ライフサイエンスコーパス: formyl

1 n/ion-mediated peptide derivatization with 4-formyl-1,3-benezenedisulfonic acid (FBDSA) anions using

2 es with a second population of chromogenic 4-formyl-1,3-benzenedisulfonic acid (FBDSA) anions to prom

3 ion/ion reactions with doubly deprotonated 4-formyl-1,3-benzenedisulfonic acid (FBDSA) in the gas-pha

4 le 4-bromo-2-triisopropylsilyloxyfuran and 2-formyl-1,3-dithiane.

5 2-methoxycarbonyl-, 2-aminocarbonyl-, and 2-formyl-1,4-benzodioxane, are key synthons that for the m

6 , 5-hydroxymethyl-2'-deoxycytidine (hmdC), 5-formyl-2'-deoxycytidine (fdC) and 5-carboxy-2'-deoxycyti

7 e normal one from the tumor's margin; also 5-formyl-2'-deoxycytidine and 5-carboxy-2'-deoxycytidine w

8 idine, 5-(hydroxymethyl)-2'-deoxycytidine, 5-formyl-2'-deoxycytidine, 5-carboxy-2'-deoxycytidine, 5-(

9 ificantly lower yields of products such as 5-formyl-2'-deoxyuridine that are ascribable to deprotonat

10 The 3-formyl-2-furylcarbinols are further elaborated in two st

11 fficiently provide, in one step, access to 3-formyl-2-furylcarbinols, which are otherwise only access

12 ones (2-pyridone, 3-chloro-2-pyridone, and 3-formyl-2-pyridone) have been examined in the gas phase u

13 nm range induced direct transformation of 2-formyl-2H-azirine into 3-formylketenimine; (ii) irradiat

14 found to isomerize into several products: 2-formyl-2H-azirine, 3-formylketenimine, 3-hydroxypropenen

15 Treatment of 3,5-diformyl BODIPYs or alpha-formyl 3-pyrrolyl BODIPY with different alkyl/aryl ylide

16 ure of ATI-5261 to acrolein resulted in N-(3-formyl-3,4-dehydropiperidino) (FDP)-lysine adducts at po

17 rimidinamine dihydrochloride), and KNK437 (N-Formyl-3,4-methylenedioxy-benzylidine-gamma-butyrolactam

18 A-EDA [2-(3,4-hydroxyphenyl) ethyl (3S,4E)-4-formyl-3-(2-oxoethyl)hex-4-enoate], starting from natura

19 ochalcogen compounds derived from 2-chloro-1-formyl-3-hydroxymethylenecyclohexene (16) are described.

20 roscopy and a sensing ensemble composed of 2-formyl-3-hydroxypyridine (4) and Fe(II)(TfO)(2).

21 cles having Pt(IV) ion were prepared from (4-Formyl-3-methoxyphenoxymethyl) polystyren, glycine and P

22 prepared using the nanoparticles modified (4-Formyl-3-methoxyphenoxymethyl) with polystyren (FMPS) wi

23 1-(3'-Formyl-4'-hydroxyphenyl)-8-(9'-anthryl)naphthalene (1) w

24 1-(3'-Formyl-4'-methoxyphenyl)-8-(4'-isoquinolyl)naphthalene N

25 and 12 led to the formation of (Z)-1,2-bis(2-formyl-4-((2E)-1-methylbut-2-en-1-yl)phenyl)diazene-1-ox

26 sette transporter system ThiXYZ transports N-formyl-4-amino-5-(aminomethyl)-2-methylpyrimidine (FAMP)

27 aldehyde functionalized ionic liquid, (3-(3-formyl-4-hydroxybenzyl)-3-methylimidazolium hexafluoroph

28 1, 2-formyl-5-(2-methoxyphenyl)-pyrrole, which was weakly cor

29 )-l-tryptophan (ARP), Tryptophol (TRO), 2-(2-formyl-5-(hydroxymethyl-1H-pyrrole-1-yl)butanoic acid (P

30 -hydroxymelatonin [6(OH)M], N(1)-acetyl-N(2)-formyl-5-methoxykynuramine (AFMK) and 5-methoxytryptamin

31 es: 6-hydroxymelatonin (6-OHM), N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK), N-acetylserotonin (NA

32 r oxidation to the 5-hydroxymethyl (5hmC), 5-formyl (5fC), or 5-carboxyl (5caC) forms.

