ライフサイエンスコーパス: frustrate

1 mplies that protein structures are minimally frustrated.

2 rovides a SCO behavior that is intrinsically frustrated.

3 ynamo properties persist at high Rm has been frustrated.

4 ng plant drought tolerance models, have been frustrated.

5 at usually order if the lattices are not too frustrated.

6 Itch is immensely frustrating.

7 This is largely because of a frustrating 20+ million-year gap in the mid-Cretaceous f

8 typical density of dislocations could fully frustrate a canonically unfrustrated system.

9 on scattering study of CoAl(2)O(4), a highly frustrated A-site spinel.

10 e range from 30 mK to 300 K suggest strongly frustrated AFM interactions on the scale of J/kb approxi

11 Theoretical modeling confirms a frustrated aggregation process in superfluid helium due

12 Epistatic interactions can frustrate and shape evolutionary change.

13 It is geometrically frustrated and has a peculiar fractal dimension.

14 crostates because they are usually minimally frustrated and may interconvert on the micro- to millise

15 g the treatment of ureteral stones can prove frustrating and increases both healthcare cost and patie

16 The most susceptible, frustrating and often most interesting samples are those

17 hat has previously been prepared is indeed a frustrating and potentially serious problem for solid-st

18 I find these calls frustrating and unnecessarily decisive.

19 In2 O3 :PVP weight ratio, crystallization is frustrated, and conducting pathways for efficient charge

20 spectrum in YbMgGaO4, the effective spin-1/2 frustrated antiferromagnet on the triangular lattice, as

21 Here, we engineer frustrated antiferromagnetic interactions between spins

22 nd mutual inhibition that generated locally "frustrated" antiferromagnetic states.

23 magnetostatic interactions in geometrically frustrated arrangements of nanoelements called artificia

24 constructed and experimentally investigated frustrated arrays of dipoles forming two-dimensional art

25 cking of any twisted bundle is geometrically frustrated, as it makes the sixfold geometry of filament

26 One of the most frustrating aspects of treating psoriasis is the tendenc

27 mission, stigma, and sexual desire) and felt frustrated at the perceived intractability of some of th

28 This is especially frustrating at a time when a panoply of molecularly targ

29 sing many of the difficulties that currently frustrate attempts to employ SVs in association testing.

30 he promiscuous nature of cAMP signaling have frustrated attempts to determine the underlying mechanis

31 o animal or plant species remains contested, frustrating attempts to estimate how many such units the

32 implications of impaired autophagic flux or frustrated autophagy.

33 ng new facts and skills in succession can be frustrating because no sooner has new knowledge been acq

34 It is characterized by frustrated bond cleavage, after which the two incipient

35 These interactions can be productive or frustrating but are always time-consuming.

36 ent modalities for this therapeutically very frustrating, but biologically fascinating, group of dise

37 ification of PDA molecular subtypes has been frustrated by a paucity of tumor specimens available for

38 Eukarytotic gene expression is frustrated by a series of steps that are generally not o

39 s to establish causality will continue to be frustrated by an inability of footprinting to identify t

40 n layer of cholesteric liquid crystal (CLC), frustrated by homeotropic anchoring conditions, and reli

41 but that their suicidal tendencies are often frustrated by injunctive social norms.

42 Elucidating cardiac evolution has been frustrated by lack of fossils.

43 re to explore opaque materials is ordinarily frustrated by multiple scattering of waves, attention ha

44 under nonequilibrium conditions are usually frustrated by poor knowledge of the atomic processes of

45 he precise role of this interaction has been frustrated by the complex pleiotropic phenotype exhibite

46 to limit the impact of invasive species are frustrated by the cryptogenic status of a large proporti

47 aneous melanoma, but complete remissions are frustrated by the development of acquired resistance.

48 supported by enhanced exchange couplings are frustrated by the effects of delocalized electrons.

49 ewhat unfortunately, these efforts are often frustrated by the formation of structures lacking long-r

50 understanding of these computations has been frustrated by the lack of detailed synaptic connection m

51 ions: typical bidentate H-bonding by Dopa is frustrated by the longer spacing of OH-SAMs; in contrast

52 Diagnosis of enteric fever remains frustrated by the nonspecific clinical presentation of c

53 tabolites with improved properties are often frustrated by the unpredictability and complexity of the

54 Nanochemists are often frustrated by the well-known fact that no two nanopartic

55 complexes in both oxidation states have been frustrated by unpredictable reactivity in cerium(III) ox

56 additional -omics data, this quest has been frustrated by various theoretical and technical hurdles,

57 ictors of poor job satisfaction were feeling frustrated by work (ie, a burnout item) (OR: 37), worryi

58 l manipulation, complex-shaped colloids, and frustrated cholesterics.

