ライフサイエンスコーパス: fracture

1 ceral disease or bone lesions with impending fracture).

2 ocalized throughout the healing callus after fracture.

3 ified for a well near a dynamic-conductivity fracture.

4 ess measures the resistance of a material to fracture.

5 ficantly increased risk for both MOF and hip fracture.

6 or suspicion of a nondisplaced traumatic hip fracture.

7 I, 0.45-0.99, P = .05) for patients with hip fracture.

8 oral neck, or lumbar spine; and a history of fracture.

9 nical decisions for patients at high risk of fracture.

10 CLP), have an increased risk of osteoporotic fracture.

11 levated and bmp4 was decreased at 24 h after fracture.

12 es designed to control crack propagation and fracture.

13 nsuming and usually results in postoperative fractures.

14 tion use during the prior year, and incident fractures.

15 illness have an increased prevalence of bone fractures.

16 SHR) of 1.38 [95% CI 1.06 to 1.80] for major fractures.

17 inicians, even in older patients with recent fractures.

18 atal maternal vitamin D status and childhood fractures.

19 cancer (last 12 months) were associated with fractures.

20 ith CC fractures than in patients without CC fractures.

21 her ARVs, was an independent risk factor for fractures.

22 ondary outcomes were respiratory illness and fractures.

23 ealing or weight bearing for lower extremity fractures.

24 y in addition to BMD might influence risk of fractures.

25 nd often occur with multiple consecutive rib fractures.

26 to prevent a substantial number of fragility fractures.

27 ital records were used to ascertain parental fractures.

28 e year (QALY) gained and number of fragility fractures.

29 ible, and could be effective in reducing hip fractures.

30 DF (1.25; 1.05-1.49) had higher incidence of fractures.

31 tive curves of a well surrounded by multiple fractures.

32 orotic fractures: 0.90 (0.83, 0.96); for hip fractures: 0.85 (0.81, 0.89) per z score of dietary patt

33 k of fractures [HR (95% CI) for osteoporotic fractures: 0.90 (0.83, 0.96); for hip fractures: 0.85 (0

34 ation between cumulative exposure to TDF and fractures (1.08/5 y exposure; 0.94-1.25).

35 .15; 95% CI, 1.04-1.26; P < .05; aHR for hip fracture, 1.24; 95% CI, 1.05-1.47; P < .05) were each in

36 .43; 95% CI, 1.27-1.60; P < .05; aHR for hip fracture, 1.48; 95% CI, 1.18-1.85; P < .05), antipsychot

37 9.8% vs 18.4%), osteopenia (41.5% vs 43.1%), fractures (11.3% vs 18.6%), hospitalization (47.6% vs 42

38 7 per 1000 individuals) were lost due to hip fractures, 1230 (20.6%) of which were in the group aged

39 common in patients with chest trauma with CC fractures (13%, 15 of 114) versus patients with chest tr

40 reening, 11.1%; DXA screening, 9%; for wrist fractures, 14%, 17.8%, and 16.4%, respectively; for othe

41 -to-alendronate groups) and atypical femoral fracture (2 events and 4 events, respectively) were obse

42 .43; 95% CI, 1.15-1.77; P < .05; aHR for hip fracture, 2.14; 95% CI, 1.52-3.02; P < .05), and benzodi

43 %, 17.8%, and 16.4%, respectively; for other fractures, 22.6%, 30.8%, and 27.3%, respectively.

44 f Melody transcatheter pulmonary valve stent fracture (3.4%) and infectious endocarditis (4.3%) were

45 njury (15.1% vs 5.4%; P = .001), complex leg fractures (34.2% vs 18.5%; P = .001), Glasgow Coma Scale

46 versus patients with chest trauma without CC fractures (4%, 18 of 460) (OR, 3.72; 95% CI: 1.81, 7.64;

47 hours (35.6% vs 16.4%; P < .001), and pelvic fractures (43.8% vs 21.4%; P < .001); patients with VTE

48 diabetes (-14 cases [95% CI, -24 to -3), and fractures (-44 cases [95% CI, -71 to -13).

49 s were exchanged for the following reasons - fractures (5 patients, 3.2%), inflammation (2 patients w

50 diabetes (-19 cases [95% CI, -34 to -3]) and fractures (-53 cases [95% CI, -69 to -39]).

