ライフサイエンスコーパス: foot-and-mouth disease

1 r fear of spreading the much more contagious foot and mouth disease.

2 l predictions in the event of an outbreak of foot-and-mouth disease.

3 or development as effective vaccines against foot-and-mouth disease.

4 an important animal pathogen responsible for foot-and-mouth disease.

5 study up to now of the epidemiology of hand, foot, and mouth disease.

6 1 continues to cause large outbreaks of hand foot and mouth disease across Asia, associated with neur

7 are emerging pathogens associated with hand, foot, and mouth disease and pediatric respiratory diseas

8 ynamics and immunity patterns of local hand, foot, and mouth disease and to optimise interventions.

9 (EV-A71) is the major cause of severe hand, foot, and mouth disease and viral encephalitis in childr

10 ers a potential route of vaccination against foot-and-mouth disease and may be useful for eliciting p

11 -Mouth disease), two datasets of serotype A (Foot-and-Mouth disease) and two datasets of influenza wh

12 y included 7,200,092 probable cases of hand, foot, and mouth disease (annual incidence, 1.2 per 1000

13 ostly affects children, manifesting as hand, foot, and mouth disease, aseptic meningitis, poliomyelit

14 ue-negative samples) from suspected cases of foot-and-mouth disease collected from 65 countries betwe

15 We present an analysis of the current foot-and-mouth disease epidemic in Great Britain over th

16 elopment of the control policies in the 2001 foot-and-mouth disease epidemic in the UK.

17 The foot and mouth disease (FMD) epidemic in British livesto

18 Here we show that, during the outbreak of foot and mouth disease (FMD) in 2001, there was a signif

19 Foot-and-mouth disease (FMD) can cause large disruptive

20 del uncertainty as management proceeds, with foot-and-mouth disease (FMD) culling and measles vaccina

21 Candidate foot-and-mouth disease (FMD) DNA vaccines designed to pr

22 act of such linked holdings on the size of a Foot-and-Mouth Disease (FMD) epidemic.

23 ar ban on fox-hunting during the outbreak of foot-and-mouth disease (FMD) in 2001 to examine this iss

24 ctor expressing IFNs can effectively control foot-and-mouth disease (FMD) in cattle and swine during

25 its potential to control major epidemics of foot-and-mouth disease (FMD) in livestock is contentious

26 In 1997, a devastating outbreak of foot-and-mouth disease (FMD) in Taiwan was caused by a s

27 Foot-and-mouth disease (FMD) in the UK provides an ideal

28 The recent outbreak of foot-and-mouth disease (FMD) in the United Kingdom is a

29 Foot-and-mouth disease (FMD) in Turkey is controlled usi

30 Foot-and-mouth disease (FMD) is a highly contagious vira

31 Foot-and-mouth disease (FMD) is a highly contagious vira

32 Foot-and-mouth disease (FMD) is a worldwide problem limi

33 Foot-and-mouth disease (FMD) is one of the most feared v

34 ly more stable vaccine candidates.IMPORTANCE Foot-and-mouth disease (FMD) is the most devastating dis

35 Foot-and-mouth disease (FMD) remains one of the most dev

36 Production of foot-and-mouth disease (FMD) vaccines requires cytosolic

37 Foot-and-mouth disease (FMD) virus (FMDV) circulates as

38 ised in cattle in response to infection with foot-and-mouth disease (FMD) virus.

39 DNA vaccine candidates for foot-and-mouth disease (FMD) were engineered to produce

40 f bovine spongiform encephalopathy (BSE) and foot-and-mouth disease (FMD), and the advent of new tech

41 h later with FMDV developed typical signs of foot-and-mouth disease (FMD), including fever, vesicular

42 In the case of notifiable diseases, such as foot-and-mouth disease (FMD), these analyses provide imp

43 ent for control and potential eradication of foot-and-mouth disease (FMD).

