ライフサイエンスコーパス: fragilis

1 ated with the choA orthologue in Bacteroides fragilis.

2 dentified 1021 candidate glycoproteins of B. fragilis.

3 inal recolonization with either strain of B. fragilis.

4 a including Escherichia coli and Bacteroides fragilis.

5 irines were isolated from the sponge Dysidea fragilis.

6 RprY, a response regulator from Bacteroides fragilis.

7 bdominal abscess formation in response to B. fragilis.

8 s response important for aerotolerance of B. fragilis.

9 known virulence factor of enterotoxigenic B. fragilis.

10 metallo-beta-lactamase CcrA from Bacteroides fragilis.

11 those of Bacteroides thetaiotaomicron and B. fragilis.

12 a propria lymphocytes (LPLs), or Bacteroides fragilis.

13 previously determined PS A2 from Bacteroides fragilis.

14 xtracts of the obligate anaerobe Bacteroides fragilis.

15 function, associated with an increase in B. fragilis.

16 naerobic Gram-negative bacterium Bacteroides fragilis.

17 transmission of the trichomonad Dientamoeba fragilis.

18 echinoid, the sea urchin, Strongylocentrotus fragilis.

19 le for lipopolysaccharide biosynthesis in B. fragilis.

20 lori, Clostridium difficile, and Bacteroides fragilis.

21 We used 432 sequences (137 of O. fragilis, 215 of Ophiothrix sp. II, and 80 of Ophiothrix

22 ifunctional enzyme isolated from Bacteroides fragilis 9343, which converts l-fucose into GDP-fucose v

23 the ubiquitous gut microorganism Bacteroides fragilis, a bacterial polysaccharide (PSA) directs the c

24 s commensal anaerobes, including Bacteroides fragilis, a common and immunologically important commens

25 Bacteroides fragilis, a component of the normal intestinal flora, is

26 Homology searches indicated that the B. fragilis aconitase is most closely related to aconitases

27 that the prominent gut commensal Bacteroides fragilis activates the TLR pathway to establish host-mic

28 uced by the intestinal commensal Bacteroides fragilis, activates CD4+ T cells, resulting in a Th1 res

29 We studied the dissemination of B. fragilis after acute peritonitis and characterized the i

30 ingle gene, oxe (i.e., oxygen enabled) in B. fragilis allows for growth in concentrations as high as

31 ferrin as a model, it has been shown that B. fragilis alone can rapidly and efficiently deglycosylate

32 distribution and colonization of labeled B. fragilis along the intestine, as well as niche competiti

33 uired for GALT development, we introduced B. fragilis along with stress-response mutants of B. subtil

34 apsule biogenesis in E. coli and Bacteroides fragilis also depends on processive antiterminators but

35 as increased in YAMC cells incubated with B. fragilis, an effect mediated by lipopolysaccharide and o

36 Here we show that fragilis, an interferon-inducible transmembrane protein,

37 documenting the pathogenicity of Dientamoeba fragilis, an intestinal protozoan common in children.

38 e obligately anaerobic bacterium Bacteroides fragilis, an opportunistic pathogen and inhabitant of th

39 ative promoters, resulting in 188 hits in B. fragilis and 109 hits in F. johnsoniae.

40 e were untreated or treated with Bacteroides fragilis and antibiotic-mediated depletion of intestinal

41 e were untreated or treated with Bacteroides fragilis and antibiotic-mediated depletion of intestinal

42 The combination of Bacteroides fragilis and Bacillus subtilis consistently promoted GAL

43 to global public health such as Dientamoeba fragilis and Blastocystis hominis and how they too might

44 When intestinal integrity is disrupted, B. fragilis and colonic contents escape into the peritoneum

45 osylation is central to the physiology of B. fragilis and is necessary for the organism to competitiv

46 pports lipopolysaccharide biosynthesis in B. fragilis and is subject to feedback regulation by CMP-Kd

47 zinc metallo-beta-lactamase from Bacteroides fragilis and its complex with a biphenyl tetrazole inhib

48 xistence of two distinct species, Ophiothrix fragilis and Ophiothrix sp. II.

