ライフサイエンスコーパス: formamide

1 it becomes that of bulk (in the presence of formamide).

2 equencing matrix (denaturing gels containing formamide).

3 buffers containing 7.2M urea plus 40% (v/v) formamide.

4 sport uncharged solutes such as glycerol and formamide.

5 odium, and chloride ions in liquid water and formamide.

6 s) and failed to grow on media containing 3% formamide.

7 dependence of the thermophoretic behavior of formamide.

8 ences lose their structure at less than 15 M formamide.

9 supercoiled DNA template in the presence of formamide.

10 oped by the dehydration of the corresponding formamide.

11 fy deleted loci that make cells sensitive to formamide.

12 e spectral signatures of the dimeric form of formamide.

13 tes isocyanides to yield the corresponding N-formamide.

14 op formation is increased in the presence of formamide.

15 t remove the resulting formyl group from the formamide.

16 2Se6](4-), and [GeSe4](4-) in both water and formamide.

17 ound to be strongly inhibited by substituted formamides.

18 of ethanol in mice was inhibited by several formamides.

19 series of cyclic, linear, and disubstituted formamides.

20 the preparation of optically active allylic formamides.

21 nservation of its tertiary structure in 20 M formamide?

22 16); (13)CH3NO2 (9, 19); N,N-dimethyl((13)C)formamide (10, 20); ((15)N)pyrrole (21, 23); CH3(15)NO2

23 was further identified as N-(4-methoxyphenyl)formamide 2-O-beta-D-xyloside and was revealed to have t

24 alyzed by N-methylvaline-derived Lewis-basic formamides 3a-d with high enantioselectivity (< or =95%

25 es): ((13)C)paraformaldehyde (1, 11); ((13)C)formamide (4, 14); triethyl ((13)C)orthoformate (5, 15);

26 We identified 4-O-beta-D-glucosyl-indol-3-yl formamide (4OGlcI3F) as a pathogen-inducible, tryptophan

27 nucleotide (ZMP) and N-(beta-D-ribofuranosyl)formamide 5'-phosphate (FAR-P) have been identified as p

28 The high degree of formamide accumulation is due to an unusual temperature

29 rogen from ammonium, nitrate, nitrite, urea, formamide/acetamide, purines, pyrimidines, polyamines, a

30 ey sequence features a highly chemoselective formamide activation that triggered a Vilsmeier-Haack cy

31 The prebiotic chemistry of formamide affords in a single and simple physical-chemic

32 n at 60 degrees C with buffer containing 50% formamide allow cells containing the LNA-bound mRNA to b

33 s on the use of polar solvents revealed that formamide also provided significant acceleration and the

34 for thioformamide substrates than for their formamide analogues.

35 ed by the N-methylvaline-derived Lewis basic formamide anchored to a polymeric support (5a and 5b) wi

36 served N-dealkylation, and to the identified formamide and aldehyde derivatives via several intermedi

37 hich are formed in a direct reaction between formamide and CN(*) radicals upon the high-energy impact

38 looping remains elusive, FRET experiments in formamide and dimethyl sulfoxide suggest that interactio

39 and commonly used denaturing agents such as formamide and DMSO.

40 mines 32-33 were obtained in two steps using formamide and hydrazine, respectively.

41 our results indicate a similar stability of formamide and hydrogen cyanide in solution as well as th

42 the hydrolysis of N-formimino-L-glutamate to formamide and L-glutamate.

43 n of gDNA with NaOH is instead achieved with formamide and maintains denaturation during subsequent s

44 barrier from amide hydrogen bonding between formamide and N(6) of adenine.

45 The products of this reaction, N-formamide and N,N'-diformamide, are hydrogenated back to

46 tone-d(6) showed a slight deviation, whereas formamide and pyridine-d(5) exhibited distinctly differe

47 on the amidation of esters with mixtures of formamide and sodium methoxide are described.

48 tic resolution of amine derivatives based on formamide and thioformamide substrates.

49 address these issues, we decided to focus on formamide and undertook an extensive study of low molecu

50 The gel solvent included formamide and urea.

51 pling of amines with MeOH and EtOH affording formamides and acetamides.

