ライフサイエンスコーパス: fornix

1 host phenotype (vaginal pH) in the posterior fornix.

2 wab was taken from the inferior conjunctival fornix.

3 lengths of remyelinated nerve fibers in the fornix.

4 was collected from the inferior conjunctival fornix.

5 oro-parietal regions as well as splenium and fornix.

6 iscs remain for at least 1 hour in the lower fornix.

7 peared to be related to abnormalities of the fornix.

8 ng of such associations also depended on the fornix.

9 selectively disrupted by transection of the fornix.

10 ese cortical inputs were less reliant on the fornix.

11 al inputs to the hippocampus via the fimbria-fornix.

12 ron, had a main axon that coursed toward the fornix.

13 ll as to the ipsilateral hippocampus via the fornix.

14 gion lateral to the descending column of the fornix.

15 lowing unilateral transection of the fimbria fornix.

16 is, or unilateral transection of the fimbria fornix.

17 tory gating following lesions of the fimbria-fornix.

18 paration containing the MS-DB and the dorsal fornix.

19 ngth of the palpebral conjunctiva toward the fornix.

20 um 3 weeks before transection of the fimbria fornix.

21 matically in the corpus callosum and fimbria/fornix.

22 from the ventral hippocampus via the fimbria/fornix.

23 expressing purulent fluid into the superior fornix.

24 normalities of the septum pellucidum and the fornix.

25 ions of limbic fiber pathways, including the fornix.

26 he mammillary bodies via the postcommissural fornix.

27 ale sex (35% vs 49%, P < .0001), location in fornix (2% vs 6%, P = .0016) and tarsus (1% vs 4%, P = .

28 We have lesioned the fimbria fornix, a major pathway of septal cholinergic fibers.

29 M. E. Bouton, who found that lesions of the fornix abolished reinstatement of aversively conditioned

30 t-lid technique, a procedural improvement if fornix access is difficult.

31 Low-frequency stimulation of the fornix activates the hippocampus and other areas of the

32 Although damage to the human fornix also results in memory impairment, it is not know

33 Finally, both the fornix and anterior thalamic lesions severely impaired T

34 utaneous junction of the eyelid, through the fornix and bulbar conjunctiva.

35 mplanted with an electrode into the proximal fornix and dorsal hippocampal commissure on the language

36 re used to analyze the relationships between fornix and hippocampal measures and their predictive pow

37 The fornix and hippocampus are critical to recollection in t

38 43 labelled fibers in terminal fields, i.e., fornix and hippocampus, that were not observed in contro

39 t sections located in the ipsilateral dorsal fornix and in the contralateral parahippocampal white ma

40 athology in a number of tracts including the fornix and increased structural connectivity between the

41 fornix microstructure and the other on both fornix and left PHC.

42 and a second limbic connection following the fornix and the anterior limb of the internal capsule.

43 ences between anatomical regions such as the fornix and the cingulum bundle or corpus callosum.

44 Furthermore, as the volumes of the left fornix and the left mammillary bodies decreased, the dif

45 st that degradation of microstructure in the fornix and the uncinate fasciculus make critical but dif

46 iation tracts such as the anterior cingulum, fornix and uncinate fasciculus.

47 ip between microstructural properties of the fornix and variation in Body Mass Index (BMI), within no

48 ociated with memory loss when accompanied by fornix and/or mammillary body atrophy.

49 laris, radiofrequency lesions of the fimbria-fornix, and aspiration lesions of the frontal cortex on

50 gions including the corpus callosum, fimbria/fornix, and cerebellar deep white matter.

51 al cortices, the corpus callosum and fimbria/fornix, and cerebellar white matter.

52 Tear wash fluid was collected from inferior fornix, and conjunctival epithelium was obtained by impr

53 at involved the body of the corpus callosum, fornix, and main anterior-posterior pathways (P < .05).

54 g the inferior temporal cortex, hippocampus, fornix, and mammillary bodies.

