ライフサイエンスコーパス: fragmented

1 mitochondria are thick (swollen) and short (fragmented).

2 cent genome assemblies remain incomplete and fragmented.

3 identified, decorin was found to be the most fragmented.

4 equence is a TNL or CNL, potentially full or fragmented.

5 this growing field, but efforts to-date are fragmented.

6 contact as hosts decline and habitats become fragmented.

7 ide contigs, which themselves are often very fragmented.

8 matrix Ca(2+) is increased and mitochondria fragmented.

9 dge about sequence functional sites is quite fragmented.

10 ural habitat has become both rare and highly fragmented.

11 on and subpopulations are significantly more fragmented.

12 emissions from their construction is highly fragmented.

13 hich little habitat remains and it is highly fragmented.

14 HPV16 binds to and enters host cells remains fragmented.

15 e understanding of these processes is rather fragmented.

16 , and in many cases they become increasingly fragmented.

17 , and the present state of the literature is fragmented.

18 ver, our knowledge of this process is rather fragmented.

19 enetic variants are commonly used but highly fragmented across many resources.

20 orpus of documentation of these resources is fragmented across the Web, with much redundancy, and has

21 in fava beans, where vacuoles are naturally fragmented after ABA-induced stomata closure.

22 anges of arctic megafauna became permanently fragmented after stable, interglacial climate engendered

23 ter, as metagenomic assemblies are typically fragmented and also leave a large fraction of reads unas

24 Genes often appear fragmented and are split into more genes during annotati

25 corridor was submerged, and populations were fragmented and consequently reduced to low Holocene leve

26 However, existing data sets are fragmented and difficult to analyze systematically.

27 s of HD patients: impaired sleep initiation, fragmented and diminished sleep, and nighttime hyperacti

28 Additionally, fragmented and distorted NMJs were evident at both the l

29 n populations living close to forest margins fragmented and disturbed by deforestation may be particu

30 oT25N mutant mitochondria also were severely fragmented and exhibited reduced kinesin and dynein moti

31 ria, national surveillance efforts are still fragmented and heterogeneous, and have substantial struc

32 However, these assemblies are mostly fragmented and inaccurate at the whole genome scale, lar

33 tivity, and show that it self-organizes from fragmented and incoherent states to connected and synchr

34 genomes, such as that of bread wheat, remain fragmented and incomplete.

35 s; and (4) private-well support programs are fragmented and lack sufficient resources.

36 as dominated by smallholders tend to be less fragmented and less degraded.

37 the past decade, but these genomes are often fragmented and missing complex repeat regions.

38 iterature on psychogenic amnesia is somewhat fragmented and offers little prognostic value for indivi

39 porting HIV programs were found to be highly fragmented and poorly integrated into national health sy

40 cted protein-coding genes, five of which are fragmented and presumably nonfunctional.

41 t genes) of full-length cDNAs are amplified, fragmented and short-read-sequenced.

42 Two major Golgi phenotypes were observed-fragmented and small Golgi.

43 as gradually attenuated as sleep became more fragmented and total sleep time was reduced relative to

44 Fragmented and unpredictable patterns of maternal care b

45 rategies for conservation in an increasingly fragmented and warmer world.

46 nowledge of the insulin signaling network is fragmented, and because of the complexity of this networ

47 esised that elastin becomes disorganised and fragmented, and decreases in amount with ageing, especia

48 vated levels of reactive oxygen species, are fragmented, and do not aggregate normally at axonal bran

49 Forests around the world are increasingly fragmented, and edge effects on forest microclimates hav

50 research on trophic rewilding is still rare, fragmented, and geographically biased, with the literatu

51 ane potential, mitochondria were extensively fragmented, and mitochondrial ultrastructure was grossly

52 lasma is almost exclusively free DNA, highly fragmented, and not virion associated.

53 icted protein-coding genes, of which six are fragmented, and seven paralogous gene families are prese

54 nvasive species and parasites of wildlife is fragmented, and the lack of international cooperation en

55 EV-enclosed mRNAs are mostly fragmented, and UTRs enriched; nevertheless, some full-l

56 about 8 times longer for the sensor based on fragmented antibodies.

