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1  vitreous, macular atrophy, and a tesselated fundus.
2 tect retinopathy before it is visible in the fundus.
3  glomerulonephritis was associated with more fundus abnormalities and a screening SDOCT should be con
4                                       Ocular fundus abnormalities characteristic of pseudoxanthoma el
5 tation, best-corrected visual acuity (BCVA), fundus abnormalities, visual field defects, ffERG change
6      All participants underwent quantitative fundus AF (qAF) imaging with a modified scanning laser o
7 ample showed no increased lipofuscin-related fundus AF in patients with early and intermediate AMD.
8 onal diversity among neurons in the anterior fundus (AF) face patch, combining whole-brain fMRI with
9 f the phenotypes predicted by an MDR result (fundus albipunctatus due to RDH5 and variegate porphyria
10 stimulation (EVS) were recorded from gastric fundus and antral regions of wild type and W/W(V) mice,
11 human gastric epithelial cells of the corpus/fundus and in HGT-1 cells, a model for the study of GAS.
12         The severity of the various ischemic fundus and retinal lesions and of the optic disc during
13 n aged 20 years was asymptomatic with normal fundus and SD OCT (stage 0).
14 el for studying the development of the human fundus and the molecular bases of human gastric physiolo
15                                          The fundus and the optic disc were evaluated by repeated oph
16                                  Fluorescein fundus angiography soon after cutting the PCAs showed no
17 py, color fundus photography and fluorescein fundus angiography, before and immediately after cutting
18              Visual symptoms, visual acuity, fundus appearance, and the presence and characteristics
19 A variants, age at diagnosis, visual acuity, fundus appearance, visual field, and full-field electror
20 -invasive, human clinical testing, including fundus auto-fluorescence, optical coherence tomography,
21 n area of increased autofluorescence on blue fundus autofluorescence (B-FAF).
22 he enlargement of the atrophic lesions using fundus autofluorescence (FAF) and color fundus photograp
23 coherence tomography (OCT), OCT-Angiography, fundus autofluorescence (FAF) and fluorescein-angiograph
24 jective corroboration for visual fields, and fundus autofluorescence (FAF) can show damage topographi
25                                              Fundus autofluorescence (FAF) decays were detected in sh
26                       Eyes were evaluated on fundus autofluorescence (FAF) for GA.
27              The 200 degrees pseudocolor and fundus autofluorescence (FAF) images were captured on th
28 acula volume scans centered at the fovea and fundus autofluorescence (FAF) images were obtained.
29 sed primarily by color fundus photography or fundus autofluorescence (FAF) imaging.
30 ain optical coherence tomography (SDOCT) and fundus autofluorescence (FAF) imaging.
31 in optical coherence tomography (SD OCT) and fundus autofluorescence (FAF) imaging.
32 omain optical coherence tomography (SD OCT), fundus autofluorescence (FAF), and fluorescein angiograp
33 with conventional multimodal imaging (color, fundus autofluorescence (FAF), and infrared reflectance
34 omain optical coherence tomography (SD-OCT), fundus autofluorescence (FAF), and infrared reflectance
35 ear-infrared (NIR) and short-wavelength (SW) fundus autofluorescence (FAF), and NIR reflectance (REF)
36 ude color fundus photography (CFP), confocal fundus autofluorescence (FAF), confocal near-infrared re
37 plete ophthalmological examination including fundus autofluorescence (FAF), dynamic simultaneous fluo
38 omain optical coherence tomography (SD OCT), fundus autofluorescence (FAF), or multifocal electroreti
39  visits for at least 1 examination modality: fundus autofluorescence (FAF), spectral-domain (SD) opti
40                                 Quantitative fundus autofluorescence (qAF) and spectral-domain optica
41 ndus lesions by quantifying short-wavelength fundus autofluorescence (quantitative fundus autofluores
42 nce tomography (SD-OCT) and short wavelength fundus autofluorescence (SW-AF).
43 aluate the disease extent on ultra-widefield fundus autofluorescence (UWF-FAF) in patients with ABCA4
44 [SD] optical coherence tomography [OCT], and fundus autofluorescence [FAF]) then were reviewed.
