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2 y for designing antagonists and prove useful for elucidating activation mechanisms of other receptors
3 cores represents a new experimental platform for elucidating additional aspects of capsid disassembly
5 lness of the newly generated V2R mutant mice for elucidating and testing new strategies for the poten
6 on and self-cleaning mechanisms is essential for elucidating animal behaviours and rationally designi
7 Our findings provide a molecular framework for elucidating auxin-mediated control of plant cell exp
9 eptors have been an outstanding model system for elucidating basic principles in sensory transduction
10 proteomic approaches will set a new standard for elucidating biochemical mechanisms of UB-driven sign
11 Molecular imaging holds considerable promise for elucidating biological processes in normal physiolog
12 To demonstrate the power of this library for elucidating biological processes, we analyzed the li
13 , we provide tools for genomic discovery and for elucidating biologically relevant mechanisms of gene
14 shown to have great potential as candidates for elucidating biomarkers and pathway perturbations ass
16 ons between neural oscillations, is critical for elucidating brain dysfunction in neuropsychiatric di
18 ate cortices, provides a unique lesion model for elucidating brain structures that control autonomic
22 how Ras proteins are regulated is important for elucidating cell signaling pathways and identifying
24 king in plants, but also an important system for elucidating chromatin-based gene regulation more gen
25 e cistrome and epicistrome maps are critical for elucidating complex transcriptional networks that un
26 bal plant trait spectrum provides a backdrop for elucidating constraints on evolution, for functional
27 e production that has potential implications for elucidating CT-B adjuvant activity in the absence of
28 s of previously uncharacterized TFs but also for elucidating dependencies, both local and nonlocal, b
29 ink protein sequence to binding are valuable for elucidating determinants of protein interaction but
30 nderstanding disease caused by K. kingae and for elucidating diagnostic parameters in human patients.
31 findings offer important tools and insights for elucidating differences between normal and malignant
33 ration and flow impairment and may be useful for elucidating disease pathogenesis, progression, and r
36 ulations may offer a broadly useful strategy for elucidating effects of genetic variation on infectio
37 es validate the utility of the Lu-iPSC model for elucidating epigenetic mechanisms contributing to pu
39 ysis, and will probably prove to be critical for elucidating etiologies of the various lymphoid neopl
40 its determination is likely to be essential for elucidating functional heterogeneity of these cells
41 emonstration should encourage the use of MEG for elucidating functional networks mediating fear-relat
42 voir host studies provide a rich opportunity for elucidating fundamental immunological processes and
44 y to perturb genes in human cells is crucial for elucidating gene function and holds great potential
45 l of gene expression or deletion is critical for elucidating gene function in biological systems.
46 A interference (RNAi) is a powerful approach for elucidating gene functions in a variety of organisms
48 uencing (NGS) is emerging as a powerful tool for elucidating genetic information for a wide range of
51 infection and establish a proteomic resource for elucidating host mechanisms that regulate fungal int
53 ous Fc glycoforms thus provide a useful tool for elucidating how a fine Fc N-glycan structure precise
54 t changes with signaling events is essential for elucidating how cells regulate this essential ion.
55 ake the arthropod body plan a valuable model for elucidating how changes in development create divers
56 DNA methylation offers an excellent example for elucidating how epigenetic information affects gene
57 more, our simple task design provides a tool for elucidating how neuronal activity relates to sensory
60 ation, and degradation of mRNAs is important for elucidating how these processes occur in both virus-
62 tanding of the assembly of membrane proteins for elucidating intramolecular interactions, and they of
63 r (super-multiplex) optical imaging approach for elucidating intricate interactions in complex biolog
64 ular nature of Hec-6st regulation is crucial for elucidating its function in development and disease.