57 caused REM sleep reduction and significantly fragmented any remaining REM sleep without affecting tot

58 change their form, acquiring an increasingly fragmented appearance consisting of numerous isolated re

59 Recovery rates of complete genomes from fragmented assemblies of single-cell templates significa

60 as the identification of duplicated genes in fragmented assemblies, although refinements are needed.

61 uenced using short reads, which yield highly fragmented assemblies.

62 fficult to assemble and often lead to highly fragmented assemblies.

63 hort reads technologies produce accurate but fragmented assemblies.

64 The Abl kinase sensor fragmented at 4.2 +/- 4.8 zmol muM(-1) s(-1) and the maj

65 Nucleosides fragmented at the N-glycosidic bond provide nucleobase a

66 ds to individual long DNA molecules that get fragmented at the same time (tagmentation).

67 are difficult to quantify given limited and fragmented availability of information.

68 romised neuritic outgrowth, and contorted or fragmented axons with swollen varicosities containing al

69 hypothesized to be as follows: (1) whole or fragmented bacterial cells which bioaccumulated metals a

70 ed capillaries with intercellular gaps and a fragmented basement membrane, facilitate delivery of mac

71 Instead, fragmented beta2m fibrils accumulate in lysosomes, alter

72 Incubation of cells with fragmented beta2m fibrils did not, however, cause cell d

73 pondingly, inhibiting the internalization of fragmented beta2m fibrils rescued cellular MTT reduction

74 tlantic Forest of Brazil are two of the most fragmented biodiversity hotspots.

75 of collagen fingerprinting to more than 2000 fragmented bones from the site of Denisova Cave, Russia,

76 plug containing the gradient is subsequently fragmented by a droplet generator.

77 ers of the Laurentian Great Lakes, which are fragmented by at least 6,692 dams and 232,068 road cross

78 ine reversed-phase liquid chromatography and fragmented by collision-induced dissociation (CID), foll

79 ring this period, New Zealand was repeatedly fragmented by glaciers into a series of refugia, with th

80 ian tree species whose populations have been fragmented by human activity and is protected wherever i

81 that these noncovalent complexes can also be fragmented by surface-induced dissociation (SID) followi

82 n is that in two dimensions the clusters are fragmented by the movements caused by rearranging the ce

83 Patients continued to experience fragmented care determined by diagnostic categories rath

84 access to a neuromuscular specialist or had fragmented care; 37.5% of 359 unplanned neuromuscular di

85 damage checkpoint to form ultrafine bridges, fragmented centromeres, and uneven chromosome segregatio

86 s and other products e.g. cholestadienes and fragmented cholesterol molecules.

87 ng from DNA repair and APOBEC editing of the fragmented chromatin bridge DNA.

88 egulation of Trex2, which was recruited into fragmented chromatin in keratinocytes that were undergoi

89 fail to recruit RecN to DSBs and accumulate fragmented chromosomes after exposure to MMC.

90 terials similar to reduced GO (rGO) that are fragmented compared to the starting material, and low mo

91 sult, existing assembly tools tend to output fragmented contigs or chimeric contigs, or have high mem

92 When forest is fragmented, cut, thinned, cleared or otherwise altered i

93 naling and insulin resistance is hampered by fragmented data, mainly obtained from different cell lin

94 The present study focuses on fragmented deglycosylated pyranose dehydrogenase (fdgPDH

95 privatisation combined with hospital-centred fragmented delivery were to prevail--population health o

96 le development, middle of the road, and more fragmented development), which each included six scenari

97 ies and social media outlets, resulting in a fragmented discourse.

98 umulation of damaged mitochondria, which are fragmented, display remodelled cristae and release cytoc

99 The species' fragmented distribution may reduce gene flow, which coul

100 e selection pressures across their naturally fragmented distributions in southern Melanesia.

101 Fragmented DNA is recognized as nutrient source for micr

102 ssage through the G1/S transition, contained fragmented DNA, and underwent apoptosis.

