ライフサイエンスコーパス: fraught

1 pic surveillance is invasive, expensive, and fraught by issues of sampling bias and the subjective as

2 elopment of prognostic models in WM has been fraught by limited follow-up in current studies.

3 explanatory depth available from politically fraught fields like evolution.

4 MPA in more complex systems are likely to be fraught with a high degree of uncertainty.

5 ue and perioperative management RAAA remains fraught with a high rate of death and complications.

6 ed over the helical scaffold such that it is fraught with a huge steric strain to undergo required bo

7 y to cross-couple secondary alkyl centers is fraught with a number of problems, including difficult r

8 th the most efficient regimens available, is fraught with a substantial proportion of failures to reo

9 ral percutaneous transluminal angioplasty is fraught with a substantial risk of restenosis and reinte

10 ng reprogramming methodologies, however, are fraught with caveats, including a heavy reliance on vira

11 scovery, filled with therapeutic promise yet fraught with caveats.

12 e management of anophthalmia in the child is fraught with challenges and nuances, the principal aim i

13 Learning their structure and intricacies is fraught with challenges, and often side-stepped in favou

14 study showed that UHC is a complex process, fraught with challenges, many possible pathways, and var

15 ts gains for MSM remains markedly uneven and fraught with challenges.

16 tionships after termination of treatment are fraught with complexities and are the subject of ongoing

17 n the mainstay of care for IOI, their use is fraught with complications and side-effects, suggesting

18 tro evaluation of colistin susceptibility is fraught with complications, due in part to the inherent

19 ing following third-degree burn injuries are fraught with complications, often resulting in long-term

20 rified the nature of PTLD, the literature is fraught with conflicting experience and outcomes with PT

21 or membrane proteins, the extrapolations are fraught with considerable uncertainty as the denaturants

22 n channel complexes is challenging and often fraught with contradictory results.

23 Misrepair is also fraught with danger, especially inappropriate end-joinin

24 get genes, particularly in cancer, have been fraught with dead ends and context-specific functions.

25 owever, all elements of informed consent are fraught with difficulties due to the unique nature of th

26 tive in releasing the drug rapidly, they are fraught with difficulties inherent in processing particu

27 However, use of the Tet-On system has been fraught with difficulties, including high background exp

28 this pre-biomineralization fossil record is fraught with difficulties, leading to controversial and

29 ng RPM might seem straightforward, but it is fraught with difficulties.

30 es of the webs and the links between them is fraught with difficulties.

31 ction in experimentally derived sequences is fraught with difficulties.

32 tempts at targeting these pathways have been fraught with difficulties.

33 ke therapeutic manipulation of these systems fraught with difficulties.

34 Replication of DNA is fraught with difficulty and chromosomes contain many les

35 argue that this use of natural images is so fraught with difficulty that it is not useful.

36 se individuals in primary prevention is also fraught with difficulty.

37 tice or clinical research, however, has been fraught with difficulty.

38 duction is extremely important, but has been fraught with difficulty.

39 Predicting the future is fraught with difficulty; nonetheless, it is apparent tha

40 irect links across phenotypic hierarchies is fraught with difficulty; we identify issues complicating

41 l practice but may be difficult to obtain or fraught with error.

42 phisms in this duplicated region potentially fraught with error.

43 Although testing of mAbs has been fraught with failure and confusing results, the experien

44 few species, countries, and ecoregions, and fraught with generalisations from weak inference.

45 raft dysfunction and immune stimulation, and fraught with high rates of intolerance.

46 rategies for reconstructing bony defects are fraught with inadequacies.

47 the randomized trials used for analysis are fraught with inconsistencies, including the availability

48 However, the literature is fraught with inconsistent accounts as to whether various

49 Yet, such sophisticated analyses are fraught with interpretive difficulties.

50 Staples are fraught with limitations including high-localized tissue

51 odification may be helpful, but even this is fraught with limited efficacy and potential complication

52 s been colon; however, most series have been fraught with major complications and conduit loss.

53 heless, any inter-trial comparison is always fraught with major difficulties, and an indirect compari

54 The history of ALS drug discovery is fraught with many stops and starts.

55 h studies of trauma system effectiveness are fraught with methodologic difficulties, several types of

56 idence base is limited, and most studies are fraught with methodologic limitations, including cross-s

57 en studies, because quantification of AEA is fraught with methodological difficulties.

58 and neighboring phosphoglyceryl complex were fraught with obstacles.

59 liciting reliable responses from newborns is fraught with operational difficulties, and studies with

60 n adaptive way of coping with an environment fraught with pathogens.

61 entify, however, making their interpretation fraught with pitfalls.

62 ic characters means that using these data is fraught with potential difficulties, leading to errors i

63 nosis of some infectious diseases and yet is fraught with potential pitfalls.

64 st infection, and current drug therapies are fraught with problems, predominantly because of the prot

65 Clearly, both are fraught with problems.

66 ergency airway management in children can be fraught with problems.

67 the genes for psychotic illnesses have been fraught with problems.

68 Travel into outer space is fraught with risk of exposure to energetic heavy ion rad

69 tration of such myeloablative transplants is fraught with risks, some of which are related to the int

70 esent methods to measure telomere length are fraught with shortcomings that limit their use.

71 road to integration and acceptance has been fraught with skepticism and technical hurdles.

72 c category guiding translational research is fraught with so many problems that the validity of resea

73 dard therapy for Wegener's granulomatosis is fraught with substantial toxicity and not always effecti

74 of HCV replication in extrahepatic sites is fraught with technical challenges, and in vitro systems

75 mary tumors, however, the analysis of LOH is fraught with technical problems that have limited its re

76 n in patients with atopic dermatitis (AD) is fraught with the inability to precisely assess the age o

77 The study of virulence is fraught with the paradox that virulence, despite being a

78 still a largely manual task and, therefore, fraught with the potential for error.

79 many effective choices, but as a class it is fraught with the risk of serious peptic ulcer disease an

80 C expression in hepatocellular carcinoma are fraught with the theoretical possibility of injuring adj

81 l go functionally extinct in the future, are fraught with uncertainty.

82 current treatment methods for KS and PEL are fraught with unwanted side effects and low efficiency, t