ライフサイエンスコーパス: for the first time

1 ure from higher than room temperature to T C for the first time.

2 was synthesized by a facile synthesis method for the first time.

3 els in murine ageing and OA joints and serum for the first time.

4 rs with molecular proton reduction catalysts for the first time.

5 of sapotexanthin to human plasma was proven for the first time.

6 meta-C-H activation process is demonstrated for the first time.

7 ystalline films of high chemical purity Li2S for the first time.

8 d BP nanosheets in cancer cells are revealed for the first time.

9 pplied for Ag NPs analysis with CE-SP-ICP-MS for the first time.

10 rous and nonmetalliferous sites is presented for the first time.

11 e stripping voltammetry (AdSV) was described for the first time.

12 opy to study chiral recognition is described for the first time.

13 and three in Pithecia, some of them reported for the first time.

14 ays of the reactive UV filters were proposed for the first time.

15 estalotioprolides G and H has been developed for the first time.

16 e ferroelectric effect has been demonstrated for the first time.

17 allows objective quantification of outcomes for the first time.

18 is now available in a quaternary AA context for the first time.

19 ockout mice to investigate its roles in vivo for the first time.

20 n behavior of Rumenic acid (RA) is presented for the first time.

21 been characterized in detail and quantified for the first time.

22 ogeneous ion transport of biological samples for the first time.

23 oto-bioreactor (PPBR), was built and applied for the first time.

24 graphene conductive photodetector is studied for the first time.

25 S2 and isotropic WS2 monolayers are reported for the first time.

26 sor of metal and carbon sources is presented for the first time.

27 roughts from 1981 to 2013 were reconstructed for the first time.

28 ivity for label free DNA and protein sensing for the first time.

29 levels 2 and 4 of SRM 955c are reported here for the first time.

30 nding sodium selective sensors were obtained for the first time.

31 aza-annulation of enynyl azides is reported for the first time.

32 a human genome on this platform was achieved for the first time.

33 diazo-beta-keto sulfoxides has been achieved for the first time.

34 ve nucleus (KEN), for nanoparticle formation for the first time.

35 of traditional fermentation was investigated for the first time.

36 s at different nodes of the tree and provide for the first time a clear distinction of stem and crown

37 sent results in an ancient vertebrate reveal for the first time a collection of brain targets of Galp

38 V-positive cells.IMPORTANCE We describe here for the first time a critical role for miR-424 in the re

39 hod that allowed us to identify and quantify for the first time a dipeptide S-conjugate to 3MH, the g

40 d experimental study, presented here, allows for the first time a genus-wide view of the biological d

41 Here, we present for the first time a metabolomics approach based on liqu

42 These results identify for the first time a pivotal role for Arg-dependent poly

43 Here we demonstrate for the first time a room-temperature laser operation in

44 Herein, we report for the first time a series of novel, potent, and select

45 In this pilot study, the authors use for the first time a systems biology approach to compreh

46 expansion and bioorthogonal labeling provide for the first time a way for direct, site-specific label

47 lling with a variety of particle types (>4), for the first-time a particle track structure model of t

48 Herein, we demonstrate, for the first time, a backbone-degradable polymer direct

49 KEY MESSAGE: For the first time, a comprehensive proteome analysis wa

50 Our data report, for the first time, a distinctive role for peripheral TN

51 We report, for the first time, a nerve terminal impairment in SV tr

52 Hereto, for the first time, a polymeric (13)C lignin was used as

53 For the first time, a self-assembled monolayer (SAM) der

54 Within this framework, and for the first time, a study was performed to compare cou

55 We report, for the first time, aberrantly expressed lncRNAs in MDS

56 The model allows, for the first time, accurately determining the tip-sampl

57 In this paper, for the first time an InGaP (GaInP) photon counting X-ra

58 nerative diseases, these studies illustrate, for the first time, an insidious aspect of mitochondrial

59 This study for the first time analyzed the effect of decreased PPi

60 t of tissue fouling on CNT yarns was studied for the first time, and the relatively hydrophilic surfa

61 n the relaxation dynamics of dCyd and 5mdCyd for the first time, and two complementary quantum mechan

62 in processes involved in (simulated) smoking for the first time, and validate a novel approach to the

63 This adsorbent was used for the first time as an adsorbent for the vortex assist

64 t trifluoromethylstyrenes have been employed for the first time as dipolarophiles in a 1,3-dipolar in

65 to 68% of the hits are chemotypes described for the first time as late-stage gametocyte-targeting mo

66 ned in the purees, of which 19 were detected for the first time as papaya constituents.

