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1 memory B cells as well as the production of fully human antibodies.
3 b phage display library, we have generated a fully human antibody (A12) that binds to the IGF-IR with
4 effective and safe immunotherapeutic drugs, fully-human antibodies affinity-matured in a healthy hos
6 antibodies (that are rapidly convertible to fully human antibodies) and have fully functional humora
8 hesis clinically, we developed (89)Zr-5B1, a fully human, antibody-based radiotracer targeting tumor-
9 latory approval of panitumumab (Vectibix), a fully human antibody directed against epidermal growth f
12 onoclonal antibodies, allowing the design of fully human antibodies of any specificity and for divers
13 immunoglobulin G1 Fc region to construct the fully human antibody scFv-FcC21, which recognized tumors
18 nomics and with methods now in place to make fully human antibodies, the potential of antibodies as v
19 ional engineering methodology for generating fully human antibody therapeutics from murine mAbs produ
20 n enables the mice to generate high affinity fully human antibodies to multiple antigens, including h
21 een used to generate numerous high-affinity, fully human antibodies to targets in multiple disease in
22 14 patients with metastatic melanoma using a fully human antibody to cytotoxic T-lymphocyte antigen-4
24 mor necrosis factor alpha, we have generated fully human antibodies with 59, 46, and 45 substitutions
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