ライフサイエンスコーパス: fragmentation

1 poxemia, respiratory disturbances, and sleep fragmentation).

2 ce interval, 1.01 to 1.07 per 1% increase in fragmentation).

3 imately 16660 bp in length) without previous fragmentation.

4 anomeric memory of the glycosidic bond upon fragmentation.

5 most likely due to fire suppression and land fragmentation.

6 electron microscopy confirmed mitochondrial fragmentation.

7 and is dependent on patterns of land use and fragmentation.

8 deprotonated molecule [M-H](-) and its MS(4) fragmentation.

9 voirs) occurred mostly in hotspots of forest fragmentation.

10 hout Amadori rearrangement product and sugar fragmentation.

11 he sequence and structure constraints of RNA fragmentation.

12 minal ends of the protein with less internal fragmentation.

13 membrane, eventually inducing mitochondrial fragmentation.

14 , whereas PTSD risk is increased with social fragmentation.

15 ow might have been reduced following habitat fragmentation.

16 by collision-induced dissociation (CID)-MS3 fragmentation.

17 tion, oxidation, glycosylation variants, and fragmentation.

18 conservative approaches lead to unnecessary fragmentation.

19 and fragment ions without isolation prior to fragmentation.

20 poxemia, respiratory disturbances, and sleep fragmentation.

21 a monopole crystal, which exhibits magnetic fragmentation.

22 to mitochondria, and prevented mitochondrial fragmentation.

23 plant migration and the impacts of landscape fragmentation.

24 ng accurate mass, isotopic pattern and MS/MS fragmentation, 167 precursors, 89 as monoglycosylated an

25 showed reduction in total sleep time, sleep fragmentation, abnormal short non-rapid eye movement - r

26 ntly enhances proteomics analysis in all-ion fragmentation acquisition.

27 ity-density curves and showed that landscape fragmentation affected the shape of density dependence.

28 To explore how habitat fragmentation affects species persistence in food webs,

29 (HRMS) alone or in combination with all-ion-fragmentation (AIF), data-independent-acquisition (DIA),

30 pectrometry (MS), as well as MS upon all-ion fragmentation (AIF-MS).

31 poxemia, hemodynamic fluctuations, and sleep fragmentation, all of which could damage cerebral gray m

32 of these sheets is generally limited due to fragmentation along fault lines during chemical oxidatio

33 results from database searches and in silico fragmentation analyses and places these results into a r

34 study, we characterized marked mitochondrial fragmentation and abnormal mitochondrial distribution in

35 The FFPE process results in fragmentation and chemical modification of RNA, renderin

36 sive plants and natural enemies; (f) habitat fragmentation and coalescence that promote homogeneous,

37 he location of k -mers, which can cause data fragmentation and consequently inferior model performanc

38 led a global dataset on species responses to fragmentation and developed a statistical approach for q

39 -1 treatment could rescue both mitochondrial fragmentation and distribution deficits and improve mito

40 L-OPA1 cleavage is observed in mitochondrial fragmentation and dysfunction.

41 oung 3xTg mice strongly promotes APP and tau fragmentation and facilitates amyloid plaque deposits an

42 he contrasting phenomena of cortical network fragmentation and global synchronization, respectively.

43 notation, exon level differences, transcript fragmentation and incorrect gene annotation, which we su

44 ed as deposition solvent, TATP tends to show fragmentation and is not only detected as [M+NH4](+) but

45 ary driver of extinction, global patterns of fragmentation and its relationship to extinction risk ha

46 py and electron microscopy indicates nuclear fragmentation and membrane disruption of C. neoformans c

47 We observed particle fragmentation and morphological changes in microcrystals

48 eves these gains through improved quality of fragmentation and MS/MS success rates for all precursor

49 ative potential, and increased neuromuscular fragmentation and occasional denervation.

50 Combining these approaches with mass fragmentation and phloroglucinolysis allowed us to descr

51 Centrosome fragmentation and precocious centriole disengagement dep

52 estrictive RV and incomplete remodeling (QRS fragmentation and previous pulmonary valve replacement)

53 previously reported increased mitochondrial fragmentation and reduced ATP and mtDNA copy number in F

54 ly, VPS35 D620N mutant-induced mitochondrial fragmentation and respiratory deficits could be rescued

55 odel, but we find no correlation between DNA fragmentation and sample age over the timespans analyzed

56 mechanisms of modular organization: network fragmentation and subgroup cohesion.

