ライフサイエンスコーパス: focus on

1 We focus on: (1) attempts to formulate design principles to

2 For further analysis, we focus on 12 therapeutically relevant genes and consider

3 l curation of 23 489 individual publications focused on 186 key genes and 286 key fusion pairs across

4 Being able to focus on a complex task and inhibit unwanted actions or

5 Here, we focus on a imidazolium based IL and use particle-probe r

6 et most research and regulation continues to focus on a limited selection of rather well-known long-c

7 inspire scientists' interests in starting to focus on a new pathway instead of making huge effort or

8 The method focused on a putative binding site in GPR39 for syntheti

9 In this novel study, we focused on a relationship between endoplasmic reticulum

10 iversity protection, most insights are still focused on a single facet of biodiversity-species.

11 This research focuses on a novel method of ARD treatment, membrane dis

12 onsequently, recent research in drylands has focused on abiotic mechanisms, mainly photochemical and

13 Future intervention should focus on adjustable correlates such as behavioural and p

14 T imaging and therapeutic approaches, with a focus on agents that have been clinically adopted.

15 This review focuses on alterations in hematopoietic TFs in the patho

16 This review focuses on AMPD-based self-assembled nanoparticles, from

17 Our studies focus on an important agronomic trait in a major crop fo

18 Of those, we chose to focus on an inhibitor of heat shock protein 90 beta (HSP

19 Instead of focusing on an individual patient, genetic testing requi

20 Although current methods have mostly focused on analyzing bacteria whose genomes have been se

21 The immune system focuses on and responds to very few representative immun

22 Many studies of ecoevolutionary change have focused on anthropogenic drivers, but none of these stud

23 Also, most studies focused on attenuation of heat-related mortality and stu

24 e studied in many disciplines, with a recent focus on average avalanche shapes, i.e., the temporal pr

25 s, the argument is made that decision-makers focus on avoiding permit violations and negative publici

26 Future studies should focus on better defining the role of MAC and facility an

27 Our analyses focused on BH3 mimetics that are broad acting (ABT263 an

28 Most studies have focused on biomarker discovery rather than exosome funct

29 ernal, neonatal, and child health programmes focused on biomedical determinants might not sufficientl

30 The present review focuses on cardiorespiratory fitness (commonly measured

31 We focused on cases involving a major nosocomial-associated

32 is review, I highlight these advances with a focus on cells and pathways that may be amenable to ther

33 t intracellular immunization strategies that focus on cellular components of viral integrase protein

34 This retrospective cohort study focused on children hospitalized for 3 or more days who

35 ke on mouse hippocampal interneurons largely focusing on cholecystokinin-expressing interneurons (CCK

36 tion of novel single cell analysis platforms focused on circulating tumor cells (CTCs).

37 This Review focuses on classical metal ion modeling based on unpolar

38 Increasing research focus on CND will likely transform our perspectives on h

39 We subsequently focused on COL12 and show that COL12 binds COP1 and SPA

40 uromuscular disorders, and aging of the NMJ, focusing on communications among motoneurons, muscles an

41 Therefore, focusing on community assembly and the functioning of ec

42 This work focuses on comparing two DBD configurations: the low tem

43 n of inhibitors of polyQ amyloid growth that focuses on conformational requirements for fibril and nu

44 e helical conformations are explored, with a focus on contrasting CAG and GAC duplexes.

45 This review will focus on current findings of the involvement of neutroph

46 workshop presentations and panel discussions focused on current understanding and knowledge gaps rela

47 e effects of contact inhibition because they focus on data describing early time, low-density dynamic

48 In light of these challenges, this review focuses on describing examples in which we might begin t

49 nt over the present methods that excessively focus on detecting mechanical deformations and cracks.

50 Future research should focus on developing a working definition of familial PCA

51 This paper focuses on developing a label-free electrochemical biose

52 a clinical overview of atrial fibrillation, focusing on diagnosis, treatment, and practice improveme

53 identifying potent inhibitors of FXIa with a focus on discovering an acute antithrombotic agent for u

54 ns will be more clearly understood through a focus on disease ecology.

55 Prediction to date has focused on disentangling interactions between resource l

56 We focus on Dugesia japonica fission and show that it proce

57 This supplement focuses on efforts by global partners to successfully la

58 the past two decades, multiple studies have focused on elucidating the causative factors underlying

59 For years, DFT development focused on energies, implicitly assuming that functional

60 The MZ difference design allowed us focus on environmental factors that vary within twin pai

61 Here, we focus on Exserohilum rostratum, a dematiaceous mold that

62 Most efforts have been focused on extracting the kinetic energy from the motion

63 submit a novel animal experimental approach focusing on extreme phenotypes.

