ライフサイエンスコーパス: functional characterization of

1 Functional characterization of 1 novel variant, E141G-Ca

2 Toward the functional characterization of 14-3-3epsilon and 14-3-3s

3 Here we present a functional characterization of 2.5 A and 3.25 A X-ray cr

4 synthesis, via native chemical ligation, and functional characterization of (24-108)MDMX and its Tyr9

5 Functional characterization of 27 site-directed mutants

6 We describe the structural and functional characterization of a 237 residue deacetylase

7 We report the functional characterization of a conserved proteasomal r

8 The functional characterization of a cyclin whose transcript

9 Here, we report the identification and functional characterization of a cytochrome P450 gene in

10 inding provides, to our knowledge, the first functional characterization of a eukaryotic member of a

11 Here, we describe the identification and functional characterization of a highly specific, regula

12 Here, we report the functional characterization of a multidrug and toxin ext

13 Here we report the functional characterization of a nodule-specific Suc tra

14 tures, ligand-binding properties and in vivo functional characterization of a non-catalytic CHI-fold

15 this study, we report the identification and functional characterization of a novel allosteric MIF in

16 Here, we report the structural and functional characterization of a novel ATPase, Sulfolobu

17 Here, we report the isolation and functional characterization of a novel cis-prenyl diphos

18 Here, we report the functional characterization of a novel mitochondrial pro

19 Here, we report clinical and functional characterization of a novel TNNC1 mutation, A

20 eport the generation and the biochemical and functional characterization of a P221R-mutated IgA2m(1)

21 G12D)-driven lung cancer model, we performed functional characterization of a panel of tumour suppres

22 report describes to our knowledge the first functional characterization of a plant HGO gene, defects

23 In this study, we report the functional characterization of a plant-specific basic he

24 We report here the functional characterization of a Populus class III HD ZI

25 t the 3.3-A resolution crystal structure and functional characterization of a POT family transporter

26 Here, we report the functional characterization of a putative organic Pi tra

27 We report here the sequence and functional characterization of a recombinantly expressed

28 We herein report the functional characterization of a recurrent gain mapping

29 Cloning and functional characterization of a representative set of t

30 Here, we report the identification and functional characterization of a rice epigenetic repress

31 Functional characterization of a subset of GRIN2A mutant

32 Herein we report the bioinformatic and functional characterization of a T6SS-like pathway in di

33 Here, we report the functional characterization of a zinc finger transcripti

34 entification and biochemical, structural and functional characterizations of a novel single-chain (12

35 igh-resolution expression map and a detailed functional characterization of A2AR-CB1R heteromers in t

36 We report expression and functional characterization of AaCAT1, cloned from the f

37 We report the isolation and functional characterization of AaTXKbeta(2)(-)(6)(4), a

38 ularly focusing on the precise molecular and functional characterization of aberrant MDS stem cells i

39 Based upon the functional characterization of adenylation domain specif

40 t genetic system facilitates high-throughput functional characterization of algal genes and accelerat

41 complete thermal, structural, mechanical and functional characterization of all nano-biocomposites wa

42 ultimately leading to the identification and functional characterization of all neuronal subtypes at

43 s in PSTVd isolates and related species, and functional characterization of all possible mutants for

44 ot only accurate discovery, but also for the functional characterization of altered alleles.

45 Here we report the structural and functional characterization of an archaeal CASCADE (aCAS

46 This marks the functional characterization of an endogenous growth fact

47 We report the in vitro and in vivo functional characterization of an ent-kaurene synthase o

48 Functional characterization of an identified novel alter

49 Here we report the identification and functional characterization of an important component of

50 Here we report the development and functional characterization of an in vitro laboratory mo

51 In this article, we report the functional characterization of an mAb that recognizes a

52 We report the isolation and functional characterization of an opium poppy (Papaver s

53 We report the functional characterization of an orphan gene (Triticum

54 nt evidence indicates that the detection and functional characterization of antigen-specific T cell s

55 ghly cross-linked (50% to 70% of total), and functional characterization of apoA1 quantitatively reco

56 ata resource that can aid the biological and functional characterization of ASB ubiquitin ligases.