52 bamoyl anions derived from N,N-disubstituted formamides and LDA to N-tert-butyl nitrones is described

53 oyl anions, generated from N,N-disubstituted formamides and lithium diisopropylamide, add with high d

54 reaction was demonstrated with a variety of formamides and nitrones and provided a direct route to a

55 g copper-catalyzed oxidative C-O coupling of formamides and salicylaldehydes.

56 aluated ethylene glycol, dimethyl formamide, formamide, and methanol for their freezing point suppres

57 it was found that methanol, triethanolamine, formamide, and water all provided additional acceleratio

58 this study that retains so much structure in formamide; and (c) DNA analogs of formamide resistant HD

59 pore organization, whereas those prepared in formamide are long-range ordered with hexagonal symmetry

60 oton transfers from the 5-amino group to the formamide are simultaneous with nucleophilic attack by t

61 Formamides are aldehyde analogues that have demonstrated

62 st, the linear, alkyl (n-propyl and n-butyl) formamides are better inhibitors of EqADH and MmADH1 tha

63 Monosubstituted formamides are good inhibitors of class I and II enzymes

64 of class I and II enzymes, and disubstituted formamides are selective for the alpha enzyme.

65 Formamides are unreactive analogues of aldehydes and bin

66 Formamides are unreactive analogues of the aldehyde subs

67 erimental and theoretical evidence points to formamide as a possible hub in the complex network of pr

68 sulfoxide, polyethylene glycol, betaine and formamide as cosolvents has been found to be very helpfu

69 s switched on and identifies formic acid and formamide as key intermediate products of the early step

70 aqueous solution of LaCl3.7H2O with N-methyl formamide as porogen and propylene oxide as initiator.

71 water permeability but transported glycerol, formamide, as well as larger solutes that were impermeab

72 sured for the urease-catalyzed hydrolysis of formamide at pH 6.0 and 25 degrees C.

73 demonstrated a high degree of reliability of formamide-based denaturation and bisulfite conversion th

74 This formamide-based method was applied to 46 formalin-fixed/

75 The formamide-based synthesis of nucleic acids is considered

76 rcury-sensitive permeability to glycerol and formamide, but not urea, suggesting that NOD 26 also flu

77 ation and decomposition reaction channels of formamide by means of ab initio molecular dynamics.

78 and trimethylaluminum efficiently activates formamide C-H bonds under mild conditions providing pyrr

79 f DNAs linearly by 2.4-2.9 degrees C/mole of formamide (C(F)) depending on the (G+C) composition, hel

80 including incubation at 95 degrees C in 50% formamide can be used without disrupting the streptavidi

81 s such as N-Boc-amines and the parent chiral formamide compounds.

82 pression], exhibits a biphasic dependence on formamide concentration.

83 The initial drop of -0.8 kcal/mol bp at low formamide concentrations is attributable to a delta delt

84 Thus, we suggest the possibility that formamide could have jointly provided the main component

85 ammonium formate is produced as an important formamide decomposition byproduct in solution.

86 offering an alternative to the conventional formamide dehydration route.

87 Subsequent treatment with HCl yielded free formamide, demonstrating that an important organic molec

88 The current article features novel use of formamide denaturant during bisulfite conversion of a su

89 ed size of the expanded adenine, we tested a formamide deoxynucleoside, which Leonard proposed as a s

90 binding domain of streptococcal protein G, a formamide dimer was generated from the crystallographic

91 Justification for the use of formamide dimers is provided by almost identical interre

92 C) contributions to interresidue coupling in formamide dimers with systematic variation of these stru

93 (dA.dT) exhibits a much lower sensitivity to formamide, due to the specific pattern of tightly bound,

94 ects were measured at the reactive center of formamide during acid-catalyzed hydrolysis in water at 2

95 he high-energy synthesis of nucleobases from formamide during the impact of an extraterrestrial body.

