ライフサイエンスコーパス: forkhead

1 ture a conserved DNA-binding domain known as forkhead.

2 recently identified Saccharomyces cerevisiae Forkhead 1 (Fkh1) and Forkhead 2 (Fkh2) as required for

3 ccharomyces cerevisiae Forkhead 1 (Fkh1) and Forkhead 2 (Fkh2) as required for the clustering of a su

4 on in the phosphopeptide-binding site of the forkhead-associated (FHA) domain disrupted normal Mnk lo

5 r (APLF) is a DNA repair factor containing a forkhead-associated (FHA) domain that supports binding t

6 Forkhead-associated (FHA) domains are phosphopeptide rec

7 Mutations of the ligand-binding residues of Forkhead-associated (FHA) domains of Rad53, Dun1, Xrs2,

8 It harbors both a plant homeodomain and a forkhead-associated domain implicated in epigenetic reco

9 on-dependent interaction site in XRCC1 and a forkhead-associated domain in PNKP.

10 A hypomorphic mutation in the forkhead-associated domain of Unc-104, unc-104(bris), im

11 ecruits BAP1 to the target genes through the forkhead-associated domain, which interacts with Thr(P)-

12 n the Dun1 activation loop, but not the Dun1 forkhead-associated domain.

13 In contrast, Myb- and forkhead-binding sites are underrepresented in both earl

14 ells were found to coexpress pioneer factors forkhead box (Fox) a1 and Foxa2 before neuroendocrine di

15 rect mechanisms, with the latter mediated by Forkhead box (FOX) family transcription factors.

16 ne expression profiling revealed a subset of Forkhead box (Fox) genes that are regulated by Shh signa

17 These conditions activate the family of Forkhead Box (Fox) O transcription factors.

18 racetylation and nuclear localization of the forkhead box (Fox) protein FoxO3a, followed by enhanced

19 Forkhead Box (Fox) proteins share the Forkhead domain, a

20 The Saccharomyces cerevisiae Forkhead Box (FOX) proteins, Fkh1 and Fkh2, regulate div

21 n transcription in a manner dependent on the forkhead box (FOX) transcription factor FOXG1.

22 Forkhead box (Fox) transcription factors are evolutionar

23 Here we discovered two Forkhead box (FOX) transcription factors, FOXK1 and FOXK

24 Forkhead box (FOX)P3 is a requisite transcription factor

25 tion of glucocorticoid receptor signaling or forkhead box (FOXO) 1/3 inhibition abolished the rapamyc

26 We previously found loss of forkhead box A1 (FOXA1) expression to be associated with

27 Forkhead box A1 (FOXA1) is an FKHD family protein that p

28 Two TFs, i.e. FoxA1 (Forkhead box A1) and AP-2gamma (activating enhancer bind

29 g enhancers, which are also dependent on the forkhead box A1/A2 (FOXA1/A2) transcription factors (TFs

30 Forkhead box a2 (FOXA2) is a transcription factor expres

31 with NK2 homeobox 1 (Nkx2.1) for binding to forkhead box A2 (Foxa2) to drive hepatic differentiation

32 homeobox 1 (PDX1), NK6 homeobox 1 (NKX6.1), forkhead box A2 (FOXA2), and NK2 homeobox 2 (NKX2.2) - f

33 transcription factors Nkx2.1, Gata6, Foxa2 (forkhead box a2), and Foxf1 mimic the expression pattern

34 n in the developmental transcription factor, forkhead box A2, FOXA2 (c.505T>C, p.S169P) in a child wi

35 ing in vivo microarray analysis, we identify forkhead box C1 (Foxc1) as a transcriptional partner of

36 tionally ablating a key transcription factor Forkhead box C1 (FOXC1) expressed in hair follicle SCs (

37 The Forkhead box C1 (FOXC1) transcription factor has been sh

38 The Forkhead box C1 (FOXC1) transcription factor is involved

39 t the expression of two genes in the region, forkhead box E1 (FOXE1) and PTC susceptibility candidate

40 The locus also comprises the forkhead box E1 (FOXE1) gene, which is implicated in thy

41 Alterations in the forkhead box F2 gene expression have been reported in nu

42 FOXF1, a member of the forkhead box family of transcription factors, has been p

43 Lindau tumor suppressor (VHL) protein in the forkhead box FOXD1 cell lineage, from which stromal prog

44 Forkhead box g1 (Foxg1) is a nuclear-cytosolic transcrip

45 Based on these findings, we discover that forkhead box H1 (FOXH1), a transcription factor required

46 se-pair duplication in the first exon of the forkhead box I3 gene (FOXI3) shared by all three breeds.

