ライフサイエンスコーパス: functionally distinct

1 LdtMt5, and found it to be structurally and functionally distinct.

2 w that Arabidopsis KAI2 and D14 proteins are functionally distinct.

3 molecularly defined 5HT neuron subtypes are functionally distinct.

4 es generate AAMs that are phenotypically and functionally distinct.

5 ifferent T cells bearing the same TCR can be functionally distinct.

6 The three Akt isoforms are functionally distinct.

7 heir respective synaptic inputs, making them functionally distinct.

8 al expression recognition in each region are functionally distinct.

9 innate CD8(+) T cells are phenotypically and functionally distinct.

10 istal axis of CA1 of the hippocampus will be functionally distinct.

11 rsus those fusing in response to stimuli are functionally distinct.

12 multitile circuit was also reprogrammed to a functionally distinct 2-bit full adder with 32-set match

13 Cells assemble and maintain functionally distinct actin cytoskeleton networks with v

14 stereotypic proportions from converging but functionally distinct afferents.

15 clin D1 (Ccnd1) mRNA was associated with two functionally distinct AGO-miR complexes.

16 These data support a model whereby these two functionally distinct allosteric networks cooperate to t

17 of gamma-tubulin that are biochemically and functionally distinct and differentially regulated.

18 ports associative memory by interacting with functionally distinct and distributed brain regions has

19 cell type-specific expression patterns were functionally distinct and highly enriched in genes assoc

20 e subunits, BRG/SMARCA4 and BRM/SMARCA2, are functionally distinct and may contribute to complex spec

21 ion and substrate affinity, MtAMT2;1 appears functionally distinct and more important at higher nitro

22 cyte-derived macrophages are now known to be functionally distinct and of separate origin.

23 e tasks rely on information exchange between functionally distinct and often relatively distant neuro

24 Therefore, ERK1 and ERK2 display both functionally distinct and redundant roles in sensory neu

25 Thus, ERK1 and ERK2 exhibit both functionally distinct and redundant roles in sensory neu

26 trasynaptic transmission are molecularly and functionally distinct, and glial cells are known to expr

27 e suggested that the two pale stripes may be functionally distinct, and in marmosets they also differ

28 ses of the CcpA family, but the proteins are functionally distinct, and the extracellular RoxA has ev

29 variate analyses revealed the recruitment of functionally distinct AnG subregions during the retrieva

30 n entorhinal cortex (ERC) is subdivided into functionally distinct anterolateral (alERC) and posterom

31 neurons (Glut4 neurons) in anatomically and functionally distinct areas of the CNS.

32 somatosensory cortex (S1), two adjacent but functionally distinct areas, display striking difference

33 ocortex is parcellated into anatomically and functionally distinct areas.

34 Taxonomically, metabolically and functionally distinct bacterial communities developed be

35 bly of carboxysomes, or any of the myriad of functionally distinct BMCs, into heterologous systems.

36 neurons that operate within anatomically and functionally distinct brain regions.

37 These data demonstrate functionally distinct, but cooperative, roles for each k

38 proteins; (iii) grouping the Dbl family into functionally distinct categories based on both their cat

39 ral killer (NK) cells have been divided into functionally distinct CD3(-) CD56(bright) CD16(-) and CD

40 for Ly6C as a surface marker to distinguish functionally distinct CD4(+) T cells during persistent v

41 nstrate that ES and LS neurons represent two functionally distinct cell classes in the CeL and intera

42 LC projection mapping revealed functionally distinct cell modules with specific anatomi

43 nism relies on cell interactions between two functionally distinct cell populations, and we present e

44 at miRNA profiles differ dramatically across functionally distinct cell types of the mouse jejunal in

45 both robustly and variably expressed across functionally distinct cell types of the murine jejunal e

46 ur experiments provide new insights into the functionally distinct cell types present at the maternal

47 o computing spatial information, composed of functionally distinct cell types such as place and grid

48 work has not accounted for the diversity of functionally distinct cell types that make up the immune

49 Due to functionally distinct cell-mediated immunity, newborns a

50 t planarian neoblasts comprise two major and functionally distinct cellular compartments.

