ライフサイエンスコーパス: fucosyl

1 ns are occasionally substituted with alpha-l-fucosyl.

2 ecause of the absence of a conserved alpha-L-fucosyl-(1-->2)-beta-D-galactosyl side chain and excessi

3 (1-->2)-alpha-D-xylosyl-(1--> and/or alpha-L-fucosyl-(1-->2)-beta-D-galactosyluronic acid-(1-->2)-alp

4 hyl-beta-D-galactopyranosyl-(1-->4)-[alpha-L-fucosyl-(1-->6) ]-beta-D-glucopyranoside (2a), has been

5 fucosyl lactose but were not active with 2'- fucosyl-6'-sulfo lactose.

6 UR3 genes of Arabidopsis encode XyG-specific fucosyl and galactosyl transferases, respectively.

7 C. elegans-specific fucosyl and native methylated glycans were found in all

8 d, attributed to shape irregularities of the fucosyl branches on an otherwise linear core, being more

9 oglucan, but that the molecular mass and the fucosyl content of the substrates influence enzymatic re

10 At 6 mo, each 1-mug/mL increase in fucosyl-disialyl-lacto-N-hexaose and lacto-N-neotetraose

11 te-beta-l-fucose (GDP-fucose), the universal fucosyl donor, the Le(x) trisaccharide, and their C-5 su

12 charide acceptor moieties, 25 or 26, and the fucosyl donors, 10 and 11, were conducted using similar

13 S group inferred unusual reactivity on these fucosyl donors.

14 ides and intact glycoproteins by using alpha-fucosyl fluoride as a simple donor substrate.

15 Expression of these rice genes, including fucosyl-, galactosyl-, and acetyltransferases, in the co

16 cer-associated antigens globopentaose (Gb5), fucosyl-Gb5 (Globo H), and sialyl-Gb5 (SSEA4) by using o

17 t tumor-associated antigens (fucosyl-GM1 and fucosyl-Gb5), were unambiguously confirmed by 1H-NMR spe

18 cceptorsubstrate specificity toward alpha1,6-fucosyl-GlcNAc-Asn or alpha1,6-fucosyl-GlcNAc-polypeptid

19 ward alpha1,6-fucosyl-GlcNAc-Asn or alpha1,6-fucosyl-GlcNAc-polypeptide in transglycosylation, enabli

20 round of reduced core-1 O-glycans, the novel fucosyl glycans likely replace or mask remaining core-1

21 otected using standard procedures to provide fucosyl GM1 oligosaccharide (1) in 44% yield.

22 s of the novel small cell lung cancer (SCLC) fucosyl GM1-based vaccine construct, featuring insertion

23 de synthesis methodology to the synthesis of fucosyl GM1.

24 n to be important tumor-associated antigens (fucosyl-GM1 and fucosyl-Gb5), were unambiguously confirm

25 nding to multiple GM1 isoforms as well as to fucosyl-GM1, which is a known ligand.

26 om the alphaGal epitope by the presence of a fucosyl group.

27 as located to quantitate possible changes of fucosyl isomeric species associated with the pathologica

28 ctal cancer, being primarily associated with fucosyl isomers.

29 The kinetics for GalNAc transfer to 2'-fucosyl lactose are characteristic of a sequential mecha

30 , 9%, and 188% active, respectively, with 2'-fucosyl lactose but were not active with 2'- fucosyl-6'-

31 s and concurrent introduction of two alpha-L-fucosyl moieties at the late stage of the syntheses prov

32 Here we characterize the CD15 (3[alpha1-3]-fucosyl-N-acetyl-lactosamine)-positive cells in the mous

33 e-1 glycans are decreased, whereas the novel fucosyl O-glycans are increased in abundance in this reg

34 ogue, and modified structures containing 3-O-fucosyl or 6-O-sulfo substituents in the N-acetylglucosa

35 A series of sialyl fucosyl poly-N-acetylgalactosamine gangliosides without

36 Thus, the presence of a fucosyl residue appears to be obligatory for an oligosac

37 a single methyl group to the 2-position of a fucosyl residue in one of the five O-chain trisaccharide

38 y affected by the presence of an alpha 1,6-L-fucosyl residue located on the distant glucosaminyl resi

39 (mannose3-N-acetylglucosamine2), most with a fucosyl residue on the innermost N-acetylglucosamine.

40 The addition of an alpha 3-fucosyl residue to each of these two competitive inhibit

41 ose of dicotyledonous plants, has a terminal fucosyl residue.

42 pproximately 25% of the 3,4-linked branching fucosyl residues and 10% of the 3-linked fucosyl residue

43 ing fucosyl residues and 10% of the 3-linked fucosyl residues are 2-O-methylated.

44 s the regiospecific transfer of terminal 1,2-fucosyl residues to xyloglucan side chains - a key step

45 ess xylosylated (XXGGn core motif) and lacks fucosyl residues.

46 thaliana) XyG, which contains galactosyl and fucosyl substituents, tomato (Solanum lycopersicum) XyG

47 ights into the molecular mechanisms by which fucosyl sugars contribute to neuronal processes.

48 Galalpha-O-Me] structures containing sialyl, fucosyl, sulfo, methyl, or fluoro substituents by identi

49 that partially purified KpsS functions as a fucosyl sulphotransferase in vitro.

50 A mechanism for fucosyl transfer incorporating these findings is propose

51 eins as potential substrate acceptors in the fucosyl transfer reactions indicated that the two enzyme

52 fucosyl transferase 8 (FUT8) was identified as a potenti

53 ith increasing alpha-mannosidase II and core fucosyl-transferase enzyme activities, and with decreasi

54 1 alone or fucT1 and fucT2, which encode the fucosyl transferases necessary for Le(x) and Le(y) expre