer cell migration is CSD

62 le of integrins in controlling cytoskeleton, focal adhesion, actomyosin contraction, and actin and mi

63 -activated protein kinases, tight junctions, focal adhesion, transforming growth factor-beta, vascula

64 the role of CD103 cytoplasmic domain and the focal adhesion-associated protein paxillin (Pxn) in down

65 dingly, BA caused an increase in the size of focal-adhesion-kinase/paxillin-positive peripheral adhes

66 tein p130Cas is a Src substrate localized in focal adhesions (FAs) and functions in integrin signalin

67 Focal adhesions (FAs) are integrin-based transmembrane a

68 Cells rely on focal adhesions (FAs) to carry out a variety of importan

69 ligands, and the colocalization of DLC1 with focal adhesions and attenuates tumor suppressor activity

70 -pen showed disruption of filamentous actin, focal adhesions and caveolae-mediated membrane trafficki

71 sion of pUL7-pUL51 is important to stabilize focal adhesions and maintain cell morphology in infected

72 scous response, during which it is lost from focal adhesions and recruited by the cadherin complex to

73 rthermore, Bis-T-23 induced the formation of focal adhesions and stress fibers in cells in which the

74 Focal adhesions are dynamic constructs at the leading ed

75 The presence and regulation of PKD2 at focal adhesions identifies a novel function for this kin

76 ation and synchronously stabilizing cellular focal adhesions in a high-tension mode, paralleling effe

77 he targeting of active phospho-Src away from focal adhesions into autophagic structures that cancer c

78 the extracellular matrix (ECM) occur through focal adhesions or hemidesmosomes via the engagement of

79 The assembly of focal adhesions requires the recruitment and activation

80 ytoskeleton, allowing forces exerted through focal adhesions to reach the nucleus.

81 thelial cells showed defective lamellipodia, focal adhesions, and repair after wounding, along with i

82 ated with decreased cell spreading, abnormal focal adhesions, changes in the organization of the acti

83 1 enhanced CSD-dependent vinculin tension in focal adhesions, dampening force fluctuation and synchro

84 ase in the number of actin stress fibers and focal adhesions, leading to enhanced cell migration.

85 of phospho-Src and phospho-FAK accumulate at focal adhesions, positively regulating adhesion and inva

86 When FAK is present, Ambra1 is recruited to focal adhesions, promoting FAK-regulated cancer cell dir

87 regulating the formation and disassembly of focal adhesions.

88 loss of wide F-actin stress fibers and large focal adhesions.

89 d this in turn blocks maturation of anterior focal adhesions.

90 sociates with alpha-actinin and localizes to focal adhesions.

91 coli protein is required for disassembly of focal adhesions.

92 actin stress fibers anchored in streak-like focal adhesions.

93 ed targeted delivery of integrin vesicles to focal adhesions.

94 in deposits via talin1, a major component of focal adhesions.

95 cells expressing paxillin-EGFP to visualize focal adhesions.

96 Focal adipose deficiency, such as lipoatrophy, lumpectom

97 to radial actin stress fibres of remodelling focal AJs.

98 The most frequent focal alterations in human retinoblastoma are mutations

99 n of the PPARgamma/RXRalpha heterodimer, and focal amplification/overexpression of PPARgamma converge

100 determine how time since disturbance in both focal and neighbouring source patches might affect metap

101 P < .001), diffuse and focal (P < .001), and focal and normal (P < .001) patterns.

102 76% for correctly identifying the origin of focal and re-entrant excitation with a spatial resolutio

103 Results suggest that both focal and source habitat history can influence recoloniz

104 cavitation produced an approximately 40-fold focal and sustained increase in ATP, the source of which

105 In cells from sham-operated animals, focal application of acetylcholine induced a left shift

106 In addition, focal application of GABA receptor antagonists to sensor

107 of lesions were functionally connected to a focal area in the dorsal medial cerebellum.