49 e considered human-specific; by contrast, D. fragilis and P. hominis have been isolated from domestic

50 O-glycosylation systems, that of Bacteroides fragilis and related species is unique in that extracyto

51 ures of various bacteria such as Bacteroides fragilis and Salmonella abortus are observed for CD14(+/

52 e of two distinct subfamilies of GH110 in B. fragilis and thetaiotaomicron strains.

53 h the promoter regions of nqrA genes from B. fragilis and Vibrio cholerae.

54 mM, while those of Bacteroides pyogenes, B. fragilis, and Akkermansia muciniphila were greater in th

55 ffects on Staphylococcus aureus, Bacteroides fragilis, and Candida albicans are investigated.

56 res containing Escherichia coli, Bacteroides fragilis, and Clostridium perfringens.

57 erium nucleatum, enterotoxigenic Bacteroides fragilis, and colibactin-producing Escherichia coli.

58 ructure-function relationships in Allosaurus fragilis, and have found that the skull was designed to

59 Ophiothrix fragilis appeared genetically isolated between the Atlan

60 ons of GA3 loci, GA3 T6SSs of the species B. fragilis are likely the source of numerous novel effecto

61 The ccf genes of B. fragilis are upregulated during gut colonization, prefer

62 half of the extracytoplasmic proteins of B. fragilis, are glycosylated.

63 We report a familial cluster of D. fragilis associated with marked peripheral eosinophilia

64 mposed of Omp121 and Omp71) from Bacteroides fragilis ATCC 25285 was purified and tryptic peptide seq

65 stimulating immunogen PS A1 from Bacteroides fragilis ATCC 25285/NCTC 9343 via a physiologically stab

66 umannii, Neisseria meningitidis, Bacteroides fragilis, Bacillus anthracis, Yersinia pestis, Francisel

67 homologs, allow corrected annotations for B. fragilis bfr and other dpsl genes within the bacterial d

68 en (GlyAg) polysaccharide A from Bacteroides fragilis but not conventional peptides.

69 E. coli provided strong synergy to B. fragilis but not to C. perfringens.

70 This defect was overcome by gavage with B. fragilis, by immunization with B. fragilis polysaccharid

71 istent with the observation that Bacteroides fragilis can colonize the colon in the absence of facult

72 Bacteroides fragilis can replicate in atmospheres containing </=0.05

73 -negative opportunistic pathogen Bacteroides fragilis, can rescue the ultraviolet sensitivity of an E

74 The Bacteroides fragilis capsular polysaccharide complex is the major vi

75 hanism is similar to that of the Bacteroides fragilis capsular polysaccharides and establishes DNA in

76 that is increased by MIA and restored by B. fragilis causes certain behavioral abnormalities, sugges

77 o a preferred target site in the Bacteroides fragilis chromosome by a transposon-encoded targeting pr

78 kb transfer factor isolated from Bacteroides fragilis clinical isolate LV23.

79 ted from an antibiotic resistant Bacteroides fragilis clinical isolate.

80 detect the bft gene subtypes in Bacteroides fragilis clinical isolates.

81 al gastrointestinal inhabitants: Bacteroides fragilis, Clostridium perfringens, Escherichia coli, Kle

82 Our results therefore demonstrate that B. fragilis co-opts the Treg lineage differentiation pathwa

83 s in mice; however, Fpn is dispensable in B. fragilis colitis, wherein host proteases mediate BFT act

84 Notably, the CCF system is required for B. fragilis colonization following microbiome disruption wi

85 immunomodulatory activities of PSA during B. fragilis colonization include correcting systemic T cell

86 TLR2 on CD4(+) T cells is required for B. fragilis colonization of a unique mucosal niche in mice

87 The symbiont Bacteroides fragilis constitutes a relatively small proportion (up t

88 fspring with the human commensal Bacteroides fragilis corrects gut permeability, alters microbial com

89 The human commensal Bacteroides fragilis delivers immunomodulatory molecules to immune c

90 Bacteroides fragilis-derived LPS, however, can effectively stimulate

91 -type UDP-GlcA decarboxylases of Bacteroides fragilis, designated BfUxs1 and BfUxs2.

