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1 FUS is sufficient to retain ASOs in cellular foci.
2 tion, and the protein colocalized with 53BP1 foci.
3 e both primary tumors and distant metastatic foci.
4 ther be useful to detect larger transmission foci.
5 de novo assembly and disassembly of HSP gene foci.
6 as followed by the appearance of transformed foci.
7 led that SHP2 was absent within fibroblastic foci.
8 membrane compartments as well as in nuclear foci.
9 ; papillary projections and solid, echogenic foci.
10 on, suggesting the presence of intramural VA foci.
11 hemicals, the Rad52 protein localized to DRS foci.
12 d surveillance of all potential transmission foci.
13 tenance methylation machinery to replication foci.
14 PET scan, and 49% had (18)F-FDG PET-positive foci.
15 tion of histone 2AX and the formation of RPA foci.
16 ation of caspase 3, and reduction of nuclear foci.
17 A damage spots, forming distinct UVR-induced foci.
18 malaria control discussions of transmission foci.
19 plasma cells that reside in extrafollicular foci.
20 s via ASC(CARD) mediates the assembly of ASC foci.
21 3 was observed in human hyperplastic colonic foci.
22 nlinked, coalesce into discrete intranuclear foci.
23 was predominantly localized to fibroblastic foci.
24 peckle protein NonO to form residual nuclear foci.
25 dominant players and have been the research foci.
26 ve into and then out of adjacent replication foci.
27 A, where it formed enlarged paraspeckle-like foci.
28 associated with development of preneoplastic foci.
29 se and increased formation of new metastatic foci.
30 sis of viral DNA within discrete cytoplasmic foci.
31 er of mutagen-induced aberrant colonic crypt foci.
32 comet assays and quantification of gammaH2AX foci.
33 companied by intense labeling of cytoplasmic foci.
34 es the senescence-associated heterochromatic foci.
35 ion very likely correspond with fibroblastic foci.
36 nduction, RAD51 colocalizes with BRCA2-BCCIP foci.
37 ons in the number of independent Ca(2+) wave foci.
38 foreign circRNA co-aggregate in cytoplasmic foci.
39 AtBRCA1, which can also co-localise with RBR foci.
40 equestration of p65 at the RNA-polymerase-II foci.
42 DNA crosslinking agents, gammaH2AX and 53BP1 foci accumulation, and enhanced p53/p21 activation relat
43 he number of aberrant crypts, aberrant crypt foci (ACF) and crypts/focus in rats of the KJT + AOM gro
44 ed the colonic microbiota and aberrant crypt foci (ACF) in C57BL/6N female mice fed various dietary i
46 human epithelial cells to propose that these foci act as mRNA storage depots rather than mRNA decay f
47 ly, PfSET7 localizes to distinct cytoplasmic foci adjacent to the nucleus in erythrocytic and liver s
48 clusters represents the origins of fibrotic foci after WTI and is promoted by a cross-talk between H
49 ermining the number of p53 binding protein 1 foci, after incubating SSTR2-positive cells with (177)Lu
50 controls, functional pathways involving four foci along the striatal axis were assessed to test the h
51 ures of disease including elimination of RNA foci among all conditions studied (DM1, DM2, C9-ALS, pol
53 The enrichment of S-phase histone gamma-H2AX foci and a striking loss of telomeric DNA in mus81 send1
54 e localized to contracting edges and rosette foci and act to specify edge contraction during rosette
56 ed with reduced telomere-dysfunction-induced foci and anaphase bridges, indicating improved telomere
57 used to infer the localisation of epileptic foci and assist in the design of intracranial EEG record
58 early S aureus killing, sterilising infected foci and blood faster, and reducing risks of disseminati
59 tryptophan uptake and trapping in epileptic foci and brain tumors, but the short half-life of (11)C
60 over, RECQ5-deficient cells accumulate RAD18 foci and BRCA1-dependent RAD51 foci that are both formed
63 elerated DNA repair as revealed by gammaH2AX foci and comet assays and to the up-regulation of Ku70 a
65 h transcription complexes in DNA replication foci and counteracts replication fork stalling in RNAPI-
67 C9ORF72 produced sustained reductions in RNA foci and dipeptide-repeat proteins, and ameliorated beha
68 results in increased spontaneous DNA damage foci and elevated levels of H2AK15ub and impairs DNA dam
70 ce of NMY-2 filaments into large contractile foci and for long-range coordinated contractility in the
73 er, these same mutant alleles disrupted hp53 foci and inhibited biosensor activity, suggesting that t
76 ing formation of telomere-induced DNA damage foci and loss or duplication of telomeric sequences.