33 d to the concise synthesis of glycozoline, 3-formyl-6-methoxy-carbazole, and 6-methoxy-carbazole-3-me

34 chemical screen and identified 4-[(2Z)-2-[4-formyl-6-methyl-5-oxo-3-(phosphonatooxymethyl)pyridin-2-

35 iously-reported low-spin Fe(II)4L4 cage 2: 2-formyl-6-methylpyridine was ejected in favor of the less

36 ect of 1.8 on the imine reduction to preQ1 7-Formyl-7-deazaguanine, a carbonyl analogue of the imine

37 nd its function was evaluated in AMs using 8-formyl-7-hydroxy-4-methylcoumarin (4mu8C), an inhibitor

38 The reaction between substituted 1-formyl-9H-beta-carbolines and terminal alkynes in the pr

39 clocondensation of beta-ketosulfones 1 and o-formyl allylbenzenes 2 provides sulfonyl oxabenzo[3.3.1]

40 on, as well as methodologies to modify the N-formyl amide of the resultant cycloaddition product, are

41 ion between the two carbonyl groups of the N-formyl amide.

42 inetic resolutions of alpha-stereogenic-beta-formyl amides in asymmetric 2-aza-Cope rearrangements ar

43 thro-pentafuranosyl)-2,6-diamino-4-hydroxy-5-formyl amidopyrimidine (Fapy-dG), is associated with pro

44 The limit of detection (LOD) for N-formyl amphetamine was determined to be 10muM in this ca

45 -mdC) in DNA to yield the 5-hydroxymethyl, 5-formyl and 5-carboxyl derivatives of 2'-deoxycytidine (5

46 With DMF, abstraction occurs from the formyl and N-methyl C-H bonds, with the formyl being the

47 the formyl and N-methyl C-H bonds, with the formyl being the preferred abstraction site, as indicate

48 The method uses thermally stable 4-formyl benzamide functionalized (4FB) magnetic beads rat

49 acid (TFA) results in peptides that have a 4-formyl-benzamido group where the nitro group used to be.

50 nstruction and retention of enolizable alpha-formyl benzylic stereocenters, a valuable synthon for th

51 Enantiopure 4-formyl-beta-lactams were deployed as synthons for the di

52 ions afford the substituted cis-1-hydroxyl-8-formyl-bicyclo[4,3,0]non-8(9)-enes or bicycle[4,3,0]non-

53 e identify a reactive pathway in amides, the formyl C-H abstraction, not currently considered in stru

54 ormamides HAT preferentially occurs from the formyl C-H bond, while in N-formylpyrrolidine HAT mostly

55 ations with hydrocarbon lengths ranging from formyl (C1) to palmitoyl (C16) as well as negatively cha

56 with additional functional handles, such as formyl, chloromethylketone, and iodide.

57 of a tetraglycine loop in the active site of formyl-CoA:oxalate CoA transferase (FRC) play an importa

58 The enzymes YfdW, a formyl coenzyme A (CoA) transferase, and YfdU, an oxalyl

59 The rhodium formyl complex ((tmtaa)Rh-C(O)H) was isolated under a CO

60 m equilibrium distributions with hydride and formyl complexes ((tmtaa)Rh-H (2); (tmtaa)Rh-C(O)H (3)).