55 ression was detected in the corpus callosum, fornix, and posterior portion of the anterior commissure

56 sity of oligodendrocytes in corpus callosum, fornix, and spinal cord is 20-40% greater in males compa

57 r FA were found in the hippocampal cingulum, fornix, and stria terminalis, posterior corona radiata,

58 n all divisions of the corpus callosum, left fornix, and subgenual cingulum compared with control sub

59 reas: superior and inferior areas of bulbus, fornix, and tarsus of male Sprague-Dawley rats (n = 6).

60 To compare effectiveness of fornix- and limbal-based conjunctival flaps in trabecule

61 n the initial acquisition stage, control and fornix animals were equally proficient in learning the d

62 ion sub-scores to FA values in the cingulum, fornix, anterior commissure, corpus callosum and right u

63 spatial statistics suggested the crus of the fornix as a focus for this relationship.

64 nhuman primates, critically highlighting the fornix as a source of interindividual variation in scene

65 ssion of the gel-forming mucin begins at the fornix at 7 days after birth and is correlated with the

66 ent amplifying cells that migrate toward the fornix at a rate of approximately 1.7 mm/d with a transi

67 , can also prevent the loss of these fimbria fornix axotomised cholinergic neurons, where GM1 alone d

68 In the fornix-based and limbal-based surgery, mean IOP at 12 mo

69 ng controversies such as limbus-based versus fornix-based approaches to trabeculectomy and one-site v

70 oped bleb leaks significantly later than did fornix-based cases (2.1 vs. 1.0 years; P=0.002, GEE mode

71 eriod after surgery (P=0.02, Cox model), and fornix-based cases requiring cataract surgery had the op

72 Eyes undergoing the fornix-based operation had a greater risk of cataract su

73 all available follow-up was more common with fornix-based operations (P=0.01, GEE model).

74 ased operations during the first 4 years and fornix-based operations during the last 4 years.

75 leaks within 4 years after both limbus- and fornix-based operations; however, limbus-based cases dev

76 Fornix-based procedures have more symptomatic hypotony a

77 rgery, the success rates of limbus-based and fornix-based trabeculectomy were not statistically diffe

78 s rates are similar between limbus-based and fornix-based trabeculectomy.

79 owing no difference in effectiveness between fornix-based vs limbal-based trabeculectomy surgery, alt

80 asses were identified in the upper and lower fornix bilaterally and involved the tarsus of the right

81 Axial diffusivity was increased in the fornix bilaterally and right dorsal-anterior cingulum.

82 demonstrated that transection of the fimbria/fornix blocked the excitatory effect of corticotropin-re

83 Fornix body volume and axial diffusivity were highly sig

84 ed change in the cross-sectional area of the fornix, but there is a significant loss of myelinated ne

85 Deepening of the inferior fornix by removing degenerated Tenon's and reconstructio

86 iour in the white matter tracts of interest (fornix, cingulum and corpus callosum).

87 ded the splenium of the corpus callosum, the fornix, cingulum, and superior and inferior longitudinal

88 call tasks in patients with anomalies of the fornix compared with those without (P = .04, exact two-t

89 Incisional biopsy specimens of ventral fornix conjunctiva were collected before gland removal (

90 mic-prefrontal interactions, mediated by the fornix, contribute to the healthy functioning of network

91 ocated lateral to the PVN and ventral to the fornix, corresponding to the lateral hypothalamic area a

92 superior longitudinal fasciculus, bilateral fornix (cres)/stria terminalis, genu and splenium of the

93 enu, thalamus, right posterior cingulum, and fornix crus (seven studies; largest cluster, 980 voxels;

94 ferior fronto-occipital fasciculus, and left fornix crus (six studies; 323 voxels; z = 1.7; P = .001)

95 2]) and tracts involved in limbic circuitry (fornix crus [AD, beta = 0.02 (P = .046)] and cingulum [R

96 In the presence of fornix damage in mild cognitive impairment (MCI), a reco

97 s were found between the apparent effects of fornix damage in these clinical cases and those observed

98 These findings not only indicate that fornix damage is sufficient to induce anterograde amnesi

99 ammillary body volume (which atrophies after fornix damage).

100 ontinuing until p28, the ipsilateral fimbria fornix degenerates.

101 ould be among the first studies establishing fornix degeneration as a predictor of incipient cognitiv

102 Fornix degeneration is a feature of aging and Alzheimer'

103 ory for scenes presented on touch screens is fornix dependent.

