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1 ement and movement of client substrates is a fundamental question.
2 on and its effect on transcription remains a fundamental question.
3 s activity in a large number of muscles is a fundamental question.
4  potentials) during human seizures remains a fundamental question.
5  recycle without apparent requirements, is a fundamental question.
6 es through a non-canonical pathway remains a fundamental question.
7 ic binding and synaptotoxicity have remained fundamental questions.
8  area of research comprising many unanswered fundamental questions.
9 eoning empirical literature, focusing on six fundamental questions.
10 -selective than the DEKA one are intriguing, fundamental questions.
11 lenging obstacles for researchers to address fundamental questions.
12 o the Mott insulating state raises important fundamental questions.
13              Despite substantial research, a fundamental question about its origin and links to intel
14                 This observation motivates a fundamental question about the evolution of any sensory
15      The nature of this information raises a fundamental question about these face-selective areas: D
16 new protocol should be useful for addressing fundamental questions about antigen-specific memory B ce
17  models have great potential to address many fundamental questions about brain function, providing an
18                                However, many fundamental questions about cancer-associated VTE, or Tr
19                                              Fundamental questions about circulating viruses and tran
20 ial therapeutic applications, and to address fundamental questions about control of cell identity, mo
21                                         Many fundamental questions about EBS remain unanswered, inclu
22 ounds will continue to provide insights into fundamental questions about how aromatic compounds behav
23 surface geology and long-term activity raise fundamental questions about how small planets remain act
24     These multiple effects shed new light on fundamental questions about LC8-containing complexes and
25 phylogenetic research has still not resolved fundamental questions about leaves.
26  lineage and regulators for the progenitors, fundamental questions about mechanisms driving expansion
27                                  This raises fundamental questions about mechanisms of non-redundancy
28 olic models have proven useful for answering fundamental questions about metabolic capabilities of a
29 aded for the donor's stage of AMD to address fundamental questions about mtDNA damage in the retina.
30                        This discovery raises fundamental questions about new atomistic mechanisms gov
31 of cholesterol has been intensively studied, fundamental questions about oxysterols, such as their su
32 l. (2017) and Warfield et al. (2017) revisit fundamental questions about SAGA and TFIID function in y
33        The existence of these sensors raises fundamental questions about self/nonself discrimination
34 downstream from the N-terminus, which raises fundamental questions about targeting and assembly.
35 cuss how this technology can help to address fundamental questions about the adult stem cell niche.
36                           However, to answer fundamental questions about the behavior of biological s
37                                     However, fundamental questions about the branching structure of L
38  identified a neural marker for unique hues, fundamental questions about the contribution of neural h
39 dult injured CNS is not well defined, posing fundamental questions about the design and implementatio
40 nsport rates are unexpectedly high and raise fundamental questions about the details of the transport
41                         The study raises new fundamental questions about the function of vibrational
42 sues and can be used to address a variety of fundamental questions about the genomes of diseased tiss
43 ld equally great promise for helping address fundamental questions about the mechanisms or the conseq
44       We conclude that scientists can tackle fundamental questions about the nature and appreciation
45 omic techniques have brought data to bear on fundamental questions about the nature and extent of ple
46                                     However, fundamental questions about the nature of doping in thes
47 ly minor effects on synapse numbers, raising fundamental questions about the overall physiological ro
48 2013) and one by Tata et al. (2013), address fundamental questions about the universality of reparati
49 spite their relative abundance in the brain, fundamental questions about their function, heterogeneit
50 pened up new possibilities for tackling many fundamental questions about this important immunologic p
51                              One of the most fundamental questions about this phenomenon involves the
52 the absence of emotional input, addressing a fundamental question and opening a path to future therap
53        These results resolve a long-standing fundamental question and suggest the existence of a codo
54 far as the answers it offers to a variety of fundamental questions and concerns; as such, those who p
55 owed the study of oxidative stress to tackle fundamental questions and have provided several conceptu
56          At first glance, the answer to this fundamental question appears straightforward: spatial in
57 ian clocks than other organisms, inspiring a fundamental question: are all these regulatory interacti
58 y endosomal sorting stations, which raises a fundamental question: are SVs sorted toward endolysosoma
59                              This raises the fundamental question as to how these PDZ domains discrim
60 sexually dimorphic gonads are generated is a fundamental question at the interface of developmental a
61             The present paper addresses this fundamental question by examining the face-centered-cubi
62                            We addressed this fundamental question by taking advantage of optogenetics
63                            We addressed this fundamental question by taking advantage of optogenetics
64 for comprehensive answers to these and other fundamental questions by connecting the physiological an
65 enomenal success of these catalysts, several fundamental questions central to their reactivity remain
66                                            A fundamental question centres on the feeding interactions
67 iofilm structure and hydrodynamics remains a fundamental question concerning biofilm dynamics.