51 During hydraulic fracturing, a technique often used to extract hydrocarbo

52 n women identified to be at high risk of hip fracture, according to the FRAX 10-year hip fracture pro

53 s have been associated with atypical femoral fractures (AFFs), rare fractures with a transverse, brit

54 ], 1.39; 95% CI, 1.27-1.51; P < .05) and hip fracture (aHR, 1.43; 95% CI, 1.22-1.69; P < .05) before

55 ng feeding (resorption decreases) and recent fracture (all markers increase for several months).

56 creous sections can exhibit complete brittle fracture along the tablet interfaces at the proportional

57 Fracture analysis revealed significant associations betw

58 either C5aR1 or C5aR2 in a model of isolated fracture and after severe injury, combining the fracture

59 rentially regulate the immune response after fracture and are required for effective cartilage-to-bon

60 ed valve function and low incidence of stent fracture and endocarditis.

61 usal women with osteoporosis and a fragility fracture and randomly assigned them in a 1:1 ratio to re

62 There was no association between stent fracture and the primary end point (P=0.86) or with rest

63 Clinical outcomes evaluated were fractures and adverse events.

64 xperiments to measure the influence of macro-fractures and effective pressure on the permeability of

65 ven affected members exhibited frequent bone fractures and florid osseous dysplasia (p.Cys356Tyr), wh

66 The surface area and volume of both open fractures and high density fractures are calculated by 3

67 ty and turnover, but their effect on risk of fractures and osteonecrosis of the femoral head is less

68 uroSIDA participants were followed to assess fractures and osteonecrosis.

69 quality is a modifiable risk factor for bone fractures and osteoporosis, especially in low-income com

70 Here, we report secondary outcome data for fractures and post-hoc outcome data for falls.

71 images in the detection of nondisplaced hip fractures and to assess whether obtaining these images a

72 acic and lumbar vertebrae showed compression fractures and were electronically marked and classified

73 hes high-intensity events, such as hydraulic fracturing and flowback, from lower-intensity events, su

74 ation of organic chemicals used in hydraulic fracturing and their changes through time, from the prei

75 t MOF, 1579 (2.3%) sustained an incident hip fracture, and 8998 (13.1%) died.

76 wed by facial or orbital fracture, long bone fracture, and chest injury.

77 er GCS score, midline shift, depressed skull fracture, and epidural hematoma are key risk factors for

78 2 diabetes, gastrointestinal ulcers/bleeds, fractures, and cataracts (odds, 1.21-1.44 depending on t

79 From climate change to hydraulic fracturing, and from drinking water safety to wildfires,

80 We computed the Fx-GRS with 16 fracture- and BMD-associated variants, and the BMD-GRS w

81 Osteoporotic fractures are a leading cause of disability, costs, and

82 lume of both open fractures and high density fractures are calculated by 3-D counting.

83 Conclusion CC fractures are common in high-energy blunt chest trauma a

84 cts of teriparatide and denosumab on BMD and fractures are unclear (very low SOE), and these medicati

85 fied multiple bone mineral density (BMD) and fracture-associated loci.We conducted a study to evaluat

86 re the cumulative incidence of new vertebral fracture at 24 months and the cumulative incidence of cl

87 luded the incidences of nonvertebral and hip fracture at the time of the primary analysis.

88 calize, and categorize vertebral compression fractures at high sensitivity and with a low false-posit

89 to be associated with an increased risk for fractures at multiple sites.

90 ture (nonvertebral and symptomatic vertebral fracture) at the time of the primary analysis (after cli

91 ral dissolution and carbonation reactions in fractured basalts exposed to CO2-acidified fluids.

92 s of age or older who are at a high risk for fracture based on a discussion of patient preferences, f

93 also reduces risk for radiographic vertebral fractures, based on 1 trial.

94 Based on their fracture behavior, this technique is able to distinguish

95 5 years with previous surgical treatment for fractures below the knee who were undergoing removal of

96 of orthopedic implants used for treatment of fractures below the knee, a single preoperative dose of

97 of orthopedic implants used for treatment of fractures below the knee.