103 actor power, the global surgery community is fragmented, does not have unifying leadership, and is mi

104 white spruce genome sequence remains highly fragmented, dozens of scaffolds encompassing more than o

105 Here, we show that a fragmented draft assembly is sufficient to perform mappi

106 Regeneration of fragmented Drosophila imaginal discs occurs in an epimor

107 habitats leading to the pervasive view that fragmented ecological communities collapse from the top

108 paper, we ask what proportion of forest in a fragmented ecosystem is impacted by altered microclimate

109 In addition to showing reduced and fragmented elastic fibers, the histopathological hallmar

110 operties of the aortic wall characterized by fragmented elastic lamellae, whereas mice homozygous for

111 have many features to suggest they represent fragmented ER, and some are physically separated from th

112 be activated by endogenous alarmins such as fragmented extracellular matrix proteins found in degene

113 Networks fragmented faster and global efficiency decreased faster

114 placed by a provincial and biogeographically fragmented fauna by Middle Triassic times (Anisian, appr

115 fibrils is dependent on fibril length, with fragmented fibrils being more efficiently internalized b

116 tory infected coral systematically exhibited fragmented fluorescent pigments adjacent to the disease

117 The area of fragmented fluorescent pigments in diseased coral extend

118 ial carbon sink but is also the most heavily fragmented forest biome in the world.

119 derstand orangutan movement in disturbed and fragmented forests of Malaysian Borneo.

120 ransposable element transcripts maintained a fragmented form with a relatively low transcript level a

121 These findings indicate that full-length and fragmented forms of netrin-1, found in multiple sclerosi

122 llenges remain, in particular in coping with fragmented genes or genes evolving at different rates af

123 ting the inherent challenge in maintaining a fragmented genome.

124 This technology detects low copy number and fragmented genomes extracted from formalin-fixed paraffi

125 tly been documented using plasmid, viral, or fragmented genomic DNA; dPCR performance with more compl

126 c investigations, and assist the assembly of fragmented genomic sequences.

127 carry information about the structure of the fragmented glycans.

128 derived from all three individuals showed a fragmented Golgi that could be rescued by expression of

129 spread disruption of trophic interactions in fragmented habitats and describes variation among studie

130 roles of livestock and wildlife as hosts in fragmented habitats, limiting the development of meaning

131 apted to substantial ecological pressures in fragmented habitats.

132 In adsorption experiments fragmented HDPE bags c.

133 ients remain challenging; limited resources, fragmented health care, and high levels of injection dru

134 rce, ageing and turnover of village doctors, fragmented health information technology systems, a pauc

135 In regions with scarce resources, fragile or fragmented health systems, cancer contributes to the cyc

136 epends on implementation within the complex, fragmented health-care system.

137 etermining the speed of population spread in fragmented/heterogeneous landscapes is therefore of utmo

138 "Type 3" multilaminar fragmented hyperreflectivity (found in 22 scans of 11 ey

139 went extensive fusion, but then subsequently fragmented in a pS473-KAP1-dependent manner.

140 We show that MTOCs are fragmented in a three-step process.

141 The nad5 gene is fragmented in five exons, belonging to three distinct tr

142 ind that the ProtoNK cluster was extensively fragmented in some lineages, showing that NK clustering

143 o the protein were isolated by quadrupol and fragmented in the ICR cell by the ECD method.

144 expanded coverage by building onto a highly fragmented, inefficient, and costly health system.

145 resence of integrated surface structure from fragmented input.

146 dered at many High Arctic sites by short and fragmented instrumental climate records.

147 ds with complex transverse geometry are thus fragmented into a periodic train of rods held stationary

148 , with the highly conserved Atpalpha subunit fragmented into four separate pieces.

149 If these species are further fragmented into genetically isolated subpopulations, the

150 Cladophorales green algae, which is entirely fragmented into hairpin chromosomes.

151 Usually, their results are incomplete and fragmented into hundreds of contigs.

152 their role as cell protectants, can again be fragmented into MDA.

