ライフサイエンスコーパス: fresh-frozen

1 hin 24 to 36 hours of death, and immediately fresh frozen.

2 , stained with hematoxylin and eosin, and/or fresh frozen.

3 Fresh frozen and formalin-fixed, paraffin-embedded sampl

4 serial mouse brain and liver sections, both fresh frozen and formalin-fixed.

5 We validate our method on cell-line data, fresh frozen and paraffin-embedded tumour tissue samples

6 dant potential of irradiated (0.5 and 1 kGy) fresh, frozen and dried samples were determined by chrom

7 f hematopoietic subsets in RNA mixtures from fresh, frozen and fixed tissues, including solid tumors,

8 hod can be applied to all kinds of products; fresh, frozen and processed, including those undergoing

9 on of DNA copy number alterations from small fresh-frozen and FFPE clinical tumor specimens, although

10 lon were recovered in comparable yields from fresh-frozen and FFPE preserved tissues of rodents treat

11 Results on fresh-frozen and ground whole bone of several mammalian

12 er injection, and their hearts were excised, fresh frozen, and sectioned for histology and immunohist

13 iable prostate cancer cell lines and various fresh-frozen benign and malignant tissue specimens.

14 All five anti-PSMA mAbs reacted with fresh-frozen benign prostate secretory-acinar epithelium

15 g microarray gene expression data of matched fresh frozen biopsies as a gold standard.

16 adverse events associated with placement of fresh-frozen bone allografts (FFBAs) during alveolar rid

17 ows for the detection of two mRNA species in fresh frozen brain tissue sections.

18 Immunoblot analysis of fresh frozen brain tissues revealed that tau was present

19 mbers of apoptotic cells as well as in other fresh frozen brains.

20 Four fresh-frozen cadaver hip joints from two male donors, ag

21 omatic genetic variations were identified in fresh frozen clinical specimens by Illumina RNA-sequenci

22 and endothelial cells) protein expression in fresh-frozen corneal tissue suggests that Fas ligand exp

23 man donors, aged stillborn to 85 years, were fresh frozen, cryostat sectioned, and prepared for indir

24 onors (age range, 6 months to 67 years) were fresh frozen, cryostat sectioned, and prepared for indir

25 ral heads from five embalmed donors and five fresh-frozen donors were compared using Raman microspect

26 We compared fresh frozen tissue, fresh frozen endoscopic brushings, and the Cytosponge de

27 olytica/E. dispar, and C. parvum in fresh or fresh-frozen fecal specimens.

28 h for employing LCM of epithelial cells from fresh frozen fetal tissue that enables quantitative anal

29 Moreover, fresh/frozen fish consumption, longer birth intervals, a

30 s applied to examine protein localization in fresh frozen human cornea cells.

31 detected in each major corneal cell type in fresh frozen human cornea.

32 we assessed the expression of SEPT9 in 7287 fresh frozen human tissue samples and 292 human cell lin

33 helial, keratocyte, and endothelial cells in fresh-frozen human cornea.

34 Protein expression in fresh-frozen human corneal sections was studied with imm

35 The specimens studied included fresh-frozen lesional tissues obtained from 16 patients

36 a component of a tissue lysate derived from fresh frozen lung tumor.

37 erns obtained directly from small amounts of fresh frozen lung-tumour tissue could be used to accurat

38 mune markers were assessed in parallel using fresh-frozen lung tissue from sibling rats of the same c

39 in 8-microm tissue sections obtained from a fresh frozen lymph node tumor infiltrated by metastatic

40 s for fresh plant tissue, formalin-fixed and fresh frozen mammalian tissue, fixed cells and biofluids

41 be used to interrogate DNA from cell lines, fresh frozen material and FFPE samples to assess copy nu

42 multiple sclerosis (n = 108, 34 males) with fresh frozen material available for genetic analyses and

43 iferation signature-using gene expression in fresh frozen material.

44 hival samples and the insufficient access to fresh-frozen material are partly the cause of the delaye

45 al antibodies were retrieved by selection on fresh-frozen MCB tissue sections.

46 iant cell lines (UISO, MCC13, and MCC26) and fresh frozen MCC tumors.

