ライフサイエンスコーパス: frameshift mutation

1 ivating mutations (nonsense, splice-site, or frameshift mutations).

2 while the second patient had a c.592_593dup frameshift mutation.

3 lls from schizophrenia patients with a DISC1 frameshift mutation.

4 2 expression was disrupted by an insertional/frameshift mutation.

5 (a-3, a-4, and a-5) each containing a unique frameshift mutation.

6 tors carried an 8-bp mutS deletion causing a frameshift mutation.

7 his construct undergoes continual subsequent frameshift mutation.

8 s appear to result from gene duplication and frameshift mutation.

9 ) (CD22DeltaE12) and results in a truncating frameshift mutation.

10 lineage, rpmGC is a pseudogene containing a frameshift mutation.

11 ch carries the protein-truncating c.6174delT frameshift mutation.

12 Four patients shared exon 10 V452WfsX38 frameshift mutation.

13 he domain 1 voltage sensor and introducing a frameshift mutation.

14 he dG(1,8) site, creating a complex for "-2" frameshift mutation.

15 lls required TGFBR2-even the form encoding a frameshift mutation.

16 lines, consisting of nonsense, missense and frameshift mutations.

17 n, minimizing generation of more deleterious frameshift mutations.

18 re expression of polypeptides in the face of frameshift mutations.

19 itutions (M(1)dG --> A and M(1)dG --> T) and frameshift mutations.

20 n strand breaks and potentially deletion and frameshift mutations.

21 pair (MMR) can lead to base substitution and frameshift mutations.

22 s (mostly M(1)dG to dT and M(1)dG to dA) and frameshift mutations.

23 otein C (gC), and gD, respectively, harbored frameshift mutations.

24 mechanism in LQT2 patients with nonsense or frameshift mutations.

25 sversion base substitutions and certain (-1) frameshift mutations.

26 er tracts during replication and can lead to frameshift mutations.

27 ically in the avoidance of transversions and frameshift mutations.

28 jority being either nonsense substitution or frameshift mutations.

29 which is specifically affected by one of the frameshift mutations.

30 tures present in subjects with DVL1 and DVL3 frameshift mutations.

31 ds to large numbers of base substitution and frameshift mutations.

32 rrelated positively with the total number of frameshift mutations.

33 Forty-three mutations, including 8 frameshift mutations, 10 nonsense mutations, 4 splice si

34 ilaggrin S100 domain, whereas two additional frameshift mutations, 1249insG and 7945delA, occur in th

35 t with HS-RDEB, who was homozygous for a new frameshift mutation, 345insG, in exon 3 of COL7A1.

36 Of these, 21 (2 frameshift mutations, 4 nonsense mutations, 4 splice sit

37 tients with CD who were heterozygous for the frameshift mutation (6% of CD cases analyzed) had reduce

38 aza and 4 aza-8-fluoro derivatives increased frameshift mutations about 22- and 4-fold, respectively.

39 e been described to date, with the c.649dupC frameshift mutation accounting for the majority of cases

40 The p.F513SfsX113 frameshift mutation adds 113 amino acids to the C termin

41 and characterization of a novel heterozygous frameshift mutation affecting the carboxy-terminus (439f

42 re, we observed that a known illness-related frameshift mutation after amino acid 807 causes the C re

43 patients with GATA2 deletions and one with a frameshift mutation also have primary lymphedema.

44 Glis3 observed in NDH1 patients results in a frameshift mutation and a C-terminal truncated Glis3.

45 ctivates a cryptic splice site, leading to a frameshift mutation and a premature stop codon that rend

46 omponent TrkA was originally thought to be a frameshift mutation and not to encode a functional prote

47 meshift mutation, one had exon 4 Q130SfsX130 frameshift mutation and one had exon 10 Q468X stop codon

48 ein regulatory complex member, resulted in a frameshift mutation and PCD.