44 6) are the major etiological agents of hand, foot and mouth disease (HFMD) and are often associated w

45 Hand Foot and Mouth Disease (HFMD) constitutes a considerable

46 To monitor search trends on Hand, Foot and Mouth Disease (HFMD) in Guangdong Province, Chi

47 (EV71) is an emerging pathogen causing hand, foot, and mouth disease (HFMD) and fatal neurological di

48 virus A71 (EV-A71) is a major cause of hand, foot, and mouth disease (HFMD) and is particularly preva

49 viridae family and are major causes of hand, foot, and mouth disease (HFMD) and pediatric respiratory

50 f enterovirus 71 (EV71) and associated hand, foot, and mouth disease (HFMD) are recognized as emergin

51 Epidemiology and etiology of hand, foot, and mouth disease (HFMD) based on large sample siz

52 87% (9.8 million/11.3 million) of all hand, foot, and mouth disease (HFMD) cases reported to WHO dur

53 Hand, foot, and mouth disease (HFMD) has spread throughout the

54 Hand, foot, and mouth disease (HFMD) is a common childhood ill

55 Hand, foot, and mouth disease (HFMD) is a common childhood ill

56 Hand, foot, and mouth disease (HFMD) is a reemerging illness c

57 ily Picornaviridae), a common cause of hand, foot, and mouth disease (HFMD), may also cause severe ne

58 picornavirus that causes outbreaks of hand, foot, and mouth disease (HFMD), primarily in the Asia-Pa

59 us 71 (EV71) causes large outbreaks of hand, foot, and mouth disease (HFMD), with severe neurological

60 Enterovirus 71 (EV71) can cause hand-foot-and-mouth disease (HFMD) in young children.

61 the primary causes of the epidemics of hand-foot-and-mouth disease (HFMD) that affect more than a mi

62 s recently emerged as a major cause of hand, foot and mouth disease in children worldwide but no vacc

63 ccines.Coxsackievirus A6 (CVA6) causes hand, foot and mouth disease in children.

64 , we characterised the epidemiology of hand, foot, and mouth disease in China on the basis of enhance

65 responsible for seasonal outbreaks of hand, foot, and mouth disease in the Asia-Pacific region.

66 Enterovirus 71 (EV71) causes hand, foot, and mouth disease in young children and infants.

67 onses play a major role in the resolution of foot-and-mouth disease in cattle.

68 such as occurred during the 2001 epidemic of foot-and-mouth disease in Great Britain.

69 framework is used to analyse an outbreak of foot-and-mouth disease in the UK, enhancing current unde

70 f poliovirus infection and in the control of foot-and-mouth disease infection highlight the problems

71 cellosis) and animal (bovine brucellosis and foot-and-mouth disease) infections clearly differentiati

72 Hand, foot, and mouth disease is a common childhood illness ca

73 Atypical hand, foot, and mouth disease is caused by a new lineage of Co

74 Hand-foot-and-mouth disease is a serious public health threat

75 disease virus (FMDV), the causative agent of foot-and-mouth disease, is an Aphthovirus within the Pic

76 disease virus (FMDV), the causative agent of foot-and-mouth disease, is an Apthovirus within the Pico

77 st Nile virus), jump dispersal on a network (foot-and-mouth disease), or a combination of these (Sudd

78 arwick model run for the 2001 United Kingdom foot and mouth disease outbreak and compare the efficacy

79 Foot-and-mouth disease outbreaks in non-endemic countrie

80 loped spatio-temporal model of the spread of foot-and-mouth disease, parameterized to match the 2001

81 Every year in June, hand, foot, and mouth disease peaked in north China, whereas s

82 cal, and laboratory data from cases of hand, foot, and mouth disease reported to the Chinese Center f

83 The Global Foot-and-Mouth Disease Research Alliance (GFRA), an inte

84 mine this problem using the specific case of foot-and-mouth disease spreading between farms using the

85 mplifies the severe, atypical cases of hand, foot, and mouth disease that have been reported worldwid

86 terovirus 71 is a picornavirus causing hand, foot, and mouth disease that may progress to fatal encep

87 We performed experimental studies of foot-and-mouth disease transmission in cattle and estima

88 rediction results on three datasets of SAT2 (Foot-and-Mouth disease), two datasets of serotype A (Foo

89 NLS) located at the N-terminal region of the foot-and-mouth disease viral polymerase (3D).

90 n from genetic and epidemiological data in a Foot and Mouth Disease Virus (FMDV) veterinary outbreak

91 sh-ble antibiotic resistance gene, with the foot and mouth disease virus 2A self-cleaving sequence p

92 Foot and mouth disease virus causes a livestock disease

93 The foot and mouth disease virus, a picornavirus, encodes tw

94 flock house virus, human rhinovirus-14, and foot and mouth disease virus.