79 mized detection of poles, septa, fluorescent foci and organelles, determines their subcellular locali
80 ty, generating a pulsatory pattern of myosin foci and preventing the collapse of cortical material in
81 are characterized by the accumulation of RNA foci and RAN proteins, raising the possibility of a mech
82 to relate to a decreased decay of gamma-H2AX foci and reduced induction of DNA double-strand break re
83 ctors (P < 0.001-0.03) were: hyperreflective foci and retinal pigment epithelium (RPE) layer atrophy
85 decreased correlation of the heterochromatin foci and telomere trajectories in constrained and isotro
86 cence microscopy to count the number of Mcp5 foci and the number of Mcp5 molecules in an individual f
87 accompanied by accumulation of UGGAAexp RNA foci and translation of repeat-associated pentapeptide r
88 berrations, long-lasting gammaH2AX and 53BP1 foci, and augmented cell death upon oxidative telomeric
91 SopE triggered MYO6 localization to invasion foci, and SopE-mediated activation of PAK recruited MYO6
92 1 recruitment to BRCA2-containing DNA repair foci, and that downregulation of cyclin D1 leads to inef
93 ed the ability of HR proteins to form repair foci, and yet both E6 and E7 reduce the ability of the H
99 Intraretinal and subretinal hyperreflective foci as seen on SD OCT correlated to RPE cells on histol
100 ion of senescence-associated heterochromatin foci as well as an increase in mRNA and protein levels o
105 ion and retention of PMO within inflammatory foci associated with dystrophic lesions, and second, fus
108 transient aggregations of RNAs into discrete foci at or near the nuclear membrane triggered by multip
109 xpression assays, and associated at discreet foci at the shank membrane of Arabidopsis pollen tubes.
110 categorized aggressiveness of individual PC foci based on DNA methylation patterns in primary PC foc
111 normal-looking cells surrounding transformed foci became increasingly permissive for transformation w
112 tracardiac echocardiography, with arrhythmia foci being mapped at either the anterolateral papillary
113 he level of BRCA1 recruitment into gammaH2AX foci, being the lowest in cells with missense variants.
114 of WRN is dispensable for relocalization in foci but is involved in the interaction with the MRE11 c
122 ic utility in prostate cancer for gamma-H2AX foci decay ratios and gene expression profiles derived f
123 epleted cells exhibited decreased gamma-H2AX foci, decreased phosphorylation of ATR, and higher level
125 ival surgical resection tissue contained RNA foci, dipeptide repeat protein inclusions, and loss of n
126 ial foci, not a polygonal grouping, simple 2-foci division of attention or a circular spotlight.
127 ssed by immunofluorescence analysis of 53BP1 foci; DSB levels were determined by neutral comet assay;
128 tumors were generally induced from multiple foci due to incomplete Cre-loxP recombination, thus mimi
131 nate phosphoinositide production at invasion foci, facilitating the recruitment of cytoskeleton adapt
132 nd nodal (n = 8) lesions and corresponded to foci FDG uptake, with mean SUVmax of 9.8, 6.7, and 16.2,
133 PI(3,4,5)P3 is then synthesized at the entry foci, followed by the accumulation of PI(3)P on the shor
135 re a total of 330 participants, equaling 132 foci for an activation likelihood estimation (ALE) analy
137 s allowed us to determine spatial expression foci for each expressed gene in the globular embryo, whi
139 erness areas of East and Southern Africa are foci for Rhodesian sleeping sickness, a fatal zoonotic d
142 peats, but the molecular mechanism governing foci formation above this characteristic threshold remai
143 a mutation in RNF113A, are defective in ASCC foci formation and are hypersensitive to alkylating agen
146 ders are pathologically characterized by RNA foci formation and repeat-associated non-AUG (RAN) trans
147 uption of BTB dimerization abrogates nuclear foci formation and telomeric localization of not only SL
148 The monitoring of DNA damage by gamma-H2AX foci formation in human PBMCs (lymphocytes) and acute ly
152 in assembly, immune synapse formation, actin foci formation, mechanotransduction, T cell transendothe
156 d by measuring the loss of GFP-labeled Sup35 foci from both strong and weak [PSI(+)] variants; the fo
157 foveal DRIL (>500 mum DRIL) hyperreflective foci (HRF), average and largest area of intraretinal (IR
158 ty, quantity and location of hyperreflective foci (HRF), vitreomacular interface abnormalities, and e
159 c-Fos-expressing livers display necrotic foci, immune cell infiltration, and altered hepatocyte m
