1 G15 protein and its conjugated proteins upon
forced expression.
2 Among them, Sox9 has unique capacity: its
forced expression accelerates differentiation of mouse E
3 Through
forced expression and knockdown of Cten in HCT116 and SW
4 Moreover,
forced expression and knockdown of SPZ1 in hepatoma cell
5 atial restriction and the ability to sustain
forced expression are important advantages over the curr
6 well as in inducing ectopic eye formation in
forced expression assays.
7 Knockdown and
forced expression experiments identified the receptor un
8 We probed, in
forced expression experiments, the capacity of PHOX2A to
9 CiaR, as a result of either ciaH deletion or
forced expression from a constitutive promoter, is a med
10 FOXP3 is exclusively expressed in Tregs and
forced expression in CD4(+)CD25(-) T cells can convert t
11 2(R65Q/W) in patient-derived lymphocytes and
forced expression in control CTLs and NK cells diminishe
12 ants disrupted periderm differentiation upon
forced expression in zebrafish embryos, suggesting that
13 pigenetically silenced in TOSE cells and its
forced expression increased TOSE colony size.
14 ture conditions, lentivirus-mediated miR-503-
forced expression inhibited EC proliferation, migration,
15 he nucleus of intestinal stem cells, and its
forced expression leads to enhanced Wnt signalling in cr
16 ASP2-interaction partner LL5beta by RNAi and
forced expression of a CLASP2 fragment blocking the CLAS
17 We recently observed that
forced expression of a combination of three transcriptio
18 acrophages with chemical AMPK activators, or
forced expression of a constitutively active form of AMP
19 ation of cleft palate and ectopic cartilage,
forced expression of a constitutively active form of BMP
20 Conversely,
forced expression of a constitutively active form of Yap
21 This is rescued by
forced expression of a deacetylated CTTN mimetic.
22 ession in CP-CML, we examined the effects of
forced expression of a dominant-negative isoform of IKAR
23 rentiation and loss of self-renewal, whereas
forced expression of a polycistron construct encoding mi
24 We also show that
forced expression of a second oncogene in human cancer c
25 00% yield and purity in less than 2 weeks by
forced expression of a single transcription factor.
26 Forced expression of a transgenic BCR or a BclxL transge
27 Moreover,
forced expression of A1 in CD8 T cells from OX40-deficie
28 canonical Wnt signaling introduced either by
forced expression of activated beta-catenin, or the smal
29 ssion of the transcription factor lhx1a, and
forced expression of activated forms of the lhx1a gene p
30 Moreover,
forced expression of activated NOTCH3 increased MSI-1 le
31 Furthermore,
forced expression of Adrx decreased TNFalpha-induced act
32 Forced expression of Agr2 is sufficient to promote the g
33 AIPL-1 is expressed in embryonic muscle, and
forced expression of AIPL-1 in adult muscle compensated
34 Forced expression of Amigo2 in QRsP-11 cells increased l
35 role of CREBH in lipogenesis and lipolysis,
forced expression of an activated form of CREBH protein
36 Reciprocally,
forced expression of ARID1B inhibits Wnt/beta-catenin si
37 the survival and growth of T-ALL cells, and
forced expression of ARID5B in immature thymocytes resul
38 Forced expression of ARTN also dramatically enhanced tum
39 Forced expression of ASB2 degrades MLL and reduces MLL t
40 not expressed in mammalian MG after injury,
forced expression of Ascl1 in mouse MG induces a neuroge
41 We now test whether
forced expression of Ascl1 in mouse Muller glia in vivo
42 We previously reported that
forced expression of Ascl1 in vitro reprograms Muller gl
43 Here, we reveal that
forced expression of ATF3 in motor neurons of transgenic
44 Forced expression of ATF4 and CHOP protein before UVB ir
45 However,
forced expression of ATF4 and its target gene CHOP leads
46 Furthermore,
forced expression of Atf4 in chondrocytes induces endoge
47 Although
forced expression of Bak markedly sensitizes toward p14(
48 Conversely,
forced expression of Bam in the lymph gland results in e
49 n experimental autoimmune encephalomyelitis,
forced expression of BCL6 in myelin oligodendrocyte glyc
50 ly downregulated in polarized Th9 cells, and
forced expression of BCL6 in Th9 cells impairs Th9 cell