64 Future work should focus on facilitating induction to XR-NTX and on improvi

65 We focus on fallow deer to better understand the relative i

66 Drosophila innate behaviors, with a special focus on feeding, courtship, aggression, and postmating

67 We focused on females because in both humans and rodents, t

68 llaborations to address optimal prescribing, focusing on five countries that have developed different

69 We focused on FOXP1 and assessed its protein expression by

70 To date, most ErbB4 studies have focused on GABAergic interneurons in the hippocampus and

71 tify driver mutations in cancer have largely focused on genes, whereas non-coding sequences remain re

72 Thus far, few studies has focused on genomic expression related to selective toxic

73 Importantly, studies focused on geographic and cultural differences in intest

74 dinally characterized in the rhesus macaque, focusing on gestation day (G85) through G135 of the 165

75 romosome segregation errors, with a specific focus on Gravin, a PLK1 scaffold.

76 Significant interest in recent years has focused on gut microbiota-host interaction because accum

77 ic mechanisms involved in alcohol abuse have focus on hepatic and neuronal regions, leaving the immun

78 s in cancer cell metabolism, with an initial focus on HIF-mediated effects, and will highlight how th

79 ticulate ambient air pollution exposure have focused on high-income countries, which have much lower

80 of available pacing options, with particular focus on His-bundle pacing.

81 In this review, we focus on how intracellular bacterial pathogens target in

82 Future efforts should focus on how to exploit this knowledge to effectively co

83 While most eQTL studies focus on identifying mean effects on gene expression usi

84 ced genomes belonging to this family, with a focus on identifying proteins enriched in phytopathogens

85 SMA therapeutics development efforts have focused on identifying strategies to increase SMN expres

86 The work focuses on implementing complementary solution-phase foo

87 In this work, we focus on improving identification of textual uncertainty

88 assembly algorithms and for the researchers focused on improving draft assemblies of specific organi

89 While previous work has largely focused on in vitro cellular models, here we demonstrate

90 patially patchy resources, with most studies focusing on indirect evidences, ultimately affecting our

91 zed cohort of 5-year CCSs, with a particular focus on individual chemotherapeutic agents and solid ca

92 ultimodel comparisons with data have largely focused on individual processes at subannual to decadal

93 The study of decision-making has mainly focused on isolated decisions where choices are associat

94 ons into the function of CLEC-2 in vivo have focused on knockout (KO) studies in which both the recep

95 kages, one delivered through schools and one focusing on later adolescence, would provide phase-speci

96 Classical Swine Fever (CSF) should not only focus on livestock, but must also include wild boar.

97 tempts to culture these primary cancer cells focus on long-term maintenance under growth factor suppl

98 s susceptibility and resilience studies have focused on males as one commonly used paradigm-chronic s

99 We observed a significant focus on mammalian hosts, a few well-studied or purely t

100 Society increasingly focuses on managing nature for the services it provides

101 (stable, extractable, separable, detectable) focusing on marker compounds do not cover all relevant i

102 Most research into underuse has focused on measuring solutions to the problem, with cons

103 Future studies that focus on mechanisms, resiliency, and vulnerability facto

104 quantification approaches in lung diseases, focusing on methods to account for variations in lung co

105 Here, we focus on methyl-CpG binding protein 2 (MECP2) restoratio

106 , we discuss the potential of biotechnology, focusing on microbes with a natural ability to utilize a

107 Most of studies have focused on molecular and pathogenic characterization of

108 RA currently focuses on monomers and additives used in the manufactur

109 ively reviewed for many viruses, this review focuses on MT filaments themselves.

110 y scattered light-to reveal GCs has led to a focus on multiply-scattered, fluorescence, two-photon, a

111 We focus on mutant U2AF1 and utilize sudemycin compounds th

112 We focused on N400 time window and results showed that inco

113 is of complex quantum devices with a special focus on nanowire networks with a predefined number of s

114 Assessments largely focused on national bans of specific pesticides (12 stud

115 We focus on new methods for physics-based, knowledge-based,

116 We focused on nine genes (AOX1, CCDC181 (C1orf114), GABRE,

117 In this manuscript, we have focused on OleTJE active site residues Phe(79), His(85),

118 This study focuses on oncolytic vesicular stomatitis virus (VSV) ag

119 of the 3'UTR of targeted transcripts, and we focus on one cell type (monocytes) and on a small set of

120 The second part focuses on one of the most distinctive, but elusive, fea

121 te of knowledge of the NVU will be assessed, focusing on one of its most vital roles: the coupling be

122 Online process monitoring with a focus on optical spectroscopy can provide a fast, nondes

123 Future research should focus on optimal probiotic dose, species, and formulatio

124 tion to other common food allergens and that focus on optimal timing, duration, and adherence are req

125 ng System could identify patients wishing to focus on palliative care measures.