45 length fundus autofluorescence (quantitative fundus autofluorescence [qAF]) and spectral-domain optic
46                                              Fundus autofluorescence and electrophysiological testing
47 derwent best-corrected visual acuity (BCVA), fundus autofluorescence and spectral domain-optical cohe
48 ering) could produce a cross-shaped increase fundus autofluorescence artifact on subsequent imaging.
49 ng system of SC lesions based on SS-OCTA and fundus autofluorescence findings.
50 east 1 eye at the most recent visit, and (2) fundus autofluorescence images for at least 2 visits wit
51                                A series of 3 fundus autofluorescence images using 3 different acquisi
52  these patients, 215 had at least 2 gradable fundus autofluorescence images with atrophic lesion(s) p
53 tofluorescent AZOOR line in short-wavelength fundus autofluorescence images, delineating the peripapi
54                                              Fundus autofluorescence imaging and optical coherence to
55 elength reduced-illuminance and conventional fundus autofluorescence imaging showed good concordance
56 eld electroretinography, fundus photography, fundus autofluorescence imaging, and optical coherence t
57  clinically by wide-field color photography, fundus autofluorescence imaging, and spectral-domain opt
58  fundus examination, wide-field photography, fundus autofluorescence imaging, sedated electroretinogr
59  produced a striking leopard-spot pattern on fundus autofluorescence imaging.
60 ated with marked loss of autofluorescence on fundus autofluorescence imaging.
61 ve on NIR reflectance and hypofluorescent on fundus autofluorescence imaging.
62        The dots were hyperautofluorescent on fundus autofluorescence imaging.
63 main optical coherence tomography (OCT), and fundus autofluorescence imaging.
64 ents with Stargardt disease as determined by fundus autofluorescence imaging.
65 n area was larger than both the ONL-slab and fundus autofluorescence lesion areas.
66      In Stargardt disease with DDAF lesions, fundus autofluorescence may serve as a monitoring tool f
67         Interestingly, no changes in macular fundus autofluorescence pattern were evident after optic
68 CI, 0.42-0.61 mm2/y), and of total decreased fundus autofluorescence was 0.35 mm2/y (95% CI, 0.28-0.4
69 f patients exhibiting annular RPE lesions on fundus autofluorescence was included for chart review an
70 ptic nerve head (ONH), infrared reflectance, fundus autofluorescence, and color fundus photographs (C
71  color photography, fluorescein angiography, fundus autofluorescence, and high-resolution optical coh
72 l field, and full-field electroretinography, fundus autofluorescence, and optical coherence tomograph
73                    Color fundus photographs, fundus autofluorescence, and spectral-domain OCT were ob
74 o short-wavelength light resulted in reduced fundus autofluorescence, decreased HPLC-quantified A2E,
75 reen angiography, near-infrared reflectance, fundus autofluorescence, high-resolution OCT, and ultraw
76                     Other methods, including fundus autofluorescence, near-infrared reflectance, and
77 graphy (OCT), en face near-infrared imaging, fundus autofluorescence, optical coherence tomography an
78  diameter of a paracentral ring of increased fundus autofluorescence.
79 cidence of atrophic lesions as determined by fundus autofluorescence.
80 t, visibility on funduscopy, ultrasound, and fundus autofluorescence.
81 g the growth of atrophic lesions measured by fundus autofluorescence.
82 idenced by HPLC analysis and quantitation of fundus autofluorescence; this effect is consistent with
83 , using a nonmydriatic, autofocus, hand-held fundus camera (Volk Optical, Mentor, Ohio, USA).
84                    A portable, nonmydriatic, fundus camera can facilitate remote evaluation of disc i
85 aken with a portable, 45-degree nonmydriatic fundus camera to images from a traditional tabletop mydr
86 g involves examining HEs qualitatively using fundus camera.
87 images from a traditional tabletop mydriatic fundus camera.
88 easure the area of HEs in the digital colour fundus (CF) photographs.
89 anges were older than patients without these fundus changes (two studies).
90 ause they are at risk of developing PXE-like fundus changes and potentially of subsequent choroidal n
91                Pseudoxanthoma elasticum like fundus changes are a frequent finding in patients with b
92 lar tortuosity independently of the PXE-like fundus changes was found in 11-17.9 % (three studies), w
93                       Patients with PXE-like fundus changes were older than patients without these fu
94 ongest association with presence of PXE-like fundus changes.