59 tion task completed under nonfrustrating and frustrating conditions.

60 In "frustrated" conjugates where the centrosome is stuck beh

61 ay result from the distinct distributions of frustrated contacts in each complex.

62 dues suggest structural strain, arising from frustrated contacts, is present in the native dimer.

63 vapor deposited, DPT's pendant phenyl groups frustrate crystal growth, yielding amorphous films.

64 ure imposed by the emulsion droplet leads to frustrated crystallization.

65 d state that emerges from the coupled highly frustrated Delta-chain magnetic topology of the alternat

66 sible quantum liquids of electric dipoles in frustrated dielectrics open up a fresh playground for fu

67 ues of quantum spin liquids, could emerge in frustrated dielectrics where antiferroelectrically coupl

68 ss of reaction in which a molecule undergoes frustrated dissociation to radicals, followed by an intr

69 )(CoCp2(+))3] in an organic glass has a spin-frustrated doublet ground state and a thermally accessib

70 These competing effects frustrate efforts to design and engineer stable, active

71 onuniformly, but fundamental physical limits frustrate efforts to detect the resulting temperature gr

72 intrinsic flexibility of these peptides has frustrated efforts to investigate the secondary and tert

73 asurements of bulk cell population that have frustrated efforts to resolve cellular states.

74 iability of single-cell RNA-seq measurements frustrates efforts to assay transcriptional differences

75 cies' responses, together with limited data, frustrates efforts to forecast the consequences of ongoi

76 crown ethers are typically highly flexible, frustrating efforts to rigidify them for many uses that

77 and two-spin exchange J supplemented with a frustrated electron 'ring-exchange' term, which we here

78 n-state ensembles (TSE) and providing a less frustrated energy landscape between the unfolded and TS

79 These data depict a frustrated energy landscape for interactions involving i

80 ical work showing that a funneled, minimally frustrated energy landscape is sufficient to fold small

81 erned by native-like contacts on a minimally frustrated energy landscape.

82 and radii of gyration suggest that the less frustrated energy landscapes for optimized variants are

83 to the receptor/estrogen complex, inducing a frustrated ensemble of suboptimal hydrogen bond networks

84 Unfortunately, this can be a frustrating experience because database searches often m

85 These differences frustrate experimental biologists and ecotoxicologists w

86 itude lower temperature in the geometrically frustrated f.c.c. polymorph (Neel temperature T(N) = 2.2

87 logous to the Curie transition in simple and frustrated ferro- and antiferromagnets; here spin flips

88 To investigate the factors that frustrate folding, we have made mutations in the N-termi

89 C-CL-CC results in mismatched registers that frustrate folding.

90 naturally occurring wild-type proteins have frustrated folding landscapes due to the surface electro

91 can be debilitating, difficult to treat, and frustrating for patients and physicians.

92 acilitates lattice distortion can be used to frustrate free relaxation of the lattice distortion, the

93 ume, sampling and research effort especially frustrates global-scale diversity reconstructions.

94 g macrocyclic triradical trianions with spin-frustrated ground states and accessible 1D pores offers

95 One approach has been to make use of frustrated growth of the supramolecular assembly by tuni

96 s in mammalian PrP(C), they are localized in frustrated helices H2 and H3 where most of the pathogeni

97 h because of their sequence compositions are frustrated in the helical state.

98 The network of minimally frustrated interactions encompasses the folding core of

99 Frustrated interactions exist throughout nature, with ex

100 ographically patterned bar magnets mimic the frustrated interactions in real materials but are also a

101 nanostructures enable the study of competing frustrated interactions with more control over the syste

102 rs of spins, the ground states of which (for frustrated interactions) cannot be simulated on a classi

103 simple topology and has evolved to minimize frustrated interactions.

104 Magnetic materials having competing, i.e., frustrated, interactions can display magnetism prolific

105 Here we realize a quantum simulation of frustrated Ising spins in a system of three trapped atom

106 This polymorphic nature of Abeta has frustrated its biophysical characterization, its structu

107 and discusses some of the problems that have frustrated its wide use on an industrial scale.