65 ms involved in the metabolism of NO is vital for elucidating its many roles in cellular signaling and
66 rt here a feature of the phenomenon relevant for elucidating its mechanism: Despite their higher dens
67 corticospinal system is especially important for elucidating its role in recovery of limb control aft
68 d computational methods offers the potential for elucidating key aspects of protein folding that are
69 tivated foci and provides a common framework for elucidating key features of brain and cognitive deve
70 the potential of systems glycobiology tools for elucidating key glycan biomarkers and potential ther
71 ive tool for analyzing cellular behavior and for elucidating key properties of the intricate networks
72 noncanonical signaling, are extremely useful for elucidating key signal transduction pathways essenti
73 y of incompletely characterized proteins and for elucidating larger-scale patterns of proteome organi
74 hodology suggests a potential useful pathway for elucidating lightning energy and damage potential of
75 f cross-linked amino acids is a rapid method for elucidating low-resolution protein tertiary structur
76 e CNS neuronal activation is a powerful tool for elucidating mammalian brain function in health and d
77 h has been conducted utilizing animal models for elucidating mechanisms and developing therapeutics,
78 ing the development of the VTA is imperative for elucidating mechanisms mediating adolescent vulnerab
79 se that Nrl(-/-) retina may serve as a model for elucidating mechanisms of cone homeostasis and degen
81 etworks into genetic analysis offers promise for elucidating mechanisms of life history evolution.
82 he nervous system and has enormous potential for elucidating mechanisms that mediate neuron-glia inte
85 rey Hall, Michael Rosbash, and Michael Young for elucidating molecular mechanisms of the circadian cl
86 gbirds represent an important model organism for elucidating molecular mechanisms that link genes wit
87 pment of Kallmann syndrome and provide tools for elucidating mutations that underlie complex hormonal
89 ly diverse enolase superfamily is a paradigm for elucidating Nature's strategies for divergent evolut
91 investigations of 22q11DS as a genetic model for elucidating neurobiological mechanisms underlying th
92 the enteric nervous system (ENS) is critical for elucidating neurological function in the gastrointes
93 roversies in this field as well as prospects for elucidating neurotransmitter mechanisms in addiction
94 icity to memory formation, with implications for elucidating NMDAR-related dysfunction in disease-rel
95 n a systems biology approach holds potential for elucidating novel genetic markers and mechanisms for
97 hese conclusions have important implications for elucidating other drug resistance phenomena and emph
100 Understanding these processes is crucial for elucidating pathomechanisms of connective tissue dis
101 ychiatry potentially provides powerful tools for elucidating pathophysiology that may inform both dia
103 a function of (bio)availability is critical for elucidating persistence, accumulation, and toxicity.
104 hat longitudinal recording will be essential for elucidating plasticity mechanisms within cortical mi
105 e PAD as a powerful predictive modeling tool for elucidating platelet adhesive phenomena under flow.
107 echniques however, are not adequately suited for elucidating possible biomarker candidates from withi
108 cal research, and it is a very powerful tool for elucidating protein interactions in either dynamic o
109 We anticipate rMAPS will be a useful tool for elucidating RBP regulation of alternative exon splic
110 e novel findings have important implications for elucidating regional differences in cholinergic sign
111 inued progress in this area will be critical for elucidating roles of monocytes in disease and for de
112 dicted design flaws in synthetic genomes and for elucidating rules governing codon choice will be cru
113 differentiation of epidermal stem cells, and for elucidating signaling pathways involved in those pro
114 he spacing between ligands would be valuable for elucidating structure-activity relationships and for
115 tance of super-resolution imaging approaches for elucidating structure-function relationships of dend
116 ctivatable binding-sites, thus opening doors for elucidating subunit arrangement and anthelmintic sel
118 f SecA is still lacking and will be critical for elucidating the bacterial protein transport mechanis
119 in heart rate (f H ) has been used as a tool for elucidating the balance between sympathetic and para
122 and to assess gene-environment interactions for elucidating the behavioral and physiological dysfunc
123 dling large-scale metabolomics data, methods for elucidating the biochemical structure and function o
124 ivatives by natural amphiphiles is essential for elucidating the biological and environmental implica
125 ology in SMA, and can serve as a preparation for elucidating the biological basis of synapse loss, an
126 esults provide information that is important for elucidating the biological function and vaccine effi
128 ption factor activity is an appealing avenue for elucidating the cell biology mediated by transcripti
129 pectroscopies are useful complementary tools for elucidating the change in the structure of protein d
132 ormal mode analyses have proven to be useful for elucidating the collective dynamics intrinsically ac
133 ructures provide an essential starting point for elucidating the complex gating mechanisms of TRPM4 a
135 with systems modeling analysis is essential for elucidating the complexity in crosstalk of auxin, cy
136 t the utility of the FCD-pi(PG) relationship for elucidating the contribution of matrix macromolecule
137 haracterization of T-pro builds a foundation for elucidating the contributions of inflammation to cut
138 rove useful for preclinical drug studies and for elucidating the developmental origins of pediatric n
139 s on the mechanisms of cone degeneration and for elucidating the different roles of Rds in rods and c
140 gical and pathogenic conditions is important for elucidating the disease mechanism and identifying po
141 luorescence approaches have been widely used for elucidating the dynamics of protein-membrane interac
142 These results provide a quantitative basis for elucidating the earliest cell response to the detect
143 igner receptor complexes are a valuable tool for elucidating the effects of activating particular rec
145 ct biofilms and open up an additional avenue for elucidating the emergence and fate of the different
146 ll differentiation have been primary drivers for elucidating the epigenetic control of cellular ident
147 derstanding these mechanisms may be critical for elucidating the etiology of the obesity epidemic.