61 reactions of (tmtaa)Rh-H with CO to produce formyl complexes in toluene (K2(298 K)(tol) = 10.8 (1.0)

62 Eleven formyl-containing BODIPY dyes were prepared by means of

63 hydroxymethyl dihydroxypyrrolidines from C-2 formyl D-glycals has been described via a common dicarbo

64 The best substrates for this enzyme are N-formyl-d-glutamate (k(cat)/K(m) = 5.8 x 10(6) M(-1) s(-1

65 ries containing nearly all combinations of N-formyl-d-Xaa, N-acetyl-d-Xaa, N-succinyl-d-Xaa, and l-Xa

66 5-Formyl-dC (fdC) and 5-carboxy-dC (cadC) are newly discov

67 the stoichiometric reduction of CO to give a formyl derivative which reacts further via an epoxy-bora

68 3-H4folate, followed by a plateau due to the formyl derivatives and minor compounds stability.

69 The conjugate addition of N-formyl derivatives of 2-amino-3-iodo- and 3-amino-4-iodo

70 hermal treatment, with a better retention of formyl derivatives.

71 key equilibration of a formyl imine to an N-formyl enamine.

72 size a BODIPY dimer by McMurry coupling of a formyl Et2B-BODIPY, while a new BODIPY with an asymmetri

73 ate to 8-amino-FMN via the intermediacy of 8-formyl-FMN.

74 hat ethanol synthesis on Rh(111) starts with formyl formation from CO hydrogenation, followed by subs

75 The azaBODIPYs containing one and two formyl functional groups on the 1,7-aryl groups present

76 of N-formyl-protected glycine as the ligand (Formyl-Gly-OH) was crucial for the development of this r

77 recombinantly overexpressed AT retains the N-formyl group (fAT), presumably due to incomplete N-formy

78 eliver 2,4-cyclohexadienones featuring a key formyl group and a quaternized carbon atom in good yield

79 etic version that features the transfer of a formyl group and hydride from an aldehyde substrate to a

80 A hydrogen bond between the formyl group and the exocyclic amine of the 3'-neighbor

81 n the B ring of a tetrapyrrole molecule to a formyl group by chlorophyllide a oxygenase (CAO).

82 We found that the 5-formyl group could increase duplex thermal stability and

83 enzyme that is responsible for removing the formyl group from nascently synthesized polypeptides in

84 ing of GTP but does not remove the resulting formyl group from the formamide.

85 of the chlorophylls and the formation of the formyl group in Chl f.

86 Our results showed that the 5-formyl group is located in the same plane as the cytosin

87 However, the biochemical provenance of this formyl group is unknown.

88 because the hydroxymethyl group of 5hmC and formyl group of 5fC adopt restrained conformations throu

89 the methyl group of BChlide c or d into the formyl group of BChlide e or f This probably occurs by a

90 d (2)H) to determine the origin of the C2(1)-formyl group of Chl f and to verify whether Chl f is syn

91 the multidomain protein, HypX, converts the formyl group of N(10)-CHO-THF into water and CO, thereby

92 A structure-activity study showed that the formyl group on position 1 and the bromine atom on posit

93 We found that the oxygen atom of the C2(1)-formyl group originates from molecular oxygen and not fr

94 atharanthine N-methyl group or a vindoline N-formyl group precludes Fe(III)-promoted coupling, wherea

95 hifted absorption maximum because of a C2(1)-formyl group substitution of Chl f However, the biochemi

96 Formyl group substitutions on the side chains of chlorop

97 construction of pyrroles bearing a 2-keto or formyl group through the intramolecular oxidative aza-an

98 ophorbine skeleton and bears a 7-methyl or 7-formyl group, respectively.

99 s to novel polycyclic scaffolds decorated by formyl groups and carboxylates suitable for subsequent m

100 CH...O hydrogen bonds involving formyl groups have been invoked as a crucial factor cont

101 The formyl-H KIEs are (D)k = 0.80 in 200 mM HCl, (D)k = 0.77

102 Solvent (D2O) and secondary formyl-H kinetic isotope effects (KIEs) were measured by

103 oxygen of the boronate and is oriented by a formyl hydrogen bond (Goodman model) and by other electr

104 H...O hydrogen bond and the secondary CH...O formyl hydrogen bond as the reaction occurs.

105 The strength of the formyl hydrogen bond in the TS, a second CH...O interact

106 the phosphoryl oxygen of the catalyst to the formyl hydrogen of the aldehyde.