92 duced by the commensal bacterium Bacteroides fragilis directs development of the immune system of the

93 hat a prominent human commensal, Bacteroides fragilis, directs the development of Foxp3(+) regulatory

94 Clinical isolates of B. fragilis displayed a greater capacity for growth under m

95 There are 2 classes of B. fragilis distinguished by their ability to secrete a zin

96 Detection of D. fragilis DNA inside Enterobius vermicularis eggs agrees

97 Although B. fragilis does not normally grow with manNAc as the sole

98 A PSA mutant of B. fragilis does not restore these immunologic functions.

99 ther the virulence mechanisms employed by B. fragilis during infections differ from those employed fo

100 dependent IL-10 production in response to B. fragilis during its pathogenic interactions with the hos

101 Here we demonstrate that B. fragilis encodes a cytochrome bd oxidase that is essenti

102 include common protozoa such as Dientamoeba fragilis, Entamoeba histolytica, or Cyclospora cayetanen

103 Our findings define a role for B. fragilis enterotoxin and its activating protease in the

104 ation between disease and the presence of B. fragilis enterotoxin.

105 (CNS), Peptostreptococcus spp., Bacteroides fragilis, Escherichia coli, Enterococcus spp., Pseudomon

106 Enterotoxigenic Bacteroides fragilis (ETBF) causes diarrhea and is implicated in inf

107 Enterotoxigenic Bacteroides fragilis (ETBF) has been implicated in inflammatory bowe

108 e, the bacterium enterotoxigenic Bacteroides fragilis (ETBF) is a significant source of chronic infla

109 human commensal enterotoxigenic Bacteroides fragilis (ETBF) is linked to both inflammatory bowel dis

110 Enterotoxigenic Bacteroides fragilis (ETBF) produces the Bacteroides fragilis toxin,

111 Enterotoxigenic Bacteroides fragilis (ETBF) secretes a 20-kDa metalloprotease toxin

112 enicity island (BfPAI) in enterotoxigenic B. fragilis (ETBF) strain 86-5443-2-2 and a related genetic

113 cter species and enterotoxigenic Bacteroides fragilis (ETBF), in 201 U.S. and European travelers with

114 n gut bacterium, enterotoxigenic Bacteroides fragilis (ETBF), to investigate the link between inflamm

115 The burden of enterotoxigenic Bacteroides fragilis (ETBF)-related diarrhea was determined in a bir

116 lonic bacterium, enterotoxigenic Bacteroides fragilis (ETBF).

117 those that do are called enterotoxigenic B. fragilis (ETBF).

118 or commensal bacterial Ags, in particular B. fragilis expressing polysaccharide A, in protecting agai

119 nd that addAB is required for survival of B. fragilis following DNA damage.

120 te such competition, we screened Bacteroides fragilis for the production of antimicrobial molecules.

121 Bacteroides fragilis, for example, synthesizes eight capsular polysa

122 Bacteroides fragilis GA3 is known to mediate potent inter-strain com

123 A Bacteroides fragilis gene (argF'(bf)), the disruption of which rende

124 5LIW1) is the only protein encoded by the B. fragilis genome with significant identity to any known A

125 1 is located in a conserved region of the B. fragilis genome, whereas Bfuxs2 is in the heterogeneous

126 mediate additional DNA inversions of the B. fragilis genome.

127 scan of the Flavobacterium johnsoniae and B. fragilis genomes for putative promoters, resulting in 18

128 Analysis of the B. fragilis genomic sequence, together with genetic conserv

129 hingolipids, we found that treatment with B. fragilis glycosphingolipids-exemplified by an isolated p

130 romonas species (11.3%), and the Bacteroides fragilis group (10.2%).

131 hingobacterium spp. (n = 3), and Bacteroides fragilis group (n = 15).

