ライフサイエンスコーパス: full

1 of filopodia like myosin-X full-length (M10(Full)).

2 ve repeat synthesis, which could restore the full 100 nucleotides of (T2AG3)n lost from replicated c

3 4.9%) with applicable quality indicators had full (100%) adherence to quality indicators compared wit

4 covery.Of 1383 children who returned for the full 12-mo follow-up period, 407 children (56%) and 347

5 gle layer reflective metasurface can achieve full 2pi phase shift coverage without altering the polar

6 ure at the whole-cell scale, by reducing its full 3-D structure to a 3-D network of one-dimensional s

7 ay tomography method is employed to obtain a full 3D structural dataset of the network morphology wit

8 This full account describes a derisking approach toward the r

9 itions were compared with the results of the full acquisition (0-140 min).

10 eins in the trans-Golgi network, followed by full activation by PI4P.

11 On gentle agitation, the SCI retained full activity for >140 days at 45 degrees C and >48 h at

12 serum, and most serum-stable fragments have full activity.

13 After full adjustment, these estimates were numerically simila

14 Finally, a full agent-based model of huddling interactions is also

15 AICP is a full agonist at GluN1/2A (100% response compared with gl

16 We recently reported that tianeptine is a full agonist at the mu opioid receptor (MOR).

17 n and a partial agonist in other assays to a full agonist in all assays.

18 unctional mimetics of H2-RLX with selective, full agonist or positive allosteric modulator activity a

19 worse stomatitis by 8 weeks assessed in the full analysis set (patients who received at least one do

20 100 (40%) of 249 patients in the full analysis set achieved a response, with 19 (8%) achi

21 Analyses were done on the full analysis set, consisting of all randomised patients

22 on, and objective response, analysed for the full-analysis set.

23 Although the conflicting associations in the full and P-VLBW cohorts may reflect true differences, th

24 (positive/negative allosteric modulation or full antagonism) of mGluR5 modulation required to transl

25 In a functional assay, 1b displayed full antagonist activity with IC50 = 6 +/- 2 muM.

26 LT recipients needing full assistance (KPS 10%-40%) vs being independent (KPS

27 ipids in virus replication have been gaining full attention only recently.

28 ps in the continuum is needed to achieve the full beneficial impact of HIV treatment.

29 rol infection may be required to realize the full benefits of CFTR-targeting treatments.

30 ive multifocal leukoencephalopathy (PML) and full-blown immune reconstitution inflammatory syndrome (

31 andomized clinical trials demonstrating that full-body skin examination (FBSE) reduces melanoma morbi

32 at were established in 1972 and repeated the full C inventory by analyzing more than 4 decades of dat

33 ies, with three candidate peptides retaining full cardiovascular activities for potential therapeutic

34 cathode materials, the aqueous Li-ion/sulfur full cell delivers record-high energy densities up to 20

35 The MSNS/LiCoO2 full cell demonstrates high gravimetric energy density i

36 ntion of the lithiated silicon/graphene-SeS2 full cell is 81% after 1,500 cycles at 268 mA gSeS2(-1).

37 use single-cell microscopy to parameterize a full cell-cycle model based on independent control of pr

38 Nevertheless, a full characterisation of this beam has up to now not bee

39 Full chemical analysis of the O-antigens of these strain

40 hat this method can accurately reproduce the full Chl emission spectra - capturing the spectral dynam

41 system has turned into a diffusive collision-full classical system.

42 urring in population subsets rather than the full claustral cell population.

43 o limitations of level of care on ICU day 1 (full code).

44 emporal and inferior parietal regions in the full cohort, with florbetapir positive/negative-associat

45 upported by site-directed mutagenesis allows full comparison with dicot CADs and elucidates the poten

46 egomoviruses and that all clones possessed a full complement of the TrAP gene.

47 purposefully inserted mutations (DNAM2) and full complementary sequence (DNAfull).

48 Lack of full concordance of these datasets has illustrated that

49 ere undetectable using either assay, showing full concordance with the TaqMan assay.

50 complex locomotor actions in the absence of full consciousness.