107 ith CuCN catalyzing a key equilibration of a formyl imine to an N-formyl enamine.

108 end of an O-bound CO, which forms an eta(2)-formyl intermediate that adds, in a second step, the bor

109 ring cleavage reaction of L-tryptophan to N-formyl kynurenine, the initial and rate-limiting step of

110 (2)-dependent oxidation of L-tryptophan to N-formyl-kynurenine.

111 ethynyl)-pyridine], the DGL inhibitor THL [N-formyl-l-leucine (1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetan

112 C reduction in the presence and absence of N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP) (1 mu

113 ecylmaltoside extracts of unstimulated and N-formyl-Met-Leu-Phe (fMLF) + cytochalasin B-stimulated ne

114 ted in impaired chemotactic migration toward formyl-Met-Leu-Phe (fMLP) and stromal cell-derived facto

115 horylated in response to the chemoattractant formyl-Met-Leu-Phe (fMLP) in adherent cells.

116 as studied here using the bacterial peptide, formyl-Met-Leu-Phe (fMLP), as an RB inducer.

117 after exposure to chemoattractants such as N-formyl-Met-Leu-Phe (fMLP).

118 Both commensal bacteria and N-formyl-Met-Leu-Phe application to the apical surface of

119 Sensing of N-formyl-Met-Leu-Phe by gut epithelial cells occurs via re

120 entraxin 3 and induced the apoptosis of both formyl-Met-Leu-Phe or LPS-activated neutrophils and LPS-

121 nesis, polarization, chemotaxis, and FMLP (N-formyl-met-leu-phe)-induced actin assembly.

122 vation was recapitulated using the peptide N-formyl-Met-Leu-Phe, a bacterial product known to stimula

123 ainst a bacterially derived chemoattractant (formyl-met-leu-phe, fMLP), with and without preactivatio

124 s rhamnosus GG and the FPR peptide ligand, N-formyl-Met-Leu-Phe, was abolished in the presence of sel

125 e seen for the natural chemotactic peptide n-formyl-Met-Leu-Phe.

126 th cotranslational removal of the N-terminal formyl methionine.

127 cteria, plants, and humans that remove the N-formyl-methionine off peptides in vitro.

128 group (fAT), presumably due to incomplete N-formyl-methionine processing by peptide deformylase.

129 the ability of the peptide chemoattractant N-formyl-methionine-leucine-phenylalanine (fMLF) to activa

130 Chemotaxis to N-formyl-methionine-leucine-phenylalanine by freshly isola

131 -mediated intermediary chemotaxis, whereas N-formyl-methionine-leucine-phenylalanine receptor-mediate

132 actin to filamentous actin in response to N-formyl-methionine-leucine-phenylalanine, resulting in si

133 microsources loaded with the chemoattractant formyl-methionine-leucine-phenylalanine.

134 and basophil HR in response to anti-IgE and formyl-methionine-leucine-phenylalanine.

135 th proteins retain the N-terminal initiating formyl-methionines.

136 lk of the 50S, and on its deletion, proper N-formyl-methionyl(fMet)-tRNA(fMet) positioning and effici

137 wever, P. stomatis significantly increased N-formyl-methionyl-leucyl phenylalanine (fMLF)-stimulated

138 activity of alphaMbeta2 integrin following N-formyl-methionyl-leucyl phenylalanine stimulation.