47 s were derived from the IMS investigation of fresh frozen mouse liver and rabbit adrenal gland tissue

48 In this study, we analyzed 199 fresh-frozen OPSCC specimens for HPV DNA, viral load, RN

49 al contrast echocardiography and then either fresh frozen or embedded in paraffin were determined by

50 ylation of DNA extracted from microdissected fresh frozen or formalin-fixed paraffin-embedded tissue

51 ng to search for somatic mosaic mutations in fresh, frozen, or fixed archival tissue from six affecte

52 nome analysis of DNA methylation profiles in fresh-frozen oropharyngeal squamous cell carcinoma (OPSC

53 es and/or p16 immunohistochemistry assays on fresh frozen paraffin-embedded tissue blocks.

54 cid compounds that have implications for the fresh-frozen pea industry.

55 platelets (0.86 U vs. 0.24 U, p = 0.001) and fresh frozen plasma (0.68 U vs. 0.24 U, p = 0.015).

56 ut also the proportion of patients requiring fresh frozen plasma (21.1% vs. 48.3%, P = 0.025).

57 s of platelets (10.0 versus 6.6 U, P<0.012), fresh frozen plasma (4.8 versus 3.1 U, P<0.03), and cryo

58 ns for use of other blood components such as fresh frozen plasma (FFP) and platelet transfusions are

59 sought to define the overall utilization of fresh frozen plasma (FFP) and platelets and the impact o

60 tments utilized in clinical practice include fresh frozen plasma (FFP) and prothrombin complex concen

61 ) and is used to justify preprocedure use of fresh frozen plasma (FFP) and/or platelets (PLT).

62 re in the critically ill, data on the use of fresh frozen plasma (FFP) are limited.

63 duct, human polyclonal antibody, obtained as fresh frozen plasma (FFP) from a HPS survivor.

64 from Iraq supporting early aggressive use of fresh frozen plasma (FFP) in a 1:1 ratio to packed red b

65 plasma volume was removed and replaced with fresh frozen plasma (FFP) or with 50% FFP and 50% albumi

66 Because the administration of fresh frozen plasma (FFP) prevents gastrointestinal blee

67 The practice of a high transfusion ratio of fresh frozen plasma (FFP) to red blood cells (RBCs) has

68 We assessed the safety and efficacy of fresh frozen plasma (FFP) versus prothrombin complex con

69 amounts of packed red blood cells (RBCs) and fresh frozen plasma (FFP) were recorded during hospital

70 ion of packed red blood cells (p = .442) and fresh frozen plasma (p = .063) were not different betwee

71 ess was developed to inactivate pathogens in fresh frozen plasma (PCT-FFP).

72 95% confidence interval [CI], 0.57 to 0.99), fresh frozen plasma (RR, 0.37; 95% CI, 0.21 to 0.64), an

73 8 U blood products (red blood cells [RBCs] + fresh frozen plasma [FFP] + platelets) had a median (int

74 ents who received a total of 46,101 units of fresh frozen plasma and 6,251 units of apheresis platele

75 The relative risk for transfusion of fresh frozen plasma and all infections was 2.99 (2.28-3.

76 ransfusion of high plasma volume components, fresh frozen plasma and apheresis platelets, from potent

77 analysis to evaluate the association between fresh frozen plasma and infectious complication, control

78 gnificant dose-response relationship between fresh frozen plasma and infectious complications (p = .0

79 The association between fresh frozen plasma and infectious complications remaine

80 ine concentrations, the amount of platelets, fresh frozen plasma and packed erythrocytes used, and th

81 nd anemia were corrected with transfusion of fresh frozen plasma and packed red blood cells.

82 or the continued unbridled administration of fresh frozen plasma and platelets without objective evid

83 ave shown to reduce bleeding, transfusion of fresh frozen plasma and platelets, and possibly mortalit

84 ns to platelets is the highest compared with fresh frozen plasma and red blood cells.

85 association was found between transfusion of fresh frozen plasma and ventilator-associated pneumonia

86 C1 inhibitor concentrates and fresh frozen plasma are available for acute intervention

87 Tranexamic acid or virally inactivated fresh frozen plasma can be used for long-term prophylaxi

88 The value of fresh frozen plasma components, both standard and steril

89 otal of 380 non-trauma patients who received fresh frozen plasma from 2004 to 2005 were compared with

90 ciation between infection and transfusion of fresh frozen plasma in patients who did not receive conc

91 Transfusion of fresh frozen plasma is associated with an increased risk

92 cation of these patients is critical so that fresh frozen plasma may be avoided.