108 This geometrically frustrated kagome antiferromagnet is one of the best can

109 ws rich behaviour when spins occupy a highly frustrated lattice such as kagome.

110 cis structure directing properties, lead to frustrated lattices owing to the competing ferro and ant

111 can emerge from the nominal ground states of frustrated lattices.

112 magnetic interactions within and between the frustrated layers.

113 pic exchange interactions which, when highly frustrated, lead to an exotic state of matter known as t

114 behavior in systems that possess no obvious frustrated Lewis acid-base interaction.

115 nich-type reaction catalyzed by a sterically frustrated Lewis acid/Bronsted base complex is disclosed

116 e transformation is promoted by a sterically frustrated Lewis acid/Bronsted base pair, which is propo

117 hane with Piers' borane [HB(C6F5)2] gave the frustrated Lewis pair (FLP) 4 in good yield.

118 The tetramethylene-bridged PMes2/B(C6F5)2 frustrated Lewis pair (FLP) 8 was prepared by hydroborat

119 Two novel frustrated Lewis pair (FLP) aminoboranes, (1-Pip-2-BH2-C

120 phosphine, acts as a purely phosphorus-based frustrated Lewis pair (FLP) and abstracts hydride from [

121 s a Zr(II) metal Lewis base/boron Lewis acid frustrated Lewis pair (FLP) and undergoes typical regios

122 Frustrated Lewis pair (FLP) chemistry enables a rare exa

123 Despite the rapid development of frustrated Lewis pair (FLP) chemistry over the last ten

124 otifs, mimicking the basic sites employed in frustrated Lewis pair (FLP) chemistry, were synthesized

125 xidation reactions are rarely encountered in frustrated Lewis pair (FLP) chemistry.

126 on of NO with the intramolecular bridged P/B frustrated Lewis pair (FLP) endo-2-(dimesitylphosphino)-

127 l spacer; Mes=2,4,6-Me3 C6 H2 ), acting as a frustrated Lewis pair (FLP) in small-molecule activation

128 The vicinal frustrated Lewis pair (FLP) mes2P-CH2CH2-B(C6F5)2 (3) re

129 The intramolecular frustrated Lewis pair (FLP) Mes2PCH2CH2B(C6F5)2 4 adds c

130 enyl)phenyl) was treated with the well-known frustrated Lewis pair (FLP) PtBu3 /B(C6 F5 )3 in varying

131 ometric reactivity, Lewis acid catalysis and frustrated Lewis pair (FLP) reactivity are reviewed.

132 The first example of a frustrated Lewis pair (FLP) solely constructed around tr

133 uct with 4-(N,N-dimethylamino)pyridine but a frustrated Lewis pair (FLP) with the weaker base 2,6-lut

134 3COSiEt3 (3) and finally to CH4] through the frustrated Lewis pair (FLP)-type Si-H activation.

135 O2 led to the instantaneous formation of the frustrated Lewis pair (FLP)-type species [ReHBr(NO)(PR3)

136 Complex 14 behaves as a reactive Zr(+)/amine frustrated Lewis pair (FLP).

137 synthetically accessible and functions as a Frustrated Lewis Pair (FLP).

138 (2a) reacts with diphenylacetylene to yield frustrated Lewis pair [Cp2Zr(PhCCPh)(PCy2)][MeB(C6F5)3]

139 The intramolecular cyclohexylene-bridged P/B frustrated Lewis pair [Mes(2)P-C(6)H(10)-B(C(6)F(5))(2)]

140 A frustrated Lewis pair accessory functionality is positio

141 ts were employed as Lewis acid components in frustrated Lewis pair activation of H2 and CO2.

142 used to pioneer our combined electrochemical/frustrated Lewis pair approach.

143 incorporation of a transition-metal oxo in a frustrated Lewis pair can have a synergistic effect and

144 e how H2 can be preactivated using classical frustrated Lewis pair chemistry and combined with in sit

145 While a number of comprehensive reviews into frustrated Lewis pair chemistry have been published in r

146 Here we report the application of frustrated Lewis pair chemistry to the synthesis of boro

147 raction of the Te and B with the alkyne in a frustrated Lewis pair fashion in the transition states.