51 ion of SPT activity differentially regulates functionally distinct ceramide synthase activities as pa

52 ry cell walls, a requirement for two or more functionally distinct CESA isoforms for secondary cell w

53 demonstrate that H3K9me2 and H3K9me3 define functionally distinct chromatin states and uncover a mec

54 igenome analyses highlight the importance of functionally distinct chromatin states for accurate cell

55 ntify multiple classes of epigenetically and functionally distinct cis-regulatory elements (CREs).

56 and RMS microglia thus appear to comprise a functionally distinct class that is selectively adapted

57 ealed many neoblast characteristics, whether functionally distinct classes exist within this populati

58 recovery kinetics to synaptic volume in two functionally distinct classes of cells: primary and seco

59 dependent gene regulation and identify three functionally distinct classes of genes that accumulate a

60 tional activation and repression to regulate functionally distinct classes of genes.

61 that myosin 15 isoforms can navigate between functionally distinct classes of stereocilia, and are in

62 Functionally distinct classes of target genes differ in

63 verse HCV strains, assigning the NAbs to two functionally distinct clusters.

64 In metazoans this enzyme is found in two functionally distinct coactivator complexes, SAGA (Spt A

65 speech perception, as in other domains, two functionally distinct coding schemes have been proposed

66 Here, we show two populations of functionally distinct cohesin on chromosomal arms using

67 Another kind of verticality, which might be functionally distinct, comes from navigating on sloped t

68 hically organized within morphologically and functionally distinct compartments.

69 mTOR kinase acts in two functionally distinct complexes, mTOR complex 1 (mTORC1)

70 TOR functions in two structurally and functionally distinct complexes, TOR Complex 1 (TORC1) a

71 hat drives the dynamic assembly of these two functionally distinct complexes.

72 tein operates as part of two molecularly and functionally distinct complexes.

73 ds to different sets of proteins that define functionally distinct complexes: I, I', and II.

74 sts of two otocyst-derived, structurally and functionally distinct components: the dorsal vestibular

75 ied the adrenal cortex, which is composed of functionally distinct concentric layers that develop pos

76 not able to predict the presence of the two functionally distinct conformations just from the knowle

77 ed whether Abeta can assume structurally and functionally distinct conformations within the brain.

78 The mechanistically parallel but functionally distinct conjugation pathways typically req

79 ther these spatial relationships vary across functionally distinct cortical areas are not known.

80 fying spatial receptive fields (SRFs) in two functionally distinct cortical regions in the pallid bat

81 anizational features that generalized across functionally distinct cortical regions.

82 ed connectivity and synaptic signaling among functionally distinct corticospinal populations in Fisch

83 testinal tumors can contain dynamic pools of functionally distinct CSC populations, which seem to int

84 Characterization of functionally distinct dendritic cell (DC) subsets in mic

85 demonstrated that individual Wnt ligands are functionally distinct, despite their partially overlappi

86 as a switch that regulates the expression of functionally distinct DmNmnat variants.

87 controlling gene expression via a family of functionally distinct DNA-binding auxin response factors

88 cording to this model, GPIHBP1 comprises two functionally distinct domains: (1) an intrinsically diso

89 ned that ORF57 contains two structurally and functionally distinct domains: a disordered nonstructura

90 cceptor interactions with three structurally/functionally-distinct donor classes including organic dy

91 ptic inputs, and project to anatomically and functionally distinct downstream targets, including the

92 The C1q assay does not appear to distinguish functionally distinct DSA with clinical significance.

93 nhibition at high concentrations require two functionally distinct E2 approximately ubiquitin substra

94 rated that the E6AP/UBE3A ligase harbors two functionally distinct E2 approximately ubiquitin-binding

95 o velocity, requiring ordered binding at two functionally distinct E2 approximately ubiquitin-binding

96 SNPs have revealed two functionally distinct ecotypes overlapping in the Centra

97 Naive T helper cells differentiate into functionally distinct effector subsets that drive specia

98 suggesting that RELMalpha and RELMbeta have functionally distinct effects on immunity and inflammati

99 enable the derivation of cardiomyocytes and functionally distinct endothelial cell (EC) subtypes fro

100 Notably, we detected a novel class of functionally distinct enhancers enriched in H2BK20ac but

101 d connectivity of spatially intermingled but functionally distinct ensembles.