95                                              Fundus characteristics included abnormal collapsed vitre
96                      Data gathering included fundus color photographs, fluorescein angiography, spect
97 ination; automated visual field testing; and fundus color photography.
98 ght sensitivity of the macula in STGD1 using fundus-controlled perimetry (microperimetry).
99 retinal imaging in combination with scotopic fundus-controlled perimetry allows for a more refined st
100                         Scotopic and mesopic fundus-controlled perimetry was performed in patients.
101  then recapitulating key events in embryonic fundus development.
102 ut the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tool
103                   Review of clinical charts, fundus drawings, Ret-Cam 3 images, and histopathology sp
104     To revisit the autosomal dominant Sorsby fundus dystrophy (SFD) as a syndromic condition includin
105 m patients with three dominant MDs, Sorsby's fundus dystrophy (SFD), Doyne honeycomb retinal dystroph
106 re few adequate models in which to study the fundus epithelium of the human stomach.
107  more widespread injury than is suggested by fundus examination (two studies).
108 gates exhibited lower inflammatory scores by fundus examination and a slower initial rate of loss of
109                               Results of the fundus examination and of SW-FAF and NIR-FAF imaging wer
110 , which could not be distinguished either on fundus examination or by spectral domain optical coheren
111 ith acute visual field loss despite a normal fundus examination performed at a university teaching ho
112                                           On fundus examination PEVAC presented as a large perifoveal
113                                              Fundus examination revealed chorioretinal atrophy of the
114                                              Fundus examination revealed midperipheral retinal pigmen
115                                              Fundus examination revealed peripheral hemorrhagic retin
116                                   A baseline fundus examination should be performed to rule out preex
117                                              Fundus examination showed pale retina with no cherry red
118                                              Fundus examination was characterized by severe bullous r
119 lar degeneration (AMD) or retinal disease at fundus examination were matched for each patient with EM
120 sment, intraocular pressure measurement, and fundus examination were performed each time.
121 uded Snellen-measured visual acuity, dilated fundus examination, and spectral-domain optical coherenc
122 nt best-corrected visual acuity measurement, fundus examination, and spectral-domain optical coherenc
123 mologic examination was performed, including fundus examination, FA, and OCTA.
124                                           On fundus examination, left optic disc margin was blurred.
125 ual acuity, slit-lamp biomicroscopy, dilated fundus examination, wide-field photography, fundus autof
126 e and near visual acuity evaluation; dilated fundus examination; OCT with 12 x 6-mm thickness map; ho
127 , clinical findings of slit-lamp and dilated fundus examinations.
128 c objective refraction, slit lamp as well as fundus examinations.
129 ma-associated retinopathy with unanticipated fundus findings while receiving treatment with the immun
130 angerous variant identified at VR induced a "fundus first" approach.
131 retinitis pigmentosa, pattern dystrophy, and fundus flavimaculatus in the same family.
132 retinography (ERG), fundus photography (FP), fundus fluorescein angiography (FFA), and optical cohere
133 ed on optical coherence tomography (OCT) and fundus fluorescein angiography.
134                                              Fundus fluorescence angiography was done whenever necess
135                                              Fundus hemorrhages are common among newborns.
136                                              Fundus hemorrhages were more common in the left eye than
137                                              Fundus hemorrhages were most commonly optic nerve flame
138  common reasons for referral were ungradable fundus image (39.3% of those referred), best-corrected V
139 conventional AAV2 in GFP expression based on fundus image analysis and qRT-PCR.
140 p, highlighting subregions within each input fundus image for further clinical review.
141  (e-ROP) Study telemedicine system of remote fundus image grading and The Children's Hospital of Phil
142 feature after registering the macular ocular fundus image to the peripapillary ocular fundus image.
143 lar fundus image to the peripapillary ocular fundus image.
144       Retinopathy was evaluated from digital fundus images (2002-2006) using the modified Airlie Hous
145 d strengths of both the remote evaluation of fundus images and bedside clinical examination of infant
146                The algorithm processed color fundus images and classified them as healthy (no retinop
147  in the study, 9962 (99.3%) who had gradable fundus images and Visual Function Index (VF-11) data ava
148 usen (RPD) was assessed by masked grading of fundus images and was confirmed with optical coherence t
149 rning-based automated assessment of AMD from fundus images can produce results that are similar to hu
150 tic red-free monochromatic 60-degree digital fundus images centered on the macula and optic disc of 2
151         A total of 75 137 publicly available fundus images from diabetic patients were used to train
152 nts were at risk for developing AMD based on fundus images obtained at baseline visits.
