ライフサイエンスコーパス: functional group

1 an 0.01% of the carbon atoms are bonded to a functional group).

2 d with the electron donating strength of the functional group.

3 mbered Lewis base or Lewis acid as a pendant functional group.

4 , species-specific, or occur at the level of functional group.

5 lar transport given an appropriate choice of functional group.

6 carbon center bearing a C(sp(3)) organoboron functional group.

7 eraction with the negatively charged surface functional groups.

8 synergistic interactions of its constituent functional groups.

9 troscopy is used for the mapping of chemical functional groups.

10 the Xi and found 30 genes clustered in seven functional groups.

11 threonine with fixed spatial orientation of functional groups.

12 of thin graphitic edges and reactive oxygen functional groups.

13 s compatible with a range of redox-sensitive functional groups.

14 ding the characterization of labile sulfated functional groups.

15 er trimer 25 with six stereocenters and five functional groups.

16 ecise identification of desired compounds or functional groups.

17 ce of others, and is compatible with several functional groups.

18 ctors is closely linked to existing chemical functional groups.

19 idation of substrates possessing basic amine functional groups.

20 bonding of ionizable compounds with surface functional groups.

21 hich form strong complexes with Hg via thiol-functional groups.

22 show extensive dynamic relations with other functional groups.

23 y relies on controlling the reactions of the functional groups.

24 e, efficient, and tolerate a wide variety of functional groups.

25 als belonging to key structural elements and functional groups.

26 S2 nanosheets are controlled by the attached functional groups.

27 c conditions in the presence of a variety of functional groups.

28 the active centers, and selective masking of functional groups.

29 presence of other oxidizable and Lewis basic functional groups.

30 rotonation or dissociation of surface active functional groups.

31 termediates enable the reduction of multiple functional groups.

32 selectivity that is enabled by coordinating functional groups.

33 ging magnitudes of effects across guilds and functional groups.

34 unds of different chain length but analogous functional groups.

35 e GONR which is compensated by releasing *OH functional groups.

36 The present method tolerates a wide range of functional groups.

37 iscriminating among free and hydrogen-bonded functional groups.

38 ere formed by replacing of oxygen-containing functional groups.

39 rved dependency on the relative positions of functional groups.

40 d that exhibits tolerance to a wide array of functional groups.

41 ing new conditions that tolerate challenging functional groups.

42 These AMPs have been organized into 6 functional groups, 1 of which, cationic AMPs, has receiv

43 ject to further transformations of the diazo functional group; (2) [3+n]-cycloadditions (n = 1-5) by

44 nes that contain two stereocenters and three functional groups (67-84% yields from a common hydantoin

45 sing 16 sublibraries modified with different functional groups, a highly functionalized aptamer for t

46 With a broader spectrum of functional groups accessible, the PPA/P2 O5 -driven Frie

47 substitutions; 6) protection of the charged functional groups according to the prodrug concept to re

48 pounds the trend in viscosity sensitivity to functional group addition is carboxylic acid (COOH) appr

49 ies at a deeper taxonomic resolution than by functional groups and accounting for the differences in

50 with various oxygen- and nitrogen-containing functional groups and afforded the corresponding ketones

51 click that do not contain any cross-reactive functional groups and by optimizing reaction conditions,

52 stal and geometric relationships between the functional groups and C-H bonds of a substrate has been

53 tematic errors were observed locally for key functional groups and carbon types, and correction facto

54 ls such as this allow focusing on particular functional groups and characterizing their ADMET profile

55 catalyst is compatible with a wide range of functional groups and conditions, making it highly compe

56 e charging and discharging cycles of surface functional groups and have a 1.5 V potential range for b

57 ha-carboxylation of amines that bear various functional groups and heterocycles.

58 ll peptides which were clustered into 5 gene functional groups and majority of them were secretory pr

59 polycyclic complex motifs possessing several functional groups and multiple stereogenic centers.

60 ion binding receptors using the dominant N-H functional groups and neutral and cationic C-H hydrogen

61 us interests because of their highly tunable functional groups and porous structure.

62 ectively with substrates containing multiple functional groups and possible sites of reactivity has r

63 he power of catalysis to activate two common functional groups and provide access to divergent stereo

64 is method is compatible with a wide range of functional groups and provides the monodeuterated produc

65 This process tolerates an array of different functional groups and substitution patterns, and is appl

66 .2.2]-oxazabicycles, bearing four orthogonal functional groups and three stereogenic centers, is show

67 This protocol tolerates a great variety of functional groups and thus provides an efficient entry t

68 We estimated the correlation between functional groups and various environmental variables, a

69 The reaction was tolerant of a wide range of functional groups, and a variety of biaryl amide derivat

70 munities and plant diversity, cover of plant functional groups, and cover of native and non-native pl

71 This system is mild, tolerant of many functional groups, and effective for the preparation of

72 f substrate substitution patterns, sensitive functional groups, and heterocycles are tolerated in thi

73 ymers, layers with high densities of organic functional groups, and robust crosslinked networks.