57 Here, we describe the biochemical and functional characterization of Avena sativa phytochrome

58 Here, we describe the first functional characterization of bas0520, a gene recently

59 Taken together, our functional characterization of BHTC links defense regula

60 f a bacterial homolog (KpBest) of hBest1 and functional characterizations of both channels.

61 A functional characterization of BrnT by site-directed mut

62 omic profiling of cancer cell lines and from functional characterization of cancer cell dependencies,

63 road utility of the Degron-KI system for the functional characterization of cancer genes.

64 T/MR imaging for the detection, staging, and functional characterization of cancer, this new technolo

65 across cancer types, the identification and functional characterization of candidate driver genetic

66 efit from having a standardized platform for functional characterization of candidate variants in the

67 Functional characterization of CD47 in sorafenib-resista

68 We describe the identification and functional characterization of cdgB (SCO4281), a recentl

69 Our findings provide the first functional characterization of cdk10 in vertebrate devel

70 spectroscopy and quantitative phase imaging, functional characterization of cellular structure and dy

71 sfection should facilitate a more widespread functional characterization of clinical HBV isolates, wh

72 Here we report on the functional characterization of components of a potential

73 Functional characterization of CpsA confirmed that the D

74 fort has gone towards the identification and functional characterization of CREs and associated epige

75 Here, we describe the functional characterization of Cs1,6RhaT, a 1,6-rhamnosy

76 Herein, we report the functional characterization of CsBGlu12, a beta-glucosid

77 This in vitro approach to functional characterization of CSCs and their differenti

78 Functional characterization of cse4 phosphorylation muta

79 These results provide the first functional characterization of CTRP13 and establish its

80 However, functional characterization of CYPs has been challenging

81 ssays with WRC tissue extracts, cloning, and functional characterization of cytochrome P450 monooxyge

82 In this context we report here molecular and functional characterization of DhPPZ1 from Debaryomyces

83 iew discusses new findings in phenotypic and functional characterization of different subsets of macr

84 Mean outcome was the morphologic and functional characterization of different subtypes of mac

85 der and schizophrenia.SIGNIFICANCE STATEMENT Functional characterization of disease-associated varian

86 Functional characterization of distinct inhibitory neuro

87 recent curation effort focuses on providing functional characterizations of distinct subfamily archi

88 that has been made in the identification and functional characterization of DNA sequence variants ass

89 Here we report the functional characterization of EFA6R.

90 In this report, we describe the first functional characterization of EhMIF.

91 Functional characterization of ER regulation by Twist wa

92 Here we report our physical and functional characterizations of Est3 homologues from Can

93 However, a detailed functional characterization of excitatory and inhibitory

94 bank of the inferior arcuate sulcus, but no functional characterization of F5a at the single-cell le

95 Here, we report the functional characterization of four CfTPSs using in vitr

96 Functional characterization of four genes (PSEUDO-RESPON

97 Functional characterization of four selected missense mu

98 Here, we report the clinical, genetic, and functional characterization of four TNNC1 rare variants

99 by establishing important groundwork for the functional characterization of FtsB in vivo.

100 However, gene silencing often hampers the functional characterization of gene clusters captured on

101 candidates and enlarging the toolbox for the functional characterization of gene regulation in the hi

102 tworks provide fundamental insights into the functional characterization of genes and their products,

103 on the recent progress made on isolation and functional characterization of genes encoding biosynthet

104 on the recent progress made on isolation and functional characterization of genes encoding biosynthet

105 and show that this grouping could facilitate functional characterization of genes in these families.

106 strains have recently become available, the functional characterization of genes is significantly la

107 iours, and provide a general approach to the functional characterization of genetically identified su

108 neurons have prevented a more comprehensive functional characterization of ghrelin-responsive neuron

109 This functional characterization of GIV's GEF motif provides

110 Together, our studies provide the first functional characterization of Gle1 in vertebrate develo

111 in combination with PET imaging studies for functional characterization of GLUTs in BC.