108 movement and replacement and locate putative focal areas for a set of tales that are spread worldwide

109 formation is a regulated process involving a focal assembly machine, rather than simple physical pert

110 Focal assembly of "viral transcriptional factories" decr

111 chanism for effective viral transcription by focal assembly of RNA polymerase II around Kaposi's sarc

112 es, its ability to discriminate the locus of focal attention is severely limited.

113 searchlight hypothesis argues for a role in focal attentional modulation through positive feedback,

114 unctionality are degraded in the presence of focal axonal swellings (FAS) arising from neurodegenerat

115 primary cultures accumulate lysosomes within focal axonal swellings that resemble the dystrophic axon

116 FOR A SCIENTIFIC COMMENTARY ON THIS ARTICLE: Focal brain injury can sometimes lead to bizarre symptom

117 We propose that focal breast cancer susceptibility, at least in part, or

118 sions and 21 women (age 34 to 66 years) with focal breast lesions were injected intravenously with MB

119 lis anterior muscle herniated and produced a focal bulge along the anterior aspect of the leg.

120 hat loss of a single factor (PHF6) can cause focal changes in chromatin accessibility and nucleosome

121 ce tree, facilitating systematics studies of focal clades.

122 Focal CNAs affecting the MYC gene and the PTEN gene were

123 which will lead to a better understanding of focal complications of brucellosis.

124 During cooling, toric focal conic domains arise through a sequence of morpholo

125 nvolving nematic stripes and locally aligned focal conic domains.

126 by TBI in two different injury mouse models-focal contusion and diffuse concussive injury.

127 istopathological diagnosis among adults, and focal cortical dysplasia was the most common diagnosis a

128 formations of cortical development in 19.8% (focal cortical dysplasia was the most common type, 52.7%

129 tionally had schizencephaly, heterotopia, or focal cortical dysplasia.

130 Focal cortical dysplasias (FCDs) are malformations of co

131 ectivity underlying normal visual processing.Focal cortical seizures result from local and widespread

132 nhibition over the perilesional tissue after focal cortical stroke in mouse forelimb motor cortex.

133 Focal cortical stroke often leads to persistent motor de

134 erstanding of the specific mechanisms of non-focal crop pesticide exposure is essential for minimizin

135 Landscape context strongly predicted focal crop pollen foraging and total pesticide residues,

136 Yet focal crop pollen foraging was a poor predictor of pesti

137 k was positively related to diversity of non-focal crop pollen sources.

138 llination services came from residues in non-focal crop pollen, likely contaminated wildflowers or ot

139 oints lower than the scores of patients with focal damage (beta = -6.15; 95% CI, -11.7 to -0.59; P =

140 ity are associated with their performance on focal dark adaptation (DA) testing and with choroidal th

141 e same day they underwent DA testing using a focal dark adaptometer measuring rod intercept time (RIT

142 transient recurrence of prior stroke-related focal deficits, admission magnetic resonance imaging sho

143 deletion (VAV1 Delta778-786) generated by a focal deletion-driven alternative splicing mechanism as

144 Focal deletions of the RanBP6 locus on chromosome 9p wer

145 multi-segmented optical needle with variable focal depth, adjustable interval, narrow lateral width,

146 er resurfacing (AFR) within treated areas of focal dermal hypoplasia (FDH).

147 ipsilateral to infarct after a delay with a focal distribution that is strongly linked to the initia

148 rogrammed strand-specific DNA mutagenesis at focal DNA/RNA hybrid structures, they make a convenient

149 Focal drivers were observed in 1 or both PV regions in 7

150 Patients with isolated focal dystonia evaluated within 5 years from symptom ons

151 architecture of the functional connectome in focal dystonia was analyzed in a large population of pat

152 motor manifestations of isolated adult-onset focal dystonias.

153 Seizure patterns identified in focal epilepsies caused by diverse etiologies are likely

154 rging from West syndrome (two patients), and focal epilepsies with an electrical status epilepticus d

155 t can bring seizure remission in people with focal epilepsy but requires careful selection of candida

156 in humans and in different animal models of focal epilepsy correlates with reduction of neuronal fir

157 Focal epilepsy involves excessive cortical activity that

158 tifactorial model of white matter atrophy in focal epilepsy is proposed.