47 The mechanistic role of cross talk between Forkhead box M1 (FOXM1) and HGF/Met signaling in promoti

48 st cancer cell lines, we found that oncogene forkhead box M1 (FOXM1) interacts with SMAD3 to sustain

49 Forkhead box M1 (FOXM1) is a transcription factor recent

50 ndent expression of the transcription factor forkhead box M1 (FOXM1) is necessary for cell proliferat

51 elated gene-1 (Brg1) chromatin remodeler and forkhead box M1 (FoxM1) transcription factor cooperate w

52 endothelial reparative transcription factor Forkhead box M1 (FoxM1).

53 ncubation with thiostrepton (an inhibitor of forkhead box M1 [FOXM1]) or verteporfin (inhibitor of th

54 s, including the GRB2 interactome as well as Forkhead Box M1 and its downstream target, the tryptopha

55 by modulating transcription factors p53 and forkhead box M1, which was not observed with sequential

56 s involved in mitotic progression, including Forkhead Box M1.

57 By using this resource, we identified a forkhead box MI (FOXM1) regulatory network as a major pr

58 ial cell (TEC)-specific transcription factor Forkhead box N1 (FOXN1) has been implicated as a compone

59 The forkhead box N1 (Foxn1) protein is the key regulator of

60 ional regulator of epithelial cell function, Forkhead Box N1 (Foxn1), and its two regulated targets,

61 vation of the downstream signaling molecules forkhead box O (FOXO) and p70 S6 kinase in a tissue and

62 tors and co-factors including members of the Forkhead box O (FoxO) family and beta-catenin.

63 Evasion of forkhead box O (FOXO) family of longevity-related transc

64 The forkhead box O (FOXO) family of transcription factors is

65 activity of the DAF-16 transcription factor (forkhead box O (FOXO) homologue), whose global targets w

66 -dependent protein kinase (PKG2) to activate forkhead box O (FoxO) in colon cancer cells and in the c

67 Here we report that the forkhead box O (FOXO) transcription factor FOXO1 is an e

68 Here, we show that forkhead box O (FoxO) transcription factor, a central re

69 Forkhead box O (FoxO) transcription factors are key regu

70 which results in the activation of mammalian forkhead box O (FOXO) transcription factors.

71 photoreceptor differentiation by modulating Forkhead box O (FOXO), target of rapamycin, and Hippo si

72 ectin-5'-AMP-activated protein kinase (AMPK)-forkhead box O (FOXO)-signaling axis stemming from at th

73 nder the control of the transcription factor Forkhead box O (Foxo).

74 Alternatively, decreased forkhead box O 1 (FOXO1) and increased K48 polyubiquitin

75 The regulation of catabolic signalling via forkhead box O 1 and protein ubiquitination is SIRT1 dep

76 eptor PPARalpha and nuclear translocation of forkhead box O 1, which cause cardiomyopathy.

77 rt that tribbles homologue 2 (TRIB2) ablates forkhead box O activation and disrupts the p53/MDM2 regu

78 ed new PERK substrates transcription factors Forkhead box O protein and diacyglycerol a lipid signali

79 ts of JH on growth rate are dependent on the forkhead box O transcription factor (FOXO), which is neg

80 nscription factor activity by overexpressing forkhead box O transcription factor 1 rescued the abnorm

81 ycin activity by rapamycin or restoration of forkhead box O transcription factor activity by overexpr

82 lian target of rapamycin and inactivation of forkhead box O transcription factor-signaling pathways.

