ライフサイエンスコーパス: founder line

1 lines derived from eight genetically diverse founder lines.

2 although this was more variable in different founder lines.

3 orter gene and used to create six transgenic founder lines.

4 variable levels of expression in individual founder lines.

5 cDNA and utilized this transgene to generate founder lines.

6 tissues, including the thymus in some of the founder lines.

7 ric bud causes reduced branching in multiple founder lines.

8 lies; however, allelic effects differ across founder lines.

9 tween 3- and 50-fold higher depending on the founder line, and this occurred within 24-48 h after dos

10 rsensitive sites, is expressed in only a few founder lines, and expression is dysregulated in CD8(+)

11 derived from two independent TetOp-DeltaFosB founder lines but not in single NSE-tTA transgenic contr

12 Study of three founder lines by FACS showed overexpression to varying e

13 The founder line carrying eight copies of this transgene has

14 The analysis of mice from six different founder lines demonstrated that this genomic DNA fragmen

15 WAP-h-Int3sh females from each of the founder lines develop mammary tumors, but with a long la

16 Although some transgenic mice from one founder line developed amyloidosis in the intestine, no

17 One founder line developed compound MTC/PTC at low frequency

18 Some transgenic founder lines did not demonstrate reporter gene expressi

19 Two of the founder lines did not have a demonstrable phenotype (M-4

20 ary thyroid carcinoma (PTC) depending on the founder line examined.

21 Two of six transgenic founder lines exhibited brain-selective expression of th

22 All tested founder lines exhibited red blood cell-specific expressi

23 All three founder lines exhibited strong suppression of IgE in res

24 The founder line exhibiting the highest level of suppression

25 Twelve of twlve NPHS2 mouse founder lines expressed beta-gal exclusively in podocyte

26 Three founder lines expressed this transgene and constitutivel

27 2 generations of free recombination among 60 founder lines, following modification of the mating syst

28 DNA integrations in our genomic engineering founder lines for the purpose of generating complex knoc

29 ere human CD8 beta+ varied, depending on the founder line, from 4 to 88%, whereas the percentage amon

30 In each of six founder lines, high-level luciferase activity was eviden

31 ckcrossed homozygous transgenic animals from founder line I had plasma PAI-1 levels of 23+/-12 ng/mL.

32 erminal repeat (MMTV-LTR) promoter, and four founder lines identified.

33 (5) Including observations on the founder lines in the QTL analysis should be avoided as i

34 in thymic lymphomas from multiple transgenic founder lines, including one line in which 15 of 15 prim

35 is produced in nonlymphoid tissues from all founder lines, including tissues that do not express end

36 Mammary gland development in all founder lines is normal and the females can lactate.

37 Formation of epiblast (EPI) - the founder line of all embryonic lineages - and extra-embry

38 6 -> Ser) was used to generate 15 transgenic founder lines of hA-IImon mice, that contained plasma hA

39 tively transferred into different transgenic founder lines of mice expressing HA as a peripheral self

40 We generated multiple founder lines of mice with cardiac-restricted overexpres

41 ge number of contrasting RSA traits among 25 founder lines of the maize nested association mapping po

42 and B cells from three independently derived founder lines of transgenic mice bearing a recombined he

43 hematopoietic disease, we developed separate founder lines of transgenic mice, with the tetracycline

44 Founder line TgA, with the lowest level of IL-7 overexpr

45 In contrast, in the highest overexpressing founder line, TgB, alphabeta T-cell development was dist

46 A transactivator founder line that strongly expressed PF4-driven tTA-vira

47 We generated two independent transgenic mice founder lines that express a stable variant of active hu

48 In two independent founder lines, this -306 to +3 promoter region was suffi

49 Breeding two founder lines together produced mice with an activity of

50 evealed that one 570 kb YAC, in two separate founder lines, was associated with distinct learning def

51 Two transgenic founder lines were generated and independently bred to s