67 iological molecule with inherent properties, for the first time, as the redox probe in the developmen

68 onwide registers on all women who gave birth for the first time between January 1, 1993, and December

69 Here, we estimate for the first time both bycatch mortality rates and thei

70 y pure amino acids, we were able to control, for the first time, both the helicity of the helix and t

71 tain absolute configuration, was synthesized for the first time by a one-pot Knoevenagel-IMDA reactio

72 plasmon-driven electron transfer is provided for the first time by direct detection of the 4,4'-bipyr

73 amines, with a useful scope, is demonstrated for the first time by use of this catalyst, and is compe

74 enzylated indoles and H2O that is catalyzed, for the first time, by a complex of earth-abundant iron.

75 For the first time, caffeic acid esters of isocitric and

76 in silico structure-based-drug-design (SBDD) for the first time, characterising inhibitors that block

77 d forms of araticum pulp, peel and seed were for the first time characterized and quantified using HP

78 For the first time, chimpanzees have been observed using

79 tides that were palmitoylated, demonstrating for the first time co-identification of these modificati

80 nsive nanomedicine (l-Arg-HMON-GOx) has been for the first time constructed for synergistic cancer st

81 urate masses of some compounds here reported for the first time corresponded to those of compounds pr

82 tivity of nitrogen Lewis acids, we prepared, for the first time, cyclic triazanes, a class of cyclic

83 e study strong-field molecular alignment in, for the first time, degenerated channels following the s

84 Here we for the first time demonstrate this extreme localization

85 fies a novel human protein disaggregase and, for the first time, demonstrates its capacity to dissolv

86 This study, for the first time, demonstrates that the stoichiometry

87 Our platform, for the first time, demonstrates the detection of hybrid

88 omultivalent glycooligomers on solid support for the first time, demonstrating the utility of this ap

89 Lambda values of 1,2-DCA were, for the first time, determined in two field sites under

90 The approach allows for the first time direct integration of high-resolution

91 Together, we provide, for the first time, evidence for epigenetic regulation o

92 synchrotron X-ray diffraction technique, we for the first time, experimentally revealed the phase tr

93 c aerosol (SOA) yields has been investigated for the first time for the photooxidation of n-dodecane

94 cer cells to cisplatin-induced apoptosis, we for the first time found that knockdown of Akt1 and the

95 dy, we report strong observational evidence, for the first time from long-term (1984-2014) spatially

96 Here, we test for the first time how early-life stress drives developm

97 he present work is important because we show for the first time how this interplay operates both with

98 This study investigates for the first time hydrogen isotope fractionation during

99 This study reports, for the first time, implementation of synchrotron-based

100 romoacetamide) was quantitatively determined for the first time in 11 real tap water samples.

101 d spatially offset Raman spectroscopy (SORS) for the first time in a food or beverage product, and de

102 17 previously reported classes were observed for the first time in AFFF and/or AFFF-impacted groundwa

103 7-O-glucuronide 3-O-glucoside was identified for the first time in artichoke.

104 Shinohara et al. have succeeded for the first time in creating transchromosomic mice by

105 verse tunnel magnetocapacitance (TMC) effect for the first time in Fe/AlOx/Fe3O4 magnetic tunnel junc

106 Biomarkers of exposure to PFRs were measured for the first time in influent wastewater.

107 -Au-S)3 "paw-like" surface motif is observed for the first time in nanocluster structures.

108 wo isolates of genotype I were also detected for the first time in Rio de Janeiro.

109 Recently, we reported for the first time in silico evidence of RIP encoding ge

110 11:3-FTB, 7:1:2 FTB and 9:1:2 FTB), observed for the first time in situ.

111 In 2015, ergot was identified for the first time in sorghum fields in Israel, leading

112 Reported for the first time in southwestern Atlantic cetaceans an

113 ntative maceration and ageing time, reported for the first time in sparkling wines.

114 We show corelease of GABA and glycine for the first time in the central nucleus of the inferio

115 ate, 1,4,5,8-naphthalenetetrone, is reported for the first time in the context of cellulose discolora

116 cy, precision and uncertainty were estimated for the first time in the kinetic and spectrometric tech

117 electrochemical cytosensor was demonstrated for the first time in this study.