49 emonstrated a thymine insertion leading to a frameshift mutation and premature truncation of catalase

50 duce exon skipping; the other mutations were frameshift mutations and a deletion.

51 , we identified three independent homozygous frameshift mutations and a homozygous deletion of two ex

52 We identified two homozygous frameshift mutations and a homozygous nonsense mutation

53 rprisingly mistranslated because of numerous frameshift mutations and large indels.

54 ad RNA-seq output to reliably identify small frameshift mutations and missense mutations in highly ex

55 We detected two unique frameshift mutations and one duplication in three patien

56 gKaKs can automatically detect and eliminate frameshift mutations and premature stop codons to comput

57 y changes: either a straight morphology from frameshift mutations and single nucleotide polymorphisms

58 tal age on base substitutions, we found that frameshift mutations and transposition events increased

59 A in which functional loss from nonsense and frameshift mutations and/or targeted deletions is observ

60 d resulted in two premature stop codons, one frameshift mutation, and one cysteine to glycine amino a

61 tations, 10 indels, 14 nonsense mutations, 9 frameshift mutations, and 5 splice-site mutations.

62 ases were characterized by both missense and frameshift mutations, and enzymatic activity of BAP1 mis

63 These included four missense mutations, two frameshift mutations, and one tRNA homopolymer expansion

64 Frameshift mutations are particularly deleterious to pro

65 t the majority of reported LQT2 nonsense and frameshift mutations are potential targets of NMD.

66 set of lacZ strains revealed that genetic -1 frameshift mutations are strongly elevated in Clp-defect

67 the rates of hybridization-induced point and frameshift mutations as well as homologous recombination

68 We found that base substitutions outnumber frameshift mutations, as seen in other experimental syst

69 he mutations include missense, nonsense, and frameshift mutations, as well as splice-site and deletio

70 tary motor neuropathy of a dominant-negative frameshift mutation at the C-terminus of choline transpo

71 rtion of a transposable element as well as a frameshift mutation, both of which are completely absent

72 the anticodon loop are known to suppress +1 frameshift mutations, but in no case has the molecular m

73 ility of XMC, we identified the novel CHRDL1 frameshift mutation c.807_808delTC [p.H270Wfs*22] presum

74 -2A>G), whereas the other bears a homozygous frameshift mutation (c.1328_1329insT [p.Tyr444fs*3]) in

75 rphogenetic Protein-4) gene and identified a frameshift mutation (c.226del2, p.S76fs104X) that segreg

76 patient was homozygous for an ablative APOE frameshift mutation (c.291del, p.E97fs).

77 A described frameshift mutation (c.33_34insC) occurred with the next

78 her 32-year-old cousin were homozygous for a frameshift mutation (c.45_46del AG, p.T15Tfsx27) in exon

79 family from New Zealand with a heterozygous frameshift mutation (c.465dupA) in exon 7.

80 ity for two mutations in the PSAT1 gene--one frameshift mutation (c.delG107) and one missense mutatio

81 ng whole-exome sequencing, we identified two frameshift mutations (c.981_993del [p.Gln327Hisfs( *)102

82 ations were detected, but a homozygous RAPSN frameshift mutation, c.1177-1178delAA, was identified in

83 date gene sequencing identified a homozygous frameshift mutation, c.139_140delAG, in the transmembran

84 osed with CVID and identified a heterozygous frameshift mutation, c.2564delA (p.Lys855Serfs( *)7), in

85 ffected children and identified a homozygous frameshift mutation, c.571dupA (p.Ile191Asnfs( *)6), in

86 a large Israeli family revealed a homozygous frameshift mutation, c.947delA (p.Lys316Serfs( *)90), an

87 We identified a novel ESR2 frameshift mutation, c.948delT, which segregated with hi

88 We tested the hypothesis that a deletion and frameshift mutation (C563fsX673) in the CEL VNTR causes

89 A heterozygous frameshift mutation causing a 12-amino acid extension to

90 furazone, and suppressed the frequency of -1 frameshift mutations characteristic of Pol IV, while los

91 UV-induced mutagenesis, we focused on the +1 frameshift mutations detected by reversion of the lys2de

92 wo reports showed that 3 different net -1 bp frameshift mutations early in DSPP's repeat domain cause

93 Model mRNAs carrying frameshift mutations exhibited a YoeB-mediated cleavage

94 -linked families identified three additional frameshift mutations, for a total of four truncating all

95 l cancer patients with peptides derived from frameshift mutations found in their tumors.