148 meta-carbon atom, which generates 1'' with a frustrated Lewis pair in the ring between N and C.

149 amine-boranes by a dimethylxanthene-derived frustrated Lewis pair is described.

150 Mechanistic studies suggest a frustrated Lewis pair is generated between the oxorheniu

151 the metal-free C-H insertion proceeds via a frustrated Lewis pair mechanism involving heterolytic sp

152 ation of aldimines at room temperature via a frustrated Lewis pair mechanism.

153 In contrast to traditional frustrated Lewis pair systems, the lack of steric hindra

154 these cases the borane and ether behave as a frustrated Lewis pair to activate H2 and effect the redu

155 Complex 10 acts as a reactive frustrated Lewis pair toward heterocumulenes, undergoing

156 The latter mediates frustrated Lewis pair type Si-H bond activation of the s

157 The trimethylene-bridged amine/borane frustrated Lewis pair was prepared by hydroboration of N

158 tion conditions, are found to proceed via a "frustrated Lewis pair" mechanism in which the solvent, a

159 cooperatively, in a manner reminiscent of a frustrated Lewis pair, to activate small molecules such

160 showed typical reactions of an oxygen/boron frustrated Lewis pair.

161 Geminal frustrated Lewis pairs (FLPs) are expected to exhibit in

162 We report intermolecular transition metal frustrated Lewis pairs (FLPs) based on zirconocene arylo

163 We report a new class of frustrated Lewis pairs (FLPs) by the hydroboration of bu

164 Frustrated Lewis pairs (FLPs) comprising sterically hind

165 It was found that the surface frustrated Lewis pairs (FLPs) created by a Lewis acidic

166 Recent progress in frustrated Lewis pairs (FLPs) has attracted increasing a

167 esign strategies than can lead to metal free frustrated Lewis pairs (FLPs) that can be employed for A

168 oxidation of H2 by combining the ability of frustrated Lewis pairs (FLPs) to heterolytically cleave

169 2 is a strong Bronsted base that forms frustrated Lewis pairs (FLPs) with a number of boron-con

170 eactivity bear resemblance to the concept of frustrated Lewis pairs (FLPs), some of which have been s

171 trong bonds between Lewis acids and bases in frustrated Lewis pairs (FLPs), where latent reactivity m

172 ssance due to the fascinating development of frustrated Lewis pairs (FLPs).

173 ret the facile heterolytic cleavage of H2 by frustrated Lewis pairs (FLPs).

174 The C4-bridged unsaturated phosphane/borane frustrated Lewis pairs (P/B FLPs) 4 undergo borane induc

175 for dihydrogen activation by silyl cationic frustrated Lewis pairs and in general for the dihydrogen

176 Frustrated Lewis pairs have found many applications in t

177 es that the metal-free activation of N2 with frustrated Lewis pairs may be achievable in the not-too-

178 -butyl (tBu), mesityl (Mes), naphthyl (Nap)] frustrated Lewis pairs react with N2O to form species ha

179 oaddition of C(2)-bridged intramolecular P/B frustrated Lewis pairs to nitric oxide.

180 vicinal M(+)/P systems 4 behave as reactive frustrated Lewis pairs toward hetercumulenes, undergoing

181 tionalities have been probed in a series of "frustrated Lewis pairs" (FLPs) (mainly substituted vinyl

182 The articulation of the notion of "frustrated Lewis pairs" (FLPs), which emerged from the d

183 In recent years 'frustrated Lewis pairs' (FLPs) have been shown to be eff

184 ttributable to the development of so-called 'frustrated Lewis pairs': unquenched combinations of bulk

185 strong TMP-bases with BF3.OEt2 (formation of frustrated Lewis pairs) dramatically increases the scope

186 e of H2 into a proton and a hydride, akin to frustrated Lewis pairs.

187 mination reaction catalyzed by a sterically "frustrated" Lewis acid/Bronsted base complex is disclose

188 A bulky, strong phosphazene base forms a "frustrated" Lewis pair (FLP) with a trialkylborane in th

189 rong silane activation, effects multifaceted frustrated-Lewis-pair-type catalysis.

190 completely compensating entropic penalties, frustrating ligand design.

191 Achieving uniform lattice orientation in frustrated liquid-crystalline phases, like cubic blue ph

192 Inherent disorder at the Fe/Li mixed site frustrates long-range communication between magnetic cen

193 el of the spin-liquid state in the canonical frustrated magnet gadolinium gallium garnet (Gd3Ga5O12).