118 t the subventricular zone niche and results, for the first time, in NPC migration into the stroke sit

119 icrobes was supported by arxA mRNA detection for the first time, in red-pigmented microbial mats with

120 For the first time, it is reported that dimsyl anion, fo

121 ed with rat Schwann cells, and have produced for the first time long-term and stable myelinating co-c

122 For the first time membrane components required for LFA

123 nd by X-ray photoelectron spectroscopy (XPS) for the first time; MoB2 and beta-MoB show excellent act

124 men in the U.S. EPA MAMA Study are presented for the first time; modeled predictions of milk PBDE con

125 For the first time, neurons with distance-invariant iden

126 The direct observation for the first time of a heavy-tail emissions distributio

127 In the present study, we report for the first time on the measurement and speciation of

128 Here, we report, for the first time, on regions within the 530 bp that ar

129 Especially, for the first time our results indicated the exogenous G

130 This national registry study demonstrates for the first time poorer waitlist and postliver transpl

131 controlling the PSC growth, we were able to, for the first time, precisely tune both the size and wid

132 Our studies thus for the first time provide complementary gain- and loss-

133 This work for the first time provides the structural basis for the

134 Overall, this review-for the first time-provides a comprehensive overview of

135 vice-based population activity patterns have for the first time quantified the high degree of intrada

136 This work, for the first time, reports a remarkably facile and effe

137 re detected in the Chinese cattle population for the first time, representing the unique genomic reso

138 For the first time Rutin (RU) as a biological molecule w

139 We identify, for the first time, S-loop phosphorylation as a novel, c

140 In the proposed study, for the first time, sensitive electrochemical detection

141 Our results for the first time show that CLIC-like proteins exist in

142 For the first time, significantly elevated proline level

143 For the first time, strainable high-frequency RF GaN dev

144 This study provides for the first time substantial evidence for extensive Cu

145 The SEEG Assistant Framework for the first time supports physicists by providing a se

146 search; we comprehensively review this topic for the first time, synthesizing past results and defini

147 knowledge, five polyphenolic compounds were for the first time tentatively identified in paprika: 5-

148 Here we demonstrate for the first time that a microRNA component of this reg

149 Here we show for the first time that a photon detector is capable of

150 Here we show for the first time that a portable, random-access platfo

151 The findings reveal for the first time that accumulation and in situ activat

152 pulations of Anolis sagrei lizards, we found for the first time that anoles vary consistently in thei

153 t of our knowledge, these findings highlight for the first time that arginase of all Helicobacter gas

154 Our study provided evidence for the first time that baicalein attenuated TNBS-induce

155 We show for the first time that both eIF2alphaP and ATF4 are nec

156 pot-producing magnetic fields and discovered for the first time that bursty and quiet seasons, manife

157 Our study in the Great Barrier Reef confirms for the first time that dugongs (Dugong dugon) and green

158 We demonstrate for the first time that efferent-mediated slow excitatio

159 These data demonstrate for the first time that etoposide- and cisplatin-induced

160 This work demonstrates for the first time that experimental conditions optimize

161 This work describes for the first time that FLA carrying M. bovis can transm

162 It is shown for the first time that gray matter density increases fr

163 Here we demonstrate for the first time that harmonic nanomechanical resonato

164 Furthermore, we showed for the first time that HVEM-specific HSV-1 neutralizing

165 Mechanistically, we show for the first time that IL10 suppresses Smad-miRNA-21-me

166 Here, we show for the first time that inhibitory RGMa is markedly upre

167 ts comparison with MMS observations, we show for the first time that ion-scale jets from vortex-induc