96 a patient with SRNS with a homozygous ADCK4 frameshift mutation had partial remission following CoQ1

97 deletion and one-third exhibit homopolymeric frameshift mutations (HFMs).

98 ts deficient for UV-induced reversion of the frameshift mutation his4-38.

99 We report the first intragenic deletion and frameshift mutations identified in RAD21 in two patients

100 ed resequencing study, we identified a CXCR2 frameshift mutation in a pedigree with congenital neutro

101 dy shows that whole-genome duplication and a frameshift mutation in ACE2 are sufficient to generate a

102 A novel homozygous frameshift mutation in ADCK3 (p.Ser616Leufs*114), was id

103 g was supported by the discovery of a NOTCH1 frameshift mutation in an unrelated family with similar

104 P4S1 (NM_007077.3: c.124C>T, p.Arg42( *)), a frameshift mutation in AP4B1 (NM_006594.2: c.487_488insT

105 repair protein, Msh2 in the correction of a frameshift mutation in both yeast and mammalian cells.

106 he consequences of a familial PAH-associated frameshift mutation in CAV1, P158PfsX22, on caveolae ass

107 We identified a frameshift mutation in caveolin-1 (CAV1), which encodes

108 p1 or pgp2 or a reduction in curvature due a frameshift mutation in cjj81176_1105, a putative peptido

109 le-genome sequencing identified a homozygous frameshift mutation in CORO1A disrupting the last 2 C-te

110 identified a spontaneous mouse mutant with a frameshift mutation in Crx (CrxRip).

111 he discovery cohort, we associated CD with a frameshift mutation in CSF2RB (P = 8.52 x 10(-4)); the f

112 on in DUOX2 that impaired its function and a frameshift mutation in CSF2RB that was associated with C

113 We identified a frameshift mutation in CSF2RB that was replicated in an

114 Jewish individuals, we associated CD with a frameshift mutation in CSF2RB.

115 ere found to have at least one allele with a frameshift mutation in DOK7 exon 7, suggesting that loss

116 direct DNA sequencing, we have identified a frameshift mutation in exon 1 of KRT5 in the proband fro

117 Tapasin loss is caused by a germ-line frameshift mutation in exon 3 (TAPBP(684delA)) along wit

118 exome sequencing, we identified a homozygous frameshift mutation in EXPH5 in three siblings with inhe

119 ne receptor M3 (CHRM3) (1q41-q44) homozygous frameshift mutation in familial congenital bladder malfo

120 g AD came from flaky tail mice, which have a frameshift mutation in Flg and also carry an unknown gen

121 We report an ultra-rare, heterozygous frameshift mutation in FZD5 (p.Ala219Glufs*49) that was

122 ine the effect of microsatellite length upon frameshift mutation in gene-specific sequence contexts,

123 Restoration of pathogenicity by repair of a frameshift mutation in GPCMV gene GP129 using this appro

124 ient patient lack XLF due to an inactivating frameshift mutation in its gene, and that reintroduction

125 bouriffe (ebo/ebo) harbors a homozygous 2-bp frameshift mutation in Lrrc8a that truncates the 15 term

126 lele frequency of 0.1% and found a recessive frameshift mutation in MYL4 that causes early-onset atri

127 In the fifth family, we identified a frameshift mutation in NNT, a nuclear-encoded mitochondr

128 and functional evidence demonstrating that a frameshift mutation in one paralog, Helianthus annuus FT