57 get for interventions that may prevent sleep fragmentation and the attendant cardiovascular and cogni

58 hermore, activation of microglial cells, DNA fragmentation, and apoptosis of infected or uninfected c

59 apacity based on migration potential, forest fragmentation, and propagule pressure.

60 p yields, minimize land clearing and habitat fragmentation, and protect natural lands could increase

61 Duplication of services, fragmentation, and resource limitations may have impeded

62 ined by collision-induced dissociation MS/MS fragmentation, and the peptide backbone information was

63 garding average information entropy, opinion fragmentation, and the range of rumor spread.

64 fined as pain, visible hematuria, migration, fragmentation, and urinary tract infections (UTIs) withi

65 and an untargeted MS(2) experiment (all ion fragmentation) applying high collision energy.

66 ds, making it a valuable new tool for hybrid fragmentation approaches.

67 astructure development and resulting habitat fragmentation are expanding in Neotropical forests, and

68 ds to a loss of adhesion measured by dispase fragmentation assay (lambda = 15.1 min).

69 In adjusted analyses, greater sleep fragmentation associated with increased ESRD risk (hazar

70 tion indicates that the state of continental fragmentation at a given time is positively correlated w

71 from retraction of dendrites by thinning and fragmentation at the tips of dendrite branches, leading

72 We compared the five different ways of fragmentation available on a tribrid mass spectrometer a

73 is enabled in-depth targeted analysis of the fragmentation behavior of 1065 cross-linked precursors u

74 tle information regarding the ionization and fragmentation behavior of peroxy acids in mass spectrome

75 By exploiting the specific fragmentation behavior of pyrophosphorylated peptides du

76 ond to natural read duplicates likely due to fragmentation bias.

77 rmacological compounds known to elicit Golgi fragmentation: brefeldin A, golgicide A, and monensin.

78 ture of collision-induced dissociation (CID) fragmentation, but targeted analysis of MS1 pairs using

79 includes cell fixation and lysis, chromatin fragmentation by sonication, ChIP, proximity ligation wi

80 zation technique and mass analysis (MS) with fragmentation by tandem mass spectrometry (MS(2) ) and a

81 he precursor scan (MS1) are not selected for fragmentation by the instrument and therefore remain uni

82 se abnormalities, we inhibited mitochondrial fragmentation by the treatment of mitochondrial division

83 the high RLS is the result of lower particle fragmentation by zooplankton, likely due to the almost c

84 determine whether mitochondrial fission and fragmentation can be an adaptive mechanism used by the h

85 hacrylate (BMA) from a reversible addition - fragmentation chain transfer (RAFT) chain transfer agent

86 Photoactivated reversible addition fragmentation chain transfer (RAFT)-based dynamic covale

87 surface-confined aqueous reversible addition-fragmentation chain transfer (SCARAFT) polymerization me

88 ticles following a RAFT (reversible addition-fragmentation chain transfer) polymerization protocol.

89 er insertion (SUMI) into reversible addition-fragmentation chain-transfer (RAFT) agents.

90 of a bifunctional ROAMP-reversible addition-fragmentation chain-transfer (RAFT) initiator complex.

91 nduced electron transfer-reversible addition-fragmentation chain-transfer polymerization), synthetic

92 s of this species and, according to their MS fragmentation, clustered in flavonol-3-O-di-/tri-glycosi

93 tion; and alkaloids, through three-component fragmentation-coupling reactions.

94 Primary magmatic fragmentation creates a population of pyroclasts through

95 ny of its characteristics, such as extensive fragmentation, damage and contamination, can influence d

96 ins accurate mass, retention time, and MS/MS fragmentation data as well as annotations of all credent

97 -down identifications obtained using the MS2 fragmentation data.

98 ons, are identified using precursor mass and fragmentation data.