51 Our findings indicate that, although full control can be theoretically guaranteed by the prev

52 Band-engineering techniques should aim to a full control of the parameter that characterizes the Dir

53 fting from simple control of symptoms toward full control of these diseases (clinical and endoscopic

54 n of reconfigurability, high efficiency, and full control over the phase and amplitude of scattered l

55 essing derivatives of (+)-pleuromutilin with full control over their structure presents an opportunit

56 ategy to obtain regular synthetic cages with full control over their surface properties.

57 ic solvent, whereas in protic solvent almost full conversions were reached.

58 le, and used recombineering to reintegrate a full copy of the gene, generating the {for(BAC)} rescue

59 n's Hospital Colorado, savings justified the full cost of the ASP.

60 rategy may be a valid alternative to routine full-course antibiotic therapy.

61 nature of biological networks suggests that full coverage may not be necessary.

62 resistant cancer cells is a major barrier to full cures.

63 onformational changes that take place in the full CusB protein upon binding Cu(I).

64 e in skull size and body mass throughout the full cycle in wild recaptured shrews (Sorex araneus).

65 The full dataset included information from 909 073 patients,

66 mologist spent 3.7 hours using the EHR for a full day of clinic: 2.1 hours during examinations and 1.

67 Based on a patient with a full deletion of IGSF1 clinically followed from neonate

68 We report herein the full determination of the BH-DVCS interference by exploi

69 tified as a crucial bottleneck, limiting the full development of glycosciences and their considerable

70 n evolution efficiency by 30% and double the full discharge capacity in repeated cycles compared to t

71 Full disclosure was also more common in the Amagugu inte

72 The content of the full document has been changed accordingly, with more ex

73 g patients, either stable mixed chimerism or full donor chimerism were observed.

74 ydrocortisone < 400 mg/day for >/= 3 days at full dose in patients with septic shock that is not resp

75 the sapheno-femoral junction, indication for full-dose anticoagulation therapy, and substantial hepat

76 Using full-dose proton-pump inhibitor and high-dose Metronidaz

77 and high-dose Metronidazole in group A, and full-dose proton-pump inhibitor and prescription from a

78 A pressure-sensor matrix (PSM) with full dynamic range can accurately detect and spatially m

79 As we approach a "Full Earth" of over ten billion people within the next c

80 sensitive rho1 subunits are needed to impart full efficacy to the partial GABA agonists.

81 arch) in Homo was somewhat mosaic, with the full endurance suite apparent only approximately 1 milli

82 tor-triggered secretion from a compound to a full exocytosis mode, in which SGs individually fuse wit

83 sensory neuroscience that has so far evaded full explanation.

84 hem to biochemical pathways is hampering the full exploitation of many metabolomics experiments.

85 always exceed the film thickness, leading to full exponential growth over 3 orders of magnitude thick

86 facilitator but also a prerequisite for the full expression of sensory-evoked NVC responses, indicat

87 A critical step in discovering the full extent of structural variations is the development

88 use and human, but we remain ignorant of the full extent of the genetic landscape involved in auditor

89 beyond operational lease boundaries, yet the full extent of these impacts is unknown and thus neglect

90 The full extent to which childhood pneumococcal conjugate va

91 One variant comprised the full extracellular portion of CD23, including the stalk

92 ollection method and processing framework in full field cryo soft X-ray tomography to computationally

93 w direct PMD (DPMD) method that measures the full-field 3D shape of complicated specular objects.

94 imodal surveillance regimen including yearly full-field digital (FFD) mammography, dynamic contrast a

95 To compare retinal function via full-field electroretinographic (ffERG) recordings in 6.

96 lar function in 17 of 19 subjects and normal full-field retinal function in all subjects.

97 provide a unique solution for a low-speckle, full-field, and coherent imaging in optically scattering

98 carrying DNMs are warranted to delineate the full genetic architecture of rare complex diseases.

99 eries, we have simultaneously determined the full genome of both a novel subtype of HCV genotype 6, a

100 Here, we analyze 563 full genomes, 455 of which are novel, to show that the h

101 bivalent OPV (bOPV) can inform the eventual full global withdrawal of OPV.

102 i-diabetic sulfonylurea drugs to exert their full glucose-lowering effects.