104 An FICD modification of a custom-designed fornix depth measurer (FDM) was validated and used for m

105 o provide normative data for upper and lower fornix depths (FDs) and fornix intercanthal distance (FI

106 epto-hippocampal glutamatergic fibers in the fornix did not have an effect.

107 Lesions of the fimbria-fornix disrupt auditory gating by preventing cholinergic

108 The fornix does not show the abnormalities in cross-sectiona

109 For 50% of the trials, the fornix electrode was continuously stimulated using a bur

110 PSPMNs located around the fornix express orexin, whereas those located around the

111 ween MS patients and controls were found for fornix FA (0.38 vs. 0.46, means adjusted for age and for

112 Multivariate regression analysis identified fornix FA and mammillary bodies as predictor of visual r

113 n status (P = 0.032) significantly predicted fornix FA.

114 In contrast, lesions of the fornix facilitate acquisition on this task, showing that

115 imately 100 msec duration) evoked by fimbria/fornix (FF) stimulation in a majority of neurons tested.

116 ed controls along the left and right fimbria-fornix (FF), parahippocampal WM bundle (PWMB), arcuate f

117 c nuclei (ATN) or transection of the fimbria-fornix (FF).

118 ls received a complete lesion of the fimbria-fornix (FF).

119 ts demonstrate the importance of the fimbria-fornix fiber system in spatial short-term memory but sug

120 PARA) or electrolytic lesions of the fimbria-fornix (FNX) and were tested for their (a) discriminatio

121 fimbria and the CA1 efferents via the dorsal fornix for encoding and consolidation/retrieval of class

122 rnix regions-of-interest were used to derive fornix fractional anisotropy (FA).

123 g the mammillary bodies: the postcommissural fornix from the hippocampal formation and Gudden's ventr

124 They run along the fornix from the hypothalamus, along the supraoptic decus

125 status than was cross-sectional area of the fornix, global mean white-matter FA and left frontal lob

126 Transection of the nonhuman primate fornix has been shown to impair learning of configuratio

127 the later stages of decline, the ability of fornix-hippocampal markers to predict the earliest clini

128 mas disrupted adjoining neural tissue in the fornix, hippocampus, and dorsal diencephalon; in one cas

129 o the magnocellular mediodorsal thalamus and fornix impaired postoperative retention of the preoperat

130 otic membrane resulted in achieving a deeper fornix in 83% of patients with various cicatrizing conju

131 in 23 (72%), bulbar conjunctiva in 31 (97%), fornix in 9 (28%), tarsus in 3 (9%), semilunar fold in 1

132 GMS drops were retained in the inferior fornix in all animals for the length of the study.

133 store the tear meniscus, but also deepen the fornix in CCh patients.

134 ports the idea that the main function of the fornix in macaque monkeys is to support new learning abo

135 The precise involvement of the fornix in memory, however, has been difficult to ascerta

136 for a role beyond the spatial domain for the fornix in monkeys.

137 e matter bundle, and the ipsilateral fimbria-fornix in regions located within the medial temporal lob

138 ned mainly to the choroid plexus and ventral fornix in the roof of the third ventricle, occasionally

139 in the white matter, and specifically in the fornix, in humans and rats.

140 The fornix, in turn, may display alterations in microstructu

141 ssment; no studies were found that evaluated fornix incisions.

142 terned electrical stimulation of the fimbria-fornix increased TGC in amnestic animals and partially r

143 mice received weekly periocular conjunctival fornix injections of a dexamethasone-21-acetate (DEX-Ac)

144 for recall, there was a significant group x fornix interaction, indicating that the association betw

145 for upper and lower fornix depths (FDs) and fornix intercanthal distance (FICD) within a healthy Sou

146 ncle (corticospinal tract), corpus callosum, fornix, internal capsule (thalamocortical and corticotha

147 The fornix is a major pathway through which neurons project

148 y demonstrated that burst stimulation of the fornix is able to significantly improve memory in a rode

149 whether the fiber number or structure of the fornix is abnormal in schizophrenia, as was suggested by

150 mpairment in monkeys with transection of the fornix is exacerbated by prior depletion of acetylcholin

151 Decreased FA in of the columns of the fornix is particularly robust in early FAD and may provi

152 The fornix is the main tract between the medial temporal lob

153 lts suggest that one specialized role of the fornix is to process temporal information.