99 idence of mitophagy, including mitochondrial fragmentation, decreased mitochondrial content and mitoc

100 In response to severe injury, mitochondrial fragmentation developed in parallel with dendritic damag

101 cular adipocytes, with mitochondrial network fragmentation, disorganised cristae, and increased autop

102 r extensive study shows that natural habitat fragmentation does not result in negative genetic effect

103 Habitat fragmentation due to mega-wetlands extinction, and clima

104 oton microscopy, we quantified mitochondrial fragmentation during acute pathological conditions that

105 esistance within the channels and the faster fragmentation during dissolution of these tablets.

106 retained following gas-phase glycosidic bond fragmentation during tandem mass spectrometry (MS(2)).

107 ble precursors to difluoroenolates following fragmentation during the release of trifluoroacetate; ho

108 ting large populations buffered from habitat fragmentation, edge effects and human pressures.

109 Peptide sequencing after MS/MS fragmentation enabled the identification of 116 differen

110 UHPLC-MS/MS and improved the separation and fragmentation enabling sensitive detection.

111 ensitivity since the ion counts for a single fragmentation event are often low.

112 ure is closely linked to their function, and fragmentation (fission) of the normally elongated mitoch

113 However, owing to the exhaustive fragmentation following EI ionization, despite the use o

114 ened, and provide maps of global hotspots of fragmentation for the world's terrestrial mammals.

115 -component tandem oxidative cyclization with fragmentation from a 1,3-dicarbonyl compound to produce

116 ty in fluorine functionalization is fluoride fragmentation from the radical anion of the multifluorin

117 quantify the degree of attrition (secondary fragmentation) from grain size data.

118 ophic rank hypothesis, both habitat loss and fragmentation generally cause species extinction, with s

119 Species with higher fragmentation had smaller ranges and a lower proportion

120 Similarly, habitat fragmentation has almost no influence on the site occupa

121 thesis that temporal patterns of continental fragmentation have impacted global Phanerozoic biodivers

122 f variable length were used to study CMV DNA fragmentation in 20 SOTR plasma samples, viral stocks (T

123 in mouse brain, we quantified mitochondrial fragmentation in a full spectrum of cortical injuries, r

124 recently described phenomenon of chromosome fragmentation in a single catastrophic event.

125 inhibiting fungal caspase activation and DNA fragmentation in the murine lung.

126 i, due to considerable historical population fragmentation in this environment.

127 rd and have many limitations, including care fragmentation, inadequate communication among clinicians

128 factor highlights two loop regions for which fragmentation increases upon UVPD, signaling an increase

129 Indeed, the fragmentation induced a significant increase of ROS in h

130 Last, we show that Golgi fragmentation induced by ilimaquinone and nocodazole is

131 e is known about how habitat configurational fragmentation influences multi-trophic food web dynamics

132 cation using CCS databases and TWIMS-derived fragmentation information.

133 ed by detection of monochlorinated byproduct fragmentation ions using flow injection analysis with or

134 FT) scans, which produced intense ADP-ribose fragmentation ions.

135 Forest fragmentation is a ubiquitous, ongoing global phenomenon

136 Habitat fragmentation is generally considered to have negative e

137 between global biodiversity and continental fragmentation is not readily attributable to commonly ci

138 Although habitat fragmentation is often assumed to be a primary driver of

139 ggest that divergence in isolation following fragmentation is the dominant process structuring geneti

140 -1.1 mutants exhibit increased mitochondrial fragmentation leading to decreased rate of oxidative pho

141 CCCP-induced mitochondrial fragmentation leads to Mfn2 and LC3 co-localization with

142 Match leverages the most extensive in silico fragmentation libraries of freely available software.

143 anning 56 lipid types contained in in silico fragmentation libraries.

144 erimental and theoretical evidence that both fragmentations may involve the generation of acyl cyanid

145 human populations, urbanization, and forest fragmentation, may have altered the ecological niche of

146 escence turn-ON mechanism with a domino-like fragmentation mechanism.

147 y of these reactions occur via charge-remote fragmentation mechanisms.

148 h precursor and fragment ions as well as the fragmentation mechanisms.