129 An MNV replicon with a frameshift mutation in open reading frame 2 (ORF2) that

130 A frameshift mutation in pgp1 of our laboratory isolate of

131 n another family, we discovered a homozygous frameshift mutation in PSPH, the gene encoding phosphose

132 ygome/exome analysis identified a homozygous frameshift mutation in RSPRY1 with resulting nonsense-me

133 ous cell carcinomas identified a case with a frameshift mutation in SCCRO that putatively codes for a

134 ete PAI-1 deficiency because of a homozygous frameshift mutation in SERPINE-1.

135 that stochastically becomes functional by a frameshift mutation in single cells.

136 tified a homozygous 1-bp deletion inducing a frameshift mutation in STAG3 on chromosome 7.

137 exome sequencing revealed a novel homozygous frameshift mutation in the basic helix-loop-helix transc

138 f the COL13A1 c.1171delG (p.Leu392Sfs( *)71) frameshift mutation in the C2C12 cell line reduced acety

139 lpha1PV is a dominant negative mutant with a frameshift mutation in the carboxyl-terminal 14 amino ac

140 In humans, a frameshift mutation in the coding sequence of the DLX3 g

141 s rat is severely osteopetrotic because of a frameshift mutation in the colony-stimulating factor-1 (

142 er disrupted the start codon or introduced a frameshift mutation in the early coding region, ensuring

143 Genome sequencing identified a frameshift mutation in the eccCa1 gene.

144 uria, we identified a homozygous deleterious frameshift mutation in the gene CUBN, which encodes cubu

145 osome 1p36-p35 and identified a heterozygous frameshift mutation in the gene encoding atrial natriure

146 A novel homozygous frameshift mutation in the gene encoding for LAT was ide

147 ere ketoacidosis and identified a homozygous frameshift mutation in the gene encoding monocarboxylate

148 equencing identified a heterozygous germline frameshift mutation in the gene encoding nitrogen permea

149 tified a spontaneous genomic duplication and frameshift mutation in the guanine exchange factor dedic

150 p A streptococcus carriage strain contains a frameshift mutation in the hasA gene resulting in loss o

151 A frameshift mutation in the human TWIK-related spinal cor

152 ess using oligonucleotides that correct a -1 frameshift mutation in the LYS2 gene of Saccharomyces ce

153 differences that might be found, including a frameshift mutation in the mycocerosic acid synthase gen

154 varian failure (POF) identified a homozygous frameshift mutation in the STAG3 gene leading to a prema

155 Unexpectedly, these data also revealed a frameshift mutation in the UL13 kinase in our strain F i

156 Positional cloning revealed an early frameshift mutation in tmie, the zebrafish ortholog of t

157 ailable from one patient showed a homozygous frameshift mutation in tripeptidyl peptidase II (TPP2) a

158 ed and a C. trachomatis isolate containing a frameshift mutation in trpR was isolated.

159 ons was rescued by a secondary, compensatory frameshift mutation in U(L)41.

160 l cancers from two independent cohorts where frameshift mutations in 19 genes were analyzed and CD3(+

161 heterozygous ACTB deletions and nonsense and frameshift mutations in 33 individuals with developmenta

162 d either homozygous or compound heterozygous frameshift mutations in 4 of 33 unrelated cases of LQTS

163 The two evolved cell lines showed different frameshift mutations in a stretch of eight adenosines in

164 de novo heterozygous missense, nonsense, and frameshift mutations in BCL11A, encoding a transcription

165 onsense-mediated mRNA decay in patients with frameshift mutations in BRCA1 and BRCA2.

166 strong selection against indels that caused frameshift mutations in coding regions.

167 Genes containing frameshift mutations in colon cancer cell line have been

168 k established between CD8(+) TIL density and frameshift mutations in colorectal cancer.

169 iseases, with higher frequencies of nonsense/frameshift mutations in DLBCL compared with FL.

