ライフサイエンスコーパス: forge

1 the GPLv3 license through Bioconductor and R-Forge.

2 rically encumbered carbon-carbon bonds to be forged.

3 lly congested natural product could never be forged.

4 organic photovoltaic devices is still being forged.

5 lobionts." As such, their collective genomes forge a "hologenome," and models of animal and plant bio

6 e the experiences that led to my decision to forge a career as an academic molecular animator, and ho

7 The challenge is to forge a consensus on ethical guidelines and safeguards t

8 We conclude that lst-1 and sygl-1 forge a critical link between Notch signaling and GSC ma

9 Specifically, we forge a direct link between the PTEN-Akt-FOXO axis and t

10 These results altogether forge a framework for our deep understanding into snakes

11 from the two major existing algal groups to forge a highly successful, species-rich protist lineage.

12 which is intercepted by boryl aniline 31 to forge a new C-N bond.

13 directors), the project collaborators helped forge a new national consensus on the learning agenda fo

14 In this issue of Neuron, Misic et al. (2015) forge a promising new direction by modeling the propagat

15 tation of an intermediate dihydropyranone to forge a stereochemically defined (E,Z)-dienamide unit.

16 Its goals are to forge a strategy to accelerate the diagnosis of rare or

17 The results forge a strong link between PPIases and the transcriptio

18 air and a rare, two-turn 310 helix, together forge a substrate-binding pocket with an open clamshell

19 hibitory signaling in the autistic brain and forge a translational path between animal and human mode

20 tyrosine kinase/adaptor protein signaling to forge a unique approach for selectively killing leukemic

21 The study also forges a bridge with the face recognition literature.

22 The core scaffold of the phenolic ligand forges a hydrogen-bonding network involving the 4-hydrox

23 indicate a mechanism of PTEN regulation that forges a link between distinct cancer-relevant pathways

24 ssociates with active promoters, the finding forges a new link between transcription, epigenetics, an

25 This brainstem link forges a new understanding of the relationship between t

26 by endogenous ligand, Ro60-associated ssRNA, forges a nexus between TLR ligation and fibrosis instiga

27 implement a challenging cationic cyclization forging a bond between two sterically encumbered quatern

28 sequence generation, and spatial navigation, forging a direct link between cellular and systems neuro

29 PGC-1alpha and PGC-1beta promoters, thereby forging a direct link between telomere and mitochondrial

30 icant part of an active hammerhead ribozyme, forging a link between nonenzymatic polymerization and t

31 onstrain conformationally mobile motifs, but forging a macrocycle bond typically becomes more difficu

32 ave led to the use of PET and the ability to forge advances in the field of oncology.

33 Finally, as we forge ahead we must construct measurements of our safety

34 iatrics and pediatric cardiology continue to forge ahead with better diagnoses, medical care, and sur

35 ensates for this aversion, allowing flies to forge ahead.

36 As insight in fungal immunopathogenesis forges ahead, interventions for boosting immune function

37 Many researchers are forging ahead with projects to sequence a range of speci

38 who compete over mates, while simultaneously forging alliances between opposite-sex siblings.

39 that a vision surveillance system should be forged among federal agencies.

40 ns in flies provides a unique opportunity to forge an integrated mechanistic understanding of biochem

41 : We review recent literature with a view to forge an integrative understanding of the molecular, cel

42 tein FANCD2 by monoubiquitylation; this then forges an association with the BRCA1 protein at sites of

43 This work forges an important link between the FMR1 gene, altered

44 Professional integrity is vital in forging an ethically sound relationship between investig

45 ctive we examine how these linkages might be forged and how the new science of the mind might serve a

46 on was markedly reduced for both solid-glass forging and liquid-melt molding.

47 and enables message sending ensured against forging and repudiation.

48 between two tolerant elm varieties, 'Valley Forge' and 'Princeton,' also indicated that tolerance ag

49 Over the last decade, a clear link has been forged between Lis1 and the microtubule motor cytoplasmi

50 Robust Zr(IV)-carboxylate bonds are forged between the Zr clusters of NU-1000 and carboxylic

51 ptide (Nepsilon-Gly-L-homothiaLys) bonds are forged between two molecules of Ub, demonstrating the po

52 Their widespread use to forge bonds between two aromatic rings has enabled every

53 n contrast, we argue that mirror neurons are forged by domain-general processes of associative learni

54 eins, with the isodityrosine links primarily forged by Tyr151-Tyr151 coupling.