51 after degenerative loss, could be driven by
forced expression of beta-catenin to act as hair cell pr
52 These effects are attenuated by
forced expression of Bmi-1, suggesting that PcG proteins
53 In contrast,
forced expression of Bnc1 modifies plasma membrane/cytos
54 Forced expression of bta-miR-23a mimics reduced lipid ac
55 Forced expression of c-myc in RGCs, either before or aft
56 ate DNA synthesis that occurs as a result of
forced expression of c-myc leads to the activation of th
57 Consistently,
forced expression of C/EBP-delta increased VEGF-C and VE
58 fibroblasts toward a myocardial cell fate by
forced expression of cardiac transcription factors or mi
59 be reprogrammed to cardiac-like myocytes by
forced expression of cardiac transcription factors with
60 amming of fibroblasts into cardiomyocytes by
forced expression of cardiomyogenic factors, GMT (GATA4,
61 els of the T-cell receptor-CD3zeta chain and
forced expression of CD3zeta into SLE T cells restores I
62 Forced expression of CD69, a negative regulator of S1P1
63 Forced expression of Cdc25B inappropriately up-regulated
64 We found that
forced expression of Cdk6 promotes continued cell divisi
65 However,
forced expression of CDX1 in HCT116 leads to reduced clo
66 Differentiation can be facilitated by
forced expression of certain transcription factors (TFs)
67 By
forced expression of constitutively active or dominant-n
68 in a decrease in Creb1 and Pknox1 mRNA, and
forced expression of CREB1 in Hoxa9(-/-) bone marrow cel
69 However, inhibition of ILK after
forced expression of Cten abrogated the motility-inducin
70 Forced expression of Cxcl12, Fzd2, or Ifi27l2a increases
71 Forced expression of CXCL14 in H23 cells, where this gen
72 Forced expression of Cyclin B partially restored the G1
73 Conversely,
forced expression of Dally causes ectopic accumulation o
74 nduced pluripotent stem cells (iPSCs) by the
forced expression of defined transcription factors in so
75 Forced expression of defined transcriptional factors has
76 In particular,
forced expression of diacylglycerol kinase beta abrogate
77 Forced expression of dma-1 in neurons with simple dendri
78 is blunted by the knockdown of Rac or by the
forced expression of dominant-negative Rac.
79 ld not be recovered by T-cell activation, by
forced expression of E2A or by the up-regulation of this
80 are two direct target genes of miR-495, and
forced expression of either of them can reverse the effe
81 Forced expression of embryonic dystrophin in zebrafish u
82 Importantly,
forced expression of Eomes partly protected TCF-1-defici
83 expression, migration and invasion, whereas
forced expression of EpCAM resulted in decreased ERK pat
84 Forced expression of EphA4 reversed the effects of miR-5
85 Forced expression of ERbeta1 promoted growth suppression
86 Forced expression of ERG in prostate tumor cell lines re
87 Conversely,
forced expression of Esg in intestinal progenitor cells
88 thelial regulator of splicing 1 (ESRP1), and
forced expression of ESRP1 in invasive mesenchymal breas
89 We further demonstrate that
forced expression of ESRP2 in immature mouse and human h
90 Here we show that
forced expression of FGFR3b-S249C, the most prevalent FG
91 Moreover,
forced expression of forkhead box protein O1 (FoxO1), an
92 ilia found elsewhere in the neural tube, and
forced expression of Foxj1 in neuroepithelial cells is s
93 Forced expression of FOXO1 also inhibited Runx2-promoted
94 Conversely,
forced expression of FOXO1 restricts vascular expansion
95 ion by Ikaros-mutant CD4(+) T cells, whereas
forced expression of Foxp3 was sufficient to inhibit thi
96 Forced expression of fragments expressing the antisense
97 Forced expression of full-length SHIP significantly redu
98 nge; these responses could be rescued by the
forced expression of full-length SSeCKS but not by an SS
99 Conversely,
forced expression of Gadd45a in muscle or cultured myotu
100 We found that, despite
forced expression of GARP on all T cells, stimulation th
101 We found that
forced expression of GAS5 blocked, but knockdown of GAS5
102 ely, administration of BMP signals to PSM or
forced expression of GATA family members in chick PSM ex
103 reduced glucose uptake that was reversed by
forced expression of Glut1.