74 correct juxtaposition of protein side chain functional groups, and transition-state stabilization of

75 The surface functional groups appear to be out-competing the carbona

76 A variety of functional groups are tolerated, and both primary and se

77 activated olefins, featuring a wide range of functional groups, are converted into the corresponding

78 a molecule that contains multiple protected functional groups, are not suitable for selective reacti

79 pH-responsive polymers contain ionic functional groups as pendants in their structure.

80 l treatments, suggesting shifts of microbial functional groups as substrate composition was changing.

81 romatography, exceptional tolerance of alpha-functional groups, as well as alkenes and alkynes, and r

82 more than 25 siloxanes with siloxy or alkoxy functional groups at both termini, and can also be appli

83 l over the introduction of various sensitive functional groups at different positions of the thiazole

84 The introduction of novel functional groups at just one of the four bases in modif

85 ve for nucleophiles bearing OR or equivalent functional groups at the alpha-position.

86 a unique pathway to preferentially introduce functional groups at the B(2) vertex using B(9)-bromo-me

87 of basket subsetOP complexes in addition to functional groups at the basket's rim play a role in the

88 secretory proteins were categorized into 27 functional groups based on Gene Ontology terms, includin

89 ommunities in urban parks responded to plant functional groups, but fungi were under tighter control

90 antiparallel chemistries, in which the same functional group can be channeled into one of two revers

91 ll those isocyanides in which a neighbouring functional group can finely tune the reactivity of the i

92 covery of new chemical reactivity of a given functional group can often result in innovative synthesi

93 A wide variety of functional groups can be attached, from Boc-protected am

94 can catalyze reactions, including oxygenated functional groups, carbon vacancies and holes, edge effe

95 Benefited from the reactive functional groups-carboxyl groups of Alb NPs, p19 protei

96 wed all the isocyanides in which the pendant functional group causes either deviation from or reinfor

97 systematically studying the role of organic functional group chemistry with model minerals, we demon

98 es were consumed by chlorine, Cl-substituted functional groups (Cl-DOM) are reacting with HOBr by dir

99 emical manipulations, which ultimately limit functional group compatibility and broad utility.

100 , and reactions often proceed with very high functional group compatibility and without the productio

101 Excellent functional group compatibility is demonstrated for both

102 cterized by its operational simplicity, high functional group compatibility, and regioselectivity whi

103 silylation reactions often suffer from poor functional group compatibility, low atom economy, and in

104 and benzylic C-H bonds with good yields and functional group compatibility.

105 xhibits exceptional substrate generality and functional group compatibility.

106 related fused heterocyclic systems with good functional group compatibility.

107 ld conditions (-10 degrees C), displays good functional-group compatibility, and employs commercially

108 e derivatives can be prepared with excellent functional-group compatibility.

109 Surface functional groups constitute major electroactive compone

110 Functional groups containing X-X bonds are found in all

111 substantially increase DOM's reduced sulfur functional group content.

112 Surface functional groups contribute to the overall electron flu

113 c intramolecular cycloadditions, under tight functional group control, that facilitate selective conv

114 of graphitization and the amount of surface functional groups, COOH.

115 A wide range of functional groups could be tolerated under the reaction

116 ack silica surface modification and quantify functional group coverage using only solution NMR.

117 nalyzed by chemical composition, morphology, functional groups, crystallinity and thermal properties.

118 processing event; mutation of the catalyzing functional group (D303A) reduces activity by >10(4)-fold

119 or primary amino ozonides, addition of polar functional groups decreased in vivo antimalarial efficac

120 is scalable and tolerates a wide spectrum of functional groups delivering fully substituted unsymmetr

121 turated aldehydes containing a wide array of functional groups, demonstrates the practical utility of

122 s containing an alcohol linked to a reactive functional group, deoxygenation occurred substantially m

123 and should enable the future exploration of functional group dependence during the evolution of nucl

124 etic steps to avoid the presence of the NHAc functional group during glycosylation.

125 on is tolerant of a number of common organic functional groups (e.g., aromatic substituents, halides,

126 Out of 22 defined functional groups, eight are fully in accordance with th

127 ibe an approach to quantifying and comparing functional group (FG) tolerance of synthetic reactions.