112 We here report the functional characterization of GmBZL2 (relatively highly

113 Future large-scale studies with functional characterization of GWAS findings are warrant

114 Here, we present a functional characterization of HDC1 in Arabidopsis thali

115 In this study, we report the functional characterization of heterotrimeric G-proteins

116 r both the identification and structural and functional characterization of homologous proteins from

117 he past decade, molecular identification and functional characterization of host factors in the virus

118 n spite of many successes of recent studies, functional characterization of human allelic variants re

119 The structural and functional characterization of human enzymes that are of

120 Independent functional characterization of human Th1, Th2, Th17, T f

121 ides further evidence for the phenotypic and functional characterization of human Vgamma9Vdelta2 T-ce

122 Here we report the crystal structure and functional characterization of human Wapl.

123 scovery efforts are transitioning toward the functional characterization of implicated genetic variat

124 While identification and functional characterization of in vivo phosphorylation s

125 Functional characterization of individual cells within h

126 Functional characterization of LDSP in an Arabidopsis (A

127 llowed, to our knowledge for the first time, functional characterization of LITRs in an autologous sy

128 les lie between transcriptome sequencing and functional characterization of lncRNAs: identifying trul

129 Here we provide an in-depth functional characterization of LytB, the peptidoglycan h

130 ent reverse genetics platforms to facilitate functional characterization of M. truncatula genes.

131 Though its genome has been sequenced, functional characterization of many Ae. aegypti genes, p

132 ith those of related herpesviruses has eased functional characterization of many MDV genes.

133 that led ultimately to the cDNA cloning and functional characterization of many of today's best-know

134 present the first data on identification and functional characterization of Mate proteins in zebrafis

135 and transmitted by membrane-bound proteins, functional characterization of membrane-associated NAC t

136 We extend functional characterization of Merlin-Hippo signaling by

137 The identification and functional characterization of microbial communities rem

138 This study lays a critical framework for functional characterization of miRNAs in healthy and dis

139 Here we describe the first receptor-level functional characterization of mitragynine and related n

140 Notably, functional characterization of model interface domain mu

141 This work completes the structural and functional characterization of mono- and di-domain ARO/C

142 the discovery, biosynthesis, elicitation and functional characterization of monocot terpenoid phytoal

143 Our results provide a functional characterization of mossy cells in the behavi

144 the role of CAFs in NSCLCs, a cross-species functional characterization of mouse and human lung CAFs

145 Phenotypic and functional characterization of MR1T cell clones showed m

146 eported herein should prove of value for the functional characterization of MTs, MT complexes, and MT

147 transferases (MTases) permitted not only the functional characterization of multiple, yet undescribed

148 eport here the expression, purification, and functional characterization of murine IFN (mIFN).

149 the best of our knowledge, this is the first functional characterization of mutant FOS proteins found

150 ze the importance of genetic testing and the functional characterization of mutant receptors for pati

151 Functional characterization of mutant Slo2 channels sugg

152 Functional characterization of mutants with altered TOP

153 Functional characterization of MYB110a showed that it wa

154 MAIThi congenic strain allows phenotypic and functional characterization of naturally occurring mouse

155 Here we report the first functional characterization of new split inteins previou

156 TEC domain will facilitate the discovery and functional characterization of new T6SS effectors in Gra

157 nscript analysis was performed subsequent to functional characterization of NG2 cells.

158 Functional characterization of nine genes representing m

159 the utility of high-throughput screening for functional characterization of noncoding DNA and reveal

160 Functional characterization of noncoding sequences is cr

161 ) that provides a versatile approach for the functional characterization of novel cancer genes and ad

162 We present a detailed functional characterization of one of the genes, bicd-1,

163 Here, we first describe functional characterization of ORF131b (gp17) and ORF436

164 phenotype of HCN1-deficient mice, a detailed functional characterization of pacemaker mechanisms in s

165 Functional characterization of patient fibroblasts showe

166 Functional characterization of patients' fibroblasts and

167 We present here a functional characterization of PcalRG, a novel reverse g

168 Functional characterization of pCRY was performed based

169 which mitochondria can accumulate Ca(2+), a functional characterization of plant MCU homologs has be

170 Complementary biophysical and functional characterization of point mutants and truncat

171 Here, we report the functional characterization of poplar orthologs of MYB46

172 Despite the functional characterization of POT family members in bac

173 These include studies in gene mapping, functional characterization of previously associated gen

174 rmed an extensive anatomical, molecular, and functional characterization of prominent DA transgenic m

175 The functional characterization of proteins requires the des

176 ole in the identification and structural and functional characterization of proteins.