148 genetic basis of phenotypic differences and for elucidating the evolutionary history of the species.
149 ovel model presented here can provide a tool for elucidating the flow mechanisms of fluids in closed
150 ots is an important problem in biology, both for elucidating the folding mechanisms of larger ribozym
154 at the nebulin knockout model is well suited for elucidating the functional basis of muscle weakness
155 Our study delineates a molecular framework for elucidating the functional links between transcripto
156 ent gene activation and provides a framework for elucidating the functions of CRL adaptor proteins.
159 as these samples serve as the best platforms for elucidating the fundamental properties of plasmonic
160 t stem cells (hPSCs) offer a unique platform for elucidating the genes and molecular pathways that un
161 MG regulatory network provides a foundation for elucidating the genetic and cellular basis of a mode
162 ted analysis of mouse behavior will be vital for elucidating the genetic determinants of behavior, fo
163 ein kinase A isoforms, providing a framework for elucidating the global organization of each holoenzy
164 ile also serving as an experimental platform for elucidating the in vivo specificity and function of
165 ography patterning on elastomeric substrates for elucidating the influences of mechanical cues on neu
166 h experiments constitute a powerful strategy for elucidating the inherent selectivity of acyl formati
167 tion of a new protein reveals that the quest for elucidating the intracellular B12 highway is still f
168 amily-based methods, it is an effective tool for elucidating the involvement of RVs in the etiology o
169 proaches and furnishes a schematic framework for elucidating the ligand-protein interactions of other
170 ular to the systems, make it an ideal system for elucidating the logic by which the nervous system or
171 tructure of the transition state is critical for elucidating the mechanism behind how proteins fold a
172 plasma trioxanes as well as molecular probes for elucidating the mechanism of action of the DART clas
173 sing the presence of BAT deposits as well as for elucidating the mechanism of CB1 antagonist-mediated
174 sed rat embryonic pancreatic explant culture for elucidating the mechanism of Leu action on beta-cell
175 ure (high-T(c)) superconductors is important for elucidating the mechanism of superconductivity.
176 and molecular approaches have been critical for elucidating the mechanism of the mammalian circadian
177 with high-resolution spectroscopic data, and for elucidating the mechanism of water-splitting in PSII
178 Understanding top-down attention is crucial for elucidating the mechanisms by which we can filter se
179 of the planarian digestive system as a model for elucidating the mechanisms controlling postembryonic
180 ovary provide a genetically tractable model for elucidating the mechanisms controlling such behavior
181 traverse to generate mature progeny is vital for elucidating the mechanisms governing cell fate decis
182 e need for new experimental exposure devices for elucidating the mechanisms governing ecosystemic PAH
185 Here, we review computational approaches for elucidating the mechanisms of both intended and unde
186 ium signaling pathways in cells is essential for elucidating the mechanisms of both normal cell funct
187 lished cell lines, will provide a foundation for elucidating the mechanisms of cellular reprogramming
189 eveal the potential of RNA aptamers as tools for elucidating the mechanisms of co-assembly in amyloid
190 e checkpoint kinases and provide a framework for elucidating the mechanisms of DNA replication fork s
191 bacterial effectors are, therefore, crucial for elucidating the mechanisms of Legionella virulence.