139 inophil responsiveness upon stimulation with formyl-methionyl-leucyl phenylalanine was found to ident

140 LAgP PMNs before and after stimulation with formyl-methionyl-leucyl-phenylalanine (100 nM).

141 e of superoxide elicited by phorbol ester or formyl-methionyl-leucyl-phenylalanine (fMLF) was unaffec

142 eceptor (FPR) on neutrophils, which binds to formyl-methionyl-leucyl-phenylalanine (fMLP) and plays a

143 nases (MAPK)] were assessed in response to N-formyl-methionyl-leucyl-phenylalanine (fMLP) stimulation

144 Secondary stimulation of PMNs with 1 muM N-formyl-methionyl-leucyl-phenylalanine (fMLP) triggered e

145 When neutrophils were exposed to formyl-methionyl-leucyl-phenylalanine (fMLP), PKCbetaII

146 receptor in the CNS, and also reduces the N-formyl-methionyl-leucyl-phenylalanine (fMLP)-induced neu

147 lpha, was used to examine the mechanism of N-formyl-methionyl-leucyl-phenylalanine (fMLP)-mediated fo

148 13, in basophils stimulated with anti-IgE, N-formyl-methionyl-leucyl-phenylalanine, or phorbol 12-myr

149 suppressed basophil activation induced by N-formyl-methionyl-leucyl-phenylalanine, phorbol 12-myrist

150 LA(2)-X to eosinophils under conditions of N-formyl-methionyl-leucyl-phenylalanine-mediated cPLA(2)al

151 ation in the presence of the chemoattractant formyl-methionyl-leucyl-phenylalanine.

152 tion containing beta-lysyl-EF-P stimulated N-formyl-methionyl-puromycin synthesis approximately 4-fol

153 S initiation complexes (ICs) that carry an N-formyl-methionyl-tRNA (fMet-tRNA(fMet)).

154 some along with the initiator transfer RNA N-formyl-methionyl-tRNA(i) (fMet-tRNA(i)(fMet)) and a shor

155 d for the preparation of 3,5-disubstituted 4-formyl-N-arylpyrazoles in a one-pot procedure is reporte

156 Competition binding using FPR1 ligands N-formyl-Nle-Leu-Phe-Nle-Tyr-Lys (Nle = Norleucine), formy

157 aturation binding with fluorescein-labeled N-formyl-Nle-Leu-Phe-Nle-Tyr-Lys revealed ~2500 specific b

158 othesis, propofol inhibited the binding of N-formyl-Nle-Leu-Phe-Nle-Tyr-Lys-fluorescein, a fluorescen

159 l protocol for the direct formation of alpha-formyl olefins employing common building blocks for orga

160 Bromo intermediates bearing formyl or trifluoroacetyl were prepared by monolithiatio

161 e analogues contain a 7-substituent (acetyl, formyl, or TIPS-ethynyl), a 10-mesityl group, and the 18

162 es is replaced with methyl-, hydroxymethyl-, formyl-, or carboxylcytosine.

163 an iridium-based catalyst designed to favor formyl over aromatic C-H activation.

164 N-Formyl peptide (fMLF) receptors (FPRs) are chemotactic r

165 at inflammation sites is partly driven by N-formyl peptide chemoattractant receptors (FPRs).

166 calcium store release with U73122, abrogated formyl peptide induced calcium elevation, and delayed su

167 emotaxis, suggesting that this peptide binds formyl peptide receptor (FPR) 2.

168 PSMs exert their function by binding to the formyl peptide receptor (FPR) 2.

169 an endogenous anti-inflammatory circuit via formyl peptide receptor (FPR) 2/lipoxin receptor (ALX) (

170 The formyl peptide receptor (Fpr) family is well known for i

171 G protein-coupled receptor belonging to the formyl peptide receptor (FPR) family, conveys the biolog

172 O receptors comprising 5 of 7 members of the formyl peptide receptor (FPR) family.

173 eptide, cFLFLFK-PEG-(64)Cu, that targets the formyl peptide receptor (FPR) on leukocytes is described

174 The formyl peptide receptor (FPR) on neutrophils, which bind

175 E neutrophils in a dose-dependent manner via formyl peptide receptor (FPR) stimulation.

176 The specific role of the high affinity formyl peptide receptor (FPR) was then tested using spec

177 Our investigation of formyl peptide receptor (FPR)-mediated chemotaxis reveal

178 -37pA induces calcium and chemotaxis through formyl peptide receptor (FPR)2/ALX, whereas its D-stereo