128 ic substrates that do not have the necessary functional groups for covalently attaching templates.

129 S) that provides proteins with two different functional groups for post-translational labeling at the

130 fication of complex molecules with disparate functional groups (for example, natural products) is a l

131 more than 200 NMOGs were quantified, and the functional group fractions (including acids, carbonyls,

132 reospecific transformation into a variety of functional groups-from amines and halides to arenes and

133 d by establishing ion channels and an oxygen-functional-group gradient in graphene oxide nanoribbon n

134 For secondary amino ozonides, additional functional groups had variable effects on metabolic stab

135 hree pools of compounds that shared the same functional groups (halides, boronic acids, alkenes, and

136 SARs, demonstrating that the methylenedioxy functional group in DHM is essential while the lactone f

137 and Hydra, but have lost the most important functional group in nematocysts, namely toxins.

138 on pathway to be modulated solely by surface functional groups in a chemically gated-all-around confi

139 and tertiary radicals can be used to install functional groups in a convergent manner, which would ot

140 ossibility to introduce and exploit distinct functional groups in an otherwise non-functional highly

141 principle elucidates the transferability of functional groups in chemistry.

142 Cysteine thiols are among the most reactive functional groups in proteins, and their pairing in disu

143 t Fe(II) was complexed primarily by carboxyl functional groups in reduced NOM.

144 potential role of these additional herbivore functional groups in safeguarding natural controls of al

145 Watson-Crick pairs and the role of specific functional groups in stabilizing a Watson-Crick pair.

146 Functional groups in stearic acid (SA), oleic acid (OA),

147 Allenes are useful functional groups in synthesis as a result of their inhe

148 ctions involving open metal sites or pendant functional groups in the pore as the primary binding sit

149 ng on the relative concentration of reactive functional groups in the sample volume and the intensity

150 bing charge transfer complexes are formed as functional groups in these molecules, such as carboxylic

151 at have a spirocyclic core that preorganizes functional groups in three-dimensional space.

152 e linker length between the diene moiety and functional group, in, e.g., PhS-(CH2)xC( horizontal line

153 ic aldehydes and was tolerant of a number of functional groups including ethers, esters, epoxides, ca

154 g process is compatible with a wide array of functional groups, including an alcohol, aldehyde, epoxi

155 pling partners, and can tolerate an array of functional groups, including carbamate NH, halogen, nitr

156 scope and is compatible with a wide range of functional groups, including esters, aryl halides, aryl

157 b(2-)) ligands, and we analyze the effect of functional group incorporation on their structures and p

158 The PHA bears functional groups inserted along its backbone chain work

159 aging the chemoselective reactivity of novel functional groups inserted within fluorophore scaffolds.

160 The sequential functional group interconversion of amide to acid has al

161 d by chemists are often restricted to simple functional-group interconversions.

162 n enables the introduction of nitrogen-based functional groups into such structures that lack nitroge

163 This functional group is also found in mucin, a component of

164 However, the hydroxamate functional group is shown to cause undesirable effects a

165 of o-aminophenols or catechols with aniline functional groups is chemoselective, mild, and rapid; ho

166 anic compounds with atmospherically relevant functional groups is compiled and analyzed to quantify t

167 the conformational dynamicity of the -B(OH)2 functional group, it is expected that these findings wil

168 However, functional-group Lewis basicity typically depresses cata

169 Silylation and desilylation are important functional group manipulations in solution-phase organic

170 ge of a constituent bond, nor through remote functional group migration.

171 l double bonds, number of methyl- and ethyl- functional groups, molecular weight, and number of ring

172 Functional groups more likely to preserve Fe(II) represe

173 was chosen to study because it has only one functional group (-NH2) that undergoes rapid HDX.

174 The functional grouping of the identified proteins correlate

175 the isostructural ZIF-8, ZIF-90, and ZIF-65 functional groups of increasing polarity (-CH3, -CHO, an

176 organization was supported by the fact that functional groups of spines defined by dimensionality re

177 However, according to the FTIR analyses, the functional groups of the oils were not significantly aff

178 en feasible in the absence of an appropriate functional group on which to attach it.

179 explore the effects of anion structures and functional groups on both device performance and physica

180 calcination process is enough to create the functional groups on MWCNT-ZnO nanowire surface that are

181 The azaBODIPYs containing one and two formyl functional groups on the 1,7-aryl groups present at the

182 Changing the functional groups on the anion significantly alters the

183 Reactivities of epoxide and ketone functional groups on the cycloheptane ring were extensiv

184 significant property tuning by altering the functional groups on the imidazolate linkers.