154 Transection of the fimbria fornix leads to retrograde degeneration of axotomised se

155 fferences were also found in the body of the fornix, left fimbria, and superior longitudinal fascicul

156 animals 2 weeks following unilateral fimbria-fornix lesion.

157 (RTA) into the lateral ventricle of fimbria-fornix lesioned animals.

158 behavioral arrest could be reconstituted in fornix-lesioned animals by inducing synchronous activity

159 of auditory gating by DMXB-A in the fimbria-fornix-lesioned rats was blocked by intracerebroventricu

160 XB-A restored auditory gating in the fimbria-fornix-lesioned rats, indicating that activation of the

161 ctions of 192 IgG-saporin (SAP-HPC), fimbria-fornix lesions (FF), or sham control surgeries were test

162 hippocampal physiology compared with fimbria-fornix lesions and septal inactivation, we observed limi

163 raining rabbits (Oryctolagus cuniculus) with fornix lesions concurrently on two discrimination tasks

164 Fornix lesions did not affect either version of the task

165 Rats with fornix lesions had normal baseline levels of hippocampal

166 During the same task, rats with fornix lesions learned to approach a visible platform bu

167 The results further imply that fornix lesions may impair memory in part by decoupling n

168 Moreover, fornix lesions need not mimic the effects of direct dama

169 Rats with fornix lesions performed well on the VPC task but were i

170 arning and memory, the results obtained with fornix lesions suggest that ACh release in the hippocamp

171 induction of Arc transcription in rats with fornix lesions that impair hippocampal learning yet leav

172 Rats with anterior thalamic lesions and fornix lesions were unimpaired on a configural learning

173 This induction is blocked by fornix lesions, which are known to disrupt activation of

174 l synaptic potentiation and Arc in rats with fornix lesions.

175 erformed a spatial task that was impaired by fornix lesions.

176 ated regions, not seen after postcommissural fornix lesions.

177 ian patient age (50 vs 61 years, P < .0001), fornix location (32% vs 54%, P < .0001), larger median b

178 eys by lesions restricted to the hippocampus-fornix-mamillary system.

179 suggests that theta burst stimulation of the fornix may be associated with improvement in visual-spat

180 Fornix MD and f measures correlated with scene, but not

181 ne among normal elderly individuals and that fornix measures would be associated with gray matter cha

182 e also observed associations between ILF and fornix microstructure and category-selective BOLD respon

183 there was no significant correlation between fornix microstructure and familiarity memory or performa

184 account for recall performance: one based on fornix microstructure and the other on both fornix and l

185 specifically associated with degradation of fornix microstructure, consistent with the view that thi

186 plore whether theta burst stimulation of the fornix might improve memory in humans.

187 In tests of AN (experiment 3), fornix monkeys performed at the same level as control an

188 WSR and BSR were intermixed (experiment 1), fornix monkeys performed below the level of the control

189 In experiment 2, fornix monkeys were significantly impaired on tests of B

190 Low-frequency stimulation of the fornix occurred in 4-hour sessions in the video-electroe

191 me fraction, f) were then extracted from the fornix of each participant, which had been reconstructed

192 Tear fluid was collected from the inferior fornix of normal subjects (n = 17) and patients with Sjo

193 before use of povidone iodine; the inferior fornix of the fellow eye was also cultured and served as

194 At the time of enrollment, the inferior fornix of the treated eye was swept with a culture swab

195 fluoride dosimeters both into the posterior fornix of the vagina and on the skin at the beam entranc

196 atal DES exposure downregulated RUNX1 in the fornix of the vagina, where DES-associated adenosis is f

197 ross-sectional electron micrographs from the fornix of young and old rhesus monkeys using a semi-auto

198 lms collected from the inferior conjunctival fornix or bulbar conjunctiva.