95 n, livestock can be made less susceptible to foot and mouth disease virus.

96 The foot-and-mouth disease virus (FMDV) "carrier" state was

97 can sterilely protect swine challenged with foot-and-mouth disease virus (FMDV) 1 day later.

98 The ability of foot-and-mouth disease virus (FMDV) 2A to mediate proteo

99 ck in secretion are induced by expression of foot-and-mouth disease virus (FMDV) 3C(pro) and that thi

100 The N-terminal region of the foot-and-mouth disease virus (FMDV) 3D polymerase contai

101 The foot-and-mouth disease virus (FMDV) afflicts livestock i

102 ished data from transmission experiments for foot-and-mouth disease virus (FMDV) and African swine fe

103 s were tested in this study: one recognizing foot-and-mouth disease virus (FMDV) and another recogniz

104 IRESs) of encephalomyocarditis virus (EMCV), foot-and-mouth disease virus (FMDV) and other picornavir

105 e present in highly purified preparations of foot-and-mouth disease virus (FMDV) and poliovirus.

106 the extent to which the genetic diversity of foot-and-mouth disease virus (FMDV) arising over the cou

107 Foot-and-mouth disease virus (FMDV) binds to cell-surfac

108 shown that the leader proteinase (L(pro)) of foot-and-mouth disease virus (FMDV) blocks cap-dependent

109 It has been demonstrated that foot-and-mouth disease virus (FMDV) can utilize at least

110 Foot-and-mouth disease virus (FMDV) causes a fast-spread

111 Foot-and-mouth disease virus (FMDV) causes a highly cont

112 Foot-and-mouth disease virus (FMDV) causes a highly cont

113 use in stabilizing SAT2 vaccines.IMPORTANCE Foot-and-mouth disease virus (FMDV) causes a highly cont

114 Foot-and-mouth disease virus (FMDV) causes a highly cont

115 Foot-and-mouth disease virus (FMDV) causes an acute vesi

116 The genome of foot-and-mouth disease virus (FMDV) differs from that of

117 Isolates of foot-and-mouth disease virus (FMDV) exist as complex mix

118 for the differential laboratory detection of foot-and-mouth disease virus (FMDV) from viruses that ca

119 Two foot-and-mouth disease virus (FMDV) genome sequences hav

120 hin the RNA genome of all seven serotypes of foot-and-mouth disease virus (FMDV) has been developed.

121 Field isolates of foot-and-mouth disease virus (FMDV) have a restricted ce

122 Field isolates of foot-and-mouth disease virus (FMDV) have been shown to u

123 Field isolates of foot-and-mouth disease virus (FMDV) have been shown to u

124 ocked the replication of poliovirus (PV) and foot-and-mouth disease virus (FMDV) in a variety of cell

125 ociated with clearance versus persistence of foot-and-mouth disease virus (FMDV) in micro-dissected c

126 beta8, have been identified as receptors for foot-and-mouth disease virus (FMDV) in vitro.

127 ta(6), have been identified as receptors for foot-and-mouth disease virus (FMDV) in vitro.

128 Foot-and-mouth disease virus (FMDV) induces a very rapid

129 Here, we show that the picornavirus foot-and-mouth disease virus (FMDV) induces the formatio

130 ole of T-lymphocyte subsets in recovery from foot-and-mouth disease virus (FMDV) infection in calves

131 The pathogenesis of persistent foot-and-mouth disease virus (FMDV) infection was invest

132 Foot-and-mouth disease virus (FMDV) initiates infection

133 ecades of investigation, the manner in which foot-and-mouth disease virus (FMDV) interacts with the i

134 shown that the leader proteinase (L(pro)) of foot-and-mouth disease virus (FMDV) interferes with the