159 In the Scn2a(Q54) mouse model of epilepsy, a focal epilepsy phenotype is caused by transgenic express

160 In patients with drug-resistant focal epilepsy requiring surgery, hippocampal sclerosis

161 ery is an effective treatment for refractory focal epilepsy.

162 ampled at 2,048 Hz in people with refractory focal epilepsy.

163 guage function for presurgical evaluation of focal epilepsy.

164 eizures and a long history of drug-resistant focal epilepsy.

165 e-II vesicles was an early event mediated by focal exocytosis and coincided with the recruitment of t

166 diffuse and late gadolinium enhancement for focal fibrosis were assessed.

167 lation system with differential illumination focal filtering, a variant of HiLo microscopy, which ena

168 dney biopsies obtained from individuals with focal glomerulosclerosis.

169 s, severe destruction of the vertebral body, focal/heterogeneous contrast enhancement of vertebral bo

170 arrested myelination in nerve development to focal hypermyelination in adulthood, depending on the le

171 1 hyperactivity in adult animals resulted in focal hypermyelination.

172 fibers may represent a potential vehicle for focal ictogenesis.SIGNIFICANCE STATEMENT We describe a n

173 However, there is a lack of focal IL-18R expression in their terminal field.

174 ptotic targeted ablation (2Phatal) that uses focal illumination with a femtosecond-pulsed laser to bl

175 Over a century ago, the focal infection theory implicated these infections in th

176 city for detecting chronic diffuse and multi-focal inflammation mediated by activated microglia/macro

177 effects and may find utility in systemic and focal inflammatory and ischemic disorders.

178 e potential of EVs, isolated from rats after focal inflammatory brain lesions using IL-1beta, to acti

179 tial relapsing-remitting clinical course and focal inflammatory lesions that have a predilection for

180 roglial/macrophage activation at the site of focal inflammatory lesions, presumably by preventing leu

181 In vivo focal infusion of GABA or GABA reuptake inhibitor to sen

182 ibutions of retrogradely labeled cells after focal injections of retrograde tracer into the inferior

183 Two types of injuries are investigated, focal injury caused by mechanical damage and diffuse inj

184 ) undergoing surgery for imperforate anus or focal intestinal perforation and isolated ENS cells.

185 Focal intimal disruption (FID) has been described in >20

186 mpairment; and (iv) individuals with notably focal involvement of the medial temporal lobe and a slow

187 Conclusion LSIRs due to focal iron deposits are detected in lymphoma lesions and

188 18 patients, LSIRs appeared to be related to focal iron deposits; this was proven with Perls staining

189 uroprotective effects were examined in mouse focal ischemia/reperfusion (I/R) model.

190 e and mild traumatic injury was inflicted by focal laser lesion and by mild photo-damage, respectivel

191 both who had evidence of retinal scatter and focal laser treatment).

192 Focal laser treatments declined from 188 351 procedures

193 77.8% (14/18) of patients had focal late gadolinium enhancement.

194 The focal length increases from 3.8 mm to 22.3 mm as the app

195 inates the imaging and explains the measured focal length of about one millimeter.

196 mpound micro-lenses with dynamically tunable focal lengths.

197 real or virtual images, and display variable focal lengths.

198 Following identification of a focal lesion by ultrasound surveillance, further investi

199 In the cortex, focal lesion changes might precede diffuse atrophy with

200 This study shows that focal lesions affect the brain's ability to represent st

201 While several studies have shown that focal lesions affect the communication between structura

202 itively associated with the size of biopsied focal lesions consistent with regional outgrowth of adva

203 emor, and dystonia involves the placement of focal lesions or the application of deep brain stimulati

204 Focal lesions were excluded based on structural magnetic

205 Focal lesions were placed in the optic tectum (OT) and i

206 te by biophysical modeling the origin of the focal LFP signature of the single-axon monosynaptic thal

207 (length 2.8+/-0.9 mm) were present in 53% of focal lines and 0% of linear ablation lines.