104 Forced expression of GPR56 results in myotube hypertroph
105 f prostate cancer xenografts in SCID mice by
forced expression of GPx3 suggests a tumor suppression r
106 a direct phosphorylation by MAP kinases, and
forced expression of GRD does not suppress the effect of
107 Forced expression of HDAC3 also promotes the death of ra
108 Forced expression of HDAC3 induces death of otherwise he
109 Forced expression of HDAC7 in cultured CGNs blocks low p
110 Conversely,
forced expression of Helios in CD4(+)Foxp3(-) T cells re
111 Conversely,
forced expression of HMGA1 blocks differentiation of hES
112 Forced expression of Hmga2 resulted in increased chimeri
113 Conversely,
forced expression of Hoxa9 increased Flt3 transcription
114 In addition,
forced expression of HPIP in K562 cells, a multipotent e
115 Forced expression of HRT2 demonstrated simultaneous repr
116 Forced expression of hsa-miR-125b in these cells resulte
117 Forced expression of hsa-miR-17* mimic and hsa-miR-30c i
118 4KO) in a lupus-like disease model driven by
forced expression of HSP gp96 at the cell surface (trans
119 We then use lentivirus-mediated
forced expression of human ETS2 to convert normal human
120 In this study, we show that
forced expression of human TGF-beta(1) gene by retroviru
121 actions was restricted to myogenic cells, as
forced expression of ICAM-1 by fibroblasts did not augme
122 down-regulated in CIA mouse ankles receiving
forced expression of IL-27.
123 Forced expression of inhibitory Smads, including Smad6 a
124 The
forced expression of insulin/IGF-like peptides in glia,
125 Our analysis revealed that
forced expression of Irf4 repressed ES-DC development, w
126 Strikingly,
forced expression of isoform 5, which encodes only a 20-
127 Blockade of Egr-1 via
forced expression of its dominant-negative mutant attenu
128 nective tissue growth factor (CTGF), whereas
forced expression of Jun~FosB stimulated TNC and CTGF pr
129 Forced expression of KDM2B promotes immortalization by s
130 uripotent stem cell (iPSC) state through the
forced expression of key transcription factors, and in t
131 r transdifferentiation) usually requires the
forced expression of key transcription factors.
132 Forced expression of Kir2.1 in hESC-CMs led to robust ex
133 On the other hand,
forced expression of KLF14 leads to mitotic catastrophe.
134 Furthermore,
forced expression of KLF4 in the highly metastatic MDA-M
135 Knockdown of Klf5 or
forced expression of Klf4 inhibited stiff matrix-induced
136 Forced expression of LEF-1 enhanced T(FH) differentiatio
137 Forced expression of LIGHT also results in the expansion
138 Our data show that
forced expression of LIGHT in tumors results in an incre
139 Further,
forced expression of lin-42a leads to anachronistic larv
140 Forced expression of Lin28B in embryonic mouse sympathoa
141 ly reprogrammed into a distinct cell type by
forced expression of lineage-determining factors.
142 oma cells with high LMO1 expression, whereas
forced expression of LMO1 in neuroblastoma cells with lo
143 Furthermore,
forced expression of LNK reduced cell size, inhibited ce
144 uid and may be altered experimentally by the
forced expression of master regulators mediating cell li
145 Direct reprogramming can be achieved by
forced expression of master transcription factors.