83 ements of insulin signaling pathways such as forkhead box O transcriptional signaling or glucose tran

84 antagonist, which led to p-Tie2 suppression, forkhead box O1 (FOXO1) activation, increased ANG2 expre

85 Concomitant deletion of Forkhead Box O1 (Foxo1) in these livers rescued the decr

86 Because forkhead box O1 (FOXO1) is a major effector of this path

87 Transcription factor forkhead box O1 (FoxO1) regulates energy expenditure (EE

88 As a result, forkhead box O1 (FoxO1), a transcription factor that is

89 xins and was reinforced by the expression of forkhead box O1 (FOXO1).

90 tivated the phosphoinositol 3-kinase/Akt and forkhead box O1 pathways (showing a dose-dependent effec

91 clin-encoding gene (Ostn) transcription from forkhead box O1 transcription factor inhibition.

92 PAX3-FOXO1 (paired box gene 3 fused with forkhead box O1) fusion RNA, which is considered a hallm

93 f the stress-responsive transcription factor forkhead box O3 (FoxO3) in mediating injury-induced prox

94 y, overexpression of a transcription factor, forkhead box O3 (FoxO3), which is implicated in aging, b

95 l target of rapamycin complex 1 (mTORC1) and forkhead box o3 (Foxo3a) acted downstream of Akt to infl

96 Mechanistically, transcription factor forkhead box O3 (Foxo3a) physically interacts with Tet2

97 tion 2 homolog 1 (SIRT1), which deacetylates forkhead box o3 (FOXO3a), leading to repression of proap

98 Moreover, Forkhead box O3 transcription factor (FoxO3) is further

99 Transcription factor forkhead box O4 (FoxO4) regulates a variety of biologica

100 vated Akt1 increased both GSK3alpha/beta and forkhead box of the O class transcription class 3 (FoxO3

101 Forkhead Box P (FOXP) transcriptional repressors play a

102 shown that loss of the transcription factors forkhead box P1 (Foxp1) and Foxp4, which are critical fo

103 iR-150 expressed relatively higher levels of forkhead box P1 (FOXP1) and GRB2-associated binding prot

104 Mutations in the transcription factor Forkhead box p1 (FOXP1) are causative for neurodevelopme

105 enetic approaches to investigate the role of forkhead box P1 (FOXP1) in transcriptional control of MS

106 High expression of the forkhead box P1 (FOXP1) transcription factor distinguish

107 errant AKT activity and decreased downstream forkhead box P1 (FOXP1)/FGF and NOTCH1/EPHB2 signaling,

108 n the gene encoding the transcription factor forkhead box P2 (FOXP2) result in brain developmental ab

109 Mutations in the human forkhead box P2 gene, FOXP2, cause developmental verbal

110 associated with decreased expression of the forkhead box P3 (FoxP3) 44- and 47-kDa splicing forms, o

111 crophages had an enhanced capacity to induce forkhead box P3 (FOXP3) expression in naive CD4(+) T cel

112 The transcription factor forkhead box P3 (Foxp3) is essential for specifying the

113 ve insights into to the demethylation of the forkhead box P3 (Foxp3) locus during the induced T regul

114 on of the Treg cell key transcription factor forkhead box p3 (Foxp3) was observed.

115 okine production by splenocytes, and splenic forkhead box P3 (FOXP3)(+) regulatory T (Treg) cells wer

116 and IL-10-producing regulatory CD4(+)CD25(+) forkhead box p3 (Foxp3)(+) T cells.

117 immunologic conditions, lymphocyte subsets, forkhead box P3 (FOXP3)(+) Treg cell levels, and phenoty

118 We analyzed CD4(+) forkhead box P3 (Foxp3)(+) Treg cells that were isolated

119 Although forkhead box P3 (FOXP3)(+)CD4(+) regulatory T (Treg) cel

120 ocyte activation gene 3 (LAG3)(+), CD49b(-), forkhead box P3 (Foxp3)(-) regulatory T cells in vitro,

121 X) syndrome, which is caused by mutations in forkhead box P3 (FOXP3), and IPEX-like disorders caused

122 cells that express the transcription factor forkhead box P3 (Foxp3).

