ライフサイエンスコーパス: fulfill @2 role

1 region, the atypical myosin light chains may fulfill that role.

2 lothionein or cellular zinc transporters may fulfill that role.

3 ndicates that Arg93 in NucA is positioned to fulfill this role.

4 second zebrafish mitf gene, mitfb, which may fulfill this role.

5 ent and about how clinicians could help them fulfill this role.

6 set but distinct from natural T(R) cells may fulfill this role.

7 entate gyrus subregion has been suggested to fulfill this role.

8 activating kinases, Sak1, Tos3, or Elm1, can fulfill this role.

9 cognized as an important sequence class that fulfill many roles.

10 space of plastids and we propose that Tic22 fulfills this role.

11 ARC6-like protein unique to vascular plants, fulfills this role.

12 ucing agent is required for the reaction and fulfills two roles.

13 naling pathway is an attractive candidate to fulfill such a role.

14 e stria terminalis (aBST) as a candidate for fulfilling this role.

15 w that inducible cAMP early repressor (ICER) fulfills such a role.

16 FNR proteins that presumably have evolved to fulfill distinct roles.

17 s engaged in retrograde signaling, it cannot fulfill the latter role.

18 se their typical endo-binding mode would not fulfill a targeting role.

19 Another endopeptidase, PBP 7, fulfills a secondary role.

20 merization event, which switches the strands fulfilling these two roles.

21 is not essential for catalysis, and possibly fulfills a structural role.

22 formation is metal-dependent, with the metal fulfilling a structural role.

23 disposal of cell-cycle regulators that have fulfilled their mitotic roles.

24 redundant PSs already present in the genome fulfilling their packaging role.

25 rties of the tandem HMG boxes, presumably to fulfill different cellular roles.

26 e residues are not involved in catalysis but fulfill important structural roles.

27 To fulfill its biological role, a cell globally responds wi

28 /UL131A (Pentamer) complex has been found to fulfill this role, accounting for HCMV entry into almost

29 imply that vertebrate odorant receptors may fulfill a dual role, also serving as address molecules t

30 Divalent ions fulfill essential cellular roles and are required for vi

31 To fulfill its diverse roles and maintain hemostasis, this

32 ursing is dependent on available evidence to fulfill that role and on the sociopolitical and organiza

33 is a fundamental duty of physicians both to fulfill a role as trusted adviser and to promote the eth

34 To fulfill its role as the major energy-storing tissue, adi

35 e COP9 signalosome have been hypothesized to fulfill the roles as an ubiquitin ligase (E3) and an ess

36 ly inhibit the ability of dendritic cells to fulfill their role as antigen-presenting cells.

37 es of oral health and disease if they are to fulfill their role as professionals dedicated to the hea

38 ultiple downstream repair processes, thereby fulfilling its role as a caretaker tumor suppressor.

39 The CytR repressor fulfills dual roles as both a repressor of transcription

40 which confirms that the restored tryptophan fulfills its ancestral role as a core side chain, fillin

41 To understand how micro 1 fulfills its role as the reovirus penetration protein, w

42 a dynamic change in phosphorylation state to fulfill its multiple roles at different stages of viral

43 which is a multifunctional metabolic enzyme fulfilling several metabolic roles (beta-oxidation of fa

44 Hence, we show that cellulose fulfills an adhesion role between the extracellular muci

45 enterochromaffin (EC) cells are proposed to fulfill this role by acting as chemosensors, but underst

46 cell immunity in viral infection and that it fulfills this role by acting as a complement inhibitor t

47 ERRalpha fulfills this role by acting directly at genes important

48 previous information by demonstrating SRC-2 fulfills this role by serving as a critical coactivator

49 iver regeneration after CCl(4) injury, which fulfills multiple roles; C3a generated early after toxin

50 leukin-1 receptor-associated kinases (IRAKs) fulfill key roles downstream of multiple Toll-like recep

51 e, we focus on two intriguing candidates for fulfilling this role, Drosophila Dscams and vertebrate c

52 and its human orthologue Polo-like kinase 1 fulfill essential roles during cell division.

