ライフサイエンスコーパス: fractional flow reserve

1 osis) who underwent invasive angiography and fractional flow reserve.

2 Lesion severity was assessed using fractional flow reserve.

3 mental value of hybrid imaging compared with fractional flow reserve.

4 ements of relative coronary flow reserve and fractional flow reserve.

5 ovides an estimate of local hemodynamics and fractional flow reserve.

6 t of PCI assessed by the measure of post PCI fractional flow reserve.

7 (Vasodilator Free Measure of Fractional Flow Reserve [ADVISE]; NCT01118481).

8 Fractional flow reserve, an invasive index of stenosis s

9 baseline and hyperemic conditions as well as fractional flow reserve and coronary flow velocity reser

10 0.77; 95% CI, 0.71-0.83) was as accurate as fractional flow reserve and coronary flow velocity reser

11 and IMR(true) became greater with decreasing fractional flow reserve and increasing coronary wedge pr

12 FIRST (Fractional Flow Reserve and Intravascular Ultrasound Rel

13 (Fractional Flow Reserve and Intravascular Ultrasound Rel

14 of all diagnostic tests, including invasive fractional flow reserve and noninvasive coronary flow re

15 r PCI in stenoses defined physiologically by fractional flow reserve and other parameters.

16 The index of microvascular resistance (IMR), fractional flow reserve, and coronary flow reserve were

17 llowed by coronary intravascular ultrasound, fractional flow reserve, and index of microcirculatory r

18 sting and hyperemic systolic gradient [HSG], fractional flow reserve, and mean gradient) were measure

19 cations of PCI in the setting of an abnormal fractional flow reserve are unknown.

20 PI/LGE integration were determined having XA+fractional flow reserve as standard for coronary artery

21 rve) study and the DeFACTO (Determination of Fractional Flow Reserve by Anatomic Computed Tomographic

22 Contrast fractional flow reserve (cFFR) is a method for assessing

23 Pre-PCI fractional flow reserve correlated modestly with IMR(app

24 Secondary study end points were fractional flow reserve during vessel patency, the quant

25 Fractional flow reserve estimated using computed tomogra

26 -ray invasive coronary angiography (XA) with fractional flow reserve evaluation.

27 -infarct-related coronary arteries guided by fractional flow reserve (FFR) (295 patients) or to under

28 ndothelial function testing; measurements of fractional flow reserve (FFR) and coronary flow reserve

29 Discordance between fractional flow reserve (FFR) and coronary flow velocity

30 cular ultrasound (IVUS) that correlates with fractional flow reserve (FFR) and to assess the correlat

31 esonance (CMR) against invasively determined fractional flow reserve (FFR) and to establish the corre

32 CMR to detect functionally relevant CAD with fractional flow reserve (FFR) as a reference standard in

33 ctionally significant coronary lesions using fractional flow reserve (FFR) as the reference standard.

34 ronary angiography (ICA) with measurement of fractional flow reserve (FFR) by means of a pressure wir

35 percutaneous coronary intervention guided by fractional flow reserve (FFR) compared with percutaneous

36 esent study sought to determine the value of fractional flow reserve (FFR) compared with stress perfu

37 Measurement of fractional flow reserve (FFR) constitutes the current go

38 nary flow reserve (CFR) and pressure derived fractional flow reserve (FFR) for coronary stenosis asse

39 Detection of coronary ischemic lesions by fractional flow reserve (FFR) has been established as th

40 Determination of fractional flow reserve (FFR) has been proposed as a mea

41 Although pressure-only fractional flow reserve (FFR) improves outcomes compared

42 The use of fractional flow reserve (FFR) in acute coronary syndrome

43 Penetration of fractional flow reserve (FFR) in clinical practice varie

44 everity of a coronary stenosis comparable to fractional flow reserve (FFR) in diagnostic categorizati

45 ssure (Pd) to mean aortic pressure (Pa), and fractional flow reserve (FFR) in patients undergoing pri

46 d to examine the correlation between PTC and fractional flow reserve (FFR) in patients with coronary

47 the main vessel (MV) stent expansion and SB fractional flow reserve (FFR) in patients with coronary

48 s of angiographic diameter stenosis (DS) and fractional flow reserve (FFR) in predicting natural hist

49 The index has been tested against fractional flow reserve (FFR) in small trials, and the t

50 ce of these ischemic heart disease levels in fractional flow reserve (FFR) interrogated vessels remai

51 In contrast, fractional flow reserve (FFR) is a physiologic measure o

52 assessment of coronary artery disease using fractional flow reserve (FFR) is a well-validated techni

53 Fractional flow reserve (FFR) is an invasive procedure u

54 onary intervention in nonischemic lesions by fractional flow reserve (FFR) is associated with excelle

55 Fractional flow reserve (FFR) is considered by many inve

56 Fractional flow reserve (FFR) is considered nowadays as

57 However, validation of BOLD CMR against fractional flow reserve (FFR) is lacking.

58 Fractional flow reserve (FFR) is not firmly established

59 Invasive fractional flow reserve (FFR) is now the gold standard f

60 ographic assessment of coronary stenoses and fractional flow reserve (FFR) is weak.