153                    Three hundred thirty-five fundus images of prematurely born infants were obtained
154 d in 2007 and 2016 to classify 34 wide-field fundus images of ROP as plus, pre-plus, or normal, coded
155 methods for automatically detecting AMD from fundus images using a novel application of deep learning
156                                              Fundus images were graded for AMD using the Wisconsin Ag
157                                              Fundus images were graded using the International Classi
158 patients with type 1 diabetes and ungradable fundus images, 361 participants were included in the ana
159 OP]) was developed using a set of 77 digital fundus images, and the system was designed to classify i
160 PE- defects in patients with AMD using Color fundus images, Optical coherence tomography (OCT), OCT-A
161                                              Fundus images, taken using a digital camera through dark
162 that do not require subjective evaluation of fundus images.
163 al filtering, and thresholding of the colour fundus images.
164 y on phenotypical characteristics from color fundus images.
165 FP expression was noninvasively monitored by fundus imaging and retinal expression was analyzed 4 wee
166 edly suppressed angiogenesis as evaluated by fundus imaging in aged Ins2(Akita) mice even after 3mont
167 t are not generally visible with traditional fundus imaging modalities.
168 ll participants underwent color, FAF, and IR fundus imaging, as well as imaging with a prototype Zeis
169 sual acuity (VA), best-corrected VA, digital fundus imaging, visual field testing, and measurement of
170 OOR by multimodal imaging and to analyze the fundus lesions by quantifying short-wavelength fundus au
171 healthy control eyes (P = .03) at equivalent fundus locations.
172 not attenuate relaxation responses in W/W(V) fundus muscles.
173  a result, a fistula with its opening in the fundus of the gall bladder was revealed.
174                             The midposterior fundus of the Sylvian fissure in the human brain is cent
175 Master (Zeiss) axial length measurements and fundus optical coherence tomography (Zeiss).
176 re defined as esophageal, cardia, cardia and fundus or corpus or all of these, corpus, corpus and ant
177 ly to occur in the equator-ora region of the fundus (P < 0.0001), in a diffuse pattern (P < 0.0001),
178 of age had the characteristic dried-out soil fundus pattern (stages 1 and 2).
179            Diabetic retinopathy was based on fundus photograph grading, using the Early Treatment Dia
180 e AMD, assessed by annual masked centralized fundus photograph grading.
181 ons, DME and CSME prevalences from monocular fundus photographs (28.5% and 21.0%, respectively) appro
182 lectance, fundus autofluorescence, and color fundus photographs (CFP).
183 mprehensive eye examination in which dilated fundus photographs (disc and macula centered) were obtai
184                                Two posterior fundus photographs and 1 anterior segment photograph wer
185 monotherapy, including examination of RetCam fundus photographs and fluorescein angiograms.
186                                  Then, color fundus photographs and Humphrey Visual Field tests (HVF)
187                     Based on the analysis of fundus photographs and HVF tests, 25% of these were misd
188 onal study of DME grading based on monocular fundus photographs and OCT images obtained from patients
189 on including color, red-free autofluorescent fundus photographs and spectral-domain optical coherence
190 story, or other covariates or had ungradable fundus photographs and were excluded, leaving 9481 parti
191 agreement of retinal pathologies observed on fundus photographs between an ophthalmologist and two-mi
192  diagnosis, determined from the diagnosis of fundus photographs by 3 experienced readers in combinati
193 the MLOPs and the ophthalmologist in grading fundus photographs for retinal hemorrhages and maculopat
194                                              Fundus photographs from 7 Early Treatment Diabetic Retin
195 and Relevance: In this evaluation of retinal fundus photographs from adults with diabetes, an algorit
196 ined using side-by-side comparisons of color fundus photographs from the initial and final visit as r
197 tep AMD classification system based on color fundus photographs graded by experienced and masked eval
198 ge-related macular degeneration according to fundus photographs graded using a modified Wisconsin Age
199 nosed as not having DME or CSME on monocular fundus photographs have DME on OCT.
