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2 llenges, we present a novel algorithm DLCpar for inferring a most parsimonious (MP) history of a gene
3 diversity, but this is nonetheless essential for inferring accurately the history of species with ove
5 ion concern, and provide a general framework for inferring allele distribution and persistence and in
6 ve methods for estimating site allele count, for inferring allele frequency spectrum and for associat
7 lihood, and distance methods can all be used for inferring amino acid sequences of the proteins of an
8 rrangements has become a very powerful means for inferring ancient evolutionary relationships, since
10 ple algorithms provide a stronger foundation for inferring and characterizing regulatory programs ass
12 and discuss a suite of algorithms and tools for inferring and scoring regulator networks upstream of
16 These findings establish Collage as a method for inferring biological knowledge from the integration
17 Sparse Gaussian graphical models are popular for inferring biological networks, such as gene regulato
18 ck size estimates, we introduce a new method for inferring bottleneck sizes that accounts for these f
20 e have exploited provides general principles for inferring catalytic activity from structural studies
21 P method quantifies confidence probabilities for inferring causal structures and thus leads to more r
24 a method, similar to regression calibration, for inferring changes in the distribution of white blood
25 od based on water mass transformation theory for inferring changes in the water cycle from changes in
26 of certain surrogate end points can be used for inferring clinically significant vaccine effects and
27 integer copy number, few have been designed for inferring CNV haplotypic phase and none of these are
28 es, predicting CNV allelic configuration and for inferring CNV haplotypic phase from SNP/CNV genotype
29 of genome-scale data can serve as the basis for inferring combinatorial regulation and for building
30 raph diffusion kernel as a unified framework for inferring complex/pathway membership analogous to "f
31 NP-SEQ is a statistical model-based approach for inferring copy number profiles directly from high-co
32 arkov Models (HMM) to analyze SNP array data for inferring copy numbers and loss-of-heterozygosity (L
33 Although there are many methods available for inferring copy-number variants (CNVs) from next-gene
34 OV) which combines three distinct approaches for inferring covariation signals from multiple sequence
35 we demonstrate the usefulness of the method for inferring demographic history, especially recent cha
36 We propose a hierarchical Bayesian model for inferring differences between groups of samples more
37 the existence of many programs and databases for inferring different protein functions, a pipeline th
39 fers to a family of computational techniques for inferring disease genes through a set of training ge
40 These detailed data have been proven useful for inferring disease transmission to a more refined lev
41 mirConnX is a user-friendly web interface for inferring, displaying and parsing mRNA and microRNA
43 We present MDSINE, a suite of algorithms for inferring dynamical systems models from microbiome t
45 ance of quantitative seasonal abundance data for inferring ecological distributions and demonstrate s
46 dy, we test the suitability of these methods for inferring ecological interactions by constructing ne
48 We investigated the sample sizes required for inferring exclusion and linkage, for various combina
52 Interspecies comparison is a powerful tool for inferring function from genomic sequence and could u
54 er 2/3 pyramidal neurons to validate methods for inferring functional connectivity in a setting where
56 irst is a computationally inexpensive method for inferring functional information from protein crysta
60 ns, and (3) developed an efficient algorithm for inferring gene expression rate constants from the mo
61 itance, operon and gene fusion-based methods for inferring gene function and reconstructing cellular
62 genetic screens provide a powerful approach for inferring gene function on the basis of the phenotyp
63 , we present GINI, a machine learning system for inferring gene interaction networks from Drosophila
64 ntal data are a valuable, but limited source for inferring gene regulation mechanisms on a genomic sc
66 propose an improved gene clustering approach for inferring gene signaling pathways from gene microarr
67 he differences that do exist are informative for inferring general principles about the holistic evol
68 efrontal cortex (VMPFC) activation increased for inferring generous play and decreased for inferring
69 ful for identifying an appropriate technique for inferring genetic networks and for interpreting the
70 We have developed and implemented a method for inferring genetic regulatory networks for time serie
71 erest in developing computational techniques for inferring genetic regulatory networks from whole-gen
72 sequence comparison is particularly powerful for inferring genome function and is based on the simple
73 approach is a model-based imputation method for inferring genotypes at observed or unobserved SNPs,
74 ly Bayesian approaches (originally developed for inferring geographic spread and rates of molecular e
75 ications for sawfish conservation as well as for inferring habitat residency of euryhaline elasmobran
77 three previously published Bayesian methods for inferring haplotypes from genotype data in a populat
78 we believe that polyHap, our proposed method for inferring haplotypic phase from genotype data, will
79 an overgeneralization of adaptive mechanisms for inferring harmful intentions and the ability to caus
83 archy affect the performance of five methods for inferring hierarchies, (2) propose an amendment that
86 on penalties in the most widely used methods for inferring homology by sequence alignment, including
89 technology has provided a great opportunity for inferring human demographic history by investigating
91 rdiffusive motion, is of particular interest for inferring information about the dynamics of the cyto
93 but although many methods have been proposed for inferring integer copy number, few have been designe
94 e capacity for curiosity and exploration and for inferring internal models of the external world.