199 rtical acetylcholine after the lesion of the fornix or mammillary bodies did not increase the severit

200 Animals with lesions of the fornix or perirhinal-entorhinal cortex acquired at least

201 the deficit is equivalent in magnitude after fornix or perirhinal-entorhinal damage.

202 e caruncle, but rarely are nevi found in the fornix or tarsal conjunctival surface.

203 onic stimulation of the subthalamic nucleus, fornix, or hippocampus may be effective in attenuating s

204 of the mediodorsal nucleus in thalamus, the fornix, or the dorsal hippocampus.

205 area; some were on the palpebral side of the fornix; others were present on the bulbar side.

206 s obtained from different locations (cervix, fornix, outer vaginal canal) and by different methods (s

207 We also found that FA in the columns of the fornix (P = 0.008) and left orbitofrontal lobe white mat

208 ter FA (P = 0.045), FA of the columns of the fornix (P = 0.012), area of the perforant pathways bilat

209 From preoperative imaging, the fimbria-fornix, parahippocampal white matter bundle and uncinate

210 ith larger axial and mean diffusivity in the fornix (r = 0.64 and r = 0.55 respectively), relationshi

211 The tear reservoir in the fornix rapidly replenishes the meniscus under normal cir

212 raoperative adjunction of mitomycin C during fornix reconstruction with amniotic membrane resulted in

213 thesis that low-frequency stimulation of the fornix reduces interictal epileptiform discharges and se

214 overlying mucosal lymphoid follicles in the fornix region.

215 Manual fornix regions-of-interest were used to derive fornix fr

216 ial task, and existing direct evidence for a fornix role in spatial memory comes exclusively from tas

217 emporal cortex, with the later addition of a fornix section ipsilateral to the MFB lesion.

218 rmation and its connections including CA1-4, fornix, septal nuclei, hippocampal commissure, septohipp

219 hibition of wound contraction (6.8% +/- 3.2% fornix shortening) and the formation of a tissue that re

220 ds had closed by contraction (26.4% +/- 5.0% fornix shortening) and the formation of scarlike tissue

221 osed with chronic domoic acid toxicosis, the fornix showed signs of altered diffusion properties indi

222 ampal projections, which coursed through the fornix, showed a rostrocaudal gradient as more arose in

223 Fornix status was assessed directly by overall volume an

224 Fornix stimulation elicited evoked responses in the hipp

225 their projections to the hippocampus through fornix stimulations had no effect on theta rhythms, sugg

226 rential effects on the hippocampal cingulum, fornix, stria terminalis, posterior corona radiata, and

227 ecuneus, hippocampus, amygdala, caudate, and fornix/stria terminals.

228 ting that the association between recall and fornix structure was weaker in patients.

229 The terms giant fornix syndrome, senile sunken upper lids, and prostagla

230 atter (corpus callosum, corticospinal tract, fornix system) increase; in TASTPMs such trends often va

231 Higher microstructural integrity in the fornix tail was found to be associated with significantl

232 cortex, corpus callosum, habenulae, septum, fornix, thalamus, caudate putamen and a few in fasciculu

233 The men had a lower fiber density in the fornix than the women.

234 o-anterior temporal lobe, including PrC) and fornix (the main HC input/output pathway) correlated wit

235 g a 5-mul fluorescein drop into the inferior fornix, the inferior tear meniscus was depleted using a

236 nesia depends on determining the role of the fornix, the major interlinking fiber tract.

237 Transecting the fornix, the major route from hippocampus to subcortical

238 n to link components of memory networks: the fornix, the parahippocampal cingulum, and the uncinate f

239 dle passing through the medial septum is the fornix, the primary efferent pathway for the hippocampus

240 emonstrated that DBS targeted to the fimbria-fornix, the region that appears to regulate hippocampal

241 into corpus callosum, striatum, and fimbria fornix to differentiate into the NG2-positive nonmyelina

242 keys received a bilateral transection of the fornix to disconnect subcortical inputs and outputs of t

243 The hippocampus is connected via the fornix tract to the hypothalamus, orbitofrontal cortex,

244 icine-pretreated, control, untreated fimbria-fornix-transected (5 days), as well as perforant path-st

245 ased on the delayed matching-to-sample task, fornix-transected and normal control monkeys were presen

246 Fornix-transected monkeys were impaired in learning new

247 ere impaired nonsignificantly, and less than fornix-transected rats in an earlier study.