200 diagnosed as having DME or CSME on monocular fundus photographs have no DME based on OCT CST, while m
201 ased grading algorithm can be used to screen fundus photographs obtained from diabetic patients and t
202                                              Fundus photographs of 500 eyes of 500 subjects were asse
203                     Phenotypical features on fundus photographs of both eyes of patients were graded
204 ts who were 40 years and older with gradable fundus photographs of the Fourth and the Fifth Korea Nat
205         Prevalence of DME based on monocular fundus photographs or OCT.
206 presence of a notch or disc hemorrhage) from fundus photographs taken with a nonmydriatic portable ca
207 , including FDT perimetry screening, and had fundus photographs taken.
208 ts, slit-lamp examinations, and stereoscopic fundus photographs that were centrally graded for develo
209 gnificant macular edema (CSME), on monocular fundus photographs used definitions from the Multi-Ethni
210 %) were diagnosed as having DME on monocular fundus photographs using MESA and NHANES definitions, re
211 ed as having either DME or CSME on monocular fundus photographs using MESA and NHANES definitions, re
212                   AMD was diagnosed based on fundus photographs using the Rotterdam Classification.
213                                     Gradable fundus photographs were available for 1809 participants
214                                              Fundus photographs were gradable for 665 (90.4%) of thes
215                                              Fundus photographs were graded for drusen and retinal pi
216                                              Fundus photographs were graded using the Wisconsin AMD g
217 .5%) based on MESA definitions for monocular fundus photographs were greater than the DME prevalence
218                                 Nonmydriatic fundus photographs were obtained of each eye and graded
219                                              Fundus photographs were reviewed to assess the presence
220 ehensive ocular evaluation was conducted and fundus photographs were taken to measure the size of the
221 interpreted 40 sets (20 sets with individual fundus photographs with >/=3 fields and 20 computer-gene
222 ined by masked grading of stereoscopic color fundus photographs), and NEI-VFQ-25 subscale scores.
223 the standardized ETDRS severity scale (using fundus photographs).
224 ic retinopathy (NPDR) to PDR based on graded fundus photographs, (2) panretinal photocoagulation (PRP
225                Best-corrected visual acuity, fundus photographs, and spectral-domain optical coherenc
226 Reading center staff evaluated digital color fundus photographs, fluorescein angiography (FA) images,
227 d baseline and follow-up morphology in color fundus photographs, fluorescein angiography (FA), and op
228 lity of procedure, ranibizumab, bevacizumab, fundus photographs, fluorescein angiography, and optical
229                                        Color fundus photographs, fundus autofluorescence, and spectra
230                        Based on stereoscopic fundus photographs, we evaluated diabetic macular edema
231 abetic retinopathy was graded using standard fundus photographs.
232 opathy and diabetic macular edema in retinal fundus photographs.
233 as assessed via grading of color stereo film fundus photographs.
234 randomization with gradable DRSS on baseline fundus photographs.
235  progression of atrophy should include color fundus photography (CFP), confocal fundus autofluorescen
236 sing fundus autofluorescence (FAF) and color fundus photography (CFP).
237  were found using electroretinography (ERG), fundus photography (FP), fundus fluorescein angiography
238 OAG who underwent visual field (VF) testing, fundus photography (FP), other ocular imaging (OOI), or
239 ence of CSME by the following 2 stereoscopic fundus photography (method 1) and dilated biomicroscopy
240 a using indirect ophthalmoscopy (n = 44) and fundus photography (n = 29).
241 valuated the ability of UWFI vs nonmydriatic fundus photography (NMFP) to detect nondiabetic retinal
242 rwent complete ophthalmic examination, color fundus photography (used for AMD staging), and spectral-
243        Case notes and retinal imaging (color fundus photography [CFP], spectral-domain [SD] optical c
244 ccur in AMD than can be detected using color fundus photography alone.
245 ed Maculopathy Staging system based on color fundus photography and a masked grader.
246 e change assessed by masked grading of color fundus photography and Early Treatment Diabetic Retinopa
247                                        Color fundus photography and fluorescein angiography (FA) imag
248 rfusion status using standard 7-field stereo fundus photography and fluorescein angiography, respecti
249  evaluated by repeated ophthalmoscopy, color fundus photography and fluorescein fundus angiography, b
250 th clinically confirmed RAH were imaged with fundus photography and SD OCT.