68 embrane proteases have been solved recently, fundamental questions concerning mechanistic underpinnin
69 ional characterization of the Hsp70 proteins fundamental questions concerning modularity of the allos
70                       This phenomenon raises fundamental questions concerning photon transport throug
71                                  This raises fundamental questions concerning the effects of thermal
72                                              Fundamental questions concerning the informational conte
73                                              Fundamental questions concerning the structure of the ve
74 e seen, laying the foundation for addressing fundamental questions concerning the taxa comprising div
75                                       Thus a fundamental question concerns the stability versus flexi
76                                          One fundamental question concerns whether the hippocampus re
77 oad expansion of ePK families have made this fundamental question difficult to answer.
78                          As answers to these fundamental questions emerge, all biologists will be cha
79 orms and flies and provides insight into the fundamental questions facing this field.
80 are typically pursued in isolation, but many fundamental questions fall squarely at the interface of
81                     This illusion raises two fundamental questions: first, given the incongruence bet
82 maintenance of complex biological shape is a fundamental question for cell, developmental, and evolut
83 s differ in their evolutionary dynamics is a fundamental question for historical and comparative ling
84 lized transcription factor (TF) cascade is a fundamental question for understanding cell-cycle regula
85  unpaired stimuli is poorly understood and a fundamental question for understanding the signalling me
86                               Resolving this fundamental question has been difficult because it requi
87                                            A fundamental question has been how a cell can assemble an
88                                          One fundamental question has been whether germ cells are reg
89  While advances have been plentiful, several fundamental questions have yet to be answered and much c
90       Overall, this now leads the field to a fundamental question: how can this divergence be justifi
91 over their code, clarifying perhaps the most fundamental question: how they modulate immune surveilla
92                           We address several fundamental questions: how can enabling environments and
93         All these studies strive to answer a fundamental question: "how do living systems probe and r
94 rceptual decision making revolves around two fundamental questions: (i) How are the neural representa
95 hance neuroplasticity, our ACM addresses two fundamental questions: (i) what are the proximate and ul
96       We use this framework to address three fundamental questions: (i) when a cell should prefer thr
97 ingle-molecule spectroscopy, we address this fundamental question in a model material, poly(3-hexylth
98 mote cooperative or altruistic behavior is a fundamental question in biological and social sciences.
99                                            A fundamental question in biology is how sharp boundaries
100                                            A fundamental question in biology is the following: what i
101 teins have evolved their functions remains a fundamental question in biology.
102 n fold have evolved different functions is a fundamental question in biology.
103  and DNA sites in paralogous regulators is a fundamental question in biology.
104 ge from one generation to the next remains a fundamental question in biology.
105 n contributes to phenotypic differences is a fundamental question in biology.
106                       Metabolomics answers a fundamental question in biology: How does metabolism res
107 s in patients and strive to proliferate is a fundamental question in cancer biology.
108  defined length and lumen diameter remains a fundamental question in cell and developmental biology.
109                                      It is a fundamental question in cell biology and biophysics whet
110                                            A fundamental question in cell biology concerns the regula
111                                            A fundamental question in cell biology is how the sizes of
112 ct recycling pathways from the endosome is a fundamental question in cell biology.
113  gradient for biological functions remains a fundamental question in cell biology.
114 ute structurally to centromere function is a fundamental question in chromosome biology.
115                                            A fundamental question in cognitive neuroscience is how th
116                                            A fundamental question in development is how cells assembl
117                                            A fundamental question in developmental biology is whether
118 ols diverse programs of gene expression is a fundamental question in developmental biology.
119 ft-right (LR) axis is first established is a fundamental question in developmental biology.