53 Surface proteins of Staphylococcus aureus fulfill many important roles during the pathogenesis of

54 Dynamin may also fulfill other roles during earlier stages of vesicle for

55 Thus, Crb fulfills a protective role during light exposure by limi

56 In polydiacetylenes, the substituents fulfill another important role: During topochemical poly

57 presents a mechanism whereby 1,25(OH)2D3 can fulfill separate functional roles, first in the kidney t

58 function, individual isoforms of PIP5KIgamma fulfill unique roles for the integrin-dependent integrit

59 vation through an ionic mechanism, that A440 fulfills a structural role forming part of the G-protein

60 We conclude that Ile216 and Thr220 fulfill a structural role, forming the foundation of the

61 leotidyltransferases, with the vast majority fulfilling multifunctional roles from DNA replication to

62 However, DAGLs that might fulfill this role have not been previously identified in

63 How katanin fulfills its controlling role, however, remains poorly u

64 oute AGT to the mitochondria where it cannot fulfill its metabolic role (i.e. glyoxylate detoxificati

65 Such services fulfill a crucial role in ensuring transparency and repr

66 e properties of PEP-19 suggest that it could fulfill a role in neuroprotection.

67 ammation--NOD proteins have been proposed to fulfill a role in the intracellular sensing of bacteria.

68 eous plethora of receptors, each tailored to fulfill a vital role in fast synaptic signaling and plas

69 g body of evidence shows that gut microbiota fulfill an important role in health and disease by modul

70 These genes thus appear to fulfill an unexpected role in fostering cell cooperation

71 aped by natural selection as they evolved to fulfill changing functional roles in their native enviro

72 tissues in multicellular organisms, yet they fulfill critical roles in development and normal physiol

73 onal properties suggested that the GDU genes fulfill different roles in roots, vasculature, and repro

74 ractions, tailoring their gating behavior to fulfill distinct roles in neuronal signaling.

75 and ionotropic glutamate receptors (iGluRs) fulfill divergent roles in vertebrate nervous systems.

76 rties, and might therefore act in concert to fulfill essential roles in vivo.

77 Strong RNA binding allows Mss116 to fulfill its biological role in the stabilization of grou

78 To fulfill its role in hemostasis, the platelet is equipped

79 that interact with a variety of proteins to fulfill key roles in signal transduction pathways trigge

80 SRF and its pathway fulfill multiple complex roles in the regulation of the

81 e T cell mediated suggests that some B cells fulfill other roles in autoimmunity.

82 nating oligodendrocytes, NG2 glia might also fulfill physiological roles in CNS homeostasis, although

83 al maintenance of chromosomes (SMC) proteins fulfill pivotal roles in chromosome dynamics.

84 LPs fulfill signaling roles in organisms as diverse as yeast

85 t that other signaling pathways can probably fulfill similar roles in vivo.

86 ndent, suggesting that cyclopentenones could fulfill some JA roles in vivo.

87 contains five imperfect repeating units that fulfill specific roles in directing amyloid formation.

88 , indicate that individual PIP5KI isoenzymes fulfill specific roles in embryonic development.

89 tosis and thus is crucial for neutrophils to fulfill their roles in innate immunity.

90 es of different myosin isoforms are tuned to fulfill these roles in an array of cellular processes, a

91 ted mechanisms have been identified that can fulfill this role in a variety of mammalian cell types,

92 ns, but also show that a tyrosine is able to fulfill this very role in Chlamydomonas reinhardtii cryp

93 Thus, sterols fulfill two roles in mammalian cells: (i) a bulk membran

94 teins containing the STAR RNA-binding domain fulfill vital roles in RNA biogenesis, yet a detailed un

95 ued presence of XORC or XCdc6 once they have fulfilled their essential role in licensing.

96 CCR6-CCL20 to recirculate through the skin, fulfilling a novel role in skin immunity and inflammatio

97 body responses to EGFR hold the potential of fulfilling a pathogenic role in autoimmune disease.

98 ne system can be a cure or cause of disease, fulfilling a protective role in attacking cancer or path

99 omeostatic processes in eukaryotic organisms fulfilling essential roles in development and adaptation

100 In fulfilling its biosynthetic roles in nuclear replication

101 to be the major cellular protease capable of fulfilling such a role in maturation.

102 o be quickly reactivated may be essential to fulfilling the physiological role in cyanobacteria, orga

103 ent anatomical sites in vivo is critical for fulfilling their roles in the induction of Ag-specific i

104 Abeta fulfills a central role in AD pathogenesis, and reductio

105 t TFIIH enters the preinitiation complex and fulfills a critical role in initiation by catalyzing ATP

106 that the von Willebrand (vWA) domain of Ku80 fulfills a critical role in this process by recruiting A

107 MEF2C fulfills a critical role in VSMC differentiation and reg

108 In the retina, dopamine fulfills a crucial role in neural adaptation to photopic

109 otransmitter systems in the brain and mainly fulfills a homeostatic role in terms of neurotransmissio

110 A subpopulation of platelets fulfills a procoagulant role in hemostasis and thrombosi

111 These results indicate that flightin fulfills an essential role in defining the structural an

112 It was concluded that STE50 fulfills an essential role in the activation of the high

113 une responses, and recent studies suggest it fulfills critical roles in CNS function and maintenance.

