ライフサイエンスコーパス: functional capacity

1 y give rise to neural progeny with different functional capacity.

2 h once referred, gain significant benefit in functional capacity.

3 e roles throughout biology and exhibit broad functional capacity.

4 *009 surface expression, binding to HLA, and functional capacity.

5 nd endurance are other important elements of functional capacity.

6 t poor self-rated health as well as impaired functional capacity.

7 gardless of cause, demonstrate a compromised functional capacity.

8 a central, but not complete, determinant of functional capacity.

9 ompromised and contributes to the decline in functional capacity.

10 rtion of life living with dystonia and lower functional capacity.

11 however, neither metabolite correlated with functional capacity.

12 y suppressive phenotype and had an increased functional capacity.

13 ST2 was modestly associated with measures of functional capacity.

14 greater improvements in muscle strength and functional capacity.

15 xygen delivery and, hence, improve patients' functional capacity.

16 unfavorable effect was associated with worse functional capacity.

17 and CD8 coreceptors had little effect on its functional capacity.

18 on targets for manipulating the microbiome's functional capacity.

19 renewal and expansion of HSCs with long-term functional capacity.

20 cating that these mutants maintain intrinsic functional capacity.

21 l effects on left ventricular remodeling and functional capacity.

22 ree-dimensional architecture greatly impacts functional capacity.

23 nd whether the remaining DC subsets maintain functional capacity.

24 uccumb to apoptosis once they have exhausted functional capacity.

25 n with cognate peptide, thus enhancing their functional capacity.

26 mposition of the bacterial community and its functional capacity.

27 (MRI) and spectroscopic (MRS) correlates of functional capacity.

28 of adverse events, the quality of life, and functional capacity.

29 gnificantly improved the quality of life and functional capacity.

30 in the child's level of activity and overall functional capacity.

31 ially due to the effect of such variation on functional capacity.

32 d cells are typically immature with impaired functional capacity.

33 iated with improvements in health status and functional capacity.

34 and progressive tissue fibrosis with loss of functional capacity.

35 oliferation; and innate cellular subsets and functional capacity.

36 ests of working memory, processing speed and functional capacity.

37 idea for a new classification based on this functional capacity.

38 tely portray microbial communities and their functional capacities.

39 embryonic Ag-reactive T cells with different functional capacities.

40 elop similar effector cytokine and cytolytic functional capacities.

41 supportive approach with no such emphasis on functional capacities.

42 enewal capacity, and display additional AEC2 functional capacities.

43 ent in preschool-age children with CP across functional capacities.

44 ead to altered target cell specificities and functional capacities.

45 but not significantly different measures of functional capacity (12.9 [0.3] vs 13.0 [0.2]; P = .23).

46 an indicator of disease pathology, and total functional capacity, a widely-used clinical measure of d

47 At the same time, disruption of the rafts' functional capacity, achieved by the pathogens through a

48 impart substantial morbidity and compromised functional capacity after lung transplantation.

49 The HBAI permits assessment of global functional capacity allowing the rational choice of opti

50 ortance and are insensitive to difference in functional capacity among individuals who do not experie

51 ning benefits translate to an improvement in functional capacity and an enhanced ability to perform a

52 The functional capacity and antifungal activity of these cel

53 of patients with biopsy-proven ATTRwt, poor functional capacity and atrial arrhythmias were common c

54 ith measures of clinical efficacy, including functional capacity and clinical status, analysed per pr

55 ailure (HF) progression results in worsening functional capacity and end-organ compromise.

56 ated with a clinically relevant reduction in functional capacity and health status.

57 sults in clinically relevant improvements in functional capacity and heart failure-related quality of

58 w left ventricular assist devices (LVADs) on functional capacity and heart failure-related quality of

59 gut microbiomes with surprising parallels in functional capacity and higher level taxonomy to those o

60 ing the mitral valve during CABG may improve functional capacity and left ventricular reverse remodel

61 luated ST2 levels and their association with functional capacity and long-term clinical outcomes in a

62 ) and is an independent predictor of reduced functional capacity and mortality.

