ライフサイエンスコーパス: fundamental mechanism

1 a clinically oriented understanding of these fundamental mechanisms.

2 However, the fundamental mechanism about the catalytic activity of 1T

3 Consistent with effects on these fundamental mechanisms, allelic variants of ALOX12 are a

4 re of such enhanced plasticity may provide a fundamental mechanism allowing adult-born neurons within

5 duals with schizophrenia are associated with fundamental mechanisms and symptoms of the disorder, as

6 The fundamental mechanism appears to be common to all of the

7 This fundamental mechanism appears to be universal across cel

8 The fundamental mechanisms are debated, but all proposals in

9 nificant advance in our understanding of the fundamental mechanisms associated with the entry of EAV

10 s to identify the elastic frustration as the fundamental mechanism at the origin of the very recent e

11 To investigate the fundamental mechanisms at the base of this conundrum--th

12 ncountered in climate model simulations, the fundamental mechanisms at the origin of sensitive behavi

13 A more fundamental mechanism based on metabolic cycles could th

14 s an ideal, simplified system to investigate fundamental mechanisms behind cellular self-organization

15 unique diagnostic to study the location and fundamental mechanisms behind emission processes.

16 The fundamental mechanisms behind this behaviour has not yet

17 aimed at improving our understanding of the fundamental mechanisms (both colloidal and noncolloidal)

18 cardiac genes during heart development and a fundamental mechanism by which a H3K27 demethylase trigg

19 Here, we describe a fundamental mechanism by which activation of the trp sup

20 ant signaling event in this process, yet the fundamental mechanism by which allergens induce Ca(2+) e

21 pecies (ROS)-induced ROS release (RIRR) is a fundamental mechanism by which cardiac mitochondria resp

22 A fundamental mechanism by which cells can give rise to da

23 Neuronal oscillations comprise a fundamental mechanism by which distant neural structures

24 These findings define a fundamental mechanism by which E. coli surpasses the hos

25 netic modifications of chromatin represent a fundamental mechanism by which eukaryotic cells adapt th

26 Together, our work describes a fundamental mechanism by which FOXC2 and oscillatory she

27 Increasing evidence suggests that this is a fundamental mechanism by which gliomas evade elimination

28 rated that bacterial flagellar motility is a fundamental mechanism by which host phagocytes bind and

29 However, the fundamental mechanism by which infectious prions are pro

30 in neurons to voltage itself may represent a fundamental mechanism by which ionotropic signals can sh

31 y and also increase our understanding of the fundamental mechanism by which Listeria spreads.

32 l has been elusive; this study defines a new fundamental mechanism by which oligodendroglia support n

33 larized vesicle trafficking has emerged as a fundamental mechanism by which protein and membrane can

34 tic Gs-coupled CRF receptors may represent a fundamental mechanism by which stress peptides and hormo

35 These data reveal a fundamental mechanism by which the hippocampus tempers t

36 he pathogenesis of psoriasis, representing a fundamental mechanism by which the IL-23-IL-17 axis medi

37 ntaneous emission of radiation is one of the fundamental mechanisms by which an excited quantum syste

38 Together, our observations shed new light on fundamental mechanisms by which chemotherapeutics may ki

39 of fluoride action and to the elucidation of fundamental mechanisms by which fluoride affects biomine

40 e for a useful model with which to study the fundamental mechanisms by which herpesvirus gH/gL regula

41 might make HCMV a useful model to study the fundamental mechanisms by which herpesvirus gH/gL regula

42 an exciting new avenue of research into the fundamental mechanisms by which inflammation impacts loc

43 ase Treg function and give insights into the fundamental mechanisms by which mitochondrial energy met

44 Our results provide insight into the fundamental mechanisms by which neural circuits can gene

45 DNA and histone proteins are now emerging as fundamental mechanisms by which neurons adapt their tran

46 ta reported here expand our knowledge on the fundamental mechanisms by which peptidyl transferase inh

47 go through. The hole closes." Studies of the fundamental mechanisms by which this process happens and

48 can greatly accelerate the understanding of fundamental mechanisms by which transcription, replicati

49 hi559, suggesting that ER stress could be a fundamental mechanism contributing to hepatic steatosis.