98 Raloxifene may prevent vertebral fractures but may not improve BMD (low SOE).

99 in blood have an increased risk of falls and fractures, but randomised trials of vitamin D supplement

100 These are resolved through transient DNA fracture by type II topoisomerases to permit chromosome

101 tive cartilage-to-bone transformation in the fracture callus and for undisturbed bone healing.

102 oblasts at the chondro-osseous border in the fracture callus, in a region we define as the transition

103 INTERPRETATION: Hip fracture can lead to a substantial loss of healthy life-

104 HCV coinfection, prior osteonecrosis, prior fracture, cardiovascular disease, and recent non-AIDS ca

105 Freeze-thaw induced fracturing coal by liquid nitrogen (LN2) injection exert

106 roughly 10 MDa to 200 kDa under typical HPT fracturing conditions.

107 Therefore, fracture conductivity will change dynamically during hyd

108 At last, the fracture connectivity is determined through comparison o

109 Fracture data were reported by general practitioners (me

110 type fully automated spinal segmentation and fracture detection software were then used to analyze th

111 inclusion criteria; 13.6% had a parental hip fracture diagnosis in administrative data during an aver

112 es are not equal in their predisposition for fracture due to the complex coupling between lattice geo

113 was less than 3000 N, or occurrence of first fracture (eg, hip, vertebral body, wrist).

114 nd proteinuria, and with deep-etching freeze-fracture electron microscopy, we resolved the ultrastruc

115 t-coated nanobubbles when examined by freeze-fracture electron microscopy.

116 dhesion, and absolute extensibility prior to fracture enable robust performance, along with mechanica

117 Subsequently, we measure the fracture energy for a bi-crystal of silicon carbide, dif

118 nt countries show variations of a shared hip fracture epidemic.

119 pair is important for understanding why some fractures fail to heal and for developing novel therapeu

120 groundwater fate and transport of hydraulic fracturing fluid compounds and mixtures remains a signif

121 Data were obtained with a slickwater fracturing fluid exposed to both a shale sample collecte

122 r changes through time, from the preinjected fracturing fluid to the produced water, was conducted.

123 lycyclic aromatic hydrocarbons, phthalates), fracturing fluids (e.g., quaternary ammonium biocides, 2

124 The corresponding percentages of vertebral fractures for DXA and quantitative CT with a 5-year inte

125 etched at both pHSW-T 7.7 and 7.4 and their fracture force reduced by 16 to 35%, respectively.

126 Exclusion criteria included open fractures, fractures involving the ankle joint, contrain

127 Agreement between parental hip fracture from offspring reports and diagnoses in adminis

128 oci.We conducted a study to evaluate whether fracture genetic risk score (Fx-GRS) and bone mineral de

129 nsional quantitative characterization of the fracture geometries.

130 tion of four horizontal wells with different fracture geometries.

131 pausal women during fracture repair surgery (fracture groups, n = 33) or total hip arthroplasty (nonf

132 time of the primary analysis (after clinical fractures had been confirmed in >/=330 patients).

133 However, the role of Scx in fracture healing has not yet been explored.

134 thods do not provide an objective measure of fracture healing or weight bearing for lower extremity f

135 and bone regeneration, resulting in delayed fracture healing.

136 es in cortical bone, as well as asymmetry in fracture healing.

137 role of Scx in cortical bone development and fracture healing.

138 mum (PM2.5) levels and osteoporosis-related fracture hospital admissions among 9.2 million Medicare

139 h high BMD, high SM, low BR, and low risk of fractures [HR (95% CI) for osteoporotic fractures: 0.90

140 release probability boutons, whereas freeze-fracture immunolocalization demonstrated only a 15% diff

141 No postoperative fractures, implant failures or loosening problems occurr

142 6; P = .03), whereas among patients with hip fracture, implementation was associated with increased r

143 lifestyle interventions aimed at preventing fracture, improving bone mineral density (BMD), or preve

144 teonecrosis and only 1 case of femoral shaft fracture in each group.

145 ficacy of alendronate to protect against hip fracture in older patients using glucocorticoids.

146 he first case of an isolated pterygoid plate fracture in the literature.

147 the incidence of new radiographic vertebral fractures in 1 high-quality trial.

148 nd characterized by bone fragility, frequent fractures in absence of trauma and growth deficiency.