135 Translation initiation dependent on the foot-and-mouth disease virus (FMDV) internal ribosome en

136 iral vectors were constructed containing the foot-and-mouth disease virus (FMDV) internal ribosome en

137 Foot-and-mouth disease virus (FMDV) is a highly contagio

138 Nonstructural protein 3A of foot-and-mouth disease virus (FMDV) is a partially conse

139 Foot-and-mouth disease virus (FMDV) is an important anim

140 One of the final steps in the maturation of foot-and-mouth disease virus (FMDV) is cleavage of the V

141 We have previously shown that replication of foot-and-mouth disease virus (FMDV) is highly sensitive

142 Infection by field strains of Foot-and-mouth disease virus (FMDV) is initiated by bind

143 The leader proteinase (L(pro)) of foot-and-mouth disease virus (FMDV) is involved in antag

144 n the initiation of immune responses against foot-and-mouth disease virus (FMDV) is poorly understood

145 domestic animals with chemically inactivated foot-and-mouth disease virus (FMDV) is widely practiced

146 Foot-and-mouth disease virus (FMDV) leader proteinase (L

147 Foot-and-mouth disease virus (FMDV) mediates cell entry

148 Foot-and-mouth disease virus (FMDV) produces one of the

149 eta interferon [IFN-alpha/beta]) can inhibit foot-and-mouth disease virus (FMDV) replication in cell

150 and II IFNs have proven effective to inhibit foot-and-mouth disease virus (FMDV) replication in swine

151 g a comparative analysis, of 103 isolates of foot-and-mouth disease virus (FMDV) representing all sev

152 Infection of cells by foot-and-mouth disease virus (FMDV) results in the rapid

153 Foot-and-mouth disease virus (FMDV) RNA-dependent RNA po

154 Adsorption and plaque formation of foot-and-mouth disease virus (FMDV) serotype A12 are inh

155 ents from human rhinovirus type 2 (HRV2) and foot-and-mouth disease virus (FMDV) to control the trans

156 previously demonstrated that the ability of foot-and-mouth disease virus (FMDV) to form plaques in c

157 Adaptation of field isolates of foot-and-mouth disease virus (FMDV) to grow in cells in

158 Foot-and-mouth disease virus (FMDV) utilizes different c

159 VHH proteins recognizing foot-and-mouth disease virus (FMDV) were used for making

160 The development of a serological test for foot-and-mouth disease virus (FMDV) which is quick and e

161 Foot-and-mouth disease virus (FMDV), a non-enveloped pic

162 However, in foot-and-mouth disease virus (FMDV), a sequence (2A) of

163 the integrin receptors on cultured cells for foot-and-mouth disease virus (FMDV), and high-efficiency

164 Foot-and-mouth disease virus (FMDV), as with other RNA v

165 ily, and for several diverse species such as foot-and-mouth disease virus (FMDV), hemagglutinin (HA)

166 Foot-and-mouth disease virus (FMDV), like other RNA viru

167 Foot-and-mouth disease virus (FMDV), particularly strain

168 Foot-and-mouth disease virus (FMDV), the causative agent

169 Foot-and-mouth disease virus (FMDV), the causative agent

170 " We show that the key replication enzyme of foot-and-mouth disease virus (FMDV), the RNA-dependent R

171 s of representatives of several serotypes of foot-and-mouth disease virus (FMDV), we discovered a put

172 We have previously reported that Foot-and-mouth disease virus (FMDV), which is virulent f

173 mutants were used to map antigenic sites on foot-and-mouth disease virus (FMDV), which resulted in t

174 subsequent evolution of RNA viruses such as foot-and-mouth disease virus (FMDV).

175 ected swine when challenged 1 day later with foot-and-mouth disease virus (FMDV).

176 f the internal ribosome entry site (IRES) of foot-and-mouth disease virus (FMDV).

177 lved in genome packaging in the picornavirus foot-and-mouth disease virus (FMDV).

178 lfate has an important role in cell entry by foot-and-mouth disease virus (FMDV).

179 merous human and animal pathogens, including foot-and-mouth disease virus (FMDV).

180 deoptimize the capsid-coding region (P1) of foot-and-mouth disease virus (FMDV).

181 tionally been used to map antigenic sites on foot-and-mouth disease virus (FMDV).

