ライフサイエンスコーパス: free radical scavenger

1 s was improved by in vivo treatment with the free radical scavenger.

2 monstrating that cleavage is suppressed by a free radical scavenger.

3 suggesting that genipin may act as a direct free radical scavenger.

4 (OHSC), as well as its potential as a direct free radical scavenger.

5 sodium sulfate-inflamed mice, treated with a free radical scavenger.

6 Both effects are attenuated by the use of a free radical scavenger.

7 n the reaction occurred in the presence of a free radical scavenger.

8 cell death, suggesting that AIF serves as a free radical scavenger.

9 ffects of central neurotoxins by acting as a free radical scavenger.

10 damaged proteins, presumably by acting as a free radical scavenger.

11 ned to ascertain whether clonidine acts as a free radical scavenger.

12 was inhibited by catalase, heme poisons, and free radical scavengers.

13 he hypoxia-induced response are inhibited by free radical scavengers.

14 ibited by l-Trp, the heme ligand cyanide, or free radical scavengers.

15 e or redox active metal ions or inhibited by free radical scavengers.

16 ly 10 microM for 6-keto-PGF1alpha) and other free radical scavengers.

17 ll wine samples were found to be less potent free radical scavengers.

18 superior neuroprotective actions to those of free radical scavengers.

19 remodeling of the extracellular matrix, and free radical scavengers.

20 tion of 4-OHEN-mediated enzyme inhibition by free radical scavengers.

21 reased by hydrogen peroxide and inhibited by free radical scavengers.

22 ent probe concentration, and the presence of free-radical scavengers.

23 The free radical scavenger 2-mercaptoethanol completely supp

24 olic activity were inhibited by the nitrogen free radical scavenger 2-phenyl-4,4,5,5,-tetramethylimid

25 In addition, treatment with a free-radical scavenger, 4-hydroxytetramethylpiperidine-1

26 ing UV irradiation with one of the following free-radical scavengers: 40 mM D-mannitol, 40 mM imidazo

27 lic moiety of etoposide acts as an effective free radical scavenger, accounting for its antioxidant a

28 tors may significantly enhance intracellular free radical scavenger activity.

29 Recent studies have suggested that free radical scavenger administration reduces the rate o

30 ory product of the pineal gland, is a direct free radical scavenger, an indirect antioxidant, as well

31 Thus, GSH, commonly viewed as a universal free radical scavenger and major intracellular antioxida

32 eratrol (RES), and quercetin (QUE) are known free radical scavengers and have shown cardioprotective

33 h activation of caspase-3 and was reduced by free radical scavengers and Z-Val-Ala-Asp fluoromethylke

34 L), we measured the effectiveness of tempol (free radical scavenger) and creatine (enhances cellular

35 eus, is shown here to function directly as a free radical scavenger, and adducts formed as a result o

36 As a free radical scavenger, and cofactor, ascorbate (ASC) is

37 e, however, is also a potent antioxidant and free radical scavenger, and numerous studies have shown

38 ssue damage and the effects of antioxidants, free radical scavengers, and overexpression of superoxid

39 n shown to decrease inflammation, upregulate free radical scavengers, and prevent the formation of re

40 otiter plate assay for the quantification of free radical scavengers (antioxidants) in food samples i

41 These data suggest that free radical scavengers are effective in all cell types

42 native form of superoxide dismutase (SOD), a free radical scavenger, are limited because of its short

43 s are discussed with reference to the use of free radical scavengers as potential anti-aging agents.

44 This is reversed by co-administration of the free radical scavenger ascorbate.

45 es calcium influx into neurones or acts as a free radical scavenger at concentrations below 100 micro

46 chloride (7 micromol/L), each of which is a free radical scavenger, blocked protection, indicating t

47 yses that have been employed to evaluate the free radical scavenger capacity of carotenoid molecules

48 Furthermore, targeting mitochondria with free radical scavengers conferred superior protection ag

49 ted with PS conjugated to the oxygen-derived free radical scavenger DFO.

50 reaks were unaffected by the presence of the free radical scavenger dimethyl sulfoxide (DMSO) or by f

51 The free radical scavenger DMSO or the gap junction inhibito

52 The addition of the free radical scavenger DMSO produces an insignificant ef

53 Furthermore, addition of free radical scavengers (e.g., DMSO, glycerol, and catio

54 In this study, we tested the efficacy of the free radical scavenger edaravone in three cellular model

55 ulata polar extracts were the most efficient free-radical scavengers, Fe(2+) chelators and inhibitors

56 lts support the concept of developing oxygen free radical scavengers for both AD and PD and further s

57 nfluenced by the presence of the less potent free radical scavengers gallic and caffeic acids.

58 n-2-yl)piperazine-1-sulfonamide possessing a free radical scavenger group (FRS), chelating groups (CH

59 Free radical scavengers have failed to improve patient o

60 Procyanidins (PCs) are effective free radical scavengers, however, their antioxidant abil

61 electron transport chain as well as a potent free radical scavenger in lipid and mitochondrial membra

62 have analyzed the localization of superoxide free radical scavengers in different striatal neuron typ

63 were synthesized and found to be equipotent free radical scavengers in solution as assessed by EPR a

64 Ascorbic acid is a potent free-radical scavenger in plasma, and also regulates int

65 ace an additional pressure on ascorbate as a free-radical scavenger in this population.

66 f oxothiazolidine-4-carboxylic acid (OTZ), a free radical scavenger, in treating acute respiratory di

67 rget kinase protein kinase-B is blocked with free radical scavengers, indicating a role for reactive

68 Neuroprotective strategies, including free radical scavengers, ion channel modulators, and ant

69 Administration of the free radical scavenger L-N-acetylcysteine blocked MS-275

70 argely attenuated by coadministration of the free radical scavenger L-N-acetylcysteine.