120                                            A fundamental question in developmental neuroscience is ho
121  cortical interneurons behave similarly is a fundamental question in developmental neuroscience.
122                                            A fundamental question in DMD pathogenesis and dystrophin
123 ons while others fail to even establish is a fundamental question in ecology.
124 aits and contributes to their variation is a fundamental question in evolution and human genetics.
125 s in the radiation of species diversity is a fundamental question in evolutionary biology.
126                          A long-standing but fundamental question in lightning studies concerns how l
127                         This is a study of a fundamental question in neurobiology: how are signals pr
128 ints on our capacity for sensory uptake is a fundamental question in neuroscience.
129                                            A fundamental question in protein folding is whether prote
130                                            A fundamental question in protein folding is whether the c
131                                            A fundamental question in sensory neuroscience is how para
132 mechanisms of these characteristics remain a fundamental question in stem cell biology.
133              How movements are selected is a fundamental question in systems neuroscience.
134                                            A fundamental question in the study of chemical reactions
135                                            A fundamental question in the study of human language acqu
136                                            A fundamental question in these diseases is the extent inf
137                                            A fundamental question in this debate involves quantifying
138                                          One fundamental question in tubule formation is how individu
139                                            A fundamental question in vaccine design is the extent to
140                                            A fundamental question in vision neuroscience is how the v
141 n of bimodal (mafic-felsic) rock suites is a fundamental question in volcanology.
142 d to yield adequate data required to address fundamental questions in archaeology and biology.
143                              One of the most fundamental questions in behavioural biology is why soci
144                            Three of the most fundamental questions in biology are how individual cell
145                              One of the most fundamental questions in biology is that of biological p
146 esented approach allows the investigation of fundamental questions in biology such as the evolution o
147 h new research efforts to address one of the fundamental questions in cancer biology-why are some cel
148 cule technology has the potential to address fundamental questions in chromatin biology and epigeneti
149 itative analysis, is ideal for investigating fundamental questions in developmental biology involving
150  implementation of this framework to address fundamental questions in ecology relating to climate cha
151                                        These fundamental questions in electronic structure theory, wh
152 how such approaches are being used to answer fundamental questions in embryology, such as how cells s
153                                         Many fundamental questions in evolutionary biology entail est
154                              One of the most fundamental questions in evolutionary biology is the ori
155 ng have made it possible for these and other fundamental questions in evolutionary biology to be addr
156 ucidate the origins of cooperation and other fundamental questions in evolutionary biology.
157 fish ear bones (otoliths) is used to address fundamental questions in fish ecology and fisheries scie
158 magnetic stimulation), we here address these fundamental questions in human participants performing a
159 g diverse and specialized species to address fundamental questions in mammalian biology.
160 of similar form is used routinely to address fundamental questions in morphofunctional research and t
161 city, and gene expression, thereby answering fundamental questions in neurobiology.
162 Is also represent a powerful tool to address fundamental questions in neuroscience.
163                           They contribute to fundamental questions in plant biology and may have prac
164 ed to plants, and their potential to address fundamental questions in plant biology.
165 ways are integrated with other inputs remain fundamental questions in plant biology.
166                                 However, the fundamental questions in regards to fMRI technology: how
167                              One of the most fundamental questions in the control of gene expression
168                                   One of the fundamental questions in the field of LTP is why differe
169                  We therefore show that some fundamental questions in this area cannot be answered by
170                               Among the most fundamental questions in viral evolutionary biology are
171 iations, can focus on and resolve answers to fundamental questions, including protonation and/or H-bo