61 Fractional flow reserve (FFR) is well established for pa

62 US), coronary flow velocity reserve (CVR) or fractional flow reserve (FFR) may further enhance the ab

63 The predictive value of fractional flow reserve (FFR) measured immediately after

64 Several studies have shown that fractional flow reserve (FFR) measurement can aid in the

65 Fractional flow reserve (FFR) measurement of intermediat

66 , and a pressure wire was used for reference fractional flow reserve (FFR) measurement.

67 nts with intermediate stenoses (53+/-7%), 14 fractional flow reserve (FFR) measurements (using 0.014-

68 ues of IVUS parameters at which to predict a fractional flow reserve (FFR) of 0.75 are unknown.

69 We hypothesized that fractional flow reserve (FFR) of an infarct-related arte

70 arge collateral contribution might alter the fractional flow reserve (FFR) of an interrogated vessel,

71 Aortic valve stenosis may influence fractional flow reserve (FFR) of concomitant coronary ar

72 There is no large report of the impact of fractional flow reserve (FFR) on the reclassification of

73 he severity of the stenosis as determined by fractional flow reserve (FFR) remains unknown.

74 Assessment of stenosis severity with fractional flow reserve (FFR) requires that coronary res

75 Fractional flow reserve (FFR) specifically relates to th

76 The utility of measuring fractional flow reserve (FFR) to assess cardiac transpla

77 Measurement of fractional flow reserve (FFR) to guide coronary revascul

78 The fractional flow reserve (FFR) value of 0.75 has been val

79 agnostic performance with respect to iFR and fractional flow reserve (FFR) were calculated for all in

80 This study sought to compare fractional flow reserve (FFR) with the instantaneous wav

81 rvention (PCI) performed on the basis of the fractional flow reserve (FFR) would be superior to medic

82 stenoses: (1) pressure wire-derived coronary fractional flow reserve (FFR), (2) Doppler wire-derived

83 Fractional flow reserve (FFR), an index of the hemodynam

84 the instantaneous wave-free ratio (iFR) and fractional flow reserve (FFR), from early experimental s

85 erived CFR and IMR were measured, along with fractional flow reserve (FFR), in 15 coronary arteries (

86 ted against the invasive reference standard, fractional flow reserve (FFR), in patients with suspecte

87 This has not previously been assessed for fractional flow reserve (FFR), instantaneous wave-free r

88 nt stenoses, as determined by measurement of fractional flow reserve (FFR), percutaneous coronary int

89 ques have been used to noninvasively compute fractional flow reserve (FFR), which is the ratio of max

90 study was to assess the clinical outcome of fractional flow reserve (FFR)-guided PCI in the treatmen

91 Fractional flow reserve (FFR)-guided PCI is associated w

92 phy for Multivessel Evaluation (FAME) study, fractional flow reserve (FFR)-guided percutaneous corona

93 s study was aimed at investigating whether a fractional flow reserve (FFR)-guided SYNTAX score (SS),

94 ng functional stenosis severity evaluated by fractional flow reserve (FFR).

95 e to intravenous adenosine on calculation of fractional flow reserve (FFR).

96 s wave-free ratio (iFR) approximation to the fractional flow reserve (FFR).

97 ly severe coronary stenoses as determined by fractional flow reserve (FFR).

98 on imaging allows to noninvasively calculate fractional flow reserve (FFR).

99 group of 26 vessels) invasive measurement of fractional flow reserve (FFR).

100 CT-IP]) assessment in predicting significant fractional flow reserve (FFR).

101 gnostic accuracy to Pd/Pa when compared with fractional flow reserve (FFR).We hypothesized that in co

102 Computed tomography-derived fractional flow reserve (FFR-CT) is a novel, noninvasive

103 n and at least 1 other severely obstructive (fractional flow reserve [FFR] </=0.8) nontarget lesion (

104 ssure with hyperemia-induced vasodilatation (fractional flow reserve [FFR] </=0.80).

105 (FAME II - Fractional Flow Reserve [FFR] Guided Percutaneous Corona

106 ing is a noninvasive alternative to invasive fractional flow reserve for evaluating hemodynamically s

107 ared with invasive coronary angiography with fractional flow reserve for the diagnosis of hemodynamic

108 vailable technologies and techniques include fractional flow reserve; grayscale intravascular ultraso

109 ned unnecessary coronary angiography (normal fractional flow reserve >0.8 or quantitative coronary an

110 0 gained Delta28.5+/-3.8 cm/s, whereas those fractional flow reserve >0.80 had a significantly smalle

111 nsidered obstructive; a stenosis <30% and/or fractional flow reserve >0.80 was nonobstructive.