63 failure patients and is associated with poor functional capacity and other known measures of heart fa

64 ne the need for greater understanding of the functional capacity and phylogenetic affiliation of nove

65 ventricular (RV) functional reserve affects functional capacity and prognosis in patients with pulmo

66 his is the first study to prove an increased functional capacity and quality of life after transapica

67 Functional capacity and quality of life improved markedl

68 erm moderate exercise training (ET) improves functional capacity and quality of life in New York Hear

69 known to be an effective means of improving functional capacity and quality of life in patients with

70 rove other patient-centric concerns, such as functional capacity and quality of life.

71 isease, with additional benefits of improved functional capacity and reduced falls.

72 hich SAH was induced exhibited reduced acute functional capacity and reduced general activity to 1 mo

73 nts who reported persistent fatigue, lowered functional capacity and sickness leave or delayed educat

74 , but adaptive RVH is associated with better functional capacity and survival.

75 ient to restore damaged myocardium to normal functional capacity and that cellular cardiomyoplasty is

76 h HFpEF have significant impairment in their functional capacity and their quality of life on a daily

77 measures were predictive of decline in total functional capacity and tracked longitudinal change; als

78 le from embryonic stem cells (ESCs) in their functional capacity and transcriptome and DNA methylatio

79 tandardization Study (PASS), two measures of functional capacity and two interview-based measures of

80 ST2 was modestly associated with functional capacity and was significantly associated wit

81 e Appropriate only for patients who had poor functional capacity and were undergoing vascular or inte

82 marked abnormalities in muscle mitochondrial functional capacity and when severe, these alterations c

83 acyl chain compositions should have distinct functional capacities, and cardiolipin that has been rem

84 iabetes, hypertension, hyperlipidemia, lower functional capacity, and a lower Duke Treadmill Score.

85 xpression of inhibitory receptors, decreased functional capacity, and a skewed transcriptional profil

86 PPVI has the potential to improve symptoms, functional capacity, and biventricular hemodynamics.

87 suggests that parathyroidectomy can improve functional capacity, and hence the performance of ADLs i

88 tent AF and HF, and can improve LV function, functional capacity, and HF symptoms compared with rate

89 We compared in-hospital morbidity, functional capacity, and long-term outcomes of patients

90 e used to assess the relationship among ST2, functional capacity, and long-term outcomes.

91 determine CD4+ T cell (TCD4+) specificities, functional capacity, and memory persistence in response

92 cells during ART, we assessed the frequency, functional capacity, and memory profile of CD4(+) T cell

93 systolic function on the clinical features, functional capacity, and outcomes of this population is

94 eart failure and anemia have worse symptoms, functional capacity, and outcomes than those without ane

95 showed significant improvements in survival, functional capacity, and quality of life.

96 providing meaningful increases in survival, functional capacity, and quality of life.

97 onia, with increases in neutrophil motility, functional capacity, and survival.

98 and that exosome secretion, composition, and functional capacity are altered as tumors progress to an

99 suggest that the community may be reduced in functional capacity as estimated by KEGG pathways.

100 nd (2) study the association between PAD and functional capacity as well as health status.

101 ry disease causes a significant reduction in functional capacity because of dyspnea and fatigue, part

102 th Doppler indices of diastolic dysfunction, functional capacity, biomarkers, invasive hemodynamics,

103 nction are responsible for not only impaired functional capacity but also lethal ventricular arrhythm

104 rterial blood pressure x cardiac output) and functional capacity by peak exercise O2 consumption.

105 ed to assess the potential of improving hCPC functional capacity by targeting the P2Y14 purinergic re

106 Whether these extensive functional capacities can be attributed to a single popu

107 ich has implications for the degree to which functional capacity can be improved.

108 rts, we show that shifts in the microbiome's functional capacity can be traced back to specific taxa.