165 y counterpart, hp53 formed prominent nuclear foci in germline cells but cancer-associated p53 variant
171 bers of chromosome aberrations and gammaH2AX foci in non-transformed MCF10A human mammary epithelial
172 found different distributions of LET-23 EGFR foci in rab-7 versus dhc-1 mutants, suggesting that dyne
173 leads to accumulation of gammaH2AX-positive foci in response to DNA damage, which is reversed by nuc
174 iasis (HAT) are confined to spatially stable foci in Sub-Saharan Africa while tsetse distribution is
178 GLKD leads to the accumulation of gamma-H2Av foci in the germ line, indicating increased DNA damage i
179 centrations and development of preneoplastic foci in the liver (increased placental glutathione S-tra
180 alveolar and bronchiolar spaces, and hypoxic foci in the lung (endothelial cells) and brain (neurons
181 tcp10 leaf, which persisted in small defined foci in the margins when the mitotic activity had alread
183 enhances the recruitment of 53BP1 to nuclear foci in the S phase, resulting in impaired HR and the ac
185 regulation results in increased inflammatory foci in tumors and incidence of intracystic adenocarcino
186 cells displayed elevated frequency of Rad52 foci, inactivation of RNase H2 and RAD52 led to syntheti
187 Ser139) histone H2AX (gamma-H2AX) levels and foci indicating increased conversion of stalled replicat
189 The presence of slr1-6SA-GFP hyphal tip foci is reduced in the absence of the mRNA-transport pro
190 itment from flowing blood to atherosclerotic foci is the key first step in the development of atheros
191 the higher-order foci to a pair of conjugate foci, is an attractive alternative to the conventional F
192 ase (DMPK) transcripts accumulate in nuclear foci, leading to abnormal regulation of RNA processing.
193 er-depleted telomeres form RPA and gammaH2AX foci, like the human telomeres lacking the ssDNA-binding
194 the pattern of intraretinal hyperreflective foci migration were documented using spectral-domain opt
196 cted by a representation of discrete spatial foci, not a polygonal grouping, simple 2-foci division o
197 compared to radiography, in detecting lytic foci obscured by other structures or with a small degree
198 wave reflection at tissue edges or multiple foci observed at different locations in neural tissue.
200 igation, we found that spontaneous gammaH2AX foci occurred in DNA-PKcs(3A/3A) skin biopsies and prima
201 ut the focusing dynamics and location of the foci of Abeta peptides and other compounds was obtained
202 table only using IFM and was associated with foci of cardiomyocyte hydropic degeneration and immune c
203 YP11B2-expressing area and areas of abnormal foci of CYP11B2-expressing cells, called aldosterone-pro
205 rge density of the inner leaflet, generating foci of enhanced charge and curvature where endophilin a
208 e tubular lumina of the epididymides, and in foci of histiocytic inflammation in the brain, but not i
209 he possibility remains that other geographic foci of human infection exist, identification of which m
211 lusion:(18)F-FDG PET/CT correctly identified foci of increased uptake compatible with infection in mo
212 embranes from mid-gestation placentas formed foci of infection, and interferon-beta production was pr
215 y-five patients (85%) demonstrated 1 or more foci of intramucosal signet ring cell gastric cancer in
216 pancreatic intraepithelial lesions and more foci of invasive cancer than pancreata of unexposed mice
217 he location of a single focus or of multiple foci of involvement and the presence of drainable collec
218 dings suggest that multiple highly connected foci of measles transmission coexist in China and that m
219 ncreasing in incidence with newly recognized foci of melioidosis in the Americas, Africa, and elsewhe
220 also suggest that the CR may be derived from foci of myosin II filaments in a manner similar to what
221 iant H2AX, and a low-density core containing foci of phosphorylated H2AX (a marker of double-strand b
225 ed in future prospective studies as distinct foci of research on individual differences in vulnerabil
226 e developed methodology to identify discrete foci of SIV (mac239) infection 48 hr after vaginal inocu
227 membrane proteins and phospholipids were the foci of study, thus providing a jumping-off point for ad
231 polarization at intraretinal hyperreflective foci on PS-SLO and PS-OCT images, and by the presence of
234 ies and primary keratinocytes and that these foci overlapped with telomeres during mitosis, indicatin