126 o achieve these goals, many researchers have focused on paper-based and printed electrode technologie

127 Although numerous studies have focused on pentameric ligand-gated ion channels, the det

128 Whereas the majority of studies in the field focus on peptides containing only one or two types of am

129 The present review focuses on peptidomic approaches to the investigation of

130 Increasing efforts have focused on pharmacological hypothermia as a treatment op

131 ized plastics on organisms, whereas few have focused on plastic nanoparticles, despite their distinct

132 We review strategies for case management, focusing on point-of-care tests that hold considerable p

133 Focus on post-treatment cancer care, including monitorin

134 MBL-an open-source literature-based database focused on preclinical drug discovery.

135 Synthetic chemists have focused on preparing such model compounds, as they can b

136 Future interventions might focus on preserving exercise capacity.

137 clinical trials of these treatments, with a focus on preventing congenital central nervous system ma

138 nguage has led several fields of research to focus on primate vocal communication.

139 Focusing on principles that enable new levels of functio

140 Policy and organizational change focused on promoting NP work environments so NPs can pra

141 Here we focused on prophages, the least characterized mobile ele

142 Many of these studies focus on rare event categorical data, and functional gen

143 This study focuses on ReaChR, a chimeric ChR variant with optimal p

144 nsensus cognitive battery (MCCB), especially focusing on reasoning and problem solving, and social co

145 Here, we focus on recent findings and propose directions for futu

146 by heme proteins and model compounds with a focus on recent progress in the characterization and rea

147 This review focuses on recent advances in the neurosciences that con

148 This review focuses on recent human (18)F-FDG PET studies in Parkins

149 This review focuses on recent insights into the evolution of the tra

150 This review starts with human SRA and mainly focuses on recent progress on the roles of NFIC-dependen

151 prehensive overview of prostate development, focusing on recent findings regarding sexual dimorphism,

152 , we summarize recent progress in the field, focusing on recent studies that have characterized the c

153 eview and update on the prevention of FA and focuses on recently published randomized controlled tria

154 TLD have been advanced, with recent efforts focused on recombination proteins and replication origin

155 Studies of HIV-1 latency have focused on regulation of viral gene expression in cells

156 A second team focused on replicating the key claim of an interaction b

157 metry and loading, current therapy is mainly focused on resting conditions.

158 A focus on reversible mechanisms identified Insulin-like g

159 We focus on roles for CARMILs in signaling in addition to t

160 ly on seed production; although useful, this focus on seed set does not provide information regarding

161 on the future (vs. present), and a stronger focus on self-control.

162 ion of serotype-specific regulator mutations focuses on serotype M3 GAS isolates, and how the identif

163 These studies focused on short-term change, using a 2-stage process, t

164 s dynamic, microbiome studies have primarily focused on single time points or a few individuals.

165 nges, including short-term surveillance that focuses on single epidemics and acutely ill individuals,

166 This review focuses on single nanoparticle detection using optical w

167 Focusing on single column formation, we show that this s

168 arse resolutions, while community ecologists focus on small extents and fine resolutions.

169 Current synteny visualization tools either focus on small regions of sequence and do not illustrate

170 owever, most studies of link prediction have focused on social networks, and have assumed a completel

171 Extensive prior research focused on somatic copy-number alterations (SCNAs) affec

172 We focused on somatostatin-positive (SST(+)) GABAergic inte

173 This review focuses on some of these lysosomal enzymes and transport

174 have considered soil biota as a black box or focussed on specific groups, whereas little is known abo

175 as well as hospital-specific mentoring which focused on strengthening leadership, increasing the volu

176 The candidates are first identified by focusing on structures with methane-inaccessible pores b

177 ring action stopping and action preparation, focusing on studies that have used TMS to monitor change

178 obal coral bleaching event has sharpened the focus on such interventionist approaches.

179 of the mechanism for AD and is particularly focused on suppressing the skewed immune activation.