93 o >1.5) or clinical (transfusion >2 units of fresh frozen plasma or >1 pack of platelets in 6 hours)

94 red blood cells, platelet concentrates, and fresh frozen plasma over the routine storage time.

95 The mean packed red blood cells to fresh frozen plasma ratio changed from 2.6:1 during the

96 Higher fresh frozen plasma ratios (> 1:2) were not associated w

97 ction without prior PVE demonstrated a lower fresh frozen plasma requirement (P = 0.01), a lower peak

98 ence of reactions to platelets compared with fresh frozen plasma suggests that a platelet-related fac

99 with an odds ratio of infection per unit of fresh frozen plasma transfused equal to 1.039 (1.013-1.0

100 -test allowed comparison of average units of fresh frozen plasma transfused to patients with and with

101 rative packed red cells (r=0.28, P=.049) and fresh frozen plasma transfusions (r=0.42, P=.004), highe

102 of platelet units (4.3 vs. 1.7, p =.05) and fresh frozen plasma units (1.1 vs. 0.6, p =.08) also was

103 tests) and the transfusion (blood units and fresh frozen plasma units) during the operative period w

104 id infusion volume (6.1-3.2 L) and increased fresh frozen plasma use (3.2-10.1 U) (both P < .05) in t

105 unoglobulin (4 cases), interferon (3 cases), fresh frozen plasma with WNV IgG (2 cases), and ribaviri

106 ood products (red blood cells, platelets, or fresh frozen plasma) administered during transplantation

107 platelets, 12.5 +/- 5.4 U vs. 8.6 +/- 6.4 U; fresh frozen plasma, 9.6 +/- 4.9 U vs. 4.9 +/- 3.6 U; an

108 core analysis adjusting by use of platelets, fresh frozen plasma, and cryoprecipitate; and adjusting

109 h a 68%, 56%, and 58% reduction in platelet, fresh frozen plasma, and packed erythrocyte usage, respe

110 used patients, pooled platelet concentrates, fresh frozen plasma, and packed red cells collected usin

111 ng administration of packed red blood cells, fresh frozen plasma, and platelets in ratios approximati

112 The administration of coagulation factors (fresh frozen plasma, prothrombin complex concentrates or

113 ontinued, and treatment with plasmapheresis, fresh frozen plasma, steroids, and OKT3 was begun.

114 apy and treatment with lactulose, vitamin K, fresh frozen plasma, ventilatory assistance, and intensi

115 Fresh frozen plasma-to-packed RBCs and platelets-to-pack

116 The benefits of higher ratios of fresh frozen plasma-to-packed RBCs and platelets-to-pack

117 ion for patients receiving and not receiving fresh frozen plasma.

118 and avoidance of preemptive transfusions of fresh frozen plasma.

119 2,058 nontrauma patients who did not receive fresh frozen plasma.

120 o did receive red blood cells in addition to fresh frozen plasma.

121 r bias improved survival outcome with higher fresh frozen plasma: red blood cell ratios.

122 ts (0.1 [0.04] vs 1.9 U [4.5] p=0.0001), and fresh-frozen plasma (0.1 [0.07] vs 0.75 U [0.21] p=0.000

123 ross as a virally inactivated alternative to fresh-frozen plasma (FFP).

124 use of a combination of packed red cells and fresh-frozen plasma (reconstituted blood) for priming of

125 The dose of fresh-frozen plasma administered was highly variable (me

126 ulopathy unresponsive to vitamin K requiring fresh-frozen plasma after the first 24 hours postresecti

127 both platelets and coagulant products (e.g., fresh-frozen plasma and recombinant-activated factor VII

128 Transfused red cells, platelets, and fresh-frozen plasma can transmit West Nile virus.

129 use of a combination of packed red cells and fresh-frozen plasma during surgery for congenital heart

130 anticoagulation, and/or plasmapheresis with fresh-frozen plasma exchange, resolved TMA in most patie

131 The severe group required more fresh-frozen plasma intraoperatively than the mild group

132 six allografts lost, despite treatment with fresh-frozen plasma or plasmapheresis.

133 re frequent recurrences, and prescription of fresh-frozen plasma prophylaxis.

