ライフサイエンスコーパス: free fraction

1 nt of the arterial input function and plasma free fraction.

2 ontent (1061-2988mgGAE/kg) was determined in free fractions.

3 so found in both membrane-bound and membrane-free fractions.

4 duced 'dinoflagellate', 'bacteria' and 'cell-free' fractions.

5 (11)C-UCB-J exhibited high free fraction (0.46 +/- 0.02) and metabolized at a moder

6 Complete remission (tumor-free fraction, 100%) was found for tumor doses of 12.4 a

7 ume of distribution (0.23 +/- 0.14 L/kg) and free fraction (17.5% +/- 5.0%) were increased in critica

8 ll potency, low clearance in mouse, and high free fraction, 2 demonstrated significant efficacy in mo

9 rs, and toxicity risks related to the higher free fraction and lower clearance of bupivacaine in neon

10 ir coimmunoprecipitation in the cytoskeleton-free fraction and neuronal soma.

11 In the protein-free fraction and water-soluble proteins (WSP), all five

12 ific binding in the brain, (b) higher plasma free fraction, and (c) faster plasma clearance and brain

13 ciently high solubility, high plasma protein free fraction, and favorable pharmacokinetics to suggest

14 and SDS were able to increase the furosemide free fraction available for oral absorption.

15 migrates with polysomes rather than ribosome-free fractions, but this is lost under stress.

16 lasma clearance was 29 +/- 1 L/h, and plasma free fraction (f(1)) was 5% +/- 1%.

17 cantly higher levels of total plasma parent, free fraction (f(1)), and free plasma parent in women th

18 The plasma free fraction (f(1)), total parent, and clearance demons

19 Plasma clearance (in liters per hour) and free fraction (f1) of the parent tracer were measured.

20 cans with arterial input function and plasma free fraction (fP) measurements.

21 PBR28 distribution volume (VT) corrected for free fraction (fP) was measured in patients with TLE and

22 ion of conditions for removal of thyroxine's free fraction from samples without significant interfere

23 ne-containing fraction T and plasma membrane-free fractions H and L.

24 On the basis of the measurable free fraction, high affinity and selectivity, adequate b

25 On the basis of its measurable and stable free fraction, high affinity and selectivity, good blood

26 as attributed to the poor reliability of the free fraction (ICC = 0.35) and free parent (ICC = 0.68).

27 vitro potency and selectivity profile, high free fraction in human plasma, good oral bioavailability

28 In 6 scans, arterial input functions and free fraction in plasma (fp) were measured.

29 of distribution in region of interest, fP is free fraction in plasma).

30 alysis (HD) is severely limited by their low free fraction in plasma.

31 cators of binding kinetics, and unmeasurable free fraction in plasma.

32 nds with lower cLogP values and an increased free fraction in plasma.

33 P(ND) equals the product of BP(F) and f(nd) [free fraction in the nondisplaceable compartment]), the

34 igand binding by the increase of radioligand free fractions in plasma.

35 The median DTG free-fraction in SP was 48% of the total drug.

36 oskeleton-bound, vs. a soluble, cytoskeleton-free fraction, inducing their coimmunoprecipitation in t

37 The free fraction is 59% +/- 3%.

38 r activity (P. aeruginosa MIC90 = 2 mug/mL), free fraction levels (>20% free), and hydrolytic stabili

39 bolite-corrected arterial input function and free-fraction measurement to estimate 5-HT1A binding pot

40 venient and accurate method of measuring the free fraction of (99m)Tc-MDP by comparing it with the gl

41 al volumes of distribution corrected for the free fraction of 2FA in plasma (V(T)/f(P)) in 10 nonsmok

42 developed for measuring the noncomplexed or free fraction of a hormone in serum based on the combine

43 Aqueous pollen extracts, the protein-free fraction of Amb-APE, and the pollen-contained subst

44 o increased the microsomal stability and the free fraction of compounds as evidenced through a pairwi

45 es of events that lead to an increase in the free fraction of his serum bilirubin.

46 The free fraction of MPA and the free MPA AUC were markedly

47 h was evaluated by using it to determine the free fraction of phenytoin in serum or samples containin

48 In the final UFIDA method, the free fraction of phenytoin was extracted in approximatel

49 was also used to measure simultaneously the free fraction of testosterone and its equilibrium consta

50 SA microcolumns were utilized to measure the free fraction of testosterone in hormone/protein mixture

51 , peripheral blood lymphocytes, and the cell-free fraction of the blood plasma.

52 ssue that increased with the increase of the free fraction of the radioligand in plasma.

53 bumin using both a direct measurement of the free fraction of the small molecule as well as using a c

54 te concentration-dependently neutralized the free fraction of ticagrelor and reversed its antiplatele

55 a high degree of protein binding reduces the free fraction of toxins and decreases their diffusion ac

56 system was tested by using it to measure the free fractions of (R)- or (S)-warfarin in samples with k

57 Additionally, the free fractions of FL (fu) in all the plasma samples were

58 ow that Gbetagamma co-segregates with dynein-free fractions of Tctex-1.

59 Repeat-free fractions of the closely related mammalian genomes

60 Free fractions of the HOCs were determined as C(water(eq

61 binding to plasma proteins that elevated the free fractions of the radioligand in plasma.

62 Brine-releasable (BR-) and free fractions of Volatile Sulfur Compounds were determi

63 was developed for measuring the nonbound (or free) fraction of drugs by using millisecond-scale extra

64 a technique for analyzing myelin and myelin-free fractions separately.

65 ween 3 and 4 were likely to have significant free fraction, so we designed compounds in this range to

66 lasma, purified LDL, or the apolipoprotein B-free fraction through a scaled-down, experimental dextra

67 The average plasma free fraction was 0.2%; thus, the tracer's in vivo disso

68 The plasma free fraction was 8.9% +/- 1.6% for (11)C-DASB and was n

69 orrelation; however, when compounds with <5% free fraction were excluded, a more predictable correlat

70 orrected arterial input functions and plasma free-fraction were acquired to improve quantification.

71 of this series have improved solubility and free fraction when compared to compounds in the previous

72 cin D, L5 and L11 accumulate in the ribosome-free fraction where they bind to Mdm2.

73 osone were the major products in the protein-free fraction, whereas in the WSP, 3-deoxythreosone was