ライフサイエンスコーパス: form

1 s for which growth has a specific functional form.

2 f shape on some exogenous cause or effect of form.

3 hed fraction but also was present in soluble form.

4 estigation of water in its metastable liquid form.

5 and results in a CYP126A1 monomeric crystal form.

6 d, consequently, the mechanism by which they form.

7 Golgi and only if in a complex-glycosylated form.

8 balance between the conjugated/de-conjugated forms.

9 ntributing to the diversity of double flower forms.

10 NOB demonstrated that only sulfinamides were formed.

11 ct types of actin-based membrane protrusions formed.

12 elatively little is known about how they are formed.

13 e (2) substituting its para-fluorine atom to form 2-(4-cyanotetrafluorophenyl)-4,4,5,5-tetramethyl-4,

14 from weaker X-H bonds such as TEMPO-H to re-form 2.

15 nd secondary benzyl alcohols with indoles to form 3-benzylated indoles and H2O that is catalyzed, for

16 The initially formed 5-alkenyl iminohydantoins may be hydrolyzed and o

17 In the retina, endothelial cells form a blood-retina barrier by virtue of tight junctions

18 shaped structure, where the two Cas2 domains form a central hub (twofold axis of symmetry) flanked by

19 find that EmMBD2/3 and EmGATAD2A/B proteins form a coiled-coil interaction known to be critical for

20 uminum-activated malate transporters (ALMTs) form a family of anion channels in plants, but little is

21 further dimerize through SAV1 WW domains to form a heterotetramer, in which MST2 undergoes trans-aut

22 tend to residue 137 and that residues 90-125 form a novel loop that links Sac3 to Thp1.

23 P) the human RAD51 (HsRAD51) recombinase can form a nucleoprotein filament (NPF) on double-stranded D

24 RNA polymerase and ribosomes form a one-to-one complex with a micromolar dissociation

25 We demonstrated that DNMT1 and KIT form a positive regulatory loop, in which ectopic DNMT1

26 These surfaces allow ASF1A to form a quaternary complex with both sNASP and H3-H4.

27 Four isolates from domestic bathrooms which form a sister species with Exophiala lecanii-corni are d

28 ether as two heptad-repeat regions refold to form a six-helix bundle structure that can be specifical

29 scape behavior shows that mice spontaneously form a spatially precise memory of the location of shelt

30 abin molecule in a neurabin homo-oligomer to form a ternary complex, representing a novel mode of reg

31 1R2 leads to major conformational changes to form a TM6/TM6 interface between TMDs of TAS1R2 and TAS1

32 F) insert into the target cell membrane, and form a transient intermediate that pulls the viral and c

33 By using the C35S mutant of TRX, which formed a metastable mixed disulfide bond with TG2, we de

34 as a trigger to initiate the nonlinear HCR, forming a chain-branching growth of DNA dendrimer by sel

35 es at the corners of the Brillouin zone (BZ) forming a Dirac cone.

36 show how brain regions tend to coordinate by forming a highly hierarchical chain-like structure of ho

37 ection angle with different number of coils, forming a plasma structure similar to that observed in t

38 se import and assembly protein 40 (AtMIA40), forming a protein complex.

39 is stable to heat and chemical denaturants, forming a robust layer that would contribute to overall

40 substituted with a beta-ketoester (BC half) forms a propenone bearing the two halves (a hydrobilin a

41 Our results suggest that Hrd1 forms a retro-translocation channel for the movement of

42 dily adapted to other imaging modalities and forms a starting point for further steps of data analyti

43 between a peripheral element of the RNA that forms a T-loop module and a subset of nucleotides in the

44 nd wild-type and mutated WDR1 Mutant protein formed aggregates that appeared to accumulate pyrin; thi

45 oltage-gated CaV2.1 channels comprise a pore-forming alpha1A subunit with auxiliary alpha2delta and b

46 LC from all patients formed amyloid-like aggregates, albeit with individually

47 nd moderately destabilized sw ApoMb variants form amyloids, whereas their strongly destabilized mutan

48 we show that lamin A/C expressing cells can form an actin cap to resist nuclear deformation in respo

49 These neurons form an anterior neurosecretory center expressing many n

50 hRNA targeting IGF-1 receptor were unable to form an axon and, therefore, neuron polarity was absent.