134 VE than the PVE group, as were postoperative fresh-frozen plasma requirements.

135 Fresh-frozen plasma should be given for documented defic

136 nternational normalized ratios, 33% received fresh-frozen plasma transfusions during their intensive

137 Wide variation in fresh-frozen plasma treatment exists suggesting clinical

138 Fifty-one percent of fresh-frozen plasma treatments were to nonbleeding patie

139 from 7.8% to 92.8% for RBCs, 0% to 97.5% for fresh-frozen plasma, and 0.4% to 90.4% for platelets.

140 e vWf-cleaving metalloprotease is present in fresh-frozen plasma, in cryoprecipitate-depleted plasma

141 ive bleeding disorder treated by infusion of fresh-frozen plasma, plasma-derived FVII concentrates an

142 and nonleukoreduced red cells, platelets, or fresh-frozen plasma.

143 n profiling was performed in 140 samples, 47 fresh frozen samples and 93 FFPE samples, on HU133_Plus_

144 nt data sets that used similar platforms and fresh frozen samples, the average differences were 11% t

145 are currently limited by the availability of fresh frozen samples.

146 values were comparable to those observed in fresh frozen samples.

147 imens are concordant with ChIP-seq data from fresh-frozen samples of the same tumors.

148 genome-wide expression profiling studies of fresh-frozen samples were validated in the formalin-fixe

149 in reaction (qRT-PCR) from 114 corresponding fresh-frozen samples.

150 Fresh-frozen sections of corneas from an 18-year-old and

151 ied to detect Fas and Fas ligand proteins in fresh-frozen sections of normal human cornea.

152 estigated by immunohistochemical analysis of fresh frozen skin specimens using multiple lymphocytic m

153 tide polymorphism microarray platform, of 60 fresh-frozen specimens that represent the main salivary

154 Fresh frozen tissue from 232 patients (T3-4, N0, M0) wit

155 Mass spectra are acquired directly from fresh frozen tissue sections using matrix-assisted laser

156 We compared fresh frozen tissue, fresh frozen endoscopic brushings,

157 s of photoreceptors were microdissected from fresh frozen tissue, RNA was purified, and quantitative

158 ings demonstrate for the first time that, in fresh frozen tissue, that the anatomical distribution of

159 alyses have been restricted to patients with fresh-frozen tissue and limited follow-up.

160 Fresh-frozen tissue samples were collected for genomic a

161 ly quenched activity-based probes (qABPs) to fresh-frozen tissue samples.

162 trometry profiles from 10-microm sections of fresh-frozen tissue samples: 25 normal lung, 29 normal b

163 In this method, fresh-frozen tissue sections are fixed, incubated with t

164 (PLC) to near-quantitatively degrade PCs in fresh-frozen tissue sections.

165 Fresh-frozen tissue, microsatellite instability status,

166 hylation-Specific PCR (MSP), performed using fresh-frozen tissue, was used to determine the methylati

167 issue; (2) blood and its components; and (3) fresh/frozen tissue from breast cancer trials.

168 eveloped for blood, serum, plasma, FFPE, and fresh/frozen tissue.

169 ing human lung cancer tissue microarrays and fresh frozen tissues, we found that the overexpression o

170 ed and purified from 134 tissue samples from fresh-frozen tissues (n = 87) or formalin-fixed, paraffi

171 By using microdissection of fresh-frozen tissues and recombinant isolation of RNA se

172 in human studies is often restricted because fresh-frozen tissues are not available.

173 Fresh-frozen tissues available from seven patients and C

174 dy epigenetics in clear-cell ovarian cancer, fresh frozen tumor DNA (n = 485) was assayed on Illumina

175 number and LOH profiles from paired FFPE and fresh frozen tumor samples.

176 Therefore, we examined B7-H4 expression in fresh-frozen tumor specimens from 259 renal cell carcino

177 , copy number profiling was limited to large fresh-frozen tumors where intact DNA could be readily ex

178 spar, and Cryptosporidium parvum in fresh or fresh, frozen, unfixed human fecal specimens.

179 n aqueous extracts of human fecal specimens (fresh, frozen, unfixed, or fixed in 5 or 10% formalin or

180 cedures used in pathology, we selected small fresh frozen uterine tissue samples to investigate how t

181 was performed on genomic DNA extracted from fresh-frozen whole blood and patient-matched tumor pairs

182 zed from isolated pancreatic islets and from fresh-frozen whole pancreatic tissue using PCR and seque