185 permitting 5-12 periodically spaced carboxyl functional groups on the polymer backbone.

186 Various functional groups on the quinazolinone scaffold were tol

187 tution pattern, tether length and Lewis base functional groups on the rate, enantio- and site-selecti

188 ad understanding of the impact of individual functional groups on the success of a transformation und

189 be readily tuned by symmetrically decorating functional groups on the two benzene rings.

190 dent selection of the position and nature of functional groups on these [3]dendralenes.

191 tify the influence of number and location of functional groups on viscosity.

192 arbon matrices and the kinetic preference of functional groups or carbon matrices for electron transf

193 is bound as U((IV)) to C-containing organic functional groups or inorganic carbonate, while uraninit

194 nctionalized with the most electron donating functional group (p-(CH3CH2)2NPh-MoS2) is the most effic

195 s at locations corresponding to positions of functional groups present on the surface of HSA molecule

196 The functional groups preserve the metallic nature of the Mo

197 When mixed, these complementary functional groups rapidly react in aqueous media at neut

198 uoroarenes containing electronically diverse functional groups, regardless of the substitution patter

199 nd general methods for incorporation of such functional group relationships could thus provide a valu

200 versity gradients (0-3) in a five-year plant functional group removal experiment in a steppe ecosyste

201 erences between relative abundance of faunal functional groups, resulting from environmental variabil

202 a broad range of electronically diverse and functional group-rich aryl fluoride products.

203 The functional group-rich products can be further elaborated

204 cribed is a facile, scalable route to access functional-group-rich gem-difluoroalkenes.

205 Species richness (SR) and functional group richness (FGR) are often confounded in

206 lvent effects, and the interactive effect of functional group(s) on chemical shifts combine to hinder

207 ssible non-activated (that is, not next to a functional group) secondary C-H bonds by means of rhodiu

208 electivity demands (e.g., stereoselectivity, functional group selectivity, and site-selectivity) pers

209 om temperature and tolerates a wide range of functional groups, showing reactivity complementary to t

210 eract with the transporter through different functional groups some of which are common for the two t

211 A functional group such as an amide, carboxylic acid, imid

212 ture of aliphatic and aromatic compounds and functional groups such as amides.

213 5 mol % Pd in general and KF as a base), and functional groups such as methyl ester, NH amido, and en

214 Some functional groups such as nitrogen-fixing cyanobacteria

215 er heteroatoms and can act as a surrogate of functional groups such as olefin and amide as well.

216 particular, alkenes with oxidatively labile functional groups, such as alcohols, aldehydes, sulfides

217 be grown with the incorporation of sensitive functional groups, such as alkyl/aryl halides, azides, a

218 ons, a broad substrate scope is achieved and functional groups, such as ester, ketone, nitrile, nitro

219 h, to date, has mainly targeted nucleophilic functional groups, such as the side chains of serine and

220 tion of similar absorption bands of carbonyl functional groups summing up to a broad, nondistinctive

221 d, and cover of native plant species (of all functional groups) tended to decrease, with increasing e

222 ncorporating the amino acid phenylalanine, a functional group that is conspicuously sparing in the se

223 PCM may itself contain redox-active functional groups that are capable of oxidizing or reduc

224 inkages, chain length, as well as additional functional groups that could interact with the nanoparti

225 , giving rise to multiple embedded layers of functional groups that have an interlayer distance of 2.

226 Cas13a enzyme family comprises two distinct functional groups that recognize orthogonal sets of crRN

227 lved in this reaction tolerate a plethora of functional groups, the process can be applied to the eff

228 kyl iodides; and tolerant of a wide range of functional groups, this method allows rapid access to di

229 chemistry permits efficient installation of functional groups through ortho ester linkages on an ali

230 Equipped with functional groups to accommodate modern drug delivery te

231 erful reagents for the selective transfer of functional groups to nucleophiles, are the properties of

232 al energetic contributions of various ligand-functional groups to the affinity of the entire ligand.

233 ing its environment by introducing different functional groups to the surrounding linkers.

234 ation is driven by the coordination of guest functional groups to the zinc porphyrins.