177 Here, we report the first functional characterization of PRX17 (At2g22420), one of

178 Functional characterization of PTP1BDelta6 revealed a po

179 somatic genome engineering approach enables functional characterization of putative cancer genes in

180 This study reports the isolation and functional characterization of rainbow trout (Oncorhynch

181 However, the functional characterization of RD3 in tumor systems has

182 Yet, the topological and functional characterization of real GRNs is often still

183 Functional characterization of recombinant CYP6P9b confi

184 Functional characterization of recombinant wild-type Arg

185 Functional characterizations of recombinant human RyR2-G

186 Functional characterization of REM1.3 revealed that it i

187 The genomics-enabled functional characterization of responses to the challeng

188 Here, we describe the functional characterization of RISAP, a RAC5 effector id

189 Here, we describe the first functional characterization of S.

190 Functional characterization of SCN10A variants was perfo

191 we present the expression, purification, and functional characterization of seven Pgl enzymes.

192 The identification and functional characterization of Si transporters can be ex

193 a-2 agonists and antagonists will facilitate functional characterization of sigma-2 receptor ligands

194 lassification of neuronal cell types and the functional characterization of single neurons, we presen

195 and adults and provide a basis for detailed functional characterizations of single zebrafish Mate tr

196 lvement of MMPs was addressed by cloning and functional characterization of Sl2-MMP and Sl3-MMP from

197 Our preliminary functional characterization of smAKAP provides evidence

198 Here we report the genetic and functional characterization of somatic mutations affecti

199 owerful tools for the unbiased discovery and functional characterization of specific genetic elements

200 However the functional characterization of specific instances remain

201 Spiking statistics and our functional characterization of spikelet activity indicat

202 is finding suggests that further genetic and functional characterization of SPRR3 should be performed

203 omes how can we accelerate the discovery and functional characterization of sRNAs in diverse organism

204 The functional characterization of sRNAs is challenging and

205 Further detailed structural and functional characterization of subtype-switched Epa1 var

206 Together, the subcellular localization and functional characterization of SYT1 highlights a putativ

207 In this report, we describe the cloning and functional characterization of TaLsi1, a wheat Si transp

208 f this study was to provide a phenotypic and functional characterization of TANs in surgically resect

209 Here, we report the biochemical and functional characterization of TbKIN-C, a trypanosome-sp

210 Functional characterization of Tet proteins has been com

211 Functional characterization of Tet TKO ESCs revealed a r

212 Functional characterization of the 40%-identical ortholo

213 ledge, high-resolution taxonomic and protein functional characterization of the ancient oral microbio

214 Here, we report the molecular and functional characterization of the Arabidopsis LSM gene

215 The biochemical and functional characterization of the At2g20340 gene produc

216 describe the solution-based biophysical and functional characterization of the bacteriophage lambda

217 al products in hand, we undertake a detailed functional characterization of the biological activities

218 The production, crystal structure, and functional characterization of the C-terminal cysteine-r

219 irectly from native nanodiscs, which enables functional characterization of the channel by electrophy

220 Functional characterization of the coding sequences in a

221 In addition to detailed functional characterization of the coding variants, AnnT

222 ponents necessary to carry out CME; however, functional characterization of the components is still i

223 Functional characterization of the disease gene revealed

224 Here we report the functional characterization of the DNA glycosylase/lyase

225 Here, we present the functional characterization of the effector See1 (Seedli

226 We describe here the identification and functional characterization of the enzyme O-GlcNAcase (O

227 the present study, we report the cloning and functional characterization of the enzymes responsible f

228 been demonstrated by the identification and functional characterization of the first plant Golgi-res

229 Here we report the identification and functional characterization of the first protozoan panto

230 Here, we report the purification and functional characterization of the full-length Red1 prot

231 Functional characterization of the GCM2 variants and del

232 Here, we report the functional characterization of the GG motif using MoaA,

233 Here, we describe a comparative functional characterization of the Hpa RXLR effector gen

234 spite significant progress in structural and functional characterization of the Hsp70 proteins fundam