51 ey propagate along the auditory pathway, and form an empirical framework to study the representationa

52 ath for lipids in scramblases has changed to form an enclosed aqueous pore that is largely shielded f

53 or causes of vision impairment and blindness form an important basis of recommendations in public hea

54 e host IRF2, FAM111A, and RFC complex likely form an interaction network that influences the ability

55 Interestingly, the U3 and A6 bases form an intramolecular Hoogsteen base pair and directly

56 he first 4 ZFs, we observed that ZFs 3 and 4 form an unusual compact and stable structure that restri

57 on a radiological image of a human lung and forms an interactive resource for the scientific communi

58 tral for improved predictions of future reef form and function.

59 that exhibit ant-mimicking "myrmecoid" body forms and are behaviorally accepted into their aggressiv

60 ion, a parallel advance in understanding the forms and quantities of mitochondrial calcium stores is

61 omarkers were selected, including the parent forms and the major human metabolites of mephedrone, met

62 sfy regulatory requirements for nasal dosage forms and the polymer nanoparticles alone were found to

63 The accumulation of folate forms and their distribution varied among accessions.

64 rare highly penetrant mutations or sporadic forms - and holds promise as a biomarker for diagnosis a

65 structures, in addition to the volume of SOA formed, and an indicator of which of four oxidant precur

66 ng flies are protected by an air bubble that forms around their superhydrophobic cuticle upon enterin

67 elatively strong correlation validates tooth form as a proxy for neutral genomic markers.

68 approximately 3-27% present in the dissolved form as a result of iron binding by the organic exudate.

69 Magnetotactic bacteria form assemblies of magnetic nanoparticles called magneto

70 s down after transition into the low-density form at 130 K, but remains diffusive.

71 ion above zero degrees, because the unfolded form at low temperature is more expanded than the corres

72 ic Htt is present largely in a nonaggregated form at synapses, indicating that cytosolic forms of the

73 A "dome-shaped" profile can form at the upper boundary of the urban heat island circ

74 the substrate, an addition magnetic layer is formed at the interface whose properties are crucially i

75 detailed accounts of how negative images are formed at the level of synaptic plasticity rules, cells,

76 Neurons communicate with multiple targets by forming axonal branches.

77 Spore-forming bacteria are a class of microorganisms that poss

78 is dependent on whether SOA from limonene is formed before or during the formation of SOA from beta-p

79 ne is regulated by a cell type-specific loop formed between its promoter and the novel DRE.

80 ed spatially in the cell different complexes formed between RIG-I, TRIM25, and MAVS, in the presence

81 nsures interception since the bearing angle, formed between the line joining pursuer and target (call

82 intermediacy of heterodimer cation radicals formed between the stannane cation radicals and the neut

83 potassium channels (BK) are composed of pore-forming BKalpha and auxiliary beta1 subunits in arterial

84 nic esters react with 2-lithiated indoles to form boronate intermediates.

85 whereas their strongly destabilized mutants form both amyloids and nonamyloid aggregates.

86 The flattening of leaves to form broad blades is an important adaptation that maximi

87 Phytotelmata in tank-forming Bromeliaceae plants are regarded as potential mi

88 is first converted from a compact to linear form by flow, and is subsequently activated to bind GPIb

89 as primarily presented in its membrane-bound form by follicular dendritic cells.

90 so found a novel fusion involving USP9X-ERAS formed by chromothripsis and leading to high expression

91 s closed by a constriction of the inner pore formed by criss-crossing of the S6 segments at a conserv

92 tures 30 A-long surface protrusions that are formed by loops of the major capsid protein.

93 regular KMC jumps in trapping energy basins formed by neighboring tetrahedral interstitial sites, wi

94 Formed by oxidative oligomerization of catecholic small

95 of single-channel currents through the pore formed by recombinant ATOM40 were detected in electrophy

96 a sevenfold enhancement of the beta-hairpin formed by residues 27-31 and 33-38.