168 This study showed for the first time that LCCPs from C18 to C36, as well a

169 These results demonstrate for the first time that local mRNA sequence context play

170 Results indicated for the first time that luminescence switchable CNPs can

171 Importantly, we show for the first time that M. bovis arrests phagosome matur

172 Using 2D NMR spectroscopy, we established for the first time that MK-2 has a folded conformation d

173 Here, we show for the first time that NCX1 mRNA and protein expression

174 Here we show for the first time that overexpression or knockdown of R

175 In conclusion, we demonstrated for the first time that P. australis degrades IBP from w

176 Our simulated and experimental data reveal for the first time that positioning particles in three-d

177 To our knowledge, this study shows for the first time that PRIT with TF2 and (213)Bi-IMP288

178 Thus, our data indicate for the first time that RAGE inhibition has an essential

179 We show for the first time that raspberry metabolites present in

180 Here we demonstrate for the first time that squamous cell carcinoma (SCC) EV

181 We show here for the first time that TGFbeta can induce purified prim

182 In this work, it is shown for the first time that that direct-write e-beam exposur

183 In this work, it was shown for the first time that the combination of a propidium m

184 Finally, we are able to establish for the first time that the current state-of-the-art ion

185 We demonstrate for the first time that the design of an optofluidic wav

186 These results show for the first time that the enzymatic activity of HDAC3

187 ns with pathological hallmarks Here, we show for the first time that the extent of early hippocampal

188 interfacial termination, it is demonstrated for the first time that the FE critical thickness can re

189 ytical instruments, we present in this study for the first time that the generation of 2-ACBs was als

190 To our knowledge, these data show for the first time that the mechanoreceptor ICAM-1 is ne

191 We have demonstrated for the first time that the mitochondria-based piezosens

192 Here, we report for the first time that the oxygen reduction activity of

193 In this study, we report for the first time that the primary cilium acts as a cru

194 In the present study, we show for the first time that the RSC and ACA contain neurons

195 To address this challenge, we report for the first time that the Winstein rearrangement can b

196 TES for treatment of epilepsy, we show here for the first time that unsupervised closed-loop TES in

197 These data show for the first time that varenicline reduces relapse trig

198 These results show for the first time that, during exposure to an HIV-1 neu

199 NOD-scid IL-2Rgammanull mice to demonstrate for the first time that: i) mouse and human MAIT cells a

200 We demonstrate, for the first time, that a functional reorganization cha

201 Here we show for the first time, that a mutation that prolongs the st

202 We show, for the first time, that a unified description is possib

203 Collectively, we have demonstrated, for the first time, that BUP, NBUP, and MET are potent A

204 We show, for the first time, that dopamine axons continue to grow

205 Thus, our results reveal, to our knowledge for the first time, that IL-3 differentially regulates t

206 Here we show, for the first time, that modulations of brain oscillatio

207 yunsaturated omega-3 and omega-6 lipids and, for the first time, that of vitamin A, naturally present

208 The present study revealed, for the first time, that Rodentia associated UMRV emerge

209 We report, for the first time, that the excitation of a peripheral

210 We find, for the first time, that the model thalamic network is c

211 Here we demonstrate, for the first time, that transient administration of the

212 Our results reveal for the first time the dynamic connection between FTO RN

213 This study demonstrates for the first time the efficacy of the HMP Airdrive syst

214 ment of botanical drugs, while demonstrating for the first time the feasibility of microfluidics in t

215 esponse of these materials, we have observed for the first time the formation of a charge transfer st

216 onic acid and a tetraazanaphthacene provided for the first time the formation of a supramolecular H-b

217 Especially, for the first time the fully tunable conductivity of ReS

218 We report for the first time the high sorption properties of a mol

219 ery Large Database of Lipids study to assess for the first time the impact of fasting status on novel

220 Here, we investigate for the first time the influence of macroscale and nanos

221 This study shows for the first time the involvement of TLRs expressed on

222 Our study describes for the first time the molecular effects of different re

223 on of mice with HSV-1, we have characterized for the first time the neuroimmune-glia interactions in

224 Interestingly, we also report for the first time the occurrence of pipecolic acid beta

225 We report for the first time the physiological changes of algal ce

226 We have explored for the first time the possibility to achieve similar pe

227 In the present study, we describe for the first time the presence of ACSL6 mRNA in human s

228 This method allows for the first time the rapid detection, differentiation,

229 bisphosphine/K3PO4 catalytic system allowing for the first time the selective branched C-H alkylation

230 Here, we test for the first time the spatiotemporal dynamics of these

231 We report here for the first time the temperature dependences of LSSE v

232 We have established for the first time the total phenolic compounds and tota

233 We recorded and quantitatively modeled for the first time the transient response of the catalyt

234 In this study, we demonstrate for the first time the use of a novel design approach of

235 We report for the first time the use of hexavalent chromium (Cr(VI

236 Here, we report for the first time the use of Zincke reaction to fabrica

237 This breakthrough ensures, for the first time, the applicability of advanced FWI me

238 psulating radiolabeled cancer cells allowed, for the first time, the detection of [(18)F]FDG radiotra