50 ation of AMPA receptor (AMPAR) function is a fundamental mechanism controlling synaptic strength duri

51 AP1-KIF5-dependent GABA(A)R trafficking is a fundamental mechanism controlling the strength of synapt

52 Deciphering the fundamental mechanisms controlling cardiac specification

53 Understanding these fundamental mechanisms depends on identifying the partic

54 Our observations suggest that the fundamental mechanisms do not give rise to two distinct

55 f signalling by retinoic acid as a conserved fundamental mechanism driving differentiation towards so

56 sults indicate that cellular senescence is a fundamental mechanism driving radiation-induced damage i

57 their expression have been proposed to be a fundamental mechanism driving the evolution of new body

58 The fundamental mechanisms driving evolution of the genetic

59 tial vanilloid 1 (TRPV1) through lipids is a fundamental mechanism during inflammation-induced periph

60 uggest that MNS-BVS interaction represents a fundamental mechanism explaining how nonverbal behavior

61 Our study reveals fundamental mechanisms facilitating the initial KT encou

62 Our results establish a fundamental mechanism for cell electrosensing and provid

63 suggesting they form part of an ancient and fundamental mechanism for cell polarization.

64 the actomyosin cytoskeleton that provides a fundamental mechanism for chiral morphogenesis in develo

65 eedback regulation of adaptive immunity is a fundamental mechanism for controlling the overall output

66 fic trafficking of arrestins may represent a fundamental mechanism for coordinating distinct GPCR-med

67 Localized protein synthesis is a fundamental mechanism for creating distinct subcellular

68 e calcium-sensing receptor (CaSR) provides a fundamental mechanism for diverse cells to detect and re

69 ube, dorsoventral signaling has emerged as a fundamental mechanism for generating neuronal diversity.

70 This cortical biasing may reflect a fundamental mechanism for integrating the auditory and v

71 nd amplitude correlations might constitute a fundamental mechanism for large-scale neural integration

72 t reflex (PLR) is our brain's first and most fundamental mechanism for light adaptation.

73 mitoyltransferase activity levels provides a fundamental mechanism for modulating palmitoylomes and c

74 release from synaptic vesicle fusion is the fundamental mechanism for neuronal communication at syna

75 ollowing synaptic vesicle (SV) fusion is the fundamental mechanism for neuronal communication.

76 These results reveal a fundamental mechanism for organizing the developing nerv

77 ory mechanism of Sema3 activity and define a fundamental mechanism for preferential Nrp binding.

78 restricted period of disinhibition may be a fundamental mechanism for receptive field plasticity, an

79 lving free-radical exchange, was used as the fundamental mechanism for reducing metal salts and dispe

80 fined regions within the cell cytoplasm is a fundamental mechanism for regulating cell and developmen

81 ggest that glutathionylation may represent a fundamental mechanism for regulating IP(3)R activity dur

82 acological desensitization of receptors is a fundamental mechanism for regulating the activity of neu

83 formational unbending represents a novel and fundamental mechanism for regulation of integrin-depende

84 generation in a variety of materials, but a fundamental mechanism for singlet fission has yet to be

85 g-standing materials issue suggests that the fundamental mechanism for superconductivity is the same

86 Loss of such synchrony could provide a fundamental mechanism for the degradation of acuity show

87 Protein interactions are a fundamental mechanism for the generation of biological r

88 num disulphide atomic layers and elucidate a fundamental mechanism for the nucleation, growth, and gr

89 on of autotroph biomass by heterotrophs is a fundamental mechanism for the transfer of nutrients and

90 ity fluctuations (oscillations) represents a fundamental mechanism for tuning the brain to the tempor

91 The fundamental mechanisms for forming the interfacial confi

92 Ca(2+) dynamics and oxidative signaling are fundamental mechanisms for mitochondrial bioenergetics a

93 ancestral parahoxozoans and imply that many fundamental mechanisms for the regulation of action pote

94 ticity of dendritic spines and synapses is a fundamental mechanism governing neuronal circuits and ma

95 sing multiphoton microscopy should now allow fundamental mechanisms governing development of the reti

96 To examine the fundamental mechanisms governing neural differentiation,

97 mental results raised the question about the fundamental mechanisms governing the electron-hole coupl

98 grammable DNA-binding proteins for which the fundamental mechanisms governing the search process are

99 The fundamental mechanism identified here for the efficient

100 iates exosome-cell interactions, revealing a fundamental mechanism important for exosome-mediated cro

101 sets should further our understanding of the fundamental mechanisms important for reactivation.