153 Ca.　Hodgkinia genome from M. tredecim has fragmented into multiple new chromosomes or genomes, wit

154 pulation of C. monodonta will become further fragmented into smaller populations, each of which will

155 l surface remains roadless, but this area is fragmented into ~600,000 patches, more than half of whic

156 over, we also demonstrate that activation of fragmented IP3R1 can result in a distinct functional out

157 Scattered, presumed fragmented keratocyte nuclei, were observed at 1 and 3 m

158 ns, and many draft and reference genomes are fragmented, lacking skewed GC and repetitive intergenic

159 g-lived palm Oenocarpus bataua in a recently fragmented landscape (<2 generations) in northwest Ecuad

160 ith good colonization capacity in the highly fragmented landscape before the extinction of the popula

161 ion declines steeper in higher quality, less-fragmented landscapes (an inverse buffer effect) than in

162 lected a wheat-rice double-cropped area from fragmented landscapes along the rural-urban complex (Jia

163 ble habitats will be colonized under current fragmented landscapes and realistic migration rates.

164 We suggest that avian communities in fragmented landscapes are more robust to climate change

165 frequencies in SW Finland resemble those in fragmented landscapes as opposed to continuous landscape

166 Metapopulation persistence in fragmented landscapes depends on habitat patches that ca

167 ls that include finer-grained assessments in fragmented landscapes rather than using averaged coarse-

168 Fragmented landscapes that have more complex 3D vegetati

169 ty can mediate host-pathogen interactions in fragmented landscapes, and provides evidence that connec

170 e applied to model more complex food webs in fragmented landscapes, broadening the scope of existing

171 species that are not well adapted to live in fragmented landscapes, the conventional SAR underestimat

172 t forest loss is most detrimental in already fragmented landscapes.

173 able landscapes and 200% farther in the most fragmented landscapes.

174 pattern and fitness changes expected within fragmented landscapes.

175 ized as key factors affecting communities in fragmented landscapes.

176 persistence of the metapopulation in random fragmented landscapes.

177 eful indicator of genetic change in recently fragmented landscapes.

178 lations to adapt to novel climates in highly fragmented landscapes.

179 ese declines is challenging in heterogeneous fragmented landscapes.

180 0 mm were analyzed for voltage and abnormal (fragmented/late potential) electrogram characteristics.

181 -dG adduct that can yield the imidazole ring-fragmented lesion, N(5)-NM-substituted formamidopyrimidi

182 With thermal activation, the fragmented ligands transform catalytically into closed-r

183 mbination of a flat free-energy landscape, a fragmented local structure, and the narrow temperature w

184 ebsites and apps and avoid further growth of fragmented, low-quality care.

185 he pyrochlore iridate Ho2Ir2O7, leading to a fragmented magnetization.

186 by the perceptions of a relatively small and fragmented market that may discourage major pharmaceutic

187 fraction (known to contain the cell wall and fragmented membranes) in the presence of SRHA than in it

188 Neurons from Bif-1-deficient mice contained fragmented mitochondria and Bif-1 knockdown in wild-type

189 ed mitochondrial fission and accumulation of fragmented mitochondria and decreased elongated mitochon

190 analysis revealed a significant increase in fragmented mitochondria in the podocytes of wild-type di

191 ed in elongated mitochondria, in contrast to fragmented mitochondria observed upon staurosporine and

192 ggested that loss of fusion capacity targets fragmented mitochondria to the pre-autophagic pool and u

193 On actin disassembly, fragmented mitochondria undergo rapid fusion, leading to

194 ckdown in wild-type neurons also resulted in fragmented mitochondria which were more depolarized, sug

195 e salt glycochenodeoxycholate (GCDC) rapidly fragmented mitochondria, both in primary mouse hepatocyt

196 acetyltransferase (ChAT) enzyme expression, fragmented mitochondria, glial cell activation, muscle a

197 of OPA1 protein with normal mRNA expression, fragmented mitochondria, impaired bioenergetics, increas

198 In fibroblasts, however, CPT resulted in fragmented mitochondria.

199 N2 downregulation and the presence of highly fragmented mitochondria.

200 hromosomes, the mechanisms of inheritance in fragmented mitochondrial genomes remain mysterious.