239 e used protein semisynthesis to investigate, for the first time, the effect of lysine acetylation and

240 For the first time, the electrospray ionization efficien

241 This study reveals, for the first time, the extensive human protein interact

242 This method enables, for the first time, the full spectrum of transcriptome d

243 Here we characterize, for the first time, the functions of PPP1R1A in Ewing sa

244 For the first time, the growth kinetics of CaCO3 under m

245 This work shows for the first time, the impact of wine composition on or

246 r to address this issue, our paper presents, for the first time, the integration on a single glass su

247 rmore, single-particle EM analysis revealed, for the first time, the overall architecture of the MCM-

248 For the first time, the stereospecific strain-release "c

249 For the first time, the successful collapse of polymeric

250 Our results demonstrate, for the first time, the transcriptional up-regulation of

251 We demonstrate, for the first time, the use of this powerful new tool in

252 For the first time, the utility and performance of such

253 For the first time, this study reports a ddHRMS/MS metho

254 ather reports from over 500 manned stations, for the first time, this study shows a significant decre

255 was assessed through growth experiments and, for the first time, through vitality measurements.

256 Here we apply thermal desorption PTR-MS for the first time to characterise the chemical composit

257 The aim of this prospective study was for the first time to compare the D816V status of the "s

258 abel-free fluorescence spectroscopy was used for the first time to determine spectral profiles of try

259 combines RI tomography and machine learning for the first time to our knowledge, could be a versatil

260 This study investigates-for the first time to our knowledge-the existence and me

261 tic molecular dynamics simulations, are used for the first time to reconstruct the air-liquid crystal

262 This allowed us, for the first time, to assess the contributions of multi

263 r's disease susceptibility allele was found, for the first time, to be a loss of function allele.

264 ed with MALDI-MS allowed these two epitopes, for the first time, to be directly identified on the pol

265 elling techniques in zebrafish we were able, for the first time, to dynamically track cell behaviours

266 ination of these new technologies allows us, for the first time, to map the physical 3D structure of

267 Our results show for the first time, to our knowledge, an important role

268 We report for the first time, to our knowledge, an inverse associa

269 We also show for the first time, to our knowledge, that lipin-1 knock

270 Overall, our findings demonstrate for the first time, to our knowledge, that T cell-derive

271 great ape, orang-utans (Pongo pygmaeus), and for the first time, to our knowledge, the external appli

272 In this study, we explored for the first time, to our knowledge, the role of PIKfyv

273 For the first time, to our knowledge, we show that rfhSP

274 nzymatic methodology that makes it possible, for the first time, to prepare any bi-, tri-, and tetra-

275 researchers to directly image and quantify, for the first time, translation initiation and elongatio

276 For the first time, trapped ion mobility spectrometry (T

277 Here we report for the first time, using a combined molecular dynamics

278 For the first time, variations in miscanthus cell wall g

279 tances in animal feed entered into force and for the first time was laid down a maximum limit for nit

280 Here using P. yoelii, for the first time we provide a proteomic comparison of

281 Based on ME property, for the first time we show that MENs can distinguish dif

282 Here, for the first time, we experimentally demonstrate the de

283 For the first time, we found that TTPA also exhibits lyt

284 Furthermore, for the first time, we have shown that SR Ca content is

285 Here, for the first time, we introduce the true multiorbital c

286 Here, for the first time, we investigate the treatment efficie

287 Herein, for the first time, we propose a biomimetic biosensor fo

288 Herein, for the first time, we report a family of sodium-ion bat

289 Here, for the first time, we report carious lesions preserved

290 Furthermore, for the first time, we report epitaxial growth in aqueou

291 Here, for the first time, we show robust evidence of a decreas

292 Also, for the first time, we show that an integrated two compa

293 For the first time, we show that loss of FLG in the abse

294 arrived at an experimentally provided feeder for the first time were compared with experienced ants t

295 Our aim was to test, for the first time, whether the nephrosphere (NS) cells,

296 In a subsequent retest we asked, for the first time, whether young children increase thei

297 One jet had an unusual form observed for the first time, which emerged from the leading edge

298 and CsSnI3 perovskites is studied carefully for the first time, which has led to the realization of

299 lasma mass-spectrometry (SP-ICP-MS) was used for the first time with a prototype data acquisition (mu

300 motifs are accessed in enantioenriched form for the first time with high levels of stereocontrol, an