109 a such as hospitalization for HFpEF, altered functional capacity, cardiac structural and functional a

110 how marine metagenome and metatranscriptome functional capacity changes across seasons.

111 eporting poor self-rated health and impaired functional capacity compared to individuals not experien

112 eporting poor self-rated health and impaired functional capacity compared to respondents with symptom

113 between regional cortical thinning and total functional capacity, currently the leading primary outco

114 Total functional capacity declined by 0.6 point per year (95%

115 IV activity suggests that they retain their functional capacity despite this morphological change.

116 (Hospital Anxiety and Depression Scale), and functional capacity (Duke Activity Status Index).

117 ese data suggest that human cortex has broad functional capacity during development, and input plays

118 ry protocol can achieve cardiac and physical functional capacities equivalent to those of healthy con

119 tates toward facilitating their adaptive and functional capacities, even as species ebb and flow indi

120 and PD-1(+)TIGIT(-) CD8(+) TILs had similar functional capacities ex vivo, suggesting that TIGIT alo

121 izophrenia have separated the measurement of functional capacity from real-world functional outcomes.

122 Muscle force and functional capacity generally decrease with aging in the

123 Visual acuity, vision-related function, functional capacity, harms, and diagnostic accuracy.

124 a community does not necessarily predict its functional capacities; however, characterizing specific

125 Due to their versatile functional capacities, human CD40L(+) CD8(+) T cells are

126 The quality of life and functional capacity improved significantly in both group

127 Quality of life and functional capacity improved to a similar degree in the

128 ality among the oldest-old, but that women's functional capacities in activities of daily living, cog

129 dent lymphocyte population, possessing multi-functional capacities in the repair of host tissue, path

130 udy to show that FNDC5 expression relates to functional capacity in a human HF population.

131 general self-rated health and self-reported functional capacity in adults meeting the criteria for G

132 D25 to isolate T(reg) cells and assess their functional capacity in an ongoing adaptive immune respon

133 ications for improving muscle energetics and functional capacity in hypoxia.

134 Investigating interventions to improve functional capacity in ICU survivors will require strati

135 exercise, and the implications this has for functional capacity in older adults.

136 of underlying rhythm on quality of life and functional capacity in patients with atrial fibrillation

137 their ability to account for differences in functional capacity in patients with focal unilateral me

138 o exercise training as a means of optimizing functional capacity in patients with heart failure.

139 appears to be a promising therapy to improve functional capacity in patients with HF.

140 ion of L-arginine on vascular reactivity and functional capacity in patients with PAD.

141 response effect of task-specific training on functional capacity in people with long-standing upper-l

142 lementation improves vascular reactivity and functional capacity in peripheral arterial disease (PAD)

143 ations can restore mitochondrial content and functional capacity in skeletal muscle in type 2 diabeti

144 risk of cardiovascular disease and impaired functional capacity in the elderly.

145 nostic significance of exercise behavior and functional capacity in this population.

146 tic stem cells (HSCs), measured by decreased functional capacity in transplantation assays, preferent

147 The largest differences were noted for functional capacity, in which etanercept fared worse tha

148 Functional capacity is a broad term that describes a per

149 Impaired functional capacity is a hallmark of patients with heart

150 Functional capacity is a key metric in this population,

151 Functional capacity is a robust predictor of clinical ou

152 Functional capacity is an important predictor of postope

153 P2X(7) functional capacity is associated with asthma risk or di

154 Functional capacity is commonly impaired after critical

155 This reduced energetic and functional capacity is consistent with a known susceptib

156 The impact on self-rated health and functional capacity is highest among individuals experie

157 The 5-HT2CR functional capacity is regulated by a number of factors

158 tients with moderate ischemic MR may improve functional capacity, left ventricular reverse remodeling

159 ationship between microbiome composition and functional capacity, linking metagenome-level compositio

160 tations) or infant factors (e.g. reduced CTL functional capacity) may explain this observation.