102 the regulation of gene expression, the most fundamental mechanism in biology, yet we still do not kn

103 of alterations in epigenetic regulators is a fundamental mechanism in cancer.

104 We propose that an underestimated albeit fundamental mechanism in teaching behavior is perceptual

105 Sirtuin pathways also modulate fundamental mechanisms in aging-related neurodegenerativ

106 d disease, and in using viruses to elucidate fundamental mechanisms in biology.

107 e methods for the intrinsic understanding of fundamental mechanisms in complex biochemical networks.

108 of technology, my laboratory has elucidated fundamental mechanisms in DNA replication, repair, and r

109 To address the fundamental mechanisms in these systems, we employed an

110 t nanoscale depths of cut to investigate the fundamental mechanisms in wafering of solar cells.

111 Biomolecular interaction is a fundamental mechanism involved in many critical biologic

112 ediated apoptosis of inflammatory cells is a fundamental mechanism involved in the resolution of eosi

113 They regulate fundamental mechanisms involved in the healing process i

114 h over the past several decades has revealed fundamental mechanisms involved in the initiation and ma

115 he molecular pathogenesis, has to target the fundamental mechanisms involved in the onset and progres

116 of such therapy can only be realised if the fundamental mechanisms leading to lethal cell damage und

117 These data reveal a fundamental mechanism linking nutrient and oxygen sensin

118 ing cell cycle progression could represent a fundamental mechanism linking oxidative metabolic proces

119 However, the fundamental mechanism linking ParA dynamics with regular

120 Such a fundamental mechanism may underlie the pleiotropic effec

121 pletely understood, in part because multiple fundamental mechanisms may contribute to the movement of

122 Our work demonstrates the fundamental mechanism necessary for using topological cr

123 Overall, we demonstrate the ability to study fundamental mechanisms necessary to optimize delivery an

124 ls by 5-HT-absorbing neurons may represent a fundamental mechanism of 5-HT homeostasis, integrating t

125 al microcrystals, enabling insights into the fundamental mechanism of action for the observed crystal

126 nt issue that remains unclear is whether the fundamental mechanism of activation of these genes is es

127 However, the fundamental mechanism of amyloid aggregation remains poo

128 The fundamental mechanism of antibody-mediated neutralizatio

129 een type I and type II ABC transporters, the fundamental mechanism of ATP hydrolysis remains conserve

130 Allostery represents a fundamental mechanism of biological regulation that is m

131 Allostery is a fundamental mechanism of biological regulation, in which

132 A fundamental mechanism of biphasic defibrillation was unc

133 en voltage- and Ca(2+)-sensing apparati is a fundamental mechanism of BK channel function.

134 ction through activation of p38, revealing a fundamental mechanism of cardiac dysfunction during insu

135 Ultimately, however, the fundamental mechanism of CD8 effector T cell differentia

136 e epithelial-mesenchymal transition (EMT), a fundamental mechanism of embryogenesis and progressive d

137 ion of DNA accessibility by nucleosomes is a fundamental mechanism of gene regulation in eukaryotes.

138 nd computational modeling to investigate the fundamental mechanism of gyrus formation.

139 ial mechanical systems, and they provide the fundamental mechanism of helical symmetry breaking.

140 essed this question for viral integration, a fundamental mechanism of horizontal gene transfer drivin

141 (V1V2), suggesting that SIV and HIV share a fundamental mechanism of immune escape from vaccine-elic

142 pal place-cell replay has been proposed as a fundamental mechanism of learning and memory, which migh

143 place cell sequences has been proposed as a fundamental mechanism of learning and memory.