179 N-formyl peptide receptor (FPR1) and N-formyl peptide rece

180 15-epi-LXA4 activated formyl peptide receptor (FPR2) and GPR120 on alternative

181 Our results demonstrate that formyl peptide receptor 1 (FPR1) and neutrophilic NADPH

182 Cys549, which then induces TRMP2 binding to formyl peptide receptor 1 (FPR1) and subsequent FPR1 int

183 Binding of formyl peptide receptor 1 (FPR1) by N-formyl peptides ca

184 Formyl peptide receptor 1 (FPR1) is a G protein-coupled

185 ceptor to be described on human neutrophils, formyl peptide receptor 1 (FPR1), is one such receptor t

186 osis by CXC chemokine receptor 2 (CXCR2) and formyl peptide receptor 1 (FPR1), respectively.

187 ted from wild-type mice and mice lacking the formyl peptide receptor 1, we demonstrate that LTB(4) ac

188 Activation of the G-protein coupled formyl peptide receptor 2 (ALX/FPR2) by the lipid mediat

189 Formyl peptide receptor 2 (FPR2) emerges as a central re

190 Formyl peptide receptor 2 (FPR2) is a chemoattractant re

191 Neutrophils expressing formyl peptide receptor 2 (FPR2) play key roles in host

192 Selective agonists and antagonists of formyl peptide receptor 2 (Fpr2) suggested that Fpr2 med

193 timization of a peptidomimetic antagonist of formyl peptide receptor 2 (FPR2) was explored by an appr

194 Formyl peptide receptor 2 (FPR2), a classical chemoattra

195 Here we report that formyl peptide receptor 2 (Fpr2/3) null mice display a m

196 ding and activation of the human and mouse N-formyl peptide receptor 2 (huFPR2).

197 SAnxA1 bound and activated formyl peptide receptor 2 in a similar way as the parent

198 een phosphatidylserine on the dying cell and formyl peptide receptor 2 on the phagocytosing microglia

199 regulation of ALX/FPR2 (lipoxin A4 receptor/formyl peptide receptor 2) expression.

200 ceptor-2 (FPR2/ALX) and in mFPR2(-/-) (mouse formyl peptide receptor 2) mice lacking the mouse homolo

201 s by airway epithelial cells in an ALX/FPR2 (formyl peptide receptor 2) receptor-dependent manner.

202 roteins, namely protein phosphatase 5 (PP5), formyl peptide receptor 2, and annexin 1.

203 We investigated airway levels of formyl peptide receptor 2-lipoxin receptor (FPR2/ALXR),

204 as shown by experiments with DCs lacking the formyl peptide receptor 2.

205 ayed specific binding to the AnxA1 receptor (formyl peptide receptor 2/Lipoxin A4 receptor [FPR2/ALX]

206 Formyl peptide receptor 3 (Fpr3, also known as Fpr-rs1)

207 ed gut epithelial cells resulted in specific formyl peptide receptor activation.

208 formulate requirements for these specific N-formyl peptide receptor agonists.

209 the role of the inside-out signaling through formyl peptide receptor and CXCR4 in the regulation of a

210 tin polymerization to prevent exocytosis via formyl peptide receptor and Rho kinase signaling pathway

211 iate these effects, whereas recognition by N-formyl peptide receptor family members was dispensable.

212 s a noncanonical GRK that phosphorylated the formyl peptide receptor FPR1 and facilitated neutrophil

213 ecently presented evidence for a role of the formyl peptide receptor in vivo.

214 eins were previously reported to function as formyl peptide receptor inhibitors.

215 ed ERK and p38 MAPK signaling in response to formyl peptide receptor stimulation.

216 ulation and cAMP accumulation in response to formyl peptide receptor stimulation.

217 c peptide WKYMVm, a selective agonist of the formyl peptide receptor, a 2-fold increase in leukocyte

218 luminal casts depends on the high-affinity N-formyl peptide receptor, Fpr1.