96 s, including guanidine thiocyanate, ethanol, formamide, ethylenediaminetetraacetic acid (EDTA), and p

97 The results in three organic solvents, formamide (FA), N-methylformamide (NMF), and N,N-dimethy

98 ds by formal C-H bond cleavage of an allylic formamide followed by construction of a new C-C bond in

99 are consistent with a fast deprotonation of formamide followed by two reversible acyl transfers affe

100 We evaluated ethylene glycol, dimethyl formamide, formamide, and methanol for their freezing po

101 The use of formamide further improved the performance of the new pr

102 Using formamide, further acceleration was achieved in the pres

103 ore frequently with V114 and F193, while its formamide group interacted more frequently with C191.

104 el to the fifth transmembrane helix with the formamide group of fMLF hydrogen-bonded to both Asp-106

105 The lability of the formamide group required that nucleoside triphosphate fo

106 Results indicate that formamide has a destabilizing effect on the helical stat

107 Liquid formamide has been irradiated by high-energy proton beam

108 ctrospray ionization compatibility; however, formamide has potential to be a superior modifier if det

109 Mineral-assisted thermal decomposition of formamide (HCONH(2)) is a heavily studied model prebioti

110 enatured DNA, the cosolvent condition of 40% formamide hydration is very different: it becomes that o

111 e identification and characterization of the formamide hydrolase that catalyzes the second step in th

112 ve found that the spectrum of the evaporated formamide ices is dominated by the spectral signatures o

113 , we scrutinized the chemical composition of formamide ices mixed with an FeNi meteorite material tre

114 The electronic spectrum of formamide in aqueous solution is computed using TDDFT us

115 Furthermore, use of formamide in the ligation buffer also increased ligation

116 ding aldehydes, ketones, formate esters, and formamides, in an overall process that efficiently conve

117 Formamide-induced detubulation of rat ventricular myocyt

118 vity for this unique isoenzyme of any of the formamide inhibitors.

119 h small aliphatic isonitriles to form N-acyl formamides inside the cavity.

120 The pH optimum for formamide is at pH 5.3, whereas for urea, it is near 8.0

121 Formamide is one of the important compounds from which p

122 t acyl transfer between the ester and sodium formamide is rate-determining.

123 onization mass spectrometry (CI-TOFMS) where formamide, isocyanic acid as well as higher order produc

124 Formamide lowers melting temperatures (Tm) of DNAs linea

125 enine stabilizing the E configuration of the formamide moiety is also observed for the AFB-beta-FAPY

126 adenine stabilizes the E conformation of the formamide moiety.

127 Y C5-N(5) bond and the E conformation of the formamide moiety.

128 nstrate that the initial dissociation of the formamide molecule could produce a large amount of highl

129 ttachment of the nucleophile to a protonated formamide molecule is rate determining.

130 A formamide molecule was modeled into the system to mimic

131 We report gas-phase electronic spectra of formamide, N-methyformamide, acetamide, and N-methylacet

132 n the vicinity of the helix: displacement by formamide of weakly bound hydrate or counterion.

133 t of an extraterrestrial icy body containing formamide on an early Earth atmosphere.

134 icant acceleration and the use of 5 equiv of formamide (optimum amount) gave faster rates than reacti

135 roduct RNAs are structured to 24 M (95% w/w) formamide or 4 M H2O solutions which is equivalent to 4

136 Clear(T) or Clear(T2), which are composed of formamide or formamide/polyethylene glycol, respectively

137 conditions or in solvents, such as dimethyl formamide or N-methylpyrrolidone, to provide the desired

138 ygen from the solvent into the carbonyl-O of formamide or the product, formate ion.

139 sary as the carbon is trapped in the form of formamide (or urea in the case of primary amine).

140 l and [DMF.H(+)](CF3SO3(-))) (DMF = dimethyl-formamide) or electron (decamethylferrocene (Fc*)) sourc

141 vironmentally benign solvents such as water, formamide, or dimethylsulfoxide.

142 elative to the controls (no radiation, or no formamide, or no catalyst), an extremely rich, variegate

143 s but observed no effect on water, glycerol, formamide, or urea permeations.

144 dentical model compounds: N-methylacetamide, formamide, or water.

