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1 rostructural integrity (mean diffusivity and fractional anisotropy).
2 gray matter volume, hippocampal volume, and fractional anisotropy.
3 hizo-Bipolar Scale, showed correlations with fractional anisotropy.
4 rebrospinal fluid were associated with lower fractional anisotropy.
5 ec vs [0.9 +/- 0.09] x 10(-3) mm(2)/sec), or fractional anisotropy (0.43 +/- 0.05 vs 0.42 +/- 0.06).
6 95% confidence interval, -25.1 to -2.2) and fractional anisotropy (-0.0073; 95% confidence interval,
7 ers connecting these 2 regions in patient 1 (fractional anisotropy, 0.294; P = .047) but not in patie
9 Using diffusion tensor imaging, we defined fractional anisotropy, a metric related to white matter
11 genual structures, with frontal white matter fractional anisotropy abnormalities partially encircling
12 either significant increases or decreases in fractional anisotropy across a comparable 12-week interv
13 mptoms was positively associated with higher fractional anisotropy across all affected youth (F3,85 =
14 ion, female patients had significantly lower fractional anisotropy across all tracts compared with fe
15 een-sibling correlations were found for mean fractional anisotropy across the tract-based spatial sta
17 ruption in interhemispheric circuitry (i.e., fractional anisotropy alterations in the corpus callosum
20 entify: (i) the relationships between median fractional anisotropy and apathy, depression and cogniti
21 onvolution-based tractography indicated that fractional anisotropy and apparent fiber density in trac
23 tiple regression analyses revealed decreased fractional anisotropy and decreased axial diffusivity wi
27 group demonstrated lower CC integrity (lower fractional anisotropy and higher mean diffusivity) and p
28 3 months post-optic neuritis predicted lower fractional anisotropy and higher radial diffusivity at 1
32 espread age-related decrease of white matter fractional anisotropy and increases of axial, radial, an
33 ne (Val) and Val/Val genotypes showed higher fractional anisotropy and lower radial diffusivity durin
34 ish immersion program correlated with higher fractional anisotropy and lower radial diffusivity in th
35 ed measures of white matter microstructure - fractional anisotropy and mean diffusivity - were quanti
36 also observed limited change in white matter fractional anisotropy and mean diffusivity in 13 players
41 ied using tractography to derive measures of fractional anisotropy and mean, axial, and radial diffus
43 f diffusion tensor metrics showed widespread fractional anisotropy and radial diffusivity differences
44 ain effects of time by group interaction for fractional anisotropy and radial diffusivity of the left
46 pattern of ischemic brain injury (increased fractional anisotropy and reduced radial diffusivity).
47 t with diffusion tensor imaging by measuring fractional anisotropy and the apparent diffusion coeffic
49 ed abnormal age-related changes with greater fractional anisotropy and volume than normal at younger
50 wed the most significant correlation between fractional anisotropy and white matter longitudinal atro
52 age-independent negative association between fractional anisotropy and years since most severe blast
53 , we examined the microstructure (indexed by fractional anisotropy) and volume of axon pathways using
55 rns and then analyzed to extract the volume, fractional anisotropy, and axial diffusivity values of t
56 aller gray matter volume, lower white matter fractional anisotropy, and higher white matter mean and
57 overlapping significant annual decreases in fractional anisotropy, and increases in axial diffusivit
59 decrease in mean diffusivity, an increase in fractional anisotropy, and the appearance of new myofibe
60 based spatial statistics were used to assess fractional anisotropy as a marker of white matter integr
63 e influence of age on gray matter volume and fractional anisotropy at a whole-brain and voxel level.
64 sess white matter integrity, with indices of fractional anisotropy, axial diffusivity, and radial dif
65 characterize the pattern of annual change in fractional anisotropy, axial diffusivity, radial diffusi
66 ers of brain microstructural integrity (i.e. fractional anisotropy, axial, mean and radial diffusivit
71 rrying the T (risk) allele showing decreased fractional anisotropy compared with other subgroups, ind
72 emotional DDs would show significantly lower fractional anisotropy compared with youth with behaviora
75 ller effects in relatives, with a continuous fractional anisotropy decrease from healthy subjects to
76 er, in participants with multiple sclerosis, fractional anisotropy decreased and mean diffusivity of
77 tices, the amygdala, and the hippocampus and fractional anisotropy decreases in white matter tracts c
78 10-14) as well as a significant whole-brain fractional anisotropy deficit (Cohen d = 0.63; P = 2.20
79 ith the severity of schizophrenia-associated fractional anisotropy deficits in the corresponding whit
80 zophrenia only after age 35, and the rate of fractional anisotropy deterioration with age was constan
86 lobal white matter integrity, as measured by fractional anisotropy (FA) (beta = -0.182, p = 0.005).
