ライフサイエンスコーパス: functional genomics

1 method for programmable and high-throughput functional genomics.

2 rtunities, including studies in the field of functional genomics.

3 ues which can utilize as a potential tool in functional genomics.

4 rapid development of liver cancer models and functional genomics.

5 s feasible and has exciting implications for functional genomics.

6 nucleases is transforming genome editing and functional genomics.

7 solution transcriptional analysis coupled to functional genomics.

8 making it a potential model plant for orchid functional genomics.

9 consequently used in function prediction and functional genomics.

10 ting channel catfish genetic enhancement and functional genomics.

11 as evolved into the study of high-throughput functional genomics.

12 reverse- and forward-genetics tool in plant functional genomics.

13 etwork modules specific to colorectal cancer functional genomics.

14 processes in eukaryotes and for comparative functional genomics.

15 ecules are among the most promising tools in functional genomics.

16 utants is a valuable resource for efforts in functional genomics.

17 roughput protein engineering experiments and functional genomics.

18 technology have emerged as a major tool for functional genomics.

19 Gateway cloning system for gene cloning and functional genomics.

20 ing the utility of this collection for plant functional genomics.

21 Insertional mutagenesis is a cornerstone of functional genomics.

22 is a crucial foundation for comparative and functional genomics.

23 RNAi screens are widely used in functional genomics.

24 wheat, thus opening up their pan-genomes to functional genomics.

25 gineering platforms and their application to functional genomics.

26 t CRISPR screens have shown great promise in functional genomics.

27 individuals of European origin from the 200 Functional Genomics (200FG) cohort in the Human Function

28 A series of tools and resources, including functional genomics, a genome sequence, proteomics and m

29 fluenza virus is still obscure, our previous functional genomics analyses revealed a correlation betw

30 Comprehensive bioinformatics and functional genomics analyses were used to identify key r

31 In summary, our functional genomics analysis highlighted novel genes and

32 A functional genomics analysis of expressed heavy and ligh

33 what is, to our knowledge, the first global functional genomics analysis of L. casei symbiosis.

34 We performed a multidimensional functional genomics analysis to integrate genome-wide di

35 amline the process from variant discovery to functional genomics analysis, resulting in an off-the-sh

36 sequence information has hitherto precluded functional genomics analysis.

37 heterogeneity induced by condition change in functional genomics analysis.

38 r control and PAH lung pericytes followed by functional genomics analysis.

39 Here, we used functional genomics and an in vitro human lung epithelia

40 both normal and pathological aspects of the functional genomics and anatomy of the CNS.

41 Current genetic screens, functional genomics and biochemical analyses have identi

42 Here we use whole-genome sequencing, functional genomics and biochemical assays to reveal the

43 Further, with functional genomics and biochemical dissection we demons

44 ant role in the fields of synthetic biology, functional genomics and bioengineering.

45 a has the potential to rapidly advance algal functional genomics and biotechnology.

46 structural variation system for dosage-based functional genomics and breeding of poplar.

47 ocomplex approach has the potential for both functional genomics and cancer therapy.

48 that integrates new patient-derived models, functional genomics and chemical screens to facilitate t

49 Recent progress in functional genomics and chromatin biology illustrates ho

50 tion (SSM) is an important tool for mosquito functional genomics and comparative gene expression stud

51 y available tool to aid our understanding of functional genomics and comparative genomics.

52 to edit the plant genome are much needed for functional genomics and crop improvement.

53 will provide novel means for studying human functional genomics and development.

54 d pluripotency, providing a novel system for functional genomics and developmental research in humans

55 ich will aid in the advancement of tools for functional genomics and elucidation of the biosynthesis

56 reat potential as designer viruses to pursue functional genomics and for the rational design of novel

57 sons and retroviruses are versatile tools in functional genomics and gene therapy.

58 rologous genomic or metagenomic libraries in functional genomics and genome engineering is the low ex

59 Applying functional genomics and genome-engineering, we demonstra

60 rence (RNAi) has become an important tool in functional genomics and has an intriguing therapeutic po

61 A combination of proteomics, functional genomics and in vivo studies presented here i

62 user-provided private and publicly available functional genomics and interaction datasets, 3) queryin

63 able elements, which is an important tool in functional genomics and is well established in several c

64 e on a par with their identification through functional genomics and large-scale cataloguing of tumou

65 ral and/or spatial control are invaluable to functional genomics and medical research.