201 Livers from Mfn1LKO mice displayed a highly fragmented mitochondrial network.

202 highly connected versus those with a highly fragmented mitochondrial structure, suggesting the feasi

203 at were responsive to C12, DKOR MEF): nuclei fragmented; mitochondrial membrane potential (Deltapsimi

204 re authentic standards or databases of known fragmented molecules.

205 mmobilized peptide nucleic acid probe, while fragmented mRNA targets from three different full length

206 er microplastics, the cubic ones mostly, are fragmented much faster than the parallelepipeds.

207 1-F2 pre-assembled into amyloid oligomers or fragmented nanoscaled fibrils was highly cytotoxic.

208 suming, costly and low-yield and it produces fragmented nanosheets with submicrometre lateral dimensi

209 y the exonuclease activity of MRE11, and the fragmented nascent DNA accumulates in the cytosol, initi

210 However, the degraded and fragmented nature of aDNA has posed technical challenges

211 The fragmented nature of metagenomic protein predictions adv

212 ucture often affect phenotypes, although the fragmented nature of most contemporary assemblies obscur

213 The heavily fragmented nature of the Brazilian Atlantic forest means

214 ted new challenges due to the incomplete and fragmented nature of the data.

215 The fragmented nature of the influenza A genome allows the e

216 have been missed or truncated because of the fragmented nature of the reference metagenome.

217 Due to its complexity and fragmented nature, however, working with pathway data is

218 ernomastoid and tibialis anterior, displayed fragmented neuromuscular synapses and a mixture of modes

219 euromuscular transmission at the most highly fragmented NMJs in the diaphragms of old (26-28 months)

220 e showed that RBS was associated with highly fragmented nucleoli and defects in both ribosome biogene

221 which natural populations live increasingly fragmented, often leading to local extinctions.

222 The Bowman membrane was fragmented or absent.

223 e systems are in place, but most of them are fragmented or poorly coordinated.

224 The assembly of the highly fragmented Oxytricha macronuclear genome is the first co

225 trypanosomes and nematodes leaves a somehow fragmented picture of the possible biological significan

226 nd geographical barriers have created a more fragmented picture.

227 CHW programs for HIV in Southern Africa are fragmented, poorly integrated, and lack long-term suppor

228 Demographic links among fragmented populations are commonly studied as source-si

229 ffected by inbreeding, with implications for fragmented populations facing mate limitation and stress

230 Anthropogenically fragmented populations showed lower genetic diversity an

231 nanocomposites by producing what is called "fragmented products" (FP).

232 urther size fractionation to isolate "sieved fragmented products" (SFP) that are representative for i

233 e.g., humidity, light) to produce "weathered fragmented products" (WFP) or can be subjected to a furt

234 Odds ratio was highest for fragmented QRS and TWA (odds ratios: 6.73 and 4.66, 95%

235 mice show evidence of sinus bradycardia and fragmented QRS complex, supporting the critical role of

236 ch block, signal-averaged electrocardiogram, fragmented QRS, QRS-T angle, and T-wave alternans) were

237 agmented quantum wells, and a combination of fragmented quantum wells with quantum dots.

238 ng gain media including InGaN quantum wells, fragmented quantum wells, and a combination of fragmente

239 rs and found that the compounds could impact fragmented rAAV2 transduction to an even greater extent

240 teniposide coadministration greatly enhanced fragmented rAAV8 transduction at 48 h and 8 days.

241 he N4, N5, N6, and N8 NA subtypes using gene-fragmented random mutagenesis.

242 as that students learn are often isolated or fragmented rather than integrated and coherent.

243 Using a fragmented reference sequence led to a dramatic increase

244 financial and human-resource limitations and fragmented referral systems that prevent continuity of c

245 We conclude that highly fragmented regions are likely to undergo less pronounced

246 tion and function, diverse stakeholders, and fragmented regulatory authority.

247 BTIC mitochondria were fragmented relative to non-BTIC tumor cell mitochondria,

248 emanding and the assembled contigs are often fragmented, resulting in the identification of protein s

249 confidence interval: 0.71, 0.96), and a more fragmented rhythm was associated with a higher mortality

250 cD2-anchored dynein stretches the MTOCs into fragmented ribbons along the nuclear envelope.