123 3, interleukin-6, tumor necrosis factor, and forkhead box P3 prominently placed in a regulatory conne

124 In addition, pancreatic forkhead box P3 regulatory T cells were increased in GF-

125 xperiments, ex vivo hapten presentation, and forkhead box p3 regulatory T-cell conversion.

126 etal DCs effectively primed antigen-specific forkhead box P3(+) regulatory T cells after in vitro coi

127 Forkhead box P3(+) T regulatory cells (Tregs) are key pl

128 ory circuit encompassing tolerogenic DCs and forkhead box P3(+) Treg cells that could be targeted for

129 s through generation of strongly suppressive forkhead box P3(+) Treg cells.

130 antigen-specific regulatory T cells (CD25(+) forkhead box P3(+)) at the expense of effector (IFN-gamm

131 n accumulation of activated CD4(+) Foxp3(-) (forkhead box P3) IFN-gamma(+) T cells in the heart-drain

132 ng, which has the capacity to stimulate CD4+ forkhead box P3+ (Foxp3+) regulatory T cells (Tregs), ac

133 hat its deficiency causes a cell-autonomous, Forkhead box P3-independent failure of peripheral CD4(+)

134 Elevated CD4(+) forkhead box P3-positive (Foxp3+) T cells were evident i

135 caused a reduction in IL-13(+) CD4 T cells, forkhead box P3-positive regulatory T cells, and IL-5(+)

136 tinaldehyde dehydrogenase and specialized in forkhead box p3-positive regulatory T-cell conversion.

137 e and were regulated specifically by p53 and forkhead box P3.

138 Adoptive transfer of forkhead box protein (FOX)3 regulatory T (Treg) cells of

139 ptor (ER), glucocorticoid receptor (GR), and forkhead box protein 1 (FoxA1) are significant factors i

140 totic neutrophil-derived proteins, including forkhead box protein 1 (FOXO1), to T cells.

141 ressor that is transcriptionally silenced by forkhead box protein 1 (FOXP1) in the aggressive, activa

142 ession of the oncogenic transcription factor forkhead box protein 1 (FOXP1) is a common feature of di

143 s of the signature Treg transcription factor Forkhead box protein 3 (Foxp3) and Treg function under v

144 The identification of CD25 and subsequently Forkhead box protein 3 (Foxp3) as markers for regulatory

145 on between the expression of the Treg marker forkhead box protein 3 (FoxP3) in biopsies of PTLDs and

146 eg function and increased methylation in the forkhead box protein 3 (FOXP3) locus (P < 0.05), conditi

147 CD4(+) Forkhead box protein 3 (Foxp3)(+) regulatory T cells (Tr

148 ave a dysfunction or lack of gluten-specific forkhead box protein 3 (FOXP3)(+) Treg cells.

149 challenge, symptoms, Treg cell numbers, and forkhead box protein 3 (Foxp3), TH2 and TH17 cytokine, a

150 nterparts (pTregs) are imprinted with unique Forkhead box protein 3 (Foxp3)-dependent and independent

151 Forkhead box protein 3 (FoxP3)-expressing natural Treg c

152 y associated with an increased expression of forkhead box protein 3 and a decreased expression of Cep

153 ing on a farm and increased peripheral blood forkhead box protein 3 expression and correlated inverse

154 protein 3-positive Treg cells compared with forkhead box protein 3-negative conventional T cells.

155 , promote the expansion of immunosuppressive forkhead box protein 3-positive CD8+ regulatory T cells,

156 elevance, HuMoSCs induce long-lasting memory forkhead box protein 3-positive CD8+ regulatory T lympho

157 that IVIg significantly increases numbers of forkhead box protein 3-positive regulatory T (Treg) cell

158 tolerance restoration, favoring expansion of forkhead box protein 3-positive regulatory T cells along

159 n IL-10 production, numbers of CD4(+)CD25(+) forkhead box protein 3-positive regulatory T cells, and

160 teins and the cytokine production profile of forkhead box protein 3-positive Treg cells compared with

161 lbumin, suppressing the normal generation of forkhead box protein 3-positive Treg cells while promoti

162 configures committed Tregs stably expressing forkhead box protein 3.