71 ppa B (NF-kappa B) activation; moreover, the free radical scavenger L-N-acetylcyteine (LNAC) blocked

72 ore, vascular expression and activity of the free radical scavengers manganese and extracellular supe

73 Melatonin and AFMK, as potent free radical scavengers, may assist plants in coping wit

74 Dexrazoxane, a free-radical scavenger, may protect the heart from doxor

75 Furthermore, the free radical scavenger, melatonin (2 mM), prevented the

76 o the reported neuroprotective action of the free radical scavenger, melatonin, against cerebral isch

77 y was designed to evaluate the impact of the free radical scavenger metallothionein on high-fat diet-

78 the impact of glutathione depletion and the free radical scavenger, metallothionein (MT), on cardiac

79 Catechin, a free radical scavenger, minimized the increase in free r

80 The free radical scavenger Mn(III)tetrakis(4-benzoic acid)po

81 EDTA and the free radical scavengers Mn(2+) and Trolox, a vitamin E a

82 3-phenylpropylamino)-benzoate (NPPB), or the free radical scavenger N-acetyl cysteine (NAC) each prov

83 dismutase or the application of the hydroxyl-free radical scavenger N-acetyl cysteine (NAC) to the Si

84 The free radical scavenger N-acetyl cysteine blocked LAQ824-

85 In addition, the free radical scavenger N-acetyl-L-cysteine attenuated RO

86 he effect of serum on lipolysis, whereas the free radical scavenger N-acetyl-l-cysteine completely in

87 ad NOS inhibitor N(G)-methyl-l-arginine, the free radical scavenger N-acetyl-l-cysteine, or the NOS s

88 rogated by pretreatment of PC cells with the free radical scavenger N-acetyl-L-cysteine.

89 as diminished, along with cell death, by the free radical scavenger N-acetylcysteine (NAC).

90 We further demonstrated that the free radical scavenger N-acetylcysteine blocked arachido

91 determine whether delayed treatment with the free radical scavenger N-tert-butyl-a-phenylnitrone (PBN

92 ed by PD184352/UCN-01 was not blocked by the free-radical scavenger N-acetyl-L-cysteine.

93 Thiol-containing free-radical scavengers N-acetyl cysteine, dimethyl- and

94 es, 2.4 atm); systemic administration of the free radical scavenger, N-acetylcysteine (NAC 150 mg kg(

95 F-induced permeability as treatment with the free radical scavenger, N-acetylcysteine, inhibited this

96 estigated the protective nature of the known free radical scavenger, N-tert-butyl-alpha-phenylnitrone

97 and activation of JNK were attenuated by the free-radical scavenger NAC, suggesting that oxidative da

98 r (DEVD.CHO, 8 microgram intrastriatally), a free radical scavenger (OPC-14117; 600 mg/kg, orally) an

99 e accomplished in control experiments when a free radical scavenger or a melatonin analog were substi

100 ol-adsorbed-superoxide dismutase (PEG-SOD; a free-radical scavenger), or PEG-SOD alone.

101 mol/L N-2-mercaptopropionyl glycine (MPG), a free radical scavenger, or by 200 micromol/L 5-hydroxyde

102 itor chelerythrine (10(-7) M) or the O(-)(2) free radical scavengers polyethylene glycol superoxide d

103 ithin this muscle and that pretreatment with free radical scavengers prevents lipid peroxidation and

104 re, we found that supplementing vitamin E, a free radical scavenger, reduces the oxidative state in P

105 changes can be prevented by treatment with a free radical scavenger, resulting in improved motility.

106 N-Acetylcysteine (NAC) is a potent free radical scavenger shown in animal models to attenua

107 s significantly decreased by addition of the free radical scavengers, SOD, CAT or GPX.

108 The utility of using free radical scavengers such as CeO(2) nanoparticles to

109 ntially all of these events were reversed by free radical scavengers such as the manganese superoxide

110 D inhibitor is encouraging and suggests that free radical scavengers, such as vitamin E, may have a p

111 The free radical scavenger superoxide dismutase attenuated r

112 l xanthine oxidase (XO), with or without the free radical scavengers superoxide dismutase (SOD; 100 U

113 Exposure of the carotid sinus to the free-radical scavengers superoxide dismutase (SOD) and c

114 r transformed lymphoid cells, is reversed by free radical scavengers, synergizes with the antileukemi

115 g an activation of glutathione and ascorbate free radical scavenger systems.

116 In contrast, the free radical scavengers TEMPO and TEMPONE and the anti-o

117 Treatment of TRPM2+/+ mice with the free radical scavenger Tempol or the PARP1 inhibitor 3-a

118 The free radical scavenger Tempol, but not other classes of

119 ced by silencing BCL10 or by exposure to the free radical scavenger Tempol.

120 The free radical scavenger, tempol, is known to have cardiop

121 The most potent free radical scavengers that we tested for in the wine s

122 Two free radical scavengers, the salen-manganese complex EUK

123 confocal microscopy, that was blocked by the free radical scavenger tiron but not by a caspase-2 inhi

124 Both the free radical scavengers Trolox and Mn2+, and the metal c

125 monitored with and without coincubation of a free-radical scavenger (trolox).

126 As a free radical scavenger, uric acid has been postulated to

127 The free radical scavenger Vitamin E significantly attenuate

128 ) exchange blocker (amiloride), or an oxygen free radical scavenger (vitamin E).

129 no protective effect, and 4-hydroxy TEMPO, a free radical scavenger, was not protective.

130 limited sensitivity to all other classes of free radical scavengers we have tested.

131 Nerve growth factor and free radical scavengers were inactive in this system.

132 Melatonin, a pineal hormone and a potent free radical scavenger with neuroprotective actions, has