170 Frameshift mutations in exon 12 of the nucleophosmin gen

171 After <SPTX, patients with nonsense or frameshift mutations in exons 2, 9, and 10 had a signifi

172 Animals carrying 3 distinct frameshift mutations in fga were raised and bred to prod

173 us exonic deletions, nonsense mutations, and frameshift mutations in five further unrelated families

174 lysis of patients revealed several different frameshift mutations in intron 6 or exon 7 of KRT10.

175 rare, autosomal dominant disorder caused by frameshift mutations in KRT10 or KRT1 and characterized

176 Expression of LCA-associated dominant CRX frameshift mutations in mouse retina mimicked the CrxRip

177 failure and identified compound heterozygous frameshift mutations in NSMCE2.

178 We identified two missense and one frameshift mutations in one Pakistani and two Turkish fa

179 enotype resulted from nonsense, missense, or frameshift mutations in prfA Five strains carried hly mu

180 re is thought to reflect the accumulation of frameshift mutations in sequences that are repeated with

181 Here we show that missense, nonsense and frameshift mutations in SLC6A5, encoding the presynaptic

182 Frameshift mutations in the calreticulin (CALR) gene are

183 Recently, frameshift mutations in the caveolar structural protein

184 re, we report the identification of frequent frameshift mutations in the coding mononucleotide repeat

185 ymptomatic carriers, we identified recurrent frameshift mutations in the cohesin-associated factor PD

186 ditional 1515 CD cases and 7052 controls for frameshift mutations in the colony-stimulating factor 2-

187 is study implicate KRT1 and KRT10 C-terminal frameshift mutations in the high frequency of revertant

188 uncating frameshift, missense, or homozygous frameshift mutations in the last exon.

189 Compared with the exclusive activating frameshift mutations in the proline, glutamic acid, seri

190 oth type 2P (CMT2P) has been associated with frameshift mutations in the RING domain of LRSAM1 (an E3

191 ereditary spastic paraplegia (HSP) caused by frameshift mutations in the SPG20 gene that results in a

192 some MSI-H CRC cells despite the presence of frameshift mutations in the TGFBR2 gene because the muta

193 ome (>77,400 for 5- to 20-nt HP tracts), and frameshift mutations in these regions are likely to disr

194 en probands had newly identified nonsense or frameshift mutations in this gene.

195 ilies, we identified heterozygous C-terminal frameshift mutations in TREX1, which encodes a 3'-5' exo

196 y microsatellite instability (MSI-H) develop frameshift mutations in tumor suppressors as part of the

197 ty as well as for the majority of UV-induced frameshift mutations in yeast.

198 ndary somatic loss-of-function (nonsense and frameshift) mutations in SAMD9 rescued the growth-restri

199 igation of an apparent correlation between a frameshifting mutation in the canonical first exon of NO

200 utation (one missense, one nonsense, and one frameshift mutation) in GPR126.

201 In addition, four frameshift mutations including three novel mutations of

202 Interestingly, the percentage of overall frameshift mutations increased from 71 (37 degrees C) to

203 state carcinoma cell line homozygous for the frameshift mutation induced altered regulation of severa

204 bineering strategy to introduce simultaneous frameshift mutations into the flanking Hoxa9, Hoxa10 and

205 Selection against frameshift mutation is a main constraint on tandem repea

206 In family 1, a frameshift mutation L330fsdel17ins9 (c.987 1003del17ins9

207 function as a transcription factor, or were frameshift mutations leading to TCF12 truncated for this

208 This frameshift mutation leads to a caveolin-1 protein that c

209 This frameshift mutation leads to caveolin-1 protein that con

210 omatic NF1 loss was different in each tumor (frameshift mutation, loss of heterozygosity, and methyla

211 These results provide insight into how -1 frameshift mutations might be generated for the PdG addu

212 indicated that loss of expression was due to frameshift mutations, mostly by addition or deletion of

213 ibuting to A-->T and A-->C transversions and frameshift mutations observed in cells following treatme

214 lls from four members of a family in which a frameshift mutation of disrupted in schizophrenia 1 (DIS

215 A novel frameshift mutation of four-and-a-half LIM domain 1 gene

216 We observed frameshift mutations of CDKN1B in 14 of 180 SI-NETs, and

217 mutated sequences as those of patients with frameshift mutations of the THRA gene.