192 eceptors (AMPARs) is controlled is important for elucidating the mechanisms of neuronal function.
193 environmental forcing and unparalleled tools for elucidating the mechanisms that lead to the developm
194 es describe a new and robust in vitro system for elucidating the mechanisms underlying human stomach
195 uronal manipulation should provide the basis for elucidating the mechanisms underlying somatosensatio
196 global kinome may provide crucial knowledge for elucidating the mechanisms underlying the cytotoxic
197 r subtypes may have significant implications for elucidating the mechanisms underlying the distinct p
198 te the power of transition path measurements for elucidating the microscopic determinants of folding.
200 ton) in insects has served as a useful model for elucidating the molecular and cellular mechanisms of
201 ght the power of gene complementation assays for elucidating the molecular basis of genetic diseases.
202 ies that utilize global gene expression data for elucidating the molecular basis of systemic sclerosi
203 ctures from sequences becomes very important for elucidating the molecular details and functions of t
204 raploid Arabidopsis will be a powerful model for elucidating the molecular details of these processes
207 tions with the immune system and are a basis for elucidating the molecular mechanism of NS1 function.
208 on for identifying genes specific for IC and for elucidating the molecular mechanism underlying this
210 studies of individual mutations are critical for elucidating the molecular mechanisms of ALS and rela
211 for its lifetime, constitutes a model system for elucidating the molecular mechanisms of personality.
212 oreceptors are widely used as a model system for elucidating the molecular mechanisms of transmembran
214 ancer development as they have proved useful for elucidating the molecular mechanisms underlying tumo
215 cal for the development of new therapies and for elucidating the molecular pathogenesis of this major
216 eductionist approach, provide valuable tools for elucidating the nature of toxic forms of alpha-syn i
217 le cell RNA-Seq analysis holds great promise for elucidating the networks and pathways controlling ce
218 provide a quantitative behavioral background for elucidating the neural basis of plume tracking using
220 mouse is an important experimental resource for elucidating the neural mechanisms of social anxiety,
221 tility of the S1 strain as a tractable model for elucidating the neural, molecular and genetic basis
222 uide genetic testing, and suggest hypotheses for elucidating the neurobiology of a culprit subcortica
224 , therefore, serve as extremely useful tools for elucidating the neuropathological mechanisms that un
225 Thus, this system serves as a new model for elucidating the oncogenic contribution of mutant K-r
226 local (residue) scales is an emerging trend for elucidating the organization and function of the cel
227 was performed at the ZORA-TPSS-D3/TZ2P level for elucidating the origin of the selectivity preference
228 porary and resurrected enzymes holds promise for elucidating the origins and activities of other carb
229 and introduces new analytical opportunities for elucidating the origins and biogeochemical propertie
230 erred to as evo-devo, provide powerful tools for elucidating the origins of mechanisms for establishi
231 arophytes occupy a key phylogenetic position for elucidating the origins of such signalling systems(2
232 he regulatory mechanisms involved is crucial for elucidating the pathogenesis of and will provide new
233 les of cardiac progenitor cells is important for elucidating the pathogenesis of congenital and acqui
234 standing catecholamine metabolism is crucial for elucidating the pathogenesis of hereditary hypertens
235 isease, it provides a valuable genetic model for elucidating the pathogenic mechanism of the WDR81 mu
236 tions plans, and modify behavior, as well as for elucidating the pathophysiology of psychiatric disea
237 t of cervical lesions, and establish a model for elucidating the pathway to cervical cancer following
238 diseases, opening up unprecedented potential for elucidating the pathways and processes of disease.