208 -IRDye800CW showed strong pancreatic uptake, focal liver uptake, and gastrointestinal uptake in the t

209 Focal localization is reinstated following re-expression

210 The main differences were (i) predominant focal (loss-of-function) versus generalized (gain-of-fun

211 Underestimation was because of focal LV hypertrophy (n=10; 10.3%) or poor acoustic wind

212 he function of TSC in the remyelination of a focal, lysolecithin-demyelinated lesion in adult male mi

213 Ocular findings were focal macular pigment mottling, chorioretinal atrophy wi

214 Persistent focal MBKDR binding on USMI was assessed.

215 volvement in the early-onset group, and more focal medial temporal lobe loss in the late-onset group.

216 ny of the following: chromosome 7 copy gain, focal MET or HGF gene amplification, or MET kinase domai

217 topoietic cells with DNMT3A(R882H) displayed focal methylation loss, suggesting that hypomethylation

218 activity in the hippocampus was modulated by focal microinjections of potassium chloride into the nuc

219 y and that PINK1 recruits Parkin proximal to focal misfolded aggregates of the mitochondrial-localize

220 enom peptide, is highly neuroprotective in a focal model of ischemic stroke.

221 had only a few seizures, 1 had more than 30 focal motor seizures, and 1 had 4 witnessed generalized

222 4,5-trisphosphate gradient, which guides the focal movement of Golgi-derived vesicles to the site of

223 ear (n=18) epicardial lines were longer than focal (n=8) epicardial lines (3.3+/-0.7 versus 2.1+/-0.9

224 : transient worsening of residual poststroke focal neurologic deficits or transient recurrence of pri

225 experiencing fevers, syncope or presyncope, focal neurologic deficits, chest pain, nausea, vomiting,

226 sory deficits (HR, 2.3; 95% CI, 1.3 to 4.0); focal neurologic dysfunction (HR, 4.9; 95% CI, 3.2 to 7.

227 95% CI 2.82 to 10.8, p<0.0001) and transient focal neurological episodes (OR 11.7; 95% CI 2.70 to 50.

228 e often clinically presenting with transient focal neurological episodes compared with cortical super

229 ted with decreased consciousness, fever, and focal neurological signs.

230 aemic attack, which is clinically defined as focal neurological symptoms of ischaemic origin resolvin

231 Although this focal neuronal death does not impact anxiety/depression-

232 hin psychomorphospace, the global versus the focal, now has a metric by which patterns of morphology

233 Focal optogenetic inhibition tiled across cortex reveale

234 and 3 were present in 36%, 55%, and 9%, and focal or diffuse ptc in 36% or 64%.

235 on is characterised by non-length-dependent, focal, or multifocal symptoms.

236 Twenty-four women (age 48 to 79 years) with focal ovarian lesions and 21 women (age 34 to 66 years)

237 n diffuse and normal (P < .001), diffuse and focal (P < .001), and focal and normal (P < .001) patter

238 In the present study, whether or not a focal participant cooperated previously affected the ove

239 ar RGC+IPL loss was determined by diffuse or focal patterns on SD-OCT-generated deviation maps (proba

240 3-6) injections, one of which also underwent focal peripapillary laser.

241 cal calcifications; (3) macular scarring and focal pigmentary retinal mottling; (4) congenital contra

242 e version of the BEPP, which is suitable for focal plane array detector (FPA)-based micro-FTIR analys

243 ment is based on the determination on a back-focal plane image of the critical angle separating evane

244 ets that generate excitation patterns in the focal plane of the detection lens.

245 Presence of focal plaque increased over time: from 8% to 15% in wome

246 olism, however, has recently re-emerged as a focal point of biomedical studies and, as a result, deve

247 a major feature of the Abeta40 fibrils and a focal point of mutations linked to early onset Alzheimer

248 s of viral diversity, with home location the focal point of transmission.

249 ics by adjusting the axial offset of the two focal points.

250 ved cold-responsive 'orthogroups' within our focal Pooideae species that originated successively duri

251 Dedifferentiated liposarcoma represents focal progression of well-differentiated disease into a

252 ereas major ascending projections, including focal projections to ventral hippocampus, ventrolateral

253 cused ultrasound is technically feasible for focal prostate ablation and appears to have a favorable

254 bortezomib is a novel therapeutic agent for focal radiation-induced osteoporosis.