103 but typically unidirectional and minimal in full-grown animals.

104 both with respect to complete remission with full hematologic recovery (34% vs. 16%, P<0.001) and wit

105 d, enables fast and affordable sequencing of full human genomes.

106 combination of M41L + L210W + T215rev showed full human immunodeficiency virus RNA suppression while

107 d be recommended for statin initiation under full implementation of the 2013 ACC/AHA guidelines.

108 currently taking lipid-lowering medication, full implementation of the USPSTF recommendations would

109 ble stabilizing substitutions compromise the full inhibition of contraction in the relaxed state.

110 ng interactions, protein functions, and even full interactome sizes for species with limited to no ex

111 or has several limitations and restricts the full interpretation of biomarker performance.

112 y was to evaluate (18)F-AV-1451 binding with full kinetic analysis using a metabolite-corrected arter

113 Full laser switching is performed by electrostatic gatin

114 emical interrogation of the structure of the full length CTD of Drosophila melanogaster, which we con

115 Here, we report the crystal structures of full length Escherichia coli RapZ at 3.40 A and 3.25 A,

116 Full length rAhAI showed differential inhibition against

117 All peptides, as well as full length Sap6, demonstrated amyloid properties, and a

118 promotes exon 7 inclusion and thus increases full length SMN expression.

119 nstrated that cytoplasmic LANA isoforms were full length, containing the N-terminal nuclear localizat

120 h C3 cyclizing the chain when it reaches the full length.

121 alizes at the tip of filopodia like myosin-X full-length (M10(Full)).

122 Dirichlet process clustering to reconstruct full-length 16S gene sequences from metagenomic sequenci

123 RAMBL first realizes the access to full-length 16S gene sequences in the near-terabase-scal

124 le N-terminally truncated amyloid-beta40 and full-length amyloid-beta40 accumulation showed an almost

125 at N-terminally truncated amyloid-beta42 and full-length amyloid-beta42 accumulations distributed dif

126 iptional activity and protein levels of both full-length and splice-variant AR.

127 ariable efficiencies to control synthesis of full-length and truncated SELENOP isoforms.

128 n G (IgG) were fabricated using well-defined full-length antibody-polymer conjugates (APCs).

129 apid cell-death induction in vivo requires a full-length ASC.

130 report that BH3-only proteins bind inactive full-length BAK at mitochondria and then dissociate foll

131 Transfection of cells with full-length CaM slightly increased the ability of estrog

132 rapid amplification of cDNA ends (RACE) and full-length cDNA sequencing, revealed four independent p

133 on, NMR, and small-angle x-ray scattering on full-length ColN and its fragments.

134 ritical for relieving the auto-inhibition of full-length Drs2p, whereas the 1-104 N-terminal residues

135 65kDa truncated protein isoform that opposes full-length eIF2Bepsilon to inhibit global translation.

136 were derived from 128 667 intron-containing full-length FLNC reads, including a large number of AS e

137 present, one being a cleavage product of the full-length form.

138 hese mutations reduced surface expression of full-length G1 but not G1-DeltaNT in HEK-293 cells.

139 is anticorrelated with the expression of the full-length GAD1 transcript.

140 CA45, while exhibiting negligible binding to full-length GP, bound a proteolytically remodeled GP wit

141 rms, we overexpressed and purified the three full-length human isoforms from suspension-adapted HEK c

142 ntroduction of equivalent stop codons in the full-length human L1 sequence leads to the expression of

143 Here we present two structures of full-length human TRPM4 embedded in lipid nanodiscs at

144 Plants constitutively expressing full-length HWS-but not a truncated version lacking the

145 Perivascular access and distribution of full-length IgG could be enhanced by intrathecal co-infu

146 2 can selectively bind evolutionarily young, full-length L1s located within transcriptionally permiss

147 dies on a pathogenic mutation that generates full-length M1 and M87 proteins, truncated M1 was notabl

148 Without these shorter isoforms, full-length MAVS is prone to spontaneous aggregation and

149 bstitutions, which lead to the expression of full-length mutant proteins that accumulate in cancer ce