182 proof of principle concept to the capsid of foot-and-mouth disease virus (FMDV).

183 , we apply the method to two UK epidemics of Foot-and-Mouth Disease Virus (FMDV): the 2007 outbreak,

184 recognizing a putative vaccinal peptide from foot-and-mouth disease virus (FMDV15).

185 peptide binding and explains the ability of foot-and-mouth disease virus 3C(pro) to cleave sequences

186 The X-ray crystal structure of the foot-and-mouth disease virus 3C(pro), mutated to replace

187 agents that produce vesicular lesions, e.g., foot-and-mouth disease virus and others.

188 nked to the gene encoding the 2A protease of foot-and-mouth disease virus and then inserted in frame

189 The foot-and-mouth disease virus encodes two forms of a cyst

190 On extensive passage of foot-and-mouth disease virus in baby hamster kidney-21 c

191 n a 4H junction derived from domain 3 of the foot-and-mouth disease virus internal ribosome entry sit

192 (6) and 2 x 10(7) c.f.u./ml, indicating that foot-and-mouth disease virus IRES provides high-titer bi

193 Because foot-and-mouth disease virus IRES structure depends on l

194 a vector with a multiple cloning site 3' to foot-and-mouth disease virus IRES, was used to construct

195 of the O(1) British field strain serotype of foot-and-mouth disease virus is a high-affinity ligand f

196 Foot-and-mouth disease virus is a highly contagious path

197 A genetic variant of foot-and-mouth disease virus lacking the leader proteina

198 ar to those of core catalytic domains of the foot-and-mouth disease virus leader protease and coronav

199 we use these methods to analyze data from a foot-and-mouth disease virus outbreak in the United King

200 Venus and a puromycin-resistant gene via the foot-and-mouth disease virus self-cleaving peptide T2A.

201 odels to predict the antigenic similarity in foot-and-mouth disease virus strains and in influenza st

202 opy of the genome-linked protein, VPg wheras foot-and-mouth disease virus uniquely encodes three copi

203 s in innate responses against infection with foot-and-mouth disease virus was analyzed on consecutive

204 on mediated a salient genome segmentation of foot-and-mouth disease virus, an important animal pathog

205 henotype has been documented for poliovirus, foot-and-mouth disease virus, and coxsackievirus B3 and

206 cally important members, such as poliovirus, foot-and-mouth disease virus, and endomyocarditis virus.

207 icornavirus family, including poliovirus and foot-and-mouth disease virus, are widespread pathogens o

208 AVPNLRGDLQVLAQKVART (A20FMDV2), derived from foot-and-mouth disease virus, as a potent inhibitor of a

209 Following infection with foot-and-mouth disease virus, expression of CD62L and CD

210 the prominent G-H loop of the VP1 protein of foot-and-mouth disease virus, raised substantial levels

211 The larger picornavirus IRESs (those of foot-and-mouth disease virus, rhinovirus, encephalomyoca

212 ar viruses, including all seven serotypes of foot-and-mouth disease virus, two serotypes of vesicular

213 lved in genome packaging of the picornavirus foot-and-mouth disease virus.

214 ctive peptide (A20FMDV2) derived from VP1 of foot-and-mouth disease virus.

215 2A self-processing peptide derived from the foot-and-mouth disease virus.

216 ere experimentally infected via aerosol with foot-and-mouth disease virus.

217 xsackievirus, rhinovirus, enterovirus 71 and foot-and-mouth disease virus.

218 imal pathogens: classical swine fever virus; foot-and-mouth disease virus; vesicular stomatitis virus

219 The foot-and-mouth-disease virus (FMDV) utilizes non-canonic

220 from high affinity ligands of alpha v beta6 (foot-and-mouth-disease virus, latency associated peptide

221 polymerases from poliovirus, rhinovirus, and foot-and-mouth disease viruses.

222 CVA--the predominant pathogens for the hand, foot, and mouth disease--was observed in recent years.

223 TB controls during a nationwide epidemic of foot and mouth disease, which substantially delayed remo

224 for frequent large-scale outbreaks of hand, foot, and mouth disease worldwide and represent a major