219 These include the human formyl peptide receptor, human trace amine-associated re

220 (2+)-mobilizing G protein-coupled receptors (formyl peptide receptor, P2Y2 purinergic receptor, and c

221 out experiments to study the capacity of the formyl peptide receptor-1 (FPR1) to desensitize chemokin

222 tein B1 (HMGB1), respectively, as well as to formyl peptide receptor-1 (FPR1), which interacts with A

223 polymorphonuclear neutrophils (PMNs) through formyl peptide receptor-1 and Toll-like receptor (TLR) 9

224 LL-37, via formyl peptide receptor-2 (FPR-2), triggered the release

225 ocortin-4 receptor, the Smoothened receptor, formyl peptide receptor-2 (FPR2), the relaxin receptor (

226 ll interfering RNA-induced knockdown of LXA4 formyl peptide receptor-2 (FPR2/ALX) and in mFPR2(-/-) (

227 togen-activated protein kinase pathway in an formyl peptide receptor-dependent manner, delineating a

228 drial ATP production and requires an initial formyl peptide receptor-induced Ca(2+) signal that trigg

229 nctions of cathelicidin are mediated through formyl peptide receptor-like 1 (FPRL1), we hypothesize t

230 N-formyl peptide receptor (FPR1) and N-formyl peptide receptor-like 1 (FPRL1, now known as FPR2

231 ith WRW4, an antagonist of the transmembrane formyl peptide receptor-like 1 protein attenuated LL-37'

232 RvD1, by activating its receptor formyl peptide receptor2/lipoxin A4 receptor, suppresses

233 N-formyl peptide receptors (FPRs) are critical regulators

234 N-Formyl peptide receptors (FPRs) are G protein-coupled re

235 Formyl peptide receptors (FPRs) are G-protein-coupled re

236 cquisition of neuronal specificity by immune formyl peptide receptors (Fprs).

237 te ERK pathway activity via interaction with formyl peptide receptors (FPRs).

238 sion of mRNAs for annexin A1 (AnxA1) and the formyl peptide receptors [(Fprs) 1, 2, and 3], a loss of

239 Stimulation of formyl peptide receptors increases the mitochondrial mem

240 lial cells occurs via recently characterized formyl peptide receptors located in the plasma membrane.

241 The neutrophil formyl peptide receptors, FPR1 and FPR2, play critical r

242 hat LTB(4) production dramatically amplifies formyl peptide-mediated neutrophil polarization and chem

243 Mice inoculated with the formyl peptide-producing wild-type strain showed a signi

244 Endothelial-bound cathelicidin activates formyl-peptide receptor 2 on classical monocytes, result

245 Here we tested whether the formyl-peptide receptor 2/3 (Fpr2/3)--ortholog to human

246 e, we tested whether the lipoxin A4 receptor formyl-peptide receptor 2/3 (Fpr2/3; ortholog to human F

247 Formyl-peptide receptor type 2 (FPR2), also called ALX (

248 Formyl-peptide receptor type 2 (FPR2; also called ALX be

249 rophils, but not nonclassical monocytes in a formyl-peptide receptor-dependent manner.

250 N-formyl peptides alone did not induce monocyte IL-8 relea

251 Chemokines and mitochondrial products (e.g., formyl peptides and mitDNA) collaborate in neutrophil-me

252 MTDs include formyl peptides and mitochondrial DNA.

253 whereas, the combination of mitochondrial N-formyl peptides and mitochondrial transcription factor A

254 Although several N-formyl peptides are known to bind to these receptors, mo

255 ing of formyl peptide receptor 1 (FPR1) by N-formyl peptides can activate neutrophils and may represe

256 dient of chemokines and mitochondria-derived formyl peptides collaborate to guide neutrophils to site

257 ancy of these G-protein-coupled receptors by formyl peptides has been shown to induce regulatory phos

258 Considering the importance of N-formyl peptides in inflammatory processes, our data indi

259 The capacity of mitochondrial N-formyl peptides to activate monocytes was confirmed usin

260 tor sensory neurons-detect bacterial toxins, formyl peptides, and lipopolysaccharides through distinc

261 ondrial fraction of the cell, particularly N-formyl peptides, contributes significantly to the activa

262 response to primary chemoattractants such as formyl peptides, is important in initiating the inflamma

263 quisitely regulates neutrophil chemotaxis to formyl peptides, which are produced at the core of infla

264 le in neutrophil activation and migration to formyl peptides.