150 we perform electrophysiological analysis of full-length NMDARs with a glycosylation-preventing GluN1

151 In total, 145 522 mapped full-length non-chimeric (FLNC) reads were analyzed, res

152 Full structural characterization of the full-length oligomeric p53 is challenging because of its

153 s African trypanosomiasis and contains three full-length oligosaccharyltransferase (OST) genes; two o

154 ressed in Arabidopsis, the overexpression of full-length OsbZIP48 in rice transgenics reduced the pla

155 507) phosphorylation (that does not apply to full-length PKCdelta) in structurally organizing diverse

156 Here, we expressed and purified full-length porcine INSL3 (pINSL3) using a silkworm-base

157 cated form of this enzyme suggested that the full-length protein was required for correct lipid subst

158 ion of the affected gene and production of a full-length protein.

159 foundation for understanding recognition of full-length proteins by HDACs.

160 ificant expression originating from 15 HML-2 full-length proviruses, through four modes of transcript

161 on of the PTEN C2 domain mimicked effects of full-length PTEN but a membrane-binding defective mutant

162 l isoforms based on the number of supporting full-length reads with those of annotated isoforms and e

163 ation, an endpoint robustly activated by the full-length receptor.

164 high resolution in Saccharomyces cerevisiae Full-length resection requires Exo1 exonuclease and the

165 Two distinct nearly full-length Rhizobiales genomes were identified in leaf-

166 esulting synthetic nucleocapsids package one full-length RNA genome for every 11 icosahedral assembli

167 However, the vector expressing full-length RSV F from the pre-N position was immunogeni

168 Two RNAs were studied: the full-length segment 5 (+)RNA and a shorter construct con

169 7S has SUMO isopeptidase activity but unlike full-length SENP7L, SENP7S is localized in the cytosol.

170 igand ectodysplasin A (EDA) is produced as 2 full-length splice variants, EDA1 and EDA2, that bind to

171 ntain and transmit [SWI(+)] independently of full-length Swi1.

172 e pseudoknot does not form in the context of full-length TER in the absence of TERT, due to formation

173 Gene annotations were updated using 111,000 full-length transcripts obtained by single-molecule real

174 , number of chimeras and number of recovered full-length transcripts.

175 est in gene coverage and number of recovered full-length transcripts.

176 Full-length uPAR is released from the cell surface, but

177 Increasing full-length viral RNA abundance or distribution had litt

178 in trans In contrast, artificially tethering full-length viral RNAs or surrogate gag-pol mRNAs compet

179 more than three orders of magnitude for the full-length wild-type KcsA, a pH-gated bacterial channel

180 rt the cryo-electron microscopy structure of full-length ZntB from Escherichia coli together with the

181 tely 23- to 24-kDa protein diminish, and the full-length, approximately 45-kDa K15P protein accumulat

182 ases of the Clk family control the supply of full-length, functional mRNAs coding for a variety of pr

183 ng the scope, accuracy, and dynamic range of full-lipidome quantitative shotgun profiling.

184 Furthermore, by tracing the full lithiation procedure, the evolution of the MnO inte

185 L, reflecting the importance of implementing full LSL replacement and efficient risk communication.

186 igher than those released from the simulated full LSL.

187 those with MSI < 0.50 and we would advocate full LV coverage in future studies.

188 Full LV coverage T1 and T2 mapping are more accurate tha

189 r differentiation and susceptibility for the full lytic cycle of HCMV.

190 M10(Full)LZ localizes at the tip of filopodia like myosin-X

191 Herein we theoretically investigate the full many-body dynamics of the acquisition of angular mo

192 On the other hand, full mapping of the magnetic field has hitherto remained

193 While few participants completed the full MenB vaccination series, limiting analytic power, t

194 We found that apelin-36(L28A) retains full metabolic activity, but is 100-fold impaired in its

195 Archaea were not directly involved in full methane oxidation, but their crucial participation,

196 Here, we report the recovery of full mitochondrial genomes from four and partial nuclear

197 is inhibited by tetherin and is required for full MoMLV pathogenesis.IMPORTANCE Retroviruses are thou

198 ere calculated using a 15% cut-off point: 1) full-mouth (MB-B-DB/MB-B-DL); 2) two diagonal quadrants

199 pants (adolescents aged 15 to 17 years), and full-mouth clinical parameters of oral health were asses

200 GB was determined by full-mouth examination (FME) of six sites (disto-buccal

201 Full-mouth periodontal examinations were performed, and

202 values, retention times, isotopic patterns, full MS, and MS/MS spectra.