161 Impaired functional capacity (mean Vo2max, 13.5 mL.kg(-1).min(-1)

162 hormones, as well as noninvasive imaging and functional capacity measurements.

163 across the various criteria, except that the functional capacity measures had stronger relationships

164 related to performance on neurocognitive and functional capacity measures.

165 ion, endothelial progenitor cell numbers and functional capacity, metabolic parameters, and disease a

166 r LVAD can even achieve cardiac and physical functional capacities nearly equivalent to those of heal

167 To test the functional capacities of (64)Cu-OVA-Th1 cells during exp

168 memory B cells but also pointed at distinct functional capacities of both subsets.

169 The functional capacities of CD8(+) T cells important for vi

170 ry T cells (Tmem), little is known about the functional capacities of chronically stimulated but prot

171 503 (antisense oligonucleotide) improved the functional capacities of ECs cultured under high D-gluco

172 (i.e., geochip 4.2) was used to analyze the functional capacities of soil microbial communities coll

173 guity of CD4/CD8 expression in dictating the functional capacities of T cells and suggest that accumu

174 T cell responses, and suggest that long-term functional capacities of T cells are set by innate signa

175 We observed that the functional capacities of T cells induced by VACV and ECT

176 As a consequence, the functional capacities of the TCR, the low-affinity Fc re

177 and illustrate a key difference between the functional capacities of the two AURK homologues.

178 l and biophysical data that characterize the functional capacities of these mutant myosins suggests t

179 tation (c.1073 G>A, p.C358Y) with a residual functional capacity of 48% of wild-type protein.

180 The functional capacity of a battery is observed to decrease

181 ences is an important step for assessing the functional capacity of a metagenome.

182 Herein, we evaluate the functional capacity of a prevascularized subcutaneous si

183 scriptional factor Eomesodermin and enhanced functional capacity of Ag-specific T cells of M. tubercu

184 sufficient to enhance the magnitude and the functional capacity of antigen-specific effector and mem

185 une evasion potential of NS1 in reducing the functional capacity of C4 in complement activation and c

186 To determine the functional capacity of CD4 T cells generated by chronic

187 -CSF is also required to determine the basal functional capacity of circulating neutrophils, includin

188 s that IFN-alpha differentially improves the functional capacity of classic myeloid dendritic cells (

189 th our prior observation of enhanced ex vivo functional capacity of CSF T cells.

190 erved in the skin (shingles), the number and functional capacity of cutaneous VZV-specific T cells ha

191 e retained in the mother cell to protect the functional capacity of daughter cells, the fate of ER pr

192 uppression assay was performed to assess the functional capacity of derived T-cell clones.

193 e large reduction in protein expression, the functional capacity of dystrophin proteins deleted for s

194 signaling influence the differentiation and functional capacity of effector and memory CD8(+) T cell

195 kade of IL-10 enhanced the magnitude and the functional capacity of effector CD4 T cells that transla

196 LDG depletion restores the functional capacity of endothelial progenitor cells.

197 e indicates that secretion, composition, and functional capacity of exosomes are altered as tumors pr

198 ve splicing (AS) increases the proteomic and functional capacity of genomes through the generation of

199 d individuals, we examined the frequency and functional capacity of HIV-1-specific T cells.

200 oviding a potential target for enhancing the functional capacity of HIV-specific CD4(+) T cells.

201 t within, pairs and correlated with in vitro functional capacity of islets as assessed by perifusion

202 Pimecrolimus also increased the functional capacity of keratinocytes to inhibit growth o

203 beta promotes significant improvement in the functional capacity of lupus EPCs/CACs, therefore abroga

204 , we evaluated the frequency, phenotype, and functional capacity of M. tuberculosis-specific CD4 T ce

205 we determined the frequency, phenotype, and functional capacity of MAIT cells in colon adenocarcinom

206 To investigate the functional capacity of mature granulocytes from Gc-treat

207 erformed twice weekly for 10 years maintains functional capacity of more than 60% of maximum Vo(2) an

208 n, donor pathology of MSCs can influence the functional capacity of MSCs.