132 Members of the Bacteroides fragilis group are among the most common anaerobic bacte

133 More Bacteroides fragilis group bacteremias were detected only in the FN

134 ypically resemble members of the Bacteroides fragilis group but phylogenetically display >5% 16S rRNA

135 ptibility data of species of the Bacteroides fragilis group for 1989-1990 and 1998-1999 studies showe

136 in time to detection was greatest for the B. fragilis group: FN, 28 h, versus SN, 60.0 h.

137 One member of this family from Bacteroides fragilis had exquisite substrate specificity for the bra

138 ed from mice reconstituted with wild type B. fragilis had significantly enhanced rates of conversion

139 Here, we demonstrate that Bacteroides fragilis has a general O-glycosylation system.

140 The human gut symbiont Bacteroides fragilis has a general protein O-glycosylation system in

141 Fpn-deficient, enterotoxigenic B. fragilis has an attenuated ability to induce sepsis in m

142 hesis in the anaerobic bacterium Bacteroides fragilis has been purified and crystallized in space gro

143 The chromosome of Bacteroides fragilis has been shown to undergo 13 distinct DNA inver

144 Dientamoeba fragilis has emerged as an important and underrecognized

145 Among the Bacteroides spp. in the gut, B. fragilis has the unique ability of efficiently harvestin

146 pidemiology of enterotoxigenic strains of B. fragilis in clinical infections and whether there is a c

147 these findings for the pathophysiology of B. fragilis in extraintestinal infections and competition i

148 the number of IRs are active processes of B. fragilis in the endogenous human intestinal ecosystem.

149 n of polysaccharide A (PSA) from Bacteroides fragilis in the endosome depends on the APC's having an

150 er, the identification of a cyst stage of D. fragilis in the stool of rodents infected with a human i

151 case of metronidazole-resistant Bacteroides fragilis in the United States and demonstrate the presen

152 onocolonization of germ-free animals with B. fragilis increases the suppressive capacity of Tregs and

153 ated and complex colonized mice, and from B. fragilis-induced murine abscesses.

154 ry molecule of the gut commensal Bacteroides fragilis, induces regulatory T cells to secrete the anti

155 Dientamoeba fragilis infection should be considered in the setting o

156 and secondary outcome was eradication of D. fragilis infection.

157 uch as Staphylococcus aureus and Bacteroides fragilis initiate this host response when transferred to

158 containing Escherichia coli and Bacteroides fragilis into the abdomens of rats (n = 9).

159 The opportunistic pathogen Bacteroides fragilis is a commensal organism in the large intestine,

160 Dientamoeba fragilis is a common enteropathogen of humans.

161 The anaerobe Bacteroides fragilis is a gram-negative, opportunistic pathogen that

162 The anaerobe Bacteroides fragilis is a highly aerotolerant, opportunistic pathoge

163 ride A (PSA) from the capsule of Bacteroides fragilis is a potent activator of CD4(+) T cells and tha

164 Enterotoxigenic anaerobic Bacteroides fragilis is a significant source of inflammatory diarrhe

165 Dientamoeba fragilis is a single-celled protozoan, closely related t

166 identify an alternative pathway by which B. fragilis is able to reestablish capsule production and m

167 on or commensalism, induction of IL-10 by B. fragilis is critical to this microbe's interactions with

168 errin deglycosylation occurs in vivo when B. fragilis is propagated in the rat tissue cage model of e

169 Bacteroides fragilis is the leading cause of anaerobic bacteremia an

170 Bacteroides fragilis is the most common anaerobe isolated from clini

171 causing human gastrointestinal symptoms, D. fragilis is very common and is second only to Blastocyst

172 The obligate anaerobe, Bacteroides fragilis, is a highly aerotolerant intestinal tract orga

173 human intestinal microorganism, Bacteroides fragilis, is able to extensively modulate its surface.