218 rtaken to characterize the effects of a TPP1 frameshift mutation on the retina in Dachshunds.

219 One patient had exon 1 C31LfsX34 frameshift mutation, one had exon 4 Q130SfsX130 frameshi

220 We have identified one frameshift mutation, one splice-site mutation, and two m

221 Polkappa has the highest potential to create frameshift mutations opposite the abasic site.

222 false-positive calls of nonsense mutations, frameshift mutations, or genomic rearrangements for any

223 nonhomologous end joining repair, leading to frameshift mutations, or homology-directed repair using

224 moter methylation (P = .04), p53 nonsense or frameshift mutations (P = .01), and a gene expression si

225 deletion in exon 6 at codon 260 results in a frameshift mutation, p.Asp260fs, altering residues 260-2

226 s included a complete deletion of RTN2 and a frameshift mutation predicted to produce a highly trunca

227 The mutations included three frameshift mutations, predicted to encode truncated prot

228 We discovered multiple exon deletions, frameshift mutations, premature stop codons, and transcr

229 on of translation occurred downstream of the frameshift mutation, probably at the BRCA1-Met-297 codon

230 We used a minigene system to study two frameshift mutations, R1032Gfs 25 and D1037Rfs 82.

231 xonucleases ExoI and ExoVII display elevated frameshift mutation rates but not base substitution muta

232 Significant changes in frameshift mutation rates were also observed in some hyb

233 feU gene of E. coli K-12 is cryptic due to a frameshift mutation - repair of the single-base-pair del

234 owed a clear phenotype-genotype correlation: Frameshift mutations resulted in severe phenotypes with

235 Frameshift mutations resulting in a truncated Riz1 incap

236 sent in T-ALL are predominantly heterozygous frameshift mutations resulting in truncation of the C-te

237 enerate single-base deletions (also known as frameshift mutations) resulting from DNA template-strand

238 ce isolate, where the gene is disrupted by a frameshift mutation, resulting in a pseudogene.

239 premature stop codon introduced by the CHADL frameshift mutation results in nonsense-mediated decay o

240 This frameshift mutation results in the loss of the stop codo

241 The frameshift mutation results in the production of a trunc

242 4.0 x 10(-12), odds ratio (OR) = 16.7) and a frameshift mutation, rs532464664 (p.Val330Glyfs*106), in

243 tive to valine-resistance assay that detects frameshift mutations showed that mutagenesis is elevated

244 MSI tumors had increased frameshift mutations, showed genetic evidence of immunoe

245 This new frameshift mutation shows that overlapping DSPP mutation

246 Null alleles with ACC2 nonsense mutations, frameshift mutations, small deletions, genomic rearrange

247 n PTPN22 was identified, including two novel frameshift mutations (ss538819444 and rs371865329) and t

248 cluded the possibility of a gain-of-function frameshift mutation such as those found in loricrin or c

249 athway is known to increase the frequency of frameshift mutations suggesting competition between thes

250 A novel homozygous frameshift mutation (T base deletion at nucleotide posit

251 ble mutant that induces even higher rates of frameshift mutation than does the wild-type hAAG; the Y1

252 hotobacterial cqsA genes harbour a conserved frameshift mutation that abolishes CAI-1 production.