102 When we do so, does our brain split into functionally distinct entities?

103 ual intracellular uptake of structurally and functionally distinct enzymes providing a convenient, re

104 s indicate that Hsp70 and Hsp90 comprise two functionally distinct ER quality control checkpoints tha

105 Separation of the functionally distinct ESCRT-0 and SNX-1/RME-8 microdomai

106 ganized into hierarchical classifications of functionally distinct families and sub-families.

107 tinguishes these two closely related, though functionally distinct, families.

108 Up to 53% of each mapped, functionally distinct forest presents an opportunity for

109 The two functionally distinct forms of gH/gL present in HCMV mak

110 Melanoma cells can adopt two functionally distinct forms, amoeboid and mesenchymal, w

111 ctors Nfil3 and T-bet but phenotypically and functionally distinct from adipose mature natural killer

112 oth muscle actin and are morphologically and functionally distinct from adjacent precapillary smooth

113 evidence suggests that neonatal immunity is functionally distinct from adults.

114 trate that the chaperone activity of Get3 is functionally distinct from and likely mutually exclusive

115 cells in humans that are phenotypically and functionally distinct from B10 cells and occur in early

116 related BAI protein family member, BAI1, is functionally distinct from BAI3, because it cannot rescu

117 Like Bqt4, MtgA has meiotic roles but is functionally distinct from Bqt4 as MtgA is not required

118 The ipRGCs are structurally and functionally distinct from classical rod/cone photorecep

119 ses of GM-CSF dendritic cells (DCs) that are functionally distinct from conventional DCs (cDCs) and d

120 the least-differentiated memory subset, were functionally distinct from conventional memory cells, an

121 D3+ T cell subset that is phenotypically and functionally distinct from conventional NK and T cells.

122 rocompartment and demonstrate that CsoS2B is functionally distinct from CsoS2A in the assembly of alp

123 bdomains, which are structurally similar but functionally distinct from each other.

124 hat plasma membrane PI(4)P, which we show is functionally distinct from Golgi PI(4)P, forms a steep g

125 collected from Crohn's disease patients are functionally distinct from gut microbiota collected from

126 factor required to counteract MSI, which is functionally distinct from its role in the FA pathway.

127 15, Hxt16 and Hxt17 are phylogenetically and functionally distinct from known polyol transporters.

128 crophages (TAMs) that are phenotypically and functionally distinct from mammary tissue macrophages (M

129 T cells (recent thymic emigrants [RTEs]) are functionally distinct from naive T cells that have compl

130 embryonic piwi-1+ cells are molecularly and functionally distinct from neoblasts: they express uniqu

131 These data collectively suggest that SLN is functionally distinct from PLB; its ability to interact

132 g S-phase itself, respectively, and hence is functionally distinct from previously identified MGS-ass

133 t are transcriptionally, phenotypically, and functionally distinct from recirculating central and eff

134 g hypothesis that unremodeled cardiolipin is functionally distinct from remodeled cardiolipin, at lea

135 LRCs are molecularly and functionally distinct from reporter-marked reserve ISCs.

136 e data indicate that human ex-Th17 cells are functionally distinct from Th1 and Th17 cells, and sugge

137 ialized vasculature that is structurally and functionally distinct from that of the periphery.

138 MP3 indirectly targets MICB with a mechanism functionally distinct from that of ULBP2.

139 ibution in Arabidopsis, should be considered functionally distinct from the canonical plant eIF4E inv

140 d that the telomere deprotection response is functionally distinct from the genomic DNA damage respon

141 CRAMP), encoded by the mouse gene (Camp), is functionally distinct from the human mature peptide (LL-

142 of GIRK1-containing channels, spatially and functionally distinct from the site of channel activatio

143 e AIS-positive cells are morphologically and functionally distinct from their AIS-negative counterpar

144 sue-resident memory (Trm) CD8(+) T cells are functionally distinct from their circulating counterpart

145 RTEs are functionally distinct from their more mature but still n

146 formation of ER-PM contacts sites, which are functionally distinct from those mediated by STIM1 and O

147 data show that phagosomal tubules in DCs are functionally distinct from those that emerge from lysoso

148 These electrodes were intermixed with, yet functionally distinct from, sites that encoded different

149 However, 7TMRs can also activate functionally distinct G protein-independent signaling vi

150 aterians, the Shaker family consists of four functionally distinct gene families (Shaker, Shab, Shal,

151 Finally, we show that functionally distinct glioblastoma stem cells can be sep

152 olgi apparatus by the consecutive actions of functionally distinct glycosidases and glycosyltransfera

153 rks but also divides these states into three functionally distinct groups, of which only one specific

154 nd plasticity measures form structurally and functionally distinct groups.