146 Forced expression of MAT1A induced genes related to apop
147 Forced expression of MAT2A in RSG-treated HSCs lowered P
148 Forced expression of Mcl-1 blocked mda-7/IL-24 lethality
149 Forced expression of MCM8 in RWPE1 cells, the immortaliz
150 Treatment of 3T3-L1 cells with MCP-1 or
forced expression of MCPIP induces expression of C/EBPbe
151 Forced expression of MCPIP induces expression of the C/E
152 constitutively expressed in cancer cells and
forced expression of mda-7/IL-24 (Ad.mda-7) or SARI (Ad.
153 Forced expression of MeCP2-e2, but not MeCP2-e1, promote
154 s (iCPCs) from mouse adult fibroblasts using
forced expression of Mesp1, Tbx5, Gata4, Nkx2.5 and Baf6
155 mellitus, with this effect being reversed by
forced expression of microRNA-155.
156 'missing-self' response can be prevented by
forced expression of minimally polymorphic HLA-E molecul
157 inhibited EMT during tumorigenesis, whereas
forced expression of miR-1 or miR-200 inhibited both EMT
158 Forced expression of miR-125a resulted in elevated cellu
159 Cgi58, activators of lipolytic activity, and
forced expression of miR-145 attenuates lipolysis.
160 and represses Prdm16 and Ppargc1a, and that
forced expression of miR-150 attenuates the elevated exp
161 Forced expression of miR-150 dramatically inhibited leuk
162 cy in mice results in mild vascular defects,
forced expression of miR-155 causes endothelial hyperpla
163 Forced expression of miR-16 inhibited in vitro prolifera
164 Forced expression of miR-194 in breast cancer cells that
165 Luciferase assays demonstrated that
forced expression of miR-196b inhibited the FOS promoter
166 Forced expression of miR-196b significantly delays MLL-f
167 However,
forced expression of miR-21 rescued osteoclast developme
168 Forced expression of miR-210 was found to suppress the l
169 ively regulated after T cell activation, and
forced expression of miR-214 in T cells led to increased
170 Finally,
forced expression of miR-214-3p enhances the sensitivity
171 Forced expression of miR-214-3p in esophageal cancer cel
172 Forced expression of miR-22 significantly suppresses leu
173 Forced expression of miR-23b cluster or miR-125a-5p enha
174 Indeed,
forced expression of miR-29c strongly induced podocyte a
175 ctor in homology-dependent repair (HDR); the
forced expression of miR-373 led to a reduction in the n
176 Forced expression of miR-486-5p inhibited NSCLC cell mig
177 marrow transplantation studies, we show that
forced expression of miR-495 significantly inhibits MLL-
178 Furthermore,
forced expression of miR-9 can significantly promote MLL
179 NA sponge can significantly inhibit, whereas
forced expression of miR-9 can significantly promote, ML
180 We showed that
forced expression of miR-93 in cells abrogated VEGF prot
181 Forced expression of miR-98 in T cells resulted in suppr
182 sed with Onconase treatment, as well as with
forced expression of miRNA mimic and inhibitors.
183 Vector-based
forced expression of miRNA-768-3p complementary sequence
184 Furthermore,
forced expression of miRs diminished GCLC and GSR expres
185 Forced expression of MIST1 in PCs caused them to expand
186 In contrast,
forced expression of MITF in melanoma and colon cancer c
187 In murine models,
forced expression of MN1 in hematopoietic progenitors in
188 Forced expression of MN1 in primitive mouse hematopoieti
189 Here, we show that
forced expression of MRTF-A in dermal fibroblasts stimul
190 Forced expression of MRTF-A precisely emulates the anti-
191 Forced expression of Msgn1 in NM stem cells in vivo redu
192 hese genes, Myc, is neuroprotective, whereas
forced expression of Myc induces Rattus norvegicus neuro
193 Forced expression of MYOCD increased Kcnmb1 expression i
194 tiation of primary human skin fibroblasts by
forced expression of myogenic transcription factor MyoD,
195 Conversely,
forced expression of myogenin in skeletal muscle of HDAC
196 Remarkably,
forced expression of myomaker in fibroblasts promotes fu
197 Forced expression of NANOG in epiblast stem cells is suf
198 Forced expression of necdin enhances mitochondrial funct
199 equired for normal lethargus quiescence, and
forced expression of nlp-22 during active stages causes
200 Forced expression of nonfunctional SVs conferred a survi
201 Accordingly,
forced expression of Numbl abrogated osteoclastogenesis
202 Forced expression of NUMBL inhibits osteoclast different
203 'Nurr1' here), inducing transcription, while
forced expression of Nurr1 reversed the loss of quiescen
204 NDRs can be restored by
forced expression of OCT4 in somatic cells but only when
205 erivation without the use of transgenes, and
forced expression of OCT4, KLF4, and KLF2 allows mainten
206 The stable
forced expression of Oct4A in normal human urothelial ce
207 We found that
forced expression of OPN in early vertical-growth-phase
208 rotein rapsyn in an isoform-specific manner;
forced expression of P1f in plectin-deficient cells resc
209 ed as cells differentiate into STB, and that
forced expression of p63 maintains cyclin B1 and inhibit
210 mogenesis; such effects could be reversed by
forced expression of PBX3.