235 oci per cell +/- 0.02; 5 minutes after: 0.12 foci per cell +/- 0.02; 30 minutes after: 0.11 foci per
236 ned with MR imaging (before MR imaging: 0.13 foci per cell +/- 0.02; 5 minutes after: 0.12 foci per c
238 d after CT exposure (before MR imaging: 0.14 foci per cell +/- 0.05; 5 minutes after: 0.26 foci per c
239 oci per cell +/- 0.05; 5 minutes after: 0.26 foci per cell +/- 0.07; 30 minutes after: 0.24 foci per
240 ci per cell +/- 0.07; 30 minutes after: 0.24 foci per cell +/- 0.07; P </= .05), no alterations were
245 known to sequester metal ions at infectious foci) recapitulates responses occurring within metal-dep
247 MeCP2 protein is enriched in heterochromatic foci, reflecting restoration of normal MeCP2 binding to
248 ion showed that intraretinal hyperreflective foci represent cells of retinal pigment epithelium origi
249 virus led to reductions in pathological RNA foci, rescue of chloride channel 1 protein expression, a
250 The average number of radiation-induced foci (RIF) per cell increased over the first 3 h after r
251 ins of senescence-associated heterochromatin foci (SAHF), as well as specific families of non-genic a
254 urses sampled from independently defined DMN foci showed significant shift selectivity during the dem
256 tor complex) relocalizes to distinct nuclear foci specifically upon exposure of cells to alkylating a
257 egion also prevented formation of subnuclear foci, structures potentially important for epigenetic re
259 y provoke the formation of single gamma-H2AX foci, suggesting similar activation of early DNA damage
260 and higher levels of residual 53BP1 and RIF1 foci, suggesting that DNA double-strand break (DSB) repa
261 of CT was found in detecting cases of small foci suspicious of lytic lesions on skull radiographs, s
264 umulate RAD18 foci and BRCA1-dependent RAD51 foci that are both formed at sites of interference betwe
265 und that WNK bodies are dynamic membraneless foci that are distinct from conventional organelles, col
267 liquid demixing in vitro, and nucleates into foci that display liquid properties during the first sta
268 yeast's 32 telomeres are clustered into 6-10 foci that dynamically interact with the nuclear membrane
269 clusters and colocalize in distinct nuclear foci that overlap with sites of piRNA transcription.
270 t cells formed ectopic centrosomal-component foci that suppressed mitotic defects associated with cen
271 ker of senescence-associated heterochromatic foci that synergizes with DNA methylation to silence tum
273 ins at ionizing radiation-induced DNA damage foci that Wwox expression suppresses DSB repair at the e
274 TM activation and ionizing radiation-induced foci, they display apoptotic pannuclear H2AX-S139 phosph
275 ruitment of BRCA tumor suppressors to damage foci through binding of both ubiquitin (Ub) and the Ub-l
276 one plate, which suppresses the higher-order foci to a pair of conjugate foci, is an attractive alter
277 e deficits included the failure of bacterial foci to attract macrophages and NK cells, cell types kno
279 g cofactor that is activated at inflammatory foci to enhance lymphocyte chemotaxis represents a power
280 of phospho-SER139-H2AX (gammaH2AX) and 53BP1 foci, two factors involved in the DNA damage response ne
283 e appearance of intraretinal hyperreflective foci was preceded by thickening of the RPE-basal lamina
285 To induce formation of pancreatic tumor foci, we electroporated oncogenic plasmids into pancreat
289 expressing human ENPP1, small mineralization foci were still evident despite increased plasma PPi lev
290 's basal medium (DME) produce no transformed foci when grown to confluence in 10% calf serum (CS).
291 MO localization is sustained in inflammatory foci where it enters macrophages, actively differentiati
292 x has a tendency to form a pattern of myosin foci, which is a signature of potentially unstable behav
293 N) complex were found in distinct E2 nuclear foci, which peaked during mid-S phase, indicating that t
294 complexes to concentrate into large discrete foci, which we call "WNK bodies." Although these structu
295 pear to be spatially organized into distinct foci, which we have previously termed mitochondrial RNA
298 lity of tumour cells to establish metastatic foci, with 19 of these genes not previously demonstrated
299 dicating that the recruitment of Rint1 to E2 foci within the nucleus may also result in the recruitme
300 in minimal serum, they produced transformed foci without transfection in 10% CS, but not in 2% CS.
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