66 Using a combination of functional genomics and mouse genetics, we identified a

67 l mRNA patterns, which will be essential for functional genomics and network inference in higher orga

68 wSeq may serve as a rapid screening tool for functional genomics and offer the opportunity to explore

69 approaches to uncovering gene function using functional genomics and other approaches.

70 The functional genomics and other experimental resources tha

71 rocess that has multiple applications within functional genomics and personalized medicine.

72 sults demonstrate the potential of combining functional genomics and population genetics approaches f

73 practical resource available for the broader functional genomics and population genetics communities,

74 y providing an invaluable tool to accelerate functional genomics and proteomic research in monocot an

75 Deployment of these vectors can facilitate functional genomics and proteomics and identification of

76 an be used as tools for research, especially functional genomics and proteomics and interfering with

77 ipennis enhance our understanding of cysLGIC functional genomics and provide a useful basis for the s

78 Here, we exploited the functional genomics and reverse genetic approaches to id

79 A report of the Wellcome Trust Functional Genomics and Systems Biology Conference, Hinx

80 ating and advancing our understanding of the functional genomics and systems biology of any process f

81 ill accelerate our understanding of mosquito functional genomics and the development of novel vector

82 A-seq data, provides a valuable resource for functional genomics and tools for breeding elite Hevea c

83 technologies are widely used in the field of functional genomics and used in an increasing number of

84 of the entirely new fields of study called "functional genomics" and "systems biology." These new fi

85 -throughput sequencing, structural genomics, functional genomics, and chemical genomics into unified

86 g biological knowledge from model organisms, functional genomics, and integrative approaches can empo

87 ation sequencing with selection, transplant, functional genomics, and mapping studies.

88 n of phenotypes has become a crucial tool of functional genomics, and several large international pro

89 ries of variable size and coverage depth for functional genomics application.

90 ssage of high-quality data into a variety of functional genomics applications, including de novo asse

91 Here, a functional genomics approach identified the full complem

92 In the present study, an integrative functional genomics approach shows that genetic datasets

93 We also developed a functional genomics approach that assigns putative funct

94 ress this, we implemented a multidimensional functional genomics approach that incorporates 7 differe

95 We take a functional genomics approach to congenital heart disease

96 te and applied an integrated data-mining and functional genomics approach to identify a rheostat of D

97 Herein, we used a biochemical and functional genomics approach to identify the sand fly sa

98 In summary, through a functional genomics approach, pathways essential in the

99 Using a functional genomics approach, we have identified a petun

100 By applying a functional genomics approach, we identified several nove

101 Using a functional genomics approach, we identified two potentia

102 ion through an integrated bioinformatics and functional genomics approach.

103 o has been identified and characterised by a functional genomics approach.

104 d by pathogenic influenza viruses, we used a functional-genomics approach to compare gene expression

105 High-throughput functional genomics approaches have provided insight int

106 Functional genomics approaches offer a means to discover

107 In conclusion, functional genomics approaches reveal the architecture o

108 Here we discuss the use of functional genomics approaches that integrate transcript

109 Functional genomics approaches that leverage the RNAi pa

110 ssue of Cell use genome-wide association and functional genomics approaches to provide deep insights

111 Using in vitro, in vivo and functional genomics approaches, we examined infections b

112 Recently, by applying integrative functional genomics approaches, we identified and interr

113 loid-centric cell biological, proteomic, and functional genomics approaches.

114 as the potential to become a useful tool for functional genomics, as well as for combating protein-ex

115 d the BMP pathway and serve as an example of functional genomics-based hypothesis generation.

116 ucture prediction plays an important role in Functional Genomics by providing structural models of ge

117 on of physiology with population biology and functional genomics can be especially informative.