211 1A2 gene, which could not be reversed by the
forced expression of PCAF or PKC delta.
212 Similarly, silencing of miR-21 or STAT3 and
forced expression of PDCD4 in arsenic transformed cells
213 Finally, cold, beta-agonists, or
forced expression of PGC-1alpha are unable to cause ther
214 Paradoxically,
forced expression of PGC-1alpha in muscle promotes diet-
215 Forced expression of PHF8 resensitizes ATRA-resistant AP
216 Focal cAMP reduction was achieved by
forced expression of phosphodiesterase 4A1 (PDE4A1) in t
217 Forced expression of PIP2-binding-deficient mutants of v
218 Forced expression of plakoglobin in SLUG-high cells had
219 al analysis of transgenic mouse T cells with
forced expression of PLZF.
220 ltanonA strains lack sialidase activity, but
forced expression of pneumococcal NanA in GBS induced de
221 However,
forced expression of pneumococcal NanA in GBS removed te
222 Forced expression of POPDC1(S201F) in a murine cardiac m
223 Forced expression of PPARgamma enhanced the sensitivity
224 ich is reversed by the addition of NAC or by
forced expression of PRDX6, suggesting that Fkbp52 defic
225 Interestingly,
forced expression of prearranged TCR but not IL-7Ralpha
226 Forced expression of putative interneuron markers Dmbx a
227 Forced expression of recombinant afadin in pulmonary end
228 Forced expression of RORgammat successfully rescued TCF-
229 The epigenetically
forced expression of Runx2/p57 and osteocalcin, a classi
230 Forced expression of S1P1 prevented the establishment of
231 Forced expression of SAP in SLE T cells normalized IL-2
232 Forced expression of SARI using an adenovirus (Ad.SARI)
233 Forced expression of Semaphorin-7a in ERF-overexpressing
234 eversed the effects of miR-219 depletion and
forced expression of Shh phenocopied miR-219 deficiency.
235 an T cell reactivity can be downmodulated by
forced expression of Siglec-5.
236 We found that
forced expression of SIRT1 in non-transformed PZ-HPV-7 p
237 Forced expression of Six1 in the postnatal retina was su
238 ivity of normal mammary stem cells, and that
forced expression of Slug in collaboration with Sox9 in
239 Forced expression of SMAD7 in beta cells by itself was s
240 Remarkably,
forced expression of Sox factors, in combination with ot
241 In contrast,
forced expression of Sox17 down-regulates ES cell-associ
242 We also show that stable
forced expression of SPDEF results in increased expressi
243 s or a hepatocyte cell line upregulates, but
forced expression of SRA inhibits ATGL expression and fr
244 Forced expression of Stat3 significantly increased Th17
245 Forced expression of STIM1 in cultured adult feline vent
246 d with IFN-gamma and lipopolysaccharide, and
forced expression of T-bet in these cells rescued IgG2a
247 Consistently, it was inhibited by
forced expression of T-bet or RORC2, the lineage-definin
248 Forced expression of TCF-1 in bone marrow progenitors pa
249 non-adipogenic fibroblasts, and, remarkably,
forced expression of TCF7L1 is sufficient to commit non-
250 LIF/Stat3- and 2i-mediated self-renewal, and
forced expression of Tfcp2l1 can recapitulate the self-r
251 Forced expression of TG1 or TG2 proteins is sufficient t
252 on and expression of ECM that are rescued by
forced expression of TGFbeta2.