97 rtion of the alkene into a copper(I) hydride formed by reversible dissociation of HBpin from the copp

98 e the structure and morphology of aggregates formed by the P23T human gammaD-crystallin mutant associ

99 the basic structural motif of G-quadruplexes formed by, e.g., telomeric DNA sequences, but are also i

100 ts between these key residues are eventually formed can the protein reach the transition state and co

101 Self-assembling hMSCs formed cartilage discs in Transwell inserts following is

102 ma-inducible protein (IFI)16, bind dsDNA and form caspase-1-activating inflammasomes that are importa

103 of Ranvier and in axon initial segments, and form channel-transporter complexes in vitro and in vivo

104 Here we show that iron forms chemical bonds of similar strengths in basaltic gl

105 In cholesterol depleted membranes, PmB forms clusters on the membranes leading to an indentatio

106 two major protein variants: the centrosomal form (CnnC) and a non-centrosomal form in testes (CnnT).

107 cal immunoprecipitations indicated that TCTP forms complexes with Rad51 in vivo, and the stability ma

108 er species regulate meiotic DSB formation to form crossovers crucial for meiosis.

109 An effective method to form crystals is to introduce nucleation-inducing hetero

110 ntioselective hydroalkoxylation reaction and form cyclic ethers.

111 fast electron transfer within the triradical forms D(+*)-A-R(-), but its yield is controlled by spin

112 Enamel crystals form de novo in a rich extracellular environment in a st

113 the subsequent 17alpha,20-lyase reactions to form dehydroepiandrosterone (DHEA) and androstenedione (

114 CLEC3A mainly occurs as a monomer, but also forms dimers and trimers, potentially via a coiled-coil

115 thod utilizes RNA-functionalized AuNPs which form DNA-RNA heteroduplex structures through specific hy

116 r up to 1200 mum and irregular oblong shapes formed due to arrested coalescence during polymerization

117 Phagosomes form during engulfment of large particles and become inc

118 e first use of thiosemicarbazone exchange to form dynamic combinatorial libraries.

119 aureus and possibly other microorganisms and form EETs at sites of airway epithelial damage to protec

120 type CPMV containing RNA-2, and of naturally-formed empty CPMV capsids.

121 cific synthesis of, among others, eicosanoid-forming enzymes as well as relevant transcription factor

122 Ayu fish form feeding territories during a non-breeding (growing)

123 alternate proposal suggests that neovessels form from endothelial progenitors able to assemble the i

124 strained, horseshoe-shaped substrate pocket, formed from an alpha-helix, a 310 helix, and a recently

125 Cartilage formed from hMSCs remained stable and organized in vivo.

126 meticulously guided by transient structures formed from protein segments of low sequence complexity/

127 eneration of NHC-bound enolate intermediates formed from the ketoacids in the presence of the peptide

128 - or Z-N'-alkenyl urea, each of which may be formed from the same N-allyl precursor by stereodivergen

129 They can be formed from various Au sources.

130 ing heart function, but that loss of all Tln forms from the heart-muscle cell leads to myocyte instab

131 ained by balancing OC function with the bone-forming function of osteoblasts.

132 Guanine-rich oligonucleotides can form G-quadruplexes (G4), which are stabilized by the hy

133 ified in such projects as FANTOM and ENCODE, forming genome-wide landscapes in a series of human cell

134 d small-molecule surfactants) were guided to form hetero-vesicles, demonstrating the versatility of t

135 osphoprotein of human metapneumovirus (HMPV) forms homotetramers composed of a stable oligomerization

136 cells accumulated over time and persisted in forming hypertrophic-like scars, whereas few CD26-positi

137 lecules and to protein substrates in various forms, imposes a major challenge for these studies.

138 ro studies suggested OG would preferentially form in 5'-GG-3' sequence contexts after exposure to rea

139 entrosomal form (CnnC) and a non-centrosomal form in testes (CnnT).

140 N3-Methyladenine (3-MeA) is formed in DNA by reaction with S-adenosylmethionine, the

141 6-disubstituted 2-aminopyridine products are formed in moderate to high yields.

142 ansfer capable cytb 5 - cyt c complexes were formed in the presence of bicelles and nanodiscs.

143 preparation for the transition to the adult form, in which the AP axis converges on a molecular arch

144 s a disulfide-bonded heterodimer, whereas it forms inactive disulfide-bonded oligomers at neutral pH

145 also contain multiple cysteine residues that form intra- and interprotamine sulfur-sulfur bonds durin

146 react with proximal nucleophilic residues to form intra- or intermolecular protein crosslinks.

147 ejected even though most homologous pairings form irreversible products.

148 was immobilized employing insoluble La2O3 to form LaPO4.