118 Functional genomics can be used to screen for plant adap

119 We demonstrate that functional genomics can complement traditional sequence

120 Second, we used a comprehensive Convergent Functional Genomics (CFG) approach to identify and prior

121 We have used a translational convergent functional genomics (CFG) approach to identify and prior

122 We then used a Convergent Functional Genomics (CFG) approach to prioritize the can

123 Third, we used a convergent functional genomics (CFG) approach to prioritize these g

124 We then used a convergent functional genomics (CFG) approach with existing prior e

125 Evolutionary conservation, functional genomics, chromatin state, sequence motifs an

126 Existing tools utilize functional genomics data and evolutionary information to

127 The analysis of functional genomics data and genome-scale mutant librari

128 integrated our data with publicly available functional genomics data and identified a growth regulat

129 d provides an efficient intermediary between functional genomics data and reverse-genetics resources

130 provides resources to facilitate modeling of functional genomics data and structural and functional a

131 on in a population of European ancestry, (3) functional genomics data comprised of protein-protein in

132 diction tool that integrates a wide range of functional genomics data for P. falciparum to aid in the

133 Integrated analyses of functional genomics data have enormous potential for ide

134 The ArrayExpress Archive of Functional Genomics Data is an international functional

135 tissue specificity in global integration of functional genomics data is challenging, as "functionali

136 The ArrayExpress Archive of Functional Genomics Data is one of three international f

137 Functional genomics data provides a rich source of infor

138 tuitive 'exploration-style' visualization of functional genomics data relating to the malaria parasit

139 al regulatory network inference from diverse functional genomics data sets and demonstrate their valu

140 We leverage functional genomics data sets for three organisms--H. sa

141 cess several public interaction networks and functional genomics data sets through the portal as well

142 82 individuals by uniformly processing 1,263 functional genomics data sets, developing approaches to

143 , visualize and integrate large-scale tomato functional genomics data sets.

144 and continually expanding large-scale tomato functional genomics data sets.

145 It is compatible with emerging functional genomics data standards and provides data imp

146 e three international public repositories of functional genomics data supporting publications.

147 The integration of genome-wide functional genomics data, followed by the construction o

148 th random graphs and graphs constructed from functional genomics data.

149 eir accurate annotation and integration with functional genomics data.

150 GOModeler, supports hypothesis testing from functional genomics data.

151 organisms that often have a large amount of functional genomics data.

152 lected data from the ArrayExpress Archive of Functional Genomics Data.

153 erstanding of both GWAS and eQTL results and functional genomics data.

154 Tomato Functional Genomics Database (TFGD) provides a comprehen

155 Functional Genomics Data is an international functional genomics database at the European Bioinformat

156 e motifs, evolutionary patterns, and diverse functional genomics datasets from a variety of cell type

157 GeneDB and elsewhere with a wide variety of functional genomics datasets made available by members o

158 Functional genomics efforts face tradeoffs between numbe

159 ular mutations, as well as for the design of functional genomics experiments and for decision support

160 Microarray technology, as well as other functional genomics experiments, allow simultaneous meas

161 of Data is an open web resource for analysed functional genomics experiments.

162 markers also have value beyond B. napus for functional genomics, facilitated by the close genetic re

163 Functional genomics (FG) screens, using RNAi or CRISPR t

164 ct isoform function have been limited in the functional genomics field.

165 The work provides a functional genomics foundation for understanding neural

166 A combination of functional genomics, gene expression, in vivo and in vit

167 1 CRISPRi system will have broad utility for functional genomics, genetic interaction mapping and dru

168 The advent of functional genomics has enabled the genome-wide characte

169 The advent of next-generation sequencing for functional genomics has given rise to quantities of sequ

170 ntional pathology with genomic profiling and functional genomics have begun to enhance our understand

171 nt advances in DNA sequencing technology and functional genomics have stimulated a new wave of invest

172 In the postgenomic era, functional genomics, however, strongly demands such a me

173 oduces stable transgenic lines essential for functional genomics; however, transient expression of ta

174 Adam has autonomously generated functional genomics hypotheses about the yeast Saccharom

175 is a curated online resource for comparative functional genomics in crops and model plant species, cu

176 ramene is an online resource for comparative functional genomics in crops and model plant species.

177 it is expected to revolutionize the field of functional genomics in Dictyostelium by greatly expandin

178 erging model system for both comparative and functional genomics in grass species.

179 -generated RNAi is an effective strategy for functional genomics in rust fungi.

180 and allows an assessment of the progress in functional genomics in the past 12 years.

181 the mouse model was refined with comparative functional genomics in the VMC gene expression profiles

182 high throughput leaf metabolomics along with functional genomics in wild tomato unreveal potential ro

183 eighting each GWAS by using information from functional genomics increased the number of loci with hi

184 increase statistical power is to incorporate functional genomics information, especially gene express

185 dogene annotations with the extensive ENCODE functional genomics information.