174 e intestinal anaerobic symbiont, Bacteroides fragilis, is highly aerotolerant and resistant to H(2)O(

175 B. fragilis lacking PSA is unable to restrain T helper 17 c

176 naerobic, opportunistic pathogen Bacteroides fragilis lacks the glutathione/glutaredoxin redox system

177 w, self-transferable transfer factor from B. fragilis LV23 and that this new factor encodes a tetracy

178 cLV25 was isolated from B. fragilis LV25 by its capture on the nonmobilizable Esche

179 Recolonization with wild type B. fragilis maintained resistance to EAE, whereas reconstit

180 specific recombinase family, conserved in B. fragilis, mediate additional DNA inversions of the B. fr

181 tory molecule, polysaccharide A (PSA), of B. fragilis mediates the conversion of CD4(+) T cells into

182 ely, the two mobilization proteins of the B. fragilis mobilizable transposon Tn4399.

183 port that the intestinal microbe Bacteroides fragilis modifies the homeostasis of host invariant natu

184 an altered serum metabolomic profile, and B. fragilis modulates levels of several metabolites.

185 Upon challenge with B. fragilis, mortality rates and serum proinflammatory cyto

186 eletion of its gene resulted in the first B. fragilis mutant able to synthesize only one phase-variab

187 as the sole carbon source, we isolated a B. fragilis mutant strain that can grow on this substrate,

188 We previously showed that a Bacteroides fragilis mutant unable to synthesize 4 of the 8 capsular

189 this study, we analysed the phenotype of B. fragilis mutants with defective protein glycosylation an

190 they are functional paralogs and that the B. fragilis NCTC 9343 PSF repeat unit contains xylose.

191 fy the sphingolipids produced by Bacteroides fragilis NCTC 9343.

192 found in the genome sequences of Bacteroides fragilis NCTC9343 and Bacteroides thetaiotaomicron VPI54

193 found to be present in the genome of the B. fragilis NCTC9343 strain but absent in strains 638R, YCH

194 In animals harbouring B. fragilis not expressing PSA, H. hepaticus colonization l

195 The B. fragilis nrdA and nrdB genes were overexpressed in Esche

196 d indicate that during aerobic conditions B. fragilis NrdAB may have a role in maintaining deoxyribon

197 e that whereas both ETBF and nontoxigenic B. fragilis (NTBF) chronically colonize mice, only ETBF tri

198 ed the expression of bft in non-toxigenic B. fragilis (NTBF) strains.

199 that do not secrete BFT are nontoxigenic B. fragilis (NTBF), and those that do are called enterotoxi

200 ase indicates that amino acid residue 90 (B. fragilis numbering) plays an important role in conferrin

201 Three-dimensional modeling of B. fragilis Omp121 (based on 1D and 3D sequence profiles, c

202 ots of the deduced amino acid sequence of B. fragilis Omp121 display striking similarity with those o

203 evelop abscesses following challenge with B. fragilis or abscess-inducing zwitterionic polysaccharide

204 acterioferritin-related (bfr) gene in the B. fragilis oxidative stress response.

205 t into the role of individual Trxs in the B. fragilis oxidative stress response.

206 The genetic element flanking the Bacteroides fragilis pathogenicity island (BfPAI) in enterotoxigenic

207 The bft gene and the B. fragilis pathogenicity island (BfPAI) were cloned into N

208 oproteinase II (MPII)) are encoded by the B. fragilis pathogenicity island.

209 microbial biogeography within the colon, B. fragilis penetrates the colonic mucus and resides deep w

210 y recognized as human parasites: Dientamoeba fragilis, Pentatrichomonas hominis, Trichomonas vaginali

211 ort the cloning and overexpression of the B. fragilis phosphonopyruvate decarboxylase gene (aepY), pu

212 ge with B. fragilis, by immunization with B. fragilis polysaccharides, or by adoptive transfer of B.

213 upport routine metronidazole treatment of D. fragilis positive children with chronic gastrointestinal

214 F was isolated from 20.3% (40/197) of the B. fragilis-positive diarrheal specimens and from 8.1% (15/

215 l specimens and from 8.1% (15/185) of the B. fragilis-positive nondiarrheal specimens (P < .001) and

216 Of 382 B. fragilis-positive specimens, 14.4% of the strains found

217 Thus, B. fragilis possesses a new pathway of NANA utilization, wh

218 reactivity against Bacteroides vulgatus, B. fragilis, Prevotella intermedia, and, to a lesser extent

219 , but symptoms are relieved by a Bacteroides fragilis probiotic.