251 ry are especially strong in catchments where fragmented rocks are more exposed to weathering, and the

252 ebilitating human diseases, possess multiply fragmented rRNAs that together are analogous to 28S rRNA

253 a model that classifies extracted ORFs from fragmented sequences.

254 n general, resource consumption increased in fragmented settings for habitat generalist consumers but

255 In humans and Drosophila, C3POs cleave the fragmented siRNA passenger strands and facilitate the ac

256 Fragmented sleep is a common and troubling symptom in ag

257 unrelated families corroborates late and/or fragmented sleep patterns in carriers, suggesting that i

258 ted sleep, which was best characterized by a fragmented sleep profile.

259 active intermediate nucleus neurons had less fragmented sleep, after adjusting for age and sex, and t

260 We also explore the contribution of fragmented sleep, and the disruption of sleep structure,

261 The consequences include more fragmented sleep, prolonged wake at night, shallower sle

262 id (Abeta) accumulation leads to reduced and fragmented sleep, while chronic sleep deprivation increa

263 halamic ventrolateral preoptic nucleus cause fragmented sleep.

264 Highly fragmented social networks with cohesive subgroups are a

265 t the pathogen remained isolated in the same fragmented southern refugia as its host plant during the

266 nd, but declined to extinction in the nearby fragmented southwestern (SW) Finnish archipelago in the

267 self-motion cues to form a global map across fragmented spaces.

268 which 85% is in intact molecules and 15% is fragmented species.

269 g population connectivity in conservation of fragmented species.

270 dead) we distinguished between complete and fragmented specimens.

271 g increased frequencies of mispositioned and fragmented spindles.

272 different nature of the excitations in this fragmented state opens the way to tunable field-induced

273 ds to the formation of oxidised derivatives, fragmented sterols and oligomers.

274 y carbon and biodiversity cobenefits in such fragmented systems.

275 ults of hybridization studies conducted with fragmented target DNA (ftDNA) of V. cholerae using elect

276 t, HCD with higher NCE values preferentially fragmented the peptide backbone and, thus, provided info

277 hat HCD with lower NCE values preferentially fragmented the sugar chains attached to the peptides to

278 In our study, a kinase lead compound was fragmented, the hinge-binding motif extracted as a core

279 nomic coverage in the tree of life is highly fragmented, there is an urgent need for a reference-free

280 PLN-KO fragmented these cell-wide SCWs into mini-waves and Ca(2

281 precursors pass Q1 at the same time and are fragmented, thus impairing the library search algorithms

282 RF number and position on genic regions with fragmented total and polysomal mRNA illuminated numerous

283 olutions of hollow-shell gamma-Fe(3)O(4) NPs fragmented upon refluxing shows no evidence of organic m

284 Here, lipid ions are fragmented using electron impact excitation of ions from

285 with existing biochemical applications were fragmented using incubation with Pronase E and/or formic

286 ies in which all peptides are systematically fragmented using wide mass-isolation windows ('multiplex

287 The fragmented vacuolar phenotype of sac mutants could be mi

288 ubstrate (AES) as characterized by prolonged fragmented ventricular potentials.

289 jects at study and then, at test, identified fragmented versions of studied (old) and nonstudied (new

290 apparent reduction in background noise, and fragmented vessels in the images before averaging became

291 n of this approach is the circularization of fragmented viral RNAs, which are then redundantly encode

292 sequencing revealed the presence of several fragmented virulence genes that probably are nonfunction

293 ession in the DR, while the consolidation of fragmented wakefulness correlated with the number of nor

294 ut the brain causes excessive sleepiness and fragmented wakefulness during the nocturnal active phase

295 Peptides were fragmented with collision-induced dissociation using iso

296 AChR clusters became fragmented with diminished junctional folds and synaptic

297 that the field of sustainability is largely fragmented, with a range of academic disciplines and pro

298 ies with therapeutic expertise are typically fragmented, with major elements missing in thousands of

299 However, these assemblies are highly fragmented, with many gaps, ambiguities, and errors, imp

300 obtained from spores extracted from minute, fragmented, yet exceptionally anatomically preserved fos