251             These patients had all undergone fundus photography and spectral-domain optical coherence
252 aracteristics that indicated AMD revealed by fundus photography and trained raters.
253 of the structure-function relationship using fundus photography and visual field sensitivity are exam
254  type 1 or 2 diabetes underwent nonmydriatic fundus photography for a diabetic retinopathy screening
255 d epidemiological studies rely on monoscopic fundus photography for the detection of clinically signi
256 ic fundus photography, and 7-field mydriatic fundus photography for their abilities to detect and gra
257 articipants underwent dilated stereo-digital fundus photography graded according to the International
258 , and macular edema, as well as stereoscopic fundus photography of 7 standard Early Treatment Diabeti
259 .78 mm(2)/year), assessed primarily by color fundus photography or fundus autofluorescence (FAF) imag
260 ned by means of a 3-mm OCTA scan and 7-field fundus photography using the Diabetic Retinopathy Severi
261 tinal screening examination and nonmydriatic fundus photography via the Intelligent Retinal Imaging S
262  diabetic macular edema (DME) from monocular fundus photography vs optical coherence tomography (OCT)
263 remote graders in detecting CMV retinitis on fundus photography was 30.2% (95% CI, 10.5%-52.4%), and
264 ved complete success, but in only 6% initial fundus photography was unsuccessful, indicating its valu
265 tients, and in 13 (6%; 95%CI, 3-10) patients fundus photography was unsuccessful.
266 as used to quantify choroidal thickness, and fundus photography was used to classify eyes into catego
267                                 Nonmydriatic fundus photography with remote interpretation by an expe
268  smartphone fundus photography, nonmydriatic fundus photography, and 7-field mydriatic fundus photogr
269  ROP, as determined by clinical examination, fundus photography, and fluorescein angiography.
270 tical coherence tomography, wide-field color fundus photography, and fluorescein angiography.
271                          Case notes, digital fundus photography, and spectral-domain optical coherenc
272 derwent imaging with B-scan ultrasonography, fundus photography, autofluorescence, fluorescein angiog
273 e ophthalmologic examination including color fundus photography, fluorescein and indocyanine green an
274       Multimodal imaging findings, including fundus photography, fluorescein angiography, spectral-do
275 est-corrected visual acuity, ophthalmoscopy, fundus photography, full-field electroretinography (ffER
276 s, including full-field electroretinography, fundus photography, fundus autofluorescence imaging, and
277 noninvasive multimodal imaging that included fundus photography, near-infrared reflectance, blue auto
278                       We compared smartphone fundus photography, nonmydriatic fundus photography, and
279                                              Fundus photography, OCT, fluorescein angiography (FA), a
280                            Here, we employed fundus photography, spectral domain optical coherence to
281                     Indirect ophthalmoscopy, fundus photography, ultrasonography, and ultrasonic biom
282             All participants underwent color fundus photography, used for AMD diagnosis and staging,
283 ectance, fluorescein angiography, as well as fundus photography, were also recorded.
284 lemedicine screening typically use monocular fundus photography, while treatment of DME uses OCT CST.
285  acute and chronic, underwent OCTA and color fundus photography.
286 ldmann applanation tonometry, gonioscopy and fundus photography.
287 f disc images on par with standard mydriatic fundus photography.
288 ensive ocular examination, including dilated fundus photography.
289 ng by OCT, pseudocolor, and autofluorescence fundus photography.
290 ve and objective refraction and stereoscopic fundus photography.
291  use, sunlight exposure, and diet; underwent fundus photography.
292 -lamp examination, intraocular pressure, and fundus photography.
293                               Twelve (2.4 %) fundus pictures were non-gradable.
294  the help of the stereoscopic picture of the fundus provided by the endoscope, a poor visual prognosi
295 ll comprehensive ophthalmologic examination, fundus retinography, Goldmann kinetic visual field (GVF)
296 ups, the white opacity of the infract in the fundus seen during the acute phase gradually resolved in
297 al imaging (MSI) creates a series of en-face fundus spectral sections by leveraging an extensive rang
298 eeks, leaving greyish, granular, depigmented fundus, unmasking of the large choroidal vessels and opt
299    Transarterial embolization of the gastric fundus with fluoroscopic guidance was performed with 300
300 ins) eyes show discolouration of the tapetal fundus with varying onset and disease progression, while

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