253 three SMO missense mutations, and one PTCH1 frameshift mutation that are novel and have not been doc

254 al, TERT, revealed a missense mutation and a frameshift mutation that cosegregated with pulmonary dis

255 First, OG1X contains a frameshift mutation that inactivates the etaR response r

256 orchidism, and absent puberty), a homozygous frameshift mutation that is predicted to disrupt the 3 C

257 The duplication predicted a frameshift mutation that led to a premature stop codon a

258 ant AdEasyE1Delta2347, which carries the Hr6 frameshift mutation that prevents production of the E1B

259 it pays off handsomely, identifying a single frameshift mutation that segregates with the disease.

260 ong necrotizing fasciitis cases has a unique frameshift mutation that truncates MtsR, a transcription

261 One tumor harbored a frameshift mutation that was germline in origin, thus re

262 ve evolution in haplotypes segregating for a frameshift mutation that was previously thought to indic

263 ontaining either an internal stop codon or a frameshift mutation that would render the protein produc

264 ding to Nal(r) and for base substitution and frameshift mutations that occur in the lacZ gene.

265 tations that fall on interfaces and nonsense/frameshift mutations that result in truncated negative r

266 6%) and consisted exclusively of nonsense or frameshift mutations that truncated the coding region at

267 All the variants are either nonsense or frameshift mutations that, in representative cases, resu

268 s as a potential mechanism leading to an N-1 frameshift mutation, the nick left after the removal of

269 ne repair, leading to substitution and short frameshift mutations, they are both a source of genome d

270 The introduction of frameshift mutations to exon 11 resulted in nonsense-med

271 We demonstrate that nonsense and frameshift mutations trigger NMD, providing further evid

272 One frameshift mutation (truncation at amino acid 1171) pred

273 a homozygous p.D18fs*13 TRDN-encoded triadin frameshift mutation was discovered in a 10-year-old fema

274 An independent de novo frameshift mutation was identified in a child with idiop

275 A homozygous frameshift mutation was identified in LRAT in 4 patients

276 Consequently, a frameshift mutation was identified in mucA, a key regula

277 A frameshift mutation was introduced that replaced the las

278 sing even further when at least one of these frameshift mutations was present in all tumor cells.

279 essing an NOD2 gene with the Crohn's disease frameshift mutation were only slightly resistant to TNBS

280 that result in amino acid substitutions and frameshift mutations were also observed, though in a rat

281 s repeat domain caused DD, whereas 6 more 3' frameshift mutations were associated with DGI.

282 Frameshift mutations were associated with earlier age of

283 In total, six distinct frameshift mutations were found in eight subjects, and a

284 ere sequenced, and no missense, nonsense, or frameshift mutations were found.

285 Novel frameshift mutations were identified in 5 patients.

286 Frameshift mutations were introduced into the gag gene s

287 TIL densities increased when frameshift mutations were present within the ASTE1, HNF1

288 d the VEEV capsid, with a previously defined frameshift mutation, were found to have no detectable ef

289 es); two siblings shared the same homozygous frameshift mutation, whereas one individual with sporadi

290 escribe a new humanized FUS-ALS mouse with a frameshift mutation, which fulfils both criteria: the FU

291 FOS-induced mutation was characterized by +1 frameshift mutations, which increased from 0% in control

292 These included nonsense and frameshift mutations, which most likely lead to haploins

293 ne confirmed abnormal splicing, leading to a frameshift mutation with early termination.

294 of NCF4 showed compound heterozygosity for a frameshift mutation with premature stop codon and a miss

295 h the G3 site is an established hot spot for frameshift mutation with the model arylamine derivative

296 utations were detected in 47 cases (10%): 46 frameshift mutations with insertion/deletion of one to 2

297 Seven independent missense or frameshift mutations within mshA were identified and cha

298 ensity to promote C-->A transversions and -1 frameshift mutations within poly(dGMP) and poly(dAMP) ru

299 NA deletions, rearrangements, or nonsense or frameshift mutations within the APOA1 gene resulting in

300 The following 2 novel frameshift mutations within ZEB1 were identified: c.2617