90 r, mI/Cr), as well as DTI with evaluation of fractional anisotropy (FA) and apparent diffusion coeffi
93 e bvFTD group as a whole, rates of change in fractional anisotropy (FA) and mean diffusivity (MD) wit
94 MRI measures of white-matter microstructure [fractional anisotropy (FA) and mean diffusivity (MD)] an
96 sensorimotor cortex using both diffusion MRI fractional anisotropy (FA) and quantitative immunohistoc
97 udies consistently reported abnormalities in fractional anisotropy (FA) and radial diffusivity (RD),
100 brain white matter microstructure indexed by fractional anisotropy (FA) and three broad cognitive dom
101 We used diffusion tensor imaging derived fractional anisotropy (FA) as a biomarker of aging-relat
102 imes through age 4 months; diffusivities and fractional anisotropy (FA) assessed in 7 white matter tr
104 ted up to 2014 to identify studies comparing fractional anisotropy (FA) between patients and control
105 ale participants were evaluated for seasonal fractional anisotropy (FA) changes in specific WM tracts
106 perform voxel-wise statistical comparison of fractional anisotropy (FA) data and computational morpho
107 p<0.001), where controls showed significant fractional anisotropy (FA) decrease with ageing and alco
108 Over the 2.0-year follow-up interval, global fractional anisotropy (FA) decreased by 0.0042 (P < .001
111 White matter integrity was measured with fractional anisotropy (FA) from diffusion tensor magneti
112 n groups), we replicate the finding of lower fractional anisotropy (FA) in multiple white matter trac
113 es to VF (n = 45) by voxel-based analysis of fractional anisotropy (FA) in newborn diffusion tensor i
115 und increased cortical volumes and decreased fractional anisotropy (FA) in SAD compared with healthy
117 Compared with the HC, MDD exhibited a lower fractional anisotropy (FA) in ten brain regions: the cer
118 using transcranial magnetic stimulation, and fractional anisotropy (FA) in the posterior limbs of the
119 ia and frontoparietal network with decreased fractional anisotropy (FA) in the right hemisphere and a
120 e older subjects show significant changes in fractional anisotropy (FA) in the white matter beneath t
122 the temporal lobes and corpus callosum, and fractional anisotropy (FA) index measurement of the corp
123 ual patients, were applied to each patient's fractional anisotropy (FA) maps and tested for its abili
132 ing MTR reduction, a concurrent reduction in fractional anisotropy (FA) occurs proximal to the lingua
134 uctural organization as indicated by reduced fractional anisotropy (FA) primarily in interhemispheric
136 conduct genome-wide association analysis of fractional anisotropy (FA) value measured using diffusin
142 significant difference in cervical cord mean fractional anisotropy (FA) was found between healthy sub
143 e values lower than controls (p < 0.05), and fractional anisotropy (FA) was lower within the left unc
144 Quantitative analysis of ulnar nerve T2 and fractional anisotropy (FA) was performed, and T2 and FA
146 ne whether differences in white matter tract fractional anisotropy (FA) were associated with neurocog
148 and lambda3), the mean diffusivity, and the fractional anisotropy (FA) were derived from the DTI dat
152 ith microstructural disorganization (reduced fractional anisotropy (FA)) and axonal dysfunction (redu
154 sion tensor imaging was performed to measure fractional anisotropy (FA), a putative measure of myelin
155 re compared with repeated-measures ANOVA for fractional anisotropy (FA), and magnetization transfer r
156 bda3), apparent diffusion coefficient (ADC), fractional anisotropy (FA), and maximal anisotropy (lamb
157 atistics were used to investigate changes in fractional anisotropy (FA), axial diffusivity (AD) and r
158 ing diffusion tensor imaging (DTI) measures: fractional anisotropy (FA), axial diffusivity (AD), and
159 I with apparent diffusion coefficient (ADC), fractional anisotropy (FA), fiber number (FN) and cerebr
160 n white-matter (WM) microstructure, as lower fractional anisotropy (FA), have been reported in adoles
161 ffusivity (AD) without significant change in fractional anisotropy (FA), mean diffusivity (MD) or rad