194 The case in point is a frustrated magnet, where spins are arranged in a triangu

195 ements on fully oxygenated films indicated a frustrated magnetic ground state characterized as a spin

196 ested paramagnetic Fermi surface mediate the frustrated magnetic interactions between local moments.

197 Dy2Ti2O7 has become of interest because its frustrated magnetic interactions may, in theory, lead to

198 ples ranging from protein folding through to frustrated magnetic interactions.

199 ing Dirac electrons, strong interactions and frustrated magnetic interactions.

200 Frustrated magnetic lattices offer the possibility of ma

201 Frustrated magnetic materials are promising candidates f

202 Among the frustrated magnetic materials, spin-ice stands out as a

203 This provides experimental evidence that a frustrated magnetic metamaterial can be engineered to ad

204 pect, artificial spin ices are geometrically frustrated magnetic metamaterials that offer vast untapp

205 Artificial spin ices are frustrated magnetic nanostructures where single domain n

206 Frustrated magnetic systems exhibit highly degenerate gr

207 However, in many geometrically frustrated magnetic systems, conventional LRO is suppres

208 For instance, frustrated magnetism is a hallmark of poorly understood

209 es as a model for the study of geometrically frustrated magnetism.

210 irection of exchange and leading to strongly frustrated magnetism.

211 Frustrated magnets are materials in which localized magn

212 lated materials, spin-orbit Mott insulators, frustrated magnets, and dilute magnetic alloys.

213 cs, currently most researches are focused on frustrated magnets, which usually have complicated magne

214 A good example is the quantum spin liquid in frustrated magnets.

215 to explore novel phenomena of geometrically frustrated magnets.

216 We predict that several (frustrated) magnets with dominant direct exchange and no

217 etric constraints, which suggests that other frustrated materials may possess unusual surface charact

218 c properties of a new series of magnetically frustrated materials, Mg(x)Cu(4-x)(OH)(6)Cl(2).

219 PdCrO2, a frustrated metallic magnet, offers the opportunity to ex

220 n-by-design concept can deliver magnetically frustrated metamaterials.Artificial magnetic nanostructu

221 , attributed to non-native helical structure frustrating microsecond refolding.

222 ition, we studied simulations of a minimally frustrated model based on energy landscape theory.

223 performs the tungsten radiator, dominated by frustrated modes, only for a vacuum gap thickness of 10

224 polarized light can provide a knob to drive frustrated Mott insulators into a chiral spin liquid, re

225 he two bridges are critical for snapping the frustrated native structure into place.

226 Frustrated networks have highly degenerate ground states

227 quire regions of negative cooperativity, or "frustrated" noncovalent interactions, as a source of pot

228 tive state contains structural elements that frustrate one another's folding, and that the two bridge

229 evidence that pyrogallol[4]arenes may act as frustrated organic solids.

230 loidal particles immersed in liquid crystals frustrate orientational order.

231 topped-flow FRET studies indicated that such frustrated packing leads to accelerated dissociation of

232 nds between folding and function, regions of frustrated patterns are present at the active site of pr

233 Our investigation reveals that frustrated phagocytic spreading occurs in phases and is

234 To overcome these issues, we use a series of frustrated phagocytosis assays to quantitatively charact

235 the localization of PA in macrophages during frustrated phagocytosis was examined using these PA sens

236 Together, these studies challenge the "frustrated phagocytosis" concept and suggest that neuron

237 F-actin is reorganized during the course of frustrated phagocytosis.

238 The observed frustrated phase is a template for similar ordering in o

239 ility of homogeneous FeS(2-x)O(x) alloys and frustrates phase separation into FeS(2) and iron oxides.

240 quivocally probe the association between the frustrated PR3/B(C6F5)3 (1, R = CMe3; 2, R = 2,4,6-Me3C6

241 Recruiting PhD students can be a frustrating process, but Eve Marder looks forward to wel

242 ccustomed to its use is a daunting and often frustrating process.

243 Our results show how the physics of frustrated pyrochlore magnets such as spin ice may be si

244 ulation points the way toward a new probe of frustrated quantum magnetism and perhaps the design of n

245 Frustrated quantum magnets not only provide exotic groun

246 The search for quantum spin liquids in frustrated quantum magnets recently has enjoyed a surge

247 In frustrated quantum magnets, long-range magnetic order fa

248 Topological phases in frustrated quantum spin systems have fascinated research

249 t with additional alane to generate proposed frustrated radical ion pairs formulated as [R3P.][(mu-O.