253 In addition,
forced expression of the acinar-restricted transcription
254 Forced expression of the Bbeta subunit in primary human
255 Forced expression of the Bmi-1 polycomb protein in SCC-1
256 activation of the endogenous CA IX either by
forced expression of the dominant-negative DeltaCA varia
257 This phenotype could be rescued by the
forced expression of the GTPase-activating protein (GAP)
258 We found that IFN-gamma treatment or
forced expression of the IFN-induced GTPase, mGBP-2, inh
259 Forced expression of the mutant CD22DeltaE12 protein in
260 We found that
forced expression of the Notch inhibitor NUMB in HepaRG
261 Forced expression of the relevant Numb splice isoform wa
262 Furthermore,
forced expression of the repressor isoform of Ovol2 is a
263 of TdT expression in TdT(-/-) mice by early
forced expression of the short splice variant of TdT-res
264 Forced expression of the three transcription factors Sox
265 t stem cells (iPSCs) can be achieved through
forced expression of the transcription factors Oct4, Klf
266 Forced expression of the WT1(-KTS) isoform, which functi
267 We show that
forced expression of these exon regulatory elements coul
268 Forced expression of these factors in dividing non-cardi
269 Forced expression of these miRNAs suppressed MITF protei
270 The opposite occurred with
forced expression of these miRNAs.
271 Forced expression of these non-reprogrammed genes improv
272 Forced expression of these novel genes resulted in IL3-i
273 We further observe that
forced expression of this miRNA cluster increases prolif
274 We recently reported that
forced expression of TIMP-2, as well as the modified for
275 ssue factor gene promoter was activated, and
forced expression of tissue factor cDNA was achieved in
276 Because
forced expression of TR2/TR4 in murine adult erythroid c
277 t fibroblasts can be converted to neurons by
forced expression of transcription factors.
278 Further, the
forced expression of TRPM2 mutant channel (C1008-->A) or
279 In addition,
forced expression of tuberin in tuberin-null cells aboli
280 Forced expression of TWIST1 on the left side induced ect
281 We found that
forced expression of V3 by ASMCs affected expression of
282 Forced expression of VEGF-C, but not recombinant VEGF-C,
283 ry development and in kidney cyst formation;
forced expression of vhnf1 mRNA led to rescue of the pk1
284 Forced expression of Vsig4 in mice ameliorates MHV-3-ind
285 RNAs identified Insulin-like Receptor (InR),
forced expression of which completely rescues lin-28-ass
286 Compared with
forced expression of wild type TDG, CRL4(Cdt2)- resistan
287 Conversely,
forced expression of wild-type CtBP2 in the knockdown ce
288 Forced expression of wild-type human VEGFC in the floorp
289 Although
forced expression of wild-type p53 was not sufficient to
290 Using a combination of protein silencing and
forced expression of wild-type/constitutively active var
291 In fact, we show that
forced expression of Wip1 in premature senescent tumor c
292 e1 and Prickle2 in individual cells or local
forced expression of Wnt5a perturbed polarization of nei
293 Forced expression of WT or variant Kcnj2 changes the nor
294 on has been found in many human cancers, and
forced expression of XIAP blocks apoptosis.
295 Forced expression of Yap prolongs proliferation in the p
296 Interestingly, the
forced expression of Zscan4 is required onlyfor the firs
297 Forced-expression of MICU1 in normal cells phenocopies t
298 MHC-I-dependent immune responses or to MHC-I
forced expression per se.
299 Conversely,
forced expression phenocopied Gsk3 inhibition or Tcf3 de
300 SCLC cells treated with combination of TUSC2
forced expression with erlotinib increased tumor cell ap