155 We show that H3K9me2 defines a functionally distinct heterochromatin state that is suff

156 , leading to the production of at least four functionally distinct heterodimers from only five subuni

157 ceptors to mimic the ligand specificities of functionally distinct homologs.

158 We propose the existence of two functionally distinct IMD networks, one in insects and a

159 Their roles appear functionally distinct in that condensin I is required to

160 MtRNAPs are, however, functionally distinct in that they depend on one or more

161 o colony morphologies were taxonomically and functionally distinct in the North Atlantic and North Pa

162 The larger size of the functionally distinct inferior parietal default mode net

163 se diverse pathways innervate excitatory and functionally distinct inhibitory neurons, providing the

164 25 simultaneously elicits phenotypically and functionally distinct innate lymphoid- and nonlymphoid-a

165 ortical microcircuits the integration of two functionally distinct inputs occurs nonlinearly through

166 asses of HSP proteins, previously considered functionally distinct, into a unifying pathway for axona

167 gression, alternative mRNA splicing produces functionally distinct isoforms of Mena, an actin regulat

168 s and nonpacemakers indicate the presence of functionally distinct K(ir) currents in these two popula

169 at least three types of compositionally and functionally distinct L1 RNPs.

170 ates, Endothelin signaling involves multiple functionally distinct ligands (Edns) and receptors (Ednr

171 GluMIs and type 2 OFF bipolar cells possess functionally distinct light-driven responses and may the

172 Our data suggest that functionally distinct LT-CF variants with increased fitn

173 er et al. now describe the generation of two functionally distinct mammalian proteins, MAVS and miniM

174 that rearranging such combinations generates functionally distinct meaning is lacking.

175 lly modified forms of Rb, the temporally and functionally distinct means by which HCMV proteins inter

176 that hair cells express two molecularly and functionally distinct mechanotransduction channels with

177 ory processing and suggest that there may be functionally distinct metacognitive systems in the human

178 The temporally separated and functionally distinct modifications are manifested by ad

179 criptional network can be divided into three functionally distinct modules: Polycomb, Core, and Myc.

180 s and Golgi cells can receive segregated and functionally distinct mossy fiber inputs, enabling Golgi

181 We also identify a related but functionally distinct motif in XLF, WRN, MRI and PAXX, w

182 s release different modulators, which induce functionally distinct motor programs.

183 ytic subunit in two structurally related but functionally distinct multi-component kinase complexes,

184 mologue Neuroglian mediates adhesion between functionally distinct mushroom body axon populations to

185 used in combination to discriminate between functionally distinct myeloid cells and discuss the role

186 terization of a phylogenetically related yet functionally distinct N-methyltransferase (NMT) from opi

187 tory receptors integrate into segregated and functionally distinct neural pathways.

188 in the hindbrain and the spinal cord produce functionally distinct neuron cell types.

189 ABGCs provide two temporally overlapping but functionally distinct neuronal cell populations, adding

190 Synapses are functionally distinct neuronal compartments that are cri

191 We characterize these functionally distinct neuronal populations by comparing

192 We also newly identify a functionally distinct neuronal subpopulation in the STP

193 In order to be functionally distinct, neurons must participate in disti

194 of this study was to investigate the role of functionally distinct NK cell subsets in alloimmunity wi

195 irment, we characterized the distribution of functionally distinct NK cell subsets in the bone marrow

196 Collectively, our results describe a functionally distinct, noncanonical STAT3 phosphoform th

197 ificity of NPY release is conferred by three functionally distinct NPY+ cell types, with differences

198 r a range of temporal frequencies, and three functionally distinct Off bipolar cell types receive con

199 We studied MscL chimeras derived from functionally distinct orthologues: Escherichia coli and

200 These data demonstrate the presence of functionally distinct oxyphil and chief cells within par

201 rimary visual cortex (V1) are organized into functionally distinct parallel processing streams.