149 les are formed, they may further nucleate to form larger polysulfur aerosols, thus providing a chemic

150 s, maneuver through extracellular matrix and form lasting inflammatory microstructures.

151 repetition learning task that simulates word-form learning.

152 hibit the same unimodal core coalignment but form local domains of microtubules polymerizing in the s

153 The beta-sheet self-assembles to form long fibrils with the hydrophobic edge and histidin

154 transmission of food preference (STFP), mice form long-term memory of food odors presented by a socia

155 low-frequency AC fields, long DNA molecules form macro-ion clusters.

156 it is retained during collapse of ruffles to form macropinosomes enriched for phosphatidylinositol 3,

157 Once formed, membrane permeability (integrity) was unaffected

158 ys primarily secrete two closely related gel-forming mucins, MUC5B and MUC5AC.

159 Gram-negative bacteria, some of these pumps form multi-protein assemblies that span the cell envelop

160 ggest that hkCP enhancers are more likely to form multi-TSS interaction networks and be associated wi

161 cate that FliG has a significant tendency to form multimers independently of other flagellar componen

162 R antagonists relieve depressive symptoms by forming new synapses resulting in increased excitatory d

163 Finally, we describe a novel form of activity-dependent intrinsic plasticity that per

164 invalidated hypothesis, and its use, in the form of ALARA dosing, is responsible for misguided conce

165 Finally, we consider the limitations of this form of analysis and the implications that this may have

166 d by singularities in cell alignments in the form of comet-shaped topological defects.

167 Such form of cross-over of stress may be beneficial if it enh

168 arsh parenting (smacking their children as a form of discipline).

169 normal visual experience leads to an extreme form of eye dominance, in which vision through the nondo

170 use the nuclease-based homing reaction as a form of gene drive to spread those genes through target

171 ne response play in the pathogenesis of this form of hepatic injury.

172 ordered proteins, resulting in a predominant form of iC3b that features high structural flexibility.

173 ole-cell K(+) currents produced by a mutated form of Kv2.1 mimicking apoptosis in a mammalian express

174 neuron and L7 are required to maintain each form of LTF.

175 B cells recognize epitopes on the dimerized form of LukAB during natural infection.

176 ejection (AMR) is an increasingly recognized form of lung rejection.

177 trix proteins and its dysfunction leads to a form of muscular dystrophy frequently associated with ne

178 Necroptosis, a programmed form of necrosis, is executed by the mixed lineage kinas

179 1 controls), the most severe and early onset form of periodontitis.

180 n ridge (MOR) spreading centers, both in the form of plume particles and seafloor massive sulfide str

181 d deposition of RNAPII-Ser5P, the initiating form of RNAPII, but no changes in H3K27me3, at the promo

182 d characteristic RPE-tears, another atypical form of RPE-defect with overlying preserved photorecepto

183 Leopards Panthera pardus exhibit a unique form of short-term food caching, regularly hoisting, sto

184 containing and embedding a microcrystalline form of sirolimus into the vessel wall.

185 lignant melanoma (MM) is the most aggressive form of skin cancer.

186 icate that SGPL1 mutations cause a syndromic form of SRNS.

187 tus epilepticus (SRSE) is a life-threatening form of status epilepticus that continues or recurs desp

188 ing this combination, we examined an amyloid form of Sup35NM that does not have a parallel in-registe

189 rdingly, exogenous expression of an inactive form of the 5-HT2C receptor in the locus ceruleus is ass

190 he refolding and incorporation of the normal form of the given protein.

191 tor-induced repression to generate an active form of the PIC.

192 s allosteric inhibitor AMP shows an inactive form of the tetramer, in which the dimer pairs are rotat

193 SA-15 bound exclusively to the dimeric form of the toxin, suggesting that human B cells recogni

194 eling experiments indicate that the dominant form of TMPRSS13 on the cell surface is phosphorylated,

195 Here, we considered the highest realistic form of VR: immersive videos.

196 n induce inflammation, resulting in multiple forms of brain toxicities.

197 e ability to recognize different crystalline forms of cellulose and chitin over a wide range of tempe

198 ostoperative cognitive dysfunction and other forms of cognitive decline related to immune-to-brain co

199 om the identification and study of inherited forms of early-onset AD and genetic risk factors that pr

200 crease of the phosphorylated, likely active, forms of FoxM1.