163 Forkhead box protein A1 (FOXA1) is a pioneer factor of e

164 T/enhancer-binding protein beta (C/EBPbeta), forkhead box protein A2 (FOXA2), and retinoid X receptor

165 We have recently shown that the forkhead box protein A3 (Foxa3) is a calorie-hoarding fa

166 ly demonstrated that the winged helix factor forkhead box protein A3 (Foxa3) regulates the expansion

167 or 5 (ATF5), early growth response 1 (EGR1), forkhead box protein A3 (FOXA3), JUNB, Kruppel-like fact

168 MAPK signaling, and the transcription factor Forkhead Box Protein C2 (FOXC2) known to promote cancer

169 , including increases in multicilin gene and forkhead box protein J1 expression and inhibition of the

170 ace, (ii) expression of transcription factor forkhead box protein J1, and (iii) presence of multiple

171 e inhibitor BI2536 suppressed binding of the Forkhead box protein K1 (FOXK1) transcriptional represso

172 the converse experiment and lineage-labeled forkhead box protein L1(Foxl1)-positive hepatic progenit

173 eatured upstream binding sites recognized by forkhead box protein M1 (FoxM1), a key transcription fac

174 rc-focal adhesion kinase (FAK) signaling and Forkhead box protein M1 (FoxM1).

175 f the promitotic transcription factor FOXM1 (Forkhead box protein M1).

176 Transcription factor Forkhead box protein M1b (FoxM1b) plays an important rol

177 transcription factors such as T-cell factor, forkhead box protein O, and hypoxia inducible factor 1al

178 effector genes and the transcription factors forkhead box protein O1 (Foxo1) and Klf2 in DP thymocyte

179 Signaling to regulate forkhead box protein O1 (FOXO1) may be the most importan

180 PGE2, through PI3K/AKT activation, promoted Forkhead box protein O1 (FOXO1) phosphorylation and FOXO

181 Moreover, forced expression of forkhead box protein O1 (FoxO1), an antagonist for activ

182 3-kinase (PI3K) signaling involving PTEN and forkhead box protein O1 (Foxo1), supporting autoantibody

183 ductive effects of the transcription factor, forkhead box protein O1 (FoxO1).

184 ia deacetylation of the transcription factor Forkhead box protein O1 (FoxO1).

185 ition or expression of constitutively active forkhead box protein O1 (FoxO1).

186 racterized by expression of the paired box 3-forkhead box protein O1 (PAX3-FOXO1) fusion oncogene.

187 y preventing nuclear translocation of FoxO1 (Forkhead box protein O1) and beta-catenin, which contrib

188 am through protein kinase B (AKT) and FOXO1 (forkhead box protein O1) to drive synergistic expression

189 n sequencing screens led to the discovery of forkhead box protein O4 and signal transducer and activa

190 The prognostic value of forkhead box protein P1 (FOXP1) protein expression in tu

191 the upregulation of the transcription factor Forkhead box protein P1 (Foxp1), which prevents CD8(+) T

192 sion in cardiomyocytes and overexpression of Forkhead box protein P1 attenuated miR-206-induced cardi

193 miR-206 negatively regulates Forkhead box protein P1 expression in cardiomyocytes and

194 iating hypertrophy and survival by silencing Forkhead box protein P1 in cardiomyocytes.

195 ac hypertrophy and survival, suggesting that Forkhead box protein P1 is a functional target of miR-20

196 A mutation of the forkhead box protein P2 (FOXP2) gene is associated with

197 The gene coding for the forkhead box protein P2 (FOXP2) is associated with human

198 ositive for the nuclear transcription factor Forkhead box protein P2 (FoxP2).

199 enotype in Vdelta2 T cells, characterized by forkhead box protein P3 (FoxP3) expression and suppressi

200 rphan nuclear receptor gamma (RORgammat) and Forkhead box protein P3 (Foxp3).

201 not Akt2-deficient, ECs, including eNOS and Forkhead box proteins.