55 es in C-C fragment couplings, the ability to forge C-O bonds in a general fashion via nickel catalysi

56 Reactions that forge carbon-carbon (C-C) bonds are the bedrock of organ

57 lication of Suzuki-Miyaura cross-coupling to forge carbon-carbon bonds, the structure of the reactive

58 Metal-catalyzed transformations that forge carbon-heteroatom bonds are of central importance

59 ity initiative, the next steps will focus on forging collaboration with groups working on obesity-rel

60 dicine and mental health professionals might forge collaborative relationships to provide more access

61 s and provides a framework for measuring and forging collective memories in communities of individual

62 rticularly appealing when multiple rings are forged during this process.

63 ertiary azide, obviates the need to directly forge either a congested C-N or C-C bond at the new nitr

64 Such cross-disciplinary research, by forging empirical links in causal chains from risk genes

65 s have enabled semiconductor electronics and forging enabled introduction the of iron age.

66 encode information for long-term storage by forging excitatory and inhibitory links between event re

67 was achieved, but this agreement was rarely forged explicitly.

68 cision in moderately degraded DNA and can be forged for high throughput analysis.

69 Geometrically constrained radical cations, forged from the one-electron oxidation of transiently ge

70 mproved understanding of NK cell biology has forged greater awareness that these cells play integral

71 Our work forges ground in showing that the mutability of RNA viru

72 icacy of anti-inflammatory treatments, while forging guidelines for future intelligent clinical trial

73 tron stars are a long-sought production site forging heavy elements by r-process nucleosynthesis.

74 The development version is hosted by R-Forge: http://r-forge.r-project.org/projects/adephylo/.

75 s the specific linkages of the micromere GRN forged in the evolutionary process by which the skeletog

76 sed on the model of genetics and inheritance forged in the modern synthesis that they will require re

77 sting helices in proteins; coiled coils were forged in unison with the fold of the whole protein.

78 lementary, researchers and policy makers can forge interdisciplinary, international, and intergenerat

79 a common type of endogenous DNA damage, can forge interstrand DNA-DNA cross-links via reaction with

80 Antibody fragments have been forged into multivalent and multi-specific reagents, lin

81 ric histone Cse4 from its host yeast cell to forge its own centromere and finally revealing how the 2

82 owered by a unique C-H arylation reaction to forge its polycyclic core.

83 our its own maintenance, a case of evolution forging its own path.

84 us attention on three specific contexts: (i) forging linkages between the engineering and health comm

85 This observation begins the process of forging links between genetic analysis of RNAi from dive

86 uncertainty is largely due to the hurdle of forging links between theory and brain [7-9].

87 ary tract and worked closely with urologists forged major advances in urinary tract imaging and inter

88 eukaryotes and showcases the role of LGT in forging metabolic mosaics of ancestral and newly acquire

89 compared directly to commercially die-upset forged (MQIII-F) material made from the same MQU-F powde

90 orts to reconstruct the ancient mergers that forged multiple lines of photosynthetic microbial eukary

91 clinicians and behavioral health specialists forge new collaborative relationships that enhance the d

92 ent an ideal starting material with which to forge new connections.

93 These findings forge new links between cell-fate specification and morp

94 out the evolutionary time scales required to forge new ones.

95 unities and challenges to physicians as they forge new relationships with NPCs and as their own spect

96 Resources for Biodefense Research program is forging new collaborations between immunologists and inf

97 Forging new memories for facts and events, holding criti

98 Our laboratory at Rice University has forged numerous collaborations with clinicians and basic

99 Rapid sinter-forging of a green compact to near theoretical density w

100 Two models have been forged on the basis of clinical observations: a first mo

101 ites and combined with additional domains to forge one of the largest bacteriophage genes to date (14

102 means of sending a message, which cannot be forged or repudiated, with security verified by informat

103 This partnership, forged over many millennia of coevolution, is based on a

104 Nevertheless, nature forged populations adapted to these challenges.

105 The process, which provides a direct way to forge quaternary stereocenters with high fidelity, relie

106 ponse data as the package ivDrug at http://r-forge.r-project.org.

107 lrgpr is an R package available from lrgpr.r-forge.r-project.org.

108 d on the adegenet website: http://adegenet.r-forge.r-project.org/.

109 /html/pathview.html and at http://Pathview.r-forge.r-project.org/.

110 pment version is hosted by R-Forge: http://r-forge.r-project.org/projects/adephylo/.