114 STAT5 fulfills essential roles in hematopoietic stem cell (HSC

115 It fulfills important roles in whole-body lipid handling, s

116 protein, INAF-B, is encoded by the locus and fulfills its critical role in retinal physiology.

117 light on the mechanism by which this protein fulfills its key role in the repair of DNA double-strand

118 NS3, encoded by Seg-10 of the BTV genome, fulfills key roles in BTV infection.

119 cosal surfaces, and secretory component (SC) fulfills multiple roles in this defense.

120 exactly as predicted for a transferase that fulfills the proposed role in the fatty acid synthase re

121 ve ortholog, MITOCHONDRIAL EDITING FACTOR29, fulfills the same role in Arabidopsis thaliana.

122 er hand, mutation of the Arg-82 homolog that fulfills this role in bacteriorhodopsin caused minimal s

123 r optimal integrin activation, and kindlin-3 fulfills this role in hematopoietic cells.

124 This probe fulfills two critical roles in the screen: by locking th

125 ng, vesiculation and internalization process fulfilling numerous roles including compensation of memb

126 In Escherichia coli, components of the PTS fulfill many regulatory roles, including regulation of n

127 One likely candidate to fulfill this role is the anterior cingulate cortex (ACC)

128 We find that PAR signaling fulfills two roles: localizing NMY-2 to the anterior cor

129 he ability of the Office of AIDS Research to fulfill its role of steward of the NIH HIV/AIDS research

130 ss-sectional studies, the field is poised to fulfill its ultimate role of linking defects in molecula

131 wild-type Cdc34 in vitro or in vivo and can fulfill the physiological role of Cdc34 with only modera

132 does imply that both lysine and tyrosine can fulfill the role of an active site proton donor, albeit

133 another cellular amidotransferase is able to fulfill the role of PabA in this organism.

134 functionally equivalent, as only Phox2b can fulfill the role of Phox2a in the structures that depend

135 ntinuous soft structures that simultaneously fulfill the role of robotic link and actuator, where pri

136 d residue (a glutamic acid residue, E) could fulfill the role of the D3 residue, we generated the mut

137 the cell cycle and, therefore, competent to fulfill the role of the transiently proliferating compar

138 vels of thymidine phosphorylation suffice to fulfill the role of the viral enzyme in ganglia and that

139 , and visceral myocytes, which are needed to fulfill the unique roles of the lymphatic system.

140 As well as fulfilling the basic role of protein folding, they may a

141 ose that INS2 allosterically activates PP2C, fulfilling the role of a putative mediator mimetic of in

142 Thus, pyrene also fulfills the plugging role of the Leu191 side chain.

143 Arg96 fulfills the role of an electrophile by lowering the res

144 tial for yeast growth and, by itself, cannot fulfill the essential role played by Cet1p in vivo.

145 In eukaryotes, these channels fulfill numerous biological roles requiring gated anion

146 probably because other Suc transporters can fulfill its role(s).

147 te that flux is maintained in these cells to fulfill other functional roles such as error correction

148 We conclude that Tyr161 fulfills a critical role through its chemical nature and

149 m and lymphocyte development in the rat, OAZ fulfills this role through clusters of fingers that are

150 1 and U6atac snRNPs in the AT-AC spliceosome fulfill analogous roles to U1 and U6, respectively, in t

151 Shallow-water ichthyosaur falls thus fulfilled similar ecological roles to shallow whale fall

152 plasmic B component of enzyme II(Chb), which fulfills an analogous role to IIB(Mtl) in the N,N'-diace

153 ow here that the cancer/testis antigen PASD1 fulfills this role to suppress circadian rhythms.

154 cond signal through CD28 has been thought to fulfill two roles, to stimulate T cell proliferation and

155 e switching from Arg290/Glu167 to Arg290/ATP fulfills a dual role: to destabilize the closed state of

156 Once recruited, FANCD2 fulfills a dual role towards replication fork recovery:

157 To fulfill its role, we show that an effective molecular an

158 infection, suggesting that other kinases can fulfill its role when it is absent.

159 The identification of DCs fulfilling this role will enable future studies to bette

160 However, to fulfill this role without preventing flagellar bend form