149 nvestigate therapeutic avenues to treat bone fractures in children with autism.

150 low bone density and osteoporosis to prevent fractures in men and women.

151 ty-based screening intervention could reduce fractures in older women.

152 Use of these agents to reduce fragility fractures in patients with low bone mineral density is b

153 e range, 0.57-2.34 years), there were 27 hip fractures in the alendronate group and 73 in the no-alen

154 dimension analyses, how freeze-thaw induced fractures in the coal was quantitatively analyzed.

155 ed to explicitly model hydraulic and natural fractures in the reservoirs.

156 12.8% of postmenopausal women sustained hip fractures in their remaining life (no screening, 18.7%;

157 over 2.5-4.2 years did not prevent falls or fractures in this healthy, ambulatory, adult population.

158 n single-well performance with simple planar fractures in tight oil reservoirs.

159 ral therapy (ART), resulting in an increased fracture incidence that is largely independent of ART re

160 rocks' porous structure and the presence of fractures influence the transfer of fluids in the Earth'

161 These 2 predicted fracture initiation locations have some agreement with r

162 vels of adhesion and the morphologies of the fractured interfaces validated the sub-Tg, plasticity-in

163 Exclusion criteria included open fractures, fractures involving the ankle joint, contraindication to

164 Fracture is a complex trait, affected by both genetic an

165 Hydraulic fracturing is an industrial process allowing for the ext

166 brain injury, followed by facial or orbital fracture, long bone fracture, and chest injury.

167 While denosumab was found to reduce fractures, long-term survival data are still required.

168 tive fracture volume (fracture volume + near-fracture matrix porosity) by 56-65%.

169 Fracture mechanics concepts using double cantilever beam

170 In addition, fracture mechanics measurements showed that tissue from

171 Particularly in fracture mechanics, periodicities are of high scientific

172 nd temporal instability of two-phase flow in fractured media at the macroscopic scale.

173 , an efficient approach of Embedded Discrete Fracture Model (EDFM) was applied to explicitly model hy

174 The unusual fracture morphology suggests that bisphosphonate treatme

175 urces, it is possible to provide a seven-day fracture neck of femur service with no variation in thir

176 Fracture networks are quantitatively analyzed using a co

177 ths and the cumulative incidence of clinical fracture (nonvertebral and symptomatic vertebral fractur

178 One atypical femoral fracture occurred in each group during the extension.

179 Clinical fractures occurred in 198 of 2046 patients (9.7%) in the

180 Non-vertebral fragility fractures occurred in 25 (4.0%) patients in the teripara

181 At 24 months, new vertebral fractures occurred in 28 (5.4%) of 680 patients in the t

182 Total fracture was defined as first fracture of any type.

183 An isolated fracture of pterygoid plates without associated Le Fort

184 he jamming wave can also initiate widespread fracture of sea ice and further increase the likelihood

185 er with an acute, displaced, extra-articular fracture of the distal tibia, neither nail fixation nor

186 ASE REPORT: We present a case of an isolated fracture of the right lateral pterygoid plate by a penet

187 steoporosis of the hip and one with a stress fracture of the sacral bone.

188 Fractures of mid-face were first described by Le Fort an

189 ates without associated Le Fort fractures or fractures of other mid-face bones are exceedingly rare.

190 The best treatment for fractures of the distal tibia remains controversial.

191 ipping/plating process results in cracks and fractures of the solid electrolyte interphase, low Coulo

192 er return to the surface following hydraulic fracturing of deep shale formations to retrieve oil and

193 for the mobilization of arsenic in hydraulic fracturing operations and in groundwater systems contain

194 pterygoid plates without associated Le Fort fractures or fractures of other mid-face bones are excee

195 (OR, 6.8; 95% CI, 3.4-13.8), depressed skull fracture (OR, 6.5; 95% CI, 3.7-11.4), and epidural hemat

196 mong patients with CKD; and reported on BMD, fractures, or safety (mortality and adverse events).

197 d controlled trials were designed to examine fracture outcomes.

198 als who had one or more osteoporosis-related fractures over a 5-year period.

199 ectivity is determined through comparison of fracture parameters with permeability.

200 ormal hip cartilage donated by neck of femur fracture patients.