209 itative reduction, rather than a decrease in functional capacity of mutant enzyme.

210 f sEAE correlates with a decline in both the functional capacity of natural regulatory T cells (nTreg

211 The functional capacity of NK cells is dynamically tuned by

212 e frequency, absolute number, phenotype, and functional capacity of NK cells was monitored in 191 ind

213 ever, little evidence is available about the functional capacity of normal human melanocytes, maligna

214 urposes of this study were 1) to compare the functional capacity of pDCs in patients with one type of

215 ttributable to a reduction in the number and functional capacity of PDK1-deficient T regulatory (Treg

216 equencing and activity assays to examine the functional capacity of permafrost soils and cryptoendoli

217 Thus, the average health and functional capacity of persons age 65+ must improve for

218 Taken together, these data demonstrate the functional capacity of pkaC2 and emphasize the importanc

219 The functional capacity of specific IgE antibodies was asses

220 prepubescent primates can maintain the fully functional capacity of spermatogonia to produce sperm, b

221 o play a significant role in maintaining the functional capacity of stem cells and may provide furthe

222 Functional capacity of T cells, assessed by production o

223 In this study, we assessed the functional capacity of T(regs) lacking the ability to se

224 We hypothesized that the functional capacity of the 5-HT2AR, which is governed by

225 ing actin filament and therefore specify the functional capacity of the actin filaments that they cre

226 The functional capacity of the adaptive immune system is dep

227 Studies have described the structure and functional capacity of the bacterial microbiome in the h

228 Species-specific differences in the functional capacity of the CD4 receptor to mediate entry

229 sponse (UPR) signaling pathway regulates the functional capacity of the endoplasmic reticulum for pro

230 ementation on the phylogenetic structure and functional capacity of the fecal microbiome of healthy a

231 However, the composition and functional capacity of the gut microbiome in relation to

232 toperative working memory was reliant on the functional capacity of the hippocampal remnant and, foll

233 Our results indicate that the functional capacity of the hippocampus is shaped by its

234 n found to alter the taxonomic, genomic, and functional capacity of the human gut microbiota, with ef

235 ion of memory CD4+ T cells and a loss of the functional capacity of the memory CD4+ T lymphocytes tha

236 ted these interactions resulted in a reduced functional capacity of the MFEzeta CAR to respond to car

237 lection of data describing the structure and functional capacity of the microbiome in a variety of co

238 and maintaining normal size, complexity and functional capacity of the neuromuscular synapse.

239 Additionally, neither the magnitude nor the functional capacity of the SIV-specific T-cell-mediated

240 sions known as microvilli that increases the functional capacity of the tissue.

241 and that this mechanism strongly impacts the functional capacity of the vasoconstrictor angiotensin I

242 chronic infections, no obvious defect in the functional capacity of the viral-specific CD8(+) T cell

243 Little is known about the functional capacity of these lymphocytes, which could pr

244 However, the functional capacity of these responses in 12-month-old i

245 at the sumoylation cycle greatly expands the functional capacity of transcription factors such as SF-

246 Systematic evaluation of the functional capacity of tumor-associated stromal cells re

247 he neuromuscular system (muscle strength and functional capacity) of older women.

248 th regard to both magnitude of expansion and functional capacity on a per-cell basis, which also corr

249 reviews the essential physiology underlying functional capacity on systemic, organ, and cellular lev

250 bstructive pulmonary disease did not improve functional capacity or quality of life.

251 There was no change in functional capacity or symptoms between the two groups a

252 memory but not processing speed performance, functional capacity, or positive or negative symptom sev

253 fference in invasive pulmonary hemodynamics, functional capacity, or symptoms between the bosentan an

254 predicted by younger age (P<0.0001), poorer functional capacity (P=0.016), having an ICD shock (P=0.