149 This tandem photochemical, beta-fragmentation method promises to be useful for site-spec

150 charge states investigated and was the only fragmentation method to localize all eight phosphosites

151 higher-energy collision dissociation (EThcD) fragmentation methods when determining ADP-ribose accept

152 chanistically, mdivi-1 reduced mitochondrial fragmentation, mitochondrial dysfunction and oxidative s

153 LC-QTOF-MS data were acquired in All-Ions fragmentation mode in both positive and negative electro

154 In doing so, the burden of fragmentation model definition shifts from programmer to

155 we demonstrate that region-specific receptor fragmentation modifies channel regulation.

156 multiple reaction monitoring with multistage fragmentation (MRM(3)) and differential mobility spectro

157 is treated quantum mechanically and neither fragmentation nor system-specific adjustment is necessar

158 This phenotype was distinct from the Golgi fragmentation observed in apoptosis.

159 The transient fragmentation observed in the mild photo-damage model wa

160 on velocities >7 m/s, droplet separation and fragmentation occurred, resulting in incomplete mixing.

161 ations and reactivity data suggest that beta-fragmentation occurs much faster, implying the consumpti

162 Alternatively, Grob-type oxidative fragmentation of a 2-oxoglutarate-derived intermediate o

163 rbits (Taurid Complex) that was generated by fragmentation of a large short-period comet within the i

164 gioselective oxidation, dehydrogenation, and fragmentation of alkanes.

165 ency and minimizing primary ion beam-induced fragmentation of analytes, ME-SIMS has proven useful for

166 isobaric cross-linked species, an incomplete fragmentation of cross-linked products, and low-mass acc

167 08 SE), which accounted for both erosion and fragmentation of dead colonies.

168 Remarkably, sufficient fragmentation of doubly charged precursors could be achi

169 Fragmentation of epimers can enhance their identificatio

170 inding to LC3s/GABARAPs is essential for the fragmentation of ER tubules and their delivery to lysoso

171 on family members have the ability to induce fragmentation of ER tubules during starvation.

172 ong isoform of RTN3 is sufficient to trigger fragmentation of ER tubules.

173 of synaptic gephyrin is associated with the fragmentation of gephyrin in subsynaptic nanodomains.

174 tafluoropropen-2-olate, generated from a new fragmentation of hexafluoroisopropanol with a mixed Mg/L

175 d young adults as well as the complexity and fragmentation of HIV care and related services.

176 In the first stage, fragmentation of initial PuO2 particles provides larger

177 llision induced dissociation (FISCID) yields fragmentation of ions, which reduces sample complexity a

178 Here we show that fragmentation of large, imperfect crystals into microcry

179 gions clustering together, and the degree of fragmentation of left hemisphere networks.

180 nditions in the PTR-ToF-MS lead to extensive fragmentation of levoglucosan and cis-pinonic acid, whil

181 nable as the dissolution procedure initiates fragmentation of lignin prior to light exposure.

182 To date, fragmentation of mitochondria was studied either in diss

183 This is mainly due to poor fragmentation of modified peptides.

184 is challenging in processed foods due to the fragmentation of most biomarkers including DNA.

185 global process contributing to the loss and fragmentation of natural habitats.

186 The projectile hypothesis also explains the fragmentation of oil droplets with time, which occurred

187 -ribose moiety were used to trigger targeted fragmentation of only the modified peptides.

188 known fragmentation rules of lipids into the fragmentation of oxidized lipids.

189 proven to be well-suited for activation and fragmentation of peptides and proteins in ion trap mass

190 to potentiate thrombus instability, through fragmentation of platelet thrombi and/or enhanced endoge

191 Based on the MS/MS fragmentation of the aldehyde- and ketone-DNPH derivativ

192 l appearance similar to hard drusen, whereas fragmentation of the central and basal contents was seen

193 The end of germination coincides with fragmentation of the chondriome, doubling of mitochondri

194 tic intermediates, as well as homolytic bond fragmentation of the edge functional groups upon heating

195 respective organelles, as exemplified by the fragmentation of the Golgi apparatus (effector function)

196 feldin A treatment and abnormal swelling and fragmentation of the Golgi apparatus.