265 The presence of the lipoxin A4 receptor/formyl peptidyl receptor (ALX/FPR) in KS patient tissue

266 enylnitrene was generated by photolysis of 2-formyl phenylazide isolated in Ar, Kr, and Xe matrixes a

267 Triplet 2-formyl phenylnitrene was generated by photolysis of 2-fo

268 or 2,5-dihydrofuran yields some of the beta-formyl product.

269 The identification of N-formyl-protected glycine as the ligand (Formyl-Gly-OH) w

270 tween the phosphoryl oxygen and the aldehyde formyl proton present in TADDOL-derived catalysts.

271 and the phosphoryl oxygen interacts with the formyl proton.

272 The formyl-radical equivalent then undergoes nickel-catalyze

273 report the first direct catalytic method for formyl-selective deuterium labeling of aromatic aldehyde

274 itions with PhSiH3 , an observable magnesium formyl species may be intercepted for the mild reductive

275 e kinetics and mechanism of the reactions of formyl-stabilized ylide Ph3P horizontal lineCHCHO (1) an

276 Formyl-substituted aryl and heteroaryl MIDA boronates we

277 egy toward the production of a wide range of formyl-substituted rings with alkene transposition.

278 These formyl substitution derivatives exhibit different spectr

279 t different spectral shifts according to the formyl substitution position.

280 etic intermediate, was proposed to signal 10-formyl-tetrahydrofolate (10f-THF) deficiency in bacteria

281 al one-carbon metabolism intermediate, N(10)-formyl-tetrahydrofolate (N(10)-CHO-THF).

282 xidation of methylene tetrahydrofolate to 10-formyl-tetrahydrofolate is coupled to reduction of NADP(

283 ne encodes a mitochondrial monofunctional 10-formyl-tetrahydrofolate synthetase, termed MTHFD1L.

284 metabolism revealed complete oxidation of 10-formyl-tetrahydrofolate to make NADPH.

285 b were rescued by exogenous application of 5-formyl-tetrahydrofolate, a stable folate that was readil

286 ired for the stimulation of germ cells by 10-formyl-tetrahydrofolate-Glun and dihydropteroate.

287 proliferation is stimulated by the folate 10-formyl-tetrahydrofolate-Glun both in vitro and in animal

288 based formulas contained polyglutamates of 5-formyl-tetrahydrofolate.

289 of one-carbon groups for the synthesis of 10-formyl-THF and other one-carbon intermediates; these are

290 methylene-tetrahydrofolate (CH(2)-THF) to 10-formyl-THF in adult mammalian mitochondria are currently

291 A monofunctional 10-formyl-THF synthetase (MTHFD1L gene product) functions i

292 lar [(3)H]THF cofactors derived from [(3)H]5-formyl-THF were depleted in R5 cells compared with those

293 milk tetrahydrofolate (THF), 5-methyl-THF, 5-formyl-THF, 5,10-methenyl-THF, and UMFA were measured wi

294 dria to cytoplasm, producing formate from 10-formyl-THF.

295 Herein, we report that heptamer formyl thiophene acetic acid (hFTAA) passes the blood-br

296 mbinant bacterial and archaeal FTs catalyzed formyl transfer from 5-CHO-THF to glutamate, with k(cat)

297 ion and structure determination of two new 3-formyl tyrosine metabolites.

298 After expulsion of the formyl unit, both proton-independent and -dependent path

299 on 3 or 5 in the gramicidin A (gA) sequence: formyl-VG(2)A(3)LA(5)VVVWLWLWLW-ethanolamide (d-residues

300 ioselective construction of enolizable alpha-formyl vinylic stereocenters without racemization or ole