220 Bacteroides fragilis produces a capsular polysaccharide (PSA), which

221 ination, and we demonstrate that Bacteroides fragilis producing a bacterial capsular polysaccharide A

222 utes to sepsis in mice, and we identify a B. fragilis protease called fragipain (Fpn) that is require

223 In the gut, Bacteroides fragilis protects against colitis through induction of i

224 hat the prominent human symbiont Bacteroides fragilis protects animals from experimental colitis indu

225 r the human intestinal commensal Bacteroides fragilis, protects against central nervous system demyel

226 c calculations have demonstrated that the B. fragilis protein efficiently binds the internal Na(+) io

227 In B. fragilis, protein glycosylation is a fundamental and ess

228 C. perfringens and B. fragilis provided moderate synergy to each other but onl

229 In Bacteroides fragilis, PS synthesis is regulated so that only one of

230 y effects of the archetypal ZPS, Bacteroides fragilis PSA.

231 in the important human symbiont Bacteroides fragilis raised the critical question of how these molec

232 We reveal that Bacteroides fragilis releases PSA in outer membrane vesicles (OMVs)

233 toca, Staphylococcus aureus, and Bacteroides fragilis remains largely undefined and test availability

234 eria, Bifidobacterium longum and Bacteroides fragilis, representative members of the gut microbiota,

235 ion of the gnotobiotic mouse intestine by B. fragilis requires that the organism synthesize only a si

236 ns from Bacteroides vulgatus and Bacteroides fragilis respectively are members of the Pfam family PF1

237 stitution with polysaccharide A-deficient B. fragilis restored EAE susceptibility.

238 ccf genes in the model symbiont, Bacteroides fragilis, results in colonization defects in mice and re

239 ulated with Escherichia coli and Bacteroides fragilis (sepsis).

240 TTTG/TANNTTTG) were identical to Bacteroides fragilis sigma(ABfr) consensus -33/-7 promoter elements

241 mbiosis factor (PSA, polysaccharide A) of B. fragilis signals through TLR2 directly on Foxp3(+) regul

242 olation of the various species showed the B. fragilis species comprised 58% of the isolates in 1989 t

243 es of isolation of B. fragilis versus non-B. fragilis species had an overall effect on susceptibility

244 lysaccharides, or by adoptive transfer of B. fragilis-specific T cells.

245 lysaccharides of many strains of Bacteroides fragilis, Staphylococcus aureus, and Streptococcus pneum

246 be transferred from ETBF to nontoxigenic B. fragilis strains by a mechanism similar to that for the

247 tic colonization of mammals, we generated B. fragilis strains deleted in the global regulator of poly

248 5-nitroimidazole antimicrobial agents in B. fragilis strains from Europe and Africa.

249 he possibility of metronidazole-resistant B. fragilis strains in the United States and the importance

250 acteroidales strains analyzed, except for B. fragilis strains with the same T6SS locus.

251 y those cells with the highest expression of fragilis subsequently express stella, a gene that we det

252 lobal regulatory nature of the process in B. fragilis suggest an evolutionarily ancient mechanism for

253 Rickenellaceae, Parabacteroides, Bacteroides fragilis, Sutterella, Lachnospiraceae, 4-methyl-2-pentan

254 oles between the two species (as Bacteroides fragilis switches roles between humans and mice)(2).

255 A single strain of Bacteroides fragilis synthesizes eight distinct capsular polysacchar

256 Bacteroides fragilis synthesizes eight distinct capsular polysacchar

257 e (Bacteroides thetaiotaomicron, Bacteroides fragilis, Tannerella forsythensis, Porphyromonas gingiva

258 Enterotoxigenic Bacteroides fragilis that secrete a zinc-dependent metalloprotease t

259 ributing to the pathogenicity of Bacteroides fragilis, the most common anaerobic species isolated fro

260 In this study, the six B. fragilis thioredoxins (Trxs) were investigated to determ

261 as the time required (foraging time) for S. fragilis to approach its preferred food (giant kelp) in

262 ngs the total of oxyR-controlled genes in B. fragilis to five and suggests the existence of a second

263 of these genes eliminates the ability of B. fragilis to grow on NANA.