172                                            A fundamental question is how autophagosome formation is r
173                                          One fundamental question is how CSL can recognize and select
174                                            A fundamental question is how generalist pollinators recog
175                                            A fundamental question is how hydrophilic nanostructures r
176            Given this enormous complexity, a fundamental question is how is this achieved?
177                                          One fundamental question is how these friction effects depen
178                                A natural and fundamental question is then whether there are yet-to-be
179                                            A fundamental question is what role the pyrite surface pla
180                                          One fundamental question is whether individual bacterial cel
181                                   However, a fundamental question is whether stochastic gene expressi
182 using linear-threshold-based dynamics, and a fundamental question is whether the individuals in such
183                                            A fundamental question is whether these comparatively low
184                                            A fundamental question is whether toxicity is driven by th
185                                            A fundamental question is, how fast can the magnetization
186                                          One fundamental question is: are all these alternative splic
187 ct factors to short-term citations, raises a fundamental question: Is there long-term predictability
188           In this work, we seek to address a fundamental question linking biology and nonequilibrium
189                                      Several fundamental questions need to be addressed about enhance
190                                          The fundamental question of how bone quality is affected in
191 ss in understanding biofilm development, the fundamental question of how cells sense the environmenta
192 nearest neighbours are observed, and poses a fundamental question of how complex interactions on the
193 perated calcium entry (SOCE) regulation, the fundamental question of how ER morphology affects this p
194                                 However, the fundamental question of how force regulates actin dynami
195                           To investigate the fundamental question of how nervous systems encode, orga
196 The current study was designed to answer the fundamental question of how such NPs are distributed in
197 eviously reported, and address the important fundamental question of how the work function of small s
198 cially valuable platforms for addressing the fundamental question of how to reverse the adverse bioch
199 sequence databases has increasingly made the fundamental question of searching for homologs a computa
200 ls that provide long-lived immunity, but the fundamental question of when and how these cells arise r
201 entury, there has been disagreement over the fundamental question of whether "emotions" are cause or
202 ivated by individual stresses, provoking the fundamental question of whether and how cells control th
203                              This raises the fundamental question of whether HSCs and restricted prog
204                                          The fundamental question of whether human telomerase catalyt
205  genome functions across eukaryotes, but the fundamental question of whether nucleosomal or naked DNA
206                              This raises the fundamental question of whether signaling pathways have
207 ions and outer hair cell (OHC) motility, the fundamental question of whether the cochlea produces mec
208                              This raises the fundamental question of whether the ICR plays a species-
209                                          The fundamental question of which genes are most important i
210                            Surprisingly, the fundamental question of which species of the conjugate p
211 of cell wall synthesis processes, to address fundamental questions of bacterial cell wall biogenesis.
212 s may provide tools with the scope to answer fundamental questions of cell communication and initiate
213  enabled developmental biologists to address fundamental questions of developmental gene regulation o
214 at these were ideal model organisms to study fundamental questions of energy conservation, CO2 fixati
215 r genetic structures and functions to answer fundamental questions of life.
216 opportunities, not only in understanding the fundamental questions of nanoparticles but also in openi
217 on the use of droplet ensembles to look into fundamental questions of non-equilibrium systems, such a
218 y costs from phenotype costs, we re-evaluate fundamental questions of the limits to the evolution of
219 a, in human health have sought to answer the fundamental questions of what organisms are present, how
220 imulating methods and protocols, raising the fundamental questions of what precise physical stimulus
221 s also continuing disagreement over the more fundamental questions of which cortical layers generate
222                                          The fundamental question on pathogenesis of pseudoxanthoma e
223  providing an alternative approach to tackle fundamental questions on circuit remodeling.
224                                     However, fundamental questions on whether TrkH is an ion channel
225 skepticism but have also brought up numerous fundamental questions pertaining to the distinguishabili
226                                   One of the fundamental questions posed by these rhythms is how indi
227                                We comment on fundamental questions raised by this new finding and the
228 olution, and provides a basis for addressing fundamental questions, ranging from protein sorting in t
229                                            A fundamental question regarding the thermal and mechanica
230  provide experimental results that address a fundamental question regarding these selective pressures
231             This microalloying effect raises fundamental questions regarding creep deformation mechan
232 numerous studies of malaria pathophysiology, fundamental questions regarding hematin growth and inhib
233                Yet despite its significance, fundamental questions regarding how the sulfide oxidatio
234   Projects within the consortium will answer fundamental questions regarding human gene expression in
235 mplications for future studies in unraveling fundamental questions regarding origins and evolution of
236 ed fragment sequencing (SLAF-seq) to address fundamental questions regarding soybean domestication.