186 interference (RNAi) in molecular biology and functional genomics is a well-established technology, in

187 One of the goals of functional genomics is to understand the regulatory impl

188 In functional genomics, it is frequently useful to correlat

189 ning strategy, combined with comparative and functional genomics, led to the identification of the Co

190 ese two species and their comparisons at the functional genomics level to support tailor-designed bre

191 molecular Fluorescence Complementation-based functional genomics method to perform a high throughput

192 In this study, we developed an integrative functional genomics methodology to identify cancer susce

193 We used a functional genomics methodology to interrogate human chr

194 Recent work employing functional genomics now suggests that, indeed, certain f

195 n is a platform-independent resource for the functional genomics of a wide range of microbial systems

196 ch will open doors to the study of bacterial functional genomics of different species in numerous set

197 rovide a resource for use in comparative and functional genomics of diverse oilseeds.

198 am, microRNA-mediated EBV viral oncogenesis, functional genomics of EBV and its biology, and differen

199 ach will find wider application as a tool in functional genomics of filamentous fungi.

200 ghput infectious cell culture model enabling functional genomics of hepatitis delta virus entry and i

201 Many techniques for studying functional genomics of important target sites of anthelm

202 ll as their development and applications for functional genomics of plant coding and non-coding genes

203 nderstanding the ecological and evolutionary functional genomics of plant cuticles.

204 provide a platform for the evolutionary and functional genomics of satDNAs in pericentric heterochro

205 RNAs, thereby providing a powerful tool for functional genomics of small RNA molecules in plants and

206 Comparative and functional genomics of the "dry rot" fungus Serpula lacr

207 ant applications of the viral vector include functional genomics of the grapevine and disease control

208 nally, it will conclude with examples of the functional genomics of the human microbiome and its infl

209 ls that can be used for investigation of the functional genomics of these loci, and progress has been

210 clerosis and CAD will be learned through the functional genomics of these loci, and the hope is that

211 Through the use of functional genomics on the infected brain stems, we dete

212 This new functional genomics platform has broad potential applica

213 A functional genomics platform to identify novel BIA biosy

214 racterized or modellable entries in the main functional genomics PPI databases BioGRID, IntAct and HP

215 As part of the Human Functional Genomics Project (HFGP), we investigate how d

216 ctional Genomics (200FG) cohort in the Human Functional Genomics Project, obtained over three differe

217 Studies from the Human Functional Genomics Project, presented in Cell and other

218 In three studies within the Human Functional Genomics Project, we assessed the effect of e

219 As part of the Human Functional Genomics Project, which aims to understand th

220 cohorts of Western Europeans from the Human Functional Genomics Project.

221 mutLBSgeneDB provides a useful resource for functional genomics, protein structure, drug and disease

222 a fide isogenic settings for high-throughput functional genomics, proteomics, and regulatory DNA anal

223 ression networks have been a useful tool for functional genomics, providing important clues about the

224 Genomics Data is one of three international functional genomics public data repositories, alongside

225 A large part of functional genomics' public catalogs is based on ChIP-se

226 iew summarizes current GWAS efforts in maize functional genomics research and discusses future prospe

227 The recent surge in genome sequence data and functional genomics research has ushered in the discover

228 lish a standardized RT-qPCR protocol for the functional genomics research in a ladybeetle C. maculate

229 s that NF genes may play in evolutionary and functional genomics research.

230 blic resource for future genetic screens and functional genomics research.

231 itate the rapid creation of mouse models and functional genomics research.

232 eir characterization: structural biology and functional genomics researchers.

233 Using functional genomics resources available for N. crassa, w

234 The recent availability of large-scale functional genomics resources provides an opportunity to

235 g unprecedented opportunities to develop the functional genomics resources required to investigate co

236 vard Medical School and associated DRSC/TRiP Functional Genomics Resources website serve as a reagent

237 A functional genomics screen led to the discovery of Epk1,

238 In a functional genomics screen of mouse embryonic stem cells

239 a cell-based reporter assay, we performed a functional genomics screen to identify genes involved in

240 ppression pathway was identified by way of a functional genomics screening in human hepatoma cells.