202 eport that nuclear AURKA can be recruited by Forkhead box subclass M1 (FOXM1) as a co-factor to trans

203 y decreasing ROS through increased levels of forkhead box transcription factor 3a (FOXO3a) and a down

204 Inactivating mutations in the Forkhead Box transcription factor F1 (FOXF1) gene locus

205 The forkhead box transcription factor FOXC1 plays a critical

206 The forkhead box transcription factor FOXM1 is an essential

207 found that heightened expression of FoxM1, a Forkhead box transcription factor, is regulated during d

208 e present study was to determine the role of forkhead box transcription factors in modulating lipid m

209 (HCV) infection modulates the expression of forkhead box transcription factors, including FoxO1 and

210 nce class switching in a manner dependent on forkhead box, subgroup O (FoxO) transcription factors.

211 thway and promoting activation of Drosophila forkhead box, subgroup O transcription factor.

212 Here, we report that Foxq1, a forkhead box-containing transcription factor and EMT-ind

213 By lineage-specific deletion of the forkhead box-O 1 (FOXO1) transcription factor, we demons

214 pression of Foxp1/2/4 proteins, comprised of Forkhead-box (Fox) transcription factors of the Foxp sub

215 Forkhead-box domain (Fox) containing family members are

216 Here, we show that the forkhead-box transcription factor Foxi3 inhibits formati

217 This enhancer is dependent on Forkhead-Box transcription factors and functionally inte

218 el), and the disease suppression depended on forkhead-box-protein-P3(foxp3)(+) Treg cells.

219 Currently, the role that forkhead boxO activation plays in the development of mec

220 hragm through the use of a dominant-negative forkhead boxO adeno-associated virus vector delivered di

221 In this regard, the forkhead boxO family of transcription factors is activat

222 s determined by inhibiting the activation of forkhead boxO in the rat diaphragm through the use of a

223 Forkhead boxO is necessary for the activation of key pro

224 lated animals treated with dominant-negative forkhead boxO showed a significant attenuation of both d

225 In addition, inhibiting forkhead boxO transcription attenuated the mechanical ve

226 tively, these results suggest that targeting forkhead boxO transcription could be a key therapeutic t

227 diaphragm during mechanical ventilation, and forkhead boxO-specific transcription can lead to enhance

228 the stop codon location) or the DNA-binding forkhead domain (Fisher exact test, P = 0.021).

229 etermined the crystal structure of the FOXP3 forkhead domain bound to DNA.

230 The forkhead domain of FOXC1 is essential for the competitio

231 librium folding and binding mechanism of the forkhead domain of wild-type FoxP1, and of two mutants t

232 ity, and the Myb TF acts in concert with two forkhead domain TFs and Polo kinase to regulate cardiac

233 Forkhead Box (Fox) proteins share the Forkhead domain, a winged-helix DNA binding module, whic

234 Forkhead factors do not regulate TAD formation, but do p

235 dent increase in the nuclear localization of forkhead family of transcription factor 3 (FoxO3).

236 The forkhead family of transcription factors (Fox) controls

237 Foxp1 is a member of the Forkhead family of transcription factors expressed selec

238 FOXM1 is a transcription factor of the Forkhead family that is required for cell proliferation

239 FOXA1 is a transcription factor of the forkhead family that is required for prostate epithelial

240 We have characterized a mouse mutant for the Forkhead family transcription factor Foxi3, which is exp

241 ent signaling results in upregulation of the forkhead family transcription factor, FoxM1, and its tra

242 multifunctional transcription factor of the forkhead family.

243 The Forkhead (FKH) transcription factor FOXM1 is a key regul

244 In this study, we identified three forkhead (Fkh)-binding sites in the 140-bp region of the

245 ave examined the binding properties of three Forkhead (FOX) transcription factors, FOXK2, FOXO3 and F

246 The members of the class O forkhead (FOXO) transcription factor family, including F

247 rm (CM) as eliminating the functions of both Forkhead genes in the same Drosophila embryo results in

248 cification phenotype in embryos lacking both Forkhead genes.

249 Forkhead O transcription factors (FOXOs) have been impli

250 the transcriptional level directly through a Forkhead response element (FHRE) in its promoter.