201 % CI, 6.5-13.9) and 27.2 (95% CI, 21.6-34.2) fractures per 1000 person-years, with an absolute rate d

202 exerts a significant positive effect on the fracture permeability enhancement of the coal reservoir.

203 The fracture porosity and aperture from ICT analysis perform

204 However, management of osteoporosis and fracture prevention strategies are often not addressed b

205 n of treatment will maximize the benefits of fracture prevention while minimizing potential harms of

206 fracture, according to the FRAX 10-year hip fracture probability.

207 e of grain boundary structure on interfacial fracture properties, such as the tensile strength and wo

208 mproved bone mass and dramatically decreased fracture rate in swaying mice, a model of global Wnt1 lo

209 ly adjudicated, multicenter study, the stent fracture rate was low and not associated with major adve

210 bal IL-6 inhibition in the early phase after fracture reduced systemic inflammation, the recruitment

211 ales, but its fundamental processes in rough fractures remain unclear.

212 cellular and molecular mechanisms underlying fracture repair is important for understanding why some

213 re obtained from postmenopausal women during fracture repair surgery (fracture groups, n = 33) or tot

214 ection and patients undergoing emergency hip fracture repair.

215 ndibular condyle development and during bone fracture repair.

216 sponsible for both normal bone formation and fracture repair.

217 Most such fractures require surgical fixation but outcomes are unp

218 Reproducibility of parameters that reflect fracture resistance was assessed by using the intraclass

219 dronic acid combined increased bone mass and fracture resistance when compared with treatment with zo

220 an important component of bone strength and fracture resistance.

221 en variation at the WNT16 and RSPO3 loci and fracture risk (P = 0.004 and 4.0 x 10-4, respectively).

222 perparathyroidism, vitamin D deficiency, and fracture risk after KT.

223 e appears to be associated with a 38% excess fracture risk among T2DM patients in the early stages of

224 rednisolone is associated with decreased hip fracture risk and adverse effects.

225 s to compare a screening programme using the Fracture Risk Assessment Tool (FRAX) with usual manageme

226 s greater than 3% (World Health Organization Fracture Risk Assessment Tool score, or FRAX), 10-year r

227 dairy pattern might be associated with lower fracture risk because of high BMD, high bending strength

228 meat pattern might be associated with higher fracture risk because of widened, unstable bones, indepe

229 tamin D status does not influence subsequent fracture risk in childhood.

230 on of vitamin D intake and serum levels with fracture risk in children under 6 years of age.

231 atic, community-based screening programme of fracture risk in older women in the UK is feasible, and

232 ologic treatment for osteoporosis and reduce fracture risk in postmenopausal women by up to 50%.

233 FRAX is a tool used to assess fracture risk in the general population.

234 porosis and related fractures, screening for fracture risk is not currently advocated in the UK.

235 ased on a discussion of patient preferences, fracture risk profile, and benefits, harms, and costs of

236 Fracture risk should be included among the consideration

237 Oral glucocorticoid treatment increases fracture risk, and evidence is lacking regarding the eff

238 Effects of osteoporosis medications on BMD, fracture risk, and safety among patients with CKD are no

239 Concerns have been raised about potential fracture risk, especially at the hip, spine and wrist.

240 genetically predicted grip strength on lower fracture risk.

241 during childhood, which could contribute to fracture risk.

242 er resulting in bone fragility and increased fracture risk.

243 ncreasing treatment gap for patients at high fracture risk.

244 e intake of calcium with vitamin D (CaD) and fracture risk.Data from 5823 white postmenopausal women

245 n to estimate the permeability of intact and fractured rocks, forming a basis to constrain fluid flow

246 with osteoporosis who were at high risk for fracture, romosozumab treatment for 12 months followed b

247 dications targeting osteoporosis and related fractures, screening for fracture risk is not currently

248 s resulted in low bone mass with spontaneous fractures similar to that observed in OI patients.

249 oximal femoral cortical bone adjacent to the fracture site were obtained from postmenopausal women du

250 vel terms (HLT) and preferred terms (PT) for fracture sites, defined by MedDRA (Medical Dictionary fo

251 a human cadaver comminuted metaphyseal tibia fracture specimen demonstrated over 2.25 mm of reproduci

252 tal-related events (SREs) such as pathologic fracture, spinal cord compression, or the necessity for

253 es but significantly reduces the interfacial fracture strength.