241 researchers at all stages of high-throughput functional genomics screening, from assay design and rea

242 a bioinformatic procedure using genome-wide functional genomics screens to identify and prioritize c

243 Finally, comparative functional genomics showed a stringent clustering of CK1

244 Here we apply integrative functional genomics strategies to elucidate global HCV-m

245 cs in populations as a part of an integrated functional genomics strategy.

246 r effector technology is a powerful tool for functional genomics studies and biotechnological applica

247 sed to probe combinatorial gene functions in functional genomics studies and have the potential to ad

248 Since functional genomics studies are mainly concerned with re

249 transformation method should help facilitate functional genomics studies in ferns.

250 ybean and identify regions for synteny-based functional genomics studies in legumes.

251 applications of this viral vector system for functional genomics studies in maize and other monocots.

252 eated a variety of clone and mutant sets for functional genomics studies of Escherichia coli K-12.

253 ction of miRNA in P. aphrodite, and will aid functional genomics studies of orchids.

254 n is a novel model system for structural and functional genomics studies of temperate grasses because

255 Recent functional genomics studies on the diatom Thalassiosira

256 Comparative functional genomics studies the evolution of biological

257 es focus on rare event categorical data, and functional genomics studies typically study the presence

258 s over 20,000 microarray- and sequence-based functional genomics studies, and continues to handle the

259 In functional genomics studies, tests on mean heterogeneity

260 y assignment is crucial for evolutionary and functional genomics studies.

261 drug discovery and in protein structural and functional genomics studies.

262 the relevance of human vascular explants for functional genomics studies.

263 resequencing had been performed, followed by functional genomics studies.

264 cRNAs) have been recently discovered through functional genomics studies.

265 , while allowing one to still carry out many functional genomics studies.

266 me engineering has opened up new avenues for functional genomics studies.

267 Our functional genomics study highlights the utility of NSCs

268 mining hypocotyl length during a large-scale functional genomics study in Arabidopsis (Arabidopsis th

269 -wide association is a powerful approach for functional genomics study of specialized metabolism.

270 A functional genomics study revealed that the activity of

271 learning methods have been commonly used in functional genomics, supervised learning cannot be direc

272 Numerous functional genomics techniques (e.g. machine learning) t

273 milar to human GWASs, it is important to use functional genomics techniques to gain a mechanistic und

274 As and the integration of RNA-seq with other functional genomics techniques.

275 cedented advances in genome-wide sequencing, functional genomics technologies for RNA interference sc

276 ent state of knowledge concerning the use of functional genomics technologies to understand mechanism

277 advances in genomic resources and tools for functional genomics that are shifting the paradigm of wh

278 evelopments in transcriptomics (RNA-seq) and functional genomics that we expect to help us develop an

279 In addition to the potential application in functional genomics, this study provides the foundation

280 We used functional genomics to classify a panel of diverse lipos

281 oot phenotyping, whole-plant physiology, and functional genomics to discover novel root traits and th

282 We demonstrated the use of functional genomics to identify SNPs of potential functi

283 We used comparative functional genomics to integrate transcriptome data from

284 In this study, we used functional genomics to investigate noncytolytic mechanis

285 This study represents the first use of functional genomics to investigate the copper tolerance

286 pigenetics research aligns with the field of functional genomics to provide insights into environment

287 l strategies, high-throughput screening, and functional genomics to uncover new differentiation-based

288 We integrate phenotypic assays with functional genomics to understand how tolerance to a sal

289 th Illumina sequencing as a maize (Zea mays) functional genomics tool.

290 essential for establishing metabolomics as a functional genomics tool.

291 tion as well as for fully exploiting them as functional genomics tools and gene-therapy vectors.

292 se infections by using both conventional and functional genomics tools, we studied 34 cynomolgus maca

293 To facilitate fast-growing needs in functional genomics, two reverse genetics approaches hav

294 on gene discovery, fine mapping of loci, and functional genomics using state-of-the-art technologies.

295 enetic mapping, linkage group selection, and functional genomics was used to identify Pfs47 as a P. f

296 To accelerate legume functional genomics, we developed a Lotus japonicus Gene

297 Using functional genomics, we identify new genes involved in f

298 Continued advances in bioimaging and functional genomics will be important for quantitative a

299 the continuing development of new tools for functional genomics will drive a revolution in the under

300 roscopy-based screens are powerful tools for functional genomics, yielding intracellular information