250 In condensed matter, the frustrated rare-earth pyrochlore magnets Ho2Ti2O7 and Dy

251 ave proposed that this roughness is due to a frustrated search for the correct docking of partly pref

252 h either a strong spin-orbital coupling or a frustrating second-nearest-neighbor coupling is expected

253 Hence, the design of minimally frustrated sequences can reduce chaperonin dependence an

254 rgy surface rough with local minima trapping frustrated species.

255 ch as ferromagnetic, anti-ferromagnetic, and frustrated spin configurations on a linear chain, the un

256 er weak magnetic fields, indicating strongly frustrated spin interactions.

257 hedra is described which enables interesting frustrated spin lattices to be targeted.

258 c degrees of freedom.Experimental studies of frustrated spin systems such as pyrochlore magnetic oxid

259 Of particular significance is the hunt for frustrated spin-1/2 networks as candidates for quantum s

260 BiCu2PO6 is a unique frustrated spin-ladder compound exhibiting highly anisot

261 nt electrons rarely coexist in geometrically-frustrated spinel lattices.

262 etween Mott and Slater physics, where a spin-frustrated state emerges at the crossover.

263 This frustrating state of affairs calls for a fundamental cha

264 target structure, by avoiding (encountering) frustrated states.

265 a small bioactive peptide to bring together frustrated structure in addition to maintaining protein

266 complete sterility of surviving F(1) hybrids frustrated Sturtevant and his vision of comprehensively

267 perfect match to the expected behavior for a frustrated system with the lowest energy pair of S=1/2 s

268 , we provide a first look into an artificial frustrated system, the dipolar trident lattice, where th

269 scopic insight into this novel geometrically frustrated system.

270 Spin-frustrated systems are one avenue for inducing macroscop

271 cenario might be expected to occur widely in frustrated systems containing first-order phase transiti

272 Frustrated systems, typically characterized by competing

273 o be an improvement; consequently, they were frustrated that it was differentiated from and not coher

274 r, reveal that the apo protein is internally frustrated, that these internal stresses are partially r

275 e different isoforms are able to nucleate or frustrate the assembly of each other.

276 s which involves bulky directing groups that frustrate the crystal packing.

277 tially conflicting selection forces that can frustrate the Darwinian evolutionary process of affinity

278 These inaccuracies in turn frustrate the development of archaeological chronologies

279 re much lower than today, yet open questions frustrate the translation of modern measurements of sulf

280 ecific binding at the crystal surface, which frustrates the attachment of L-cystine molecules.

281 aterials prevent complete ingestion and this frustrates the cell.

282 ce the magnitude of NTE/NLC) but selectively frustrates the soft phonon modes responsible for destroy

283 o curb the hepatitis C epidemic, rather than frustrate them.

284 Results Some PCPs felt compelled but frustrated to pursue costly follow-up for incidental ima

285 The bacterial causes of diarrhea can be frustrating to identify, and it is likely that many rema

286 lectric performance of p-type Bi2Te3, it was frustrating to researchers that they proved ineffective

287 nsional, that is, molecular, structures with frustrated topologies.

288 The highly frustrated topology of the inorganic slabs, along with t

289 ere we describe one such approach based upon frustrated total internal reflection imaging that can be

290 To study this phenomenon, we use frustrated total internal reflection to image the asperi

291 riability inherent in clinical injuries will frustrate translation.

292 perature, the interplay of superradiance and frustrated triplet diffusion contributes to a nearly 20-

293 r modifying the tips of tubes may help avoid frustrated uptake by cells.

294 utations at positions predicted to be highly frustrated were found to correlate with decreased GroEL

295 A network is frustrated when competing interactions between nodes pre

296 alization of such possibilities is typically frustrated when such specialized molecules are integrate

297 These difficulties are particularly frustrating when the goal is to determine the role(s) th

298 the ocular fundus was found easier and less frustrating when using photographs than when using ophth

299 cape, R16 and R17 can circumvent their slow, frustrated wild-type folding mechanism.

300 njury struggled to be hopeful whilst feeling frustrated with the process of treatment and recovery.