251 NBS1 at the transcriptional level through an forkhead response element on its promoter.

252 y transactivate the FOXM1 promoter through a Forkhead response element, whereas FOXM1 can activate AU

253 nd antagonizing Foxo1 binding to a consensus forkhead site in this cis-regulatory element that we sho

254 Interestingly, solved forkhead structures of members from the P subfamily (Fox

255 Here, we show that the Forkhead TFs Checkpoint suppressor homologue (CHES-1-lik

256 and illustrate the pleiotropic functions of Forkhead TFs in different aspects of cardiogenesis.

257 This process is mediated by the Forkhead TFs regulating the fibroblast growth factor rec

258 terns determining growth outcomes, including Forkhead TFs, FOSL1, and PLAG1.

259 Second, we deduced the forkhead transcription factor (FOXO) family to be a down

260 to do so by converging on the regulation of forkhead transcription factor (FOXO).

261 Forkhead transcription factor box A2 (FOXA2) is uniquely

262 The expression of the forkhead transcription factor checkpoint suppressor 1 (C

263 A), independent of p53, but dependent on the forkhead transcription factor class-O family member, FOX

264 diated by intrinsic neuronal activity of the forkhead transcription factor DAF-16/FOXO.

265 The activity of the forkhead transcription factor FKH-9 in neurons is requir

266 regeneration phenotypes and that RNAi of the forkhead transcription factor FoxA, which is expressed i

267 sis and defined a CSVD locus adjacent to the forkhead transcription factor FOXC1.

268 nic stem to epiblast cells and uncovered the forkhead transcription factor FOXD3 as a major regulator

269 Here, we describe mutations in the forkhead transcription factor FOXE3 that predispose muta

270 mesodermal precursors expressing or not the Forkhead transcription factor FOXF1.

271 Here, the authors identify the forkhead transcription factor Foxh1 as regulating FLK1+

272 We identify the forkhead transcription factor Foxh1, in part through Eom

273 membrane transport proteins regulated by the forkhead transcription factor FOXI1.

274 While mutations of the forkhead transcription factor FOXL2 are associated with

275 The forkhead transcription factor FOXM1 has a key role in DN

276 nstrate that the expression of the oncogenic forkhead transcription factor FOXM1 is upregulated by GO

277 rongly correlated with the expression of the forkhead transcription factor FoxM1, which binds to the

278 the key nodes in the metabolic network, the forkhead transcription factor FOXO has been shown to int

279 evelopment by regulating the activity of the forkhead transcription factor Foxo.

280 ce, but Akt-dependent phosphorylation of the forkhead transcription factor FoxO1 at serine 256, which

281 D31 signals prevents the localization of the forkhead transcription factor FoxO3 to the nucleus, thus

282 The forkhead transcription factor FoxO6 is prominently expre

283 Expression of the forkhead transcription factor FOXP1 is essential for ear

284 The forkhead transcription factor FOXP1 is involved in B-cel

285 Heterozygous disruptions of the Forkhead transcription factor FoxP2 impair acquisition o

286 mitotic genes in close proximity to Fkh2, a forkhead transcription factor previously implicated in r

287 on and represses the expression of FOXP2, a forkhead transcription factor tightly associated with sp

288 In this context, the Forkhead transcription factor, Foxo3, amplified GATA-1-m

289 Sep1, another forkhead transcription factor, is an activator for a sma

290 osphorylation of FOXO3a, a tumor suppressive forkhead transcription factor, leading to its cytoplasmi

291 FOX:ETS motif, a composite binding site for Forkhead transcription factors and the Ets transcription

292 Forkhead transcription factors are essential for diverse

293 From yeasts to humans, forkhead transcription factors are involved in mitotic g

294 fibroblast growth factor signaling and four Forkhead transcription factors consist the central part

295 Foxc1 belongs to the forkhead transcription factors family, which plays a cri

296 t early origins through its interaction with forkhead transcription factors Fkh1 and Fkh2.

297 d Hi-C experiments on cells depleted for the Forkhead transcription factors, Fkh1 and Fkh2, previousl

298 Forkhead transcriptional factor O1 (FoxO1) in the hypoth

299 aracterised genome-wide binding sites of the forkhead/winged helix transcription factor Foxa1, which

300 tions, SRL, however, significantly increased forkhead/winged helix transcription factor P3 (FOXP3) Tr