197 pe I photocleavage of a ketone (7b) and beta-fragmentation of the initially formed alkyl radical (8b)

198 The fragmentation of the material into increasingly smaller

199 Fragmentation of the oxetane via Lewis acid-activation r

200 Fragmentation of the resulting anionic product yields fa

201 ttack of hydroxide on the ketone followed by fragmentation of the resulting oxyanion into the carboxy

202 This is accompanied by apparent fragmentation of the TGN and redistribution of K15P to a

203 Fragmentation of the thermometer ion using DAII was inle

204 entrality (eigenvector and distance-weighted fragmentation) of habitat patches can help design better

205 ressed that the influence of natural habitat fragmentation on an evolutionary timescale should not be

206 lationships between land cover diversity and fragmentation on the within-field spatial associations o

207 out the need for complex sample preparation, fragmentation or purification.

208 rombolysis, percutaneous mechanical thrombus fragmentation, or percutaneous or surgical embolectomy-i

209 s population structure and find that habitat fragmentation owing to a natural barrier has resulted in

210 ther, these results suggest that continental fragmentation, particularly during the Mesozoic breakup

211 MS/MS spectra enables the generalization of fragmentation pathways, which is then used for the diffe

212 To explain this fragmentation pattern in trans double bonds, we have pro

213 study, we investigated and characterized the fragmentation pattern of a synthetically prepared dityro

214 We then detailed the fragmentation pattern of dityrosine cross-linked Abeta(1

215 action monitoring of a sphingolipid specific fragmentation pattern.

216 structures based on their mass and predicted fragmentation pattern.

217 ray ionization high-resolution MS, and their fragmentation patterns (MS/MS spectra) were identified.

218 The collision-activated dissociation (CAD) fragmentation patterns (obtained in MS(2) and MS(3) expe

219 ample complexity associated with overlapping fragmentation patterns and provides structural informati

220 d phytyl-purpurin-18 a has allowed to obtain fragmentation patterns associated with their different s

221 isomers by virtue of the differences in the fragmentation patterns at the carbon-carbon single bonds

222 The MS/MS spectra of the peroxy acids showed fragmentation patterns clearly different from the corres

223 eatures, the three molecules led to distinct fragmentation patterns depending on the position of the

224 uadrupole Time-of-Flight GC-MS (GC-QTOF) and fragmentation patterns from electronic impact and positi

225 elopment of computational tools that predict fragmentation patterns in silico and compare these to ex

226 steine residues, identification of gas-phase fragmentation patterns of endogenous dityrosine cross-li

227 re not sufficient for this purpose since the fragmentation patterns of small molecules can vary in di

228 In addition, the EID fragmentation patterns reflect the structural similariti

229 ted on commercial instruments do not provide fragmentation patterns that allow elucidation of certain

230 ed monohexosylceramides by mass spectrometry fragmentation patterns that distinguished alpha- from be

231 ventional activation methods do not generate fragmentation patterns that permit the simultaneous disc

232 To study their fragmentation patterns, we synthesized 12 peroxy acids w

233 he molecular ions but also exhibiting unique fragmentation patterns.

234 are adequately characterized based on their fragmentation patterns.

235 p duration (per hour less) and greater sleep fragmentation (per 1% more) each associated with greater

236 bon sink by increasing tree mortality, while fragmentation persistently offset the sink and turned ma

237 Drp1-induced mitochondrial fragmentation prevented replication of C. trachomatis ev

238 are consistent with the nucleophile-assisted fragmentations proceeding through an inversion transitio

239 Specifically, we have implemented a two-step fragmentation process in the inject flatapole device, wh

240 thway via a ring-opening mechanism (addition-fragmentation process), leading to the introduction of f

241 Applications of the proposed process include fragmentation processes or directed cascading diffusion

242 Instead, fragmentation produces polyfunctional low molecular weig

243 The products change from reactive fragmentation products in a higher temperature, higher d

244 The fragmentation products result from reactive ion-molecule

245 he environment, where they undergo very slow fragmentation (projected to take centuries) into small p

246 is also evidence to suggest that continental fragmentation promotes increasing marine richness, but t

247 n a product-dependent manner, and the unique fragmentation properties of the ADP-ribose moiety were u

248 ropose a model for ancient DNA decay wherein fragmentation rapidly reaches a threshold, then subseque

249 The reversible ring-opening addition and fragmentation reaction of p-cresol-based N-phenylbenzoxa

250 periments, demonstrating that copper-induced fragmentation reactions can potentially identify differe

251 potential of copper(II) to induce gas-phase fragmentation reactions in macrotetrolides, a class of p

252 , copper(II) was also used to induce radical fragmentation reactions in the carboxylic acid polyether

253 l radical anion using radical triggered C-Br fragmentation reactions.