162 data were acquired and analyzed in terms of fractional anisotropy (FA), mean diffusivity (MD), radia
164 tatistics analytic pipeline to first analyze fractional anisotropy (FA), the most commonly employed m
168 istics studies were identified that compared fractional anisotropy (FA; a marker for WM integrity) in
169 d through diffusion tensor imaging (DTI) and fractional anisotropy (FA; an index of white matter inte
170 Results revealed significantly decreased fractional anisotropy (FA; P=.021) and a trend towards s
171 Four estimates of white matter integrity (fractional anisotropy [FA] and mean [MD], radial [RD], a
172 Voxelwise linear regression (heading vs fractional anisotropy [FA]) was applied to identify sign
174 morphometry) and microstructural integrity (fractional anisotropy, FA) in first-episode treatment-na
175 atter tracts, and microstructural integrity (fractional anisotropy, FA) was assessed using tract-base
176 erformed cortical thickness and white matter fractional anisotropy for the prediction of chronologica
177 lume and thickness, and mean diffusivity and fractional anisotropy from co-registered diffusion maps
178 cerebral white matter damage as evaluated by fractional anisotropy from diffusion tensor MRI schedule
181 subgroup of chronic patients showed reduced fractional anisotropy in a portion the splenium, the for
182 ity of return to the origin, and generalized fractional anisotropy in a sample of 40 euthymic patient
184 1 risk variants predicted lower white matter fractional anisotropy in an age-independent manner in fr
185 arger visual cortex effects also had reduced fractional anisotropy in an anterior portion of the left
186 he tract segment [P </= .0001] and increased fractional anisotropy in approximately 16% of the tract
187 After 12 weeks, there was an increase in fractional anisotropy in both responders and non-respond
188 s treated with chemotherapy alone had higher fractional anisotropy in fibre tracts within the left (P
191 ed that SPD would be associated with reduced fractional anisotropy in regions implicated in top-down
192 er was associated with significantly reduced fractional anisotropy in regions that included frontal l
193 arpal tunnel syndrome demonstrated increased fractional anisotropy in several regions and, for these
194 and nonimpaired groups in the association of fractional anisotropy in the forceps major with number o
198 ity, was associated with significantly lower fractional anisotropy in the left uncinate (standardized
200 ulcal regions with a significant decrease in fractional anisotropy in the patient group compared to c
201 rtate ratio in the thalamus and in preserved fractional anisotropy in the posterior limb of the inter
202 erally in the uncinate fasciculus (increased fractional anisotropy in the right [P = .001] and axial
203 all subacute neglect patients had decreased fractional anisotropy in the second (II) and third (III)
204 ients with mTBI and depression had decreased fractional anisotropy in the superior longitudinal fasci
206 h structural connectivity as measured by the fractional anisotropy in the white matter underlying the
207 l measures of affective symptom severity and fractional anisotropy in these tracts across all partici
208 body/isthmus of the corpus callosum and that fractional anisotropy in this region was related to age
209 cts with SPD exhibited significantly reduced fractional anisotropy in tracts distributed bilaterally,
210 sue volumes and white matter microstructure (fractional anisotropy) in 134 PLWH receiving suppressive
211 res reflecting neuroanatomical connectivity (fractional anisotropy) in 77 children [40 controls (20 f
213 tial statistics showed a marked reduction of fractional anisotropy, increase of radial diffusivity (P
216 icant regional gray matter volume decreases, fractional anisotropy increases, and mean diffusivity de
217 ition into independent components and in the fractional anisotropy index of white matter integrity us
218 ian maps from deformation-based morphometry; fractional anisotropy maps from diffusion tensor images)
221 ric mean ratio 1.09, 95% CI 0.90 to 1.32) or fractional anisotropy (mean difference -0.01, 95% CI -0.