203 Obtaining the full MS/MS map for fragments and precursors of complex m

204 ic resonance (MR) imaging in comparison with full multiparametric contrast material-enhanced prostate

205 S) version 2; only thereafter, the remaining full multiparametric contrast-enhanced MR images were re

206 years) first reviewed only a fraction of the full multiparametric contrast-enhanced MR images, consis

207 cancer detection rate of biparametric versus full multiparametric contrast-enhanced MR imaging and be

208 that are equivalent to those of conventional full multiparametric contrast-enhanced MR imaging protoc

209 Individuals with an FMR1 full mutation were randomized to placebo or one of two d

210 s showed significantly greater likelihood of full neurological recovery (mRS 0-1) at day 90 (OR 7.6,

211 uggest that CK2 inhibitors could release the full neuroprotective potential of HSJ1, and deserve futu

212 n multiple EGF repeats and are essential for full Notch function.

213 t visible; 1, moderate opacification; and 2, full opacification.

214 Longitudinal clinical evaluation, including full ophthalmic examination, multimodal retinal imaging,

215 excellent KOP receptor selectivity acting as full or partial agonists, and one as an antagonist.

216 and dry mouth and is classified as either a full or partial muscarinic agonist.

217 B2R reference ligands, spanning the range of full, partial, and inverse agonists.

218 and with respect to complete remission with full, partial, or incomplete hematologic recovery (44% v

219 ive growth trends of 1-2% per decade for the full period, and 3-7% since 1950.

220 We experimentally determined the full phase diagram of an IgG antibody.

221 chanical dormancy is conferred by preventing full phase-II water uptake of the encased non-dormant se

222 variance-reduced Monte Carlo method with the full phonon dispersion and intrinsic lifetimes from firs

223 evaluated through balance checks within the full population, and they are usually assessed through p

224 We demonstrated that the transition from full potency to lineage priming is prevented by inhibiti

225 mass spectrometry (GCIB-SIMS) has shown the full potential of mapping intact lipids in biological sy

226 inning the knowledge required to realize the full potential of plasma in biology and medicine.

227 , mechanical withdrawal threshold revealed a full preventive action against transient mechanical hype

228 ontact activation and is responsible for the full procoagulant activity of FXII.

229 Full protection provided stronger effects than partial p

230 Additionally, the ability to obtain full PV genomes from FTA cards will aid in facilitating

231 ecessary, but not sufficient, to improve the full range of medical outcomes in this vulnerable popula

232 Comparing these structures illustrates the full range of motion of the activation gate, from closed

233 matics methods have been used to address the full range of questions studied by agricultural entomolo

234 markably high, with 15 cases (83%) reporting full recovery and 3 cases ending in death.

235 This loss greatly affects full recovery of motor function.

236 Unexpectedly, we show that a full reduction in eIF3j affinity for the 43S PIC require

237 gf8 and Bmp4 Histological analyses indicated full regrowth of digit tips in the Msx-overexpressing gr

238 As the global community prepares for the full removal of all OPV from immunization programs, this

239 around S1 segments of proximal tubules, and full renal protection required both macrophages and rena

240 ath application of a KOR antagonist provides full rescue of both LTP induction and dopamine release d

241 We compiled the full rosters of invited speakers over the last 35 years

242 Overall, 65 936 of the full sample died during follow-up, and 22 152 died from

243 greatest shifts in the osmotic potential at full saturation and the turgor loss point.

244 atomic structure determination, to cover the full scale of cellular processes.

245 ation is shown to agree remarkably well with full-scale air-refractivity calculations involving over

246 objective of this study was to build several full-scale biosand filters (BSFs) and assess the long-te

247 A full-scale purification of oligomeric proanthocyanidins

248 h a system was implemented successfully in a full-scale wastewater treatment plant.