201 ique surface interactions for enabling novel forms of guided molecular assembly.

202 the FLNC variants were associated with mild forms of HCM and a reduced penetrance, with few affected

203 ications and therapeutic options for various forms of hydrocephalus and idiopathic intracranial hyper

204 Oocyte defects lie at the heart of some forms of infertility and could potentially be addressed

205 nts, which are crucial gatekeepers in common forms of intestinal cancer.

206 s can predict the occurrence of long-lasting forms of LTP for multiple experimental protocols.

207 nderlying the pathogenesis of most monogenic forms of NS, and to efficiently generate personalized in

208 hat overexpression of dominant-negative (DN) forms of NSF or knockdown of the expression of NSF, the

209 bar redness, compared with placebo, for both forms of omega-3 EFAs.

210 We show that short-term exposure to various forms of PE, displaying different molecular weight distr

211 The metastable uncapped forms of recapping targets redistribute from polysomes t

212 make or break electrical connections in new forms of reconfigurable nanocircuitry.

213 like stimulus when contrasted with all other forms of stimuli [6, 7].

214 truncated proviruses and expresses aberrant forms of the Gag protein.

215 ations of the dynamics in both apo- and holo-forms of the HCN4 isoform, reflecting how S672R remodels

216 ligand specificities of the human and murine forms of the myeloid C-type lectin receptor langerin for

217 form at synapses, indicating that cytosolic forms of the protein are likely to be the toxic species

218 on, toxicity is also associated with soluble forms of the proteins.

219 ng a valid tool for distinguishing different forms of these disorders in humans.

220 Exotic forms of these pure ices have been revealed at extreme (

221 rosecond MD simulations of different crystal forms of ubiquitin.

222 as also been implicated in mediating several forms of use-dependent plasticity, but the mechanisms by

223 n of CXCR4 observed in patients with various forms of WHIM syndrome.

224 also find that the combined effect of urban form on NO2 is larger for small cities (beta x IQR = -0.

225 ration is read as the length of colored band formed on the reaction was also demonstrated.

226 e Fe (oxyhydr)oxide rind, or Fe plaque, that forms on aquatic plant roots is an important sorbent of

227 Viruses represent the most abundant life forms on the planet.

228 ucture we refer to as the embryo sheath that forms on the surface of the embryo as it starts to elong

229 anus (Mucoromycotina) has been postulated to form part of the photosensory input for phototropism of

230 shelves, we have discovered that ponds often form part of widespread, large-scale surface drainage sy

231 ucture of muscle fibers and, along with DMD, forms part of the dystrophin-glycoprotein complex.

232 acid (MSA) reacts with amines and ammonia to form particles, which is expected to be particularly imp

233 Charged residues on the LBD surface form pathways that facilitate glutamate binding by effec

234 In this work, we create materials that form photoactivated depots of insulin without the need f

235 First, we report that UL8 alone forms protein filaments in solution.

236 pyruvate to CO2 in the T. brucei bloodstream form provides new support for the presence of an active

237 urther processed to the most active chemerin form, providing a molecular link between coagulation and

238 Fe-rich clay minerals such as nontronite can form rapidly under oxidized conditions, which could help

239 Sex-chromosomes have formed repeatedly across Diptera from ordinary autosomes

240 get genomic sequences by proximity ligation, forming RNA-DNA chimeric sequences, which are converted

241 These compounds crystallize to form robust open hydrogen-bonded networks with parallel

242 ration or humidification of an organic glass-forming sample result in stiffer mechanical properties,

243 ay be exploited to design other quasicrystal-forming self-assembly chemistries and processes.Probing

244 especially important when affecting habitat-forming species such as seagrasses, as the consequences

245 Although other CLC channels and transporters form stable dimers, ClC-4 was mostly observed as monomer

246 and amygdala neurons was stimulus-specific, formed stable attractors and was predictive of memory co

247 bstituted into zeolite *BEA, the metals that form stronger Lewis acids give greater selectivities and

248 (+)-Catechin is the flavanol prone to forming such pigments.

249 exible structure, particularly in the ferric form, such that it is able to sample a broad conformatio

250 Q), and Medical Outcomes Study 36-item Short Form Survey (SF-36) were obtained at enrollment and at 6

251 onal levels of VSG expression in bloodstream form T. brucei.