96 , we present OncoNEM, a probabilistic method for inferring intra-tumor evolutionary lineage trees fro
98 c variation along a chromosome may be useful for inferring its evolutionary history and for revealing
101 applying CIBERSORT, a computational approach for inferring leukocyte representation in bulk tumor tra
103 We present a new haplotype-based approach for inferring local genetic ancestry of individuals in a
106 ogeneous Bayesian analysis of variance model for inferring loci involved in recent selective sweeps b
107 ate and more efficient than existing methods for inferring locus-specific ancestries, enabling it to
108 working clinician and their predictive power for inferring long term viral eradication from short ter
109 hlights contagion maps also as a viable tool for inferring low-dimensional structure in networks.
111 pproach is the use of computational modeling for inferring mechanisms which generate observed behavio
112 trol methods, and provides a powerful method for inferring mechanistic relationships underlying biolo
115 tudies of Buchnera have provided a new means for inferring metabolic capabilities of the symbionts an
116 easuring macro- and mesoscopic structure and for inferring microstructural properties; we also descri
120 Quantitative microscopy is a valuable tool for inferring molecular mechanisms of cellular processes
122 recently been proposed as a powerful method for inferring molecular phylogenies, and it has been rep
123 e developed an integrated, scalable strategy for inferring multiple human gene interaction types that
125 werful experimental-computational technology for inferring network models that predict the response o
126 ruction of large networks, we developed Tool for Inferring Network of Genes (TINGe), a parallel mutua
127 rrelational methods are increasingly popular for inferring networks from co-occurrence and time serie
129 principle demonstration of a novel framework for inferring, noninvasively, neuromodulatory influences
136 ause it has been shown that they can be used for inferring participation in a study if the individual
140 ggesting that these loci are not appropriate for inferring phylogenetic relationships among species.
141 amino acid sequences is a powerful approach for inferring phylogenetic relationships and for compari
142 ere, we present a novel computational method for inferring phylogenetic relationships from partial se
144 termining the molecular basis of adaptation, for inferring phylogenies and for engineering novel prot
145 sure and fast running time make MulRF useful for inferring phylogenies from large collections of gene
147 esent a principled likelihood-based approach for inferring physical models of TF-DNA binding energy f
149 led to the development of new methodologies for inferring population history and refuelled the debat
150 dicate that the modified SG method is useful for inferring positive selection at codon sites where ne
154 understanding the dynamics of adaptation and for inferring properties of an organism's fitness landsc
155 al effects invalidates the standard approach for inferring properties of spontaneous mutation and nec
158 into ProDy, a computational toolbox designed for inferring protein dynamics from experimental and the
159 ervation is an important, established method for inferring protein function, modularity and specifici
167 n widely applied population genetics methods for inferring recombination rates, for detecting selecti
168 SHUS, that implements three exact algorithms for inferring regions of hemizygosity containing genomic
169 In this paper, we present a novel framework for inferring regulatory and sequence-level information
171 h motifs in genome sequences is a major goal for inferring regulatory networks yet has been hampered
172 e basal tracheophyte genome, which is useful for inferring relationships among bryophyte lineages.
173 to stimulate development of analytical tools for inferring relationships between somatic changes and
174 actions (i.e. sampling effort) are necessary for inferring reliable dominance hierarchies, nor are th
178 t software implementing a model-based method for inferring ROH in genome-wide SNP datasets that incor
184 ession for Signaling Determination (DESIDE), for inferring signaling activity from microarray measure
185 p and protein modification are indispensable for inferring signalling pathways from PPI networks.