180 evated BMI highlights the need for continued focus on surveillance of BMI and identification, impleme

181 ti-cancer drug development efforts have been focused on targeting it, most notably by inhibiting its

182 drought measures and, as a global study that focuses on temperate drylands, highlight a distinct fate

183 Recent focus on temperature as a determinant of microrefugia in

184 efforts in the Red Deer region will need to focus on the >90% of methane emissions currently unmeasu

185 nal view of the Bam35 viral proteome, with a focus on the composition and organization of the viral p

186 Here, we focus on the conserved sex-determination gene doublesex

187 ected myeloid and lymphoid neoplasms, with a focus on the current and future role of HTS-based assays

188 This review will focus on the current CE-mark approved bioresorbable scaf

189 This review will focus on the current knowledge for the main subclasses o

190 We approach SRM from another direction: we focus on the current practical limitations and compromis

191 gress in chemical genetics in plants, with a focus on the discoveries regarding small molecules ident

192 Here we focus on the estimation of visual speed, a critical sour

193 We have put a particular focus on the evaluation of the degree of addition and th

194 This review will focus on the evidence for genetic causes underlying CHD

195 concepts in the care of MPM patients with a focus on the expanding role of MMT in MPM.

196 We focus on the formation of hindbrain segments (rhombomere

197 pt a slower life history strategy, a greater focus on the future (vs. present), and a stronger focus

198 We focus on the hippocampus neuronal cell death, as well as

199 Here, we review these studies with a focus on the immunophenotype, biological properties, epi

200 is warranted, and as such, this review will focus on the incidence, surveillance, and treatment of u

201 yed from a drug discovery perspective with a focus on the key advances in knowledge which have led to

202 d by the concept of hydrogen bond, herein we focus on the Li bond chemistry in Li-S batteries through

203 s to measure the depth of impoverishment but focus on the median depth for the 122 countries in our s

204 otential GPR143 interaction partners, with a focus on the melanogenic enzyme tyrosinase.

205 of nucleases acting at stalled forks with a focus on the nucleolytic degradation of nascent DNA, a p

206 Here, we focus on the process of cellularization in the anterior

207 We study elastic gridshells with a focus on the rational design of the final shapes.

208 In this paper we focus on the removal of fecal indicator bacteria (FIB, a

209 There has been increasing focus on the rising burden of atrial fibrillation (AF) s

210 Ps during the methanogenic step of AD with a focus on the role of acetate kinase (AK), which is a key

211 This review will focus on the role of cell death in maintenance of T-cell

212 In this review, we focus on the role of eCB signaling on the regulation of

213 Future investigations should focus on the role of Pax3+ cells in the diaphragm during

214 Whereas another review will focus on the role of Runx factors in leukemias, this rev

215 We focus on the search duration and the statistics of the t

216 We focus on the spiking statistics of the central node, whi

217 Many methods focus on the structural or molecular properties of plaqu

218 The study of brain plasticity has tended to focus on the synapse, where well-described activity-depe

219 erlying the emergence of electromotility, we focused on the betaV giant spectrin, a major component o

220 In particular, their work focused on the biases that can arise in ABMs that use pa

221 Many studies have focused on the biological response of terrestrial taxa a

222 To date, many reviews have been focused on the biomedical properties and applications of

223 In this study, we focused on the contribution of acquired MHC-class I on r

224 eering strategies to enhance TAG levels have focused on the conversion of DAG to TAG.

225 Current 2D bioelectronics research is focused on the design of simple-to-use and cheaper biode

226 However, this literature has largely focused on the effects of current family circumstances.

227 We focused on the expression profiles of the key genes rela

228 Particular efforts have focused on the formation of the ventral furrow, whereby

229 In this work, we focused on the fundamental insights responsible for the

230 d ultrahigh throughput droplet microfluidics focused on the generation of hundreds of thousands or ev

231 We specifically focused on the GluN2B NMDAR subunit, which is highly exp

232 Research to date has focused on the hypothesis that an underlying genetic sus

233 Although research has focused on the identification of genetic abnormalities,

234 Instead, work has focused on the implementation and validation of the ther

235 r the ppDIO-induced alterations in sleep, we focused on the lateral hypothalamus (LH).

236 In the current behavioural and EEG study, we focused on the lateral prefrontal cortex including dorsa

237 While previous studies have been focused on the molecular details of the bud site selecti

238 The field of immunology is principally focused on the molecular mechanisms by which hematopoiet

239 ildhood malignancies, while few studies have focused on the offspring's risk of adult cancer.