252 show evidence for the requirement of VASP to form tetramers and provide an amended model of processiv

253 core tetrameric HIV-1 STC and a higher-order form that adopts carboxyl-terminal domain rearrangements

254 A continuous siloxane network is formed that links together the muskeg, wood fibers, and

255 e latter reacting with ammonium molybdate to form the ammonium phosphomolybdate complex under acidic

256 d us to speculate as to whether our data may form the basis for a free radical substituent constant,

257 y, such specific fusion toxin proteins could form the basis of a therapeutic strategy for eliminating

258 kewise capable of multi-stimuli response can form the basis of programmable molecular systems, wherei

259 n a complex (I, initial), but if this cannot form the components show unrestricted and stochastic ass

260 s location, the alphaC fragment is unable to form the conserved catalytic interface that was thought

261 ture and composition, abnormalities of which form the direct, pathophysiologic substrate for SCD.

262 scicles of the right crus of diaphragm which form the esophageal hiatus are arranged like a "noose" a

263 mpacta and the ventral tegmental area, which form the nigrostriatal, mesolimbic, and mesocortical pat

264 the ribonucleoprotein particles (RNPs) that form the substrate for axonal translation.

265 eas reaction with the stronger oxidant AgBF4 formed the metal-free radical dication L(.2+) .

266 In contrast, the reaction of L(-) with CuI formed the unique, neutral Cu2 I2 (L(.) ) complex of a l

267 Forming the basis of this cost-efficient, label-free imm

268 Critical steps in forming the vertebrate limb include the positioning of d

269 This process forms the basis for the constant bearing angle (CBA) mod

270 us and organic solutions; the aqueous sample forms the central phase and is encompassed by two free l

271 e, as well as hyaluronic acid synthase which forms the disaccharide chain.

272 nd polyaxonal amacrine cells in mouse retina forms the synaptic mechanism responsible for long-range

273 decades and the structure of the cells that form them, denervated or repair Schwann cells, remains o

274 Once the Sn+1 particles are formed, they may further nucleate to form larger polysul

275 wells, the cells re-aggregated within hours, forming tight retinal organoids.

276 alled gp140, has also been made as a soluble form to mimic the native Env present on the virion surfa

277 nced aggregation potential and propensity to form toxic oligomers, they represent particularly attrac

278 ature with H2O in methanol/ether solution to form trans-[Pd(IPr)2(OH)(OOH)].

279 to replace JDP2 as a c-JUN binding partner, forming transcriptionally active AP-1.

280 ptide building block, which, by itself, only forms trimers and tetramers that do not replicate.

281 FtsZ monomers polymerize head to tail forming tubulin-like dynamic protofilaments, whose organ

282 PD-L1, E-cadherin, CD24, and VEGFR2 rapidly formed tumors outside the primary tumor microenvironment

283 tail pieces regenerate within about a week, forming two new worms.

284 ure and stability of the GSH-Cu(I) complexes formed under biologically relevant conditions remain con

285 wed by intramuscular injection of 108 plaque forming units of MVA-CMDR at weeks 12 and 24.

286 At death, as many as 10(10) colony-forming units were found in the lungs, spleen, and liver

287 However, circulating neutrophils form unstable aggregates and are unexpectedly primed to

288 copper(II) thiolate [Cu(II)]-SR intermediate formed upon reaction of an additional equiv thiol with [

289 oichiometric reaction at room temperature to form uranium(IV) siloxides.

290 es contain an isopropyl group proposed to be formed using CysS, a cobalamin-dependent radical S-adeno

291 Thus, SmI2(H2O)n should be able to form very weak C-H bonds.

292 Sparse lens materials form via low-valence linkages between disordered loops p

293 it is shown that SET/RESET programmed states form via the formation/annihilation of periodic van der

294 3 is also formed via H-atom abstraction from the corresponding mu-

295 nd tethers the ligand to misalign the QA and form weaker interactions with the aromatic groups.

296 er fire and/or have graminoid or herb growth forms were particularly affected by postfire weather, wh

297 stable analogue of the labile phosphorylated form) were identical and similar to the active state of

298 ype VAO, but predominantly in its protonated form when bound to the variants.

299 eugenol is predominantly in its deprotonated form when bound to wild-type VAO, but predominantly in i

300 Dimers formed when crystals were grown in the presence of the n