254 precipitates on Ga-embrittled intergranular fracture surfaces of AA5083.

255 te resulted in a significantly lower risk of fracture than alendronate alone.

256 atal 25(OH)D3 had lower odds of sustaining a fracture than did those in the lowest quintile (adjusted

257 njuries were more common in patients with CC fractures than in patients without CC fractures.

258 To fracture the rocks, a proprietary mix of chemicals is in

259 ased risk of kidney disease and osteoporosis/fracture, this risk did not seem to be dependent of pers

260 Slipped capital femoral epiphysis (SCFE), a fracture through the physis with resultant slip of the e

261 a significant elongation of 4-10% and a good fracture toughness (K1C) of 23.5-29.6 MPa m(1/2) were ob

262 The calculated Fracture toughness from both Griffith's theory and MD si

263 Fracture toughness measures the resistance of a material

264 ration factor and flexural strength with the fracture toughness of concretes is proposed.

265 based study could be vital in evaluating the fracture toughness of even opaque and complex heterogene

266 s indicate that the former over-predicts the fracture toughness of nc-silicene.

267 Grain boundaries typically dominate fracture toughness, strength and slow crack growth in ce

268 treated with bisphosphonates had deficits in fracture toughness, with lower crack-initiation toughnes

269 onary disease) and a surgical diagnosis (hip fracture treated with arthroplasty) in 2010.

270 plications in patients with displaced tibial fracture treated with intramedullary nail fixation vs lo

271 Qualitative similarities between hip fracture trends in different countries suggests variatio

272 -adjusted life-years (DALYs) lost due to hip fractures using real-life follow-up cohort data.

273 minerals, as expected, increasing effective fracture volume (fracture volume + near-fracture matrix

274 ected, increasing effective fracture volume (fracture volume + near-fracture matrix porosity) by 56-6

275 The difference between the fracture volume change recorded by the microtomography i

276 ced water composition could reduce effective fracture volume.

277 Total fracture was defined as first fracture of any type.

278 r FRAX), 10-year risk for major osteoporotic fracture was greater than 20% (FRAX), quantitative CT fe

279 than or equal to -2.5, 10-year risk for hip fracture was greater than 3% (World Health Organization

280 tients [10.6%]; P=0.04), and the risk of hip fracture was lower by 38% (41 of 2046 patients [2.0%] vs

281 Successful fracture was noted fluoroscopically when the waist of th

282 for interobserver agreement in detecting CC fractures was 0.65 (substantial agreement).

283 The 30-day mortality of patients with CC fractures was 7.02% (eight of 114) versus 4.78% (22 of 4

284 The risk of nonvertebral fractures was lower by 19% in the romosozumab-to-alendro

285 ific organic constituents in these hydraulic fracturing wastewaters is limited to hydrocarbons and a

286 igh because PW volumes can support hydraulic fracturing water demand based on 2014 data.

287 produced water (PW) management and hydraulic fracturing water demands based on detailed well-by-well

288 show that 37% of all recorded hydraulically fractured wells stimulated during 2014 exist within 2 km

289 cted between 2000 and 2014 and hydraulically fractured wells stimulated in 2014 in 14 states.

290 CC fractures were documented in 39.5% (45 of 114) of primar

291 agnosed celiac disease (diarrhea, anemia, or fracture) were associated with undiagnosed celiac diseas

292 cture and after severe injury, combining the fracture with an additional thoracic trauma.

293 with atypical femoral fractures (AFFs), rare fractures with a transverse, brittle morphology.

294 hose from patients with typical osteoporotic fractures with and without bisphosphonate treatment.

295 ous medium containing discretely distributed fractures with dynamic conductivities.

296 nd do not improve prediction of bone loss or fracture within an individual.

297 vitamin D supplements and decreased odds of fracture (yes vs. no: aOR = 0.42, 95% CI: 0.25, 0.69).

298 bone mineral density and increased risk for fracture, yet the cellular origin of the bone phenotype

299 ere detected in the vicinity of the Hornsund Fracture Zone, leading us to postulate that the gas asce

300 to postulate that the gas ascends along this fracture zone.