248 Both fornix transection and selective neurotoxic hippocampal

249 Taken together, these results show that fornix transection causes a long-lasting impairment in a

250 In contrast to these effects, fornix transection did not impair performance when famil

251 iscrimination learning task, they found that fornix transection did not impair recall of preoperative

252 Fornix transection impaired the learning of these associ

253 Here the authors demonstrate that fornix transection impairs learning about spatial stimul

254 eports of spatial learning impairments after fornix transection in nonhuman primates, critically high

255 acquired preoperatively was unaffected after fornix transection in the macaque, whereas new postopera

256 ive reassigned stages, however, monkeys with fornix transection made on average three times as many e

257 Fimbria-fornix transection resulted in a marked loss of SP fiber

258 This suggests that fornix transection should impair postoperative new learn

259 In experiment 4, fornix transection significantly impaired tests of WSR a

260 d subjacent parahippocampal cortex, added to fornix transection, had no effect, thus demonstrating th

261 Similar to the effects of fimbria-fornix transection, Pb exposure resulted in a long-term

262 ed by lesions of the mammillary bodies, like fornix transection, was exacerbated by prior removal of

263 Fimbria-fornix transections (FFTs), conducted 1 day after rats w

264 tion, had no effect, thus demonstrating that fornix transections eliminated the contribution of the h

265 molgous) monkeys received unilateral fimbria fornix transections followed by chronic intracranial can

266 In previous work, the authors found that fornix transections impaired the ability of macaque monk

267 describing larger GFAP RNA inductions after fornix transections in aged mouse hippocampus.

268 The 'upper fornix trap', where the contact lens may be retained by

269 ion of anterior temporal stem, amygdala, and fornix (TS+AM+FX) and were unimpaired in performing the

270 0.03% eye ointment instilled into the lower fornix twice daily for the first 2 weeks, followed by no

271 orm cortex, and a white-matter index for the fornix, uncinate fasciculus and inferior longitudinal fa

272 n isolated from the nictitating membrane and fornix using explant cultures.

273 ecline but was significantly associated with fornix volume and diffusivity (P = .004).

274 Predictive fornix volume reductions might be explained at least in

275 In this study relating fornix volume with memory, we made magnetic resonance im

276 A (0.38 vs. 0.46, means adjusted for age and fornix volume, P<.0005) and mammillary body volumes (age

277 RCTs in which benefits and complications of fornix- vs limbal-based trabeculectomy for glaucoma were

278 n demonstrated that FA of the columns of the fornix was a better predictor of mutation status than wa

279 Burst stimulation of the fornix was not perceived by any of the participants but

280 A section of fornix was removed from each hemisphere of postmortem br

281 ted decline in white matter integrity of the fornix, was associated with lower cross-sectional episod

282 Pathological changes in the dorsal fornix were beyond the margins of resection, and contral

283 In both species, changes in diffusion in the fornix were correlated with diffusion changes in the hip

284 on nerve fibers and neuroglial cells in the fornix were examined in 25 rhesus monkeys between 4 and

285 ampal cingulum bundle, stria terminalis, and fornix were investigated as regions of interest.

286 isions of the corpus callosum, cingulum, and fornix were measured as indicators of trait differences

287 and rats with radio-frequency lesions of the fornix were tested on the visual paired comparison task

288 of the anterior temporal stem, amygdala and fornix were unable to relearn a 2-choice object discrimi

289 with decreased fractional anisotropy in the fornix when compared with clinical (p < .001) or healthy

290 groups consistently had decreased FA in the fornix, which correlated with cognitive performance (rho

291 he presence of bilateral interruption of the fornix, which occurred in three of the subjects.

292 nvestigate whether individual differences in fornix white matter microstructure in neurologically hea

293 Our preliminary hypothesis was that fornix white matter volume should be a significant predi

294 Thus, microstructural changes in fornix white matter were observed in older adults with i

295 buckle was inserted deeply into the inferior fornix without suture after pneumatic retinopexy and was