144 preading depression (CSD) is thought to be a fundamental mechanism of migraine, and CSD in rodents is

145 Our revised BAM model proposes that the fundamental mechanism of mucosal immunity is subdiffusio

146 These results reveal a fundamental mechanism of neuronal phase-locking and high

147 e atmosphere has hindered elucidation of the fundamental mechanism of new-particle formation from gas

148 Understanding the fundamental mechanism of O2 reduction in aprotic solvent

149 BCs) in vivo holds the key to uncovering the fundamental mechanism of oxygen metabolism in cells.

150 Our observations reveal a fundamental mechanism of phloem formation and indicate t

151 Together, we demonstrate a fundamental mechanism of PIASy to localize in the centro

152 t clinical implication, because it targets a fundamental mechanism of post-ischemic cell death: intra

153 Covalent modification of histones is a fundamental mechanism of regulated gene expression in eu

154 cellular organelles in eukaryotic cells is a fundamental mechanism of regulating complex cellular fun

155 s in orientation and position, constitutes a fundamental mechanism of spatial navigation and a keysto

156 The fundamental mechanism of statin myopathy remains elusive

157 The system exploits a fundamental mechanism of stimuli-responsive deformation

158 Our results unveil a fundamental mechanism of T cell unresponsiveness differe

159 A fundamental mechanism of transcriptional regulation is h

160 r results underscore the conclusion that the fundamental mechanism of transmembrane signaling is cons

161 These calculations provide insight into the fundamental mechanism of tyrosyl radical generation, whi

162 further exploration and understanding of the fundamental mechanisms of abiotic stress responses.

163 Animal models provide a means to investigate fundamental mechanisms of abnormal electrical discharge

164 V channels and offer key insights into their fundamental mechanisms of action and differential therap

165 ling experimental platform for investigating fundamental mechanisms of adhesion-mediated cell signali

166 iting and dissociated it from stopping, both fundamental mechanisms of behavioral control.

167 hese studies supplement our knowledge of the fundamental mechanisms of bunyavirus infection and provi

168 yos and demonstrate unexpected plasticity to fundamental mechanisms of cell division.

169 several species, providing insights into the fundamental mechanisms of chromatin-mediated transcripti

170 The fundamental mechanisms of CMP are proposed according to

171 port in perovskite solar cells-which are the fundamental mechanisms of device operation and critical

172 Determination of fundamental mechanisms of disease often hinges on histop

173 s played an important role in uncovering the fundamental mechanisms of dislocation nucleation, but it

174 ular tools to more completely comprehend the fundamental mechanisms of fetal regenerative wound repai

175 Further, we show that the fundamental mechanisms of FLRT adhesion and repulsion ar

176 s atomically thin membranes, focusing on the fundamental mechanisms of gas- and liquid-phase transpor

177 results have implications for understanding fundamental mechanisms of gene expression.

178 These results provide insight into fundamental mechanisms of gene traffic control and point

179 robing the atomic-level understanding of the fundamental mechanisms of high-pressure torsion in metal

180 inhibitors drives the need to understand the fundamental mechanisms of how drug pressure-selected mut

181 ative, interdisciplinary strategy to dissect fundamental mechanisms of immune-cell interactions with

182 provide a rare yet powerful glimpse into the fundamental mechanisms of immunologic tolerance.

183 much knowledge has been generated about the fundamental mechanisms of inflammation.

184 This synthesis will provide an update on the fundamental mechanisms of inflammatory responses that go

185 hway that has great importance in describing fundamental mechanisms of intracellular albumin recyclin

186 ing efforts as well as for investigations of fundamental mechanisms of invasive disease and evolution

187 In this critical review, we discuss the fundamental mechanisms of laser GNP heat generation, the

188 to perceptual learning provides insight into fundamental mechanisms of learning and brain processes,

189 campal neurons, allowing novel insights into fundamental mechanisms of microtubule organization in ce

190 resents a valuable system for dissecting the fundamental mechanisms of modular polyketide biosynthesi

191 echnology advancements are required to study fundamental mechanisms of mRNA uptake and localization a

192 h as Drosophila and mouse has shown that the fundamental mechanisms of myogenesis are remarkably simi

193 es the involvement of progesterone and PR in fundamental mechanisms of neural development.