255 g to elucidate the microbial composition and functional capacity present in the human microbiome has

256 Pre-operative testing for patients with good functional capacity, prior normal testing within 1 year,

257 ormalities were associated with this loss of functional capacity (problem behaviours assessment compo

258 We assessed motor functional capacity, quadriceps size, strength, and volu

259 te, MSC injection favorably affected patient functional capacity, quality of life, and ventricular re

260 uated outcomes included response, remission, functional capacity, quality of life, reduction of suici

261 roop word reading r=-0.248, p=0.0033), total functional capacity (r=-0.289, p=0.0264), and brain atro

262 changes except Stroop word reading and total functional capacity remained significant after adjustmen

263 to an earlier developmental stage, but their functional capacity remains ill defined.

264 sease Questionnaire and summary index, Total Functional Capacity scale, and the 12-item Short Form He

265 sures activities of daily living); the Total Functional Capacity scale; the 39-item Parkinson's Disea

266 early HD (classed as HD1 if they had a total functional capacity score of 11-13 and HD2 if they had a

267 behavioral symptoms), and functional (Total Functional Capacity score range, 0-13; lower scores indi

268 ion were inversely correlated with the Total Functional Capacity score, but with apathy showing the s

269 6-0.18) in the rate of change of UHDRS Total Functional Capacity score.

270 d HFrEF patients, with objective measures of functional capacity similar to HFpEF.

271 postulated that a more objective measure of functional capacity, such as 6-min walk (6MW) distance,

272 isease Rating Scale total motor score, total functional capacity, symbol digit modalities test, and S

273 worsening total motor score (TMS) and total functional capacity (TFC).

274 a large number of interneurons with similar functional capacity that are distributed into different

275 obvious potential for the rehabilitation of functional capacity that has been lost through brain ins

276 s) differ from their younger counterparts in functional capacity, the complement of proteins on the c

277 time of hospitalization, but they recovered functional capacity to control levels during the convale

278 ding sites, Notch proteins have linked their functional capacity to developmentally regulated biosynt

279 A quantitative assessment of their functional capacity to differentiate between these two m

280 MSCs derived from ANXA1(-/-) mice had no functional capacity to enhance GSIS, in contrast to wild

281 The spleen regulatory B cell subset with the functional capacity to express IL-10 (B10 cells) modulat

282 l maturation, suggesting that vSMCs have the functional capacity to influence blood vessel formation

283 absence of Nlrp3 did not alter either their functional capacity to inhibit T cells or their presence

284 ighlighting that fibrinogen(AEK) retains the functional capacity to support interactions with platele

285 ults demonstrate that PTPsigma regulates HSC functional capacity via RAC1 inhibition and suggest that

286 adherence) and clinical outcome indicators (functional capacity (VO(2peak)), anthropometrics) of CR

287 defined as IL-17a(+) CD4 T cells, and their functional capacity was assessed by the coproduction of

288 Functional capacity was measured by 6-min walk distance

289 Self-rated health and functional capacity was measured by single global questi

290 Functional capacity was not an independent predictor of

291 ment did not affect Treg stability; however, functional capacity was reduced.

292 In support of their functional capacity, we observed that BET, in combinatio

293 Muscle strength and functional capacity were assessed before and after the t

294 Improvements in quality of life and functional capacity were similar in patients with AF and

295 tinuum with overestimation or 'polishing' of functional capacity, which appears to be more directly m

296 d with hemodialysis develop severely reduced functional capacity, which can be partially ameliorated

297 IL-10(-/-) mast cells had reduced functional capacity, which could be restored by exogenou

298 n of long-lived memory T cells with superior functional capacity, with potential use in adoptive T-ce

299 ncreased the proportion of CD8+ T cells with functional capacity within the cancerous gland.

300 right ventricular hypertrophy and improving functional capacity without affecting systemic hemodynam