255 structure and strength in mice at 4 wk after focal radiation.

256 Compared with sequential focal radiofrequency ablation in a linear pattern, an ir

257 o diamondlike carbon foils, electrons in the focal region of one foil are rapidly accelerated by the

258 l for understanding the relationship between focal reorganization in the sensorimotor cortex and ever

259 -focal retrograde amnesia; (iii) psychogenic focal retrograde amnesia following a minor neurological

260 tegorized as: (i) fugue state; (ii) fugue-to-focal retrograde amnesia; (iii) psychogenic focal retrog

261 were reevaluated for the extent (diffuse vs focal), score and leukocytic composition in relation to

262 kidney's filtration unit, a condition called focal segmental glomerulosclerosis (FSGS).

263 in glomeruli of patients with biopsy-proven focal segmental glomerulosclerosis (FSGS).

264 ) (referent) and lower for all other groups: focal segmental glomerulosclerosis (HR, 0.80; 95% CI, 0.

265 racterized by skeletal changes, glaucoma and focal segmental glomerulosclerosis.

266 possible mechanisms underlying the different focal seizure onset patterns in the model.

267 ental impairment, as well as generalized and focal seizures and EEG abnormalities for patients with g

268 Focal seizures are assumed to arise from a hypersynchron

269 Focal seizures are episodes of pathological brain activi

270 The onset of focal seizures in humans and in different animal models

271 We pharmacologically induced focal seizures in primary visual cortex (V1) of awake mi

272 uliar of the olfactory cortex that resembles focal seizures with low-voltage fast activity at onset o

273 ilepsy, number of seizures before remission, focal seizures, and epileptiform abnormality on EEG befo

274 TERPRETATION: Underlying pathology, repeated focal seizures, and global insults each contribute to at

275 rolling seizures in patients presenting with focal seizures.

276 adequate model using clinical recordings of focal seizures.

277 This approach, based on focal series projections, is easily applicable with clos

278 ho underwent (18)F-FDG PET/CT in search of a focal source of infection was performed.

279 d the difference in time since burning for a focal-source pair ranging from 3 to 58 months.

280 study was to analyze the role of rotors and focal sources in a large academic registry of consecutiv

281 the mechanistic role of biatrial rotors and focal sources in maintaining AF in diverse populations.

282 red for correct identification of rotors and focal sources is a linear function of spatial wavelength

283 A high-contrast focal spot having 487 times higher intensity than the av

284 for the first time that multiple and complex focal spots can be controlled simultaneously at distinct

285 In nondiabetic retina, focal stimulation of a pericyte produced a robust vasomo

286 mon carotid artery occlusion, whereas severe focal stroke injury was induced by Rose Bengal photosens

287 rterial disease process characterized by the focal subendothelial accumulation of apolipoprotein-B-co

288 The reason for such focal susceptibility to cancer remains poorly understood

289 eved in differentiating benign and malignant focal testicular lesions.

290 Finally, we found that focal thalamic lesions in humans have widespread distal

291 ith vincristine, carboplatin, and aggressive focal therapies is an effective regimen for the treatmen

292 white matter changes on T2-weighted imaging, focal tissue loss, and ventriculomegaly were all more co

293 -randomly associated with genetic values for focal traits, animal model parameter estimates can be se

294 location, addition of topotecan, concomitant focal treatment, and time interval between injections we

295 alin and FAK inhibits repulsive turning from focal uncaging of Ca(2+) within filopodia.

296 ring a TGF-beta mAb resulted in a relatively focal uptake in the fibrotic kidney and reduced renal fi

297 Observed focal uptake in the prostate was localized to PSMA-expre

298 eres occupy a volume greater than 18% of the focal volume, the recorded IR spectrum becomes almost in

299 Rel had bilaterally small hippocampi, but no focal white matter atrophy was detected, indicating a li

300 g the accumulation of high-affinity LFA-1 in focal zones of adherent cells.