187 ch techniques demonstrate high success rates for inferring 'simple' genomic segments, they are confou
188 cleotide substitutions, a learning algorithm for inferring site-specific substitution biases directly
189 es at Parkfield, California, provide a means for inferring slip rate at depth throughout the active f
193 C) model has emerged as a powerful framework for inferring species phylogenies while accounting for a
194 ing species tress) is a new software package for inferring species trees while accommodating uncertai
195 ifying downstream snapshot measures required for inferring specific dynamical features of upstream si
197 unodeficiency virus type 1 (HIV-1) is useful for inferring structural and/or functional constraints a
201 novo ChIP-seq peak prediction and is useful for inferring TF-binding peaks in new experimental condi
203 any particular season is an unreliable basis for inferring that the year-round average kill rate woul
204 We describe a machine-learning approach for inferring the activity levels of all unexplored sing
206 ak repair (HDR) functional assay as a method for inferring the clinical relevance of VUS in the DBD o
207 oPlotter, an unbiased segmentation algorithm for inferring the compositional organization of genomes.
209 GENIE implements a statistical framework for inferring the demographic history of a population fr
210 ns and apes may provide valuable information for inferring the demographic history of these species,
212 informed choice of outgroup species suitable for inferring the directions of changes, including testi
213 90, Jotun Hein proposed using this criterion for inferring the evolution of sequences subject to reco
214 with diverse evolutionary models, a pipeline for inferring the evolutionary history of a gene family
215 algorithms, we built an integrated pipeline for inferring the evolutionary history of a given gene f
216 tionary alignment modeler, called "Ortheus," for inferring the evolutionary history of a multiple ali
220 ac Ca2+ release process and a general method for inferring the functional properties of transmembrane
221 (PANTHER) is a comprehensive software system for inferring the functions of genes based on their evol
222 a an unsupervised machine learning algorithm for inferring the gene targets of sets of TF binding sit
223 easonal migration has long posed a challenge for inferring the geographic origins of migratory specie
224 , and uses less memory than existing methods for inferring the human genome at high resolution (10 kb
228 mptions leads to similar solution strategies for inferring the model parameters in both variable type
229 robust, efficient, assumption-free approach for inferring the molecular mechanisms that underlie the
230 al areas, it also has important implications for inferring the nature and epidemiological consequence
231 t suggest that this property would be useful for inferring the nature of linked selection either.
232 ter estimation and model selection technique for inferring the number and configuration of promoter s
234 ian model comparison then provides machinery for inferring the optimal order over the group of subjec
236 s is an essential tool of classical genetics for inferring the order of function of genes in a common
237 ation, we have developed an automatic method for inferring the origins of DBD families and their spec
240 le to the number of synonymous substitutions for inferring the phylogenetic tree in the SG method, an
241 characters of each type that have been used for inferring the phylogeny of mammals, we find that on
243 for identifying the optimal feature lengths for inferring the phylogeny of prokaryotes, strictly spe
244 rate an ST, which results in a powerful tool for inferring the population structure of this pathogen,
245 studies mapping genotypes to phenotypes and for inferring the power of natural selection in human hi
246 with respect to alternative parsimony rules for inferring the presence of precursor architectures in
247 e Gibbs sampler is described, and procedures for inferring the probability of yet to be observed futu
248 sts, we also developed an in silico approach for inferring the relative impact of a mutation on RC ba
251 promising two-dimensional chemical strategy for inferring the secondary and tertiary structures that
253 ly, I use the distance-based Bayesian method for inferring the single most likely ancestral codon fro
254 flexible and computationally feasible method for inferring the sources of aneuploidy is thus crucial.
255 icle we present a novel computational method for inferring the strain tree despite massive gene tree
256 gnitude over the methods reported previously for inferring the structure of dynamic networks, such as
257 boundary, the location of which is important for inferring the trajectories of 'suspect' terrain acro
258 mporal dynamics of brain activity is crucial for inferring the underlying synaptic and nonsynaptic me
262 (VNTR)-based clustering, it was insufficient for inferring transmission in the majority of cases.
263 study, we test previously described methods for inferring transmission stage investment against simu
264 This work highlights a powerful technology for inferring transport function and quantifying nutrien
265 implemented in publicly available software, for inferring tumor phylogenies on data from potentially
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