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1 pendent on its function as a plasma membrane folate transporter.
2 plex 1 and 2 and requires the proton-coupled folate transporter.
3 n in the PCFT gene encoding a proton-coupled folate transporter.
4 of the recently reported human mitochondrial folate transporter.
5 cells occurs exclusively through the reduced-folate transporter.
6 human folate receptor and the human reduced-folate transporter.
7 ed to validate the functions of the putative folate transporters.
8 n cells that express only the proton-coupled folate transporter and accumulated folates by this mecha
9 orter is most closely related to the reduced-folate transporter and thus represents the second member
10 ane of S180 cells by the one-carbon, reduced folate transporter as well as the KD for binding to the
11 neural retina and uses not only the reduced-folate transporter but also the folate receptor alpha in
12 dentified a tandem array of genes encoding a folate transporter family, TbFT1-3, as major contributor
14 -of-function mutations in the proton-coupled folate transporter gene (pcft/SLC46A1) resulting in impa
16 n organization of the isolated mitochondrial folate transporter gene were deduced from the expressed
18 ecrease in mRNA levels of the proton-coupled folate transporter/heme carrier protein 1 (PCFT/HCP1) an
19 n of the cDNA responsible for the intestinal folate transporter; iii) delineation of intracellular me
20 ork in a coordinated manner with the reduced-folate transporter in the vectorial transport of folate
21 ssion of the folate receptor and the reduced-folate transporter in these cells was evaluated by funct
27 ith the recent cloning of the proton-coupled folate transporter (PCFT) and the demonstration that thi
28 folate carrier (RFC) and the proton-coupled folate transporter (PCFT) are ubiquitously expressed in
29 ivation of Cbs, Mthfr, or the proton-coupled folate transporter (Pcft) gene resulted in a 10- to 30-f
36 olate receptors (FRs) and the proton-coupled folate transporter (PCFT) over the reduced folate carrie
38 ely] into solid tumors by the proton-coupled folate transporter (PCFT) represents a novel therapeutic
39 olate receptor (FR) alpha and proton-coupled folate transporter (PCFT) uptake specificity over the re
40 it was only recently that the proton-coupled folate transporter (PCFT) was identified and its critica
41 reduced folate carrier (RFC), proton-coupled folate transporter (PCFT), and folate receptors (FR) are
42 ate receptor alpha (FRalpha), proton-coupled folate transporter (PCFT), and reduced folate carrier (R
43 ), methionine synthase (MTR), proton-coupled folate transporter (PCFT), and reduced folate carrier (R
44 this laboratory identified a proton-coupled folate transporter (PCFT), with optimal activity at low
50 -of-function mutations in the proton-coupled folate transporter (PCFT, SLC46A1) result in the autosom
54 l role of His residues in the proton-coupled folate transporter (PCFT; SLC46A1), which mediates intes
55 folate carrier (RFC), the major facilitative folate transporter, RFC expression may alter drug effica
57 ntial polarized distribution of the reduced- folate transporter (RFT-1) and folate receptor alpha (FR
59 vidence in these cells for expression of the folate transporter that prefers nonreduced folate as a s
60 ion of a human proton-coupled, high-affinity folate transporter that recapitulates properties of fola
61 s time FRalpha has only been considered as a folate transporter, these studies describe a novel role
63 undance of the heme importer, proton-coupled folate transporter, was related to neonatal SF (beta = 0
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