194 This work sheds light on fundamental mechanisms of neurotransmitter release.

195 Pigment patterns are useful for elucidating fundamental mechanisms of pattern formation and how thes

196 Direct structural insights on the fundamental mechanisms of permeation, selectivity, and g

197 Understanding the fundamental mechanisms of plant disease resistance is of

198 We discuss one of the fundamental mechanisms of protein homeostasis, the ubiqu

199 sis on patterned surfaces, for investigating fundamental mechanisms of receptor-mediated signaling in

200 evis is a powerful model system within which fundamental mechanisms of regeneration are being address

201 the yeast mip1 knockouts, suggesting common fundamental mechanisms of replication and conserved inte

202 he most recent advances in understanding the fundamental mechanisms of sepsis-induced AKI, characteri

203 To explore the fundamental mechanisms of such redox-coupled proton pump

204 Abeta generation and accumulation may affect fundamental mechanisms of synaptic plasticity.

205 Until recently, the fundamental mechanisms of temperature perception and sig

206 chanotransduction in ultrasound therapy, the fundamental mechanisms of these responses have not been

207 In this work, we explored the fundamental mechanisms of this structural transformation

208 Translation of the fundamental mechanisms of TNF superfamily is leading to

209 Although their catalytic cores and fundamental mechanisms of transcription elongation are c

210 ve led to the discovery of genes involved in fundamental mechanisms of transcription, translation, DN

211 ce for gene discovery and for unraveling the fundamental mechanisms of vertebrate embryogenesis.

212 Thus, differential deployment of a fundamental mechanism polarizing cellular growth contrib

213 Thus, differential deployment of a fundamental mechanism polarizing cellular growth contrib

214 The fundamental mechanism proposed to explain surface-enhanc

215 hydrogen peroxide microdomain signaling is a fundamental mechanism regulating arterial smooth muscle

216 onse to changes in intravascular pressure, a fundamental mechanism regulating blood flow to the brain

217 class IIa histone deacetylases (HDACs) is a fundamental mechanism regulating gene transcription.

218 Protein phosphorylation is a fundamental mechanism regulating nearly every aspect of

219 Visual evoked responses reveal changes in a fundamental mechanism regulating neuronal sensitivity.

220 (GPCR)-mediated presynaptic inhibition is a fundamental mechanism regulating synaptic transmission i

221 pmental disorders could provide insight into fundamental mechanisms regulating cell growth.

222 These results not only reveal fundamental mechanisms regulating DA neuron development,

223 or these processes have been identified, the fundamental mechanisms regulating SSC self-renewal and d

224 odel allow detailed analysis, and reveal the fundamental mechanism responsible for the phenomenon: th

225 sion and heart failure, and thus identifying fundamental mechanisms responsible for sympatholysis is

226 co-option of the polarity gene network is a fundamental mechanism shaping many aspects of plant morp

227 h spatiotemporal disorder resulting from two fundamental mechanisms - sources in preferred cardiac re

228 d external stimuli can be monitored; and the fundamental mechanisms such as cancer metastasis and ste

229 Macropinocytosis is a fundamental mechanism that allows cells to take up extra

230 LKB1/AMPK pathway, and this may represent a fundamental mechanism that contributes to cellular adapt

231 f distinct fates ('A', 'B') and constitute a fundamental mechanism that creates cell-type diversity i

232 nal cross-talk of PR-A with ER is probably a fundamental mechanism that enables metastasis of luminal

233 k alleles would be predicted to operate by a fundamental mechanism that influences the course of a nu

234 The sense of touch is a fundamental mechanism that nearly all organisms use to i

235 ing axillary meristem formation and define a fundamental mechanism that regulates inflorescence archi

236 flexor and extensor muscles constitutes the fundamental mechanism that tetrapod vertebrates use for

237 e over the course of lineage development are fundamental mechanisms that control cellular differentia

238 als, in the theoretical understanding of the fundamental mechanisms that control doping, and in the c

239 The fundamental mechanisms that control eukaryotic developme

240 Understanding the fundamental mechanisms that control hepatogenesis has al

241 se studies have, as a consequence, uncovered fundamental mechanisms that control mammalian gene expre

242 The fundamental mechanisms that control the self-bending beh

243 s and functional deficits in humans, but the fundamental mechanisms that drive ageing remain largely

244 of molecular insights that shed light on the fundamental mechanisms that drive the formation, growth,

245 Fusion transcript formation is one of the fundamental mechanisms that drives the development of pr

246 To begin to understand fundamental mechanisms that enable insects to cope with

247 document cellular phenotypic variation, the fundamental mechanisms that generate variability from id