202 nd structural modeling of ABHD5 and ABHD4, a functionally distinct paralog that diverged from ABHD5

203 These two anatomically and functionally distinct pathways are likely relevant for c

204 ea, characterizing how their inputs from the functionally distinct pathways change throughout song de

205 ynaptic excitation from L2/3 to L5B into two functionally distinct pathways with different input-outp

206 -specific interventions in the GPe to target functionally distinct pathways, with the potential to in

207 hus, the consolidation of LTM depends on two functionally distinct phases of protein synthesis: an ea

208 ng of melanopsin could provide the basis for functionally distinct photopigments arising from a singl

209 binding proteins as a mechanism to establish functionally distinct pools of a single transcript speci

210 synaptic vesicles which are segregated into functionally distinct pools.

211 synaptic vesicles which are segregated into functionally distinct pools.

212 find that dynein can be in biochemically and functionally distinct pools: either tracking dynamic mic

213 ogether, our data suggest that CD5 defines a functionally distinct population of B cells in humans in

214 ly be more informative to focus attention on functionally distinct portions of genes.

215 Because alpha6-receptors are targeted to functionally distinct postsynaptic sites from alpha1-rec

216 primary human fetal and adult monocytes are functionally distinct, potentially explaining how these

217 , using 98-channel microelectrode arrays, in functionally distinct primary somatosensory areas 3b and

218 entrainment in delta and theta bands reflect functionally distinct processes.

219 ve of the current study was to determine how functionally distinct proinflammatory and anti-inflammat

220 mitotic subunits endow septin complexes with functionally distinct properties.

221 ves organisms the option to express diverse, functionally distinct, protein isoforms.

222 s alternative splicing events to produce two functionally distinct proteins, Mcl-1(S) (pro-apoptotic)

223 t subnuclei of this region are populated two functionally distinct PV-IN networks.

224 Here we show that two functionally distinct regions of the pallid bat auditory

225 Similarly, these subregions overlap with functionally distinct regions showing opposed signal cha

226 Thus, two structurally and functionally distinct regions underlie the majority of s

227 The entorhinal cortex is divided into functionally distinct regions, the medial entorhinal cor

228 The LHb contains two anatomically and functionally distinct regions: lateral (LHbl) and medial

229 and STAT5B, and the extent to which they are functionally distinct, remain uncertain.

230 These anatomically and functionally distinct responses may contribute to the ho

231 For most species, structurally and functionally distinct RGC types appear to have similar t

232 Our results reveal functionally distinct roles of different regions of Tim1

233 e-selective activity suggests that, although functionally distinct, scene and object processing pathw

234 Object size is represented by functionally distinct sectors along the ventral visual p

235 ory (S2) cortices, although anatomically and functionally distinct, share an intriguing cellular comp

236 s with differential degree of OS may provide functionally distinct signals to different downstream ta

237 7 +/- 0.2), requiring ordered binding to two functionally distinct sites per subunit.

238 dress this question, we dissected Munc18c, a functionally distinct SM protein involved in nonsynaptic

239 nic developmental pathways and generation of functionally distinct SMC subtypes.

240 In this study, we generated two functionally distinct sorafenib-resistant human Huh-7 HC

241 lls progressed through transcriptionally and functionally distinct stages and provided differential s

242 mation, and, because they can assume several functionally distinct states of activation, they can eit

243 to be interconvertible and oscillate between functionally distinct states.

244 MYO5A and MYO5B control functionally distinct steps in the surface trafficking o

245 dopamine function in adolescent rats in two functionally distinct striatal subregions: nucleus accum

246 ee major PV cell classes further splits into functionally distinct sub-classes during fast network ev

247 Our analysis revealed two functionally distinct subclasses of release sites differ

248 dendrites likewise contain structurally and functionally distinct subcompartments.

249 lum (ER) membranes (MAM), a structurally and functionally distinct subdomain of the ER.