235 t formal 1,5-alkyl migrations from the ester functional groups to unsaturated carbon-carbon framework

236 activated by using a 'directing' (usually a functional) group to obtain the desired product selectiv

237 ify its properties and incorporate different functional groups, to electrochemical reactions and sele

238 compounds were effective and exhibited broad functional group tolerance across a wide range of fluoro

239 The methodology shows good functional group tolerance and allows synthesis of thiop

240 phine-free one-pot synthesis features a high functional group tolerance and gives access to richly de

241 one-pot transformation allows unprecedented functional group tolerance and it is well-suited for the

242 ned by any method and reveal a high level of functional group tolerance for metal-catalyzed, site-sel

243 Combined with the excellent functional group tolerance of neutral Ni(II) complexes,

244 The method conveys broad functional group tolerance on both components, does not

245 A wide functional group tolerance was observed in the tandem re

246 action is highly versatile and exhibits good functional group tolerance with a range of primary and s

247 rovides milder reaction conditions with high functional group tolerance, and gives the products in mo

248 The reaction shows high efficiency, good functional group tolerance, and high site-selectivity in

249 nd completely atom-economical, exhibit broad functional group tolerance, and occur readily at room te

250 reaction exhibited excellent efficiency and functional group tolerance, producing polysulfonates wit

251 at mild conditions with broad scope and wide functional group tolerance.

252 on of chiral C-N cross-coupled products with functional group tolerance.

253 thereby demonstrating its broad utility and functional group tolerance.

254 llenging substrate combinations and exhibits functional group tolerance.

255 ducts of the ketones are obtained with broad functional group tolerance.

256 tives in good to moderate yields with a wide functional group tolerance.

257 weight, narrow polydispersity and excellent functional group tolerance.

258 tion is high yielding and shows an excellent functional group tolerance.

259 on gram scale with broad substrate scope and functional group tolerance.

260 actions of free amines exhibiting remarkable functional group tolerance.

261 eeds under mild conditions and exhibits good functional group tolerance.

262 (89-98 % de/ee), moderate yields and a wide functional group tolerance.

263 lic compounds with excellent selectivity and functional group tolerance.

264 mportant heterocyclic scaffolds with diverse functional group tolerance.

265 regioselective and proceeds with exceptional functional group tolerance.

266 s C with excellent 1,1-selectivity and broad functional group tolerance.

267 zoxazines with high efficiency and excellent functional group tolerance.

268 This reaction enjoys broad scope and functional group tolerance.

269 ent yields and stereoselectivities with high functional group tolerance.

270 mides with mild reaction conditions and good functional-group tolerance has been developed.

271 operational simplicity, sustainability, high functional-group tolerance, and amenability to gram-scal

272 Of note is the scalability, functional-group tolerance, rapid rate, and the ability

273 features broad substrate scope and excellent functional-group tolerance.

274 , high positional selectivity, and excellent functional-group tolerance.

275 reaction features high selectivity and good functional-group tolerance.

276 ) ) cross-coupling processes, with excellent functional-group tolerance.

277 g ZnCl2 forms organozinc compounds which are functional group tolerant and stable to reactive acyl ch

278 ely functionalized oxazoles is realized in a functional-group tolerant manner using alkynyl thioether

279 We herein report functional group-tolerant and robust C-S couplings of br

280 group in DHM is essential while the lactone functional group tolerates modifications.

281 of protonated model compounds with different functional groups toward trimethoxymethylsilane (TMMS) w

282 ction proceeds through a PCET promoted nitro functional group transfer pathway.

283 sequent introduction of the methyl group and functional group transformation complete the synthesis o

284 ons catalyzed by ArMs, this was done using a functional-group transformation classification.

285 ied to the reduction of a diverse variety of functional groups under mild conditions.

286 as homolytic bond fragmentation of the edge functional groups upon heating up to 600 degrees C under

287 In this report, we show that the enone functional group, upon photoexcitation, provides a solut

288 , the first polymer to contain the ladderane functional group, was synthesized from a gemini monomer

289 s,anti,cis-[3]-ladderane as a characteristic functional group were constructed stereospecifically in

290 ed to the corresponding thioesters, and many functional groups were compatible with this reaction.

291 f the precipitation in the presence of polar functional groups were examined to show the utility and

292 e constants of O((3)P) with thiols and other functional groups were found.

293 pi electrocyclization, in which a variety of functional groups were tolerated.

294 e active site comprising coordination of its functional group, which significantly enhances comonomer

295 ds chemoselectively in the presence of other functional groups, which are typically reduced using con

296 reduce the number of rotatable bonds between functional groups while increasing the stereochemical di

297 the presence of fructose, despite having no functional group with which to bind the saccharide.

298 r tertiary amino ozonides, addition of polar functional groups with H-bond donors increased metabolic

299 Natural products that contain functional groups with heteroatom-heteroatom linkages (X

300 d in the construction of X-X bond containing functional groups within natural products.