222 95% CI: 0.051, 0.129; P < .001), with lower fractional anisotropy (mean difference in z score per st
225 us, and cerebellum), three of the contrasts (fractional anisotropy, mean diffusivity, and generalized
227 , and diffusion tensor imaging metrics, i.e. fractional anisotropy, mean, axial and radial diffusivit
229 sk performance significantly correlated with fractional anisotropy measures in the middle frontal gyr
231 rve latency was associated with reduction of fractional anisotropy near (i) contralesional hand area
232 and right ATR anterior thalamic radiation FA fractional anisotropy (odds ratio, 0.74; 95% CI confiden
235 he model for cortical thickness consisted of fractional anisotropy of NAWM, NLV, and patient age and
236 (P = 8.8 x 10(-7)) negative association with fractional anisotropy of the forceps major (effect size
239 fusion tensor imaging analysis revealed that fractional anisotropy of the right cingulum was inversel
240 culus to h2 = 0.46 (SE, 0.15; P = .0009) for fractional anisotropy of the right inferior fronto-occip
242 d N-acetylaspartate (NAA)/choline (Cho), and fractional anisotropy of white-matter pathways was asses
243 ey also had lower fractional anisotropy ( FA fractional anisotropy ) of forceps major ( MNI Montreal
244 than previously used diffusion MRI metrics (fractional anisotropy or fiber-tracking recovered stream
246 rsion (P < 0.001 by paired t-test) and lower fractional anisotropy (P < 0.001 by related-samples Wilc
247 an 16% reduction of spinal cord white matter fractional anisotropy (P </= 0.0003) with a concomitant
248 d birth weight, we found significantly lower fractional anisotropy (p = .009) and axial diffusivity (
249 the frontostriatal tract at follow-up: lower fractional anisotropy (p=0.069), higher axial diffusivit
250 gions in proximity to the putamen (increased fractional anisotropy, P = .01, false discovery rate cor
251 ints frequencies were associated with higher fractional anisotropy [peak r=0.443, P<0.03] and lower r
253 -weighted imaging (to derive optic radiation fractional anisotropy, radial diffusivity, and axial dif
254 patients show no significant differences in fractional anisotropy, radial diffusivity, mean diffusiv
255 ted faster brain development in white matter fractional anisotropy (rate of increase, 2.2%; 95% CI, 0
258 ficant (p<0.05; family-wise error corrected) fractional anisotropy reductions within the parietal and
259 who stutter exhibited significantly reduced fractional anisotropy relative to controls in white matt
260 nisotropy, mean diffusivity, and generalized fractional anisotropy) revealed abnormalities in subcort
261 s, the more anxious twin exhibited decreased fractional anisotropy (t = -2.22, p = 0.032) and axial d
262 At baseline, non-responders showed lower fractional anisotropy than both responders and healthy c
263 sting into adulthood had significantly lower fractional anisotropy than the never-affected controls i
264 free-water and altered free-water corrected fractional anisotropy that included the basal ganglia, t
265 nterneurons, may account for the increase in fractional anisotropy that is seen in the thalamus and c
268 howed a significant association pathway from fractional anisotropy to processing speed to working mem
269 etween head impact exposure and change of FA fractional anisotropy value of whole, core, and terminal
270 chotic features had a lower mean generalized fractional anisotropy value than those without along the
271 he age-, sex-, and site-adjusted mean global fractional anisotropy value was 3.8% higher (95% CI, 1.1
273 d significant reductions in mean generalized fractional anisotropy values along the body and the sple
274 Spatial Statistics analysis revealed higher fractional anisotropy values for bilinguals vs. monoling
275 The severity of neglect correlated with fractional anisotropy values in superior longitudinal fa
276 ills were defined as clusters of voxels with fractional anisotropy values more than 2 standard deviat
277 f transcallosal connections as determined by fractional anisotropy values obtained from diffusion ten
278 l precentral gyri positively correlated with fractional anisotropy values of the CC subregion III, wh
280 Compared with controls, free-water-corrected fractional anisotropy values were increased for multiple
281 y structural changes as reflected by reduced fractional anisotropy values, as derived from diffusion
282 f white matter pathways, as indexed by lower fractional anisotropy values, uniquely within the pons.
290 tatistics and region of interest analyses of fractional anisotropy were conducted to examine white ma
293 -group differences in gray matter volume and fractional anisotropy were regionally localized across t
295 rates of reduction of gray matter volume and fractional anisotropy were significantly faster in males
296 -brain and regional diffusion tensor imaging fractional anisotropy were used to measure white matter
298 ostructure were also seen, including reduced fractional anisotropy with increased mean and radial dif
300 Moreover, age-associated differences in fractional anisotropy within these tracts were comparabl
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