254 It is well known that forest fragmentation reduces fecundity in several avian species

255 tion, including Drp1-dependent mitochondrial fragmentation, reduction in mitochondrial membrane poten

256 aximal exercise, physiological mitochondrial fragmentation results in enhanced, rather than impaired,

257 c compounds being ionized with limited or no fragmentation, retaining the molecular ion, has been of

258 Accurate mass fragmentation rules are combined with in silico spectra

259 Application of these generic fragmentation rules of dityrosine cross-linked peptides

260 analyzed by translating experimentally known fragmentation rules of lipids into the fragmentation of

261 In the all ion fragmentation scan, a diagnostic fragment originating fr

262 We describe optimized fragmentation schemes and data analysis strategies subst

263 The fragmentation selectivities could be correlated with the

264 The aryl/methyl fragmentation selectivities for phenyltrimethylstannane

265 The aryl/methyl fragmentation selectivities for the photooxidations of p

266 e neutral codonors, which thereby affect the fragmentation selectivities.

267 ve, neutral or positive) to habitat loss and fragmentation separately, depending on their dispersal r

268 ra, such as the CID/UVPD pairs, into peptide fragmentation site predictions.

269 metabolites, wrapper functions for in silico fragmentation software, nearest neighbor chemical simila

270 is study, we explore the role that secondary fragmentation, specifically attrition, has in transformi

271 enhance peak capacity, spectral clarity and fragmentation specificity.

272 uctures ("Mass2Motifs") from a collection of fragmentation spectra as sets of co-occurring molecular

273 nd blood group isomers, which have identical fragmentation spectra, exhibit very distinctive IM drift

274 re to automatically learn from and interpret fragmentation spectra, provided a representative set of

275 onfirmed using isotopic simulation and MS-MS fragmentation spectra.

276 Fragmentation substantially augments carbon emissions fr

277 h collision energies, which are required for fragmentation, suggest substantial thermal stability of

278 h cleaved caspase-3 (CC3) activation and DNA fragmentation (TdT-mediated dUTP nick-end labeling [TUNE

279 -specifically modified peptides by different fragmentation techniques shows that pyrophosphorylated p

280 ) and electron capture dissociation (ECD) as fragmentation techniques, and D-alpha-tocopheryl polyeth

281 al MS settings, we also assessed the peptide fragmentation techniques, including higher-energy collis

282 1065 cross-linked precursors using the five fragmentation techniques: collision-induced dissociation

283 -cytokeratin IHC stainings to quantify tumor fragmentation (TF), a measure of tumor invasiveness of l

284 newly developed algorithm based on molecular fragmentation to automatically extract reactive chemical

285 hic and quantum chemical studies reveal that fragmentation to give ethylene is promoted by binding of

286 TR-Seq employs in vitro CRISPR-Cas9-targeted fragmentation to produce specific DNA molecules covering

287 are consistent with a model of unimolecular fragmentation to yield free phosphinidene [(i)Pr2N horiz

288 Reversible addition-fragmentation type degenerative chain transfer contribut

289 However, fragmentation usually occurs at the N-terminal and C-ter

290 Mitochondrial network fragmentation was also confirmed as an early event of re

291 The degree of lipid fragmentation was determined experimentally at varying l

292 In moderate and mild injury, mitochondrial fragmentation was reversible with full recovery of struc

293 combined gas-phase separation and subsequent fragmentation, we could eliminate the need for authentic

294 Land cover diversity and fragmentation were more explanatory than land cover type

295 enrichment, 3 linker ligation steps, and RNA fragmentation, which can necessitate higher levels of st

296 then tested the combination of HCD and EThcD fragmentation, which were employed in a product-dependen

297 Quantification of habitat fragmentation will help guide threat assessment and stra

298 ubule structure with a drastically increased fragmentation within bone marrow and a significantly red

299 act protein mass and sequence generated from fragmentation within the instrument.

300 Fragmentation within the second RNA recognition motif (R