111 anderson.org/main/OOMPA:Overview or http://r-forge.r-project.org/projects/supercurve/.

112 ces of remote control of selectivity through forging reversible covalent interactions.

113 nd a reductive hydroxyketone ring closure to forge ring V.

114 r and nonsmallholder agriculture are keys in forging rural-urban links, where both farm and nonfarm a

115 llaboration networks, where people prefer to forge social ties with people who have professions diffe

116 how its constituents communicate with us to forge stable and mutually advantageous relationships.

117 New C(sp(3))-C(sp(2)) bonds are forged starting from abundant and inexpensive natural am

118 st an intentional and systematic approach to forging strong, sustained partnerships between public se

119 icroorganisms has emerged as a key factor in forging such communities.

120 halide and a p-methoxy semiquinone aminal to forge the anthraquinone moiety of the molecule.

121 and subsequent nucleophilic ring opening to forge the C-N bond.

122 3))-H alkenylation reaction to strategically forge the C1-C2 bond, and (3) a ring-closing metathesis

123 uthenium-catalyzed alkene-alkyne coupling to forge the C15-C16 bond.

124 Two parallel strategies were exploited to forge the carbazole core: 6pi-electrocyclization/aromati

125 nd an intermolecular Diels-Alder reaction to forge the carbocyclic core in a concise and stereoselect

126 tones by a Stille cross-coupling approach to forge the central diene moiety and demonstrate this stra

127 mediated strategy for the key cyclization to forge the central region of the molecule, ring C.

128 rm the dimer interface, the strategy used to forge the channel for electrostatic recognition of super

129 rically diverse aryl iodides and bromides to forge the corresponding C-N bonds, which are of high int

130 and (ii) a 6-exo-dig radical cyclization to forge the final piperidinyl ring system.

131 specialization that supports infants as they forge the foundational links between human language and

132 e aimed to compare the selective forces that forge the IgG4 and IgE repertoires in allergic asthma.

133 f cells into the "bulldozer" aggregates that forge the interconnecting furrows.

134 This strategy allowed us to efficiently forge the intricate 5-8-5 fused ring systems found in nu

135 the pyran unit, and a Suzuki homocoupling to forge the key biaryl bond.

136 he various implicit learning operations that forge the learning curve.

137 cular Horner-Wadsworth-Emmons olefination to forge the macrocyclic ring.

138 core, a key Fischer indolization reaction to forge the natural product's carbon framework, and a seri

139 yama-Kishi cyclization of iodoaldehyde 56 to forge the oxacyclononane ring and the C6 hydroxyl stereo

140 ed cascade rearrangement of epoxyketone 6 to forge the polyoxygenated 2,7-dioxabicyclo[2.2.1]heptane

141 ducts so obtained were further elaborated to forge the second macrocycle of the molecule.

142 scade ene-yne-ene ring closing metathesis to forge the tetracyclic morphine core.

143 and confirms the need for continuing work to forge the way for new drug discovery.

144 e-dependent non-heme Fe(II) dioxygenase that forged the azetidine ring on the okaramine skeleton.

145 a samarium-induced cyclization process that forged the final ring of the carbon framework.

146 a, putamen, and thalamus, which collectively forged the formation of the functional speech connectome

147 zed isomerization/rearrangement process that forges the central core of the molecule and (2) two faci

148 o reviews the origins and strategies used in forging the WHO FCTC, from the perspective of one who wa

149 Ac) shell, the key cellular adaptations that forge this link are unclear.

150 with 4-hydroxy-1,6-enynes by a process that forges three C-C bonds, one C-H bond, and two new stereo

151 e final two bonds of the core structure were forged through a samarium diiodide-mediated ketyl radica

152 ing of these petrogenetic processes has been forged through the accessory mineral zircon, which has c

153 bis-spirocyclic tetrahydrothiophene ring was forged through the Stevens rearrangement of a sulfonium

154 ic specialization and cross feeding, thereby forging trophic relationships between members of the gut

155 In a single step, these reactions (1) forge two new C-C bonds under mild conditions, (2) produ

156 The cascade process forges two bonds en route to spirocyclized oxindole and

157 The R package for MPCBS is registered on R-Forge under project name MPCBS.

158 The challenging 11-membered ring was forged via a diastereoselective thionium ion initiated c

159 e family, containing a bridgehead alkene, is forged via a vicinal difunctionalization/Diels-Alder str