235 Functional characterization of the human genome requires

236 Here we report on the functional characterization of the hypothetical protein

237 Here we report biochemical, biophysical, and functional characterization of the interaction between D

238 For a full functional characterization of the L176F mutant we expre

239 The identification and functional characterization of the leucine zipper is an

240 ic analyses and an exhaustive phenotypic and functional characterization of the lymphocyte compartmen

241 control their architecture, we have begun a functional characterization of the maize mutant grassy t

242 n lantibiotics, and serve as a basis for the functional characterization of the many lantibiotic-like

243 This review discusses the functional characterization of the microbiome, highlight

244 udy we performed a genetic, biochemical, and functional characterization of the moss Physcomitrella p

245 Functional characterization of the most highly mutated D

246 Functional characterization of the mouse genes, hence, h

247 Functional characterization of the mTOR signaling pathwa

248 Functional characterization of the mutants demonstrated

249 entation when a only partial topological and functional characterization of the network is available.

250 We performed an extensive functional characterization of the newly established VGA

251 nstrained randomizations do not preserve the functional characterization of the nodes in the referenc

252 We present here a structural and functional characterization of the PerR from the pathoge

253 regulators, taking advantage of the detailed functional characterization of the regulatory region of

254 Functional characterization of the subZI was tested via

255 Toward the functional characterization of the TRIF:ADAM15 interacti

256 Structural and functional characterization of these assemblies requires

257 a3 and mutant alpha3 and alpha6 subunits and functional characterization of these co-expressed with b

258 gar production and glycan formation, but the functional characterization of these enzymes and the ful

259 et host immune responses, identification and functional characterization of these factors can provide

260 This is the first example of functional characterization of these JadX-like proteins,

261 Functional characterization of these mutations showed ab

262 Functional characterization of these target antigens rev

263 In planta functional characterization of these TPS enzymes showed

264 Functional characterization of these two lineages of CD1

265 Functional characterization of these two O-methyltransfe

266 We report here the crystal structure and functional characterization of this atypical NAT.

267 nological advance enabled the structural and functional characterization of this elusive but essentia

268 We performed functional characterization of this gene in relation to

269 process that limits detailed structural and functional characterization of this important class of p

270 man brain and will set the stage for further functional characterization of this novel DNA modificati

271 Here we complete the functional characterization of this protein family by de

272 A detailed functional characterization of this substitution is lack

273 However, functional characterization of those fields has been lar

274 al process, and molecular function, enabling functional characterization of thousands of proteins.

275 e we report the transcriptional profiles and functional characterization of three An. gambiae IR (AgI

276 TATL-seq are useful tools for annotation and functional characterization of TLs, and can be applied t

277 In this paper, we report on the functional characterization of tobacco (Nicotiana tabacu

278 Functional characterization of transcripts specific to d

279 Assay (OSTA), should greatly facilitate both functional characterization of transporters as well as h

280 Numerous examples of the structural and functional characterization of transporters, ion channel

281 Functional characterization of TSHR mutants confirms the

282 Functional characterization of tumor-associated gammadel

283 Functional characterization of two bed bug odorant recep

284 We describe the structural and functional characterization of two functionally coupled

285 Here, we present a structural and functional characterization of two neutralizing antibodi

286 Here, we report the identification and functional characterization of two R2R3-MYB-type transcr

287 We report here the discovery and functional characterization of two S. divinorum diterpen

288 We present the functional characterization of type B Ggamma subunit (Sl

289 Here we report the identification and functional characterization of UAS homologs from avascul

290 we report a design, synthesis, and detailed functional characterization of unique strongly biased al

291 Functional characterization of unknown genes is a challe

292 his communication reports the structural and functional characterization of urotoxin, the first K(+)

293 structural model not only offers an improved functional characterization of V1 neurons, but also prov

294 These results suggest that functional characterization of variants within MODY gene

295 The structure of SubAB and the accompanying functional characterization of various mutants of SubAB

296 We report the identification and functional characterization of VGCC beta-anchoring and -

297 Therefore, the identification and functional characterization of viral genetic determinant

298 Therefore, the identification and functional characterization of viral genetic factors imp

299 Functional characterization of virion-associated host fa

300 /Deltaex13mice, we provide the first in vivo functional characterization of ZC3H14 as a regulator of