249 Full scan field asymmetric waveform ion mobility spectro

250 ass spectrometry (APCI-qTOF-MS), operated in full scan negative ion mode.

251 licate citations were screened, 32 underwent full screening and data extraction, and 14 trials were e

252 Full separation of GVL activity from GVHD has yet to be

253 e protection, but not to the same level as a full series.

254 Full-sibling pairs exhibited significantly greater (13)

255 databases, we used a corelative design with full siblings alongside a general Swedish population sam

256 We evaluated the full size distribution (from 0 to 100 mum in aerodynamic

257 estimated well-to-wheels GHG emissions from full-size BEVs with 100-mile range are 62 gCO2-e mi(-1)

258 e 62 gCO2-e mi(-1) in 2050, while those from full-size ICEVs are 121 gCO2-e mi(-1).

259 gly, some changes enhanced the production of full-size transcripts by suppressing abortive loss of sh

260 e robust model systems that recapitulate the full span of thymopoiesis, from hematopoietic stem and p

261 Despite recent progress, the full spectrum of consequences as a result of KCNQ2 dysfu

262 e data provide a clear, unbiased view of the full spectrum of genes regulated by NPAS1 and NPAS3 and

263 dult height with healthy aging measured by a full spectrum of health outcomes, including incidence of

264 lter the physical properties of DNA, but the full spectrum of the evoked changes is unknown.

265 This method enables, for the first time, the full spectrum of transcriptome data to be obtained from

266 Full structural characterization of the full-length olig

267 We show that TMEM97 possesses the full suite of molecular properties that define the sigma

268 "post burn-in" efficiency over 3400 h under full sun illumination in ambient conditions.

269 Around 20-30% retain the full syndrome as young adults, and about 50% show partia

270 ctivity and NFAT translocation, a measure of full T-cell activation.

271 to -0.59) lower compared with those born at full term.

272 maternal BMI and rates of cerebral palsy in full-term children was mediated through asphyxia-related

273 e dramatically different from those in which full-term infants mature and thus likely impact the deve

274 that differentiate them from sham stimuli in full-term infants.

275 Full-term pups developed in room air (RA) or an oxygen-i

276 tant step towards accurate prediction of the full tertiary structure.

277 closer screening of the abstracts and 93 for full text evaluation.

278 r further evaluation after abstracts and the full text of eligible articles were screened.

279 endently screened titles and abstracts, read full-text articles, and extracted data.

280 igators independently reviewed abstracts and full-text articles, then extracted data from fair- and g

281 73 abstracts reviewed, 131 were selected for full-text review, and 29 met the inclusion criteria, rep

282 d abstract screening and 181 articles during full-text screening.

283 igators independently conducted abstract and full-text screenings, data extractions, and risk of bias

284 ized fashion including exchange of a disc of full-thickness recipient cornea (up to the DSAEK stromal

285 rgical excision of the nail unit followed by full-thickness skin graft reconstruction from January 1,

286 hloride content of SSA particles ranged from full to partial depletion, with 24% of SSA particles con

287 monstrate that SET1A/COMPASS is required for full transcriptional activation of multiple Hox genes bu

288 e contribution of each taxon topology to the full tree.

289 g the basic principles in order to develop a full understanding about piezotronics and it also enable

290 ntify key issues that require resolution for full understanding of pathogenic autoimmunity.

291 Full understanding of the processes leading to loss of e

292 all strategies (routine patient discharges, full use of staffed and unstaffed licensed beds, and can

293 ext is becoming increasingly crucial to make full use of the data.

294 ent studies have not fully accounted for the full variability in the crude oil transport stage, for e

295 tions in Avr2 (e.g. Avr2(R45H) ), but retain full virulence.

296 Using 3D full-waveform tomography, we reveal an expansive low-vel

297 Full width at half-maximum analysis (fwhm) was performed

298 mtosecond soliton pulses were generated with full width half maxima of 417 fs for DNA and 323 fs for

299 of 54 +/- 5 ms corresponding to an estimated full-width of only 1 m degrees C.

300 be needed for a thorough, synchronized, and full withdrawal of OPV, and such preparation would be ai