264 e stress are physiological adaptations of B. fragilis to its environment that enhance survival in ext

265 role of the C-terminal region in Bacteroides fragilis toxin (BFT) activity, processing, and secretion

266 ETBF that secretes B. fragilis toxin (BFT) causes human inflammatory diarrhea

267 The B. fragilis toxin (bft) gene from ETBF strain 86-5443-2-2 (

268 ependent metalloprotease toxin termed the B. fragilis toxin (BFT) have been associated with acute dia

269 The Bacteroides fragilis toxin (BFT) is the only known virulence factor

270 zinc-binding metalloprotease in Bacteroides fragilis toxin (BFT) processing and activity, the zinc-b

271 We now demonstrate that purified B. fragilis toxin (BFT) up-regulates SMO in HT29/c1 and T84

272 xpression of biologically active Bacteroides fragilis toxin (BFT), we studied the expression of bft i

273 own ETBF virulence factor is the Bacteroides fragilis toxin (BFT), which induces E-cadherin cleavage,

274 ethal disease from ETBF colonization in a B. fragilis toxin (BFT)-dependent manner.

275 tes a 20-kDa metalloprotease toxin termed B. fragilis toxin (BFT).

276 e a zinc-dependent metalloprotease toxin, B. fragilis toxin (BFT).

277 Enterotoxigenic strains that produce B. fragilis toxin (BFT, fragilysin) contribute to colitis a

278 des fragilis (ETBF) produces the Bacteroides fragilis toxin, which has been associated with acute dia

279 Expression of the B. fragilis trxB gene was induced following treatment with

280 Unlike the other described Tsrs of B. fragilis, Tsr19 brings about inversion of two DNA region

281 onserved ICE and are confined to Bacteroides fragilis Unlike GA1 and GA2 T6SS loci, most GA3 loci do

282 The data provided herein suggest that B. fragilis uses N-succinyl-L-ornithine rather than N-acety

283 pathway for binuclear CcrA from Bacteroides fragilis using density functional theory based quantum m

284 The prevalence of D. fragilis varies between 0% to over 82%; results depend o

285 This change in rates of isolation of B. fragilis versus non-B. fragilis species had an overall e

286 MPII and FRA is required for the overall B. fragilis virulence in vivo.

287 B. fragilis was anergistic (antagonistic) to E. coli in coi

288 te-specific recombinase (Tsr) of Bacteroides fragilis was characterized.

289 Eradication of D. fragilis was significantly greater in the metronidazole

290 et, the zinc beta-lactamase from Bacteroides fragilis, was screened against the fragment-like subset

291 ther our understanding of DNA transfer in B. fragilis, we isolated and characterized a new transfer f

292 onses specific for B. thetaiotaomicron or B. fragilis were associated with the efficacy of CTLA-4 blo

293 biosynthesis locus promoters of Bacteroides fragilis were determined from bacteria grown in vitro, f

294 B. fragilis, which by itself is immunogenic, did not promot

295 unistic human anaerobic pathogen Bacteroides fragilis, which is currently classified as a nonhemolyti

296 aracterized the nanLET operon in Bacteroides fragilis, whose products are required for the utilizatio

297 s against CTLA-4 favored the outgrowth of B. fragilis with anticancer properties.

298 TBF) strains, a nontoxigenic WT strain of B. fragilis (WT-NTBF), WT-NTBF overexpressing bft (rETBF),

299 ia coli, Neisseria meningitidis, Bacteroides fragilis, Yersinia pestis, Chlamydia trachomatis, Porphy

300 ons of the dinuclear form of the Bacteroides fragilis zinc beta-lactamase.