248 However, the fundamental mechanisms that govern the interactions betw

249 Understanding the fundamental mechanisms that lead to the reduction of PTE

250 tive, these findings offer insights into the fundamental mechanisms that regulate male gametogenesis

251 The fundamental mechanisms that regulate the establishment a

252 ates both inflammation and fibrosis, yet the fundamental mechanisms that regulate these interactions

253 HA in distinct manners, which represents two fundamental mechanisms that the folding behavior of HA m

254 The fundamental mechanisms that underlie mt dysfunction in H

255 Here, we demonstrate that fundamental mechanisms, the reaction and diffusion of bi

256 f three MFS antiporters sheds light on their fundamental mechanism; they operate via a single binding

257 Although kin recognition is a fundamental mechanism through which cells might interact

258 Plasticity of glutamatergic synapses is a fundamental mechanism through which experience changes n

259 Microbial translocation may be a fundamental mechanism through which HIV accelerates prog

260 Activity-dependent neuronal plasticity is a fundamental mechanism through which the nervous system a

261 to the clock system have opened insight into fundamental mechanisms through which clocks program ener

262 More broadly, these data reveal fundamental mechanisms through which memory representati

263 ation of cysteine is now known to serve as a fundamental mechanism to control protein function or act

264 This work thus elucidates a fundamental mechanism to coordinate the activities of DN

265 itivity, and reduces frailty, targeting this fundamental mechanism to prevent age-related bone loss s

266 Differential gene expression is the fundamental mechanism underlying animal development and

267 Further, since SOCE is a fundamental mechanism underlying Ca(2+) signaling in mos

268 rected action control, which may represent a fundamental mechanism underlying compulsivity in obsessi

269 further suggest that the calcium trace is a fundamental mechanism underlying Drosophila LTM.

270 Our findings define a fundamental mechanism underlying eukaryotic cell fate di

271 We propose that the fundamental mechanism underlying resilience is the integ

272 However, the fundamental mechanism underlying such a strong light-mat

273 by airway dehydration alone and identifies a fundamental mechanism underlying the pathogenesis of CF

274 This work defines a fundamental mechanism underlying the specification of fa

275 The fundamental mechanism underlying these extremely prolong

276 Yet the fundamental mechanisms underlying alcohol-mediated brain

277 ation will provide crucial insights into the fundamental mechanisms underlying cancer progression and

278 To elucidate the fundamental mechanisms underlying carotenoid accumulatio

279 solution in vivo, may help shed new light on fundamental mechanisms underlying circuit development an

280 er of synthetic chemistry in elucidating the fundamental mechanisms underlying electronic polarizatio

281 es of complex neurological disorders and the fundamental mechanisms underlying health and disease.

282 nt, wound healing and tumorigenesis, but the fundamental mechanisms underlying intercellular coordina

283 ndings have important implications regarding fundamental mechanisms underlying neotissue formation; i

284 factory processing and provide insights into fundamental mechanisms underlying neuronal computations.

285 its receptor may play a critical role in the fundamental mechanisms underlying normal cortical develo

286 esults provide a deeper understanding of the fundamental mechanisms underlying sterile inflammation.

287 ovascular events and multiorgan failure, the fundamental mechanisms underlying the 'storage lesion' i

288 onsequently, there is a need to identify the fundamental mechanisms underlying the ageing process.

289 rovide a useful model system for deciphering fundamental mechanisms underlying the balance between pr

290 An understanding of the fundamental mechanisms underlying the development of epi

291 Our approach reveals fundamental mechanisms underpinning ligand regulation of

292 um-sensing systems have revealed some of the fundamental mechanisms underpinning the evolution of col

293 Methylation is a fundamental mechanism used in Nature to modify the struc

294 ved in nutrient acquisition and represents a fundamental mechanism used to remove pathogens and cellu

295 These studies have revealed fundamental mechanisms used by terrestrial animals for s

296 omputer simulation model to test whether two fundamental mechanisms-vesicle-coat-mediated selective c

297 ing, our results have potentially revealed a fundamental mechanism via which not only mechanical, but

298 The fundamental mechanism was modeled quantitatively and att

299 rt, lung, and brain, suggesting that it is a fundamental mechanism with implications for systemic S1P

300 exposure to chromatic modulation reveals two fundamental mechanisms with distinctive chromatic signat