250 terestingly, the TACC domain consists of two functionally distinct subdomains, CC1 (amino acids (aa)

251 e hippocampus itself contains several small, functionally distinct subfields, examining the role of t

252 ied pathways and complexes but also resolved functionally distinct submodules within larger protein c

253 nd population/cluster analysis to discover a functionally distinct subpopulation of cells.

254 al CR-expressing cells comprise at least two functionally distinct subpopulations based on their resp

255 sical sorting experiments, which assume that functionally distinct subpopulations can be prospectivel

256 er SNc dopaminergic neurons in mice comprise functionally distinct subpopulations distinguished by th

257 Identification of functionally distinct subpopulations in this disease is

258 or any moment in time, selectively activates functionally distinct subpopulations of primary visual c

259 eoplasms in mice contain morphologically and functionally distinct subpopulations that have cancer st

260 e polymodal nociceptive afferents form three functionally distinct subpopulations with beta-alanine r

261 itors and subdivide them into a hierarchy of functionally distinct subpopulations with stepwise chang

262 ated, providing support for the existence of functionally distinct subregions along the parahippocamp

263 iate fMRI analyses, we provide evidence that functionally distinct subregions of angular gyrus (AnG)

264 Furthermore, in a functionally distinct subset of cells that are particula

265 Adherent-invasive Escherichia coli (AIEC), a functionally distinct subset of resident intestinal E. c

266 igorously defined HSCs can be separated into functionally distinct subsets based on c-Kit activity.

267 ls can be classified into phenotypically and functionally distinct subsets based on levels of CD56 re

268 gh differentiation of naive CD4 T cells into functionally distinct subsets of effector T cells (T hel

269 hat UDP-glucose triggers the mobilization of functionally distinct subsets of HSPCs.

270 ctions transiently increase the frequency of functionally distinct subsets of IAV-specific CTLs, in p

271 onse evolves during MeV clearance to produce functionally distinct subsets of MeV-specific CD4(+) and

272 These posttranslational modifications create functionally distinct subsets of microtubule networks in

273 erent modes of MTOR-sensitive translation of functionally distinct subsets of mRNAs, which may explai

274 rives dynamic dendritic and spine changes in functionally distinct subsets of neurons, resulting in f

275 at tissue DCs consist of developmentally and functionally distinct subsets that differentially regula

276 ls represent a heterogeneous population with functionally distinct subsets, and the balance among sub

277 Tfh cells are composed of phenotypically and functionally distinct subsets.

278 nd PTMs that divide the MT cytoskeleton into functionally distinct subsets.

279 s also classify and provide markers for new, functionally distinct subtypes.

280 such cells could be further stratified into functionally distinct subtypes.

281 f the subthreshold RF into a parallel set of functionally distinct subunits.

282 e we present X-ray crystal structures of two functionally distinct SusCD complexes purified from Bact

283 e recycling and coordinated recruitment from functionally distinct synaptic vesicle (SV) pools.

284 The metabolic programs of functionally distinct T cell subsets are tailored to the

285 Further, functionally distinct T cell subsets require distinct en

286 to the recruitment of brain areas across two functionally distinct tasks (visual and semantic).

287 ent of PPC in humans suggest the addition of functionally distinct territories.

288 The structurally homologous, but functionally distinct, Tim1 and Tim3 are significantly l

289 are known, but the requirement for multiple, functionally distinct transcription factors needs clarif

290 dies provide additional markers to delineate functionally distinct Treg subsets that may help direct

291 e are widespread and comprise at least three functionally distinct types.

292 processes via attachment of structurally and functionally distinct ubiquitin (Ub) chains.

293 behavioral modulation in rats is mediated by functionally distinct units of neurons (neural ensembles

294 nd transgenic experiments show that they are functionally distinct, varying in FLC expression level a

295 erent arrangements (AB or BAB) to create two functionally distinct vocalizations.

296 neurophysiological correlates and are likely functionally distinct, which has important implications

297 They do so by using two functionally distinct whisker systems: the macrovibrissa

298 osed IL-17+ CD4+ T cells are molecularly and functionally distinct, with a unique gene signature char

299 that nuclei subdivide a common cytosol into functionally distinct yet mobile compartments.

300 mal-matrix axis, and furthermore, indicate a functionally distinct zone at the striosome-matrix inter