239 these findings have significant implications for elucidating the phase transformation and transport o
240 ent proxies therefore offer a novel approach for elucidating the phenomenology of the nuclear firebal
241 t tissues, thus providing a versatile system for elucidating the physiological gene function in viabl
242 and are mainly used as pharmacological tools for elucidating the physiological role of extracellular
243 hese biotransformations, which are essential for elucidating the possible transformation products and
244 sizes the utility of Drosophila transgenesis for elucidating the precise mechanisms of Cry-mediated m
245 These findings have important implications for elucidating the previously recognized but little und
246 embedded, providing an excellent opportunity for elucidating the properties of the damaged DNA duplex
247 this work not only provides a unique system for elucidating the reaction mechanism of rhomboid but a
248 ock CD81-HCV interaction and also pave a way for elucidating the recognition mechanisms of diverse te
249 s highlight the promise of genome sequencing for elucidating the recombinational dynamics of plant mi
250 tal phase and provides an effective platform for elucidating the redox reaction and oxygen diffusion
251 of expression data also lays the foundation for elucidating the regulatory networks downstream of th
253 organisms, ex vivo assays have been crucial for elucidating the relationships among hematopoietic st
254 e of microorganisms has been a powerful tool for elucidating the relationships between animal hosts a
255 probe tomography makes it a unique platform for elucidating the relative stability and interactions
256 ical impact of costly protein production and for elucidating the resulting regulatory mechanisms.
257 polymorphism of CFH and lays the groundwork for elucidating the role of CFH in AMD pathogenesis.
258 or dissecting the CN interaction network and for elucidating the role of CN in human health and disea
259 riazole CpIMPDH inhibitors provide new tools for elucidating the role of IMPDH in C. parvum and may s
261 folding nucleation, and provide a framework for elucidating the role of lipid-induced conformational
262 the pathways of phospholipid metabolism and for elucidating the role of LPL species in signal transd
263 rgan systems of mice, which may be important for elucidating the role of Mincle in the control of myc
264 me-points, and provide a critical foundation for elucidating the role of postcopulatory sexual select
265 d by Mahlon R. DeLong and Alim-Louis Benabid for elucidating the role of the subthalamic nucleus in m
266 CMBs and suggest possible future approaches for elucidating the role of these common lesions as mark
267 type (wt) virus are extremely valuable tools for elucidating the roles of specific genes in virus pat
268 ivo.This unique tool provides a new resource for elucidating the roles of striatopallidal MSN Galphas
269 1 could be used as specific molecular probes for elucidating the roles of the receptor in different t
270 ontext of a protein fold provides a strategy for elucidating the sequence-structure-fitness relations
271 computational approach provides a framework for elucidating the structural and functional properties
272 roach developed here is generally applicable for elucidating the structural basis of cholesterol's ef
273 represents a previously undescribed approach for elucidating the structural basis of protein binding
274 n of the cortex is of fundamental importance for elucidating the structural principles that underlie
275 es described here may be particularly useful for elucidating the structural properties of Cu that det
276 in clinical diagnosis and important reagents for elucidating the structure and function of intracellu
277 g of neural activity is a powerful technique for elucidating the structure and function of neural cir
278 on pathways, and suggest possible strategies for elucidating the structures of glucosamine-derived su
279 significant on their own, are not effective for elucidating the synergistic qualities of the numerou
280 class of compounds and provides a foundation for elucidating the timing and mechanisms of their biosy
282 se or immunological interventions as well as for elucidating the underlying mechanisms of immunity.
283 orders (ASD) offer tremendous potential both for elucidating the underlying neurobiology of ASD and i
285 Here we present a widely applicable strategy for elucidating the virulence components of a pathogen p
287 eir molecular fundamentals is a prerequisite for elucidating their aberrant activities in diseases su
288 actions at the atomic level is critical both for elucidating their biological mechanisms of action an
289 as ligands for ALK and LTK and set the stage for elucidating their roles in development and disease s
291 e (OSBS) family is an excellent model system for elucidating these principles because it has many hig
293 Neurons are a potentially very useful system for elucidating this significance, because they are high
294 xpression intensity is an effective strategy for elucidating transcriptional cis-regulatory logic.
295 ur integrated approach provides a foundation for elucidating transcriptional networks guiding the dev
297 ression and cellular activity are invaluable for elucidating underlying physiological processes and w
298 cess enzyme-bound intermediates are critical for elucidating unresolved polyketide and nonribosomal p
299 es the capability of (1)H spin diffusion NMR for elucidating water interactions with ion channels, wa
300 iciency virus (SIV) in monkeys may be useful for elucidating what is needed from a vaccine in order t
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