240 blished in English between 2010 and 2016 and focused on the relationship between the Practice Environ

241 nitiative for severe sepsis and septic shock focused on the resuscitation bundle on 90-day mortality.

242 In this study, we focused on the role of T cells in the maintenance/surviv

243 d antigenicity-guided mutagenesis strategies focused on the V2 and V3 regions and the gp120-gp41 inte

244 We focused on the variations in crown height, dental erupti

245 We focused on the ventral striatum (VS), due to its associa

246 This review focuses on the applications of SIRM to cancer metabolism

247 This review focuses on the biogenesis and composition of the eukaryo

248 The present work focuses on the development of a fast and cost effective

249 Therefore, our work focuses on the diversity of the DOM and PM types investi

250 This review focuses on the epithelial stem cells of skin, where they

251 This review focuses on the etiology of DNA damage in the nervous sys

252 An accompanying paper focuses on the integrative role of K(+) channels in card

253 ce, one dimension of content validity, which focuses on the match between content in the discipline a

254 Most of the literature focuses on the mesolimbic nuclei as the core of reward b

255 This Series paper focuses on the most relevant clinical questions, summari

256 The present Perspective focuses on the opportunities that silicon incorporation

257 This review focuses on the overall strategies which can improve the

258 This review focuses on the possible applications of bioimprinting wi

259 This review focuses on the recent progress made in H2S signaling tha

260 This review focuses on the relative merits of 3 approaches to molecu

261 A nascent area of research focuses on the utility of epigenetic marks in capturing

262 a resting state and an experimental paradigm focusing on the anticipation of actively touching an ani

263 Furthermore, focusing on the case study, we show the higher biologica

264 and forms a distinct boundary between them, focusing on the conserved cytokinesis midzone proteins P

265 overview of bioprosthetic valve durability, focusing on the definition, incidence, mechanisms, predi

266 ted nickel coatings by brush electroplating, focusing on the electroplating setup and processing para

267 ications, and transcription factor activity, focusing on the ERK-regulated ternary complex factor fam

268 English-language published qualitative study focusing on the experience of men after prostatectomy),

269 ) on the mitigation of GvHD by AzaC, instead focusing on the generation of suppressive Tregs (CD4(+)C

270 autophagy as an anoikis resistance pathway, focusing on the intracellular signals associated with in

271 particle size and shape on the SERS signal, focusing on the most common anisotropic morphologies use

272 By focusing on the neuroendocrine prostate cancer mutationa

273 r adsorption capacities is discussed, mainly focusing on the physical interactions and chemical react

274 island and mainland plant breeding systems, focusing on the presence or absence of self-incompatibil

275 New studies, often focusing on the regulation of chromosomal proteins like

276 Focusing on the RNA editing hotspot in miR-200b, a key t

277 The present study examines this issue by focusing on the role of stromal interaction molecule 1 (

278 model the Neolithic spread in the region by focusing on the role of voyaging to understand better th

279 Focusing on the three lowest-order multipoles-the total

280 Although we have focussed on the Trinity package, we propose that such cl

281 undertake a first step in this direction by focussing on the pressure-driven insulator-metal transit

282 In addition, the intense research focus on these species has spawned an unprecedented dive

283 trials evaluating novel therapies should be focused on these patients.

284 tious Diseases-funded Technical Consultation focused on this organism.

285 Focusing on three UK river catchments with contrasting b

286 engineering are highlighted, with a special focus on tobacco (Nicotiana tabacum).

287 The historical focus on transcription of protein-coding genes has left

288 In this paper, we focus on two common classes of integration algorithms, g

289 new infections annually, and current efforts focus on understanding cellular immunity for targeted va

290 Future studies should focus on understanding the determinants of sex differenc

291 In this study, we focus on understanding the role of seed dispersal by ani

292 es on Mycoplasma pneumoniae in Thailand have focused on urban centers and have not included molecular

293 nsistent with field studies that have mostly focussed on very small populations such as recently intr

294 Here we first focus on visual search and combine object detectors from

295 of risk genes and their implications, with a focus on voltage-gated calcium channels as part of the d

296 Previous studies focused on what happens when the negative feedback domin

297 PRACTALL 2017 is focused on what has been established regarding the role

298 st methods to reduce the control energy have focused on where, in the network, to place additional co

299 ifficult to resolve, with the current debate focusing on whether sponges (phylum Porifera) or comb je

300 s and NAMs of mGluRs in rodents and monkeys, focusing on whether they reduce drug self-administration