112 noninfarct-related stenosis on the effect of fractional flow reserve-guided complete revascularizatio

113 The benefit from fractional flow reserve-guided complete revascularizatio

114 In patients with 3-vessel disease, fractional flow reserve-guided complete revascularizatio

115 -elevation myocardial infarction patients to fractional flow reserve-guided complete revascularizatio

116 PCI of lesions with reduced fractional flow reserve improves long-term outcome and i

117 PCI of coronary lesions with reduced fractional flow reserve improves outcomes and appears ec

118 The use of fractional flow reserve in patients with non-ST-segment-

119 The clinical use of fractional flow reserve in the culprit vessel may be pre

120 of revascularization (for example, guided by fractional flow reserve) in those patients with persiste

121 RCA fractional flow reserve increased significantly (P=0.002

122 Intravascular ultrasound (IVUS) and fractional flow reserve index (FFR) provide anatomic and

123 Pressure wire-based fractional flow reserve is considered the standard of re

124 Fractional flow reserve less than 0.8, as measured durin

125 nary flow reserve < 2.0 and pressure-derived fractional flow reserve < 0.75, both variables related s

126 artery disease (>/=90% stenosis/occlusion or fractional flow reserve </= 0.80 in vessels>2 mm).

127 Fractional flow reserve </= 0.80 was considered diagnost

128 A >/=50% stenosis at ICA or a fractional flow reserve </= 0.80 was considered signific

129 ts with significant coronary artery disease (fractional flow reserve </=0.75) to high-intensity exerc

130 failure included IMR >40 (HR, 2.2; P=0.026), fractional flow reserve </=0.8 (HR, 3.24; P=0.008), and

131 coronary vessel, or 30% to 70% stenosis with fractional flow reserve </=0.8.

132 iological cut points; treating stenoses with fractional flow reserve </=0.80 gained Delta28.5+/-3.8 c

133 Invasive fractional flow reserve </=0.80 or diameter stenosis >/=

134 A stenosis >90% and/or fractional flow reserve </=0.80 was considered obstructi

135 angina and at least 1 coronary lesion with a fractional flow reserve </=0.80 who were randomized to p

136 [9] years), 92 (44.2%) had significant CAD (fractional flow reserve </=0.80).

137 A fractional flow reserve <0.96, measured after stent depl

138 ar ultrasound, optical coherence tomography, fractional flow reserve measurements, bare-metal stents,

139 ive coronary angiography in conjunction with fractional flow reserve measurements.

140 In 8 stenosed animals with a mean fractional flow reserve of 0.64+/-0.02, hyperoxia result

141 s had mean area stenosis of 84.4% (SD 10.2), fractional flow reserve of 0.69 (0.16), and instantaneou

142 at least 1 coronary artery as indicated by a fractional flow reserve of 0.80 or less and relative dia

143 Fractional flow reserve of the IRA accurately identifies

144 onary flow reserve, and the pressure-derived fractional flow reserve of the myocardium.

145 utcome in patients from FAME 1 and 2 trials (Fractional Flow Reserve or Angiography for Multivessel E

146 puted tomography or computed tomographic and fractional flow reserve or FFR.

147 d non-invasive techniques are available (eg, fractional flow reserve or intravascular ultrasound) or

148 ow velocity reserve and the more widely used fractional flow reserve relies critically on the establi

149 eement: -0.09 to 0.03), proportional to mean fractional flow reserve (Spearman rho =0.40; P=0.036).

150 ia-Causing Stenoses Obtained Via Noninvasive Fractional Flow Reserve) study and the DeFACTO (Determin

151 sk level as assessed by noninvasive testing, fractional flow reserve testing, and coronary anatomy.

152 PCI is associated with higher postprocedure fractional flow reserve than PCI guided by angiography a

153 higher for PCI in the setting of an abnormal fractional flow reserve than with medical therapy ($9927

154 ied patients) may require a pressure-derived fractional flow reserve to differentiate persistent obst

155 graphic angiography (CTA) plus estimation of fractional flow reserve using CTA (FFRCT) safely and eff

156 CT-guided group, with a significantly higher fractional flow reserve value (0.94+/-0.04 versus 0.92+/

157 FAME 2 trial (Fractional Flow Reserve Versus Angiography for Multivess

158 lected in 497 patients enrolled in the FAME (Fractional Flow Reserve versus Angiography for Multivess

159 The Fractional Flow Reserve Versus Angiography for Multivess

160 In the Fractional Flow Reserve Versus Angiography for Multivess

161 The Fractional Flow Reserve Versus Angiography for Multivess

162 The British Heart Foundation Fractional Flow Reserve Versus Angiography in Guiding Ma

163 uded the 607 patients from the FAME 2 trial (Fractional Flow Reserve Versus Angiography in Multivesse

164 Mean fractional flow reserve was 0.68+/-0.02.

165 Mean fractional flow reserve was 0.86+/-0.06 for wire-only as

166 with examination of all coronary arteries by fractional flow reserve was performed from January 23, 2

167 ivessel coronary artery disease with reduced fractional flow reserve were randomly assigned to PCI pl

168 ltivessel Evaluation) compared PCI guided by fractional flow reserve with best MT in patients with st