145 ic pathways indicate that small radicals and formamide play a crucial role, in agreement with a numbe

146 lear(T2), which are composed of formamide or formamide/polyethylene glycol, respectively, embryos, wh

147 We conclude that formamide preferentially targets RNA related processes i

148 In this study, we have found that formamide preferentially weakens RNA related processes i

149 amino group through the 4-carboxamide to the formamide proceeds in the same transition state.

150 Substituted acetic acids and formamides react in the presence of phosphorus oxychlori

151 insight into the interplay of the different formamide reaction channels and into environment effects

152 most efforts have focused on the analysis of formamide reaction products released in solution, althou

153 w coating medium, N-(2-triethoxysilylpropyl) formamide, recently demonstrated by our laboratory to ne

154 detubulation (by transient exposure to 1.5 m formamide) reduces global acid extrusion on NBC by 40%,

155 ereoselective epoxidation followed by a mild formamide reduction enabled the first total synthesis of

156 ructure in formamide; and (c) DNA analogs of formamide resistant HDV ribozyme sequences lose their st

157 Crystalline FAIRs exists solely as the Z-formamide rotamer and exhibits many of the same intramol

158 d by the N-methyl valine-derived Lewis-basic formamide (S)-23 (Sigamide) with high enantioselectivity

159 port growth at 37 degrees C and one was also formamide sensitive (fs) and failed to grow on media con

160 In addition, we have also isolated 35 formamide-sensitive mutants, many of which display remar

161 RSC6 also suppressed the formamide sensitivity of a strain with a C-terminal trun

162 t, its disruption results in slow growth and formamide sensitivity.

163 g reaction of these ionic building blocks in formamide solution results in spontaneous gelation and e

164 The thermophoretic properties of aqueous formamide solutions are studied by means of Infrared The

165 eptylammonium bromide clusters produced from formamide solutions by electrospray ionization (ESI) is

166 We followed the ribozyme structure in formamide solutions by monitoring the amount of bound Et

167 of multiple building units both in water and formamide solutions favors the assembly of mesostructure

168 HDV) ribozyme self-cleaving activity in 20 M formamide solutions is unique.

169 and saturates to highly concentrated aqueous formamide solutions of approximately 85 wt% at large asp

170 metastable polymorph, a hydrate phase, and a formamide solvate.

171 In general, larger, substituted formamides, such as N-1-ethylheptylformamide, are better

172 Some small formamides, such as N-isopropylformamide, may be useful

173 In formamide the [SnQ4]4- anions undergo condensation-oligo

174 data from the urease-catalyzed hydrolysis of formamide, the commitment factors for semicarbazide and

175 for the anionic form of the sulfhydryl; for formamide, the neutral form is preferred, leading to the

176 ylamide gel contained 3.36 M urea and 19.2 % formamide to lower the DNA melting temperatures.

177 NH radicals, which could further react with formamide to produce adenine, guanine, cytosine, and ura

178 ide (DMSO), betaine, polyethylene glycol and formamide, to the reaction mixture.

179 hydrothermal pores leads to accumulation of formamide up to concentrations where nucleobases are for

180 f 5-amino-4-carboxamide imidazole (AICA) and formamide using the B3LYP/6-31G level of theory confirme

181 The pKa for formamide was determined by 15N NMR and found to be abou

182 egeneration solutions; mix of 25 mM NaOH/30% formamide was employed to regenerate the electrode for a

183 Formamide was found to be a superior solvent for obtaini

184 at 454 nm), and chlorophyll a aggregates in formamide/water (rho(v)(90) = 0.23 and 0.32 at 469 and 6

185 ched after 45-90 d, starting with an initial formamide weight fraction of[Formula: see text]wt % that

186 Superelectrophiles: Formamides were designed that when treated with triflic

187 Fourteen new branched chain and chiral formamides were prepared and tested as inhibitors of pur

188 ectivity of the assay was achieved using 20% formamide, which allowed discrimination between a fully

189 w coating medium, N-(2-triethoxysilylpropyl) formamide, which has been shown to diminish electroosmot

190 r three additional substrates: N-(2-propenyl)formamide, (Z)-3-formamido-2-butenenitrile, and (E)-3-fo