ライフサイエンスコーパス: focal seizure

1 us network inhibition in the initiation of a focal seizure.

2 h of excitation contributes to terminating a focal seizure.

3 adequate model using clinical recordings of focal seizures.

4 E, suggesting a common lateralized effect of focal seizures.

5 ported focal seizures; (iii) locally induced focal seizures.

6 n of caged GABA to quickly terminate intense focal seizures.

7 increases of brain excitability resulting in focal seizures.

8 al resection for alleviation of uncontrolled focal seizures.

9 cemia may be associated with exacerbation of focal seizures.

10 rolling seizures in patients presenting with focal seizures.

11 Procedures were generally well tolerated; focal seizures (9.2%) were the most frequent side effect

12 The onset patterns of focal seizure activity have been studied intensively, an

13 n postoperative day 5, 7 or 14 had recurrent focal seizures after a latent period of 4-13 days, and s

14 ental impairment, as well as generalized and focal seizures and EEG abnormalities for patients with g

15 Interictal spikes in models of focal seizures and epilepsies are sustained by the synch

16 ing all these into account, benign childhood focal seizures and related epileptic syndromes would nee

17 ilepsy, number of seizures before remission, focal seizures, and epileptiform abnormality on EEG befo

18 TERPRETATION: Underlying pathology, repeated focal seizures, and global insults each contribute to at

19 syndrome, epilepsy of infancy with migrating focal seizures, and intellectual disability or autism wi

20 Focal seizures appear to start abruptly and unpredictabl

21 es, lends weight to the hypothesis that even focal seizures are a network phenomenon that involve wid

22 Focal seizures are assumed to arise from a hypersynchron

23 Focal seizures are episodes of pathological brain activi

24 ible clinical phenotypes of benign childhood focal seizures are likely to be linked together by a gen

25 Our findings support the concept that focal seizures are terminated by the simultaneous and op

26 Now there are new means to induce focal seizures, as with magnetic seizure therapy (MST),

27 Intractable focal seizures began in early childhood, after which lan

28 ion of individuals with medically refractory focal seizures being considered for surgical treatment.

29 endent cell death pathways has been shown in focal seizures, but whether this occurs in prolonged gen

30 and ictal haemodynamic changes in refractory focal seizures can non-invasively localize seizure onset

31 Fifty-five patients with >/=2 refractory focal seizures/day, and who had undergone long-term vide

32 implanted cerebellar electrodes demonstrated focal seizure discharges in the region of the mass.

33 syndrome, epilepsy of infancy with migrating focal seizures (EIMFS).

34 NFLE) and epilepsy of infancy with migrating focal seizures (EIMFS).

35 Systemic administration of CNO suppresses focal seizures evoked by two different chemoconvulsants,

36 to the human condition, chronic spontaneous focal seizures follow a single episode of traumatic brai

37 e supports a role of interneuron activity in focal seizure generation.SIGNIFICANCE STATEMENT The pape

38 , who had epilepsy of infancy with migrating focal seizures, had 80% reduction in seizure frequency a

39 hese three classes are: (i) globally induced focal seizures; (ii) globally supported focal seizures;

40 uced focal seizures; (ii) globally supported focal seizures; (iii) locally induced focal seizures.

41 ses of dynamical mechanisms for the onset of focal seizures in a unified framework.

42 The onset of focal seizures in humans and in different animal models

43 We pharmacologically induced focal seizures in primary visual cortex (V1) of awake mi

44 Focal seizures in rats were induced by neocortical injec

45 lopathy with poor prognosis, presenting with focal seizures in the first year of life.

46 imol can prevent acetylcholine (Ach)-induced focal seizures in the rat neocortex without causing cess

47 to the neural activation threshold and more focal seizure induction, which could potentially reduce

48 diverse insight into the mechanisms of human focal seizure initiation and propagation.

49 known as epilepsy of infancy with migrating focal seizures, is a rare early infantile epileptic ence

50 We conclude that although focal seizures might have different patient-specific aet

51 possible mechanisms underlying the different focal seizure onset patterns in the model.

52 odes implanted in the hamartoma demonstrated focal seizure origin from the hamartoma in 1 patient.

53 million people with drug-resistant epilepsy, focal seizures originating in dysfunctional brain networ

54 diac arrhythmias in patients with refractory focal seizures over an extended period.

55 We describe here a novel, region-specific focal seizure pattern that mimics seizure activity obser

56 1 or CASPR2 antibodies that include frequent focal seizures, prominent amnesia, dysautonomia, neuromy

57 ed in our in vitro experiments, but also for focal seizures recorded in different syndromes, brain re

58 al toward seizure end was confirmed in human focal seizures recorded with intracerebral electrodes in

59 wn if this in vivo gene transfer could alter focal seizure sensitivity in the inferior colliculus.

60 de, however, the promoter determined whether focal seizure sensitivity was significantly attenuated o

61 nin peptide significantly attenuated in vivo focal seizure sensitivity, even with different promoters

62 seizure "generalization" stages (3-6) from "focal" seizure stages (1-2).

63 ed with febrile and multiple afebrile, often focal seizure types, multifocal epileptiform discharges

64 Specifically, we find that although all focal seizures typically appear to arise from localised

65 The effect of focal seizures was inferred from lateralized atrophy com

66 lepsy surgery is indicated for patients with focal seizures who do not respond to appropriate antiepi

67 uliar of the olfactory cortex that resembles focal seizures with low-voltage fast activity at onset o

68 In the UK, driving is not permitted if focal seizures with no impairment of awareness (auras, s

69 pilepsy syndrome clinically characterized by focal seizures with prominent auditory symptoms.

70 Focal seizures with secondary generalization are traditi

71 Among the cohort as a whole, focal seizures, with or without progression to bilateral