237  to genetic instability but also address the fundamental questions regarding stacking of G-quadruplex
238 This system offers an opportunity to explore fundamental questions regarding the effect of protein cr
239                           Its finding raised fundamental questions regarding the effects of pressure
240            In this critical review, the open fundamental questions regarding the interactions of cell
241 achieved through answering and understanding fundamental questions regarding the observed physical pr
242 doption of Tg techniques will help to answer fundamental questions regarding the pathogenesis of hepa
243               Together, these features raise fundamental questions regarding the regulation of circRN
244                                         Many fundamental questions regarding the substrate specificit
245 maintenance of glycoprotein quality control, fundamental questions regarding this enzyme remain contr
246                                              Fundamental questions regarding where, when, and how man
247 mulation and modeling studies addressing two fundamental questions regarding zwitterionic materials a
248    Despite decades of research in this area, fundamental questions related to how neuron density and
249 hanisms behind methylation is limited due to fundamental questions related to the geochemical forms o
250 e molecular regulation of lipophagy, discuss fundamental questions related to the mechanisms by which
251                                     However, fundamental questions relating to the structural basis o
252     The details of ion hydration still raise fundamental questions relevant to a large variety of pro
253  localize to specific subcellular locations, fundamental questions remain about how cellular-scale st
254                                         Many fundamental questions remain about how these proteins or
255                                              Fundamental questions remain about how transporters tran
256 lity to choose the relevant information, but fundamental questions remain about the brain's informati
257 s from another (Australopithecus afarensis), fundamental questions remain about the evolution of huma
258                                              Fundamental questions remain about the origin of newly f
259  due to their slow in situ growth rates, and fundamental questions remain about their ecology and div
260 nges for modern science, yet answers to many fundamental questions remain elusive.
261                                              Fundamental questions remain however regarding the exten
262 etween the human microbiome and disease, yet fundamental questions remain on how we can generalize th
263                                     However, fundamental questions remain regarding how priors are le
264                                     However, fundamental questions remain unanswered about the epigen
265                                    Paramount fundamental questions remain unanswered that require an
266        Although alternative models exist and fundamental questions remain unanswered, a definitive de
267                                However, many fundamental questions remain unanswered.
268                                              Fundamental questions remain, however, regarding how thi
269 ding to channel opening have been described, fundamental questions remain, including the functional s
270 ability to prevent and treat influenza, many fundamental questions remain, including those related to
271                                              Fundamental questions remain, such as how the flexibilit
272 n resolving the vertebrate tree of life, two fundamental questions remain: 1) what is the phylogeneti
273  peripheral blood of psychiatric patients, a fundamental question remains as to whether epigenetic ma
274 t of underlying neurobiological processes, a fundamental question remains unanswered: Is cognition a
275 ompared to the conventional formulation, the fundamental question remains whether they also improve a
276  features of mature photoreceptor cells, the fundamental question remains whether transplantation of
277                                            A fundamental question remains: does reduced degradation o
278  of eyespots in deterring predator attack, a fundamental question remains: Given their protective ben
279                                            A fundamental question remains: Why is airway tolerance co
280 Fs an exceptionally powerful tool to address fundamental questions responsible for chemical behavior
281                              To address such fundamental questions, several techniques for clonal lab
282 imental and theoretical efforts, some of the fundamental questions such as degree of 5 f-electron loc
283 these interactions, comprehensive answers to fundamental questions, such as how resource availability
284 ms will be required to address the remaining fundamental questions surrounding the enigma that is BV.
285 enorhabditis elegans embryos to address this fundamental question, testing three potential mechanisms
286  the presence of metabolic fluctuations is a fundamental question that has not been fully answered.
287                                            A fundamental question that has puzzled researchers for de
288                                          The fundamental questions that GPMs address involve making d
289 ing the possible future directions, from the fundamental questions that remain to be addressed to the
290                       Moreover, we highlight fundamental questions that should be addressed in future
291 ses on progress toward answers for the three fundamental questions that sit at the heart of the pRB l
292                             To address these fundamental questions we exploited a transchromosomic an
293                              To address this fundamental question, we extended the temporal resolutio
294                              To address this fundamental question, we visualized microtubule-bound ki
295                    In order to address these fundamental questions, we designed and implemented a new
296 orks with known stoichiometry to address the fundamental question: "What can causal networks tell us
297                       This review explores a fundamental question: 'what are the specific criteria th
298                             Answering such a fundamental question will expand our understanding of th
299 ir progeny that seed the thymus constitute a fundamental question with important clinical implication
300  diversity is generated is a fascinating and fundamental question with important clinical implication

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